Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Nuclear receptor subfamily 1 group I member 2 | Starlite/ChEMBL | No references |
Homo sapiens | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | Starlite/ChEMBL | No references |
Homo sapiens | nuclear factor, erythroid 2-like 2 | Starlite/ChEMBL | No references |
Homo sapiens | thyroid hormone receptor, beta | Starlite/ChEMBL | No references |
Homo sapiens | isocitrate dehydrogenase 1 (NADP+), soluble | Starlite/ChEMBL | No references |
Homo sapiens | vitamin D (1,25- dihydroxyvitamin D3) receptor | Starlite/ChEMBL | No references |
Homo sapiens | androgen receptor | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.042721 | 0.0222575 | 0.0222575 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0111356 | 0.00246937 | 0.00246937 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.241537 | 0.146814 | 0.146814 |
Schistosoma mansoni | amine GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Toxoplasma gondii | DNA topoisomerase I, putative | 0.0187359 | 0.00723096 | 0.0155872 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | adam | 0.0649717 | 0.0361974 | 0.0487925 |
Brugia malayi | prolyl oligopeptidase family protein | 0.00883161 | 0.00102596 | 0.00102596 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.00963511 | 0.00152935 | 0.00258973 |
Loa Loa (eye worm) | hypothetical protein | 0.0649717 | 0.0361974 | 0.0361974 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.178105 | 0.107075 | 0.181316 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0561004 | 0.0306396 | 0.0413008 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0109454 | 0.00235026 | 0.00316806 |
Echinococcus granulosus | serotonin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.00963511 | 0.00152935 | 0.00206149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.178105 | 0.107075 | 0.107075 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0109454 | 0.00235026 | 0.00235026 |
Brugia malayi | Integrin beta pat-3 precursor | 1.60338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Trypanosoma brucei | protein tyrosine phosphatase 1 | 0.00963511 | 0.00152935 | 0.00156246 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0109454 | 0.00235026 | 0.00235026 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0109454 | 0.00235026 | 0.00316806 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0596528 | 0.0328651 | 0.0692282 |
Schistosoma mansoni | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00650535 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.00821412 | 0.000639106 | 0.000861487 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0561004 | 0.0306396 | 0.0413008 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0124708 | 0.0033059 | 0.00445622 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Brugia malayi | G-protein coupled receptor | 0.013326 | 0.00384168 | 0.00384168 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.747668 | 0.463902 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | protein-tyrosine phosphatase 1 | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Trichomonas vaginalis | hypothetical protein | 0.0649717 | 0.0361974 | 0.371944 |
Echinococcus multilocularis | DNA topoisomerase 1 | 0.0187359 | 0.00723096 | 0.00974702 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | DNA topoisomerase I | 0.0187359 | 0.00723096 | 0.00723096 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0136748 | 0.00406019 | 0.00406019 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0501907 | 0.0269372 | 0.050828 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | DNA topoisomerase I | 0.0187359 | 0.00723096 | 0.00723096 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | RE15519p | 0.013326 | 0.00384168 | 0.00384168 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0596528 | 0.0328651 | 0.0692282 |
Echinococcus granulosus | neuropeptides capa receptor | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0124708 | 0.0033059 | 0.00559808 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.00963511 | 0.00152935 | 0.00258973 |
Brugia malayi | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | fmrfamide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Leishmania major | DNA topoisomerase IB, large subunit | 0.0140281 | 0.00428156 | 0.00703342 |
Echinococcus multilocularis | peroxidasin | 0.0139753 | 0.00424846 | 0.00572674 |
Schistosoma mansoni | organic anion transporter | 0.0111356 | 0.00246937 | 0.00418153 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | follicle stimulating hormone receptor | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | g protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0445164 | 0.0233823 | 0.0315183 |
Echinococcus granulosus | carboxylesterase 5A | 0.0104634 | 0.00204828 | 0.00276099 |
Schistosoma mansoni | coup transcription factor | 0.0109454 | 0.00235026 | 0.00397984 |
Loa Loa (eye worm) | hypothetical protein | 0.192863 | 0.116321 | 0.116321 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Giardia lamblia | Neurogenic locus notch-like protein | 0.0649717 | 0.0361974 | 1 |
Brugia malayi | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Schistosoma mansoni | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.0072077 | 0.00000859023 | 0.00000859023 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0127713 | 0.00349418 | 0.00471 |
Echinococcus multilocularis | protein jagged 2 | 0.0649717 | 0.0361974 | 0.0487925 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | integrin beta 2 | 1.19134 | 0.741863 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0109454 | 0.00235026 | 0.00316806 |
Schistosoma mansoni | pcd6 interacting protein-related | 0.00963511 | 0.00152935 | 0.00258973 |
Brugia malayi | EGF-like domain containing protein | 0.0649717 | 0.0361974 | 0.0361974 |
