Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.056 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0505 | 0.8701 | 0.8254 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0241 | 0.2563 | 0.2563 |
Echinococcus granulosus | histone deacetylase 6 | 0.0505 | 0.8701 | 0.8619 |
Schistosoma mansoni | histone deacetylase | 0.056 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.056 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.056 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.056 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0156 | 0.0597 | 0.0597 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0519 | 0.9038 | 0.8813 |
Entamoeba histolytica | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Brugia malayi | Histone deacetylase family protein | 0.0505 | 0.8701 | 0.8254 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0505 | 0.8701 | 0.8701 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0312 | 0.4209 | 0.286 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.3094 | 0.0715 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0241 | 0.2563 | 0.083 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0287 | 0.3641 | 0.3238 |
Trichomonas vaginalis | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0312 | 0.4209 | 0.2213 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0312 | 0.4209 | 0.2213 |
Trichomonas vaginalis | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.056 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.0505 | 0.8701 | 0.7758 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.056 | 1 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0505 | 0.8701 | 0.8254 |
Echinococcus multilocularis | histone deacetylase | 0.0505 | 0.8701 | 0.8701 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0241 | 0.2563 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.056 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.056 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.056 | 1 | 1 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0312 | 0.4209 | 0.2213 |
Trypanosoma brucei | histone deacetylase 3 | 0.0505 | 0.8701 | 0.8254 |
Trypanosoma brucei | histone deacetylase 4 | 0.0505 | 0.8701 | 0.8254 |
Schistosoma mansoni | histone deacetylase | 0.056 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0312 | 0.4209 | 0.2213 |
Echinococcus granulosus | histone deacetylase 3 | 0.056 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0505 | 0.8701 | 0.8701 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0505 | 0.8701 | 0.8701 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0312 | 0.4209 | 0.4209 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0505 | 0.8701 | 0.8254 |
Echinococcus granulosus | histone deacetylase | 0.0505 | 0.8701 | 0.8619 |
Giardia lamblia | Histone deacetylase | 0.056 | 1 | 0.5 |
Echinococcus granulosus | histone deacetylase 8 | 0.0241 | 0.2563 | 0.2091 |
Echinococcus multilocularis | histone deacetylase 3 | 0.056 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0312 | 0.4209 | 0.3841 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0175 | 0.1035 | 0.1035 |
Trichomonas vaginalis | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Echinococcus granulosus | histone deacetylase 7 | 0.0505 | 0.8701 | 0.8619 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0312 | 0.4209 | 0.2213 |
Loa Loa (eye worm) | histone deacetylase | 0.0505 | 0.8701 | 0.8254 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0519 | 0.9038 | 0.9038 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.056 | 1 | 1 |
Plasmodium falciparum | histone deacetylase 1 | 0.056 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 1 | 0.056 | 1 | 1 |
Plasmodium vivax | histone deacetylase, putative | 0.0505 | 0.8701 | 0.8254 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.3431 | 0.1167 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0287 | 0.3641 | 0.3641 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.056 | 1 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.056 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.0505 | 0.8701 | 0.7758 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0175 | 0.1035 | 0.0466 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0505 | 0.8701 | 0.8254 |
Brugia malayi | Histone deacetylase family protein | 0.0505 | 0.8701 | 0.8254 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.056 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0505 | 0.8701 | 0.8254 |
Echinococcus granulosus | histone deacetylase 6 | 0.0505 | 0.8701 | 0.8619 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.056 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0505 | 0.8701 | 0.8254 |
Trichomonas vaginalis | histone deacetylase, putative | 0.056 | 1 | 0.5 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0312 | 0.4209 | 0.2213 |
Echinococcus multilocularis | histone deacetylase 1 | 0.056 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.056 | 1 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0519 | 0.9038 | 0.8977 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0241 | 0.2563 | 0.083 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0505 | 0.8701 | 0.8399 |
Trypanosoma brucei | histone deacetylase, putative | 0.0505 | 0.8701 | 0.8254 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0505 | 0.8701 | 0.8399 |
Leishmania major | histone deacetylase, putative | 0.056 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 0 | Compound was tested in vivo for inhibition of Monoamine oxidase (MAO); Active | ChEMBL. | 3959029 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.