Detailed information for compound 268116

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 292.32 | Formula: C10H12N8OS
  • H donors: 2 H acceptors: 4 LogP: 0.87 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1C[C@H]([C@@H](S1)n1cnc2c1ncnc2N)N=[N+]=[N-]
  • InChi: 1S/C10H12N8OS/c11-8-7-9(14-3-13-8)18(4-15-7)10-6(16-17-12)1-5(2-19)20-10/h3-6,10,19H,1-2H2,(H2,11,13,14)/t5-,6+,10+/m0/s1
  • InChiKey: YLXJDLTWWNTGDI-BAJZRUMYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0119 0.0384 0.054
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0115 0.0368 0.0583
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0225 0.1244
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0088 0.0123
Onchocerca volvulus 0.0052 0.0132 0.0143
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0073 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0134 0.044 0.0618
Toxoplasma gondii calcium binding egf domain-containing protein 0.0065 0.0181 0.0486
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0016 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0119 0.0384 0.054
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0119 0.0383 0.1889
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0204 0.2519
Echinococcus granulosus slit 2 protein 0.0025 0.0031 0.0031
Schistosoma mansoni neuropeptide receptor 0.0119 0.0384 0.0384
Mycobacterium ulcerans beta-lactamase 0.0077 0.0225 0.2794
Schistosoma mansoni jumonji domain containing protein 0.0119 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0077 0.0225 0.0316
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0228 0.0792 0.0792
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus granulosus neural cadherin 0.0025 0.0031 0.0031
Echinococcus granulosus lamin 0.0024 0.0029 0.0029
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.1116 0.4115 0.4115
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.0843 0.1184
Loa Loa (eye worm) phosphatidylinositol kinase 0.0052 0.0132 0.0186
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0016 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.016 0.1937
Echinococcus granulosus lysine specific demethylase 5A 0.0447 0.1612 0.1612
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0052 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0115 0.0368 0.0517
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0065 0.0181 0.0254
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni ferritin 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Loa Loa (eye worm) phosphatidylinositol 3 0.1593 0.5901 0.829
Plasmodium vivax SET domain protein, putative 0.0276 0.097 0.8394
Echinococcus granulosus protein jagged 2 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Leishmania major phosphatidylinositol kinase related protein, putative 0.0052 0.0132 0.091
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0225 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0225 0.1244
Leishmania major hypothetical protein, conserved 0.0115 0.0368 0.2701
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0115 0.0368 0.0368
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0204 0.0315
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0119 0.0384 0.0455
Echinococcus multilocularis integrin beta 2 0.0584 0.2125 0.2125
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0052 0.0132 0.0132
Schistosoma mansoni opsin-like receptor 0.0119 0.0384 0.0384
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0052 0.0132 0.0197
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0073 0.021 0.1499
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0132 0.0132
Schistosoma mansoni amine GPCR 0.0119 0.0384 0.0384
Echinococcus multilocularis dnaJ subfamily B 0.0368 0.1317 0.1317
Loa Loa (eye worm) hypothetical protein 0.0065 0.0181 0.0254
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0368 0.0583
Echinococcus granulosus neurogenic locus protein delta 0.0025 0.0031 0.0031
Echinococcus granulosus integrin alpha 3 0.005 0.0126 0.0126
Echinococcus multilocularis neuropeptides capa receptor 0.0119 0.0384 0.0384
Entamoeba histolytica hypothetical protein 0.0032 0.006 0.0077
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1161 0.4284 0.5279
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0193 0.0659 0.0926
Echinococcus multilocularis neuropeptide Y receptor 0.0119 0.0384 0.0384
Schistosoma mansoni hypothetical protein 0.0048 0.0118 0.0118
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0073 0.021 0.0324
Plasmodium vivax importin-beta 2, putative 0.0026 0.0036 0.0199
Loa Loa (eye worm) hypothetical protein 0.005 0.0126 0.0177
Giardia lamblia TCP-1 chaperonin subunit beta 0.0023 0.0026 0.0038
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Schistosoma mansoni cpg binding protein 0.0027 0.0041 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0204 0.1456
Giardia lamblia hypothetical protein 0.0025 0.0034 0.006
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0544 0.1974 0.2428
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0118 0.0118
Echinococcus granulosus fmrfamide receptor 0.0119 0.0384 0.0384
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0052 0.0132 0.0197
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0006 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0225 0.0225
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0115 0.0368 0.0368
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0057 0.0073
Onchocerca volvulus 0.0119 0.0384 0.0455
Echinococcus multilocularis microtubule associated protein 2 0.2688 1 1
Trypanosoma brucei unspecified product 0.0028 0.0041 0.0145
Trichomonas vaginalis spcc417.12 protein, putative 0.0223 0.0772 0.0946
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0073 0.021 0.0251
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0132 0.0132
Onchocerca volvulus 0.0119 0.0384 0.0455
Loa Loa (eye worm) integrin alpha pat-2 0.0105 0.033 0.0464
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0359 0.1281 0.1799
Echinococcus granulosus ferritin 0.0025 0.0031 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0383 0.0539
Echinococcus granulosus integrin beta 2 0.0584 0.2125 0.2125
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0052 0.0132 0.0346
Giardia lamblia GTOR 0.0052 0.0132 0.0346
Onchocerca volvulus 0.0119 0.0384 0.0455
Schistosoma mansoni hypothetical protein 0.0119 0.0384 0.0384
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0225 0.027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Echinococcus multilocularis fibrillin 2 0.0025 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0368 0.0583
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0218 0.0307
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0193 0.0659 0.0659
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0088 0.0466
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Onchocerca volvulus 0.0025 0.0031 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0368 0.0446
Trichomonas vaginalis hypothetical protein 0.0025 0.0034 0.0034
Brugia malayi Dopamine receptor 0.0119 0.0384 0.054
Schistosoma mansoni gliotactin 0.0223 0.0772 0.0772
Brugia malayi Serotonin receptor 0.0119 0.0384 0.054
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0118 0.0166
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0115 0.0368 0.0368
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0137 0.1089
Trypanosoma brucei Aminopeptidase M1, putative 0.0073 0.021 0.1005
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0073 0.021 0.1728
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0115 0.0368 0.0517
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0204 0.1456
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0368 0.0583
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1645 0.6096 1
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0073 0.021 0.1499
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0119 0.0384 0.054
Mycobacterium ulcerans bacterioferritin BfrA 0.0025 0.0031 0.0241
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0544 0.1974 0.3224
Onchocerca volvulus 0.0119 0.0384 0.0455
Brugia malayi AKH receptor 0.0119 0.0384 0.054
Echinococcus multilocularis lamin dm0 0.0024 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Plasmodium vivax hypothetical protein, conserved 0.0325 0.1153 1
Echinococcus granulosus dna polymerase kappa 0.004 0.0088 0.0088
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0228 0.0792 0.1282
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0052 0.0132 0.061
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.016 0.1119
Onchocerca volvulus 0.0223 0.0772 0.0934
Plasmodium vivax phosphodiesterase gamma, putative 0.0115 0.0368 0.3113
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0223 0.0772 0.0772
Schistosoma mansoni ap endonuclease 0.002 0.0013 0.0013
Schistosoma mansoni jumonji/arid domain-containing protein 0.0447 0.1612 0.1612
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Schistosoma mansoni hypothetical protein 0.0502 0.1816 0.1816
Mycobacterium ulcerans lipase LipD 0.0077 0.0225 0.2794
Brugia malayi jmjC domain containing protein 0.0119 0.0383 0.0539
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0013 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.016 0.1937
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0013 0.0018
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0119 0.0384 0.054
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0132 0.061
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0023 0.0026 0.0026
Schistosoma mansoni integrin beta subunit 0.0465 0.1677 0.1677
Leishmania major phosphatidylinositol 3-kinase, putative 0.0228 0.0792 0.5932
Onchocerca volvulus 0.0073 0.021 0.0239
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0073 0.021 0.0251
Leishmania major phosphatidylinositol 3-kinase, putative 0.0052 0.0132 0.091
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1645 0.6096 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0225 0.027
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0228 0.0792 0.5932