Onchocerca volvulus | 0.338668 | 0.207667 | 1 | |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.84661 | 0.525889 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | g protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.00883161 | 0.00102596 | 0.00173732 |
Echinococcus granulosus | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | thymidylate synthase | 0.338668 | 0.207667 | 0.279925 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0109454 | 0.00235026 | 0.00235026 |
Brugia malayi | thymidylate synthase | 0.338668 | 0.207667 | 0.207667 |
Schistosoma mansoni | voltage-gated potassium channel | 0.00965675 | 0.0015429 | 0.00261269 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0109454 | 0.00235026 | 0.00397984 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0109454 | 0.00235026 | 0.00316806 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0185966 | 0.00714368 | 0.0689955 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.0649717 | 0.0361974 | 0.0361974 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0127713 | 0.00349418 | 0.00471 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | dual specificity protein phosphatase CDC14B | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.747668 | 0.463902 | 1 |
Echinococcus multilocularis | integrin alpha 3 | 0.219163 | 0.132797 | 0.179005 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Carboxylesterase family protein | 0.0104634 | 0.00204828 | 0.00204828 |
Toxoplasma gondii | hypothetical protein | 0.0649717 | 0.0361974 | 0.078028 |
Schistosoma mansoni | integrin alpha-ps | 0.0595141 | 0.0327782 | 0.0555053 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0121072 | 0.00307808 | 0.00414912 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0185966 | 0.00714368 | 0.0689955 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Dopamine receptor | 0.013326 | 0.00384168 | 0.00384168 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.84661 | 0.525889 | 1 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.00963511 | 0.00152935 | 0.00156246 |
Loa Loa (eye worm) | hypothetical protein | 0.00883161 | 0.00102596 | 0.00102596 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | adam | 0.0649717 | 0.0361974 | 0.0487925 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0561004 | 0.0306396 | 0.0306396 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0136748 | 0.00406019 | 0.00406019 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0109454 | 0.00235026 | 0.00397984 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.747668 | 0.463902 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus granulosus | acetylcholinesterase | 0.0104634 | 0.00204828 | 0.00276099 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Animal haem peroxidase family protein | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | Animal haem peroxidase family protein | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | Dihydrofolate reductase | 0.84661 | 0.525889 | 0.525889 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | dihydrofolate reductase | 0.84661 | 0.525889 | 0.890519 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0185966 | 0.00714368 | 0.00714368 |
Brugia malayi | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | hypothetical protein | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Mycobacterium ulcerans | thymidylate synthase | 0.338668 | 0.207667 | 0.386553 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0100765 | 0.00180585 | 0.00389273 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0185966 | 0.00714368 | 0.0689955 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Schistosoma mansoni | amine GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0136748 | 0.00406019 | 0.00406019 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.338668 | 0.207667 | 0.394635 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.00875881 | 0.000980354 | 0.00132148 |
Brugia malayi | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0679825 | 0.0380836 | 0.0513351 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus multilocularis | hedgehog | 0.0262865 | 0.0119614 | 0.0161234 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0596528 | 0.0328651 | 0.0687855 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0285426 | 0.0133748 | 0.0266784 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | hypothetical protein | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Animal haem peroxidase family protein | 0.0136748 | 0.00406019 | 0.00406019 |
Echinococcus multilocularis | dihydrofolate reductase | 0.84661 | 0.525889 | 0.708876 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.00821412 | 0.000639106 | 0.000861487 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.178105 | 0.107075 | 0.144332 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Onchocerca volvulus | 0.0111356 | 0.00246937 | 0.011891 | |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Giardia lamblia | Tenascin precursor | 0.0649717 | 0.0361974 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0561004 | 0.0306396 | 0.0518838 |
Schistosoma mansoni | receptor protein tyrosine phosphatase r (pcptp1) | 0.00963511 | 0.00152935 | 0.00258973 |
Onchocerca volvulus | 0.0111356 | 0.00246937 | 0.011891 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | hypothetical protein | 0.0547908 | 0.0298191 | 0.0504944 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0185966 | 0.00714368 | 0.0689955 |
Brugia malayi | putative neuropeptide receptor | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Lipocalin / cytosolic fatty-acid binding protein family protein | 0.0563378 | 0.0307883 | 0.0307883 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | fatty acid binding protein | 0.0445164 | 0.0233823 | 0.0395946 |
