TDR Targets

Basic information

Technical information

TDR Targets ID: 257142
Name: 3-(pyrrolidin-1-ylmethyl)pyridine
MW: 162.232 | Formula: C10H14N2
H donors: 0 H acceptors: 1 LogP: 1.18 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: c1ccc(cn1)CN1CCCC1
InChi: 1S/C10H14N2/c1-2-7-12(6-1)9-10-4-3-5-11-8-10/h3-5,8H,1-2,6-7,9H2
InChiKey: YFCWBKBNFCDPDF-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-(1-pyrrolidinylmethyl)pyridine
3-(pyrrolidinomethyl)pyridine
N-(3-pyridylmethyl)pyrrolidine
370-09-2
AIDS-133018
(3-Pyridylmethyl)pyrrolidine
3-Pyr-Me-pyrrolidine
Pyridine, 3-(1-pyrrolidinylmethyl)-
AIDS133018
NSC628102

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	solute carrier family 6 (neurotransmitter transporter), member 4	Starlite/ChEMBL	References
Homo sapiens	cholinergic receptor, nicotinic, alpha 4 (neuronal)	Starlite/ChEMBL	References
Homo sapiens	cholinergic receptor, nicotinic, beta 2 (neuronal)		References
Musca domestica	Nicotinic acetylcholine receptor alpha 5 subunit	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma japonicum	ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Treponema pallidum	sodium- and chloride- dependent transporter	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	IPR006201,Neurotransmitter-gated ion-channel;IPR006029,Neurotransmitter-gated ion-channel transmembrane region,domain-containing	Get druggable targets OG5_130932	All targets in OG5_130932
Schistosoma japonicum	Sodium-dependent dopamine transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	Sodium-dependent dopamine transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Echinococcus granulosus	serotonin transporter	Get druggable targets OG5_128364	All targets in OG5_128364
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_130932	All targets in OG5_130932
Loa Loa (eye worm)	serotonin transporter b	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma mansoni	norepinephrine/norepinephrine transporter	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	ko:K04809 cholinergic receptor, nicotinic, alpha 7, putative	Get druggable targets OG5_130932	All targets in OG5_130932
Onchocerca volvulus	Putative nachr subunit	Get druggable targets OG5_128160	All targets in OG5_128160
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_130932	All targets in OG5_130932
Onchocerca volvulus		Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	IPR000175,Sodium:neurotransmitter symporter,domain-containing	Get druggable targets OG5_128364	All targets in OG5_128364
Brugia malayi	Sodium:neurotransmitter symporter family protein	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	Neuronal acetylcholine receptor subunit alpha-7 precursor, putative	Get druggable targets OG5_130932	All targets in OG5_130932
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	Get druggable targets OG5_128160	All targets in OG5_128160
Echinococcus multilocularis	serotonin transporter	Get druggable targets OG5_128364	All targets in OG5_128364
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	Neuronal acetylcholine receptor subunit alpha-7 precursor, putative	Get druggable targets OG5_130932	All targets in OG5_130932
Schistosoma japonicum	Sodium-dependent dopamine transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128364	All targets in OG5_128364
Loa Loa (eye worm)	solute carrier family 6 member 4	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	Neuronal acetylcholine receptor subunit alpha-7 precursor, putative	Get druggable targets OG5_130932	All targets in OG5_130932
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_130932	All targets in OG5_130932
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128160	All targets in OG5_128160
Brugia malayi	Cation transporter family protein	Get druggable targets OG5_130932	All targets in OG5_130932
Schistosoma japonicum	Sodium-dependent dopamine transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	Get druggable targets OG5_128160	All targets in OG5_128160
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	Get druggable targets OG5_128160	All targets in OG5_128160
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	Get druggable targets OG5_130932	All targets in OG5_130932
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	Get druggable targets OG5_128160	All targets in OG5_128160
Onchocerca volvulus		Get druggable targets OG5_130932	All targets in OG5_130932
Schistosoma mansoni	sodium/chloride dependent transporter	Get druggable targets OG5_128364	All targets in OG5_128364
Onchocerca volvulus		Get druggable targets OG5_130932	All targets in OG5_130932
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	Get druggable targets OG5_130932	All targets in OG5_130932
Schistosoma japonicum	Sodium-dependent dopamine transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Onchocerca volvulus		Get druggable targets OG5_130932	All targets in OG5_130932
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	Get druggable targets OG5_128160	All targets in OG5_128160
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	Get druggable targets OG5_128160	All targets in OG5_128160
