Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0919 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0841 | 0.8784 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0273 | 0.0127 |
Echinococcus granulosus | glycine receptor subunit beta | 0.004 | 0.2221 | 0.3502 |
Onchocerca volvulus | 0.0022 | 0.049 | 0.1437 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.02 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0841 | 0.8784 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0841 | 0.0996 |
Brugia malayi | Cation transporter family protein | 0.004 | 0.2221 | 0.2221 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.004 | 0.2221 | 0.2221 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0273 | 0.0127 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1854 | 1 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.004 | 0.2221 | 0.2221 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.3387 | 0.5522 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.004 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0841 | 0.0654 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1854 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0028 | 0.1054 | 0.137 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.004 | 0.2221 | 0.3502 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.004 | 0.2221 | 0.2221 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.02 | 0.02 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.5972 | 1 |
Onchocerca volvulus | 0.0022 | 0.049 | 0.1437 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.004 | 0.2221 | 0.3502 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0841 | 0.0996 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.1028 | 0.1028 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.3387 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.004 | 0.2221 | 0.2063 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.1854 | 0.2867 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 1 | 1 |
Onchocerca volvulus | 0.004 | 0.2221 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0022 | 0.049 | 0.049 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.1054 | 0.137 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0026 | 0.0919 | 1 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.004 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | Cation transporter family protein | 0.004 | 0.2221 | 0.2221 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.004 | 0.2221 | 0.3502 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.004 | 0.2221 | 0.2221 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0019 | 0.02 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.004 | 0.2221 | 0.2221 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.004 | 0.2221 | 0.3502 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0273 | 0.0153 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.004 | 0.2221 | 0.3502 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.004 | 0.2221 | 0.2063 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 1 | 1 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0022 | 0.049 | 0.0297 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.004 | 0.2221 | 0.2221 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.049 | 0.1373 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0022 | 0.049 | 0.0503 |
Schistosoma mansoni | flap endonuclease-1 | 0.0024 | 0.0684 | 0.0839 |
Onchocerca volvulus | 0.004 | 0.2221 | 1 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.1854 | 0.2867 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4666 | 0.7736 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.004 | 0.2221 | 0.2063 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.004 | 0.2221 | 0.3502 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | Cation transporter family protein | 0.004 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.4666 | 0.4557 |
Brugia malayi | hypothetical protein | 0.0019 | 0.02 | 0.02 |
Onchocerca volvulus | 0.004 | 0.2221 | 1 | |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.3387 | 1 |
Loa Loa (eye worm) | LGC-31 protein | 0.004 | 0.2221 | 0.2063 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.004 | 0.2221 | 0.2063 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1854 | 0.2867 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.004 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.004 | 0.2221 | 0.2221 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0026 | 0.0854 | 0.1134 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1854 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0273 | 0.0075 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.1054 | 0.1502 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0022 | 0.049 | 0.049 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.3387 | 0.4744 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.4666 | 0.7736 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.1054 | 0.137 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0841 | 0.8784 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.4666 | 0.4666 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.1028 | 0.0845 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | Flap endonuclease-1 | 0.0026 | 0.0919 | 0.0919 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0019 | 0.02 | 0.02 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4666 | 0.7736 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.004 | 0.2221 | 0.2221 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | nAChR subunit | 0.0022 | 0.049 | 0.0503 |
Brugia malayi | hypothetical protein | 0.0036 | 0.1854 | 0.1854 |
Onchocerca volvulus | Putative nachr subunit | 0.004 | 0.2221 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.004 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0273 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.5972 | 0.5972 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Echinococcus multilocularis | nAChR subunit | 0.0022 | 0.049 | 0.0503 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0026 | 0.0919 | 0.1134 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0026 | 0.0854 | 0.1134 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0022 | 0.049 | 0.049 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.5972 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.02 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Onchocerca volvulus | 0.004 | 0.2221 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.004 | 0.2221 | 0.2221 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.004 | 0.2221 | 0.2221 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.004 | 0.2221 | 0.3502 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0919 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.1854 | 0.2867 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.4666 | 0.4557 |
