Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | jun protein | 0.0084 | 0.1347 | 0.4125 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.1864 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0135 | 0.3035 | 0.9296 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.1914 | 0.1914 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0315 | 0.1039 |
Brugia malayi | bZIP transcription factor family protein | 0.0084 | 0.1347 | 0.4437 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1271 | 0.4189 |
Echinococcus multilocularis | acetylcholinesterase | 0.0135 | 0.3035 | 0.9296 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0084 | 0.1347 | 0.4125 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3035 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.1666 | 0.5102 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0198 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3035 | 1 |
Schistosoma mansoni | jun-related protein | 0.0068 | 0.0832 | 0.0832 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.3265 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0084 | 0.1347 | 0.4125 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0832 | 0.0832 |
Echinococcus granulosus | jun protein | 0.0084 | 0.1347 | 0.4125 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0135 | 0.3035 | 0.3035 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1864 | 0.6141 |
Brugia malayi | Carboxylesterase family protein | 0.0135 | 0.3035 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.3265 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.1864 | 0.5709 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0135 | 0.3035 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0135 | 0.3035 | 0.9296 |
Onchocerca volvulus | 0.0066 | 0.0757 | 0.5 | |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.1666 | 0.5102 |
Loa Loa (eye worm) | carboxylesterase | 0.0135 | 0.3035 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0135 | 0.3035 | 0.9296 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0135 | 0.3035 | 0.9296 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0757 | 0.2493 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0135 | 0.3035 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.1864 | 0.5709 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.1864 | 0.6141 |
Echinococcus multilocularis | acetylcholinesterase | 0.0135 | 0.3035 | 0.9296 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.