Detailed information for compound 253461

Basic information

Technical information
  • TDR Targets ID: 253461
  • Name: (4-hydroxyphenyl)-(7-methoxy-6-phenylmethoxyi soquinolin-1-yl)methanone
  • MW: 385.412 | Formula: C24H19NO4
  • H donors: 1 H acceptors: 3 LogP: 4.86 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2c(cc1OCc1ccccc1)ccnc2C(=O)c1ccc(cc1)O
  • InChi: 1S/C24H19NO4/c1-28-21-14-20-18(13-22(21)29-15-16-5-3-2-4-6-16)11-12-25-23(20)24(27)17-7-9-19(26)10-8-17/h2-14,26H,15H2,1H3
  • InChiKey: WCUYLCITKRJRIP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (6-benzyloxy-7-methoxy-1-isoquinolyl)-(4-hydroxyphenyl)methanone
  • (4-hydroxyphenyl)-(7-methoxy-6-phenylmethoxy-isoquinolin-1-yl)methanone
  • (6-benzoxy-7-methoxy-1-isoquinolyl)-(4-hydroxyphenyl)methanone
  • (4-hydroxyphenyl)-[7-methoxy-6-(phenylmethoxy)isoquinolin-1-yl]methanone
  • (4-hydroxyphenyl)-[7-methoxy-6-(phenylmethoxy)-1-isoquinolyl]methanone
  • [6-(benzyloxy)-7-methoxy-1-isoquinolyl]-(4-hydroxyphenyl)methanone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.038 0.1527 0.6674
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) histone methyltransferase 0.0027 0.0025 0.0061
Trypanosoma cruzi cruzipain precursor, putative 0.0174 0.0653 0.1573
Brugia malayi Trypsin-like protease protein 5 0.0038 0.0072 0.0174
Plasmodium vivax vivapain-2 0.0555 0.2268 1
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0368 0.1621
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0072 0.0175
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.086 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0441 0.1061
Onchocerca volvulus 0.0038 0.0072 0.0143
Toxoplasma gondii proteasome subunit beta type, putative 0.007 0.0208 0.0917
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.116 0.5115
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Onchocerca volvulus 0.0038 0.0072 0.0143
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0038 0.0072 0.0141
Trypanosoma cruzi kinesin, putative 0.0028 0.0031 0.0075
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0072 0.0142
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0186 0.0448
Plasmodium falciparum cysteine proteinase falcipain 3 0.0555 0.2268 1
Giardia lamblia Hypothetical protein 0.0124 0.0441 0.2774
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0072 0.0142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0009 0.0039
Brugia malayi GnHR receptor homolog 0.0038 0.0072 0.0175
Echinococcus granulosus fmrfamide receptor 0.0038 0.0072 0.0142
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.0431 0.0843
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0178 0.0428
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni hypothetical protein 0.0165 0.0612 0.1199
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0061 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0441 0.1943
Echinococcus granulosus importin subunit beta 1 0.0028 0.0031 0.0062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0072 0.0142
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0198
Echinococcus multilocularis cpg binding protein 0.0091 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0174 0.0653 0.1573
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0061 0.0206
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0499
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0082 0.0198
Brugia malayi Trypsin family protein 0.0038 0.0072 0.0174
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0044 0.0044
Echinococcus granulosus serotonin receptor 0.0038 0.0072 0.0142
Plasmodium falciparum importin beta, putative 0.0028 0.0031 0.0139
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0072 0.0175
Entamoeba histolytica hypothetical protein 0.0035 0.006 0.0267
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0088 0.039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0299 0.1182 0.5209
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0072 0.0142
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Schistosoma mansoni cathepsin F (C01 family) 0.0555 0.2268 0.4442
Echinococcus granulosus cathepsin L cysteine protease 0.0299 0.1182 0.2314
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0061 0.0267
Loa Loa (eye worm) hypothetical protein 0.038 0.1527 0.3679
Entamoeba histolytica cysteine proteinase, putative 0.038 0.1527 0.6734
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0441 0.1943
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0186 0.0448
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0072 0.0142
Brugia malayi beta-lactamase 0.0035 0.0061 0.0146
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Brugia malayi Peroxidasin 0.0064 0.0186 0.0448
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0072 0.0072
Loa Loa (eye worm) calpain 5 0.0028 0.0031 0.0075
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0072 0.0142
Echinococcus multilocularis serotonin receptor 0.0038 0.0072 0.0072
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0555 0.2268 0.2268
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.0174 0.0653 0.1573
Onchocerca volvulus 0.0096 0.032 0.1256
Leishmania major hypothetical protein, conserved 0.021 0.0802 0.3538
Trypanosoma brucei antigen, putative 0.004 0.0082 0.0362
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0072 0.0142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Onchocerca volvulus 0.0038 0.0072 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0441 0.1943
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0072 0.0072
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0299 0.1182 0.2314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0083 0.0264 0.0264
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0121 0.0942
Brugia malayi Blistered cuticle protein 3 0.0064 0.0186 0.0448
Echinococcus granulosus snurportin 1 0.0299 0.1184 0.2319
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0111 0.0383 0.0749
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0124 0.0441 0.1943
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Giardia lamblia Cathepsin B precursor 0.0124 0.0441 0.2774
Onchocerca volvulus Cathepsin F homolog 0.0555 0.2268 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0555 0.2268 0.2268
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0044 0.0193
Echinococcus granulosus tumor protein p63 0.0656 0.27 0.5287
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.007 0.0208 0.0407
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0072 0.0175
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0197 0.0751 0.1808
Entamoeba histolytica hypothetical protein 0.0023 0.0009 0.0039
Trypanosoma brucei calpain-like protein, putative 0.004 0.0082 0.0362
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0072 0.0175
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0135 0.0485 0.0951
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0368 0.3972
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0124 0.0441 0.1943
Mycobacterium ulcerans hypothetical protein 0.0069 0.0207 0.2881
Schistosoma mansoni hypothetical protein 0.0062 0.0178 0.0348
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0311 0.075
Echinococcus granulosus g protein coupled receptor 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Onchocerca volvulus 0.0555 0.2268 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.038 0.1527 0.6734