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0544 0.1974 0.2773
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0088 0.0088
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0119 0.0384 0.0384
Brugia malayi SET domain containing protein 0.0023 0.0024 0.0034
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0228 0.0792 0.6846
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0943 0.3466 0.3466
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1918 0.7118 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0544 0.1974 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0223 0.0772 0.0772
Giardia lamblia Tenascin-like 0.0025 0.0034 0.006
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0031 0.0031
Schistosoma mansoni neuroligin 3 (S09 family) 0.0223 0.0772 0.0772
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0225 0.027
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1645 0.6096 0.7515
Loa Loa (eye worm) hypothetical protein 0.0052 0.0132 0.0186
Echinococcus multilocularis Zinc finger, PHD finger 0.0228 0.0792 0.0792
Brugia malayi Melatonin receptor type 1A 0.0119 0.0384 0.054
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0053
Echinococcus granulosus notch 0.0025 0.0031 0.0031
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0119 0.0384 0.0384
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0228 0.0792 0.1282
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0119 0.0384 0.0384
Schistosoma mansoni septate junction protein 0.0025 0.0031 0.0031
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0228 0.0792 0.0792
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0016 0.0061
Onchocerca volvulus 0.0223 0.0772 0.0934
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.0184 0.0258
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0828 0.3037 0.3037
Schistosoma mansoni survival motor neuron protein 0.01 0.0312 0.0312
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0325 0.1153 0.1153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Entamoeba histolytica hypothetical protein 0.0052 0.0132 0.0197
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus granulosus neuropeptides capa receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0571 0.2074 0.2913
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0031 0.0031
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus multilocularis peregrin 0.0325 0.1153 0.1153
Schistosoma mansoni notch 0.0025 0.0031 0.0031
Echinococcus multilocularis neuropeptide receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1319 0.4874 0.4874
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0228 0.0792 0.0792
Brugia malayi hypothetical protein 0.0032 0.006 0.0084
Loa Loa (eye worm) hypothetical protein 0.1319 0.4874 0.6847
Echinococcus multilocularis serotonin receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Schistosoma mansoni hypothetical protein 0.0048 0.0118 0.0118
Leishmania major cAMP-specific phosphodiesterase, putative 0.0115 0.0368 0.2701
Loa Loa (eye worm) hypothetical protein 0.0115 0.0368 0.0517
Brugia malayi jmjC domain containing protein 0.0119 0.0383 0.0539
Brugia malayi beta-lactamase family protein 0.0077 0.0225 0.0316
Schistosoma mansoni hypothetical protein 0.0277 0.0976 0.0976
Toxoplasma gondii ABC1 family protein 0.0077 0.0225 0.0614
Schistosoma mansoni alpha-1 adrenergic receptor 0.0119 0.0384 0.0384
Schistosoma mansoni neuropeptide F-like receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.012 0.0389 0.0389
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0052 0.0132 0.0346
Echinococcus multilocularis chromobox protein 1 0.0075 0.0218 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Loa Loa (eye worm) hypothetical protein 0.0119 0.0383 0.0539
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0368 0.0583
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0397 0.0397
Schistosoma mansoni microtubule-associated protein tau 0.2688 1 1
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0119 0.0383 0.1073
Brugia malayi follicle stimulating hormone receptor 0.0359 0.1281 0.1799
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) hypothetical protein 0.0442 0.1592 0.2236
Schistosoma mansoni amine GPCR 0.0119 0.0384 0.0384
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0204 0.2519
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0165 0.0165
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0288 0.1016 0.1016
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0052 0.0132 0.0132
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1645 0.6096 0.7515
Loa Loa (eye worm) neuropeptide F receptor 0.0119 0.0384 0.054
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0023 0.0026 0.0026
Echinococcus granulosus serotonin receptor 0.0119 0.0384 0.0384
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0052 0.0132 0.0132
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0016 0.0006
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0016 0.0006
Entamoeba histolytica hypothetical protein 0.0032 0.006 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0041 0.0047
Schistosoma mansoni cell polarity protein 0.0025 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Brugia malayi G protein-coupled receptor F59B2.13 0.0119 0.0384 0.054
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0006 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0943 0.3466 1
Leishmania major T-complex protein 1, beta subunit, putative 0.0023 0.0026 0.0099
Brugia malayi EGF-like domain containing protein 0.0025 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0016 0.0061
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0016 0.0061
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0016 0.0016
Echinococcus multilocularis expressed protein 0.0025 0.0031 0.0031
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0115 0.0368 0.0517
Onchocerca volvulus Arrow homolog 0.0065 0.0181 0.0203
Leishmania major DNA polymerase eta, putative 0.0066 0.0184 0.1302
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Onchocerca volvulus Neuropeptide F receptor homolog 0.0119 0.0384 0.0455
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0029 0.0041
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0115 0.0368 0.0583
Brugia malayi Carboxylesterase family protein 0.0223 0.0772 0.1085
Echinococcus multilocularis para nitrobenzyl esterase 0.0223 0.0772 0.0772
Schistosoma mansoni notch 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0073 0.021 0.0295
Echinococcus granulosus neuropeptide receptor 0.0119 0.0384 0.0384
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Echinococcus multilocularis integrin alpha ps 0.0105 0.033 0.033
Echinococcus multilocularis integrin alpha ps 0.0105 0.033 0.033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis fmrfamide receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0052 0.0132 0.0132
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0052 0.0132 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0041 0.0145
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0016 0.0018
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0368 0.1314 0.3768
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0088 0.0101
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0088 0.0986
Schistosoma mansoni fkbp-rapamycin associated protein 0.0052 0.0132 0.0132
Entamoeba histolytica protein kinase rad3, putative 0.0052 0.0132 0.0197
Schistosoma mansoni biogenic amine receptor 0.0119 0.0384 0.0384
Mycobacterium ulcerans bacterioferritin BfrB 0.0025 0.0031 0.0241
Echinococcus multilocularis dna polymerase kappa 0.004 0.0088 0.0088
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0088 0.0088
Echinococcus granulosus lamin dm0 0.0024 0.0029 0.0029
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0132 0.0186
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0119 0.0384 0.0384
Schistosoma mansoni neuropeptide receptor 0.0119 0.0384 0.0384
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Brugia malayi ORL1-like opioid receptor 0.0119 0.0384 0.054
Onchocerca volvulus 0.0119 0.0384 0.0455
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1028 0.3786 0.5319
Echinococcus granulosus aminopeptidase N 0.0073 0.021 0.021
Brugia malayi Integrin beta pat-3 precursor 0.0677 0.2473 0.3475
Schistosoma mansoni intermediate filament proteins 0.0024 0.0029 0.0029
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0137 0.1634
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0204 0.2519
Brugia malayi G-protein coupled receptor 0.0119 0.0384 0.054
Echinococcus multilocularis neuropeptide s receptor 0.0533 0.1935 0.1935
Onchocerca volvulus 0.0077 0.0225 0.0258
Brugia malayi hypothetical protein 0.0134 0.044 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0368 0.0446
Loa Loa (eye worm) oxidoreductase 0.0021 0.0016 0.0023
Echinococcus multilocularis geminin 0.0502 0.1816 0.1816
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0119 0.0384 0.0384
Trypanosoma cruzi Aminopeptidase M1, putative 0.0073 0.021 0.0324
Mycobacterium tuberculosis Carboxylesterase LipT 0.0223 0.0772 0.4346
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0013 0.0018
Loa Loa (eye worm) melatonin receptor type 1A 0.0119 0.0384 0.054
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0016 0.0027
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0165 0.0904
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0088 0.0123
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0052 0.0132 0.0132
Brugia malayi Importin beta-1 subunit 0.0026 0.0036 0.005
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0276 0.097 0.097
Echinococcus granulosus cpg binding protein 0.0027 0.0041 0.0041
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0544 0.1974 0.3224
Echinococcus granulosus biogenic amine 5HT receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0115 0.0368 0.0368
Echinococcus multilocularis cpg binding protein 0.0027 0.0041 0.0041
Mycobacterium leprae conserved hypothetical protein 0.0052 0.0132 0.5563
