Detailed information for compound 263194

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 406.43 | Formula: C20H26N2O7
  • H donors: 2 H acceptors: 5 LogP: 2.17 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1N(C1C(=O)O)C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C
  • InChi: 1S/C20H26N2O7/c1-5-28-18(26)15-14(17(24)25)22(15)16(23)13(11-12-9-7-6-8-10-12)21-19(27)29-20(2,3)4/h6-10,13-15H,5,11H2,1-4H3,(H,21,27)(H,24,25)/t13-,14?,15?,22?/m0/s1
  • InChiKey: ZUPZMQSXUFFEMH-CQSZKLFBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.0695
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0592 0.1627
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3061 1
Onchocerca volvulus 0.0048 0.044 0.1924
Echinococcus granulosus CREB binding protein 0.0104 0.1165 0.2865
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0126 0.0882
Mycobacterium ulcerans hypothetical protein 0.0024 0.0126 0.0882
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0729 0.2402
Echinococcus granulosus alpha 1A adrenergic receptor 0.006 0.0592 0.1453
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Brugia malayi G protein-coupled receptor 0.006 0.0592 0.1624
Echinococcus multilocularis neuropeptide FF receptor 2 0.006 0.0592 0.059
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0499 1
Echinococcus multilocularis sex peptide receptor 0.006 0.0592 0.059
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0126 0.1534
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0017 0.0035
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0126 0.0369
Echinococcus multilocularis snurportin 1 0.0295 0.3626 0.3624
Brugia malayi Melatonin receptor type 1A 0.006 0.0592 0.1624
Echinococcus granulosus neuropeptide receptor A26 0.006 0.0592 0.1453
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0108 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.2981 0.8219
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0729 1
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0067 0.0682 0.068
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus granulosus geminin 0.0169 0.1995 0.491
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0126 0.0304
Loa Loa (eye worm) TYRA-2 protein 0.006 0.0592 0.1624
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0167 0.0164
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0729 1
Brugia malayi nuclear receptor RXR 0.0014 0.0003 0.0007
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0167 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Echinococcus granulosus peptide allatostatin:somatostatin 0.006 0.0592 0.1453
Trypanosoma cruzi hypothetical protein, conserved 0.0207 0.249 0.8343
Plasmodium vivax importin-beta 2, putative 0.0028 0.0175 0.0534
Echinococcus multilocularis serotonin receptor 0.006 0.0592 0.059
Onchocerca volvulus 0.0021 0.0086 0.0029
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0246 0.2993 0.2991
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0003 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0086 0.0233
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0167 0.0458
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0592 0.1453
Onchocerca volvulus 0.006 0.0592 0.2743
Trichomonas vaginalis AGC family protein kinase 0.0245 0.2981 0.973
Trypanosoma brucei CAAX amino terminal protease, putative 0.0094 0.1027 0.3407
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0017 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0592 0.1453
Onchocerca volvulus 0.0047 0.0424 0.1842
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.006 0.0592 0.1627
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0592 0.1624
Loa Loa (eye worm) voltage-dependent calcium channel 0.0086 0.0924 0.2534
Echinococcus granulosus intermediate filament protein 0.0026 0.0157 0.0381
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0157 0.0431
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0592 0.1627
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0592 0.1624
Leishmania major pyruvate kinase 0.0032 0.0237 0.0744
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0552 0.055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0167 0.0458
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0017 0.0014
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus multilocularis geminin 0.0169 0.1995 0.1993
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0081 0.0193
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0086 0.0968
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1318 0.3611
Onchocerca volvulus 0.006 0.0592 0.2743
Schistosoma mansoni neuropeptide receptor 0.006 0.0592 0.1627
Trypanosoma cruzi aurora B kinase, putative 0.0245 0.2981 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0017 0.0047
Echinococcus multilocularis aurora kinase A 0.0245 0.2981 0.2979
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0592 0.1627
Brugia malayi Serotonin receptor 0.006 0.0592 0.1624
Echinococcus granulosus CREB binding protein 0.0017 0.0039 0.009
Echinococcus granulosus neuropeptide receptor 0.006 0.0592 0.1453
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Echinococcus multilocularis lamin 0.0026 0.0157 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Onchocerca volvulus 0.0026 0.0157 0.0411
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Brugia malayi MH2 domain containing protein 0.0116 0.1318 0.3611
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0237 0.0651
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0237 0.0841
Echinococcus granulosus somatostatin receptor 0.006 0.0592 0.1453
Brugia malayi Serotonin receptor 0.006 0.0592 0.1624
Brugia malayi hypothetical protein 0.002 0.0081 0.0221
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.0729 1
Schistosoma mansoni hypothetical protein 0.0169 0.1995 0.55
Echinococcus granulosus g protein coupled receptor 0.006 0.0592 0.1453
