Detailed information for compound 266846

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 522.542 | Formula: C26H34O11
  • H donors: 1 H acceptors: 5 LogP: 1.97 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)O[C@H]1C[C@](C)(O)C23[C@]([C@H]1OC(=O)C)(C)[C@@H](OC(=O)c1ccco1)CC([C@H]3OC(=O)C)C(O2)(C)C
  • InChi: 1S/C26H34O11/c1-13(27)33-18-12-24(6,31)26-20(34-14(2)28)16(23(4,5)37-26)11-19(25(26,7)21(18)35-15(3)29)36-22(30)17-9-8-10-32-17/h8-10,16,18-21,31H,11-12H2,1-7H3/t16?,18-,19-,20+,21-,24-,25+,26?/m0/s1
  • InChiKey: YYWVLZFGYSCNIJ-IYHOFXMLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0215 0.2607 0.4518
Brugia malayi G protein-coupled receptor 0.0215 0.2607 0.4527
Mycobacterium ulcerans hypothetical protein 0.0031 0.0109 0.0141
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0095 0.0165
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) neuropeptide F receptor 0.0215 0.2607 0.4527
Treponema pallidum flavodoxin 0.0171 0.2011 1
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0095 0.0068
Echinococcus multilocularis tissue type plasminogen activator 0.0172 0.202 0.202
Echinococcus multilocularis heat shock protein 0.0033 0.0133 0.0133
Echinococcus multilocularis protein jagged 2 0.0027 0.0057 0.0057
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0029 0.005
Loa Loa (eye worm) hypothetical protein 0.0063 0.0551 0.0957
Onchocerca volvulus 0.0215 0.2607 0.4518
Echinococcus multilocularis fibrillin 1 0.0071 0.0651 0.0651
Schistosoma mansoni opsin-like receptor 0.0215 0.2607 0.2607
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0051 0.038 0.1407
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0215 0.2607 0.2607
Brugia malayi beta-lactamase family protein 0.0031 0.0109 0.019
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0133 0.0493
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0057 0.0057
Leishmania major hypothetical protein, conserved 0.0172 0.202 0.3508
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0095 0.0165
Schistosoma mansoni nuclear hormone receptor 0.003 0.0095 0.0095
Echinococcus granulosus biogenic amine 5HT receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0031 0.0109 0.019
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0215 0.2607 0.4527
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0043 0.0043
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0063 0.0551 0.0551
Echinococcus granulosus 7tm_1 domain containing protein 0.0215 0.2607 0.2607
Onchocerca volvulus 0.0215 0.2607 0.4518
Chlamydia trachomatis sulfite reductase 0.0276 0.3437 1
Brugia malayi beta-lactamase family protein 0.0031 0.0109 0.019
Treponema pallidum heat shock protein 90 0.0026 0.0043 0.0073
Onchocerca volvulus 0.0215 0.2607 0.4518
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni neuropeptide receptor 0.0215 0.2607 0.2607
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Brugia malayi RNA, U transporter 1 0.0088 0.0887 0.154
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0051 0.038 0.038
Echinococcus multilocularis g protein coupled receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0447 0.5758 1
Onchocerca volvulus Arrow homolog 0.0071 0.0651 0.1052
Schistosoma mansoni diflavin oxidoreductase 0.0222 0.2701 0.2701
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0095 0.0095
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Schistosoma mansoni heat shock protein 0.0033 0.0133 0.0133
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0215 0.2607 0.4527
Schistosoma mansoni amine GPCR 0.0215 0.2607 0.2607
Mycobacterium ulcerans lipase LipD 0.0031 0.0109 0.0141
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0051 0.038 0.066
Schistosoma mansoni alpha-1 adrenergic receptor 0.0215 0.2607 0.2607
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Entamoeba histolytica type A flavoprotein, putative 0.0171 0.2011 1
Echinococcus granulosus heat shock protein 90 0.0026 0.0043 0.0043
Onchocerca volvulus 0.0031 0.0109 0.0093
Giardia lamblia Nitric oxide synthase, inducible 0.0396 0.5068 1
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Echinococcus multilocularis somatostatin receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0111 0.0111
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Echinococcus multilocularis notch 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0033 0.014 0.0243
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0029 0.0106
Onchocerca volvulus 0.0063 0.0551 0.0876
Echinococcus granulosus dro:myosuppressin receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0215 0.2607 0.2607
Echinococcus granulosus importin subunit beta 1 0.0031 0.0111 0.0111
Echinococcus granulosus snurportin 1 0.0331 0.4181 0.4181
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0447 0.5758 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Mycobacterium tuberculosis Probable monooxygenase 0.0051 0.038 0.1504
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Loa Loa (eye worm) notch protein 0.0027 0.0057 0.0099
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0215 0.2607 0.2607
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0215 0.2607 0.4527
Echinococcus granulosus g protein coupled receptor 0.0215 0.2607 0.2607
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0095 0.0095
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0031 0.0109 0.0346
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0133 0.0231
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0095 0.0095
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0215 0.2607 0.4527
Giardia lamblia High cysteine protein 0.0027 0.0057 0.0112
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0111 0.0411
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0095 0.0165