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0029 0.0041
Schistosoma mansoni protein phosphatase 2C 0.0119 0.0383 0.0383
Brugia malayi Tachykinin-like peptides receptor 99D 0.0119 0.0384 0.054
Brugia malayi putative neuropeptide receptor 0.0119 0.0384 0.054
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0228 0.0792 0.6837
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0041
Loa Loa (eye worm) carboxylesterase 0.1319 0.4874 0.6847
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0115 0.0368 0.0368
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0204 0.8998
Schistosoma mansoni notch 0.0025 0.0031 0.0031
Schistosoma mansoni BC026374 protein (S09 family) 0.0223 0.0772 0.0772
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0132 0.091
Schistosoma mansoni acetylcholinesterase 0.0223 0.0772 0.0772
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) jmjC domain-containing protein 0.0447 0.1612 0.2265
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0126 0.0683
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0115 0.0368 0.0583
Loa Loa (eye worm) hypothetical protein 0.0943 0.3466 0.4869
Echinococcus granulosus g-protein coupled receptor 0.0119 0.0384 0.0384
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0016 0.0061
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0095 0.0097
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0115 0.0368 0.0583
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0036 0.0116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Echinococcus granulosus expressed protein 0.0025 0.0031 0.0031
Onchocerca volvulus Putative cubilin 0.0025 0.0031 0.0018
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0225 0.1244
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0119 0.0383 0.0383
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0225 0.1244
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0225 0.1861
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0025 0.0031 0.0145
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0228 0.0792 0.3975
Echinococcus granulosus para nitrobenzyl esterase 0.0223 0.0772 0.0772
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0165 0.2004
Schistosoma mansoni hypothetical protein 0.0325 0.1153 0.1153
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.005
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0107 0.0125
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0016 0.0027
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0031 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0165 0.0232
Schistosoma mansoni hypothetical protein 0.0032 0.006 0.006
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0052 0.0132 0.0132
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0828 0.3037 0.4266
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) hypothetical protein 0.0065 0.0181 0.0254
Echinococcus granulosus sex peptide receptor 0.0119 0.0384 0.0384
Echinococcus granulosus phd:f box containing protein 0.0119 0.0383 0.0383
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.0507 0.0713
Schistosoma mansoni biogenic amine receptor 0.0119 0.0384 0.0384
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Trichomonas vaginalis chaperonin, putative 0.0023 0.0026 0.0024
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus multilocularis ferritin 0.0025 0.0031 0.0031
Schistosoma mansoni cpg binding protein 0.0026 0.0035 0.0035
Onchocerca volvulus Alhambra homolog 0.0325 0.1153 0.1404
Brugia malayi beta-lactamase 0.0077 0.0225 0.0316
Loa Loa (eye worm) hypothetical protein 0.0052 0.0132 0.0186
Schistosoma mansoni integrin alpha-4 0.0448 0.1613 0.1613
Schistosoma mansoni hypothetical protein 0.0119 0.0384 0.0384
Entamoeba histolytica hypothetical protein 0.0052 0.0132 0.0197
Echinococcus granulosus dna polymerase eta 0.0066 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0023
Schistosoma mansoni neuropeptide receptor 0.0119 0.0384 0.0384
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0016 0.001
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0371 0.1327 0.216
Loa Loa (eye worm) hypothetical protein 0.0053 0.0137 0.0192
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0982 0.3613 0.5076
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0204 0.0315
Brugia malayi PHD-finger family protein 0.0325 0.1153 0.162
Loa Loa (eye worm) hypothetical protein 0.0073 0.021 0.0295
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0023 0.0026 0.0067
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.0843 0.1184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0115 0.0368 0.0368
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0225 0.0316
Mycobacterium tuberculosis Conserved protein 0.0077 0.0225 0.1244
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0119 0.0384 0.0384
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0204 0.8998
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0115 0.0368 0.181
Toxoplasma gondii calcium binding egf domain-containing protein 0.0065 0.0181 0.0486
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0041 0.0249
Leishmania major hypothetical protein, conserved 0.0027 0.0041 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0368 0.0583
Schistosoma mansoni integrin alpha 0.0105 0.033 0.033
Echinococcus multilocularis snurportin 1 0.0277 0.0976 0.0976
Toxoplasma gondii hypothetical protein 0.0025 0.0034 0.006
Schistosoma mansoni notch 0.0025 0.0031 0.0031
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0026 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0218 0.0262
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0088 0.0123
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0088 0.0123
Echinococcus granulosus fibrillin 2 0.0025 0.0034 0.0034
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0041 0.0278
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0052 0.0132 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0118 0.0118
Loa Loa (eye worm) PDE1B protein 0.0115 0.0368 0.0517
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1645 0.6096 1
Echinococcus multilocularis importin subunit beta 1 0.0026 0.0036 0.0036
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0383 0.0539
Brugia malayi Serotonin receptor 0.0119 0.0384 0.054
Giardia lamblia Neurogenic locus notch-like protein 0.0025 0.0034 0.006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0182 0.0182
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0115 0.0368 0.0517
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0119 0.0384 0.0384
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1161 0.4284 0.5279
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0088 0.0382
Entamoeba histolytica hypothetical protein 0.1329 0.4914 0.8057
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0119 0.0384 0.0384
Echinococcus granulosus dro:myosuppressin receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis BC026374 protein (S09 family) 0.0223 0.0772 0.0772
Brugia malayi sulfakinin receptor protein 0.0119 0.0384 0.054
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0265 0.093 0.093
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0119 0.0384 0.054
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0073 0.021 0.0324
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Onchocerca volvulus 0.0119 0.0384 0.0455
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0276 0.097 0.097
Schistosoma mansoni biogenic amine (5HT) receptor 0.0119 0.0384 0.0384
Echinococcus granulosus survival motor neuron protein 1 0.0489 0.177 0.177
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0119 0.0384 0.0384
Brugia malayi Pre-SET motif family protein 0.0276 0.097 0.1363
Schistosoma mansoni aminopeptidase A (M01 family) 0.0073 0.021 0.021
Onchocerca volvulus 0.0025 0.0031 0.0018
Brugia malayi RNA, U transporter 1 0.0074 0.0215 0.0302
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0193 0.0659 0.0659
Onchocerca volvulus 0.0052 0.0132 0.0143
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0057 0.0336
Loa Loa (eye worm) hypothetical protein 0.012 0.0387 0.0544
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus jumonji domain containing protein 0.0452 0.1629 0.1629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0126 0.0683
Brugia malayi RE15519p 0.0119 0.0384 0.054
Loa Loa (eye worm) hypothetical protein 0.0065 0.0181 0.0254
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0106 0.0335 0.1645
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0136 0.019
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Trichomonas vaginalis ferritin, putative 0.0025 0.0031 0.0031
Schistosoma mansoni jumonji domain containing protein 0.0897 0.3297 0.3297
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0052 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Mycobacterium ulcerans aminopeptidase N PepN 0.0073 0.021 0.2594
Echinococcus multilocularis dro:myosuppressin receptor 0.0119 0.0384 0.0384
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0115 0.0368 0.3133
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0119 0.0384 0.0384
Schistosoma mansoni ferritin 0.0025 0.0031 0.0031
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0073 0.021 0.0251
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0115 0.0368 0.0517
Brugia malayi Peptidase family M1 containing protein 0.0073 0.021 0.0295
Echinococcus granulosus jumonji domain containing 1A 0.0119 0.0383 0.0383
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0016 0.0047
Echinococcus granulosus g protein coupled receptor 0.0119 0.0384 0.0384
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0115 0.0368 0.0368
Leishmania major hypothetical protein, conserved 0.0119 0.0383 0.2819
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0016 0.0023
Echinococcus multilocularis serine protein kinase ATM 0.0052 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.3133
Trypanosoma cruzi target of rapamycin kinase 3 0.0052 0.0132 0.0197
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0016 0.0061
Echinococcus multilocularis adam 0.0025 0.0034 0.0034