Trypanosoma brucei Aph-1 protein, putative 0.0283 0.1116 0.4922
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0555 0.2268 1
Echinococcus multilocularis cathepsin b 0.0998 0.4152 0.4152
Brugia malayi beta-lactamase family protein 0.0035 0.0061 0.0146
Brugia malayi Trypsin family protein 0.0038 0.0072 0.0174
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.006 0.0118
Loa Loa (eye worm) hypothetical protein 0.0124 0.0441 0.1061
Entamoeba histolytica hypothetical protein 0.0124 0.0441 0.1943
Onchocerca volvulus 0.0038 0.0072 0.0143
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0035 0.0156
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0156
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0072 0.0175
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0035 0.0156
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0072 0.0142
Entamoeba histolytica cysteine proteinase 2 0.0299 0.1182 0.5209
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Trypanosoma cruzi Aph-1 protein, putative 0.0283 0.1116 0.2689
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0035 0.0156
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0126 0.0304
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0368 0.1621
Brugia malayi G-protein coupled receptor 0.0038 0.0072 0.0175
Onchocerca volvulus 0.0038 0.0072 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0124 0.0441 0.0863
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0072 0.0175
Echinococcus granulosus calpain A 0.0111 0.0383 0.0749
Giardia lamblia Cathepsin L-like protease 0.0124 0.0441 0.2774
Brugia malayi Papain family cysteine protease containing protein 0.0299 0.1182 0.2846
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0441 0.1943
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0076 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.002
Echinococcus granulosus cathepsin L cysteine proteinase 0.0555 0.2268 0.4442
Giardia lamblia Cathepsin L precursor 0.0124 0.0441 0.2774
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0072 0.0142
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0025 0.0049
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0186 0.0653
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0072 0.0175
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0072 0.0072
Leishmania major hypothetical protein, conserved 0.0035 0.0061 0.0267
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0035 0.0223
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0998 0.4152 0.813
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0111 0.0383 0.0749
Toxoplasma gondii hypothetical protein 0.0047 0.0114 0.0501
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni hypothetical protein 0.008 0.0251 0.0492
Giardia lamblia Cathepsin L precursor 0.0124 0.0441 0.2774
Echinococcus granulosus hypothetical protein 0.0038 0.0072 0.0142
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0031 0.0139
Plasmodium falciparum cysteine proteinase falcipain 1 0.0299 0.1182 0.5209
Brugia malayi Niemann-Pick C1 protein precursor 0.0193 0.0732 0.1762
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0035 0.0156
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0998 0.4152 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0061 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0555 0.2268 0.5463
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0368 0.0886
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0072 0.0142
Giardia lamblia Cathepsin B precursor 0.0124 0.0441 0.2774
Echinococcus multilocularis proteasome (prosome, macropain) 0.007 0.0208 0.0208
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0044 0.0044
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0044 0.0193
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0368 0.1621
Brugia malayi putative neuropeptide receptor 0.0038 0.0072 0.0175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Brugia malayi 6-phosphofructokinase 0.0107 0.0368 0.0886
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0178 0.0348
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0998 0.4152 0.813
Giardia lamblia Cathepsin L precursor 0.0124 0.0441 0.2774
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0555 0.2268 0.2268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Echinococcus granulosus sterol regulatory element binding protein 0.0083 0.0264 0.0517
Entamoeba histolytica cysteine protease, putative 0.0124 0.0441 0.1943
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0072 0.0072
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0072 0.0175
Trypanosoma cruzi major cysteine proteinase, putative 0.0124 0.0441 0.1061
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0124 0.0441 0.2774
Echinococcus granulosus Protein patched homolog 1 0.0083 0.0264 0.0517
Giardia lamblia Hypothetical protein 0.0124 0.0441 0.2774
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0186 0.0653
Echinococcus multilocularis transmembrane protease serine 3 0.0038 0.0072 0.0072
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Echinococcus multilocularis Mastin 0.0038 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Brugia malayi cathepsin L-like precursor 0.038 0.1527 0.3679
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0078 0.0244 0.0587
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0072
Schistosoma mansoni cellular tumor antigen P53 0.0096 0.032 0.0627
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Loa Loa (eye worm) ctsf protein 0.0555 0.2268 0.5463
Onchocerca volvulus 0.0038 0.0072 0.0143
Trypanosoma cruzi cysteine protease, putative 0.0299 0.1182 0.2846
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0031 0.0139
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0072 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0069 0.0207 0.2881
Schistosoma mansoni hypothetical protein 0.008 0.0251 0.0492
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0395 0.1588 0.7003
Brugia malayi Serotonin receptor 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0052 0.0133 0.032
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0072 0.0072
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0186 0.0653
Plasmodium falciparum proteasome subunit beta type-5 0.007 0.0208 0.0917
Echinococcus granulosus cysteine protease 0.0299 0.1182 0.2314
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0299 0.1182 0.2846
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0072 0.0072
Entamoeba histolytica calpain large subunit domain III containing protein 0.0028 0.0031 0.0137
Echinococcus multilocularis chromobox protein 1 0.0069 0.0204 0.0204
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0044 0.0193
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0052 0.0133 1
Schistosoma mansoni amine GPCR 0.0038 0.0072 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0069 0.0207 0.2881
Onchocerca volvulus 0.0038 0.0072 0.0141
Brugia malayi RE15519p 0.0038 0.0072 0.0175
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0186 0.0448
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0101 0.0343 0.0826
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Plasmodium falciparum serine repeat antigen 8 0.0124 0.0441 0.1943
Trypanosoma cruzi cysteine peptidase, putative 0.0555 0.2268 0.5463
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0072 0.0072
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0193 0.0732 0.3225