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0095 0.0095
Toxoplasma gondii flavodoxin domain-containing protein 0.0222 0.2701 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0651 0.113
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0215 0.2607 0.2607
Onchocerca volvulus 0.0215 0.2607 0.4518
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Brugia malayi AKH receptor 0.0215 0.2607 0.4527
Echinococcus multilocularis Tolloid protein 1 0.0071 0.0651 0.0651
Echinococcus multilocularis G-protein coupled receptor, putative 0.0215 0.2607 0.2607
Echinococcus multilocularis fibropellin Ia 0.0027 0.0057 0.0057
Onchocerca volvulus Bile acid receptor homolog 0.0328 0.4147 0.7248
Brugia malayi ecdysteroid receptor 0.0328 0.4147 0.7203
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0043 0.0075
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0032 0.0055
Brugia malayi G-protein coupled receptor 0.0215 0.2607 0.4527
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0284 0.0446
Mycobacterium ulcerans oxidoreductase 0.0051 0.038 0.0614
Onchocerca volvulus 0.0172 0.202 0.3479
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0057 0.0099
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0133 0.0231
Leishmania major hypothetical protein, conserved 0.0171 0.2011 0.3493
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0447 0.5758 1
Schistosoma mansoni importin beta-1 0.0031 0.0111 0.0111
Brugia malayi GnHR receptor homolog 0.0215 0.2607 0.4527
Plasmodium vivax hypothetical protein, conserved 0.0171 0.2011 0.3493
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0215 0.2607 0.2607
Echinococcus granulosus orexin receptor type 2 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni hypothetical protein 0.0215 0.2607 0.2607
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Echinococcus granulosus protein jagged 1 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni opsin-like receptor 0.0215 0.2607 0.2607
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0109 0.019
Brugia malayi Dopamine receptor protein 1 0.0215 0.2607 0.4527
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0172 0.202 0.3508
Brugia malayi Trypsin family protein 0.0063 0.0551 0.0957
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0057 0.0099
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Loa Loa (eye worm) hypothetical protein 0.0071 0.0651 0.113
Mycobacterium tuberculosis Conserved protein 0.0031 0.0109 0.0346
Onchocerca volvulus 0.0054 0.0429 0.066
Echinococcus multilocularis neuropeptides capa receptor 0.0215 0.2607 0.2607
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0063 0.0551 0.0957
Echinococcus multilocularis enteropeptidase 0.0063 0.0551 0.0551
Echinococcus granulosus tm gpcr rhodopsin 0.0215 0.2607 0.2607
Echinococcus granulosus heat shock protein 90 0.0033 0.0133 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0057 0.0099
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0071 0.0651 0.113
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0133 0.0662
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0215 0.2607 0.2607
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0215 0.2607 0.2607
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0043 0.0075
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0043 0.0085
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0063 0.0551 0.0551
Schistosoma mansoni histamine h1 receptor 0.0215 0.2607 0.2607
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0051 0.038 0.1504
Echinococcus multilocularis neuropeptide s receptor 0.0215 0.2607 0.2607
Brugia malayi Endoplasmin precursor 0.0033 0.0133 0.0231
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0095 0.0165
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Onchocerca volvulus 0.0215 0.2607 0.4518
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0057 0.0057
Echinococcus granulosus notch 0.0027 0.0057 0.0057
Onchocerca volvulus 0.0215 0.2607 0.4518
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0051 0.038 0.0614
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0447 0.5758 1
Brugia malayi Trypsin family protein 0.0063 0.0551 0.0957
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0171 0.2011 0.3493
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0032 0.0055
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0171 0.2011 0.3493
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis sex peptide receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) G-protein coupled receptor 0.0215 0.2607 0.4527
Schistosoma mansoni adenoreceptor 0.0215 0.2607 0.2607
Onchocerca volvulus 0.0063 0.0551 0.0876
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0447 0.5758 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0095 0.0095
Mycobacterium tuberculosis Probable lipase LipE 0.0031 0.0109 0.0346
Brugia malayi putative neuropeptide receptor 0.0215 0.2607 0.4527
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Leishmania major nitrate reductase, putative 0.0051 0.038 0.066
Plasmodium falciparum ferredoxin--NADP reductase 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) TYRA-2 protein 0.0215 0.2607 0.4527
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Schistosoma mansoni laminin gamma-3 chain 0.0027 0.0057 0.0057
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0051 0.038 0.066
Echinococcus granulosus tumor protein p63 0.0372 0.4738 0.4738
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0095 0.0095
Plasmodium falciparum cysteine repeat modular protein 1 0.0172 0.202 0.3508
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0095 0.0095
Leishmania major NADH-dependent fumarate reductase-like protein 0.0051 0.038 0.066
Echinococcus granulosus peptide allatostatin:somatostatin 0.0215 0.2607 0.2607
