Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0109 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0248 | 0.0882 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0014 | 0.0004 | 0.0023 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0412 | 0.2463 | 0.678 |
Onchocerca volvulus | 0.0041 | 0.0169 | 0.0599 | |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0109 | 0.025 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0031 | 0.0157 |
Brugia malayi | jmjC domain containing protein | 0.0116 | 0.0636 | 0.175 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0017 | 0.0048 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0031 | 0.0108 | 0.0298 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0057 | 0.0268 | 0.0627 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.018 | 0.092 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0054 | 0.0248 | 0.1266 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0374 | 0.1031 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0178 | 0.0633 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0074 | 0.0374 | 0.1304 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0694 | 0.4211 | 0.4209 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0074 | 0.0374 | 0.1304 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.196 | 0.5397 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0374 | 0.1331 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0108 | 0.0298 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0004 | 0.0012 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0141 | 0.0718 |
Schistosoma mansoni | patched 1 | 0.0136 | 0.0758 | 0.1791 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.0108 | 0.0298 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.033 | 0.196 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.0927 | 0.0923 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0374 | 0.1906 |
Brugia malayi | MAP kinase sur-1 | 0.0054 | 0.0248 | 0.0683 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0163 | 0.0927 | 0.2552 |
Onchocerca volvulus | 0.0163 | 0.0925 | 0.3285 | |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0141 | 0.0136 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0308 | 0.0721 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0333 | 0.0782 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0474 | 0.2848 | 0.2845 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0064 | 0.0303 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0049 | 0.0248 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0308 | 0.0721 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0141 | 0.0718 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0054 | 0.0248 | 0.1266 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0136 | 0.0758 | 0.2087 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.1479 |
Mycobacterium ulcerans | hypothetical protein | 0.016 | 0.0905 | 0.4602 |
Echinococcus multilocularis | smad | 0.0016 | 0.0017 | 0.0013 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0014 | 0.0004 | 0.0012 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0014 | 0.0004 | 0.0023 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0412 | 0.1134 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0282 | 0.0659 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0109 | 0.025 |
Schistosoma mansoni | lipoxygenase | 0.0058 | 0.0276 | 0.0645 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0054 | 0.0248 | 0.1266 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0374 | 0.1304 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.0927 | 0.0923 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0064 | 0.0176 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0064 | 0.0303 |
Brugia malayi | Inositol-1 | 0.0074 | 0.0374 | 0.1029 |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.035 | 0.0964 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.008 | 0.0412 | 0.2083 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Brugia malayi | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0136 | 0.0758 | 0.2693 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | carboxylesterase | 0.008 | 0.0412 | 0.1134 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0059 | 0.0282 | 0.0277 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0239 | 0.1395 | 0.3842 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0054 | 0.0248 | 0.0579 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0031 | 0.0134 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.033 | 0.196 | 0.4649 |
Loa Loa (eye worm) | doublecortin family protein | 0.0041 | 0.0169 | 0.0464 |
Schistosoma mansoni | smad | 0.0016 | 0.0017 | 0.0031 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0116 | 0.0636 | 0.15 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0089 | 0.0315 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0169 | 0.0464 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0031 | 0.012 |
Mycobacterium leprae | Probable lipase LipE | 0.0074 | 0.0374 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0058 | 0.0276 | 0.0645 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.0241 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0073 |
Onchocerca volvulus | 0.008 | 0.0412 | 0.1463 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.008 | 0.0412 | 0.1435 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0096 | 0.0489 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0041 | 0.0169 | 0.039 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0074 | 0.0374 | 0.1304 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0031 | 0.0157 |
Echinococcus granulosus | RUN | 0.0041 | 0.0169 | 0.039 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0041 | 0.0169 | 0.0164 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0475 | 0.2857 | 0.2854 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0031 | 0.0108 | 0.0247 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0017 | 0.0013 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0694 | 0.4211 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0073 |
Onchocerca volvulus | 0.0469 | 0.2814 | 1 | |
