Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0121 | 0.118 | 0.1869 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0256 | 0.6314 | 0.6151 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0256 | 0.6314 | 0.6151 |
Loa Loa (eye worm) | hypothetical protein | 0.0353 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0098 | 0.0305 | 0.0483 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0121 | 0.118 | 0.079 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0256 | 0.6314 | 0.6151 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0112 | 0.0838 | 0.1326 |
Echinococcus granulosus | tyrosine kinase | 0.0101 | 0.0424 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0256 | 0.6314 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0101 | 0.0424 | 0.0672 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0101 | 0.0424 | 0.0672 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0135 | 0.173 | 0.173 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0256 | 0.6314 | 0.6151 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0135 | 0.173 | 0.0974 |
Schistosoma mansoni | nuclear hormone receptor | 0.0121 | 0.118 | 0.0374 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0256 | 0.6314 | 0.6151 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0121 | 0.118 | 0.1869 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0121 | 0.118 | 0.0374 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0112 | 0.0838 | 0.1326 |
Brugia malayi | tailless protein | 0.0121 | 0.118 | 0.079 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0121 | 0.118 | 0.1869 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0353 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0256 | 0.6314 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0256 | 0.6314 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0256 | 0.6314 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0256 | 0.6314 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0112 | 0.0838 | 0.1326 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0121 | 0.118 | 0.1869 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.173 | 0.173 |
Loa Loa (eye worm) | SRC-1 | 0.0112 | 0.0838 | 0.0838 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0112 | 0.0838 | 0.1326 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0256 | 0.6314 | 1 |
Brugia malayi | ecdysone receptor | 0.0121 | 0.118 | 0.079 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0135 | 0.173 | 0.1364 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0101 | 0.0424 | 0.0672 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0112 | 0.0838 | 0.1326 |
Echinococcus granulosus | FTZ F1 alpha | 0.0256 | 0.6314 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0256 | 0.6314 | 0.6151 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0135 | 0.173 | 0.274 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0256 | 0.6314 | 0.5978 |
Onchocerca volvulus | 0.03 | 0.7982 | 0.7712 | |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Schistosoma mansoni | thyroid hormone receptor | 0.0256 | 0.6314 | 0.5978 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0112 | 0.0838 | 0.1326 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0256 | 0.6314 | 0.5978 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0256 | 0.6314 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0121 | 0.118 | 0.1869 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0112 | 0.0838 | 0.1326 |
Schistosoma mansoni | nuclear hormone receptor | 0.0256 | 0.6314 | 0.5978 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0353 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0121 | 0.118 | 0.0374 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0256 | 0.6314 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0256 | 0.6314 | 0.5978 |
Brugia malayi | hypothetical protein | 0.0121 | 0.118 | 0.079 |
Brugia malayi | hypothetical protein | 0.0121 | 0.118 | 0.079 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0121 | 0.118 | 0.1869 |
Brugia malayi | nuclear receptor NHR-67 | 0.0121 | 0.118 | 0.079 |
Brugia malayi | nuclear hormone receptor | 0.0121 | 0.118 | 0.079 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0112 | 0.0838 | 0.1326 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0256 | 0.6314 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0256 | 0.6314 | 0.5821 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0121 | 0.118 | 0.1869 |
Brugia malayi | conserved hypotetical protein | 0.0121 | 0.118 | 0.079 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0256 | 0.6314 | 0.5978 |
Brugia malayi | nuclear receptor RXR | 0.0121 | 0.118 | 0.079 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Schistosoma mansoni | nuclear receptor | 0.0121 | 0.118 | 0.0374 |
Brugia malayi | nuclear receptor NHR-88 | 0.0256 | 0.6314 | 0.6151 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0256 | 0.6314 | 0.6151 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0256 | 0.6314 | 0.6151 |
Loa Loa (eye worm) | DR-78 | 0.0121 | 0.118 | 0.118 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0101 | 0.0424 | 0.0672 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0121 | 0.118 | 0.079 |
Brugia malayi | SRC-1 | 0.0112 | 0.0838 | 0.0432 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0256 | 0.6314 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0256 | 0.6314 | 0.6151 |
Brugia malayi | hypothetical protein | 0.0135 | 0.173 | 0.1364 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0256 | 0.6314 | 0.6314 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0256 | 0.6314 | 0.5978 |