Brugia malayi | Phospholipase A2 family protein | 0.00930933 | 0.00132525 | 0.00132525 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0109454 | 0.00235026 | 0.00235026 |
Onchocerca volvulus | 0.0121072 | 0.00307808 | 0.0148222 | |
Brugia malayi | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Schistosoma mansoni | peroxidasin | 0.0136748 | 0.00406019 | 0.00687535 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0109454 | 0.00235026 | 0.0113175 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | FTZ F1 alpha | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | fibrillin 1 | 0.0649717 | 0.0361974 | 0.0487925 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0185966 | 0.00714368 | 0.166204 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0285426 | 0.0133748 | 0.0271412 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | integrin beta-2 | 1.60338 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | Peroxidase homolog | 0.0136748 | 0.00406019 | 0.0195515 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0295111 | 0.0139815 | 0.0188465 |
Giardia lamblia | Tenascin-X | 0.0649717 | 0.0361974 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Trichomonas vaginalis | pten, drome, putative | 0.00963511 | 0.00152935 | 0.0104538 |
Brugia malayi | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | TYRA-2 protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.278677 | 0.170082 | 0.170082 |
Schistosoma mansoni | fatty acid binding protein | 0.0445164 | 0.0233823 | 0.0395946 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0596528 | 0.0328651 | 0.0692282 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | integrin alpha-ps | 0.114305 | 0.0671043 | 0.113632 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0109454 | 0.00235026 | 0.00235026 |
Onchocerca volvulus | Peroxidase homolog | 0.0136748 | 0.00406019 | 0.0195515 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.00999875 | 0.00175717 | 0.00236859 |
Echinococcus granulosus | acetylcholinesterase | 0.0104634 | 0.00204828 | 0.00276099 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0136748 | 0.00406019 | 0.0195515 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Animal haem peroxidase family protein | 0.0139753 | 0.00424846 | 0.00424846 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0445164 | 0.0233823 | 0.0315183 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.00930933 | 0.00132525 | 0.00638164 |
Trypanosoma cruzi | DNA topoisomerase IB, large subunit, putative | 0.0140281 | 0.00428156 | 0.00750553 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.00935249 | 0.00135229 | 0.00182283 |
Loa Loa (eye worm) | hypothetical protein | 0.0595141 | 0.0327782 | 0.0327782 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0295111 | 0.0139815 | 0.0188465 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | peroxidasin | 0.0139753 | 0.00424846 | 0.00572674 |
Trypanosoma cruzi | prolyl endopeptidase | 0.00883161 | 0.00102596 | 0.00047546 |
Echinococcus granulosus | somatostatin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | acetylcholinesterase | 0.0104634 | 0.00204828 | 0.00276099 |
Giardia lamblia | Tenascin-like | 0.0649717 | 0.0361974 | 1 |
Schistosoma mansoni | peroxidasin | 0.0136748 | 0.00406019 | 0.00687535 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.747668 | 0.463902 | 1 |
Onchocerca volvulus | 0.0109454 | 0.00235026 | 0.0113175 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0109454 | 0.00235026 | 0.00316806 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | orexin receptor type 2 | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Dopamine receptor protein 2 | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0140281 | 0.00428156 | 0.00725022 |
Brugia malayi | Hint module family protein | 0.0072077 | 0.00000859023 | 0.00000859023 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0369788 | 0.01866 | 0.0898558 |
Loa Loa (eye worm) | hypothetical protein | 0.00930933 | 0.00132525 | 0.00132525 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | Hint module family protein | 0.0072077 | 0.00000859023 | 0.00000859023 |
Brugia malayi | G protein-coupled receptor | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.00883161 | 0.00102596 | 0.00173732 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.0111356 | 0.00246937 | 0.0033286 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | Protein-tyrosine phosphatase | 0.00999875 | 0.00175717 | 0.00175717 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Loa Loa (eye worm) | hypothetical protein | 0.0139753 | 0.00424846 | 0.00424846 |
Echinococcus granulosus | integrin alpha ps | 0.114305 | 0.0671043 | 0.0904537 |
Echinococcus multilocularis | sex peptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | integrin alpha ps | 0.114305 | 0.0671043 | 0.0904537 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus granulosus | integrin alpha 3 | 0.219163 | 0.132797 | 0.179005 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | Peroxidasin homolog | 0.0139753 | 0.00424846 | 0.0204581 |
Echinococcus granulosus | neuropeptide s receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | g-protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.00999875 | 0.00175717 | 0.00236859 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0127713 | 0.00349418 | 0.00591689 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0185966 | 0.00714368 | 0.0689955 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.41675 | 0.256584 | 0.256584 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Trypanosoma brucei | DNA topoisomerase IB, large subunit | 0.0140281 | 0.00428156 | 0.00750553 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | Dual specificity protein phosphatase CDC14B | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Brugia malayi | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.00821412 | 0.000639106 | 0.000639106 |