Brugia malayi | Pip kinase protein 2 | 0.0163 | 0.0925 | 0.2545 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.035 | 0.0822 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0163 | 0.0927 | 0.2193 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0064 | 0.0176 |
Onchocerca volvulus | 0.0031 | 0.0107 | 0.038 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0059 | 0.0282 | 0.7492 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.035 | 0.0822 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.0688 |
Echinococcus granulosus | acetylcholinesterase | 0.0474 | 0.2848 | 0.6759 |
Echinococcus multilocularis | geminin | 0.034 | 0.202 | 0.2016 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0041 | 0.0169 | 0.0164 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0178 | 0.0633 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0096 | 0.0218 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0031 | 0.0108 | 0.0247 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0064 | 0.0325 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0031 | 0.0108 | 0.0552 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0163 | 0.0925 | 0.2187 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0308 | 0.0303 |
Echinococcus granulosus | neuroligin | 0.008 | 0.0412 | 0.0968 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0017 | 0.0048 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0021 | 0.0057 |
Echinococcus granulosus | neuropeptide s receptor | 0.0451 | 0.2706 | 0.6422 |
Brugia malayi | Carboxylesterase family protein | 0.0474 | 0.2848 | 0.7841 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0031 | 0.071 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0014 | 0.0004 | 0.0023 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0333 | 0.0918 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0601 | 0.3632 | 0.3629 |
Echinococcus granulosus | muscleblind protein | 0.0601 | 0.3632 | 0.8623 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0074 | 0.0374 | 0.1328 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0169 | 0.0464 |
Brugia malayi | beta-lactamase | 0.0074 | 0.0374 | 0.1031 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0374 | 0.191 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0041 | 0.0169 | 0.039 |
Mycobacterium ulcerans | beta-lactamase | 0.0074 | 0.0374 | 0.1892 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0017 | 0.0048 |
Loa Loa (eye worm) | carboxylesterase | 0.0474 | 0.2848 | 0.7841 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0136 | 0.0758 | 0.1791 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0031 | 0.0108 | 0.0104 |
Echinococcus granulosus | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0163 | 0.0925 | 0.2187 |
Leishmania major | cytochrome p450-like protein | 0.0014 | 0.0004 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 0.2857 | 0.7866 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0096 | 0.4887 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0374 | 0.088 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0248 | 0.0882 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.008 | 0.0412 | 0.0968 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0049 | 0.0248 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0155 | 0.0875 | 0.311 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0163 | 0.0927 | 0.2552 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0374 | 0.1031 |
Brugia malayi | Carboxylesterase family protein | 0.0474 | 0.2848 | 0.7841 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0031 | 0.0108 | 0.0104 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0064 | 0.0209 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0374 | 0.1331 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0282 | 0.0659 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.008 | 0.0412 | 0.1463 |
Brugia malayi | RNA, U transporter 1 | 0.0083 | 0.0427 | 0.1175 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.016 | 0.0905 | 0.3172 |
Leishmania major | cytochrome p450-like protein | 0.0014 | 0.0004 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.1416 | 0.3898 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0074 | 0.0374 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0474 | 0.2848 | 0.7841 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0074 | 0.0374 | 0.1304 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0141 | 0.05 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0374 | 0.191 |
Onchocerca volvulus | 0.0041 | 0.0169 | 0.0599 | |
Schistosoma mansoni | gliotactin | 0.008 | 0.0412 | 0.0968 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0054 | 0.0248 | 0.0579 |
Echinococcus multilocularis | acetylcholinesterase | 0.0474 | 0.2848 | 0.2845 |
Onchocerca volvulus | 0.008 | 0.0412 | 0.1463 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0109 | 0.0105 |
Onchocerca volvulus | 0.0074 | 0.0374 | 0.1331 | |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0014 | 0.0004 | 0.0023 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.008 | 0.0412 | 0.0408 |
Schistosoma mansoni | ran | 0.0021 | 0.0049 | 0.0105 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.0786 | 0.1858 |
Onchocerca volvulus | Huntingtin homolog | 0.0242 | 0.1416 | 0.5031 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0074 | 0.0374 | 0.1304 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0031 | 0.0157 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0049 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0374 | 0.1031 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0248 | 0.0882 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.033 | 0.196 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0374 | 0.1331 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0097 | 0.0516 | 0.1421 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0374 | 0.1304 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0183 | 0.1048 | 0.2886 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0017 | 0.0048 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0694 | 0.4211 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0064 | 0.0209 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.008 | 0.0412 | 0.0968 |
Leishmania major | cytochrome p450-like protein | 0.0014 | 0.0004 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0017 | 0.0013 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0183 | 0.1048 | 0.2482 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0074 | 0.0374 | 0.1892 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0031 | 0.0108 | 0.0552 |