Trypanosoma brucei NADH-dependent fumarate reductase 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus protein jagged 1 0.0027 0.0057 0.0057
Brugia malayi Cadherin domain containing protein 0.0027 0.0057 0.0099
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0051 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Schistosoma mansoni neuropeptide F-like receptor 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0043 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Echinococcus granulosus alpha 1A adrenergic receptor 0.0215 0.2607 0.2607
Brugia malayi neuropeptide F receptor 0.0215 0.2607 0.4527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0095 0.0165
Schistosoma mansoni septate junction protein 0.0027 0.0057 0.0057
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0095 0.0095
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0284 0.0494
Mycobacterium ulcerans esterase/lipase LipP 0.0031 0.0109 0.0141
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0551 0.0551
Onchocerca volvulus 0.0063 0.0551 0.0876
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Echinococcus multilocularis dro:myosuppressin receptor 0.0215 0.2607 0.2607
Brugia malayi flavodoxin family protein 0.0447 0.5758 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0095 0.0165
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0095 0.0095
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Echinococcus multilocularis heat shock protein 90 0.0033 0.0133 0.0133
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0067 0.0116
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0215 0.2607 0.2607
Schistosoma mansoni heat shock protein 0.0033 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) hypothetical protein 0.0028 0.0067 0.0116
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0215 0.2607 0.2607
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0032 0.0055
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0051 0.038 0.0614
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0043 0.0075
Treponema pallidum ferredoxin-NADP(+) reductase subunit alpha 0.0051 0.038 0.1773
Brugia malayi Tachykinin-like peptides receptor 99D 0.0215 0.2607 0.4527
Schistosoma mansoni biogenic amine (5HT) receptor 0.0215 0.2607 0.2607
Leishmania major NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Schistosoma mansoni cytochrome P450 reductase 0.0447 0.5758 0.5758
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0095 0.0165
Mycobacterium tuberculosis Probable hydrolase 0.0031 0.0109 0.0346
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0057 0.0057
Schistosoma mansoni notch 0.0027 0.0057 0.0057
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0215 0.2607 0.2607
Brugia malayi polk-prov protein 0.0033 0.014 0.0243
Brugia malayi Fibulin-1 precursor 0.0071 0.0651 0.113
Echinococcus multilocularis neuropeptide receptor 0.0215 0.2607 0.2607
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0031 0.0109 0.0346
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0031 0.0109 0.019
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0443 0.57 0.57
Echinococcus granulosus neurogenic locus notch protein 4 0.0027 0.0057 0.0057
Echinococcus granulosus transmembrane protease serine 3 0.0063 0.0551 0.0551
Echinococcus multilocularis neuropeptide receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0063 0.0551 0.0957
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0067 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0057 0.0099
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0215 0.2607 0.2607
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0172 0.202 0.3508
Loa Loa (eye worm) hypothetical protein 0.0031 0.0111 0.0193
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0197 0.2367 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0031 0.0109 0.0346
Echinococcus multilocularis cytochrome b5 reductase 4 0.0051 0.038 0.038
Brugia malayi G protein-coupled receptor F59B2.13 0.0215 0.2607 0.4527
Echinococcus granulosus cytochrome b5 reductase 4 0.0051 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus sex peptide receptor 0.0215 0.2607 0.2607
Brugia malayi Protein kinase domain containing protein 0.0172 0.202 0.3508
Schistosoma mansoni cell polarity protein 0.0027 0.0057 0.0057
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0215 0.2607 0.2607
Echinococcus multilocularis protein jagged 1 0.0027 0.0057 0.0057
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0171 0.2011 0.3493
Loa Loa (eye worm) melatonin receptor type 1A 0.0215 0.2607 0.4527
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0171 0.2011 0.3493
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Plasmodium vivax flavodoxin domain containing protein 0.0396 0.5068 0.8802
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0215 0.2607 0.2607
Leishmania major cytochrome P450 reductase, putative 0.0396 0.5068 0.8802
Onchocerca volvulus 0.0215 0.2607 0.4518
Echinococcus granulosus somatostatin receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0057 0.0057
Onchocerca volvulus 0.0443 0.57 1
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0171 0.2011 0.3493
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0133 0.0662
Schistosoma mansoni neuropeptide receptor 0.0215 0.2607 0.2607
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0095 0.0068
Echinococcus granulosus g-protein coupled receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Schistosoma mansoni growth hormone secretagogue receptor 0.0215 0.2607 0.2607
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Echinococcus multilocularis fmrfamide receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0071 0.0651 0.113
Echinococcus granulosus tachykinin peptides receptor 99D 0.0215 0.2607 0.2607