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0225 0.1244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0016 0.0047
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0223 0.0772 0.0772
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Echinococcus granulosus neuropeptide Y receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0225 0.027
Trichomonas vaginalis rotamase, putative 0.0032 0.0057 0.0063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0193 0.0659 0.0659
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0052 0.0132 0.1076
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0073 0.021 0.1499
Brugia malayi Heterochromatin protein 1 0.0075 0.0218 0.0307
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.1049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0126 0.0683
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0659 0.0659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Schistosoma mansoni myosin xvIII 0.0119 0.0384 0.0384
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0016 0.001
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0088 0.0123
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0052 0.0132 0.1076
Echinococcus granulosus PHD finger protein rhinoceros 0.0325 0.1153 0.1153
Brugia malayi hypothetical protein 0.0628 0.2288 0.3214
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0228 0.0792 0.097
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Brugia malayi larval opioid receptor 0.0119 0.0384 0.054
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0019 0.0016
Onchocerca volvulus 0.0442 0.1592 0.1946
Brugia malayi EGF-like domain containing protein 0.0025 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0134 0.044 0.0618
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0013 0.0041
Toxoplasma gondii PHD-finger domain-containing protein 0.0325 0.1153 0.3302
Loa Loa (eye worm) acetylcholinesterase 1 0.1319 0.4874 0.6847
Echinococcus granulosus peregrin 0.0325 0.1153 0.1153
Schistosoma mansoni ferritin 0.0025 0.0031 0.0031
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Schistosoma mansoni phd/f-box containing protein 0.0119 0.0383 0.0383
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus chromobox protein 1 0.0075 0.0218 0.0218
Echinococcus granulosus carboxylesterase 5A 0.1319 0.4874 0.4874
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0052 0.0132 0.061
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Brugia malayi neuropeptide F receptor 0.0119 0.0384 0.054
Onchocerca volvulus 0.0119 0.0384 0.0455
Schistosoma mansoni growth hormone secretagogue receptor 0.0119 0.0384 0.0384
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0204 0.1456
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0225 0.0316
Echinococcus multilocularis lamin 0.0024 0.0029 0.0029
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0712 0.2604 0.426
Echinococcus multilocularis dna polymerase eta 0.0066 0.0184 0.0184
Onchocerca volvulus 0.01 0.0312 0.0365
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus multilocularis sex peptide receptor 0.0119 0.0384 0.0384
Schistosoma mansoni amine GPCR 0.0119 0.0384 0.0384
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Onchocerca volvulus 0.0033 0.0061 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0204 0.2519
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0126 0.0683
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.1365 0.5049 0.5049
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0016 0.0023
Brugia malayi hypothetical protein 0.0073 0.021 0.0295
Loa Loa (eye worm) hypothetical protein 0.0109 0.0346 0.0486
Echinococcus granulosus serine protein kinase ATM 0.0052 0.0132 0.0132
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus granulosus leukotriene A 4 hydrolase 0.1365 0.5049 0.5049
Echinococcus granulosus g protein coupled receptor 0.0119 0.0384 0.0384
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0016 0.0061
Giardia lamblia PHD finger protein 15 0.0325 0.1153 0.3302
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0368 0.0583
Loa Loa (eye worm) hypothetical protein 0.0077 0.0225 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0095 0.011
Mycobacterium tuberculosis Conserved protein 0.0077 0.0225 0.1244
Brugia malayi GnHR receptor homolog 0.0119 0.0384 0.054
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0073 0.021 0.1728
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0017 0.0014
Echinococcus granulosus adam 0.0025 0.0034 0.0034
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0106 0.0335 0.1645
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Entamoeba histolytica aminopeptidase, putative 0.0073 0.021 0.0324
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0065 0.0181 0.0254
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0276 0.097 0.097
Onchocerca volvulus 0.0119 0.0384 0.0455
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0228 0.0792 0.2258
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Echinococcus granulosus neuropeptide FF receptor 2 0.0119 0.0384 0.0384
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0115 0.0368 0.181
Loa Loa (eye worm) leukotriene A4 hydrolase 0.1365 0.5049 0.7093
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0119 0.0384 0.0384
Echinococcus multilocularis phd:f box containing protein 0.0119 0.0383 0.0383
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0016 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0225 0.2794
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Brugia malayi hypothetical protein 0.0018 0.0005 0.0007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.012 0.0389 0.0389
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1909 0.7083 0.7083
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0104 0.0327 0.046
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0088 0.0382
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0383 0.0539
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0828 0.3037 0.3037
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0023 0.0026 0.0021
Brugia malayi AF-10 protein 0.0106 0.0335 0.0471
Plasmodium falciparum T-complex protein 1 subunit beta 0.0023 0.0026 0.0144
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0119 0.0384 0.0384
Onchocerca volvulus 0.0119 0.0384 0.0455
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0225 0.1244
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0165 0.0165
Echinococcus granulosus Tolloid protein 1 0.0065 0.0181 0.0181
Echinococcus granulosus 7tm_1 domain containing protein 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0077 0.0225 0.0316
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0943 0.3466 0.3466
Echinococcus multilocularis JmjC domain containing protein 4 0.0119 0.0383 0.0383
Schistosoma mansoni hypothetical protein 0.0104 0.0327 0.0327
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0052 0.0132 0.0197
Brugia malayi Dopamine receptor protein 1 0.0119 0.0384 0.054
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0225 1
Echinococcus granulosus tm gpcr rhodopsin 0.0119 0.0384 0.0384
Echinococcus granulosus acetylcholinesterase 0.1319 0.4874 0.4874
Echinococcus multilocularis expressed protein 0.0032 0.006 0.006
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0057 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Giardia lamblia Tenascin-37 0.0025 0.0034 0.006
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Echinococcus multilocularis neuropeptide receptor 0.0119 0.0384 0.0384
Onchocerca volvulus Slit protein homolog 0.0025 0.0031 0.0018
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus multilocularis acetylcholinesterase 0.1319 0.4874 0.4874
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0023 0.0026 0.0021
Echinococcus granulosus lysine specific demethylase 6a 0.0119 0.0383 0.0383
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0041 0.0047
Echinococcus multilocularis G protein coupled receptor 139 0.0119 0.0384 0.0384
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0119 0.0383 0.0609
Echinococcus multilocularis chromobox protein 1 0.0075 0.0218 0.0218
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0119 0.0384 0.0384
Schistosoma mansoni jumonji/arid domain-containing protein 0.0447 0.1612 0.1612
Echinococcus multilocularis notch 0.0025 0.0031 0.0031
Loa Loa (eye worm) beta-lactamase 0.0077 0.0225 0.0316
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.016 0.1937
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Echinococcus multilocularis fmrfamide receptor 0.0119 0.0384 0.0384
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0225 0.0225
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0228 0.0792 0.0792
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Brugia malayi G-protein coupled receptor 0.0119 0.0384 0.054
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0204 0.0287
Echinococcus multilocularis somatostatin receptor 0.0119 0.0384 0.0384
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0228 0.0792 0.1282
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0052 0.0132 0.061
Brugia malayi jmjC domain containing protein 0.0119 0.0383 0.0539
Onchocerca volvulus 0.0119 0.0384 0.0455
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0115 0.0368 0.0517
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0119 0.0384 0.0384
Brugia malayi PHD-finger family protein 0.0108 0.0341 0.0479
Schistosoma mansoni neuropeptide receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Schistosoma mansoni hypothetical protein 0.0502 0.1816 0.1816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0312 0.0438
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0225 0.2794
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.1645 0.6096 0.7515
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0132 0.0197
Loa Loa (eye worm) hypothetical protein 0.0053 0.0137 0.0192
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Leishmania major DNA polymerase kappa, putative 0.004 0.0088 0.057
Loa Loa (eye worm) hypothetical protein 0.0617 0.2248 0.3158