Onchocerca volvulus | 0.0074 | 0.0374 | 0.1331 | |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0031 | 0.0822 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.0134 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0178 | 0.0633 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0116 | 0.0636 | 0.15 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.0804 | 0.4103 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0017 | 0.0031 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0374 | 0.088 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0136 | 0.0758 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0374 | 0.1031 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.008 | 0.0412 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0109 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0116 | 0.0636 | 0.15 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.016 | 0.0439 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0014 | 0.0004 | 0.0012 |
Loa Loa (eye worm) | beta-lactamase | 0.0074 | 0.0374 | 0.1031 |
Schistosoma mansoni | inositol monophosphatase | 0.0074 | 0.0374 | 0.0878 |
Brugia malayi | cytochrome P450 | 0.0014 | 0.0004 | 0.0012 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0303 | 0.1792 | 0.9143 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0141 | 0.05 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0064 | 0.0303 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0451 | 0.2706 | 0.6422 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0116 | 0.0636 | 0.175 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0155 | 0.0875 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0017 | 0.0031 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.018 | 0.092 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054 | 0.0248 | 0.0579 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0108 | 0.0298 |
Trichomonas vaginalis | esterase, putative | 0.0074 | 0.0374 | 0.1331 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0089 | 0.0315 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0374 | 0.1906 |
Loa Loa (eye worm) | hypothetical protein | 0.0474 | 0.2848 | 0.7841 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0014 | 0.0004 | 0.0023 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0004 | 0.0012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0183 | 0.1048 | 0.2482 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0374 | 0.191 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0412 | 0.1134 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0141 | 0.05 |
Onchocerca volvulus | 0.0094 | 0.0501 | 0.178 | |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0155 | 0.0875 | 0.311 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.008 | 0.0412 | 0.1435 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.0688 |
Schistosoma mansoni | hypothetical protein | 0.034 | 0.202 | 0.4791 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0303 | 0.1792 | 0.9143 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0096 | 0.0264 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.008 | 0.0412 | 0.0408 |
Echinococcus multilocularis | snurportin 1 | 0.031 | 0.1832 | 0.1829 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0109 | 0.025 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0049 | 0.1193 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0031 | 0.0108 | 0.0247 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0374 | 0.1304 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0526 | 0.1449 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0294 | 0.0289 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0474 | 0.2848 | 0.7841 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0294 | 0.1498 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0308 | 0.0847 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.008 | 0.0412 | 0.1463 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0074 | 0.0374 | 0.1892 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0064 | 0.0176 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0064 | 0.1706 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0109 | 0.025 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0041 | 0.0169 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0412 | 0.1134 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0374 | 0.1331 |
Plasmodium vivax | hypothetical protein, conserved | 0.0074 | 0.0374 | 1 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0049 | 0.0248 |
Schistosoma mansoni | protein phosphatase 2C | 0.0031 | 0.0108 | 0.0247 |
Onchocerca volvulus | 0.0074 | 0.0374 | 0.1331 | |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0062 | 0.0316 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.0108 | 0.0298 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0144 | 0.0804 | 0.4103 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0064 | 0.1706 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0041 | 0.0169 | 0.039 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.7816 |
Brugia malayi | CHE-14 protein | 0.0136 | 0.0758 | 0.2087 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0141 | 0.05 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0141 | 0.05 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0308 | 0.0847 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0054 | 0.0248 | 0.6587 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0333 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.1416 | 0.3898 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.0238 | 0.1214 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.016 | 0.0567 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0031 | 0.0093 |
Echinococcus multilocularis | neuroligin | 0.008 | 0.0412 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0374 | 0.1031 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0066 | 0.0326 | 0.1132 |
Onchocerca volvulus | 0.008 | 0.0412 | 0.1463 | |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0014 | 0.0004 | 0.0023 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0062 | 0.022 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0141 | 0.0387 |
