Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0035 | 0.0091 | 0.2936 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Onchocerca volvulus | 0.0036 | 0.0099 | 0.0952 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.004 | 0.0134 | 0.0134 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0035 | 0.0091 | 0.021 |
Trichomonas vaginalis | proprotein convertase subtilisin/kexin type, putative | 0.0033 | 0.0073 | 0.0444 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0454 | 0.0454 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0191 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0142 | 0.1001 | 0.6061 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0061 | 0.0311 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0115 | 0.0768 | 0.0768 |
Toxoplasma gondii | subtilisin SUB12 | 0.0042 | 0.0154 | 0.0255 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0035 | 0.0091 | 0.021 |
Brugia malayi | Protein kinase domain containing protein | 0.0063 | 0.033 | 0.0977 |
Onchocerca volvulus | 0.0061 | 0.0311 | 0.3821 | |
Echinococcus multilocularis | cathepsin b | 0.0423 | 0.3376 | 0.7744 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.007 | 0.039 | 0.0895 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0062 | 0.0325 | 0.0745 |
Leishmania major | hypothetical protein, conserved | 0.0061 | 0.0311 | 0.2417 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Brugia malayi | Cathepsin L-like precursor | 0.0035 | 0.0091 | 0.0271 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0078 | 0.0454 | 0.1043 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.006 | 0.0305 | 0.0699 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0142 | 0.1001 | 0.2965 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0423 | 0.3376 | 0.3376 |
Schistosoma mansoni | furin-1 (S08 family) | 0.0074 | 0.0419 | 0.0419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.0106 | 0.0695 | 0.1595 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0035 | 0.0091 | 0.2936 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0042 | 0.0155 | 0.0375 |
Echinococcus granulosus | cathepsin b | 0.0423 | 0.3376 | 0.7744 |
Brugia malayi | glutaminase DH11.1 | 0.0219 | 0.1651 | 0.4892 |
Echinococcus multilocularis | Furin 1 | 0.004 | 0.0134 | 0.0308 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.006 | 0.0305 | 0.0305 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0035 | 0.0091 | 0.0091 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0078 | 0.0454 | 0.1043 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.0169 | 0.1227 | 0.3579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trichomonas vaginalis | glutaminase, putative | 0.0219 | 0.1651 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Toxoplasma gondii | kringle domain-containing protein | 0.0061 | 0.0311 | 0.0892 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Toxoplasma gondii | PAN domain-containing protein | 0.0326 | 0.2556 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Onchocerca volvulus | 0.0093 | 0.0583 | 0.7494 | |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.0454 | 0.1043 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0033 | 0.0072 | 0.0165 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.006 | 0.0305 | 0.0305 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus multilocularis | cysteine protease | 0.0035 | 0.0091 | 0.021 |
Echinococcus granulosus | tyrosine kinase | 0.007 | 0.039 | 0.0895 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0068 | 0.0372 | 0.0853 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0035 | 0.0091 | 0.2816 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0228 | 0.0593 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.0768 | 0.2207 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0057 | 0.0283 | 0.0758 |
Giardia lamblia | Cathepsin B precursor | 0.0142 | 0.1001 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0007 |
Brugia malayi | endoprotease bli-4 precursor | 0.0169 | 0.1227 | 0.3635 |
Mycobacterium ulcerans | glutaminase | 0.0219 | 0.1651 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0311 | 0.0843 |
Toxoplasma gondii | microneme protein MIC17C | 0.0035 | 0.0093 | 0.0007 |
Loa Loa (eye worm) | SRC-1 | 0.0078 | 0.0454 | 0.1271 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0029 | 0.0896 |
Schistosoma mansoni | glutaminase | 0.0219 | 0.1651 | 0.1651 |
Brugia malayi | Cathepsin L-like precursor | 0.0035 | 0.0091 | 0.0271 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.004 | 0.0134 | 0.0814 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0035 | 0.0091 | 0.0271 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0029 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0029 | 0.0086 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0057 | 0.0283 | 0.0283 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0078 | 0.0454 | 0.1043 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0091 | 0.0186 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0078 | 0.0454 | 0.1043 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0035 | 0.0091 | 0.021 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0033 | 0.0072 | 0.0165 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0033 | 0.0072 | 0.0214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0027 | 0.0029 | 0.0086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0142 | 0.1001 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0035 | 0.0091 | 0.2816 |
Entamoeba histolytica | cysteine protease, putative | 0.0035 | 0.0091 | 0.2816 |
Toxoplasma gondii | hypothetical protein | 0.0035 | 0.0093 | 0.0007 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Plasmodium vivax | vivapain-2 | 0.0035 | 0.0091 | 0.2936 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0035 | 0.0091 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.0768 | 0.2207 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0029 | 0.0086 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0276 | 0.2135 | 0.4897 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0061 | 0.0311 | 0.0922 |
Brugia malayi | calpain family protein 1 | 0.0057 | 0.0283 | 0.0838 |