Schistosoma mansoni | opsin-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Giardia lamblia | hypothetical protein | 0.0649717 | 0.0361974 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | protein tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0473243 | 0.0251414 | 0.0338895 |
Schistosoma mansoni | biogenic amine receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | ORL1-like opioid receptor | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | lipocalin/cytosolic fatty-acid binding protein family protein | 0.0563378 | 0.0307883 | 0.0307883 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | serotonin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0127713 | 0.00349418 | 0.00471 |
Schistosoma mansoni | protein-tyrosine phosphatase n9 | 0.00963511 | 0.00152935 | 0.00258973 |
Toxoplasma gondii | prolyl endopeptidase | 0.00883161 | 0.00102596 | 0.00221159 |
Brugia malayi | neuropeptide F receptor | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus multilocularis | fmrfamide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | Dual oxidase homolog | 0.0136748 | 0.00406019 | 0.0195515 |
Echinococcus granulosus | g protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | DNA topoisomerase 1 | 0.0187359 | 0.00723096 | 0.00974702 |
Schistosoma mansoni | integrin alpha | 0.278677 | 0.170082 | 0.288011 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Brugia malayi | G-protein coupled receptor | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0121072 | 0.00307808 | 0.00414912 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | prolyl endopeptidase | 0.00883161 | 0.00102596 | 0.00138295 |
Echinococcus granulosus | fmrfamide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | Peroxidasin homolog | 0.0139753 | 0.00424846 | 0.0204581 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0333934 | 0.0164138 | 0.030809 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0109454 | 0.00235026 | 0.00235026 |
Schistosoma mansoni | opsin-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0109454 | 0.00235026 | 0.00316806 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.00963511 | 0.00152935 | 0.00108752 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0130913 | 0.0036946 | 0.00661289 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0103352 | 0.00196794 | 0.00250956 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0140281 | 0.00428156 | 0.00725022 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | larval opioid receptor | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | protein tyrosine phosphatase n9 | 0.00963511 | 0.00152935 | 0.00206149 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0121072 | 0.00307808 | 0.00490677 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0124708 | 0.0033059 | 0.00445622 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0127713 | 0.00349418 | 0.00471 |
Loa Loa (eye worm) | hypothetical protein | 0.0547908 | 0.0298191 | 0.0298191 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Schistosoma mansoni | adenoreceptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.00963511 | 0.00152935 | 0.00206149 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Giardia lamblia | High cysteine protein | 0.0649717 | 0.0361974 | 1 |
Echinococcus multilocularis | fibrillin 2 | 0.0649717 | 0.0361974 | 0.0487925 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0104634 | 0.00204828 | 0.00276099 |
Mycobacterium ulcerans | hypothetical protein | 0.0311102 | 0.0149834 | 0.0151128 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.00935249 | 0.00135229 | 0.00228991 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0127713 | 0.00349418 | 0.00471 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.0111356 | 0.00246937 | 0.0033286 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0185966 | 0.00714368 | 1 |
Brugia malayi | Serotonin receptor | 0.0586477 | 0.0322354 | 0.0322354 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0473243 | 0.0251414 | 0.0425734 |
Loa Loa (eye worm) | hypothetical protein | 0.0104634 | 0.00204828 | 0.00204828 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | integrin alpha ps | 0.0547908 | 0.0298191 | 0.0401948 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.747668 | 0.463902 | 1 |
Brugia malayi | Peroxidasin | 0.0139753 | 0.00424846 | 0.00424846 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | 0.00963511 | 0.00152935 | 0.00206149 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.00965675 | 0.0015429 | 0.00261269 |
Echinococcus granulosus | neuropeptide Y receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus multilocularis | neuropeptide s receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.164372 | 0.0984712 | 0.0984712 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.00935249 | 0.00135229 | 0.00182283 |
Brugia malayi | Protein-tyrosine phosphatase 1 | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.0185966 | 0.00714368 | 0.0343998 | |
Echinococcus granulosus | sex peptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.223886 | 0.135756 | 0.135756 |
Brugia malayi | Melatonin receptor type 1A | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | integrin alpha ps | 0.114305 | 0.0671043 | 0.0904537 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00258973 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0121072 | 0.00307808 | 0.00307808 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | fatty acid binding protein, adipocyte | 0.0295111 | 0.0139815 | 0.0188465 |
Echinococcus granulosus | dihydrofolate reductase | 0.84661 | 0.525889 | 0.708876 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.84661 | 0.525889 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | neuropeptide F receptor | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.00963511 | 0.00152935 | 0.00206149 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.178105 | 0.107075 | 0.144332 |