Mycobacterium tuberculosis Conserved protein 0.0035 0.0061 0.0206
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.0906 0.2182
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0072 0.0142
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0124 0.0441 0.1061
Echinococcus multilocularis tissue type plasminogen activator 0.021 0.0802 0.0802
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0069 0.0207 0.2881
Echinococcus granulosus cathepsin L 0.0124 0.0441 0.0863
Schistosoma mansoni hypothetical protein 0.008 0.0251 0.0492
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0178 0.0348
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0124 0.0441 0.1943
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0069 0.0207 0.2881
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0043 0.0188
Echinococcus granulosus neuropeptide receptor 0.0038 0.0072 0.0142
Echinococcus granulosus tissue type plasminogen activator 0.021 0.0802 0.1571
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0072 0.0142
Brugia malayi Papain family cysteine protease containing protein 0.0124 0.0441 0.1061
Mycobacterium tuberculosis Conserved protein 0.0035 0.0061 0.0206
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0146
Loa Loa (eye worm) hypothetical protein 0.0052 0.0133 0.032
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0069 0.0207 0.2881
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0124 0.0441 0.1943
Schistosoma mansoni opsin-like receptor 0.0038 0.0072 0.0142
Toxoplasma gondii cathepsin B 0.0395 0.1588 0.7003
Echinococcus granulosus glycoprotein Antigen 5 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0083 0.0264 0.0636
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0044 0.0105
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0072 0.0142
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0156
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0069 0.0207 0.2881
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi hypothetical protein 0.0064 0.0186 0.0448
Entamoeba histolytica cysteine proteinase, putative 0.0299 0.1182 0.5209
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0061 0.0119
Leishmania major proteasome beta 5 subunit, putative 0.007 0.0208 0.0917
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0072 0.0142
Echinococcus granulosus cathepsin b 0.0998 0.4152 0.813
Schistosoma mansoni cpg binding protein 0.0091 0.0298 0.0583
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Onchocerca volvulus 0.0066 0.0193 0.0682
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0044 0.0193
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.038 0.1527 0.3679
Echinococcus granulosus cpg binding protein 0.0091 0.0298 0.0583
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0069 0.0207 0.2004
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0044 0.0193
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0124 0.0441 0.1943
Echinococcus granulosus dnaJ subfamily B 0.1223 0.5107 1
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0072 0.0175
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0072 0.0142
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0072 0.0072
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0182 0.0686 0.1343
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0998 0.4152 0.813
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0368 0.6035
Leishmania major kinesin, putative 0.0028 0.0031 0.0137
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0044 0.0193
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0728 0.3003 0.7232
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0264 0.1163
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0204 0.09
Giardia lamblia Cathepsin B precursor 0.0395 0.1588 1
Brugia malayi MH2 domain containing protein 0.0234 0.0906 0.2182
Echinococcus granulosus Niemann Pick C1 protein 0.0276 0.1083 0.2121
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0124 0.0441 0.1061
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0038 0.0072 0.0174
Giardia lamblia Cathepsin L precursor 0.0124 0.0441 0.2774
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0555 0.2268 0.5463
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Onchocerca volvulus 0.0038 0.0072 0.0143
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0072 0.0175
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0555 0.2268 0.5463
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0072 0.0072
Brugia malayi Papain family cysteine protease containing protein 0.0124 0.0441 0.1061
Schistosoma mansoni peroxidasin 0.0064 0.0186 0.0364
Loa Loa (eye worm) cathepsin B 0.0395 0.1588 0.3826
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0035 0.0156
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0072 0.0072
Plasmodium falciparum serine repeat antigen 1 0.0124 0.0441 0.1943
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0072 0.0142
Echinococcus multilocularis dnaJ subfamily B 0.1223 0.5107 0.5107
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0072 0.0142
Schistosoma mansoni biogenic amine receptor 0.0038 0.0072 0.0142
Brugia malayi AMP-binding enzyme family protein 0.0069 0.0207 0.0499
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0061 0.0146
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0072 0.0072
Echinococcus granulosus cathepsin l1 0.038 0.1527 0.2991
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0024 0.0057
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.116 0.2794
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0044 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0043 0.0188
Trypanosoma cruzi cysteine peptidase, putative 0.0555 0.2268 0.5463
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0061 0.0119
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0277 0.0667
Echinococcus granulosus orexin receptor type 2 0.0038 0.0072 0.0142
Leishmania major 4-coumarate:coa ligase-like protein 0.0069 0.0207 0.0914
Echinococcus multilocularis snurportin 1 0.0299 0.1184 0.1184
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trypanosoma brucei calpain-like protein, putative 0.004 0.0082 0.0362
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0061 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0299 0.1182 0.5209
Entamoeba histolytica cysteine protease, putative 0.0124 0.0441 0.1943
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0052 0.0133 0.109
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.004 0.0082 0.0362
Schistosoma mansoni neuropeptide receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0124 0.0441 0.1061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0441 0.1061
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0088 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0441 0.1943
Onchocerca volvulus 0.0038 0.0072 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Loa Loa (eye worm) calpain family protein 1 0.0106 0.0362 0.0873
Loa Loa (eye worm) hypothetical protein 0.0039 0.0076 0.0183
Giardia lamblia Cathepsin B precursor 0.0124 0.0441 0.2774
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0124 0.0441 0.1943
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0186 0.0448
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0362
Schistosoma mansoni neuropeptide receptor 0.0038 0.0072 0.0142
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0004 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0072 0.0072
