Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromobox protein, putative | 0.0063 | 0.0724 | 0.1711 |
Echinococcus granulosus | Chromo domain | 0.001 | 0.0001 | 0.0001 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0251 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0306 | 0.0338 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0669 | 0.9044 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0033 | 0.0306 | 0.0305 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0024 | 0.0188 | 0.0138 |
Echinococcus granulosus | dihydrofolate reductase | 0.0182 | 0.236 | 0.2609 |
Loa Loa (eye worm) | acyl carrier protein | 0.001 | 0.0002 | 0.0001 |
Mycobacterium ulcerans | polyketide synthase | 0.0023 | 0.0168 | 0.0117 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0015 | 0.0071 | 0.0072 |
Brugia malayi | beta-lactamase | 0.0033 | 0.0306 | 0.0338 |
Echinococcus multilocularis | Chromo domain | 0.001 | 0.0001 | 0.0001 |
Schistosoma mansoni | jumonji domain containing protein | 0.0069 | 0.0801 | 0.0885 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0148 | 0.0163 |
Onchocerca volvulus | 0.0039 | 0.0397 | 0.0438 | |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0015 | 0.0071 | 0.0078 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0.0306 | 0.027 |
Onchocerca volvulus | 0.001 | 0.0001 | 0.000000017162 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0306 | 0.0338 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0321 | 0.0354 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0251 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0033 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0042 | 0.0442 | 0.0487 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0624 | 0.8425 | 0.8489 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0033 | 0.0306 | 0.0338 |
Brugia malayi | CHD4 protein | 0.0012 | 0.0025 | 0.0026 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0624 | 0.8425 | 0.9315 |
Brugia malayi | SET domain containing protein | 0.0011 | 0.0015 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0055 | 0.006 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.001 | 0.0001 | 0.0001 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0037 | 0.0363 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0379 | 0.0417 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0034 | 0.0321 | 0.0318 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0335 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0336 | 0.037 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.0306 | 0.0258 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0023 | 0.0168 | 0.0117 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0086 | 0.1045 | 0.1053 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0033 | 0.0306 | 0.0338 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0739 | 1 | 1 |
Onchocerca volvulus | Alhambra homolog | 0.0026 | 0.0221 | 0.0244 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0026 | 0.0221 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.024 | 0.0264 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0321 | 0.0354 |
Echinococcus granulosus | chromobox protein 2 | 0.001 | 0.0001 | 0.0001 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0042 | 0.0442 | 0.0488 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.006 | 0.0679 | 0.0633 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0012 | 0.0025 | 0.0026 |
Brugia malayi | MH2 domain containing protein | 0.0108 | 0.1341 | 0.1482 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0344 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0478 | 0.0528 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0043 | 0.0445 | 0.0491 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0027 | 0.023 | 0.0229 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0033 | 0.0306 | 0.0301 |
Brugia malayi | beta-lactamase family protein | 0.0033 | 0.0306 | 0.0338 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0055 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0306 | 0.0338 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0182 | 0.236 | 0.258 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0033 | 0.0305 | 0.0338 |
Loa Loa (eye worm) | beta-lactamase | 0.0033 | 0.0306 | 0.0338 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0026 | 0.0216 | 0.0239 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0033 | 0.0306 | 0.0722 |
Brugia malayi | Dihydrofolate reductase | 0.0182 | 0.236 | 0.2608 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0024 | 0.0188 | 0.0138 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0203 | 0.0477 |
Brugia malayi | thymidylate synthase | 0.0669 | 0.9044 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0014 | 0.0055 | 0.0061 |
Mycobacterium ulcerans | thymidylate synthase | 0.0669 | 0.9044 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0026 | 0.0221 | 0.022 |