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	Get druggable targets OG5_128160	All targets in OG5_128160
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	Sodium-dependent noradrenaline transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Schistosoma japonicum	Sodium-dependent dopamine transporter, putative	Get druggable targets OG5_128364	All targets in OG5_128364
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	Get druggable targets OG5_128160	All targets in OG5_128160
Loa Loa (eye worm)	norepinephrine transporter	Get druggable targets OG5_128364	All targets in OG5_128364

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	Sodium:neurotransmitter symporter family protein	solute carrier family 6 (neurotransmitter transporter), member 4	630 aa	574 aa	31.5 %
Brugia malayi	Cation transporter family protein	cholinergic receptor, nicotinic, beta 2 (neuronal)	502 aa	482 aa	32.4 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus granulosus	tyrosine protein kinase Blk	0.0295	0.1276	0.1276
Schistosoma mansoni	signal transduction protein lnk-related	0.0033	0.0004	0.0004
Echinococcus multilocularis		0.0033	0.0004	0.0004
Schistosoma mansoni	tyrosine kinase	0.0327	0.143	0.143
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0073	0.0199	0.0199
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0033	0.0004	0.0004
Echinococcus granulosus	SH2 motif	0.0033	0.0004	0.0004
Schistosoma mansoni	SH2A	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0341	0.0341
Schistosoma mansoni	tyrosine kinase	0.0042	0.0048	0.0048
Echinococcus multilocularis	protein kinase shaggy	0.2095	1	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0479	0.0479
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0327	0.143	0.143
Onchocerca volvulus		0.0042	0.0048	0.0048
Leishmania major	4-coumarate:coa ligase-like protein	0.0102	0.0341	0.0341
Onchocerca volvulus		0.0102	0.0341	0.0341
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0042	0.0048	0.0048
Echinococcus granulosus	tyrosine protein kinase Srms	0.0042	0.0048	0.0048
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0045	0.0064	0.0064
Leishmania major	4-coumarate:coa ligase-like protein	0.0102	0.0341	0.0341
Mycobacterium ulcerans	acyl-CoA synthetase	0.0102	0.0341	0.0316
Brugia malayi	STAT protein, DNA binding domain containing protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0045	0.0064	0.0064
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0045	0.0064	0.0064
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0327	0.143	0.143
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0033	0.0004	0.0004
Brugia malayi	AMP-binding enzyme family protein	0.0102	0.0341	0.0341
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0158	0.0158
Brugia malayi	Protein kinase domain containing protein	0.0042	0.0048	0.0048
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0327	0.143	0.143
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Onchocerca volvulus	Putative nachr subunit	0.0131	0.0479	0.0479
Schistosoma mansoni	shc transforming protein	0.0033	0.0004	0.0004
Onchocerca volvulus		0.0042	0.0048	0.0048
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Echinococcus multilocularis	tensin	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.011	0.0378	0.0378
Schistosoma mansoni	growth factor receptor-bound protein	0.0065	0.0158	0.0158
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0033	0.0004	0.0004
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0102	0.0341	0.0316
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0045	0.0064	0.0064
Loa Loa (eye worm)	ACC-1 protein	0.0045	0.0064	0.0064
Brugia malayi	Variant SH3 domain containing protein	0.0065	0.0158	0.0158
Brugia malayi	AMP-binding enzyme family protein	0.0102	0.0341	0.0341
Echinococcus granulosus	protein kinase shaggy	0.2095	1	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	TK/ABL protein kinase	0.0042	0.0048	0.0048
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0065	0.0158	0.0158
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0053	0.0101	0.0101
Echinococcus granulosus	tyrosine kinase	0.0295	0.1276	0.1276
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0045	0.0064	0.0064
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Entamoeba histolytica	protein kinase domain containing protein	0.2095	1	1
Leishmania major	glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270	0.2095	1	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0262	0.1117	0.1117
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0033	0.0004	0.0004
Giardia lamblia	Kinase, CMGC GSK	0.2095	1	0.5
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0131	0.0479	0.0479
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0045	0.0064	0.0064
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Onchocerca volvulus		0.0131	0.0479	0.0479
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Brugia malayi	SH2 domain containing protein	0.0042	0.0048	0.0048
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0033	0.0004	0.0004
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0102	0.0341	0.0316
Echinococcus granulosus	glycine receptor subunit beta	0.0045	0.0064	0.0064