Toxoplasma gondii ABC1 family protein 0.0035 0.0061 0.0267
Brugia malayi AMP-binding enzyme family protein 0.0069 0.0207 0.0499
Onchocerca volvulus 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0052 0.0133 0.032
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.0431 0.0431
Loa Loa (eye worm) trypsin family protein 0.0038 0.0072 0.0174
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Leishmania major 4-coumarate:coa ligase-like protein 0.0069 0.0207 0.0914
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0368 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0088 0.0211
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0061 0.0206
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0038 0.0072 0.0141
Brugia malayi cathepsin L-like cysteine proteinase 0.0124 0.0441 0.1061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Echinococcus granulosus somatostatin receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0044 0.0105
Plasmodium vivax unspecified product 0.0174 0.0653 0.288
Onchocerca volvulus 0.0038 0.0072 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0368 0.1621
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0043 0.0188
Giardia lamblia Cathepsin B precursor 0.0124 0.0441 0.2774
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0121 0.0942
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0072 0.0072
Loa Loa (eye worm) TK/ROR protein kinase 0.021 0.0802 0.1933
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0061 0.0206
Trypanosoma cruzi major cysteine proteinase, putative 0.0124 0.0441 0.1061
Onchocerca volvulus 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0044 0.0105
Echinococcus multilocularis Niemann Pick C1 protein 0.0193 0.0732 0.0732
Entamoeba histolytica hypothetical protein 0.0035 0.006 0.0267
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0061 0.0146
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0035 0.0156
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0555 0.2268 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0174 0.0653 0.1573
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0038 0.0072 0.0141
Giardia lamblia Proteasome subunit beta type 5 precursor 0.007 0.0208 0.1309
Brugia malayi gamma-secretase subunit aph-1 0.0728 0.3003 0.7232
Trypanosoma cruzi cruzipain precursor, putative 0.0555 0.2268 0.5463
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0072 0.0142
Schistosoma mansoni cpg binding protein 0.0086 0.0277 0.0542
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0156
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0072 0.0142
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0503 0.2217
Entamoeba histolytica cysteine protease, putative 0.0124 0.0441 0.1943
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0555 0.2268 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0124 0.0441 0.1943
Schistosoma mansoni cathepsin F (C01 family) 0.0555 0.2268 0.4442
Giardia lamblia Encystation-specific protease 0.0124 0.0441 0.2774
Onchocerca volvulus 0.0038 0.0072 0.0143
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0061 0.0206
Plasmodium falciparum serine repeat antigen 3 0.0124 0.0441 0.1943
Onchocerca volvulus 0.0035 0.0061 0.009
Onchocerca volvulus 0.0124 0.0441 0.1796
Echinococcus granulosus gamma secretase subunit aph 1 0.0728 0.3003 0.588
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Plasmodium vivax unspecified product 0.0299 0.1182 0.5209
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0124 0.0441 0.1943
Loa Loa (eye worm) hypothetical protein 0.0174 0.0653 0.1573
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.1184 0.2852
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Schistosoma mansoni cathepsin B (C01 family) 0.0124 0.0441 0.0863
Brugia malayi G protein-coupled receptor 0.0038 0.0072 0.0175
Onchocerca volvulus 0.0038 0.0072 0.0143
Mycobacterium ulcerans proteasome PrcB 0.007 0.0208 0.2896
Plasmodium vivax serine-repeat antigen (SERA) 0.0124 0.0441 0.1943
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0072 0.0072
Echinococcus granulosus allatostatin A receptor 0.0038 0.0072 0.0142
Schistosoma mansoni hypothetical protein 0.0038 0.0072 0.0142
Leishmania major 4-coumarate:coa ligase-like protein 0.0069 0.0207 0.0914
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0204 0.0492
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0038 0.0072 0.0072
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Giardia lamblia Cysteine protease 0.0124 0.0441 0.2774
Onchocerca volvulus 0.0035 0.0061 0.009
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0035 0.0156
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0061 0.0267
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Entamoeba histolytica cysteine protease, putative 0.0124 0.0441 0.1943
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0124 0.0441 0.1943
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.0802 0.1933
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0061 0.0119
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0362
Schistosoma mansoni thyroid hormone receptor 0.0142 0.0515 0.1008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0088 0.0211
Loa Loa (eye worm) hypothetical protein 0.0135 0.0485 0.1169
Giardia lamblia Cysteine protease 0.0124 0.0441 0.2774
Entamoeba histolytica cysteine protease, putative 0.0555 0.2268 1
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0072 0.0072
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.0751 0.1808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0368 0.1621
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Brugia malayi calpain family protein 1 0.0106 0.0362 0.0873
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Plasmodium vivax vivapain-3 0.0299 0.1182 0.5209
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0072 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0082 0.0198
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Schistosoma mansoni hypothetical protein 0.1223 0.5107 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0198
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0174 0.0653 0.1573
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0069 0.0207 0.4775
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0124 0.0441 0.1061
Schistosoma mansoni cathepsin s 0.0174 0.0653 0.1279
Loa Loa (eye worm) hypothetical protein 0.0193 0.0732 0.1762
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0061 0.0267
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Brugia malayi Heterochromatin protein 1 0.0069 0.0204 0.0492
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0124 0.0441 0.1943
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0368 0.0886
Schistosoma mansoni patched 1 0.0083 0.0264 0.0517
Brugia malayi beta-lactamase family protein 0.0035 0.0061 0.0146
Onchocerca volvulus 0.0038 0.0072 0.0143
Brugia malayi Kringle domain containing protein 0.021 0.0802 0.1933
Echinococcus multilocularis protein patched 0.0083 0.0264 0.0264
Schistosoma mansoni gamma-secretase subunit aph-1 0.0728 0.3003 0.588
Schistosoma mansoni cathepsin F (C01 family) 0.038 0.1527 0.2991
Echinococcus granulosus Mastin 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0072 0.0142
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0072 0.0072
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0124 0.0441 0.1943