Echinococcus multilocularis | 0.0136 | 0.095 | 0.218 | |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0073 | 0.0073 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0423 | 0.3376 | 0.3376 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Brugia malayi | Cathepsin L-like precursor | 0.0035 | 0.0091 | 0.0271 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.0103 | 0.0666 | 0.1528 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0103 | 0.0666 | 0.4032 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0155 | 0.0375 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0423 | 0.3376 | 0.3376 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Brugia malayi | celfurPC protein | 0.0136 | 0.095 | 0.2815 |
Loa Loa (eye worm) | ctsf protein | 0.0035 | 0.0091 | 0.0186 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0035 | 0.0091 | 0.0271 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.0029 | 0.0029 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.004 | 0.0134 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0099 | 0.021 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0191 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0078 | 0.0454 | 0.1043 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0539 | 0.4359 | 1 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1227 | 0.3579 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0033 | 0.0072 | 0.0165 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0033 | 0.0072 | 0.0072 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Loa Loa (eye worm) | hypothetical protein | 0.0423 | 0.3376 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.004 | 0.0134 | 0.0315 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0007 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0035 | 0.0091 | 0.0091 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0061 | 0.0311 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0035 | 0.0091 | 0.0844 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0068 | 0.0372 | 0.0853 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0103 | 0.0666 | 0.4032 |
Onchocerca volvulus | Cathepsin L homolog | 0.0035 | 0.0091 | 0.0844 |
Echinococcus granulosus | Furin 1 | 0.004 | 0.0134 | 0.0308 |
Giardia lamblia | Cathepsin B precursor | 0.0142 | 0.1001 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0042 | 0.0155 | 0.0355 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0007 |
Onchocerca volvulus | Cathepsin L homolog | 0.0035 | 0.0091 | 0.0844 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0027 | 0.0029 | 0.0086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.007 | 0.039 | 0.0895 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.0169 | 0.1227 | 0.1227 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0191 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.0454 | 0.1043 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0035 | 0.0091 | 0.0271 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0191 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0035 | 0.0091 | 0.021 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0142 | 0.1001 | 0.1001 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0142 | 0.1001 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Toxoplasma gondii | 1,3(4)-beta-glucanase | 0.0035 | 0.0093 | 0.0007 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0035 | 0.0091 | 0.021 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.004 | 0.0134 | 0.0814 |
Toxoplasma gondii | hypothetical protein | 0.0035 | 0.0093 | 0.0007 |
Echinococcus granulosus | cathepsin b | 0.0423 | 0.3376 | 0.7744 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.007 | 0.039 | 0.0895 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.004 | 0.0134 | 0.0814 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0078 | 0.0454 | 0.1043 |
Echinococcus granulosus | calpain A | 0.006 | 0.0305 | 0.0699 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0454 | 0.0454 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0078 | 0.0454 | 0.1043 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Brugia malayi | Cathepsin L-like precursor | 0.0035 | 0.0091 | 0.0271 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Loa Loa (eye worm) | cathepsin B | 0.0142 | 0.1001 | 0.2904 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0539 | 0.4359 | 1 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0276 | 0.2135 | 0.2135 |
Plasmodium vivax | vivapain-2 | 0.0035 | 0.0091 | 0.2936 |
Toxoplasma gondii | microneme protein MIC4 | 0.0035 | 0.0093 | 0.0007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0033 | 0.0072 | 0.0129 |
Brugia malayi | Cathepsin L-like precursor | 0.0035 | 0.0091 | 0.0271 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Toxoplasma gondii | MAPEG family protein | 0.0276 | 0.2135 | 0.8291 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.004 | 0.0134 | 0.0814 |
Toxoplasma gondii | microneme protein, putative | 0.0035 | 0.0093 | 0.0007 |
Onchocerca volvulus | 0.0115 | 0.0768 | 1 | |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Loa Loa (eye worm) | cysteine protease | 0.0035 | 0.0091 | 0.0186 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.0106 | 0.0695 | 0.1595 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0029 | 0.0176 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Loa Loa (eye worm) | TK protein kinase | 0.007 | 0.039 | 0.1079 |
Brugia malayi | calpain family protein 1 | 0.0057 | 0.0283 | 0.0838 |
Brugia malayi | proprotein convertase 2 | 0.0106 | 0.0695 | 0.206 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0007 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0078 | 0.0454 | 0.1043 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trichomonas vaginalis | hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Toxoplasma gondii | cathepsin B | 0.0142 | 0.1001 | 0.3691 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0035 | 0.0091 | 0.0186 |
Loa Loa (eye worm) | fibroinase | 0.0035 | 0.0091 | 0.0186 |