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0074	0.0203	0.0203
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0295	0.1276	0.1276
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Brugia malayi	Protein kinase domain containing protein	0.0042	0.0048	0.0048
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Brugia malayi	excitatory GABA receptor EXP-1A	0.0045	0.0064	0.0064
Brugia malayi	protein-tyrosine kinase	0.0295	0.1276	0.1276
Entamoeba histolytica	SH2 domain containing protein	0.0033	0.0004	0.0004
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0327	0.143	0.143
Onchocerca volvulus		0.0033	0.0004	0.0004
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0131	0.0479	0.0479
Schistosoma mansoni	sodium/chloride dependent transporter	0.0032	0.0003	0.0003
Onchocerca volvulus		0.0131	0.0479	0.0479
Schistosoma mansoni	suppressor of cytokine signaling	0.0033	0.0004	0.0004
Echinococcus multilocularis	NCK adaptor protein	0.0065	0.0158	0.0158
Echinococcus granulosus	hypothetical protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0074	0.0203	0.0203
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0045	0.0064	0.0064
Schistosoma mansoni	tyrosine kinase	0.0327	0.143	0.143
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0074	0.0203	0.0203
Loa Loa (eye worm)	SRC-1	0.0327	0.143	0.143
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Onchocerca volvulus		0.0042	0.0048	0.0048
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0045	0.0064	0.0064
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0042	0.0048	0.0048
Onchocerca volvulus		0.0045	0.0064	0.0064
Echinococcus multilocularis	SH2 motif	0.0033	0.0004	0.0004
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0033	0.0004	0.0004
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0042	0.0048	0.0048
Trypanosoma cruzi	glycogen synthase kinase 3, putative	0.2095	1	1
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0045	0.0064	0.0064
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0074	0.0203	0.0203
Brugia malayi	hypothetical protein	0.0042	0.0048	0.0048
Plasmodium falciparum	glycogen synthase kinase 3	0.2095	1	1
Brugia malayi	Protein kinase domain containing protein	0.0042	0.0048	0.0048
Echinococcus granulosus	expressed conserved protein	0.0033	0.0004	0.0004
Brugia malayi	Protein kinase domain containing protein	0.0042	0.0048	0.0048
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0065	0.0158	0.0158
Brugia malayi	Sex muscle abnormal protein 5	0.0065	0.0158	0.0158
Echinococcus multilocularis	tensin	0.0033	0.0004	0.0004
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0045	0.0064	0.0064
Echinococcus granulosus	SH2 motif	0.0033	0.0004	0.0004
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0076	0.0216	0.0051
Loa Loa (eye worm)	SH2 domain-containing protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0033	0.0004	0.0004
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0045	0.0064	0.0064
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus granulosus	glycogen synthase kinase 3 beta	0.2095	1	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0045	0.0064	0.0064
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0033	0.0004	0.0004
Brugia malayi	SRC-1	0.0327	0.143	0.143
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0199	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0216	0.0216
Onchocerca volvulus		0.0073	0.0199	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0048	0.0048
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Onchocerca volvulus		0.0052	0.0097	0.0097
Echinococcus multilocularis	SH2 motif	0.0033	0.0004	0.0004
Schistosoma mansoni	tensin-related	0.0033	0.0004	0.0004
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0102	0.0341	0.0341
Echinococcus multilocularis	c src tyrosine kinase	0.0074	0.0203	0.0203
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0102	0.0341	0.0366
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0045	0.0064	0.0064
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0295	0.1276	0.1276
Brugia malayi	Variant SH3 domain containing protein	0.0065	0.0158	0.0158
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0045	0.0064	0.0064
Toxoplasma gondii	cell-cycle-associated protein kinase GSK, putative	0.2095	1	0.5
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0045	0.0064	0.0064
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0131	0.0479	0.0479
Schistosoma mansoni	tensin	0.0033	0.0004	0.0004
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0045	0.0064	0.0064
Schistosoma mansoni	hypothetical protein	0.0033	0.0004	0.0004
Schistosoma mansoni	glycogen synthase kinase 3-related (gsk3) (cmgc group III)	0.2095	1	1
Trichomonas vaginalis	CMGC family protein kinase	0.2095	1	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0327	0.143	0.143
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0479	0.0479
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Onchocerca volvulus		0.0045	0.0064	0.0064
Mycobacterium tuberculosis	Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase)	0.0893	0.4175	1
Loa Loa (eye worm)	norepinephrine transporter	0.0073	0.0199	0.0199