Echinococcus granulosus | smad | 0.0016 | 0.0017 | 0.0031 |
Echinococcus multilocularis | RUN | 0.0041 | 0.0169 | 0.0164 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0141 | 0.3682 |
Onchocerca volvulus | 0.008 | 0.0412 | 0.1463 | |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0108 | 0.0552 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.0526 | 0.1449 |
Brugia malayi | Doublecortin family protein | 0.0041 | 0.0169 | 0.0464 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0049 | 0.13 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0031 | 0.0293 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.0248 | 0.0882 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0096 | 0.0092 |
Schistosoma mansoni | acetylcholinesterase | 0.008 | 0.0412 | 0.0968 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0451 | 0.2706 | 0.2703 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0074 | 0.0374 | 0.1304 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0062 | 0.166 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0096 | 0.2473 |
Schistosoma mansoni | survival motor neuron protein | 0.0097 | 0.0516 | 0.1217 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0163 | 0.0925 | 0.2187 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0183 | 0.1048 | 0.1044 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0141 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0282 | 0.0776 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0141 | 0.0324 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0064 | 0.0325 |
Echinococcus multilocularis | protein patched | 0.0136 | 0.0758 | 0.0754 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0064 | 0.0325 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.0134 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0294 | 0.0688 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.0241 | 0.0665 |
Echinococcus granulosus | phd:f box containing protein | 0.0031 | 0.0108 | 0.0247 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0017 | 0.0048 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0141 | 0.0718 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0096 | 0.1995 |
Schistosoma mansoni | lipoxygenase | 0.0041 | 0.0169 | 0.039 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.1479 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0412 | 0.1134 |
Echinococcus granulosus | carboxylesterase 5A | 0.0474 | 0.2848 | 0.6759 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0136 | 0.0758 | 0.1791 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0054 | 0.0248 | 0.1266 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0136 | 0.0758 | 0.1791 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0155 | 0.0875 | 0.311 |
Loa Loa (eye worm) | carboxylesterase | 0.008 | 0.0412 | 0.1134 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0031 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0097 | 0.0516 | 0.1217 |
Loa Loa (eye worm) | hypothetical protein | 0.0601 | 0.3632 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0064 | 0.1706 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0303 | 0.1792 | 0.9143 |
Toxoplasma gondii | ABC1 family protein | 0.0074 | 0.0374 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0059 | 0.0282 | 0.0776 |
Schistosoma mansoni | hypothetical protein | 0.034 | 0.202 | 0.4791 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0064 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0064 | 0.0303 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.033 | 0.196 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0017 | 0.0031 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0282 | 0.0659 |
Plasmodium vivax | JmjC domain containing protein | 0.0031 | 0.0108 | 0.2348 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0059 | 0.0282 | 0.0659 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0064 | 0.1603 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0041 | 0.0169 | 0.4082 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.035 | 0.0822 |
Schistosoma mansoni | polycystin 1-related | 0.0041 | 0.0169 | 0.039 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0074 | 0.0374 | 0.088 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0054 | 0.0248 | 0.0244 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0374 | 0.1906 |
Trichomonas vaginalis | set domain proteins, putative | 0.0469 | 0.2814 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0017 | 0.0031 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.033 | 0.196 | 1 |
Onchocerca volvulus | 0.0071 | 0.0353 | 0.1253 | |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0925 | 0.2545 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0031 | 0.0109 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0183 | 0.1048 | 0.2482 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0141 | 0.05 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0054 | 0.0248 | 0.1266 |
Echinococcus multilocularis | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0163 | 0.0925 | 0.092 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0064 | 0.1603 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0031 | 0.0109 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.033 | 0.196 | 1 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.035 | 0.0822 |
Mycobacterium leprae | conserved hypothetical protein | 0.0074 | 0.0374 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0074 | 0.0374 | 0.1328 |
Brugia malayi | hypothetical protein | 0.0475 | 0.2857 | 0.7866 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0064 | 0.0303 |
Brugia malayi | Muscleblind-like protein | 0.0601 | 0.3632 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0109 | 0.0301 |
Schistosoma mansoni | jumonji domain containing protein | 0.0116 | 0.0636 | 0.15 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.1832 | 0.4345 |
Loa Loa (eye worm) | cytochrome P450 | 0.0014 | 0.0004 | 0.0012 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.033 | 0.196 | 0.4649 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0064 | 0.0176 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.0526 | 0.1449 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0183 | 0.1048 | 0.2482 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0064 | 0.0303 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0474 | 0.2848 | 0.6759 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0054 | 0.0248 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0064 | 0.0176 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0475 | 0.2857 | 0.6781 |