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0167 0.0458
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0592 0.1627
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0086 0.0968
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0196 0.2349 0.5782
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0592 0.059
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0245 0.2981 0.2979
Echinococcus granulosus pyruvate kinase 0.0032 0.0237 0.0578
Echinococcus multilocularis CREB binding protein 0.0017 0.0039 0.0037
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0104 0.1165 0.3209
Echinococcus granulosus pyruvate kinase 0.0017 0.0034 0.0076
Mycobacterium ulcerans hypothetical protein 0.0024 0.0126 0.0882
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0499 0.6768
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0067 0.0682 0.2245
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0108 0.0306
Schistosoma mansoni ran 0.002 0.0081 0.0216
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0246 0.2993 0.8254
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0237 0.0651
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0682 0.2245
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.0695
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.002 0.0081 0.0216
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0067 0.0682 0.2245
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0196 0.2349 0.6477
Loa Loa (eye worm) hypothetical protein 0.0256 0.3125 0.8564
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0499 0.1626
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0086 0.0968
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0017 0.0034
Brugia malayi hypothetical protein 0.002 0.0081 0.0221
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3061 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Trypanosoma brucei hypothetical protein, conserved 0.0207 0.249 0.8343
Schistosoma mansoni hypothetical protein 0.0295 0.3626 1
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0034 0.0056
Brugia malayi isocitrate dehydrogenase 0.0015 0.0017 0.0047
Loa Loa (eye worm) AUR protein kinase 0.0245 0.2981 0.817
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis tar DNA binding protein 0.0065 0.066 0.0658
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0175 0.0534
Brugia malayi Dopamine receptor 0.006 0.0592 0.1624
Echinococcus multilocularis lamin dm0 0.0026 0.0157 0.0155
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1318 0.3611
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.027 0.0268
Echinococcus granulosus pyruvate kinase 0.0017 0.0034 0.0076
Loa Loa (eye worm) TAR-binding protein 0.0065 0.066 0.181
Schistosoma mansoni hypothetical protein 0.0033 0.0246 0.0673
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0237 0.2565
Brugia malayi follicle stimulating hormone receptor 0.0297 0.3648 1
Schistosoma mansoni tar DNA-binding protein 0.0065 0.066 0.1815
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0167 0.0458
Echinococcus granulosus allatostatin A receptor 0.006 0.0592 0.1453
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0086 0.023
Loa Loa (eye worm) hypothetical protein 0.0075 0.0791 0.2168
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.2061 0.6643
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.006 0.0592 0.059
Trypanosoma brucei aurora B kinase 0.0245 0.2981 1
Schistosoma mansoni hypothetical protein 0.0169 0.1995 0.55
Loa Loa (eye worm) hypothetical protein 0.0094 0.1027 0.2814
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0167 0.0454
Loa Loa (eye worm) hypothetical protein 0.0053 0.0499 0.1367
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0086 0.0233
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0729 0.227
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Trypanosoma cruzi hypothetical protein, conserved 0.0207 0.249 0.8343
Echinococcus granulosus neuropeptide FF receptor 2 0.006 0.0592 0.1453
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus granulosus CREB binding protein 0.0064 0.0649 0.1593
Brugia malayi hypothetical protein 0.0036 0.0278 0.0762
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.027 0.0739
Loa Loa (eye worm) hypothetical protein 0.0246 0.2993 0.8204
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.006 0.0592 0.2743
Brugia malayi neuropeptide F receptor 0.006 0.0592 0.1624
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0167 0.0458
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0086 0.0235
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0094 0.1027 0.3407
Schistosoma mansoni polycystin 1-related 0.002 0.0081 0.0215
Echinococcus granulosus voltage dependent calcium channel 0.0246 0.2993 0.7369
Schistosoma mansoni hypothetical protein 0.0039 0.0328 0.0897
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.066 0.181
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus granulosus tachykinin peptides receptor 99D 0.006 0.0592 0.1453
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0081 0.0192
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis RUN 0.002 0.0081 0.0078
Brugia malayi AMP-binding enzyme family protein 0.007 0.0729 0.1998
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0592 0.1624
Echinococcus multilocularis neuropeptide receptor 0.006 0.0592 0.059
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0081 0.0078
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0592 0.059
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0592 0.1453
Echinococcus granulosus tumor protein p63 0.0328 0.4061 1
Entamoeba histolytica CAAX prenyl protease family 0.0094 0.1027 0.3292
Brugia malayi Dopamine receptor protein 1 0.006 0.0592 0.1624
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0167 0.0405
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0592 0.059