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0045	0.0064	0.0064
Echinococcus multilocularis	glycogen synthase kinase 3 beta	0.2095	1	1
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0033	0.0004	0.0004
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	nAChR subunit	0.0045	0.0064	0.0064
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0131	0.0479	0.0479
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0045	0.0064	0.0064
Leishmania major	4-coumarate:coa ligase-like protein	0.0102	0.0341	0.0341
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0045	0.0064	0.0064
Echinococcus multilocularis	signal transduction protein lnk realted	0.0033	0.0004	0.0004
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Brugia malayi	Cation transporter family protein	0.0045	0.0064	0.0064
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0045	0.0064	0.0064
Treponema pallidum	sodium- and chloride- dependent transporter	0.0073	0.0199	0.5
Loa Loa (eye worm)	serotonin transporter b	0.0073	0.0199	0.0199
Schistosoma mansoni	tensin	0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0327	0.143	0.143
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0341	0.0341
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0479	0.0479
Entamoeba histolytica	acyl-coA synthetase, putative	0.0102	0.0341	0.0341
Echinococcus multilocularis	N chimaerin	0.0033	0.0004	0.0004
Echinococcus multilocularis	serotonin transporter	0.0073	0.0199	0.0199
Onchocerca volvulus		0.0033	0.0004	0.0004
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0033	0.0004	0.0004
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Brugia malayi	AMP-binding enzyme family protein	0.0102	0.0341	0.0341
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Loa Loa (eye worm)	LGC-31 protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0216	0.0216
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0199	0.0199
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0327	0.143	0.143
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0327	0.143	0.143
Onchocerca volvulus		0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Schistosoma mansoni	adapter molecule crk	0.0065	0.0158	0.0158
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0033	0.0004	0.0004
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Schistosoma mansoni	tensin-related	0.0033	0.0004	0.0004
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0045	0.0064	0.0064
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0033	0.0004	0.0004
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0045	0.0064	0.0064
Loa Loa (eye worm)	ACC-1 protein	0.0045	0.0064	0.0064
Entamoeba histolytica	protein kinase domain containing protein	0.2095	1	1
Brugia malayi	tRNA modification GTPase TrmE family protein	0.0033	0.0004	0.0004
Mycobacterium ulcerans	acyl-CoA synthetase	0.0102	0.0341	0.0316
Loa Loa (eye worm)	TK protein kinase	0.0295	0.1276	0.1276
Giardia lamblia	Kinase, CMGC GSK	0.2095	1	0.5
Echinococcus multilocularis	SHC transforming protein 3	0.0033	0.0004	0.0004
Onchocerca volvulus		0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine kinase	0.0042	0.0048	0.0048
Brugia malayi	SH2 domain containing protein	0.0042	0.0048	0.0048
Brugia malayi	cytokine inducible SH2-containing protein 5	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus granulosus	glycine receptor subunit beta	0.0045	0.0064	0.0064
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0327	0.143	0.143
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0131	0.0479	0.0479
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0131	0.0479	0.0479
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0102	0.0341	0.0366
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0045	0.0064	0.0064
Entamoeba histolytica	protein kinase, putative	0.0262	0.1117	0.1117
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0286	0.1231	0.1231
Brugia malayi	RhoGAP domain containing protein	0.0033	0.0004	0.0004
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0102	0.0341	0.0341
Loa Loa (eye worm)	solute carrier family 6 member 4	0.0073	0.0199	0.0199
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0033	0.0004	0.0004
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0102	0.0341	0.0316
Echinococcus multilocularis	SH2 domain containing protein 7	0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0042	0.0048	0.0048
Schistosoma mansoni	tyrosine kinase	0.0074	0.0203	0.0203
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0102	0.0341	0.5
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0045	0.0064	0.0064
Schistosoma mansoni	GTPase activating protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0065	0.0158	0.0158
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0076	0.0216	0.5
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0045	0.0064	0.0064
Schistosoma mansoni	sodium/chloride dependent transporter	0.0073	0.0199	0.0199
Mycobacterium ulcerans	acyl-CoA synthetase	0.0102	0.0341	0.0316
Brugia malayi	SH2 domain containing protein	0.0033	0.0004	0.0004
Schistosoma mansoni	suppressor of cytokine signaling	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Trypanosoma brucei	protein kinase, putative	0.2095	1	1