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0095 0.0095
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0215 0.2607 0.2607
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Brugia malayi nuclear receptor NHR-88 0.003 0.0095 0.0165
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0051 0.038 0.066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.019
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0447 0.5758 0.5758
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0063 0.0551 0.0551
Trypanosoma brucei unspecified product 0.0037 0.0189 0.0328
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0095 0.0165
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0109 0.019
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0095 0.0165
Loa Loa (eye worm) FAD binding domain-containing protein 0.0276 0.3437 0.5969
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0051 0.038 0.066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0095 0.0165
Brugia malayi Trypsin family protein 0.0443 0.57 0.99
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Echinococcus granulosus neural cadherin 0.0027 0.0057 0.0057
Echinococcus granulosus dna polymerase kappa 0.0044 0.0284 0.0284
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0095 0.0165
Echinococcus multilocularis beta LACTamase domain containing family member 0.0031 0.0109 0.0109
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0215 0.2607 0.2607
Brugia malayi hypothetical protein 0.0028 0.0067 0.0116
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0109 0.019
Schistosoma mansoni biogenic amine receptor 0.0215 0.2607 0.2607
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0215 0.2607 0.2607
Schistosoma mansoni coup transcription factor 0.003 0.0095 0.0095
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0051 0.038 0.1504
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Echinococcus granulosus allatostatin A receptor 0.0215 0.2607 0.2607
Brugia malayi hypothetical protein 0.0063 0.0551 0.0957
Trypanosoma cruzi oxidoreductase-protein, putative 0.0051 0.038 0.066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0095 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Giardia lamblia Grp94/Hsp90 0.0026 0.0043 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Giardia lamblia Hypothetical protein 0.0396 0.5068 1
Schistosoma mansoni hypothetical protein 0.0331 0.4181 0.4181
Schistosoma mansoni amine GPCR 0.0215 0.2607 0.2607
Echinococcus multilocularis serotonin receptor 0.0215 0.2607 0.2607
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0071 0.0651 0.113
Echinococcus multilocularis g-protein coupled receptor 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Echinococcus granulosus cytochrome b5 reductase 4 0.0051 0.038 0.038
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0029 0.005
Brugia malayi diaphorase 0.0051 0.038 0.066
Echinococcus multilocularis Mastin 0.0063 0.0551 0.0551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0095 0.0165
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma brucei NADH-dependent fumarate reductase 0.0051 0.038 0.066
Brugia malayi flavodoxin family protein 0.0171 0.2011 0.3493
Trypanosoma cruzi nitrate reductase, putative 0.0051 0.038 0.066
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0447 0.5758 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0551 0.0957
Plasmodium vivax endoplasmin, putative 0.0033 0.0133 0.0231
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0284 0.0284
Trypanosoma cruzi p450 reductase, putative 0.0051 0.038 0.066
Mycobacterium ulcerans electron transfer protein FdxB 0.0051 0.038 0.0614
Toxoplasma gondii flavodoxin domain-containing protein 0.0222 0.2701 1
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0133 0.0231
Entamoeba histolytica type A flavoprotein, putative 0.0171 0.2011 1
Onchocerca volvulus 0.0031 0.0109 0.0093
Schistosoma mansoni notch 0.0027 0.0057 0.0057
Schistosoma mansoni neuropeptide f receptor 76f 0.0215 0.2607 0.2607
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0109 0.019
Loa Loa (eye worm) Notch2 0.0027 0.0057 0.0099
Schistosoma mansoni thyroid hormone receptor 0.003 0.0095 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0095 0.0095
Echinococcus granulosus neuropeptides capa receptor 0.0215 0.2607 0.2607
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0651 0.113
Onchocerca volvulus 0.0215 0.2607 0.4518
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0284 0.0446
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0133 0.0231
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0133 0.0263
Echinococcus granulosus tm gpcr rhodopsin 0.0215 0.2607 0.2607
Echinococcus multilocularis transmembrane protease serine 3 0.0063 0.0551 0.0551
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0893 0.155
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0095 0.0165
Schistosoma mansoni neuropeptide F-like receptor 0.0215 0.2607 0.2607
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0133 0.0493
Entamoeba histolytica type A flavoprotein, putative 0.0171 0.2011 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0095 0.0095
Echinococcus multilocularis methionine synthase reductase 0.0276 0.3437 0.3437
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0067 0.0116
Mycobacterium tuberculosis Conserved protein 0.0031 0.0109 0.0346
Loa Loa (eye worm) hypothetical protein 0.0071 0.0651 0.113
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma brucei nitrate reductase, putative 0.0051 0.038 0.066
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0095 0.0095
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0095 0.0165
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0447 0.5758 1
Schistosoma mansoni opsin-like receptor 0.0215 0.2607 0.2607