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Brugia malayi Kelch motif family protein 0.012 0.0387 0.0544
Leishmania major phosphatidylinositol kinase, putative 0.0052 0.0132 0.091
Loa Loa (eye worm) hypothetical protein 0.0053 0.0137 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0115 0.0368 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Schistosoma mansoni opsin-like receptor 0.0119 0.0384 0.0384
Echinococcus granulosus protein jagged 1 0.0025 0.0031 0.0031
Trypanosoma brucei hypothetical protein, conserved 0.0115 0.0368 0.181
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1645 0.6096 0.8564
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0052 0.0132 0.0132
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0368 0.1317 0.1317
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0276 0.097 0.097
Echinococcus granulosus neuroligin 0.0223 0.0772 0.0772
Treponema pallidum bacterioferrin (TpF1) 0.0025 0.0031 1
Onchocerca volvulus 0.0119 0.0384 0.0455
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0828 0.3037 0.4266
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0041 0.0145
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0137 0.5
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0073 0.021 0.1499
Echinococcus granulosus orexin receptor type 2 0.0119 0.0384 0.0384
Brugia malayi hypothetical protein 0.012 0.0387 0.0544
Echinococcus multilocularis neuropeptide FF receptor 2 0.0119 0.0384 0.0384
Echinococcus granulosus geminin 0.0502 0.1816 0.1816
Onchocerca volvulus 0.0025 0.0031 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0016 0.0061
Plasmodium vivax JmjC domain containing protein 0.0119 0.0383 0.3249
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0084 0.0254 0.0254
Echinococcus multilocularis allatostatin A receptor 0.0119 0.0384 0.0384
Entamoeba histolytica hypothetical protein 0.0052 0.0132 0.0197
Echinococcus granulosus allatostatin A receptor 0.0119 0.0384 0.0384
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0016 0.0061
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0031 0.0031
Leishmania major hypothetical protein, conserved 0.0077 0.0225 0.1615
Echinococcus multilocularis acetylcholinesterase 0.1319 0.4874 0.4874
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0031 0.0043
Schistosoma mansoni amine GPCR 0.0119 0.0384 0.0384
Echinococcus granulosus neuropeptide receptor 0.0119 0.0384 0.0384
Echinococcus granulosus importin subunit beta 1 0.0026 0.0036 0.0036
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0119 0.0384 0.0384
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0041 0.0082
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0165 0.2004
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0223 0.0772 0.4346
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.016 0.016
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.3113
Echinococcus multilocularis jumonji domain containing 1A 0.0119 0.0383 0.0383
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0041 0.0278
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Echinococcus granulosus protein jagged 2 0.0025 0.0031 0.0031
Brugia malayi hypothetical protein 0.0073 0.021 0.0295
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0016 0.0047
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus multilocularis musashi 0.0024 0.0029 0.0029
Schistosoma mansoni rotamase 0.0032 0.006 0.006
Onchocerca volvulus 0.0073 0.021 0.0239
Loa Loa (eye worm) hypothetical protein 0.0982 0.3613 0.5076
Loa Loa (eye worm) integrin beta-2 0.0677 0.2473 0.3475
Echinococcus granulosus peptide allatostatin:somatostatin 0.0119 0.0384 0.0384
Onchocerca volvulus 0.0025 0.0031 0.0018
Schistosoma mansoni histamine h1 receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Schistosoma mansoni apoferritin-2 0.0025 0.0031 0.0031
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.1593 0.5902 0.9681
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0204 0.0287
Schistosoma mansoni hypothetical protein 0.005 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Plasmodium falciparum phosphodiesterase gamma, putative 0.0115 0.0368 0.3133
Echinococcus granulosus g protein coupled receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0119 0.0384 0.054
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0088 0.0088
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0031 0.0043
Loa Loa (eye worm) carboxylesterase 0.0223 0.0772 0.1085
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0492 0.178 0.2905
Echinococcus multilocularis g protein coupled receptor 0.0119 0.0384 0.0384
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0052 0.0132 0.061
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0132 0.0186
Loa Loa (eye worm) T-complex protein 1 0.0023 0.0026 0.0036
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0025 0.0031 1
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0073 0.021 0.021
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0088 0.057
Echinococcus multilocularis leukotriene A 4 hydrolase 0.1365 0.5049 0.5049
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0106 0.0335 0.0934
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0016 0.0013
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0107 0.0125
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0115 0.0368 0.0517
Schistosoma mansoni egf-like domain protein 0.0065 0.0181 0.0181
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0225 0.0225
Echinococcus granulosus hypothetical protein 0.0119 0.0384 0.0384
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0204 0.2519
Schistosoma mansoni slit 0.0025 0.0031 0.0031
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0204 0.1126
Loa Loa (eye worm) peptidase family M1 containing protein 0.0073 0.021 0.0295
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Onchocerca volvulus 0.0119 0.0384 0.0455
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0225 0.1082
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0108 0.0341 0.2902
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0053
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Mycobacterium ulcerans aminopeptidase N PepN 0.0073 0.021 0.2594
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Trichomonas vaginalis esterase, putative 0.0077 0.0225 0.027
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0088 0.0986
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.0184 0.0872
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0053 0.0137 0.0192
Mycobacterium leprae Probable lipase LipE 0.0077 0.0225 1
Loa Loa (eye worm) neuropeptide F receptor 0.0119 0.0384 0.054
Echinococcus granulosus biogenic amine 5HT receptor 0.0119 0.0384 0.0384
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0057 0.0073
Loa Loa (eye worm) jmjC domain-containing protein 0.067 0.2447 0.3437
Brugia malayi intermediate filament protein 0.0024 0.0029 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Schistosoma mansoni hypothetical protein 0.0052 0.0132 0.0132
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0057 0.0128
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0052 0.0132 0.0132
Toxoplasma gondii EGF family domain-containing protein 0.0025 0.0031 0.0052
Schistosoma mansoni hypothetical protein 0.0048 0.0118 0.0118
Brugia malayi Peptidase family M1 containing protein 0.0073 0.021 0.0295
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0052 0.0132 0.0132
Onchocerca volvulus 0.0119 0.0384 0.0455
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0031 0.0031
Giardia lamblia Tenascin precursor 0.0025 0.0034 0.006
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0115 0.0368 0.0446
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0943 0.3466 1
Brugia malayi Integrin alpha cytoplasmic region family protein 0.005 0.0126 0.0177
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0052 0.0132 0.0197
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0052 0.0132 0.061
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0016 0.0013
Toxoplasma gondii HEAT repeat-containing protein 0.0026 0.0036 0.0066
Brugia malayi Bromodomain containing protein 0.0325 0.1153 0.162
Loa Loa (eye worm) hypothetical protein 0.0108 0.0341 0.0479
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0371 0.1327 0.1864
Echinococcus multilocularis fibrillin 1 0.009 0.0276 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0225 0.0349
Brugia malayi hypothetical protein 0.0027 0.0041 0.0058
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trypanosoma cruzi aminopeptidase, putative 0.0073 0.021 0.0324
Trypanosoma brucei Aminopeptidase M1, putative 0.0073 0.021 0.1005
Loa Loa (eye worm) hypothetical protein 0.0077 0.0225 0.0316
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0132 0.0186
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Brugia malayi Integrin alpha pat-2 precursor 0.0105 0.033 0.0464
Echinococcus granulosus delta-like protein 1 0.0025 0.0031 0.0031
Echinococcus multilocularis serotonin receptor 0.0119 0.0384 0.0384
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1329 0.4914 0.8057
Entamoeba histolytica hypothetical protein 0.0032 0.006 0.0077
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0025 0.0031 0.0707
Trypanosoma brucei aminopeptidase, putative 0.0073 0.021 0.1005
Brugia malayi TATA binding protein associated factor 0.0073 0.021 0.0295
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0052 0.0132 0.0197
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0119 0.0384 0.0384
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.3133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis set domain proteins, putative 0.2183 0.811 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0073 0.021 0.0324
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0132 0.1049
Loa Loa (eye worm) hypothetical protein 0.0489 0.177 0.2486
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus granulosus alpha 1A adrenergic receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0065 0.0181 0.0254
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0115 0.0368 0.0583
