Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | chromobox protein 1 | 0.0084 | 0.1531 | 0.5035 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0084 | 0.1531 | 0.4559 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0462 | 0.1499 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0747 | 0.2574 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0441 | 0.2526 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0361 | 0.7873 | 1 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0049 | 0.073 | 0.0721 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0089 | 0.1647 | 0.5717 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0441 | 0.052 |
Plasmodium falciparum | glutathione reductase | 0.0142 | 0.2874 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0049 | 0.0747 | 0.2231 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.0962 | 0.0953 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0036 | 0.0447 | 0.1336 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0462 | 0.2976 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0058 | 0.0948 | 0.1167 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0441 | 0.2837 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.1065 | 0.3184 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0441 | 0.1317 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0209 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0441 | 0.1293 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0441 | 0.1506 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0462 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0462 | 0.1581 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0441 | 0.052 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.069 | 0.4476 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0058 | 0.0948 | 0.3107 |
Toxoplasma gondii | thioredoxin reductase | 0.0142 | 0.2874 | 1 |
Schistosoma mansoni | ferritin light chain | 0.0018 | 0.0033 | 0.0024 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0058 | 0.0948 | 0.1167 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.1065 | 0.1057 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0022 | 0.012 | 0.0366 |
Onchocerca volvulus | 0.0036 | 0.0441 | 0.566 | |
Onchocerca volvulus | 0.0034 | 0.0392 | 0.5018 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0441 | 0.1293 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.1065 | 0.3165 |
Echinococcus multilocularis | ferritin | 0.0018 | 0.0033 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.012 | 0.0331 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0089 | 0.1647 | 0.2058 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 1 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0441 | 0.1428 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0142 | 0.2874 | 0.9481 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0441 | 0.2526 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.1065 | 0.3165 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0441 | 0.2526 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.015 | 0.3058 | 0.9135 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0441 | 0.052 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0209 | 0.0626 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0441 | 0.052 |
Trichomonas vaginalis | chromobox protein, putative | 0.005 | 0.0772 | 0.5011 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0049 | 0.0747 | 0.4846 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0049 | 0.0747 | 0.0738 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.1065 | 0.1057 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0441 | 0.2526 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 0.542 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.004 | 0.0528 | 0.0519 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 1 |
Onchocerca volvulus | 0.0036 | 0.0441 | 0.566 | |
Plasmodium falciparum | thioredoxin reductase | 0.0142 | 0.2874 | 1 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0049 | 0.0747 | 0.091 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0441 | 0.052 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0441 | 0.052 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Schistosoma mansoni | apoferritin-2 | 0.0018 | 0.0033 | 0.0024 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0142 | 0.2874 | 0.8584 |
Echinococcus granulosus | ferritin | 0.0018 | 0.0033 | 0.0079 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0009 | 0.0028 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0462 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0441 | 0.1293 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0034 | 0.0392 | 0.1266 |
Onchocerca volvulus | 0.0036 | 0.0441 | 0.566 | |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0462 | 0.1581 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.1065 | 0.3495 |
Brugia malayi | Heterochromatin protein 1 | 0.0084 | 0.1531 | 0.4574 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.0962 | 0.0953 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0441 | 0.1317 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0209 | 0.0699 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Loa Loa (eye worm) | glutathione reductase | 0.0142 | 0.2874 | 0.8584 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0049 | 0.0747 | 0.244 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0009 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.012 | 0.0331 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0059 | 0.0979 | 0.3384 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1647 | 0.4907 |
Echinococcus multilocularis | muscleblind protein | 0.0149 | 0.3031 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.0034 | 0.0392 | 0.8448 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0049 | 0.0747 | 0.442 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0049 | 0.0747 | 0.2016 |
Schistosoma mansoni | chromobox protein | 0.0084 | 0.1531 | 0.1523 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0058 | 0.0948 | 0.3107 |
Echinococcus granulosus | aminopeptidase N | 0.0034 | 0.0392 | 0.1266 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0049 | 0.0747 | 0.2574 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0049 | 0.0747 | 0.442 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0374 | 0.0434 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0441 | 0.1293 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.069 | 0.8932 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0441 | 0.0868 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0036 | 0.0447 | 0.1336 |
Schistosoma mansoni | apoferritin-2 | 0.0018 | 0.0033 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0441 | 0.1293 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0462 | 0.1499 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0441 | 0.2837 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.1065 | 0.1057 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0034 | 0.0392 | 0.0685 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0034 | 0.0392 | 0.2514 |