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Entamoeba histolytica type A flavoprotein, putative 0.0171 0.2011 1
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Giardia lamblia Flavohemoprotein lateral transfer candidate 0.0051 0.038 0.075
Loa Loa (eye worm) hypothetical protein 0.0089 0.0893 0.155
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0095 0.0165
Echinococcus multilocularis neuropeptides capa receptor 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0215 0.2607 0.2607
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0095 0.0095
Echinococcus granulosus endoplasmin 0.0026 0.0043 0.0043
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Loa Loa (eye worm) G-protein coupled receptor 0.0215 0.2607 0.4527
Echinococcus granulosus neuropeptides capa receptor 0.0215 0.2607 0.2607
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Onchocerca volvulus 0.0215 0.2607 0.4518
Loa Loa (eye worm) hypothetical protein 0.0063 0.0551 0.0957
Leishmania major NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Onchocerca volvulus 0.0215 0.2607 0.4518
Echinococcus granulosus serotonin receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis tumor protein p63 0.0372 0.4738 0.4738
Echinococcus multilocularis slit 2 protein 0.0027 0.0057 0.0057
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Mycobacterium tuberculosis Probable oxidoreductase 0.0051 0.038 0.1504
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0109 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Toxoplasma gondii kringle domain-containing protein 0.0172 0.202 0.7479
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0171 0.2011 0.3493
Echinococcus granulosus Mastin 0.0063 0.0551 0.0551
Echinococcus granulosus fibropellin Ia 0.0027 0.0057 0.0057
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Echinococcus granulosus g protein coupled receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis laminin 0.0071 0.0651 0.0651
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0893 0.0893
Onchocerca volvulus 0.0379 0.484 0.8475
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Schistosoma mansoni hypothetical protein 0.0172 0.202 0.202
Onchocerca volvulus 0.0215 0.2607 0.4518
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0111 0.0193
Leishmania major importin beta-1 subunit, putative 0.0025 0.0032 0.0055
Brugia malayi Trypsin family protein 0.0063 0.0551 0.0957
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Echinococcus granulosus beta LACTamase domain containing family member 0.0031 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Schistosoma mansoni slit 0.0027 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0095 0.0165
Onchocerca volvulus 0.0089 0.0893 0.1481
Echinococcus granulosus protein jagged 2 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Brugia malayi heat shock protein 90 0.0033 0.0133 0.0231
Onchocerca volvulus 0.0215 0.2607 0.4518
Onchocerca volvulus Neuropeptide F receptor homolog 0.0215 0.2607 0.4518
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0095 0.0165
Echinococcus granulosus Tolloid protein 1 0.0071 0.0651 0.0651
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0133 0.0231
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0284 0.0494
Loa Loa (eye worm) flavodoxin family protein 0.0171 0.2011 0.3493
Leishmania major NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Loa Loa (eye worm) FAD binding domain-containing protein 0.0447 0.5758 1
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0447 0.5758 0.5758
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0215 0.2607 0.2607
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Onchocerca volvulus 0.0031 0.0109 0.0093
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0067 0.0248
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.019
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0067 0.0116
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0447 0.5758 0.5758
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0133 0.0231
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0551 0.0551
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0331 0.4181 0.7262
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0109 0.019
Echinococcus multilocularis neuropeptide receptor A26 0.0215 0.2607 0.2607
Schistosoma mansoni neuropeptide receptor 0.0215 0.2607 0.2607
Echinococcus granulosus neuropeptide Y receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0095 0.0095
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0027 0.0057 0.0099
Mycobacterium ulcerans oxygenase 0.0051 0.038 0.0614
Leishmania major hypothetical protein, conserved 0.0031 0.0109 0.019
Loa Loa (eye worm) trypsin family protein 0.0063 0.0551 0.0957
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0215 0.2607 0.4527
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0063 0.0551 0.0957
Echinococcus granulosus slit 2 protein 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni endoplasmin 0.0033 0.0133 0.0133
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0043 0.0075
Loa Loa (eye worm) hypothetical protein 0.0071 0.0651 0.113
Echinococcus granulosus neuropeptide receptor A26 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0447 0.5758 1
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Schistosoma mansoni hypothetical protein 0.0063 0.0551 0.0551
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0027 0.0057 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0051 0.038 0.1407
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0031 0.0109 0.0141
Entamoeba histolytica hypothetical protein 0.0025 0.0029 0.0142
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0215 0.2607 0.2607
Leishmania major hypothetical protein, conserved 0.0028 0.0067 0.0116
