Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0346 | 0.8676 | 1 |
Leishmania major | 0.0346 | 0.8676 | 0.5 | |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0346 | 0.8676 | 0.8676 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0346 | 0.8676 | 0.5 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0346 | 0.8676 | 0.5 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0346 | 0.8676 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0373 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0346 | 0.8676 | 0.5 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0346 | 0.8676 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0202 | 0.1439 | 0.1439 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0199 | 0.126 | 0.126 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0202 | 0.1439 | 0.1439 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0346 | 0.8676 | 0.5 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0346 | 0.8676 | 0.8676 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.