Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0496 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0496 | 0.0496 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0237 | 0.7362 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.019 | 0.5736 | 0.5736 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.5736 | 0.5736 |
Brugia malayi | RNA recognition motif domain containing protein | 0.019 | 0.5736 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0528 | 0.0106 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0635 | 0.3707 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0528 | 0.0528 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0915 | 0.2653 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.4899 | 0.4899 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0496 | 0.9575 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0915 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0845 | 0.0845 |
Echinococcus granulosus | lamin | 0.0055 | 0.1119 | 0.1119 |
Echinococcus granulosus | tar DNA binding protein | 0.019 | 0.5736 | 0.5736 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0266 | 0.5033 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0518 | 0.0518 |
Schistosoma mansoni | jumonji domain containing protein | 0.006 | 0.1312 | 0.1312 |
Onchocerca volvulus | 0.0037 | 0.0528 | 0.2429 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.0915 | 0.0701 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1119 | 0.1119 |
Onchocerca volvulus | 0.0055 | 0.1119 | 1 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0528 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0528 | 0.308 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1085 | 0.1085 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0915 | 0.1417 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.074 | 0.4316 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.4899 | 0.4899 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0635 | 0.3804 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.2131 | 0.2456 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0266 | 0.0266 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0528 | 0.0106 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0528 | 0.0143 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.006 | 0.1312 | 0.1312 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0845 | 0.0845 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0123 | 0.3449 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0915 | 0.2012 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0528 | 0.0143 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0266 | 0.5123 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0528 | 0.092 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0266 | 0.5033 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.1042 | 0.1817 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0157 | 0.0157 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0123 | 0.3449 | 0.4356 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.3449 | 0.3449 |
Onchocerca volvulus | 0.0037 | 0.0528 | 0.2429 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0266 | 0.0266 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0518 | 0.0904 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0528 | 0.0528 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.044 |
Schistosoma mansoni | lamin | 0.0055 | 0.1119 | 0.1119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0234 | 0.1363 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.1714 | 0.1714 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0528 | 0.0143 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0084 | 0.2131 | 0.8334 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.1312 | 0.2287 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.074 | 0.4316 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.1714 | 0.1714 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.2131 | 0.2456 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.5736 | 0.5736 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0915 | 0.0915 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0094 | 0.2452 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.1312 | 0.1312 |
Brugia malayi | TAR-binding protein | 0.019 | 0.5736 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0528 | 0.0528 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0315 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.3449 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.0915 | 0.1417 |
Loa Loa (eye worm) | RNA binding protein | 0.019 | 0.5736 | 0.5736 |
Brugia malayi | RNA binding protein | 0.019 | 0.5736 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0845 | 0.0845 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0635 | 0.1107 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0635 | 0.3707 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.1428 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.1119 | 0.1119 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.5736 | 0.5736 |
Onchocerca volvulus | 0.0037 | 0.0528 | 0.2429 | |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0123 | 0.3449 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.2131 | 0.2456 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.1119 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0496 | 0.0496 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0535 | 0.0535 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.0518 | 0.9825 |
Echinococcus multilocularis | musashi | 0.0055 | 0.1119 | 0.1119 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.1714 | 0.1714 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.1042 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0528 | 0.0528 |
Echinococcus multilocularis | lamin | 0.0055 | 0.1119 | 0.1119 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0123 | 0.3449 | 0.3449 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.1119 | 0.1951 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0528 | 0.0528 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.006 | 0.1312 | 0.1312 |
Echinococcus granulosus | geminin | 0.0165 | 0.4899 | 0.4899 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0845 | 0.0845 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.0518 | 0.1503 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0496 | 0.9407 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0256 | 0.0256 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.1714 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0266 | 0.0463 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0157 | 0.0157 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.0518 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.5736 | 0.5736 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.1119 | 0.1119 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0518 | 0.0518 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.0518 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.2131 | 0.2456 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0518 | 0.9825 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.0915 | 0.1417 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0528 | 0.0528 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0528 | 0.308 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.006 | 0.1312 | 0.1312 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0518 | 0.9825 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0123 | 0.0123 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0845 | 0.0845 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.019 | 0.5736 | 0.5736 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0528 | 0.0528 |