Echinococcus granulosus | acetylcholinesterase | 0.0474 | 0.2848 | 0.6759 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0027 | 0.0078 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0109 | 0.0105 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.016 | 0.0567 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0141 | 0.0718 |
Loa Loa (eye worm) | inositol-1 | 0.0074 | 0.0374 | 0.1029 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0064 | 0.0303 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0074 | 0.0374 | 0.0369 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0109 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0758 | 0.2087 |
Schistosoma mansoni | ran | 0.0021 | 0.0049 | 0.0105 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.0374 | 0.191 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0183 | 0.1048 | 0.2482 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0031 | 0.0108 | 0.5752 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0107 | 0.0295 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.008 | 0.0412 | 0.1435 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.008 | 0.0412 | 0.0408 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0031 | 0.0062 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0017 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0169 | 0.039 |
Echinococcus multilocularis | protein dispatched 1 | 0.0136 | 0.0758 | 0.0754 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0183 | 0.1048 | 0.2886 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.008 | 0.0412 | 0.0968 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.0108 | 0.0298 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0109 | 0.025 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0017 | 0.0013 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0031 | 0.0108 | 0.0247 |
Schistosoma mansoni | jumonji domain containing protein | 0.0031 | 0.0108 | 0.0247 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0031 | 0.0108 | 0.0298 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0308 | 0.0847 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.0108 | 0.0298 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0308 | 0.0721 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0308 | 0.0847 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.035 | 0.0346 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0031 | 0.0085 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0141 | 0.0324 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0116 | 0.0636 | 0.15 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0374 | 0.1892 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0109 | 0.0105 |
Onchocerca volvulus | Huntingtin homolog | 0.0242 | 0.1416 | 0.5031 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0031 | 0.5 |
Echinococcus multilocularis | phd:f box containing protein | 0.0031 | 0.0108 | 0.0104 |
Schistosoma mansoni | loxhd1 | 0.0041 | 0.0169 | 0.039 |
Echinococcus granulosus | snurportin 1 | 0.031 | 0.1832 | 0.4345 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0031 | 0.0108 | 0.0247 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.0804 | 0.4103 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0108 | 0.0298 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0054 | 0.0248 | 0.0244 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0031 | 0.0062 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0308 | 0.0847 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0031 | 0.0085 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.031 | 0.1832 | 0.5045 |
Brugia malayi | Pre-SET motif family protein | 0.0412 | 0.2463 | 0.678 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0374 | 0.1331 |
Mycobacterium ulcerans | lipase LipD | 0.0074 | 0.0374 | 0.1892 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0031 | 0.0157 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0074 | 0.0374 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0031 | 0.0108 | 0.0104 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0031 | 0.0108 | 0.0552 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0136 | 0.0758 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0169 | 0.0464 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.0219 | 0.58 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.016 | 0.0439 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.1019 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0031 | 0.0108 | 0.2805 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0096 | 0.0264 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0014 | 0.0004 | 0.0023 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0136 | 0.0758 | 0.0754 |
Brugia malayi | SET domain containing protein | 0.0014 | 0.0001 | 0.0002 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0041 | 0.0169 | 0.0164 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0059 | 0.0282 | 0.0277 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0308 | 0.0721 |
Echinococcus multilocularis | acetylcholinesterase | 0.0474 | 0.2848 | 0.2845 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.018 | 0.092 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.008 | 0.0412 | 0.0968 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0062 | 0.022 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.1552 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.035 | 0.0346 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.033 | 0.196 | 0.5397 |
Echinococcus granulosus | geminin | 0.034 | 0.202 | 0.4791 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0239 | 0.1395 | 0.3842 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0031 | 0.0108 | 0.0298 |
Trypanosoma brucei | cytochrome P450, putative | 0.0014 | 0.0004 | 0.0023 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0049 | 0.0173 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0021 | 0.0057 |