Mycobacterium tuberculosis | Conserved protein | 0.0033 | 0.0306 | 0.0301 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0318 | 0.4229 | 0.4655 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0034 | 0.0321 | 0.0355 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0018 | 0.0108 | 0.0049 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0054 | 0.0607 | 0.067 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0026 | 0.0221 | 0.0223 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0014 | 0.0055 | 0.0056 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0033 | 0.0306 | 0.0338 |
Echinococcus granulosus | thymidylate synthase | 0.0669 | 0.9044 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0045 | 0.0478 | 0.0528 |
Schistosoma mansoni | zinc finger protein | 0.0014 | 0.0049 | 0.0053 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0035 | 0.0334 | 0.0336 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0042 | 0.0442 | 0.0445 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0014 | 0.0055 | 0.006 |
Trichomonas vaginalis | chromobox protein, putative | 0.0038 | 0.0381 | 0.0899 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0012 | 0.0025 | 0.0026 |
Brugia malayi | hypothetical protein | 0.0137 | 0.1735 | 0.1918 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0318 | 0.4229 | 0.42 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0015 | 0.006 | 0.0059 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0102 | 0.0112 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.0306 | 0.0258 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0034 | 0.0321 | 0.0287 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0055 | 0.006 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0042 | 0.0442 | 0.0487 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0024 | 0.0188 | 0.0169 |
Onchocerca volvulus | 0.0214 | 0.28 | 0.3095 | |
Brugia malayi | beta-lactamase family protein | 0.0033 | 0.0306 | 0.0338 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0033 | 0.0306 | 0.0301 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0182 | 0.236 | 0.2608 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.006 | 0.0679 | 0.075 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0148 | 0.0163 |
Mycobacterium ulcerans | thioesterase | 0.0019 | 0.0117 | 0.0059 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0108 | 0.1341 | 0.1482 |
Onchocerca volvulus | 0.0033 | 0.0306 | 0.0338 | |
Echinococcus granulosus | chromobox protein 1 | 0.0063 | 0.0724 | 0.0801 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0739 | 1 | 1 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0041 | 0.0416 | 0.0459 |
Echinococcus granulosus | zinc finger protein | 0.0018 | 0.0102 | 0.0113 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0739 | 1 | 1 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0182 | 0.236 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0389 | 0.0429 |
Echinococcus multilocularis | thymidylate synthase | 0.0669 | 0.9044 | 0.9113 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0669 | 0.9044 | 1 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0669 | 0.9044 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0624 | 0.8425 | 0.9315 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0033 | 0.0306 | 0.027 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.006 | 0.0679 | 0.0633 |
Onchocerca volvulus | 0.0137 | 0.1735 | 0.1918 | |
Echinococcus multilocularis | zinc finger protein | 0.0018 | 0.0102 | 0.0103 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.006 | 0.0679 | 0.075 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0024 | 0.0188 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0442 | 0.0487 |
Schistosoma mansoni | bromodomain containing protein | 0.0057 | 0.0645 | 0.0712 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0018 | 0.0108 | 0.0049 |
Brugia malayi | Bromodomain containing protein | 0.0068 | 0.079 | 0.0873 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0033 | 0.0306 | 0.0722 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0182 | 0.236 | 0.2557 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0023 | 0.0168 | 0.0117 |
Loa Loa (eye worm) | thymidylate synthase | 0.0669 | 0.9044 | 1 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0015 | 0.0071 | 0.0079 |
Brugia malayi | PHD-finger family protein | 0.0023 | 0.0169 | 0.0185 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0023 | 0.0168 | 0.0185 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0033 | 0.0306 | 0.0301 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0108 | 0.1341 | 0.1482 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0033 | 0.0306 | 0.0301 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0045 | 0.0478 | 0.0528 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0022 | 0.0159 | 0.0137 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0032 | 0.0297 | 0.03 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0033 | 0.0306 | 0.0301 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0251 | 0.0253 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0026 | 0.0221 | 0.0245 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0023 | 0.0168 | 0.0117 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0026 | 0.0221 | 0.0244 |