Toxoplasma gondii hypothetical protein 0.0019 0.0068 0.0172
Giardia lamblia Hypothetical protein 0.0094 0.1027 0.337
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0094 0.1027 0.3407
Echinococcus granulosus CREB binding protein 0.0017 0.0039 0.009
Mycobacterium tuberculosis Conserved protein 0.0024 0.0126 0.1534
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0246 0.2993 0.8204
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0328 0.1048
Brugia malayi hypothetical protein 0.0014 0.0003 0.0007
Schistosoma mansoni amine GPCR 0.006 0.0592 0.1627
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.0023 0.0111 0.0303
Brugia malayi hypothetical protein 0.0014 0.0003 0.0007
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0126 0.0369
Echinococcus multilocularis g protein coupled receptor 0.006 0.0592 0.059
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.2981 1
Schistosoma mansoni hypothetical protein 0.006 0.0592 0.1627
Schistosoma mansoni protein kinase 0.0245 0.2981 0.8219
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0167 0.0454
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0086 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3061 1
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0086 0.0233
Schistosoma mansoni neuropeptide receptor 0.006 0.0592 0.1627
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0196 0.2349 0.2347
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.044 0.1206
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0175 0.0534
Loa Loa (eye worm) hypothetical protein 0.0028 0.0175 0.048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0592 0.1453
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0592 0.1627
Schistosoma mansoni lipoxygenase 0.002 0.0081 0.0215
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.006 0.0592 0.1627
Echinococcus multilocularis tumor protein p63 0.0328 0.4061 0.406
Echinococcus granulosus thyrotropin releasing hormone receptor 0.006 0.0592 0.1453
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.0695
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0246 0.2993 0.8254
Loa Loa (eye worm) hypothetical protein 0.0086 0.0924 0.2534
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0086 0.0205
Brugia malayi Importin beta-1 subunit 0.0028 0.0175 0.048
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0017 0.0046
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0592 0.1453
Echinococcus granulosus GPCR family 2 0.0015 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.023 0.2788 0.7641
Echinococcus granulosus sex peptide receptor 0.006 0.0592 0.1453
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Plasmodium falciparum protease, putative 0.0019 0.0068 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0167 0.0458
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0081 0.0216
Schistosoma mansoni neuropeptide f receptor 76f 0.006 0.0592 0.1627
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0167 0.0458
Brugia malayi GnHR receptor homolog 0.006 0.0592 0.1624
Echinococcus granulosus RUN 0.002 0.0081 0.0192
Schistosoma mansoni pyruvate kinase 0.0032 0.0237 0.0648
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0017 0.0014
Echinococcus multilocularis neuropeptide s receptor 0.006 0.0592 0.059
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0003 0.0007
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0086 0.0272
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0175 0.0173
Onchocerca volvulus 0.0021 0.0086 0.0029
Brugia malayi larval opioid receptor 0.006 0.0592 0.1624
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0167 0.0458
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0108 0.009
Echinococcus granulosus g protein coupled receptor 0.006 0.0592 0.1453
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0462 0.6246
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Schistosoma mansoni rab6-interacting 0.002 0.0081 0.0215
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0552 0.1354
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni hypothetical protein 0.002 0.0081 0.0215
Onchocerca volvulus Neuropeptide F receptor homolog 0.006 0.0592 0.2743
Echinococcus granulosus neuropeptide s receptor 0.006 0.0592 0.1453
Brugia malayi steroid hormone receptor 0.0027 0.0167 0.0458
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.2788 0.2786
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0592 0.1627
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0052 0.0117
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0039
Brugia malayi G-protein coupled receptor 0.006 0.0592 0.1624
Brugia malayi putative neuropeptide receptor NPR1 0.006 0.0592 0.1624
Schistosoma mansoni pyruvate kinase 0.0017 0.0034 0.0085
Onchocerca volvulus 0.0027 0.0167 0.0464
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0267 0.3271 0.3269
Brugia malayi RNA, U transporter 1 0.0079 0.0833 0.2283
Giardia lamblia Pyruvate kinase 0.0032 0.0237 0.0692
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0196 0.2349 0.6439
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0237 0.0744
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0499 0.6519
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0017 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0086 0.0235
Brugia malayi serine/threonine kinase 12 0.0245 0.2981 0.817
Echinococcus granulosus tar DNA binding protein 0.0065 0.066 0.162
Toxoplasma gondii transporter, cation channel family protein 0.0086 0.0924 0.3062
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0157 0.0431
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0592 0.1453
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0167 0.0458
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0096 0.1064 0.5269
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0167 0.0454
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0592 0.1453