Schistosoma mansoni ferritin light chain 0.0025 0.0031 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0204 0.1126
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0544 0.1974 0.2428
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0119 0.0384 0.054
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0052 0.0132 0.091
Echinococcus granulosus neuropeptide s receptor 0.0533 0.1935 0.1935
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.0197
Schistosoma mansoni DNA polymerase eta 0.0066 0.0184 0.0184
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0023 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0023
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.3113
Trypanosoma brucei C-8 sterol isomerase, putative 0.0371 0.1327 0.6701
Echinococcus granulosus tachykinin peptides receptor 99D 0.0119 0.0384 0.0384
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.006 0.006
Brugia malayi jmjC domain containing protein 0.0119 0.0383 0.0539
Echinococcus granulosus somatostatin receptor 0.0119 0.0384 0.0384
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0054 0.0142 0.02
Brugia malayi neuropeptide F receptor 0.0119 0.0384 0.054
Schistosoma mansoni ferritin 0.0025 0.0031 0.0031
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0081 0.0197
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0228 0.0792 0.097
Mycobacterium tuberculosis Conserved protein 0.0077 0.0225 0.1244
Loa Loa (eye worm) hypothetical protein 0.0371 0.1327 0.1864
Loa Loa (eye worm) kelch domain-containing protein family protein 0.012 0.0387 0.0544
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Brugia malayi GCC2 and GCC3 family protein 0.0025 0.0031 0.0043
Brugia malayi hypothetical protein 0.0223 0.0772 0.1085
Onchocerca volvulus 0.0077 0.0225 0.0258
Schistosoma mansoni biogenic amine receptor 0.0119 0.0384 0.0384
Echinococcus granulosus dnaJ subfamily B 0.0368 0.1317 0.1317
Loa Loa (eye worm) hypothetical protein 0.1319 0.4874 0.6847
Brugia malayi Cadherin domain containing protein 0.0025 0.0031 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) TATA binding protein associated factor 0.0073 0.021 0.0295
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0073 0.021 0.0324
Giardia lamblia Tenascin-X 0.0025 0.0034 0.006
Onchocerca volvulus Huntingtin homolog 0.0134 0.044 0.0524
Loa Loa (eye worm) hypothetical protein 0.0073 0.021 0.0295
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Echinococcus multilocularis jumonji domain containing protein 0.0452 0.1629 0.1629
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0026 0.0026
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0016 0.0061
Onchocerca volvulus Neurogenic locus notch homolog 0.0025 0.0031 0.0018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0017 0.0014
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.006 0.006
Echinococcus multilocularis g protein coupled receptor 0.0119 0.0384 0.0384
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0016 0.0047
Loa Loa (eye worm) phosphatidylinositol 3 0.0492 0.178 0.2501
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0132 0.091
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Mycobacterium ulcerans carboxylesterase, LipT 0.0223 0.0772 1
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0052 0.0132 0.0132
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0204 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0081 0.0112
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0016 0.0006
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1909 0.7083 0.7083
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0041 0.0145
Toxoplasma gondii aminopeptidase n, putative 0.0073 0.021 0.0571
Trypanosoma cruzi importin beta-1 subunit, putative 0.0021 0.0017 0.0007
Trichomonas vaginalis rotamase, putative 0.0032 0.006 0.0066
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0013 0.0013
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0228 0.0792 0.1282
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0276 0.097 0.097
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Brugia malayi MH2 domain containing protein 0.0242 0.0843 0.1184
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0052 0.0132 0.0132
Schistosoma mansoni hypothetical protein 0.0119 0.0384 0.0384
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0057 0.0073
Echinococcus granulosus neuropeptide receptor A26 0.0533 0.1935 0.1935
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0544 0.1974 0.3224
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0023 0.0026 0.0115
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0016 0.0023
Brugia malayi Delta serrate ligand family protein 0.0025 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.005 0.0126 0.0177
Loa Loa (eye worm) aminopeptidase N 0.0073 0.021 0.0295
Loa Loa (eye worm) hypothetical protein 0.0115 0.0368 0.0517
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0137 0.1115
Brugia malayi Carboxylesterase family protein 0.1319 0.4874 0.6847
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0052 0.0132 0.1049
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0119 0.0384 0.054
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.1028 0.3786 0.3786
Onchocerca volvulus 0.0223 0.0772 0.0934
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Leishmania major hypothetical protein, conserved 0.0052 0.0132 0.091
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0115 0.0368 0.3133
Toxoplasma gondii PHD-finger domain-containing protein 0.0325 0.1153 0.3302
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Entamoeba histolytica hypothetical protein 0.0032 0.006 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0383 0.0539
Loa Loa (eye worm) hypothetical protein 0.0048 0.0118 0.0166
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0041 0.0145
Echinococcus granulosus protein jagged 1 0.0025 0.0031 0.0031
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0119 0.0384 0.0384
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0088 0.0466
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0489 0.177 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0181 0.0254
Echinococcus granulosus integrin alpha ps 0.0105 0.033 0.033
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0016 0.0047
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.006 0.0084
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0132 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0119 0.0384 0.0384
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0659 0.0659
Onchocerca volvulus 0.0077 0.0225 0.0258
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni amine GPCR 0.0119 0.0384 0.0384
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Echinococcus multilocularis survival motor neuron protein 1 0.0489 0.177 0.177
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0223 0.0772 0.0946
Echinococcus multilocularis neuropeptide receptor A26 0.0533 0.1935 0.1935
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0025 0.0031 0.0043
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0025 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.016 0.0426
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0115 0.0368 0.2701
Echinococcus granulosus GPCR family 2 0.0048 0.0118 0.0118
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0165 0.0165
Echinococcus multilocularis 0.0052 0.0132 0.0132
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.287 0.287
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Toxoplasma gondii t-complex protein beta subunit 0.0023 0.0026 0.0038
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0025 0.0031 0.0145
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Schistosoma mansoni biogenic amine (5HT) receptor 0.0119 0.0384 0.0384
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0013 0.0008
Echinococcus multilocularis aminopeptidase N 0.0073 0.021 0.021
Echinococcus multilocularis fat cadherin tumor suppressor 0.0025 0.0031 0.0031
Toxoplasma gondii aminopeptidase N protein 0.0073 0.021 0.0571
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0016 0.0023
Onchocerca volvulus 0.0073 0.021 0.0239
Echinococcus granulosus neuropeptides capa receptor 0.0119 0.0384 0.0384
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0115 0.0368 0.0583
Brugia malayi Carboxylesterase family protein 0.1319 0.4874 0.6847
Echinococcus granulosus BC026374 protein S09 family 0.0223 0.0772 0.0772
Loa Loa (eye worm) G-protein coupled receptor 0.0119 0.0384 0.054
Brugia malayi Fibulin-1 precursor 0.0065 0.0181 0.0254
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.181
Loa Loa (eye worm) hypothetical protein 0.0054 0.0142 0.02
Onchocerca volvulus 0.0223 0.0772 0.0934
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0036 0.0116
Schistosoma mansoni hypothetical protein 0.0106 0.0335 0.0335
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Loa Loa (eye worm) hypothetical protein 0.0276 0.097 0.1363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Brugia malayi Dopamine receptor protein 2 0.0119 0.0384 0.054
Giardia lamblia Hypothetical protein 0.0115 0.0368 0.1028
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0115 0.0368 0.181
Schistosoma mansoni integrin alpha-ps 0.0105 0.033 0.033
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0088 0.0101
Echinococcus granulosus 7TM GPCR rhodopsin 0.0119 0.0384 0.0384
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0943 0.3466 0.3466
Brugia malayi Cadherin domain containing protein 0.0025 0.0031 0.0043
Onchocerca volvulus 0.0071 0.0204 0.0232
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Onchocerca volvulus 0.0223 0.0772 0.0934
Onchocerca volvulus 0.0024 0.0029 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0132 0.0132
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0115 0.0368 0.0583
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0016 0.0023
Brugia malayi Pre-SET motif family protein 0.1918 0.7118 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.1116 0.4115 0.4115
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0368 0.0446
