Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Loa Loa (eye worm) | hypothetical protein | 0.0662 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Brugia malayi | Papain family cysteine protease containing protein | 0.017 | 0.1455 | 0.1287 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0132 | 0.0791 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0255 | 0.2928 | 0.7433 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0216 | 0.2246 | 0.2246 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.0082 | 0.008 |
Loa Loa (eye worm) | ctsf protein | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | cysteine protease, putative | 0.017 | 0.1455 | 0.1455 |
Plasmodium vivax | vivapain-2 | 0.0313 | 0.3939 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.2703 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.017 | 0.1455 | 0.1455 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0313 | 0.3939 | 0.3938 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.017 | 0.1455 | 0.2109 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0098 | 0.0193 | 0.0193 |
Echinococcus multilocularis | cathepsin L | 0.017 | 0.1455 | 0.1454 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Echinococcus granulosus | cysteine protease | 0.017 | 0.1455 | 0.1454 |
Onchocerca volvulus | Cathepsin L homolog | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0098 | 0.0193 | 0.0192 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Echinococcus granulosus | cathepsin b | 0.0662 | 1 | 1 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.0082 | 0.008 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.017 | 0.1455 | 0.1455 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0313 | 0.3939 | 0.3939 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0216 | 0.2246 | 0.2093 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0132 | 0.0791 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0255 | 0.2928 | 0.2789 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.017 | 0.1455 | 0.1455 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.017 | 0.1455 | 0.3695 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0662 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0313 | 0.3939 | 0.3938 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.017 | 0.1455 | 0.1455 |
Echinococcus granulosus | cathepsin l1 | 0.0216 | 0.2246 | 0.2245 |
Echinococcus multilocularis | cathepsin b | 0.0662 | 1 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Echinococcus granulosus | cathepsin b | 0.0662 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0313 | 0.3939 | 0.382 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Leishmania major | cysteine peptidase A (CPA) | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0132 | 0.0791 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0255 | 0.2928 | 0.7434 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.061 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Echinococcus multilocularis | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0216 | 0.2246 | 0.5699 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.017 | 0.1455 | 0.3693 |
Brugia malayi | Papain family cysteine protease containing protein | 0.017 | 0.1455 | 0.1287 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Brugia malayi | Cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Echinococcus multilocularis | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0662 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Toxoplasma gondii | cathepsin B | 0.0255 | 0.2928 | 0.6788 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Echinococcus granulosus | cathepsin L | 0.017 | 0.1455 | 0.1454 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.017 | 0.1455 | 0.1454 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Onchocerca volvulus | Cathepsin L homolog | 0.0313 | 0.3939 | 1 |
Plasmodium vivax | vivapain-3 | 0.017 | 0.1455 | 0.3369 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0255 | 0.2928 | 0.2927 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0313 | 0.3939 | 0.382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Plasmodium vivax | vivapain-2 | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0098 | 0.0193 | 0.0193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0216 | 0.2246 | 0.5699 |
Echinococcus multilocularis | cathepsin b | 0.0662 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0216 | 0.2246 | 0.462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.017 | 0.1455 | 0.3695 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.017 | 0.1455 | 0.3693 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0255 | 0.2928 | 0.7434 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.1597 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Entamoeba histolytica | cysteine proteinase 2 | 0.017 | 0.1455 | 0.2109 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0313 | 0.3939 | 0.3938 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Plasmodium vivax | vivapain-1 | 0.017 | 0.1455 | 0.3369 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.5 |
Plasmodium vivax | unspecified product | 0.017 | 0.1455 | 0.3369 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Brugia malayi | cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0255 | 0.2928 | 0.2928 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Entamoeba histolytica | cysteine protease, putative | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0216 | 0.2246 | 0.2093 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0132 | 0.0791 | 0.2009 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ILS (functional) | = 0 % | Percent increase in median life span of BDF1 mice with P-388 leukemia at dose 200 mg/kg administered intraperitoneally | ChEMBL. | 6806475 |
ILS (functional) | = 0 % | Percent increase in median life span of BDF1 mice with B-16 melanoma at dose 50 mg/kg administered intraperitoneally | ChEMBL. | 6806475 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.