Trypanosoma cruzi cysteine proteinase, putative 0.0299 0.1182 0.2846
Plasmodium vivax vivapain-2 0.0555 0.2268 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.0906 0.2182
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0072 0.0072
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0069 0.0207 0.2881
Echinococcus multilocularis chromobox protein 1 0.0069 0.0204 0.0204
Brugia malayi Importin beta-1 subunit 0.0028 0.0031 0.0076
Brugia malayi Protein kinase domain containing protein 0.021 0.0802 0.1933
Brugia malayi cathepsin F-like cysteine proteinase 0.0124 0.0441 0.1061
Brugia malayi G-protein coupled receptor 0.0038 0.0072 0.0175
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0069 0.0207 0.4775
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0076 0.0159
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0441 0.0863
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0072 0.0175
Echinococcus granulosus chromobox protein 1 0.0069 0.0204 0.04
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0072 0.0175
Schistosoma mansoni peroxidasin 0.0064 0.0186 0.0364
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0441 0.0863
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.007 0.0208 0.0501
Entamoeba histolytica cysteine proteinase 1, putative 0.0299 0.1182 0.5209
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0441 0.0863
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0003 0.0003
Brugia malayi Cathepsin L-like cysteine proteinase 0.038 0.1527 0.3679
Brugia malayi Melatonin receptor type 1A 0.0038 0.0072 0.0175
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Echinococcus granulosus calpain 5 0.004 0.0082 0.0161
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0086
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0072 0.0142
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0009 0.0021
Echinococcus multilocularis somatostatin receptor 0.0038 0.0072 0.0072
Brugia malayi fibroinase precursor 0.0124 0.0441 0.1061
Echinococcus granulosus cathepsin b 0.0998 0.4152 0.813
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Onchocerca volvulus 0.0064 0.0186 0.0653
Entamoeba histolytica acyl-CoA synthetase, putative 0.0069 0.0207 0.0914
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0121 0.0942
Schistosoma mansoni cathepsin C 0.0124 0.0441 0.0863
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0038 0.0072 0.0175
Schistosoma mansoni amine GPCR 0.0038 0.0072 0.0142
Brugia malayi phosphofructokinase 0.0107 0.0368 0.0886
Plasmodium vivax calpain, putative 0.004 0.0082 0.0362
Echinococcus multilocularis Niemann Pick C1 protein 0.0276 0.1083 0.1083
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0368 0.072
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0072 0.0142
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0395 0.1588 0.7003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0072 0.0072
Onchocerca volvulus 0.0038 0.0072 0.0143
Mycobacterium ulcerans hypothetical protein 0.0038 0.0072 0.0226
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0441 0.0863
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0072 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0368 1
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.007 0.0208 0.0917
Loa Loa (eye worm) calpain family protein 1 0.0078 0.0244 0.0587
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0061 0.0267
Onchocerca volvulus 0.0038 0.0072 0.0143
Plasmodium vivax vivapain-1 0.0299 0.1182 0.5209
Echinococcus granulosus GPCR family 2 0.0062 0.0178 0.0348
Brugia malayi Cathepsin L-like precursor 0.0555 0.2268 0.5463
Schistosoma mansoni calpain-7 (C02 family) 0.004 0.0082 0.0161
Loa Loa (eye worm) hypothetical protein 0.038 0.1527 0.3679
Onchocerca volvulus 0.0064 0.0186 0.0653
Onchocerca volvulus 0.0064 0.0186 0.0653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0555 0.2268 0.2268
Trypanosoma cruzi kinesin, putative 0.0028 0.0031 0.0075
Plasmodium falciparum serine repeat antigen 6 0.0124 0.0441 0.1943
Trypanosoma cruzi cysteine peptidase, putative 0.0555 0.2268 0.5463
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0555 0.2268 1
Entamoeba histolytica cysteine proteinase, putative 0.0555 0.2268 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0124 0.0441 0.2774
Onchocerca volvulus Cathepsin L homolog 0.0124 0.0441 0.1796
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni myosin xvIII 0.0038 0.0072 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0028 0.0124
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0299 0.1182 0.2314
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.038 0.1527 0.3679
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0044
Schistosoma mansoni neuropeptide receptor 0.0038 0.0072 0.0142
Brugia malayi larval opioid receptor 0.0038 0.0072 0.0175
Echinococcus granulosus calpain 0.004 0.0082 0.0161
Brugia malayi chromobox protein homolog 3 0.0039 0.0076 0.0183
Echinococcus granulosus peroxidasin 0.0064 0.0186 0.0364
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0204 0.09
Onchocerca volvulus 0.0555 0.2268 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0072 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0043 0.0188
Echinococcus granulosus cathepsin l1 0.0555 0.2268 0.4442
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0124 0.0441 0.1943
Schistosoma mansoni hypothetical protein 0.0062 0.0178 0.0348
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0395 0.1588 0.3826
Brugia malayi neuropeptide F receptor 0.0038 0.0072 0.0175
Trypanosoma cruzi cysteine peptidase, putative 0.0555 0.2268 0.5463
Giardia lamblia Cathepsin B precursor 0.0395 0.1588 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0124 0.0441 0.1943
Brugia malayi CHE-14 protein 0.0083 0.0264 0.0636
Giardia lamblia Cathepsin L precursor 0.0124 0.0441 0.2774
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Onchocerca volvulus 0.021 0.0802 0.342
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0072 0.0142
Brugia malayi ORL1-like opioid receptor 0.0038 0.0072 0.0175
Entamoeba histolytica cysteine protease, putative 0.0124 0.0441 0.1943
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0156
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0362
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0072 0.0142
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0197 0.0751 0.1808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0441 0.0863
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0186 0.0448
Toxoplasma gondii cathepsin CPL 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Plasmodium falciparum serine repeat antigen 5 0.0124 0.0441 0.1943
Echinococcus multilocularis cysteine protease 0.0555 0.2268 0.2268
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0998 0.4152 0.813
Echinococcus granulosus transmembrane protease serine 3 0.0038 0.0072 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0124 0.0441 0.1943
Mycobacterium leprae proteasome (beta subunit) PrcB 0.007 0.0208 0.4799
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0178 0.0428
Onchocerca volvulus 0.0086 0.0277 0.1061
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0025 0.0025
Echinococcus multilocularis cysteine protease 0.0555 0.2268 0.2268
Echinococcus multilocularis sex peptide receptor 0.0038 0.0072 0.0072