Treponema pallidum | NADH oxidase | 0.0049 | 0.0747 | 0.442 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.0962 | 0.3153 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0441 | 0.0432 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0361 | 0.7873 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0325 | 0.7044 | 0.8943 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0441 | 0.052 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0747 | 0.2574 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0462 | 0.2976 |
Loa Loa (eye worm) | aminopeptidase N | 0.0034 | 0.0392 | 0.1146 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.012 | 0.0331 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0441 | 0.052 |
Leishmania major | cathepsin L-like protease | 0.0065 | 0.1108 | 0.3835 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0441 | 0.052 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0034 | 0.0392 | 0.1335 |
Trichomonas vaginalis | chromobox protein, putative | 0.0084 | 0.1531 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0009 | 0.0028 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 0.5717 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0149 | 0.3031 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0462 | 0.2658 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0459 | 0.1347 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0441 | 0.1317 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0049 | 0.0747 | 0.2574 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0462 | 0.2976 |
Leishmania major | trypanothione reductase | 0.0142 | 0.2874 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0049 | 0.0747 | 0.4846 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.1065 | 0.3184 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0049 | 0.0747 | 0.2574 |
Onchocerca volvulus | 0.0036 | 0.0441 | 0.566 | |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0034 | 0.0392 | 0.2514 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0441 | 0.1317 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.069 | 0.2041 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0441 | 0.2526 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0089 | 0.1647 | 0.5717 |
Brugia malayi | Peptidase family M1 containing protein | 0.0034 | 0.0392 | 0.1171 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0374 | 0.0434 |
Toxoplasma gondii | hypothetical protein | 0.0031 | 0.0317 | 0.1075 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0135 | 0.27 | 0.8905 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0034 | 0.0392 | 0.1335 |
Brugia malayi | Probable ClpP-like protease | 0.0089 | 0.1647 | 0.4921 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0009 | 0.0028 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 0.542 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0441 | 0.0432 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0051 | 0.0789 | 0.2722 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0049 | 0.0747 | 0.442 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0049 | 0.0747 | 0.5 |
Trypanosoma brucei | trypanothione reductase | 0.0142 | 0.2874 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0084 | 0.1531 | 1 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0034 | 0.0392 | 0.1335 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3031 | 0.9054 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Brugia malayi | chromobox protein homolog 3 | 0.0047 | 0.069 | 0.2063 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3031 | 0.9054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0065 | 0.1108 | 0.3835 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0049 | 0.0747 | 0.2574 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0022 | 0.012 | 0.0111 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.1065 | 0.3165 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0962 | 0.2854 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0209 | 0.0699 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0377 | 0.2419 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0962 | 0.2874 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.1065 | 0.3495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.1065 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0441 | 0.1293 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0209 | 0.0699 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0031 | 0.0317 | 0.1075 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0142 | 0.2874 | 0.3623 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0441 | 0.2837 |
Schistosoma mansoni | ferritin light chain | 0.0018 | 0.0033 | 0.0024 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0049 | 0.0747 | 0.2574 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0325 | 0.7044 | 0.8943 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0462 | 0.2658 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0377 | 0.2419 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0317 | 0.1761 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0462 | 0.1581 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0962 | 0.2874 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0049 | 0.0747 | 0.2574 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 1 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0031 | 0.0317 | 0.0362 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0441 | 0.052 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0034 | 0.0392 | 0.1335 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Plasmodium vivax | glutathione reductase, putative | 0.0142 | 0.2874 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.005 | 0.0772 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0034 | 0.0392 | 0.0685 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Echinococcus granulosus | expressed protein | 0.0018 | 0.0033 | 0.0079 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0049 | 0.0747 | 0.442 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0009 | 0.0028 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0209 | 0.0699 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0142 | 0.2874 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0049 | 0.0747 | 0.2574 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0441 | 0.2837 |
Trichomonas vaginalis | ferritin, putative | 0.0018 | 0.0033 | 0.0157 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0049 | 0.0747 | 0.2574 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0049 | 0.0747 | 0.442 |