Schistosoma mansoni | phd/f-box containing protein | 0.0031 | 0.0108 | 0.0247 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.035 | 0.0964 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0109 | 0.0301 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0049 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0374 | 0.1031 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0109 | 0.025 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0027 | 0.5 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0017 | 0.0048 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0049 | 0.0105 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0014 | 0.0004 | 0.0012 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0096 | 0.0489 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0058 | 0.0276 | 0.0272 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0374 | 0.1031 |
Onchocerca volvulus | 0.008 | 0.0412 | 0.1463 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0074 | 0.0374 | 0.1304 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.035 | 0.1244 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.0786 | 0.1858 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0054 | 0.0248 | 0.1266 |
Trypanosoma brucei | protein kinase, putative | 0.0054 | 0.0248 | 0.1266 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0054 | 0.0248 | 0.2575 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0004 | 0.0012 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0074 | 0.0374 | 0.1328 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0074 | 0.0374 | 0.1906 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.016 | 0.0567 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0473 | 0.2843 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0031 | 0.0108 | 0.2805 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0303 | 0.1792 | 0.9143 |
Loa Loa (eye worm) | pip kinase 2 | 0.0163 | 0.0925 | 0.2545 |
Onchocerca volvulus | 0.0024 | 0.0064 | 0.0227 | |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0074 | 0.0374 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0308 | 0.0721 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0073 |
Schistosoma mansoni | inositol monophosphatase | 0.0074 | 0.0374 | 0.0878 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.033 | 0.196 | 0.1957 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0021 | 0.0057 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.008 | 0.0412 | 0.0968 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0062 | 0.022 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0021 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0374 | 0.1031 |
Plasmodium vivax | SET domain protein, putative | 0.0059 | 0.0282 | 0.7333 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0141 | 0.05 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0308 | 0.0847 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.018 | 0.092 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0049 | 0.0248 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0062 | 0.0316 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0294 | 0.1479 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0064 | 0.0176 |
Echinococcus granulosus | BC026374 protein S09 family | 0.008 | 0.0412 | 0.0968 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0451 | 0.2706 | 0.2703 |
Brugia malayi | hypothetical protein | 0.0242 | 0.1416 | 0.3898 |
Brugia malayi | Smad1 | 0.0016 | 0.0017 | 0.0048 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.008 | 0.0412 | 0.0968 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.035 | 0.1244 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0096 | 0.0218 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0031 | 0.0108 | 0.0104 |
Brugia malayi | jmjC domain containing protein | 0.0116 | 0.0636 | 0.175 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0066 | 0.0326 | 0.8682 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0116 | 0.0636 | 0.0631 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.0526 | 0.1449 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0074 | 0.0374 | 0.1031 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0031 | 0.0108 | 0.0247 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0141 | 0.3766 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0017 | 0.0031 |
Schistosoma mansoni | rab6-interacting | 0.0041 | 0.0169 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0412 | 0.1134 |
Brugia malayi | MH2 domain containing protein | 0.0239 | 0.1395 | 0.3842 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0116 | 0.0636 | 0.0631 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0017 | 0.0031 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0141 | 0.3766 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0141 | 0.05 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0074 | 0.0374 | 0.037 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0027 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0169 | 0.0464 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0074 | 0.0374 | 0.1031 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0054 | 0.0248 | 0.1266 |
Loa Loa (eye worm) | hypothetical protein | 0.0601 | 0.3632 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0601 | 0.3632 | 0.3629 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0141 | 0.0387 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0308 | 0.0721 |
Onchocerca volvulus | 0.0097 | 0.0516 | 0.1834 | |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0074 | 0.0374 | 0.1888 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0071 | 0.0353 | 0.0828 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0183 | 0.1048 | 0.1044 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0074 | 0.0374 | 0.9977 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0031 | 0.0062 |
Schistosoma mansoni | rab6-interacting | 0.0041 | 0.0169 | 0.039 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 2 nM | In vitro inhibition of rat liver HMG-CoA reductase | ChEMBL. | 2296036 |
IC50 (binding) | = 7.5 nM | Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]-acetate into cholesterol. | ChEMBL. | 2296036 |
Relative potency (binding) | = 6.67 | Relative inhibition of HMG-CoA reductase compared to Mevinolin. | ChEMBL. | 2296036 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.