Loa Loa (eye worm) | sodium-independent organic anion transporter | 0.0111356 | 0.00246937 | 0.00246937 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Giardia lamblia | Neurogenic locus Notch protein precursor | 0.0649717 | 0.0361974 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.00963511 | 0.00152935 | 0.00206149 |
Brugia malayi | EGF-like domain containing protein | 0.0649717 | 0.0361974 | 0.0361974 |
Trypanosoma cruzi | MFS transporter, putative | 0.0111356 | 0.00246937 | 0.00359232 |
Echinococcus granulosus | fibrillin 2 | 0.0649717 | 0.0361974 | 0.0487925 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | neuropeptide Y receptor | 0.013326 | 0.00384168 | 0.00517842 |
Mycobacterium tuberculosis | Hypothetical protein | 0.161114 | 0.0964299 | 0.183026 |
Loa Loa (eye worm) | thymidylate synthase | 0.338668 | 0.207667 | 0.207667 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.00821412 | 0.000639106 | 0.000639106 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.00963511 | 0.00152935 | 0.00206149 |
Onchocerca volvulus | 0.0136748 | 0.00406019 | 0.0195515 | |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.00751725 | 0.000202523 | 0.000202523 |
Chlamydia trachomatis | dihydrofolate reductase | 0.84661 | 0.525889 | 0.5 |
Onchocerca volvulus | 0.0111356 | 0.00246937 | 0.011891 | |
Loa Loa (eye worm) | dihydrofolate reductase | 0.84661 | 0.525889 | 0.525889 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.747668 | 0.463902 | 1 |
Brugia malayi | AKH receptor | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | EGF-like domain containing protein | 0.0649717 | 0.0361974 | 0.0361974 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0333934 | 0.0164138 | 0.0178702 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.00875881 | 0.000980354 | 0.00132148 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.00875881 | 0.000980354 | 0.000980354 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Integrin alpha cytoplasmic region family protein | 0.192863 | 0.116321 | 0.116321 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.042721 | 0.0222575 | 0.107179 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0109454 | 0.00235026 | 0.00235026 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.140737 | 0.0836639 | 0.141673 |
Schistosoma mansoni | integrin beta subunit | 0.949808 | 0.590542 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0124708 | 0.0033059 | 0.0033059 |
Echinococcus multilocularis | hypothetical protein | 0.00963511 | 0.00152935 | 0.00206149 |
Schistosoma mansoni | hypothetical protein | 0.0190788 | 0.00744578 | 0.0126084 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0139753 | 0.00424846 | 0.00424846 |
Schistosoma mansoni | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.0649717 | 0.0361974 | 0.0361974 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | 0.0111356 | 0.00246937 | 0.011891 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0501907 | 0.0269372 | 0.0381564 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.00963511 | 0.00152935 | 0.00206149 |
Loa Loa (eye worm) | carboxylesterase | 0.0104634 | 0.00204828 | 0.00204828 |
Trypanosoma brucei | prolyl endopeptidase | 0.00883161 | 0.00102596 | 0.00047546 |
Brugia malayi | Serotonin receptor | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.00935249 | 0.00135229 | 0.00182283 |
Schistosoma mansoni | amine GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0109454 | 0.00235026 | 0.00316806 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.013326 | 0.00384168 | 0.0184993 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | g protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0109454 | 0.00235026 | 0.00316806 |
Brugia malayi | Dopamine receptor protein 1 | 0.013326 | 0.00384168 | 0.00384168 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0285426 | 0.0133748 | 0.0271412 |
Schistosoma mansoni | protein-tyrosine phosphatase non-receptor type nt5 | 0.00963511 | 0.00152935 | 0.00258973 |
Toxoplasma gondii | MAPEG family protein | 0.0473243 | 0.0251414 | 0.0541955 |
Loa Loa (eye worm) | hypothetical protein | 0.0649717 | 0.0361974 | 0.0361974 |
Schistosoma mansoni | non-receptor protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00258973 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0109454 | 0.00235026 | 0.00316806 |
Schistosoma mansoni | amine GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.241537 | 0.146814 | 0.146814 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | thyroid hormone receptor | 0.0109454 | 0.00235026 | 0.00397984 |
Brugia malayi | hypothetical protein | 0.161114 | 0.0964299 | 0.0964299 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Carboxylesterase family protein | 0.0104634 | 0.00204828 | 0.00204828 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0111356 | 0.00246937 | 0.00532304 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0561004 | 0.0306396 | 0.0306396 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.013326 | 0.00384168 | 0.00517842 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.161114 | 0.0964299 | 0.206489 |
Schistosoma mansoni | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00650535 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0111356 | 0.00246937 | 0.00246937 |
Schistosoma mansoni | biogenic amine receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | fibrillin 1 | 0.0649717 | 0.0361974 | 0.0487925 |
Echinococcus granulosus | protein tyrosine phosphatase n9 | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0445164 | 0.0233823 | 0.0315183 |