Echinococcus multilocularis GPCR, family 2 0.0048 0.0118 0.0118
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0115 0.0368 0.0368
Schistosoma mansoni notch 0.0025 0.0031 0.0031
Echinococcus multilocularis g protein coupled receptor 0.0119 0.0384 0.0384
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0029 0.0041
Brugia malayi beta-lactamase family protein 0.0077 0.0225 0.0316
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni ferritin light chain 0.0025 0.0031 0.0031
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0052 0.0132 0.0197
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0204 0.2519
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0095 0.011
Brugia malayi Peptidase family M1 containing protein 0.0073 0.021 0.0295
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Leishmania major hypothetical protein, unknown function 0.0052 0.0132 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0132 0.0156
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0052 0.0132 0.0156
Giardia lamblia DINP protein human, muc B family 0.004 0.0088 0.0217
Loa Loa (eye worm) hypothetical protein 0.0325 0.1153 0.162
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Brugia malayi putative neuropeptide receptor NPR1 0.0119 0.0384 0.054
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Brugia malayi Calcium binding EGF domain containing protein 0.0065 0.0181 0.0254
Loa Loa (eye worm) hypothetical protein 0.0152 0.0507 0.0713
Echinococcus granulosus fibropellin Ia 0.0025 0.0031 0.0031
Echinococcus granulosus laminin 0.0065 0.0181 0.0181
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0016 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.0026 0.0035 0.0049
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0115 0.0368 0.0368
Echinococcus multilocularis neural cadherin 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0039
Loa Loa (eye worm) hypothetical protein 0.019 0.0648 0.0911
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0073 0.021 0.0324
Trypanosoma cruzi aminopeptidase, putative 0.0073 0.021 0.0324
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0031 0.0031
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0025 0.0034 0.0034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.0507 0.0713
Loa Loa (eye worm) hypothetical protein 0.0077 0.0225 0.0316
Echinococcus multilocularis protein jagged 1 0.0025 0.0031 0.0031
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0132 0.0186
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Schistosoma mansoni apoferritin-2 0.0025 0.0031 0.0031
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Giardia lamblia Neurogenic locus Notch protein precursor 0.0025 0.0034 0.006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0204 0.0287
Giardia lamblia Phosphatidylinositol 4-kinase 0.0052 0.0132 0.0346
Loa Loa (eye worm) hypothetical protein 0.0042 0.0095 0.0134
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0016 0.0047
Brugia malayi Carboxylesterase family protein 0.0223 0.0772 0.1085
Loa Loa (eye worm) hypothetical protein 0.0223 0.0772 0.1085
Echinococcus multilocularis G-protein coupled receptor, putative 0.0119 0.0384 0.0384
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0052 0.0132 0.061
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0066 0.0184 0.0258
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0218 0.0262
Onchocerca volvulus 0.0024 0.0029 0.0016
Onchocerca volvulus Huntingtin homolog 0.0134 0.044 0.0524
Giardia lamblia High cysteine protein 0.0025 0.0031 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0132 0.0186
Echinococcus granulosus JmjC domain containing protein 4 0.0119 0.0383 0.0383
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0119 0.0384 0.0384
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0071 0.0204 0.0287
Echinococcus multilocularis fibropellin Ia 0.0025 0.0031 0.0031
Echinococcus granulosus expressed protein 0.0032 0.006 0.006
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0845 0.3102 0.8946
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0193 0.0659 0.0926
Plasmodium falciparum importin beta, putative 0.0026 0.0036 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Echinococcus multilocularis PHD finger protein rhinoceros 0.0325 0.1153 0.1153
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0132 0.0186
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0025 0.0031 0.0018
Echinococcus multilocularis lysine specific demethylase 5A 0.0446 0.1607 0.1607
Echinococcus multilocularis neuropeptides capa receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis integrin alpha ps 0.005 0.0126 0.0126
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0115 0.0368 0.1028
Giardia lamblia hypothetical protein 0.0115 0.0368 0.1028
Schistosoma mansoni chromobox protein 0.0075 0.0218 0.0218
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.3113
Schistosoma mansoni opsin-like receptor 0.0119 0.0384 0.0384
Schistosoma mansoni ap endonuclease 0.002 0.0013 0.0013
Echinococcus granulosus fibrillin 1 0.0025 0.0034 0.0034
Brugia malayi notch-like transmembrane receptor 0.0025 0.0031 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0119 0.0384 0.0384
Toxoplasma gondii PHD-finger domain-containing protein 0.0106 0.0335 0.0934
Echinococcus multilocularis slit 2 protein 0.0025 0.0031 0.0031
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.0507 0.0713
Echinococcus multilocularis protein jagged 1 0.0025 0.0031 0.0031
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0119 0.0384 0.0384
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0204 0.2519
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Schistosoma mansoni phosphatidylserine receptor 0.0119 0.0383 0.0383
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0119 0.0384 0.0384
Onchocerca volvulus 0.0025 0.0034 0.0021
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0264 0.0926 0.13
Onchocerca volvulus 0.0029 0.0046 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.181
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1909 0.7083 0.7083
Toxoplasma gondii target of rapamycin (TOR), putative 0.0052 0.0132 0.0346
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0047
Brugia malayi Carboxylesterase family protein 0.0223 0.0772 0.1085
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0118 0.0166
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Brugia malayi EGF-like domain containing protein 0.0025 0.0034 0.0047
Schistosoma mansoni cpg binding protein 0.0027 0.0041 0.0041
Echinococcus multilocularis Tolloid protein 1 0.0065 0.0181 0.0181
Schistosoma mansoni integrin alpha-ps 0.0054 0.0142 0.0142
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0193 0.0659 0.0659
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.1028 0.3786 0.3786
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0544 0.1974 0.1974
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Loa Loa (eye worm) hypothetical protein 0.0071 0.0204 0.0287
Echinococcus multilocularis neurogenic locus notch protein 4 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.1028 0.3786 0.5319
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0184 0.0281
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Plasmodium vivax hypothetical protein 0.0052 0.0132 0.1049
Leishmania major phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.091
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0118 0.0166
Onchocerca volvulus 0.0119 0.0384 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Brugia malayi jmjC domain containing protein 0.0447 0.1612 0.2265
Echinococcus granulosus integrin alpha ps 0.005 0.0126 0.0126
Onchocerca volvulus 0.0288 0.1016 0.1235
Schistosoma mansoni lamin 0.0024 0.0029 0.0029
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0052 0.0132 0.0197
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0016 0.0023
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0065 0.0181 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus multilocularis laminin 0.0065 0.0181 0.0181
Echinococcus granulosus neurogenic locus notch protein 4 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0052 0.0132 0.0346
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0048 0.0118 0.0118
Brugia malayi G protein-coupled receptor 0.0119 0.0384 0.054
Schistosoma mansoni notch 0.0025 0.0031 0.0031
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0073 0.021 0.1753
Schistosoma mansoni hypothetical protein 0.0119 0.0384 0.0384
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Leishmania major C-8 sterol isomerase-like protein 0.0371 0.1327 1
Brugia malayi hypothetical protein 0.0489 0.177 0.2486
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0137 0.0745
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.016 0.016
Toxoplasma gondii aminopeptidase N, putative 0.0073 0.021 0.0571
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0132 0.0186
Echinococcus granulosus histone lysine methyltransferase setb 0.0276 0.097 0.097
Echinococcus granulosus acetylcholinesterase 0.1319 0.4874 0.4874
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0115 0.0368 0.0446
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0016 0.0047
Brugia malayi chromobox protein homolog 3 0.0042 0.0095 0.0134
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0031 0.0043
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0016 0.0047
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.061
Loa Loa (eye worm) carboxylesterase 0.0223 0.0772 0.1085
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Echinococcus granulosus snurportin 1 0.0277 0.0976 0.0976
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0016 0.0061
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.0086
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0065 0.0181 0.0254
Schistosoma mansoni neuropeptide f receptor 76f 0.0119 0.0384 0.0384
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0228 0.0792 0.1113
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0228 0.0792 0.1113