Schistosoma mansoni cytochrome B5 0.0051 0.038 0.038
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0095 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0133 0.0231
Echinococcus multilocularis fmrfamide receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.019
Echinococcus granulosus 7TM GPCR rhodopsin 0.0215 0.2607 0.2607
Brugia malayi Dopamine receptor 0.0215 0.2607 0.4527
Echinococcus granulosus heat shock protein 0.0033 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) hypothetical protein 0.0054 0.0429 0.0746
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Brugia malayi steroid hormone receptor 0.003 0.0095 0.0165
Schistosoma mansoni notch 0.0027 0.0057 0.0057
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0215 0.2607 0.4527
Schistosoma mansoni amine GPCR 0.0215 0.2607 0.2607
Brugia malayi nuclear hormone receptor 0.003 0.0095 0.0165
Brugia malayi Delta serrate ligand family protein 0.0027 0.0057 0.0099
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0215 0.2607 0.2607
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Trypanosoma brucei oxidoreductase-protein, putative 0.0051 0.038 0.066
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0284 0.0494
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Brugia malayi RE15519p 0.0215 0.2607 0.4527
Schistosoma mansoni NADPH flavin oxidoreductase 0.0225 0.2747 0.2747
Trichomonas vaginalis esterase, putative 0.0031 0.0109 0.019
Echinococcus granulosus fmrfamide receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0429 0.0429
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Leishmania major cytochrome-b5 reductase, putative 0.0051 0.038 0.066
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0071 0.0651 0.113
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Mycobacterium leprae Probable lipase LipE 0.0031 0.0109 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Echinococcus multilocularis serotonin receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus multilocularis microtubule associated protein 2 0.076 1 1
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0095 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.014 0.0243
Echinococcus granulosus neuropeptide FF receptor 2 0.0215 0.2607 0.2607
Schistosoma mansoni egf-like domain protein 0.0071 0.0651 0.0651
Echinococcus granulosus methionine synthase reductase 0.0276 0.3437 0.3437
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0043 0.1794
Brugia malayi Dopamine receptor protein 2 0.0215 0.2607 0.4527
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0095 0.0095
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0893 0.0893
Echinococcus multilocularis heat shock protein 90 0.0026 0.0043 0.0043
Trichomonas vaginalis sulfite reductase, putative 0.0447 0.5758 1
Echinococcus granulosus laminin 0.0071 0.0651 0.0651
Schistosoma mansoni thyroid hormone receptor 0.003 0.0095 0.0095
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0893 0.0893
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0029 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0133 0.0231
Echinococcus multilocularis neurogenic locus notch protein 4 0.0027 0.0057 0.0057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0133 0.0231
Schistosoma mansoni notch 0.0027 0.0057 0.0057
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0109 0.019
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0043 1
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Onchocerca volvulus 0.0215 0.2607 0.4518
Echinococcus multilocularis fat cadherin tumor suppressor 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Brugia malayi Trypsin-like protease protein 5 0.0063 0.0551 0.0957
Echinococcus granulosus glycoprotein Antigen 5 0.0063 0.0551 0.0551
Echinococcus granulosus FTZ F1 alpha 0.003 0.0095 0.0095
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0095 0.0095
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0189 0.0328
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Echinococcus multilocularis g protein coupled receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Echinococcus granulosus neuropeptide s receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0095 0.0165
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0095 0.0095
Plasmodium falciparum nitric oxide synthase, putative 0.0447 0.5758 1
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0284 0.0494
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0063 0.0551 0.0551
Brugia malayi G-protein coupled receptor 0.0215 0.2607 0.4527
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0215 0.2607 0.2607
Echinococcus granulosus tm gpcr rhodopsin 0.0215 0.2607 0.2607
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0443 0.57 0.57
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0215 0.2607 0.2607
Mycobacterium ulcerans hypothetical protein 0.0063 0.0551 0.0912
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0215 0.2607 0.2607
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0215 0.2607 0.2607
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0396 0.5068 0.8802
Mycobacterium tuberculosis Possible oxygenase 0.0051 0.038 0.1504
Loa Loa (eye worm) endoplasmin 0.0033 0.0133 0.0231
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0095 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0057 0.0057
Leishmania major reductase, putative 0.0051 0.038 0.066
Schistosoma mansoni amine GPCR 0.0215 0.2607 0.2607
Plasmodium falciparum heat shock protein 90 0.0033 0.0133 0.0231
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0651 0.2409
Echinococcus granulosus hypothetical protein 0.0215 0.2607 0.2607
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0551 0.0551
Schistosoma mansoni neuropeptide receptor 0.0215 0.2607 0.2607