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0094 0.1027 0.2826
Schistosoma mansoni hypothetical protein 0.006 0.0592 0.1627
Onchocerca volvulus 0.0021 0.0086 0.0029
Onchocerca volvulus 0.006 0.0592 0.2743
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.1946 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0081 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0086 0.0235
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0167 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0167 0.0458
Schistosoma mansoni adenoreceptor 0.006 0.0592 0.1627
Plasmodium falciparum importin beta, putative 0.0028 0.0175 0.0534
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0592 0.059
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.006 0.0592 0.059
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.006 0.0592 0.1624
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.002 0.0081 0.0216
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.002 0.0081 0.0221
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0592 0.1627
Leishmania major importin beta-1 subunit, putative 0.0022 0.0108 0.0306
Echinococcus multilocularis biogenic amine (5HT) receptor 0.006 0.0592 0.059
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0126 0.0151
Brugia malayi neuropeptide F receptor 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Toxoplasma gondii aurora kinase 0.0245 0.2981 1
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0111 0.0303
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.3061 0.839
Schistosoma mansoni loxhd1 0.002 0.0081 0.0215
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.066 0.181
Loa Loa (eye worm) hypothetical protein 0.0032 0.0237 0.0651
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0086 0.0235
Loa Loa (eye worm) hypothetical protein 0.0096 0.1064 0.2915
Schistosoma mansoni growth hormone secretagogue receptor 0.006 0.0592 0.1627
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Brugia malayi AMP-binding enzyme family protein 0.007 0.0729 0.1998
Echinococcus multilocularis somatostatin receptor 0.006 0.0592 0.059
Echinococcus multilocularis musashi 0.0026 0.0157 0.0155
Echinococcus granulosus survival motor neuron protein 1 0.023 0.2788 0.6862
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3061 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0167 0.0458
Brugia malayi photoreceptor-specific nuclear receptor 0.0256 0.3125 0.8564
Echinococcus granulosus hypothetical protein 0.006 0.0592 0.1453
Schistosoma mansoni opsin-like receptor 0.006 0.0592 0.1627
Schistosoma mansoni amine GPCR 0.006 0.0592 0.1627
Leishmania major GTP-binding protein, putative 0.002 0.0081 0.0216
Loa Loa (eye worm) hypothetical protein 0.0053 0.0499 0.1367
Entamoeba histolytica hypothetical protein 0.0022 0.0108 0.0137
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0729 1
Echinococcus multilocularis pyruvate kinase 0.0032 0.0237 0.0235
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.006 0.0592 0.1624
Brugia malayi CAAX amino terminal protease family protein 0.0094 0.1027 0.2814
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0081 0.0222
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0729 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.006 0.0592 0.1627
Echinococcus multilocularis alpha 1A adrenergic receptor 0.006 0.0592 0.059
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0445 0.1218
Echinococcus multilocularis pyruvate kinase 0.0017 0.0034 0.0031
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0167 0.0458
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0086 0.0062
Echinococcus granulosus aurora kinase A 0.0245 0.2981 0.7338
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Leishmania major hypothetical protein, conserved 0.0207 0.249 0.8343
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0237 0.0525
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Echinococcus multilocularis pyruvate kinase 0.0032 0.0237 0.0235
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.006 0.0592 0.1624
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0424 0.1163
Schistosoma mansoni myosin xvIII 0.006 0.0592 0.1627
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0086 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0167 0.0458
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0086 0.0272
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0094 0.1027 0.3173
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni biogenic amine receptor 0.006 0.0592 0.1627
Echinococcus multilocularis CREB binding protein 0.0017 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni alpha-1 adrenergic receptor 0.006 0.0592 0.1627
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0237 0.0744
Schistosoma mansoni amine GPCR 0.006 0.0592 0.1627
Brugia malayi serine/threonine protein kinase 6 0.0245 0.2981 0.817
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0167 0.0458
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0245 0.2981 1
Echinococcus granulosus serotonin receptor 0.006 0.0592 0.1453
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0237 0.0841
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0157 0.0431
Loa Loa (eye worm) hypothetical protein 0.0039 0.0328 0.0898
Echinococcus granulosus pyruvate kinase 0.0017 0.0034 0.0076
Mycobacterium ulcerans hypothetical protein 0.007 0.0729 1
Schistosoma mansoni biogenic amine receptor 0.006 0.0592 0.1627
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0592 0.059
Loa Loa (eye worm) hypothetical protein 0.0026 0.0157 0.0431
Brugia malayi Doublecortin family protein 0.002 0.0081 0.0221
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0086 0.0968
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0017 0.0014
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0086 0.0235
Echinococcus granulosus lamin 0.0026 0.0157 0.0381