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Schistosoma mansoni hypothetical protein 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0124 0.0441 0.1061
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.116 0.5115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni hypothetical protein 0.0062 0.0178 0.0348
Entamoeba histolytica cysteine proteinase, putative 0.0299 0.1182 0.5209
Toxoplasma gondii preprocathepsin c precursor, putative 0.0124 0.0441 0.1943
Trypanosoma cruzi Aph-1 protein, putative 0.0283 0.1116 0.2689
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0072 0.0072
Schistosoma mansoni opsin-like receptor 0.0038 0.0072 0.0142
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0503 0.1211
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Entamoeba histolytica cysteine proteinase, putative 0.0299 0.1182 0.5209
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0088 0.0214
Brugia malayi calpain 7 0.004 0.0082 0.0198
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0009 0.0039
Echinococcus multilocularis tumor protein p63 0.0656 0.27 0.27
Onchocerca volvulus 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Plasmodium falciparum cysteine repeat modular protein 1 0.021 0.0802 0.3538
Schistosoma mansoni opsin-like receptor 0.0038 0.0072 0.0142
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0082 0.0198
Brugia malayi calpain family protein 1 0.0106 0.0362 0.0873
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0072 0.0072
Brugia malayi Cathepsin L-like precursor 0.038 0.1527 0.3679
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0395 0.1588 0.3111
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0072 0.0142
Toxoplasma gondii histone lysine methyltransferase SET1 0.0163 0.0603 0.266
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Plasmodium vivax importin-beta 2, putative 0.0028 0.0031 0.0139
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0072 0.0142
Schistosoma mansoni biogenic amine receptor 0.0038 0.0072 0.0142
Schistosoma mansoni hypothetical protein 0.0062 0.0178 0.0348
Echinococcus granulosus Niemann Pick C1 protein 0.0193 0.0732 0.1433
Echinococcus multilocularis thyroid hormone receptor alpha 0.0142 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Schistosoma mansoni hypothetical protein 0.0038 0.0072 0.0142
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0061 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0368 0.1621
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.057 0.6446
Loa Loa (eye worm) hypothetical protein 0.0124 0.0441 0.1061
Onchocerca volvulus 0.0038 0.0072 0.0143
Giardia lamblia Cysteine protease 0.0124 0.0441 0.2774
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0499
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0124 0.0441 0.1943
Entamoeba histolytica cysteine proteinase, putative 0.0555 0.2268 1
Onchocerca volvulus Cathepsin L homolog 0.0555 0.2268 1
Onchocerca volvulus 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0098
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0124 0.0441 0.1943
Onchocerca volvulus 0.0038 0.0072 0.0143
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0082 0.0198
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0121 0.0942
Brugia malayi sulfakinin receptor protein 0.0038 0.0072 0.0175
Onchocerca volvulus Peroxidase homolog 0.0064 0.0186 0.0653
Brugia malayi Cathepsin L-like precursor 0.038 0.1527 0.3679
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.0998 0.4152 1
Plasmodium falciparum serine repeat antigen 9 0.0124 0.0441 0.1943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0299 0.1182 0.5209
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0124 0.0441 0.1943
Loa Loa (eye worm) hypothetical protein 0.021 0.0802 0.1933
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0003 0.0006
Mycobacterium tuberculosis Conserved protein 0.0035 0.0061 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0028 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0441 0.1943
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.007 0.0208 0.0501
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi neuropeptide F receptor 0.0038 0.0072 0.0175
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.006 0.006
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0124 0.0441 0.1943
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0088 0.039
Brugia malayi AMP-binding enzyme family protein 0.0069 0.0207 0.0499
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0076
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0198
Brugia malayi Cathepsin L-like precursor 0.0555 0.2268 0.5463
Trypanosoma brucei cysteine peptidase C (CPC) 0.0395 0.1588 0.7003
Giardia lamblia Cathepsin L precursor 0.0124 0.0441 0.2774
Echinococcus multilocularis hypothetical protein 0.004 0.0082 0.0082
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0124 0.0441 0.0863
Schistosoma mansoni amine GPCR 0.0038 0.0072 0.0142
Schistosoma mansoni histamine h1 receptor 0.0038 0.0072 0.0142
Schistosoma mansoni calpain-7 (C02 family) 0.004 0.0082 0.0161
Loa Loa (eye worm) hypothetical protein 0.0174 0.0653 0.1573
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0072 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0043 0.0188
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0072 0.0142
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0124 0.0441 0.1943
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0111 0.0383 0.0749
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0031 0.0139
Schistosoma mansoni cpg binding protein 0.0091 0.0298 0.0583
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0146
Onchocerca volvulus 0.0038 0.0072 0.0143
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0368 0.1621
Schistosoma mansoni thyroid hormone receptor 0.0142 0.0515 0.1008
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0368 0.1621
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0156
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0186 0.0448
Entamoeba histolytica acyl-coA synthetase, putative 0.0069 0.0207 0.0914
Brugia malayi Papain family cysteine protease containing protein 0.0124 0.0441 0.1061
Schistosoma mansoni adenoreceptor 0.0038 0.0072 0.0142
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0124 0.0441 0.0863
Brugia malayi cathepsin Z-like cysteine proteinase 0.0124 0.0441 0.1061
Giardia lamblia Cysteine protease 0.0124 0.0441 0.2774
Schistosoma mansoni hypothetical protein 0.021 0.0802 0.1571
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0076 0.0335
Schistosoma mansoni amine GPCR 0.0038 0.0072 0.0142
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0072 0.0072
Echinococcus multilocularis calpain A 0.0111 0.0383 0.0383
Plasmodium vivax serine-repeat antigen (SERA) 0.0124 0.0441 0.1943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0299 0.1182 0.5209
Loa Loa (eye worm) hypothetical protein 0.0069 0.0207 0.0499
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0072 0.0072
Echinococcus multilocularis serotonin receptor 0.0038 0.0072 0.0072
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0044 0.0193
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0174
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.007 0.0208 0.2013
Schistosoma mansoni hypothetical protein 0.0038 0.0072 0.0141
Loa Loa (eye worm) calpain 0.004 0.0082 0.0198
Echinococcus granulosus sex peptide receptor 0.0038 0.0072 0.0142