Trichomonas vaginalis | chromobox protein, putative | 0.0063 | 0.0724 | 0.1711 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0344 | 0.0812 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0055 | 0.006 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0024 | 0.0188 | 0.0138 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0023 | 0.0168 | 0.0148 |
Brugia malayi | dihydrofolate reductase family protein | 0.0182 | 0.236 | 0.2608 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0321 | 0.0354 |
Trichomonas vaginalis | chromobox protein, putative | 0.0038 | 0.0381 | 0.0899 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0182 | 0.236 | 0.2378 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0033 | 0.0306 | 0.0338 |
Onchocerca volvulus | 0.0033 | 0.0306 | 0.0338 | |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0016 | 0.0079 | 0.0078 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0086 | 0.1045 | 0.1155 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0739 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0045 | 0.0478 | 0.0528 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0033 | 0.0306 | 0.027 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.0221 | 0.0244 |
Brugia malayi | Pre-SET motif family protein | 0.0027 | 0.023 | 0.0253 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.006 | 0.0679 | 0.0633 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.006 | 0.0679 | 0.0633 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0037 | 0.0372 | 0.041 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0021 | 0.0148 | 0.0125 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0016 | 0.0081 | 0.0051 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0034 | 0.0321 | 0.0318 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.023 | 0.0253 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0344 | 0.038 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0033 | 0.0306 | 0.0339 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0022 | 0.0159 | 0.0137 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.006 | 0.0679 | 0.0751 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0035 | 0.0334 | 0.0369 |
Brugia malayi | chromobox protein homolog 3 | 0.0035 | 0.0344 | 0.038 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0019 | 0.0117 | 0.0059 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0027 | 0.023 | 0.0232 |
Echinococcus multilocularis | Chromobox protein 3 | 0.001 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0023 | 0.0168 | 0.0148 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0026 | 0.0221 | 0.022 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0035 | 0.0344 | 0.038 |
Brugia malayi | jmjC domain containing protein | 0.0086 | 0.1045 | 0.1154 |
Brugia malayi | Pre-SET motif family protein | 0.0188 | 0.2443 | 0.27 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0033 | 0.0306 | 0.0722 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0055 | 0.006 |
Onchocerca volvulus | 0.0021 | 0.0148 | 0.0163 | |
Schistosoma mansoni | chromobox protein | 0.0063 | 0.0724 | 0.08 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0033 | 0.0306 | 0.0722 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0033 | 0.0305 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0306 | 0.0338 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0203 | 0.0477 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0381 | 0.042 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0016 | 0.0079 | 0.0086 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0023 | 0.0168 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0221 | 0.0244 |
Onchocerca volvulus | 0.0669 | 0.9044 | 1 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0208 | 0.2715 | 0.2974 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0365 | 0.0403 |
Mycobacterium ulcerans | polyketide synthase | 0.0024 | 0.0188 | 0.0138 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0019 | 0.0116 | 0.0127 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0063 | 0.0724 | 0.08 |
Echinococcus granulosus | chromobox protein 1 | 0.0063 | 0.0724 | 0.0801 |
Trichomonas vaginalis | set domain proteins, putative | 0.0214 | 0.28 | 0.6619 |
Mycobacterium tuberculosis | Conserved protein | 0.0033 | 0.0306 | 0.0301 |
Loa Loa (eye worm) | fatty acid synthase | 0.0022 | 0.0164 | 0.0181 |
Schistosoma mansoni | dihydrofolate reductase | 0.0182 | 0.236 | 0.2608 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0018 | 0.0108 | 0.0049 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.0306 | 0.0305 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.002 | 0.0139 | 0.0153 |
Echinococcus multilocularis | GPCR, family 2 | 0.0014 | 0.0055 | 0.0056 |