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0167 0.0405
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.006 0.0592 0.1627
Schistosoma mansoni tar DNA-binding protein 0.0065 0.066 0.1815
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0167 0.0164
Schistosoma mansoni pyruvate kinase 0.0032 0.0237 0.0648
Schistosoma mansoni hypothetical protein 0.0035 0.027 0.0739
Brugia malayi ecdysteroid receptor 0.0027 0.0167 0.0458
Trichomonas vaginalis AGC family protein kinase 0.0245 0.2981 0.973
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0237 0.0651
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0328 0.0325
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0246 0.2993 0.2991
Brugia malayi hypothetical protein 0.0035 0.027 0.0741
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.006 0.0592 0.1624
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0167 0.0458
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Schistosoma mansoni ran 0.002 0.0081 0.0216
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0592 0.059
Brugia malayi Dopamine receptor protein 2 0.006 0.0592 0.1624
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0237 0.0744
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0245 0.2981 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0267 0.3271 0.8052
Chlamydia trachomatis pyruvate kinase 0.0032 0.0237 0.3935
Echinococcus granulosus importin subunit beta 1 0.0028 0.0175 0.0425
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0067 0.0682 0.2245
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0592 0.059
Schistosoma mansoni hypothetical protein 0.006 0.0592 0.1627
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0086 0.0968
Brugia malayi serine/threonine-protein kinase 6 0.0245 0.2981 0.817
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0592 0.1627
Schistosoma mansoni rab6-interacting 0.002 0.0081 0.0215
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0167 0.0454
Schistosoma mansoni amine GPCR 0.006 0.0592 0.1627
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0086 0.0272
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.006 0.0592 0.1627
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0081 0.0192
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0246 0.2993 0.2991
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0081 0.0215
Loa Loa (eye worm) hypothetical protein 0.0048 0.0445 0.1218
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0086 0.0272
Entamoeba histolytica protein kinase , putative 0.0245 0.2981 1
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0086 0.0968
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0126 0.0882
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0175 0.0534
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0237 0.0525
Schistosoma mansoni coup transcription factor 0.0027 0.0167 0.0454
Echinococcus multilocularis pyruvate kinase 0.0026 0.0149 0.0147
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0086 0.0272
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0297 0.3648 1
Schistosoma mansoni importin beta-1 0.0028 0.0175 0.0476
Schistosoma mansoni neuropeptide receptor 0.006 0.0592 0.1627
Entamoeba histolytica protein kinase, putative 0.0245 0.2981 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0729 1
Echinococcus multilocularis g protein coupled receptor 0.006 0.0592 0.059
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.006 0.0592 0.1624
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0246 0.2993 0.7369
Schistosoma mansoni opsin-like receptor 0.006 0.0592 0.1627
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Entamoeba histolytica heat shock transcription factor, putative 0.0096 0.1064 0.3418
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0086 0.0968
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0237 0.0841
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Echinococcus multilocularis g-protein coupled receptor 0.006 0.0592 0.059
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0068 0.0715
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.027 0.0659
Schistosoma mansoni tar DNA-binding protein 0.0065 0.066 0.1815
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.0729 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.002 0.0081 0.0216
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0237 0.0744
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0086 0.0233
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0328 0.1048
Onchocerca volvulus 0.0021 0.0086 0.0029
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0067 0.0682 0.2245
Brugia malayi ORL1-like opioid receptor 0.006 0.0592 0.1624
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0086 0.0968
Onchocerca volvulus 0.006 0.0592 0.2743
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0081 0.0216
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0462 0.6246
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0328 0.0898
Brugia malayi TAR-binding protein 0.0065 0.066 0.181
Echinococcus multilocularis CAAX prenyl protease 2 0.0094 0.1027 0.1024
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Treponema pallidum hypothetical protein 0.0019 0.0068 0.5
Echinococcus multilocularis fmrfamide receptor 0.006 0.0592 0.059
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0445 0.1218
Schistosoma mansoni lamin 0.0026 0.0157 0.0426
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni neuropeptide receptor 0.006 0.0592 0.1627
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0729 0.227
Onchocerca volvulus 0.006 0.0592 0.2743
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.002 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0046
Echinococcus multilocularis G protein coupled receptor 139 0.006 0.0592 0.059
Echinococcus multilocularis pyruvate kinase 0.0017 0.0034 0.0031