Echinococcus granulosus neuropeptide receptor 0.0038 0.0072 0.0142
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0503 0.2217
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0052 0.0133 0.032
Brugia malayi Dopamine receptor protein 1 0.0038 0.0072 0.0175
Schistosoma mansoni importin beta-1 0.0028 0.0031 0.0062
Onchocerca volvulus 0.0069 0.0207 0.0748
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0009 0.0039
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0072 0.0175
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0082 0.0198
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0178 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0186 0.0653
Entamoeba histolytica hypothetical protein 0.0035 0.006 0.0267
Schistosoma mansoni hypothetical protein 0.0122 0.0431 0.0843
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0368 0.0886
Onchocerca volvulus Peroxidase homolog 0.0064 0.0186 0.0653
Plasmodium vivax unspecified product 0.0124 0.0441 0.1943
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0368 0.072
Echinococcus multilocularis geminin 0.0165 0.0612 0.0612
Leishmania major cathepsin L-like protease 0.0555 0.2268 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0196 0.0744 0.1458
Echinococcus multilocularis calpain 0.004 0.0082 0.0082
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0072 0.0143
Mycobacterium ulcerans hypothetical protein 0.0155 0.057 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0124 0.0441 0.1943
Echinococcus multilocularis cathepsin L 0.0299 0.1182 0.1182
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0072 0.0072
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Brugia malayi cathepsin L precursor 0.0124 0.0441 0.1061
Brugia malayi cathepsin Z-like cysteine proteinase 0.0124 0.0441 0.1061
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0072 0.0175
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0111 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0061 0.0146
Trypanosoma cruzi cysteine peptidase, putative 0.0299 0.1182 0.2846
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0146
Echinococcus multilocularis peroxidasin 0.0064 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus granulosus g protein coupled receptor 0.0038 0.0072 0.0142
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0299 0.1182 0.2314
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0096 0.032 0.0772
Schistosoma mansoni chromobox protein 0.0069 0.0204 0.04
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0061 0.0267
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Onchocerca volvulus 0.0555 0.2268 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0043 0.0188
Echinococcus multilocularis enteropeptidase 0.0038 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Trypanosoma brucei calpain-like protein, putative 0.004 0.0082 0.0362
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Brugia malayi Papain family cysteine protease containing protein 0.0555 0.2268 0.5463
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0133 0.1417
Brugia malayi cathepsin B-like cysteine proteinase 0.0998 0.4152 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni Mername-AA248 (C02 family) 0.004 0.0082 0.0161
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0072 0.0072
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0072 0.0072
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0072 0.0175
Giardia lamblia Cathepsin B precursor 0.0395 0.1588 1
Echinococcus multilocularis calpain family protein 1, d 0.0078 0.0244 0.0244
Brugia malayi Trypsin family protein 0.0038 0.0072 0.0174
Brugia malayi Dopamine receptor 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0146
Brugia malayi RNA, U transporter 1 0.008 0.0251 0.0605
Onchocerca volvulus Cathepsin L homolog 0.0555 0.2268 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0133 0.032
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0083 0.0264 0.0636
Toxoplasma gondii cathepsin CPC2 0.0124 0.0441 0.1943
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0146
Schistosoma mansoni amine GPCR 0.0038 0.0072 0.0142
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0072 0.0142
Echinococcus multilocularis glycoprotein Antigen 5 0.0038 0.0072 0.0072
Echinococcus multilocularis calpain 7 (C02 family) 0.004 0.0082 0.0082
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0186 0.0448
Brugia malayi cathepsin F-like cysteine proteinase 0.0174 0.0653 0.1573
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni calpain (C02 family) 0.004 0.0082 0.0161
Brugia malayi Cathepsin L-like precursor 0.0174 0.0653 0.1573
Schistosoma mansoni hypothetical protein 0.0038 0.0072 0.0142
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.006 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0072 0.0142
Trichomonas vaginalis esterase, putative 0.0035 0.0061 0.0267
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0124 0.0441 0.1943
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0035 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0072 0.0142
Brugia malayi calpain 5 0.0028 0.0031 0.0075
Leishmania major cysteine peptidase A (CPA) 0.0555 0.2268 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0035 0.0156
Entamoeba histolytica protein kinase, putative 0.0028 0.0031 0.0137
Echinococcus multilocularis protein dispatched 1 0.0094 0.0314 0.0314
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0003 0.0006
Leishmania major importin beta-1 subunit, putative 0.0023 0.0009 0.0039
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0072 0.0072
Brugia malayi latrophilin 2 splice variant baaae 0.0135 0.0485 0.1169
Giardia lamblia Cathepsin B precursor 0.0124 0.0441 0.2774
Entamoeba histolytica cysteine proteinase, putative 0.0299 0.1182 0.5209
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0186 0.0448
Schistosoma mansoni hypothetical protein 0.0038 0.0072 0.0142
Brugia malayi AKH receptor 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0124 0.0441 0.1943
Trypanosoma brucei calpain-like protein, putative 0.004 0.0082 0.0362
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0362
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni hypothetical protein 0.0299 0.1184 0.2319
Brugia malayi Dopamine receptor protein 2 0.0038 0.0072 0.0175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0072 0.0142
Brugia malayi hypothetical protein 0.0038 0.0072 0.0174
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0178 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0441 0.1943
Schistosoma mansoni chromobox protein 0.0069 0.0204 0.04
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi Papain family cysteine protease containing protein 0.0299 0.1182 0.2846
Giardia lamblia Cathepsin L-like protease 0.0124 0.0441 0.2774
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0044 0.0105
Echinococcus multilocularis cathepsin b 0.0998 0.4152 0.4152
Onchocerca volvulus 0.0038 0.0072 0.0143
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0072 0.0175
Toxoplasma gondii cathepsin CPC1 0.0124 0.0441 0.1943
Loa Loa (eye worm) beta-lactamase 0.0035 0.0061 0.0146
Entamoeba histolytica acyl-CoA synthetase, putative 0.0069 0.0207 0.0914
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0072 0.0142
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0178 0.0428
Entamoeba histolytica hypothetical protein 0.0035 0.006 0.0267
Trypanosoma brucei proteasome subunit beta type-5, putative 0.007 0.0208 0.0917