Brugia malayi | hypothetical protein | 0.0019 | 0.02 | 0.02 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4666 | 0.7736 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.004 | 0.2221 | 0.3502 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.0919 | 0.1247 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1854 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4666 | 0.7736 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0019 | 0.02 | 0.02 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.4666 | 0.7736 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0273 | 0.0127 |
Echinococcus multilocularis | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0841 | 0.0996 |
Brugia malayi | hypothetical protein | 0.0019 | 0.02 | 0.02 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0026 | 0.0854 | 0.1134 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.004 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | ACC-1 protein | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0019 | 0.02 | 0.02 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0022 | 0.049 | 0.049 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.004 | 0.2221 | 0.3502 |
Onchocerca volvulus | 0.004 | 0.2221 | 1 | |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.004 | 0.2221 | 0.3502 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.004 | 0.2221 | 0.3502 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0026 | 0.0919 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.004 | 0.2221 | 0.3502 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.004 | 0.2221 | 0.2221 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.5972 | 0.589 |
Plasmodium falciparum | flap endonuclease 1 | 0.0026 | 0.0919 | 0.1134 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.5972 | 1 |
Schistosoma mansoni | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.004 | 0.2221 | 0.3502 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.3387 | 0.5522 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Brugia malayi | RNA binding protein | 0.0066 | 0.4666 | 0.4666 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.5972 | 1 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0919 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.5972 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.004 | 0.2221 | 0.3502 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0022 | 0.049 | 0.0503 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.004 | 0.2221 | 0.2063 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.004 | 0.2221 | 0.3502 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.004 | 0.2221 | 0.3502 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.004 | 0.2221 | 0.2221 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0022 | 0.049 | 0.0503 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4666 | 0.7736 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.4666 | 0.4557 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.4666 | 0.4666 |
Echinococcus granulosus | nAChR subunit | 0.004 | 0.2221 | 0.3502 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0841 | 0.8784 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0026 | 0.0919 | 0.1134 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | hypothetical protein | 0.0019 | 0.02 | 0.02 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.5972 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0273 | 0.0153 |
Entamoeba histolytica | Flap nuclease, putative | 0.0026 | 0.0919 | 0.4087 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0273 | 0.0127 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0841 | 0.0841 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2221 | 0.2063 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.004 | 0.2221 | 0.3502 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0026 | 0.0919 | 0.0734 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.0919 | 0.1247 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.004 | 0.2221 | 0.3502 |
Onchocerca volvulus | 0.004 | 0.2221 | 1 | |
Echinococcus granulosus | glycine receptor subunit beta | 0.004 | 0.2221 | 0.3502 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0273 | 0.0273 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0841 | 0.0996 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.049 | 0.0297 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | = 79 uM | Tested for the cytotoxicity against CEM-SS cells (determined by the inhibition of [3H]-thymidine uptake) | ChEMBL. | No reference |
CC50 (functional) | = 79 uM | Tested for the cytotoxicity against CEM-SS cells (determined by the inhibition of [3H]-thymidine uptake) | ChEMBL. | No reference |
IC50 (functional) | = 20 uM | Tested for the inhibition of HIV-1 in CEM-SS cells measured using Syncytial assay | ChEMBL. | No reference |
IC50 (functional) | = 20 uM | Tested for the inhibition of HIV-1 in CEM-SS cells measured using Syncytial assay | ChEMBL. | No reference |
Inhibition (binding) | = 13 % | Tested for the inhibition of HIV-1 reverse transcriptase at a concentration of 10 ug/mL using a ribosomal RNA template | ChEMBL. | No reference |
Inhibition (binding) | = 13 % | Tested for the inhibition of HIV-1 reverse transcriptase at a concentration of 10 ug/mL using a ribosomal RNA template | ChEMBL. | No reference |
Inhibition (binding) | = 31 % | Tested for the inhibition of HIV-1 reverse transcriptase at a concentration of 100 ug/mL using a ribosomal RNA template | ChEMBL. | No reference |
Inhibition (binding) | = 31 % | Tested for the inhibition of HIV-1 reverse transcriptase at a concentration of 100 ug/mL using a ribosomal RNA template | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.