Brugia malayi gonadotropin-releasing hormone receptor 2 0.006 0.0592 0.1624
Brugia malayi Tachykinin-like peptides receptor 99D 0.006 0.0592 0.1624
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0081 0.0192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0592 0.1453
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0246 0.2993 0.7369
Onchocerca volvulus 0.0026 0.0157 0.0411
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0167 0.0405
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0167 0.0454
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0592 0.1624
Echinococcus granulosus g-protein coupled receptor 0.006 0.0592 0.1453
Echinococcus multilocularis tachykinin peptides receptor 99D 0.006 0.0592 0.059
Loa Loa (eye worm) hypothetical protein 0.007 0.0729 0.1998
Loa Loa (eye worm) hypothetical protein 0.002 0.0081 0.0221
Echinococcus granulosus orexin receptor type 2 0.006 0.0592 0.1453
Echinococcus granulosus fmrfamide receptor 0.006 0.0592 0.1453
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0067 0.0682 0.2245
Brugia malayi RNA binding protein 0.0065 0.066 0.181
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Loa Loa (eye worm) hypothetical protein 0.0048 0.044 0.1205
Loa Loa (eye worm) hypothetical protein 0.0053 0.0499 0.1367
Brugia malayi hypothetical protein 0.023 0.2788 0.7641
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0081 0.0222
Schistosoma mansoni tar DNA-binding protein 0.0065 0.066 0.1815
Brugia malayi putative neuropeptide receptor 0.006 0.0592 0.1624
Echinococcus multilocularis CREB binding protein 0.0072 0.0742 0.074
Echinococcus multilocularis voltage dependent calcium channel 0.0246 0.2993 0.2991
Echinococcus multilocularis voltage dependent calcium channel 0.0246 0.2993 0.2991
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0086 0.0924 0.3062
Echinococcus granulosus CAAX prenyl protease 2 0.0094 0.1027 0.2523
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.006 0.0592 0.059
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.2061 0.6643
Echinococcus multilocularis neuropeptide receptor A26 0.006 0.0592 0.059
Brugia malayi G-protein coupled receptor 0.006 0.0592 0.1624
Echinococcus multilocularis neuropeptide receptor 0.006 0.0592 0.059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0246 0.2993 0.7369
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0068 0.0715
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.0075 0.0791 0.2168
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0086 0.0233
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0167 0.0454
Echinococcus granulosus voltage dependent calcium channel 0.0086 0.0924 0.2271
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.002 0.0081 0.0216
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Loa Loa (eye worm) hypothetical protein 0.0053 0.0499 0.1367
Loa Loa (eye worm) hypothetical protein 0.0053 0.0499 0.1367
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0017 0.0046
Loa Loa (eye worm) RNA binding protein 0.0065 0.066 0.181
Leishmania major pyruvate kinase 0.0032 0.0237 0.0744
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Plasmodium falciparum pyruvate kinase 0.0032 0.0237 0.0744
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0086 0.0272
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Trichomonas vaginalis AGC family protein kinase 0.0245 0.2981 0.973
Mycobacterium tuberculosis Probable integral membrane protein 0.0019 0.0068 0.0715
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0086 0.0235
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0237 0.0651
Loa Loa (eye worm) hypothetical protein 0.0049 0.0451 0.1236
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0592 0.1453
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0049 0.0446
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0094 0.1027 0.3407
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0445 0.1218
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.0729 0.227
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0246 0.0676
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0462 0.6246
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0052 0.0117
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0167 0.0458
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0017 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Schistosoma mansoni biogenic amine receptor 0.006 0.0592 0.1627
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3061 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0126 0.0882
Loa Loa (eye worm) doublecortin family protein 0.002 0.0081 0.0221
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0167 0.0464
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0237 0.0651
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0086 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0167 0.0458
Loa Loa (eye worm) CBP-B 0.0072 0.0754 0.2066
Brugia malayi AKH receptor 0.006 0.0592 0.1624
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0328 0.0898
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0167 0.0405
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0499 0.1626
Echinococcus granulosus 7tm_1 domain containing protein 0.006 0.0592 0.1453
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0086 0.0235
Schistosoma mansoni intermediate filament proteins 0.0026 0.0157 0.0426
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3061 1
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0592 0.1453
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0081 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0592 0.059
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0017 0.0014
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.006 0.0592 0.1453
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0086 0.0968
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0167 0.0164