Echinococcus granulosus | chromobox protein 1 | 0.0084 | 0.1531 | 0.5035 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0065 | 0.1108 | 0.3835 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0317 | 0.1075 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.0962 | 0.0953 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0462 | 0.1581 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0462 | 0.0453 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0462 | 0.1381 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0361 | 0.7873 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0441 | 0.1506 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0089 | 0.1647 | 0.1639 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0747 | 0.2574 |
Leishmania major | cathepsin L-like protease | 0.0065 | 0.1108 | 0.3835 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0009 | 0.0028 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0462 | 0.1357 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0033 | 0.0024 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Brugia malayi | RNA binding protein | 0.0063 | 0.1065 | 0.3184 |
Echinococcus multilocularis | aminopeptidase N | 0.0034 | 0.0392 | 0.1266 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.2471 | 0.2464 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0441 | 0.1428 |
Onchocerca volvulus | 0.0034 | 0.0392 | 0.5018 | |
Brugia malayi | hypothetical protein | 0.0034 | 0.0392 | 0.1171 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.27 | 0.2693 |
Brugia malayi | Muscleblind-like protein | 0.0149 | 0.3031 | 0.9056 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0441 | 0.1506 |
Echinococcus multilocularis | chromobox protein 1 | 0.0084 | 0.1531 | 0.5035 |
Brugia malayi | Thioredoxin reductase | 0.0142 | 0.2874 | 0.8588 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0142 | 0.2874 | 0.9481 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0049 | 0.0747 | 0.2016 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0049 | 0.0747 | 0.2574 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0065 | 0.1108 | 0.3835 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0441 | 0.1293 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0059 | 0.0962 | 0.3153 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0034 | 0.0392 | 0.2223 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0049 | 0.0747 | 0.2016 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.0962 | 0.3153 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0441 | 0.052 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0049 | 0.0747 | 0.244 |
Onchocerca volvulus | 0.0037 | 0.0459 | 0.5895 | |
Echinococcus granulosus | muscleblind protein | 0.0149 | 0.3031 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0034 | 0.0392 | 0.1266 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0325 | 0.7044 | 0.8943 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0325 | 0.7044 | 0.8943 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0441 | 0.2526 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0441 | 0.1506 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.1065 | 0.1057 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0034 | 0.0392 | 0.0383 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0065 | 0.1108 | 0.3835 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.0962 | 0.3153 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0034 | 0.0392 | 0.0685 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0325 | 0.7044 | 0.8943 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0462 | 0.0453 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0049 | 0.0747 | 0.2016 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0033 | 0.0024 |
Brugia malayi | Peptidase family M1 containing protein | 0.0034 | 0.0392 | 0.1171 |
Brugia malayi | glutathione reductase | 0.0142 | 0.2874 | 0.8588 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0058 | 0.0948 | 0.1167 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0441 | 0.1428 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0089 | 0.1647 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Leishmania major | cathepsin L-like protease | 0.0065 | 0.1108 | 0.3835 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0209 | 0.0699 |
Echinococcus multilocularis | chromobox protein 1 | 0.0084 | 0.1531 | 0.5035 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0441 | 0.1506 |
Echinococcus multilocularis | expressed protein | 0.0018 | 0.0033 | 0.0079 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0033 | 0.0024 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0441 | 0.052 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.27 | 0.2693 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Brugia malayi | PAS domain containing protein | 0.0049 | 0.073 | 0.218 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.2471 | 0.8147 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.069 | 0.4476 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0034 | 0.0392 | 0.1335 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0441 | 0.1428 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0441 | 0.1293 |
Brugia malayi | hypothetical protein | 0.0163 | 0.3346 | 1 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0033 | 0.0024 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0441 | 0.2837 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0209 | 0.0699 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0009 | 0.0028 |
Mycobacterium tuberculosis | Probable reductase | 0.0325 | 0.7044 | 0.8943 |
Trichomonas vaginalis | chromobox protein, putative | 0.005 | 0.0772 | 0.5011 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0089 | 0.1647 | 0.5717 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.2471 | 0.8147 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0441 | 0.1317 |
Schistosoma mansoni | single-minded | 0.0049 | 0.073 | 0.0721 |
Schistosoma mansoni | chromobox protein | 0.0084 | 0.1531 | 0.1523 |
Brugia malayi | hypoxia-induced factor 1 | 0.015 | 0.3058 | 0.9137 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0022 | 0.012 | 0.0386 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.023 | 0.4873 | 0.6173 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.3346 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0209 | 0.0699 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0325 | 0.7044 | 0.8943 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0361 | 0.7873 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0142 | 0.2874 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0065 | 0.1108 | 0.3372 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0441 | 0.2837 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MISS T/C (functional) | < 0.73 | In vivo blood glucose was determined in obese, hyperglycemic, hyperinsulinemic, insulin-resistant KKAy mice after a dose of 500 mg/kg for 4 days | ChEMBL. | 11312923 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.