Brugia malayi | Blistered cuticle protein 3 | 0.0136748 | 0.00406019 | 0.00406019 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.0111356 | 0.00246937 | 0.0033286 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.0104634 | 0.00204828 | 0.00204828 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.00875881 | 0.000980354 | 0.000980354 |
Echinococcus multilocularis | thymidylate synthase | 0.338668 | 0.207667 | 0.279925 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus granulosus | Desert hedgehog protein | 0.0262865 | 0.0119614 | 0.0161234 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.0109454 | 0.00235026 | 0.00235026 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0561004 | 0.0306396 | 0.0413008 |
Brugia malayi | nuclear hormone receptor | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | somatostatin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | histamine h1 receptor | 0.013326 | 0.00384168 | 0.00650535 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | integrin alpha ps | 0.0547908 | 0.0298191 | 0.0401948 |
Echinococcus multilocularis | allatostatin A receptor | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Onchocerca volvulus | Putative organic anion transporter | 0.0111356 | 0.00246937 | 0.011891 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0104634 | 0.00204828 | 0.00204828 |
Schistosoma mansoni | rgs-gaip interacting protein gipc | 0.00963511 | 0.00152935 | 0.00258973 |
Schistosoma mansoni | organic anion transporter | 0.0111356 | 0.00246937 | 0.00418153 |
Onchocerca volvulus | 0.0111356 | 0.00246937 | 0.011891 | |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00258973 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0121072 | 0.00307808 | 0.00414912 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.00963511 | 0.00152935 | 0.00258973 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0109454 | 0.00235026 | 0.00397984 |
Echinococcus granulosus | neuropeptides capa receptor | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | GnHR receptor homolog | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | nuclear hormone receptor | 0.0109454 | 0.00235026 | 0.00397984 |
Onchocerca volvulus | Putative organic anion transporter | 0.0111356 | 0.00246937 | 0.011891 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0109454 | 0.00235026 | 0.00235026 |
Loa Loa (eye worm) | hypothetical protein | 0.0072077 | 0.00000859023 | 0.00000859023 |
Schistosoma mansoni | opsin-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Giardia lamblia | High cysteine protein | 0.0649717 | 0.0361974 | 1 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.00883161 | 0.00102596 | 0.00494042 |
Brugia malayi | Kelch motif family protein | 0.241537 | 0.146814 | 0.146814 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.178105 | 0.107075 | 0.107075 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0121072 | 0.00307808 | 0.00490677 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0109454 | 0.00235026 | 0.0113175 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0561004 | 0.0306396 | 0.0413008 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0136748 | 0.00406019 | 0.00406019 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus granulosus | G protein coupled receptor 139 | 0.013326 | 0.00384168 | 0.00517842 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.00999875 | 0.00175717 | 0.00297552 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0109454 | 0.00235026 | 0.00235026 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.0111356 | 0.00246937 | 0.0033286 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0109454 | 0.00235026 | 0.00397984 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0111356 | 0.00246937 | 0.00246937 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase H | 0.00963511 | 0.00152935 | 0.00206149 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0109454 | 0.00235026 | 0.00397984 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0185966 | 0.00714368 | 0.0689955 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0109454 | 0.00235026 | 0.00397984 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0124708 | 0.0033059 | 0.00559808 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0109454 | 0.00235026 | 0.00397984 |
Trichomonas vaginalis | conserved hypothetical protein | 0.161114 | 0.0964299 | 1 |
Onchocerca volvulus | 0.0136748 | 0.00406019 | 0.0195515 | |
Brugia malayi | prostaglandin transporter | 0.0111356 | 0.00246937 | 0.00246937 |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0121072 | 0.00307808 | 0.00443341 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Brugia malayi | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Trichomonas vaginalis | teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative | 0.0649717 | 0.0361974 | 0.371944 |
Echinococcus granulosus | hypothetical protein | 0.0813085 | 0.0464323 | 0.0625887 |
Brugia malayi | steroid hormone receptor | 0.0109454 | 0.00235026 | 0.00235026 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.338668 | 0.207667 | 0.351654 |
Echinococcus granulosus | neuropeptide receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus granulosus | prolyl endopeptidase | 0.00883161 | 0.00102596 | 0.00138295 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.0136748 | 0.00406019 | 0.00406019 |
Schistosoma mansoni | amine GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0109454 | 0.00235026 | 0.00316806 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0445164 | 0.0233823 | 0.0315183 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.013326 | 0.00384168 | 0.00650535 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0185966 | 0.00714368 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0109454 | 0.00235026 | 0.00316806 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Brugia malayi | hypothetical protein | 0.241537 | 0.146814 | 0.146814 |