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0729 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0246 0.0676
Toxoplasma gondii hypothetical protein 0.0019 0.0068 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Plasmodium vivax protease, putative 0.0019 0.0068 0.0172
Loa Loa (eye worm) melatonin receptor type 1A 0.006 0.0592 0.1624
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0328 0.0898
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Loa Loa (eye worm) AUR protein kinase 0.0245 0.2981 0.817
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0167 0.0454
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0462 0.6246
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.0695
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0167 0.0164
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.006 0.0592 0.1624
Schistosoma mansoni lamin 0.0026 0.0157 0.0426
Brugia malayi HSF-type DNA-binding domain containing protein 0.0096 0.1064 0.2915
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.3061 0.839
Schistosoma mansoni histamine h1 receptor 0.006 0.0592 0.1627
Onchocerca volvulus 0.007 0.0729 0.3476
Loa Loa (eye worm) oxidoreductase 0.0021 0.0086 0.0235
Schistosoma mansoni hypothetical protein 0.0047 0.0424 0.1163
Entamoeba histolytica protein kinase, putative 0.0245 0.2981 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0086 0.0233
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Echinococcus multilocularis allatostatin A receptor 0.006 0.0592 0.059
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0068 0.0715
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0167 0.0454
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Echinococcus multilocularis g protein coupled receptor 0.006 0.0592 0.059
Schistosoma mansoni voltage-gated cation channel 0.0246 0.2993 0.8254
Echinococcus granulosus pyruvate kinase 0.0032 0.0237 0.0578
Echinococcus multilocularis orexin receptor type 2 0.006 0.0592 0.059
Onchocerca volvulus 0.006 0.0592 0.2743
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0729 0.2402
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.006 0.0592 0.1453
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0017 0.0039
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0086 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1946 0.6258
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0167 0.0458
Schistosoma mansoni hypothetical protein 0.006 0.0592 0.1627
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0295 0.3626 0.9938
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.0729 1
Brugia malayi AMP-binding enzyme family protein 0.007 0.0729 0.1998
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0237 0.0744
Echinococcus multilocularis pyruvate kinase 0.0017 0.0034 0.0031
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0039 0.0328 0.1048
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.006 0.0592 0.1453
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Brugia malayi sulfakinin receptor protein 0.006 0.0592 0.1624
Toxoplasma gondii CAAX amino terminal protease family protein 0.0019 0.0068 0.0172
Echinococcus multilocularis GPCR, family 2 0.0015 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.007 0.0729 0.1998
Brugia malayi TAZ zinc finger family protein 0.0104 0.1165 0.3194
Loa Loa (eye worm) PDE1B protein 0.0196 0.2349 0.6439
Plasmodium falciparum serine/threonine protein kinase, putative 0.0245 0.2981 1
Echinococcus multilocularis fmrfamide receptor 0.006 0.0592 0.059
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.006 0.0592 0.1627
Echinococcus multilocularis dro:myosuppressin receptor 0.006 0.0592 0.059
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.006 0.0592 0.059
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0086 0.0083
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0245 0.2981 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Loa Loa (eye worm) hypothetical protein 0.0021 0.0086 0.0235
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0167 0.0464
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0003 0.0007
Brugia malayi hypothetical protein 0.0036 0.0278 0.0762
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0237 0.0744
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0245 0.2981 0.7338
Schistosoma mansoni opsin-like receptor 0.006 0.0592 0.1627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0167 0.0458
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis CREB binding protein 0.0017 0.0039 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0729 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0126 0.0369
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0592 0.059
Entamoeba histolytica heat shock transcription factor, putative 0.0096 0.1064 0.3418
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.006 0.0592 0.059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0592 0.1627
Brugia malayi hypothetical protein 0.006 0.0592 0.1624
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0167 0.0458
Echinococcus granulosus g protein coupled receptor 0.006 0.0592 0.1453
Schistosoma mansoni survival motor neuron protein 0.0047 0.0424 0.1163
Schistosoma mansoni tar DNA-binding protein 0.0065 0.066 0.1815
Onchocerca volvulus 0.006 0.0592 0.2743
Echinococcus granulosus neuropeptide receptor 0.006 0.0592 0.1453
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0126 0.0124
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0039
Echinococcus granulosus 7TM GPCR rhodopsin 0.006 0.0592 0.1453
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0167 0.0454
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0246 0.2993 0.2991
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0592 0.1453
Loa Loa (eye worm) calcium channel 0.0246 0.2993 0.8204
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0592 0.1627