Giardia lamblia | Cathepsin B precursor | 0.0142 | 0.1001 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0078 | 0.0454 | 0.1043 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Brugia malayi | SRC-1 | 0.0078 | 0.0454 | 0.1346 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0035 | 0.0091 | 0.0186 |
Brugia malayi | cathepsin L-like precursor | 0.0027 | 0.0029 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0093 | 0.0191 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0093 | 0.0191 |
Echinococcus granulosus | cathepsin l1 | 0.0035 | 0.0091 | 0.021 |
Toxoplasma gondii | microneme protein MIC17A | 0.0035 | 0.0093 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0358 | 0.0982 |
Echinococcus granulosus | furin | 0.0169 | 0.1227 | 0.2815 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0035 | 0.0091 | 0.0271 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0311 | 0.0311 |
Loa Loa (eye worm) | glutaminase | 0.0219 | 0.1651 | 0.4848 |
Brugia malayi | protein-tyrosine kinase | 0.007 | 0.039 | 0.1156 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trichomonas vaginalis | leucine-rich repeat protein, BspA family | 0.0033 | 0.0073 | 0.0444 |
Onchocerca volvulus | 0.0035 | 0.0091 | 0.0844 | |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.0454 | 0.1043 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Trichomonas vaginalis | neuroendocrine convertase 2 precursor, putative | 0.0033 | 0.0073 | 0.0444 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0063 | 0.033 | 0.0898 |
Toxoplasma gondii | PAN/Apple domain-containing protein | 0.0035 | 0.0093 | 0.0007 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0033 | 0.0072 | 0.0072 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0423 | 0.3376 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0035 | 0.0091 | 0.021 |
Giardia lamblia | High cysteine membrane protein Group 2 | 0.0063 | 0.0328 | 0.2747 |
Toxoplasma gondii | microneme protein MIC17B | 0.0035 | 0.0093 | 0.0007 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0115 | 0.0768 | 0.0768 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0061 | 0.0311 | 0.0714 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0276 | 0.2135 | 0.4897 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0078 | 0.0454 | 0.1043 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0078 | 0.0454 | 0.1043 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0078 | 0.0454 | 0.1043 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.0103 | 0.0666 | 0.1528 |
Echinococcus multilocularis | calpain A | 0.006 | 0.0305 | 0.0699 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.007 | 0.039 | 0.0895 |
Brugia malayi | Kringle domain containing protein | 0.0061 | 0.0311 | 0.0922 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.007 | 0.039 | 0.0895 |
Echinococcus granulosus | cathepsin l1 | 0.0027 | 0.0029 | 0.0067 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0073 | 0.0444 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0061 | 0.0311 | 0.0714 |
Echinococcus multilocularis | cysteine protease | 0.0035 | 0.0091 | 0.021 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0035 | 0.0091 | 0.0271 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.006 | 0.0305 | 0.0699 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0078 | 0.0454 | 0.1043 |
Brugia malayi | Cathepsin L-like precursor | 0.0035 | 0.0091 | 0.0271 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Echinococcus multilocularis | cathepsin b | 0.0423 | 0.3376 | 0.7744 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0062 | 0.0325 | 0.0745 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.0106 | 0.0695 | 0.206 |
Onchocerca volvulus | 0.0035 | 0.0093 | 0.0866 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0423 | 0.3376 | 0.3376 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0093 | 0.0276 |
Toxoplasma gondii | PAN domain-containing protein | 0.0326 | 0.2556 | 1 |
Brugia malayi | Trypsin family protein | 0.0115 | 0.0768 | 0.2274 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0033 | 0.0072 | 0.0165 |
Entamoeba histolytica | protein kinase, putative | 0.0062 | 0.0325 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Loa Loa (eye worm) | TK protein kinase | 0.0062 | 0.0325 | 0.0883 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0078 | 0.0454 | 0.1043 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0033 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | glutaminase 2 | 0.0219 | 0.1651 | 0.4848 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0423 | 0.3376 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0035 | 0.0091 | 0.0913 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0035 | 0.0091 | 0.2936 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0035 | 0.0091 | 0.0553 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0283 | 0.0758 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.004 | 0.0134 | 0.0814 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.006 mg l-1 | Tested in vitro for minimum inhibitory concentration against trichophyton mentagrophytes | ChEMBL. | 8126700 |
MIC (functional) | = 0.01 mg l-1 | Tested in vitro for minimum inhibitory concentration against microsporum canis | ChEMBL. | 8126700 |
MIC (functional) | = 0.1 mg l-1 | Tested in vitro for minimum inhibitory concentration against Aspergillus fumigatus | ChEMBL. | 8126700 |
MIC (functional) | = 1.56 mg l-1 | Tested in vitro for minimum inhibitory concentration against candida parapsilosis 39 | ChEMBL. | 8126700 |
MIC (functional) | = 3.13 mg l-1 | Tested in vitro for minimum inhibitory concentration against sporothrix schenck ii | ChEMBL. | 8126700 |
MIC (functional) | = 50 mg l-1 | Tested in vitro for minimum inhibitory concentration against candida albicans 124 | ChEMBL. | 8126700 |
MIC (functional) | = 50 mg l-1 | Tested in vitro for minimum inhibitory concentration against candida albicans 9 | ChEMBL. | 8126700 |
MIC (functional) | = 50 mg l-1 | Tested in vitro for minimum inhibitory concentration against candida albicans 124 | ChEMBL. | 8126700 |
MIC (functional) | = 50 mg l-1 | Tested in vitro for minimum inhibitory concentration against candida albicans 9 | ChEMBL. | 8126700 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.