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0223 0.0772 0.0772
Echinococcus multilocularis integrin alpha 3 0.005 0.0126 0.0126
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0225 0.0225
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0088 0.0123
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0016 0.0023
Schistosoma mansoni hypothetical protein 0.01 0.0312 0.0312
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0052 0.0132 0.0197
Schistosoma mansoni importin beta-1 0.0026 0.0036 0.0036
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.1049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0544 0.1974 0.2428
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.0384 0.0384
Echinococcus multilocularis carboxylesterase 5A 0.1319 0.4874 0.4874
Plasmodium falciparum phd finger protein, putative 0.0325 0.1153 1
Giardia lamblia High cysteine protein 0.0025 0.0034 0.006
Schistosoma mansoni neuropeptide F-like receptor 0.0119 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0052 0.0132 0.0186
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0228 0.0792 0.0792
Loa Loa (eye worm) TYRA-2 protein 0.0119 0.0384 0.054
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0073 0.021 0.021
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0107 0.0112
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0088 0.0123
Echinococcus multilocularis protein jagged 2 0.0025 0.0034 0.0034
Brugia malayi hypothetical protein 0.0119 0.0384 0.054
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0031 0.0031
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0052 0.0132 0.0132
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0026 0.0026
Loa Loa (eye worm) RecQ helicase 0.0022 0.0019 0.0027
Echinococcus granulosus chromobox protein 1 0.0075 0.0218 0.0218
Giardia lamblia Hypothetical protein 0.0052 0.0132 0.0346
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0341 0.2881
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0016 0.0047
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0119 0.0383 0.1073
Echinococcus granulosus bloom syndrome protein 0.0022 0.0019 0.0019
Leishmania major importin beta-1 subunit, putative 0.0021 0.0017 0.0033
Echinococcus multilocularis orexin receptor type 2 0.0119 0.0384 0.0384
Plasmodium falciparum phosphodiesterase delta, putative 0.0115 0.0368 0.3133
Trypanosoma brucei unspecified product 0.0028 0.0041 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Brugia malayi Carboxylesterase family protein 0.0223 0.0772 0.1085
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0052 0.0132 0.0156
Loa Loa (eye worm) notch protein 0.0025 0.0031 0.0043
Onchocerca volvulus 0.0025 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Entamoeba histolytica hypothetical protein 0.0021 0.0017 0.0007
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0073 0.021 0.1753
Loa Loa (eye worm) hypothetical protein 0.0071 0.0204 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.006 0.0066
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) PHD-finger family protein 0.0325 0.1153 0.162
Brugia malayi hypothetical protein 0.0442 0.1592 0.2236
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0115 0.0368 0.0446
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0327 0.046
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0132 0.0197
Echinococcus granulosus tm gpcr rhodopsin 0.0119 0.0384 0.0384
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0073 0.021 0.1005
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0115 0.0368 0.0517
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0119 0.0383 0.0609
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0223 0.0772 0.0772
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0115 0.0368 0.0368
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0119 0.0384 0.0384
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Leishmania major hypothetical protein, conserved 0.0115 0.0368 0.2701
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0016 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0119 0.0384 0.0384
Mycobacterium tuberculosis Conserved hypothetical protein 0.0052 0.0132 0.0719
Giardia lamblia High cysteine protein 0.0025 0.0034 0.006
Loa Loa (eye worm) hypothetical protein 0.0077 0.0225 0.0316
Echinococcus multilocularis neuroligin 0.0223 0.0772 0.0772
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0165 0.1158
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0052 0.0132 0.061
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0019 0.0027
Schistosoma mansoni chromobox protein 0.0075 0.0218 0.0218
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0115 0.0368 0.0368
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0223 0.0772 0.4346
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0073 0.021 0.021
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Brugia malayi F/Y-rich N-terminus family protein 0.0124 0.0403 0.0566
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.016 0.016
Trypanosoma brucei unspecified product 0.004 0.0088 0.0382
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0115 0.0368 0.181
Loa Loa (eye worm) Notch2 0.0025 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0053 0.0137 0.0192
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0119 0.0384 0.0384
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0052 0.0132 0.0197
Onchocerca volvulus 0.0026 0.0035 0.0023
Toxoplasma gondii FATC domain-containing protein 0.0052 0.0132 0.0346
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0065 0.0181 0.0181
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0943 0.3466 0.3466
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0115 0.0368 0.0583
Echinococcus multilocularis neuropeptide Y receptor 0.0119 0.0384 0.0384
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0052 0.0132 0.091
Echinococcus multilocularis lysine specific demethylase 6a 0.0119 0.0383 0.0383
Echinococcus granulosus G protein coupled receptor 139 0.0119 0.0384 0.0384
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0026 0.0026
Brugia malayi EGF-like domain containing protein 0.0025 0.0034 0.0047
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0225 0.1244
Echinococcus granulosus intermediate filament protein 0.0024 0.0029 0.0029
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.016 0.0425
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0047
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0016 0.0061
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0052 0.0132 0.0346
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0119 0.0384 0.054
Onchocerca volvulus 0.0119 0.0384 0.0455
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0228 0.0792 0.2258
Schistosoma mansoni adenoreceptor 0.0119 0.0384 0.0384
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0115 0.0368 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0016 0.0006
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0943 0.3466 0.3466
Mycobacterium ulcerans hypothetical protein 0.0077 0.0225 0.2794
Brugia malayi EGF-like domain containing protein 0.0025 0.0031 0.0043
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.016 0.0875
Onchocerca volvulus 0.0119 0.0384 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0052 0.0132 0.0132
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0115 0.0368 0.0368
Brugia malayi Muscle positioning protein 4 0.0025 0.0031 0.0043
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0132 0.0197
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0013 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0132 0.0156
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.006 0.0084
Onchocerca volvulus 0.0119 0.0384 0.0455
Echinococcus granulosus tm gpcr rhodopsin 0.0119 0.0384 0.0384
Echinococcus multilocularis protein jagged 2 0.0025 0.0031 0.0031
Onchocerca volvulus 0.2183 0.811 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0088 0.0382
Schistosoma mansoni lamin 0.0024 0.0029 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0225 0.0349
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0043
Plasmodium falciparum JmjC domain-containing protein, putative 0.0119 0.0383 0.3269
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0277 0.0976 0.1371
Brugia malayi jmjC domain containing protein 0.1116 0.4115 0.5781
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Brugia malayi CXXC zinc finger family protein 0.0026 0.0035 0.0049
Mycobacterium ulcerans hypothetical protein 0.0071 0.0204 0.2519
Leishmania major DNA polymerase eta, putative 0.0038 0.0081 0.0518
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0115 0.0368 0.0368
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.0384 0.0384
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0132 0.061
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.054
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0088 0.0382
Echinococcus multilocularis g-protein coupled receptor 0.0119 0.0384 0.0384
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0276 0.097 0.2772
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0228 0.0792 0.097
Loa Loa (eye worm) G-protein coupled receptor 0.0119 0.0384 0.054
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0016 0.0061
Trichomonas vaginalis importin beta-1, putative 0.0021 0.0017 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.0119 0.0384 0.0384
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0115 0.0368 0.0368
Mycobacterium ulcerans hypothetical protein 0.0114 0.0367 0.4658

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) NA 0 Tested for antiviral activity against HIV-1 in MT-4 cells ChEMBL. 11229780
Activity (functional) NA 0 Tested for antiviral activity against HSV-1 in CCL 81 cells ChEMBL. 11229780
Activity (functional) NA 0 Tested for antiviral activity against HSV-2 in CCL 81 cells ChEMBL. 11229780
Activity (functional) SA 0 Tested for antiviral activity against HCMV in HELL 299 cells ChEMBL. 11229780

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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