Onchocerca volvulus | 0.0649717 | 0.0361974 | 0.174305 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.00999875 | 0.00175717 | 0.00236859 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0185966 | 0.00714368 | 0.00714368 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Echinococcus multilocularis | g-protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Loa Loa (eye worm) | hypothetical protein | 0.00963511 | 0.00152935 | 0.00152935 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.013326 | 0.00384168 | 0.00384168 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.00963511 | 0.00152935 | 0.00152935 |
Giardia lamblia | Protein tyrosine phosphatase | 0.00963511 | 0.00152935 | 0.00508134 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | Putative organic anion transporter | 0.0111356 | 0.00246937 | 0.011891 |
Echinococcus multilocularis | acetylcholinesterase | 0.0104634 | 0.00204828 | 0.00276099 |
Schistosoma mansoni | myosin xvIII | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.00999875 | 0.00175717 | 0.00297552 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.013326 | 0.00384168 | 0.00384168 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus granulosus | orexin receptor type 2 | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | thyroid hormone receptor | 0.0109454 | 0.00235026 | 0.00397984 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Brugia malayi | sulfakinin receptor protein | 0.013326 | 0.00384168 | 0.00384168 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.013326 | 0.00384168 | 0.00650535 |
Loa Loa (eye worm) | hypothetical protein | 0.00935249 | 0.00135229 | 0.00135229 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0109454 | 0.00235026 | 0.00397984 |
Giardia lamblia | Tenascin-37 | 0.0649717 | 0.0361974 | 1 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0473243 | 0.0251414 | 0.0338895 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0187359 | 0.00723096 | 0.0122446 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.00999875 | 0.00175717 | 0.00297552 |
Schistosoma mansoni | hypothetical protein | 0.013326 | 0.00384168 | 0.00650535 |
Schistosoma mansoni | hypothetical protein | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.013326 | 0.00384168 | 0.00517842 |
Echinococcus multilocularis | serotonin receptor | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0109454 | 0.00235026 | 0.00397984 |
Brugia malayi | ecdysteroid receptor | 0.0369788 | 0.01866 | 0.01866 |
Loa Loa (eye worm) | hypothetical protein | 0.0369788 | 0.01866 | 0.01866 |
Toxoplasma gondii | hypothetical protein | 0.00972723 | 0.00158707 | 0.00342112 |
Onchocerca volvulus | 4.1 G protein, putative homolog | 0.00963511 | 0.00152935 | 0.00736444 |
Echinococcus granulosus | g protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0104634 | 0.00204828 | 0.00346848 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0109454 | 0.00235026 | 0.00316806 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.013326 | 0.00384168 | 0.00650535 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.00963511 | 0.00152935 | 0.00206149 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.013326 | 0.00384168 | 0.0184993 |
Loa Loa (eye worm) | hypothetical protein | 0.0111356 | 0.00246937 | 0.00246937 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.00935249 | 0.00135229 | 0.00182283 |
Brugia malayi | EGF-like domain containing protein | 0.0649717 | 0.0361974 | 0.0361974 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.0136748 | 0.00406019 | 0.0195515 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0311102 | 0.0149834 | 0.0280879 |
Loa Loa (eye worm) | protein-tyrosine-phosphatase | 0.00963511 | 0.00152935 | 0.00152935 |
Onchocerca volvulus | 0.013326 | 0.00384168 | 0.0184993 | |
Echinococcus multilocularis | g protein coupled receptor | 0.013326 | 0.00384168 | 0.00517842 |
Onchocerca volvulus | 0.00963511 | 0.00152935 | 0.00736444 | |
Echinococcus granulosus | integrin beta 2 | 1.19134 | 0.741863 | 1 |
Brugia malayi | dihydrofolate reductase family protein | 0.84661 | 0.525889 | 0.525889 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antiinflammatory activity measured by using McKenzie-Stoughton human vasoconstrictor assay | ChEMBL. | 3783574 | |
Activity (binding) | Inhibition of mouse brain MAOA | ChEMBL. | 18834112 | |
Activity (functional) | TP_TRANSPORTER: transepithelial transport in MDR1-expressing LLC-PK1 cells | ChEMBL. | 14661924 | |
Activity (functional) | = 57 % | Antiinflammatory activity against oxazolone-induced atopic dermatitis in nude mouse assessed as decrease in transepidermal water loss at 0.01 % administered topically bid simultaneously with oxazolone qd for 10 days following 5 days post-oxazolone challenge relative to control | ChEMBL. | 20547454 |
CL (ADMET) | = 2.8 ml/min.kg | Total body clearance in human | ChEMBL. | 19445515 |
CL_renal (ADMET) | = 0.14 ml/min.kg | Renal clearance in human | ChEMBL. | 19445515 |
Fu (ADMET) | = 0.36 | Unbound fraction (plasma) | ChEMBL. | 14971904 |
IC50 (binding) | DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Leishmania donovani | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Trypanosoma brucei | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase PKCalpha enzyme inhibition (substrate: Histone) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Leishmania mexicana | ChEMBL. | 20185316 | |
IC50 (functional) | Antimicrobial activity against Trypanosoma brucei rhodesiense | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Chemokine CXCR1 (IL-8A) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Cryptosporidium parvum | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Trichomonas vaginalis | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Trypanosoma cruzi | ChEMBL. | 20185316 | |