Brugia malayi | RNA, U transporter 1 | 0.0084 | 0.2121 | 0.3697 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0266 | 0.0266 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0528 | 0.308 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0518 | 0.0129 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.0496 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0528 | 0.0528 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0256 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0496 | 0.0496 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.1714 | 0.1714 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.044 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.006 | 0.1312 | 0.1312 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0528 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.0915 | 0.1417 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0915 | 0.0915 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0266 | 0.5033 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0528 | 0.092 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0528 | 0.153 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0915 | 0.2653 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0094 | 0.2452 | 0.2918 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0518 | 0.0904 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0845 | 0.0845 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.0915 | 0.1417 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0528 | 0.0106 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.1714 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.2131 | 0.2456 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0528 | 0.0143 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.1042 | 0.1817 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0496 | 0.0496 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0528 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.1119 | 0.1119 |
Echinococcus multilocularis | snurportin 1 | 0.0315 | 1 | 1 |
Onchocerca volvulus | 0.0055 | 0.1119 | 1 | |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0528 | 0.092 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.0518 | 0.9825 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.5736 | 0.5736 |
Schistosoma mansoni | lamin | 0.0055 | 0.1119 | 0.1119 |
Echinococcus multilocularis | geminin | 0.0165 | 0.4899 | 0.4899 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0845 | 0.0845 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0915 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0845 | 0.0845 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.0218 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.0915 | 0.1417 |
Onchocerca volvulus | 0.0049 | 0.0915 | 0.7386 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0915 | 0.0915 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0535 | 0.0535 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0915 | 0.1595 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0915 | 0.2653 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0518 | 0.1503 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0157 | 0.0157 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0528 | 0.0143 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0915 | 0.1417 |
Schistosoma mansoni | hypothetical protein | 0.0315 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0528 | 0.0528 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.1312 | 0.2287 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0266 | 0.077 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0072 | 0.1714 | 0.1714 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0528 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.0915 | 0.0701 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0528 | 0.308 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0528 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0528 | 0.092 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0266 | 0.0266 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0915 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1042 | 0.1042 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.1119 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0528 | 0.0528 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.2131 | 0.2456 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0915 | 0.1595 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.1714 | 0.1714 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0915 | 0.2012 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.3449 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0528 | 0.0106 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.1119 | 0.1951 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.1119 | 0.1119 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0528 | 0.308 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0075 | 0.0824 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0845 | 0.1473 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0528 | 0.153 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0528 | 0.0528 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0915 | 0.1417 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0496 | 0.0097 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0528 | 0.0106 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0528 | 0.0528 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0478 | 0.0478 |
Loa Loa (eye worm) | TAR-binding protein | 0.019 | 0.5736 | 0.5736 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0234 | 0.1363 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.3449 | 0.3449 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0049 | 0.0915 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0478 | 0.0478 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.074 | 0.5142 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.1312 | 0.1312 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0094 | 0.2452 | 0.2918 |
Brugia malayi | Heterochromatin protein 1 | 0.0072 | 0.1714 | 0.2988 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0528 | 0.0143 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0123 | 0.3449 | 0.3449 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0528 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0123 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0635 | 0.0635 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0075 | 0.044 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.3449 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0528 | 0.0143 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0094 | 0.2452 | 0.2918 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0478 | 0.0833 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0528 | 0.0143 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0528 | 0.308 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.1714 | 0.1714 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 12.37 % | Myocardial infarction (MI) size was calculated as a percentage of the infarct area to the total area of the left ventricle of male chinchilla rabbits | ChEMBL. | 9871565 |
LD50 (ADMET) | = 1210 mg kg-1 | Lethal dose to produce acute toxicity was evaluated in white crossbred mice weighing 20-25 g | ChEMBL. | 9871565 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.