Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0956 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0592 | 0.5073 | 0.5073 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0592 | 0.5073 | 0.5073 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0956 | 1 | 1 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0956 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0592 | 0.5073 | 0.5073 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0956 | 1 | 1 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0956 | 1 | 1 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0956 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0956 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0956 | 1 | 1 |
Onchocerca volvulus | 0.0216 | 0 | 0.5 | |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0956 | 1 | 0.5 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0956 | 1 | 1 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0956 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0956 | 1 | 1 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0956 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0956 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0956 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0956 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0592 | 0.5073 | 0.5073 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0956 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0956 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative uptake (functional) | = 1.04 | In vitro relative vinblastin uptake into P388/s (murine leukaemia) cells following 10 uM treatment. | ChEMBL. | 8544183 |
Relative uptake (functional) | = 1.14 | In vitro relative vinblastin uptake into P388/ADR (murine leukaemia/multidrug resistant) cells following 10 uM treatment. | ChEMBL. | 8544183 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.