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0124 0.0441 0.1943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0186 0.0448
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0368 0.0886
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0106 0.0362 0.0873
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Schistosoma mansoni hypothetical protein 0.0035 0.006 0.0118
Schistosoma mansoni neuropeptide receptor 0.0038 0.0072 0.0142
Brugia malayi isocitrate dehydrogenase 0.0031 0.0044 0.0105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0555 0.2268 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0043 0.0188
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Plasmodium falciparum serine repeat antigen 7 0.0124 0.0441 0.1943
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0124 0.0441 0.1943
Echinococcus multilocularis cathepsin L 0.0124 0.0441 0.0441
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0106 0.0362 0.0709
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Echinococcus multilocularis calpain 5 0.004 0.0082 0.0082
Loa Loa (eye worm) cysteine protease 0.0555 0.2268 0.5463
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0124 0.0441 0.0863
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.0751 0.1808
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0441 0.1943
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0072 0.0175
Echinococcus granulosus cathepsin L 0.0299 0.1182 0.2314
Brugia malayi Cathepsin L-like precursor 0.0555 0.2268 0.5463
Loa Loa (eye worm) fibroinase 0.0555 0.2268 0.5463
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0088 0.0211
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.116 0.2794
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0124 0.0441 0.1943
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0043 0.0188
Entamoeba histolytica cysteine protease, putative 0.0124 0.0441 0.1943
Brugia malayi Serotonin receptor 0.0038 0.0072 0.0175
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Echinococcus granulosus chromobox protein 1 0.0069 0.0204 0.04
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0124 0.0441 0.2774
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0186 0.0448
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0368 0.072
Echinococcus granulosus enteropeptidase 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0066 0.0193 0.0464
Onchocerca volvulus 0.0038 0.0072 0.0143
Schistosoma mansoni biogenic amine receptor 0.0038 0.0072 0.0142
Echinococcus granulosus geminin 0.0165 0.0612 0.1199
Echinococcus granulosus calpain 7 C02 family 0.004 0.0082 0.0161
Schistosoma mansoni hypothetical protein 0.008 0.0251 0.0492
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0124 0.0441 0.2774
Onchocerca volvulus 0.0555 0.2268 1
Brugia malayi Cathepsin L-like precursor 0.0555 0.2268 0.5463
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0072 0.0072
Echinococcus granulosus proteasome prosome macropain 0.007 0.0208 0.0407
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0038 0.0072 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0124 0.0441 0.1061
Trypanosoma cruzi cysteine proteinase, putative 0.0299 0.1182 0.2846
Brugia malayi hypothetical protein 0.0038 0.0072 0.0175
Schistosoma mansoni hypothetical protein 0.0165 0.0612 0.1199
Plasmodium falciparum acyl-CoA synthetase 0.0052 0.0133 0.0585
Echinococcus granulosus cathepsin l cysteine peptidase 0.0555 0.2268 0.4442
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0072 0.0142
Echinococcus multilocularis GPCR, family 2 0.0062 0.0178 0.0178
Onchocerca volvulus 0.0038 0.0072 0.0141
Brugia malayi Proteasome A-type and B-type family protein 0.007 0.0208 0.0501
Onchocerca volvulus 0.0035 0.0061 0.009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0082 0.0198
Echinococcus multilocularis expressed conserved protein 0.0181 0.0682 0.0682
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.007 0.0208 0.0501
Echinococcus granulosus expressed conserved protein 0.0181 0.0682 0.1335
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0061 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.038 0.1527 0.6734
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Schistosoma mansoni calpain C (C02 family) 0.004 0.0082 0.0161
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0003 0.0006
Brugia malayi Cathepsin L-like precursor 0.0555 0.2268 0.5463
Plasmodium falciparum serine repeat antigen 4 0.0124 0.0441 0.1943
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0044
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Loa Loa (eye worm) hypothetical protein 0.0064 0.0186 0.0448
Plasmodium vivax cysteine repeat modular protein 1, putative 0.021 0.0802 0.3538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Plasmodium falciparum serine repeat antigen 2 0.0124 0.0441 0.1943
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0156
Schistosoma mansoni cathepsin S (C01 family) 0.0124 0.0441 0.0863
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Toxoplasma gondii kringle domain-containing protein 0.021 0.0802 0.3538
Loa Loa (eye worm) hypothetical protein 0.0062 0.0178 0.0428
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Brugia malayi hypothetical protein 0.0035 0.006 0.0146
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0072 0.0143
Schistosoma mansoni cercarial elastase (S01 family) 0.0038 0.0072 0.0141
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0368 0.1621
Brugia malayi 6-phosphofructokinase 0.0107 0.0368 0.0886
Brugia malayi Cathepsin L-like precursor 0.0555 0.2268 0.5463
Trypanosoma cruzi calpain cysteine peptidase, putative 0.004 0.0082 0.0198
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.007 0.0208 0.0917
Echinococcus granulosus calpain A 0.004 0.0082 0.0161
Echinococcus granulosus g protein coupled receptor 0.0038 0.0072 0.0142
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi CXXC zinc finger family protein 0.0086 0.0277 0.0667
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0175
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0072 0.0175
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0072 0.0072
Brugia malayi follicle stimulating hormone receptor 0.0038 0.0072 0.0175
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0124 0.0441 0.1943
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0555 0.2268 1
Plasmodium vivax proteasome subunit beta type-5, putative 0.007 0.0208 0.0917
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0555 0.2268 1
Onchocerca volvulus 0.0555 0.2268 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0052 0.0133 0.0585
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0061 0.0146
Brugia malayi Trypsin family protein 0.0038 0.0072 0.0174
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0072 0.0142
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0207 0.2004
Entamoeba histolytica cysteine protease, putative 0.0299 0.1182 0.5209
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0061 0.0206
Echinococcus multilocularis gamma secretase subunit aph 1 0.0728 0.3003 0.3003
Trypanosoma brucei kinesin, putative 0.0028 0.0031 0.0137

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 11.5 uM Inhibitory activity against L 1210 cell proliferation ChEMBL. 12408717

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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