Brugia malayi	Protein kinase domain containing protein	0.0042	0.0048	0.0048
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Echinococcus granulosus	growth factor receptor bound protein 2	0.0065	0.0158	0.0158
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.0045	0.0064	0.0064
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0131	0.0479	0.0479
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0295	0.1276	0.1276
Onchocerca volvulus		0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0341	0.0341
Trichomonas vaginalis	CMGC family protein kinase	0.2095	1	1
Loa Loa (eye worm)	TK protein kinase	0.0262	0.1117	0.1117
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	SH2 domain-containing protein	0.0033	0.0004	0.0004
Echinococcus granulosus	signal transduction protein lnk realted	0.0033	0.0004	0.0004
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0033	0.0004	0.0004
Schistosoma mansoni	tensin	0.0033	0.0004	0.0004
Onchocerca volvulus		0.0131	0.0479	0.0479
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0327	0.143	0.143
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0065	0.0158	0.0158
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0045	0.0064	0.0064
Entamoeba histolytica	protein kinase, putative	0.2095	1	1
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0216	0.0216
Brugia malayi	Tensin	0.0033	0.0004	0.0004
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0073	0.0199	0.0199
Mycobacterium ulcerans	haloalkane dehalogenase	0.0893	0.4175	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0033	0.0004	0.0004
Echinococcus multilocularis	glycine receptor subunit beta	0.0045	0.0064	0.0064
Brugia malayi	Variant SH3 domain containing protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus multilocularis	glycine receptor subunit beta	0.0045	0.0064	0.0064
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0033	0.0004	0.0004
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0042	0.0048	0.0048
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0347	0.1528	0.1528
Schistosoma mansoni	tyrosine kinase	0.0042	0.0048	0.0048
Brugia malayi	Variant SH3 domain containing protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Brugia malayi	Cation transporter family protein	0.0131	0.0479	0.0479
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0045	0.0064	0.0064
Echinococcus granulosus	tyrosine kinase	0.0042	0.0048	0.0048
Schistosoma mansoni	growth factor receptor-bound protein	0.0065	0.0158	0.0158
Echinococcus granulosus	NCK adaptor protein	0.0065	0.0158	0.0158
Entamoeba histolytica	protein kinase, putative	0.0053	0.0101	0.0101
Echinococcus granulosus	c src tyrosine kinase	0.0074	0.0203	0.0203
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0045	0.0064	0.0064
Onchocerca volvulus		0.0042	0.0048	0.0048
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Schistosoma mansoni	hypothetical protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0033	0.0004	0.0004
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0033	0.0004	0.0004
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0102	0.0341	0.5
Mycobacterium ulcerans	hypothetical protein	0.0102	0.0341	0.0316
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0131	0.0479	0.0479
Echinococcus granulosus	N chimaerin	0.0033	0.0004	0.0004
Loa Loa (eye worm)	SH2 domain-containing protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0327	0.143	0.143
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0033	0.0004	0.0004
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0033	0.0004	0.0004
Echinococcus granulosus	serotonin transporter	0.0073	0.0199	0.0199
Schistosoma mansoni	tyrosine kinase	0.0074	0.0203	0.0203
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Brugia malayi	Tyrosine-protein kinase abl-1	0.0074	0.0203	0.0203
Echinococcus granulosus	tyrosine protein kinase shark	0.0042	0.0048	0.0048
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0295	0.1276	0.1276
Schistosoma mansoni	vav2	0.0033	0.0004	0.0004
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0327	0.143	0.143
Brugia malayi	Cation transporter family protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0033	0.0004	0.0004
Schistosoma mansoni	nAChR subunit	0.0045	0.0064	0.0064
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0327	0.143	0.143
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0045	0.0064	0.0064
Loa Loa (eye worm)	STAT protein	0.0033	0.0004	0.0004
Schistosoma mansoni	serine/threonine protein kinase	0.0041	0.0044	0.0044
Onchocerca volvulus		0.0042	0.0048	0.0048
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0286	0.1231	0.1231
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0045	0.0064	0.0064
Onchocerca volvulus		0.0042	0.0048	0.0048
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0102	0.0341	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus granulosus	SH2 domain containing protein 7	0.0033	0.0004	0.0004
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0045	0.0064	0.0064
Brugia malayi	hypothetical protein	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus granulosus	SHC transforming protein 3	0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase shark	0.0042	0.0048	0.0048