Onchocerca volvulus | 0.0256 | 0.6314 | 0.5821 | |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0256 | 0.6314 | 0.6151 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0256 | 0.6314 | 0.5978 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0256 | 0.6314 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0121 | 0.118 | 0.1869 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0256 | 0.6314 | 0.5978 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0121 | 0.118 | 0.0374 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0135 | 0.173 | 0.1364 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0112 | 0.0838 | 0.1326 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Schistosoma mansoni | nuclear receptor | 0.0121 | 0.118 | 0.0374 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0112 | 0.0838 | 0.1326 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0256 | 0.6314 | 0.5821 |
Schistosoma mansoni | nuclear hormone receptor | 0.0121 | 0.118 | 0.0374 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0256 | 0.6314 | 0.6314 |
Loa Loa (eye worm) | TK protein kinase | 0.0101 | 0.0424 | 0.0424 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0256 | 0.6314 | 0.5978 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0256 | 0.6314 | 0.5978 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0101 | 0.0424 | 0.0672 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0256 | 0.6314 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.173 | 0.173 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0135 | 0.173 | 0.274 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0121 | 0.118 | 0.079 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0256 | 0.6314 | 0.6314 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0256 | 0.6314 | 0.6151 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0112 | 0.0838 | 0.1326 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Schistosoma mansoni | coup transcription factor | 0.0256 | 0.6314 | 0.5978 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Loa Loa (eye worm) | hypothetical protein | 0.0353 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0256 | 0.6314 | 0.6151 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0112 | 0.0838 | 0.1326 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.6314 | 0.6314 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.173 | 0.173 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0112 | 0.0838 | 0.1326 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0256 | 0.6314 | 0.6151 |
Schistosoma mansoni | thyroid hormone receptor | 0.0256 | 0.6314 | 0.5978 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0256 | 0.6314 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0121 | 0.118 | 0.079 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.173 | 0.173 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0112 | 0.0838 | 0.1326 |
Brugia malayi | nuclear hormone receptor | 0.0256 | 0.6314 | 0.6151 |
Entamoeba histolytica | protein kinase, putative | 0.009 | 0 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0256 | 0.6314 | 0.6151 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.173 | 0.173 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0121 | 0.118 | 0.1869 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0121 | 0.118 | 0.0374 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0256 | 0.6314 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0256 | 0.6314 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0112 | 0.0838 | 0.1326 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0121 | 0.118 | 0.118 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0135 | 0.173 | 0.0974 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0098 | 0.0305 | 0.0483 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0256 | 0.6314 | 0.6151 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0121 | 0.118 | 0.079 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0121 | 0.118 | 0.1869 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0256 | 0.6314 | 0.5821 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0121 | 0.118 | 0.1869 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0121 | 0.118 | 0.118 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0121 | 0.118 | 0.079 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0121 | 0.118 | 0.079 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0112 | 0.0838 | 0.1326 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0112 | 0.0838 | 0.1326 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0121 | 0.118 | 0.1869 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0256 | 0.6314 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0256 | 0.6314 | 0.6314 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0256 | 0.6314 | 0.6314 |
Brugia malayi | nuclear receptor RXR | 0.0135 | 0.173 | 0.1364 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0256 | 0.6314 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0256 | 0.6314 | 0.6314 |
Onchocerca volvulus | 0.0353 | 1 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0256 | 0.6314 | 0.6314 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0256 | 0.6314 | 0.6151 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0121 | 0.118 | 0.118 |
Brugia malayi | hypothetical protein | 0.0135 | 0.173 | 0.1364 |
Brugia malayi | ecdysteroid receptor | 0.0256 | 0.6314 | 0.6151 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0256 | 0.6314 | 0.6314 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0256 | 0.6314 | 0.6151 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.118 | 0.118 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.