Entamoeba histolytica heat shock transcription factor, putative 0.0096 0.1064 0.3418
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.006 0.0592 0.1627
Loa Loa (eye worm) hypothetical protein 0.0027 0.0167 0.0458
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0729 0.2402
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Brugia malayi RE15519p 0.006 0.0592 0.1624
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0167 0.0458
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0167 0.0464
Echinococcus granulosus dro:myosuppressin receptor 0.006 0.0592 0.1453
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0086 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0245 0.2981 0.973
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0167 0.0454
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0086 0.0968
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0167 0.0405
Onchocerca volvulus 0.006 0.0592 0.2743
Brugia malayi nuclear hormone receptor 0.0027 0.0167 0.0458
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0167 0.0458
Onchocerca volvulus 0.006 0.0592 0.2743
Brugia malayi intermediate filament protein 0.0026 0.0157 0.0431
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0086 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0081 0.0078
Brugia malayi G protein-coupled receptor F59B2.13 0.006 0.0592 0.1624
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0245 0.2981 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0108 0.009
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0081 0.0078
Echinococcus granulosus snurportin 1 0.0295 0.3626 0.8928
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0067 0.0682 0.2245
Giardia lamblia Aurora kinase 0.0245 0.2981 1
Echinococcus granulosus lamin dm0 0.0026 0.0157 0.0381
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0237 0.2357
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0167 0.0164
Schistosoma mansoni amine GPCR 0.006 0.0592 0.1627
Echinococcus granulosus G protein coupled receptor 139 0.006 0.0592 0.1453
Leishmania major protein kinase, putative 0.0245 0.2981 1
Onchocerca volvulus 0.006 0.0592 0.2743
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0086 0.0968
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0167 0.0405
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0237 0.3097
Toxoplasma gondii hypothetical protein 0.0075 0.0791 0.2612
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0017 0.0014
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0167 0.0454
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0017 0.0047
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Brugia malayi Serotonin/octopamine receptor family protein 7 0.006 0.0592 0.1624
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0592 0.059
Schistosoma mansoni peptide (allatostatin)-like receptor 0.006 0.0592 0.1627
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0086 0.0233
Loa Loa (eye worm) hypothetical protein 0.007 0.0729 0.1998
Schistosoma mansoni lipoxygenase 0.0057 0.0552 0.1516
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.0729 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0151 0.0414
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Schistosoma mansoni CREB-binding protein 2 0.0104 0.1165 0.3209
Echinococcus multilocularis serotonin receptor 0.006 0.0592 0.059
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0086 0.0272
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0111 0.0147
Loa Loa (eye worm) hypothetical protein 0.006 0.0592 0.1624
Loa Loa (eye worm) AUR protein kinase 0.0245 0.2981 0.817
Echinococcus multilocularis G-protein coupled receptor, putative 0.006 0.0592 0.059
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0167 0.0405
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0592 0.1453
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0094 0.1027 0.2826
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0086 0.0924 0.3062
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.006 0.0592 0.059
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0034 0.0056
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0034 0.0056
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.006 0.0592 0.1624
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0167 0.0454
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0067 0.0682 0.1675
Loa Loa (eye worm) hypothetical protein 0.0021 0.0086 0.0235
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0086 0.0272
Entamoeba histolytica Ran family GTPase 0.002 0.0081 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0167 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0167 0.0458
Brugia malayi nuclear receptor NHR-88 0.0027 0.0167 0.0458
Onchocerca volvulus 0.006 0.0592 0.2743

Activities

Activity type Activity value Assay description Source Reference
ki/Ki (binding) = 188 M-1 min-1 Evaluated for second-order rate constants for the inactivation of mammalian lysosomal cathepsin L. ChEMBL. 10052963
ki/Ki (binding) = 188 M-1 min-1 Evaluated for second-order rate constants for the inactivation of mammalian lysosomal cathepsin L. ChEMBL. 10052963
ki/Ki (binding) = 505 M-1 min-1 Compound was evaluated for second-order rate constants for the inactivation of papain (vacuolar plant enzyme) ChEMBL. 10052963
ki/Ki (binding) = 505 M-1 min-1 Compound was evaluated for second-order rate constants for the inactivation of papain (vacuolar plant enzyme) ChEMBL. 10052963
ki/Ki (binding) = 1230 M-1 min-1 Evaluated for second-order rate constants for the inactivation of mammalian lysosomal cathepsin B. ChEMBL. 10052963
ki/Ki (binding) = 1230 M-1 min-1 Evaluated for second-order rate constants for the inactivation of mammalian lysosomal cathepsin B. ChEMBL. 10052963

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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