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0216	0.0216
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0327	0.143	0.143
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0131	0.0479	0.0479
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0033	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus granulosus	tyrosine protein kinase HCK	0.0262	0.1117	0.1117
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0216	0.0216
Onchocerca volvulus		0.0033	0.0004	0.0004
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0045	0.0064	0.0064
Onchocerca volvulus		0.2095	1	1
Onchocerca volvulus		0.0033	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0327	0.143	0.143
Schistosoma mansoni	nck2/grb4	0.0065	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0199	0.0199
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0131	0.0479	0.0479
Loa Loa (eye worm)	TK/FER protein kinase	0.0042	0.0048	0.0048
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0064	0.0064
Echinococcus multilocularis	SH2 motif	0.0033	0.0004	0.0004
Echinococcus granulosus	tensin	0.0033	0.0004	0.0004
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0045	0.0064	0.0064
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0327	0.143	0.143
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0045	0.0064	0.0064
Echinococcus granulosus	nAChR subunit	0.0045	0.0064	0.0064
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.2095	1	1
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.2095	1	1
Plasmodium vivax	glycogen synthase kinase 3, putative	0.2095	1	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 1.4 mM	Inhibition of Musca domestica (house fly) acetylcholinesterase	ChEMBL.	No reference
Inhibition (binding)	< 50 %	Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain homogenate at 10 uM	ChEMBL.	22607684
Inhibition (binding)	< 50 %	Inhibition of DAT at 10 uM	ChEMBL.	22607684
Inhibition (binding)	< 50 %	Inhibition of NET at 10 uM	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT5A receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of M5 muscarinic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of beta3 adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of alpha1B adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of H4 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of beta1 adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT7 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT1A receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT1B receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of beta2 adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of D1 dopamine receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of H2 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT1E receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT2C receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of alpha1A adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of kappa opioid receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of D3 dopamine receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of alpha2B adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of alpha1D adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of D2 dopamine receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of M3 muscarinic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of H1 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of mu opioid receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of H3 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT2A receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of M2 muscarinic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT6 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of D5 dopamine receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT1D receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of delta opioid receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of M4 muscarinic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of M1 muscarinic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of alpha2C adrenergic receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT2B receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of 5-HT3 receptor	ChEMBL.	22607684
Ki (binding)		Inhibition of alpha2A adrenergic receptor	ChEMBL.	22607684
Ki (binding)	= 30 nM	Binding affinity towards nicotinic acetylcholine receptor alpha4-beta2 from rat brain homogenates	ChEMBL.	14698195
Ki (binding)	= 30 nM	Binding affinity towards nicotinic acetylcholine receptor alpha4-beta2 from rat brain homogenates	ChEMBL.	14698195
Ki (binding)	> 10000 nM	Inhibition of SERT	ChEMBL.	22607684
Ki (binding)	= 16.4 uM	Displacement of [3H]alpha-bungarotoxin from nAChR in Musca domestica (house fly) head membrane after 60 min by scintillation counting	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by CAS
ChEMBL: CHEMBL148489
PubChem: 67786

Bibliographic References

2 literature references were collected for this gene.

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Detailed information for compound 257142