Brugia malayi | Heterochromatin protein 1 | 0.0063 | 0.0724 | 0.08 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0031 | 0.0282 | 0.0311 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.002 | 0.0139 | 0.0154 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0739 | 1 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0734 | 0.9924 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0024 | 0.0188 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0306 | 0.0338 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0034 | 0.0321 | 0.0287 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0011 | 0.0016 | 0.0015 |
Echinococcus granulosus | jumonji domain containing protein | 0.0037 | 0.0363 | 0.0401 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0014 | 0.0055 | 0.006 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.006 | 0.0679 | 0.075 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0023 | 0.0168 | 0.0117 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0014 | 0.0055 | 0.0061 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0012 | 0.0025 | 0.0025 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0054 | 0.06 | 0.0605 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0018 | 0.0112 | 0.0085 |
Mycobacterium leprae | conserved hypothetical protein | 0.0033 | 0.0306 | 0.027 |
Plasmodium vivax | SET domain protein, putative | 0.0027 | 0.023 | 0.0229 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0024 | 0.0188 | 0.0169 |
Trichomonas vaginalis | esterase, putative | 0.0033 | 0.0306 | 0.0722 |
Echinococcus granulosus | Chromobox protein 3 | 0.001 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | beta-lactamase | 0.0033 | 0.0306 | 0.027 |
Echinococcus granulosus | GPCR family 2 | 0.0014 | 0.0055 | 0.0061 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.006 | 0.0679 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0321 | 0.0354 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0014 | 0.0055 | 0.006 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0033 | 0.0306 | 0.0722 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0306 | 0.0258 |
Brugia malayi | hypothetical protein | 0.0318 | 0.4229 | 0.4675 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0012 | 0.0025 | 0.0027 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0023 | 0.0168 | 0.0117 |
Giardia lamblia | PHD finger protein 15 | 0.0026 | 0.0221 | 0.5 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0024 | 0.0188 | 0.0138 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0023 | 0.0168 | 0.0117 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0024 | 0.0188 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0282 | 0.0311 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0033 | 0.0306 | 0.0301 |
Echinococcus multilocularis | chromobox protein 1 | 0.0063 | 0.0724 | 0.073 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0014 | 0.0055 | 0.0056 |
Echinococcus multilocularis | chromobox protein 1 | 0.0063 | 0.0724 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.1735 | 0.1918 |
Echinococcus multilocularis | chromobox protein 2 | 0.001 | 0.0001 | 0.0001 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.001 | 0.0001 | 0.0001 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0015 | 0.0016 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0182 | 0.236 | 0.5 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.006 | 0.0679 | 0.0684 |
Mycobacterium ulcerans | lipase LipD | 0.0033 | 0.0306 | 0.027 |
Onchocerca volvulus | 0.0033 | 0.0306 | 0.0338 | |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0033 | 0.0306 | 0.0309 |
Mycobacterium tuberculosis | Conserved protein | 0.0033 | 0.0306 | 0.0301 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0015 | 0.0071 | 0.0078 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.002 | 0.0139 | 0.014 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0188 | 0.2443 | 0.27 |
Onchocerca volvulus | 0.0028 | 0.024 | 0.0264 | |
Mycobacterium ulcerans | thioesterase TesA | 0.0019 | 0.0117 | 0.0059 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0033 | 0.0306 | 0.0301 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0221 | 0.0244 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0054 | 0.06 | 0.0664 |
Schistosoma mansoni | chromobox protein | 0.0063 | 0.0724 | 0.08 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0318 | 0.4229 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.048 | 0.053 |
Plasmodium falciparum | phd finger protein, putative | 0.0026 | 0.0221 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0737 | 0.0814 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0282 | 0.0311 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0026 | 0.0221 | 0.0244 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0019 | 0.0117 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0049 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0116 | 0.0127 |
Mycobacterium leprae | Probable lipase LipE | 0.0033 | 0.0306 | 0.027 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0033 | 0.0306 | 0.0258 |
Onchocerca volvulus | 0.0037 | 0.0372 | 0.041 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0306 | 0.0338 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.