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Mycobacterium tuberculosis Probable esterase LipL 0.0031 0.0109 0.0346
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.019
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Brugia malayi Muscle positioning protein 4 0.0027 0.0057 0.0099
Schistosoma mansoni biogenic amine receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Brugia malayi notch-like transmembrane receptor 0.0027 0.0057 0.0099
Leishmania major oxidoreductase-like protein 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0443 0.57 0.99
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0043 0.0025
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0171 0.2011 0.3493
Loa Loa (eye worm) beta-lactamase 0.0031 0.0109 0.019
Echinococcus multilocularis neural cadherin 0.0027 0.0057 0.0057
Onchocerca volvulus 0.0215 0.2607 0.4518
Schistosoma mansoni hypothetical protein 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0165
Echinococcus multilocularis g protein coupled receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Toxoplasma gondii EGF family domain-containing protein 0.0027 0.0057 0.021
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Echinococcus granulosus neurogenic locus protein delta 0.0027 0.0057 0.0057
Echinococcus multilocularis neuropeptide FF receptor 2 0.0215 0.2607 0.2607
Echinococcus granulosus tissue type plasminogen activator 0.0172 0.202 0.202
Schistosoma mansoni microtubule-associated protein tau 0.076 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0215 0.2607 0.2607
Schistosoma mansoni biogenic amine (5HT) receptor 0.0215 0.2607 0.2607
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Onchocerca volvulus 0.0215 0.2607 0.4518
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0171 0.2011 0.3493
Schistosoma mansoni hypothetical protein 0.0063 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus neuropeptide Y receptor 0.0215 0.2607 0.2607
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0067 0.0116
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Trypanosoma cruzi p450 reductase, putative 0.0447 0.5758 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0095 0.0165
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0043 0.0075
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0447 0.5758 1
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Trypanosoma cruzi reductase, putative 0.0051 0.038 0.066
Echinococcus multilocularis neuropeptide Y receptor 0.0215 0.2607 0.2607
Echinococcus granulosus protein jagged 2 0.0027 0.0057 0.0057
Echinococcus multilocularis protein jagged 1 0.0027 0.0057 0.0057
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0447 0.5758 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0276 0.3437 0.3437
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0447 0.5758 0.5758
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0067 0.0116
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0215 0.2607 0.2607
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0051 0.038 0.1032
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0095 0.0095
Brugia malayi Melatonin receptor type 1A 0.0215 0.2607 0.4527
Echinococcus granulosus delta-like protein 1 0.0027 0.0057 0.0057
Mycobacterium tuberculosis Conserved protein 0.0031 0.0109 0.0346
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni notch 0.0027 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0051 0.038 0.066
Brugia malayi Importin beta-1 subunit 0.0031 0.0111 0.0193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0109 0.0109
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Onchocerca volvulus 0.0063 0.0551 0.0876
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0043 0.0075
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0029 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0095 0.0165
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0032 0.0055
Brugia malayi larval opioid receptor 0.0215 0.2607 0.4527
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0215 0.2607 0.4527
Schistosoma mansoni amine GPCR 0.0215 0.2607 0.2607
Brugia malayi neuropeptide F receptor 0.0215 0.2607 0.4527
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0133 0.0231
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Schistosoma mansoni myosin xvIII 0.0215 0.2607 0.2607
Echinococcus granulosus enteropeptidase 0.0063 0.0551 0.0551
Mycobacterium ulcerans monooxygenase 0.0051 0.038 0.0614
Schistosoma mansoni biogenic amine receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Leishmania major p450 reductase, putative 0.0447 0.5758 1
Echinococcus granulosus g protein coupled receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0171 0.2011 0.3493
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.019
Brugia malayi Serotonin receptor 0.0215 0.2607 0.4527
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0215 0.2607 0.4527
Brugia malayi putative neuropeptide receptor NPR1 0.0215 0.2607 0.4527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Echinococcus multilocularis snurportin 1 0.0331 0.4181 0.4181
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0071 0.0651 0.0651
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni notch 0.0027 0.0057 0.0057
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Echinococcus multilocularis orexin receptor type 2 0.0215 0.2607 0.2607
Entamoeba histolytica hypothetical protein 0.0025 0.0032 0.0157
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0095 0.0165
Brugia malayi EGF-like domain containing protein 0.0027 0.0057 0.0099
Onchocerca volvulus 0.0215 0.2607 0.4518
Brugia malayi sulfakinin receptor protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0109 0.019
Onchocerca volvulus 0.0215 0.2607 0.4518