IC50 (functional) | Antimicrobial activity against Trypanosoma brucei brucei | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Toxoplasma gondii | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Plasmodium falciparum | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Leishmania major | ChEMBL. | 20185316 | |
IC50 (functional) | Antimicrobial activity against Entamoeba histolytica | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) | ChEMBL. | No reference | |
IC50 (functional) | Antimicrobial activity against Leishmania infantum | ChEMBL. | 20185316 | |
IC50 (binding) | DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Calcitonin radioligand binding (ligand: [125I] Calcitonin (salmon)) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) | ChEMBL. | No reference | |
IC50 (binding) | DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) | ChEMBL. | No reference | |
IC50 (functional) | = -5 | Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay | ChEMBL. | 19734910 |
IC50 (functional) | = -4.9 | Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay | ChEMBL. | 19734910 |
IC50 (functional) | = -4.9 | Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay | ChEMBL. | 19734910 |
IC50 (functional) | = -4.9 | Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay | ChEMBL. | 19734910 |
IC50 (functional) | = -4.8 | Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay | ChEMBL. | 19734910 |
IC50 (binding) | = 0.007735 uM | DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) | ChEMBL. | No reference |
IC50 (functional) | = 1 uM | Anti-inflammatory activity in Homo sapiens (human) whole blood assessed inhibition of LPS-induced TNF-alpha production treated 30 min before LPS challenge measured after 5 hr | ChEMBL. | No reference |
IC50 (functional) | > 29.9 uM | PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) | ChEMBL. | No reference |
Inhibition (functional) | = 46 % | Antiarthritic activity in DBA/1J mouse collagen-induced arthritis model assessed as reduction in paw swelling at 5 mg/kg, po administered once daily for 49 days starting from onset of disease | ChEMBL. | 25111439 |
Inhibition (ADMET) | = 76.17449754 % | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | ChEMBL. | 23571415 |
Inhibition (functional) | = 87 % | Anti-inflammatory activity in Homo sapiens (human) whole blood assessed inhibition of LPS-induced TNF-alpha production at 10 uM treated 30 min before LPS challenge measured after 5 hr | ChEMBL. | No reference |
Inhibition (ADMET) | = 102.6935731 % | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | ChEMBL. | 23571415 |
Ki (binding) | DRUGMATRIX: Calcitonin radioligand binding (ligand: [125I] Calcitonin (salmon)) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Chemokine CXCR1 (IL-8A) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase PKCalpha enzyme inhibition (substrate: Histone) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) | ChEMBL. | No reference | |
Ki (binding) | DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) | ChEMBL. | No reference | |
Ki (binding) | = 0.003516 uM | DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) | ChEMBL. | No reference |
log Kp (ADMET) | = -7.35 | Permeability coefficient in human skin | ChEMBL. | 17827020 |
log Kp (ADMET) | = -7.17 | Permeability across human Skin | ChEMBL. | 17300161 |
log Pe (ADMET) | = -5.84 | Permeability across PAMPA membrane after 7 hrs | ChEMBL. | 17300161 |
LogP | = 2.01 | Partition coefficient, log P of the compound | ChEMBL. | 17300161 |
pKa | NA 0 | Dissociation constant (pKa) | ChEMBL. | 14971904 |
Potency (functional) | = 0.8 | Potency relative to fluocinolone 16,17-acetonide in the human vasoconstictor test | ChEMBL. | 6827553 |
Potency (functional) | 0.0014 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0049 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0049 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0052 uM | PubChem BioAssay. Nrf2 qHTS screen for inhibitors: Nrf2 A549 ARE-Fluc Confirmation Assay for Hit Validation. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.01 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0107 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0164 uM | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] | ChEMBL. | No reference |
Potency (functional) | 0.0211 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0376 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0891 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 1.9953 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of vitamin D receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 3.0131 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Potency (functional) | 3.6626 uM | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 5.0119 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 17.7828 uM | PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 27.306 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
RBA (binding) | = 0.1 | Relative binding affinity for progestin receptor of uterus of rabbit at 24 hr | ChEMBL. | 2897467 |
RBA (binding) | = 0.1 | Relative binding affinity for androgen receptor of prostate of rat at 2 hr | ChEMBL. | 2897467 |
RBA (binding) | = 17 | Relative binding affinity for mineralocorticoid receptor of rat kidney at 24 hr | ChEMBL. | 2897467 |
Relative activity (functional) | = 106 % | Glucocorticoid induced Tyrosine Aminotransferase activity relative to dexamethasone | ChEMBL. | 2897467 |
Vdss (ADMET) | = 1.32 l kg-1 | Observed volume of distribution | ChEMBL. | 14971904 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | ||
Plasmodium falciparum | ChEMBL23 | 19734910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
67 literature references were collected for this gene.