Onchocerca volvulus 0.0063 0.0551 0.0876
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma cruzi hypothetical protein, conserved 0.0172 0.202 0.3508
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0071 0.0651 0.113
Loa Loa (eye worm) TK/ROR protein kinase 0.0172 0.202 0.3508
Toxoplasma gondii ABC1 family protein 0.0031 0.0109 0.0405
Echinococcus granulosus neuropeptide receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0109 0.019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0284 0.0494
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0215 0.2607 0.2607
Leishmania major heat shock protein 83-1 0.0033 0.0133 0.0231
Leishmania major NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0095 0.0165
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Echinococcus granulosus neuropeptide receptor 0.0215 0.2607 0.2607
Brugia malayi Kringle domain containing protein 0.0172 0.202 0.3508
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) diaphorase 0.0051 0.038 0.066
Brugia malayi Serotonin receptor 0.0215 0.2607 0.4527
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0551 0.0551
Echinococcus multilocularis allatostatin A receptor 0.0215 0.2607 0.2607
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Onchocerca volvulus 0.0051 0.038 0.0573
Plasmodium falciparum importin beta, putative 0.0031 0.0111 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.2607 0.2607
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0447 0.5758 1
Leishmania major cytochrome-b5 reductase, putative 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0109 0.0109
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0111 0.0193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni hypothetical protein 0.0215 0.2607 0.2607
Brugia malayi FAD binding domain containing protein 0.0276 0.3437 0.5969
Brugia malayi follicle stimulating hormone receptor 0.0215 0.2607 0.4527
Echinococcus granulosus biogenic amine 5HT receptor 0.0215 0.2607 0.2607
Mycobacterium ulcerans beta-lactamase 0.0031 0.0109 0.0141
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0051 0.038 0.066
Brugia malayi FAD binding domain containing protein 0.0447 0.5758 1
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Mycobacterium tuberculosis Probable lipase LipD 0.0031 0.0109 0.0346
Plasmodium vivax importin-beta 2, putative 0.0031 0.0111 0.0193
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0051 0.038 0.066
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0651 0.2409
Brugia malayi ORL1-like opioid receptor 0.0215 0.2607 0.4527
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0051 0.038 0.038
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0215 0.2607 0.4527
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0551 0.0551
Echinococcus multilocularis endoplasmin 0.0026 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) hypothetical protein 0.0443 0.57 0.99
Onchocerca volvulus 0.003 0.0095 0.0068
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0095 0.0095
Brugia malayi Cadherin domain containing protein 0.0027 0.0057 0.0099
Entamoeba histolytica type A flavoprotein, putative 0.0171 0.2011 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0099
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0215 0.2607 0.2607
Loa Loa (eye worm) hypothetical protein 0.0328 0.4147 0.7203
Echinococcus multilocularis neuropeptide Y receptor 0.0215 0.2607 0.2607
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0051 0.038 0.066
Loa Loa (eye worm) hypothetical protein 0.0215 0.2607 0.4527
Loa Loa (eye worm) neuropeptide F receptor 0.0215 0.2607 0.4527
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.014 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.2607 0.2607
Schistosoma mansoni endoplasmin 0.0033 0.0133 0.0133
Brugia malayi beta-lactamase 0.0031 0.0109 0.019
Brugia malayi hypothetical protein 0.0215 0.2607 0.4527
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0029 0.005
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0171 0.2011 0.3493
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0215 0.2607 0.2607
Trypanosoma brucei heat shock protein, putative 0.0033 0.0133 0.0231
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0133 0.0231
Echinococcus granulosus G protein coupled receptor 139 0.0215 0.2607 0.2607
Echinococcus multilocularis glycoprotein Antigen 5 0.0063 0.0551 0.0551
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0109 0.019
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0057 0.0057
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0215 0.2607 0.4527

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 6 % Percentage of growth inhibition of wild type Leishmania tropica lines at 15 microM. ChEMBL. 14736239
Inhibition (functional) = 6 % Percentage of growth inhibition of wild type Leishmania tropica Lines at 7 uM. ChEMBL. 14736239
Inhibition (functional) = 6 % Percentage of growth inhibition of wild type Leishmania tropica Lines at 3 uM. ChEMBL. 14736239
Inhibition (functional) = 6 % Percentage of growth inhibition of multidrug resistance Leishmania tropica Lines at 3 uM. ChEMBL. 14736239
Inhibition (functional) = 6 % Percent growth inhibition of wild type Leishmania tropica at 1 uM ChEMBL. 14736239
Inhibition (functional) = 6 % Percentage of growth inhibition of multidrug resistance Leishmania tropica Lines at 1 uM. ChEMBL. 14736239
Inhibition (functional) = 17.1 % Percentage of growth inhibition of multidrug resistance Leishmania tropica Lines at 7 uM. ChEMBL. 14736239
Inhibition (functional) = 50.6 % Percentage of growth inhibition of multidrug resistance Leishmania tropica Lines at 15 microM ChEMBL. 14736239

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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