Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0037 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.0128 | 0.0238 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.046 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | neuropeptide s receptor | 0.0614 | 0.7314 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | G-protein coupled receptor | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0734 | 0.6417 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.033 | 0.3856 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0734 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0165 | 0.184 | 0.1827 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0155 | 0.1718 | 0.8474 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus multilocularis | g-protein coupled receptor | 0.0165 | 0.184 | 0.1827 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0343 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.018 | 0.202 | 0.2008 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0165 | 0.184 | 0.1827 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.033 | 0.3856 | 1 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0052 | 0.0089 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0102 | 0.1073 | 0.1448 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0112 | 0.0131 |
Echinococcus granulosus | g protein coupled receptor | 0.0165 | 0.184 | 0.2499 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0155 | 0.1718 | 0.8474 |
Echinococcus granulosus | fmrfamide receptor | 0.0165 | 0.184 | 0.2499 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0.0146 | 0.0285 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.184 | 0.444 |
Echinococcus multilocularis | fmrfamide receptor | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | Dopamine receptor protein 1 | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1051 | 0.252 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | protein patched | 0.018 | 0.202 | 0.2008 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0075 | 0.0736 | 0.1265 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.184 | 0.444 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0128 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | ets-related | 0.0226 | 0.2586 | 0.6256 |
Brugia malayi | Serotonin receptor | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0052 | 0.004 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.046 | 0.0848 |
Brugia malayi | Dopamine receptor | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0614 | 0.7314 | 0.731 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | Dopamine receptor protein 2 | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | G protein-coupled receptor | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0149 | 0.0133 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0052 | 0.0089 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | somatostatin receptor | 0.0165 | 0.184 | 0.2499 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | g protein coupled receptor | 0.0165 | 0.184 | 0.1827 |
Schistosoma mansoni | biogenic amine receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0234 | 0.0401 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.01 | 0.1051 | 0.1805 |
Echinococcus multilocularis | protein dispatched 1 | 0.0186 | 0.2096 | 0.2083 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.184 | 0.444 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.004 | 0.0338 |
Schistosoma mansoni | patched 1 | 0.018 | 0.202 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.018 | 0.202 | 0.2747 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0149 | 0.0183 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0421 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | g-protein coupled receptor | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0605 | 0.1038 |
Echinococcus multilocularis | serotonin receptor | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0052 | 0.0089 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0734 | 0.1749 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.3856 | 0.6621 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0734 | 0.6417 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0165 | 0.184 | 0.2499 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0492 | 0.5824 | 0.7957 |
Brugia malayi | sulfakinin receptor protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0052 | 0.0089 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0282 | 0.3265 | 0.3255 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0016 | 0.0027 |
Brugia malayi | Fli-1 protein | 0.0226 | 0.2586 | 0.4441 |
Schistosoma mansoni | hypothetical protein | 0.0352 | 0.4124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0165 | 0.184 | 0.2499 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.046 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0165 | 0.184 | 0.3159 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.004 | 0.0338 |
Brugia malayi | larval opioid receptor | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | serotonin receptor | 0.0165 | 0.184 | 0.1827 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.0128 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | CHE-14 protein | 0.018 | 0.202 | 0.347 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0051 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0102 | 0.1073 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0128 | 0.0219 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0165 | 0.184 | 0.444 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | GnHR receptor homolog | 0.0165 | 0.184 | 0.3159 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.046 | 0.0892 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0128 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | histamine h1 receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0112 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | Protein patched homolog 1 | 0.018 | 0.202 | 0.2747 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.046 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0149 | 0.0256 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0734 | 0.1261 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0037 | 0.0021 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0016 | 0.0027 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.0128 | 0.0238 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | gabp alpha | 0.0075 | 0.0736 | 0.1754 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus multilocularis | neuropeptide s receptor | 0.0614 | 0.7314 | 0.731 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0165 | 0.184 | 0.2499 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0128 | 0.0238 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | g protein coupled receptor | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0037 | 0.0029 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus granulosus | serotonin receptor | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0112 | 0.0096 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | hypothetical protein | 0.0352 | 0.4124 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.184 | 0.444 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0421 | 0.0723 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | allatostatin A receptor | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0052 | 0.0089 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0026 | 0.0146 | 0.025 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0236 | 0.0406 |
Schistosoma mansoni | opsin-like receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | g protein coupled receptor | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | Melatonin receptor type 1A | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0343 | 0.0796 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | fli-1 protein | 0.0226 | 0.2586 | 0.4441 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0149 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0054 | 0.0093 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Brugia malayi | AKH receptor | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0037 | 0.0051 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0165 | 0.184 | 0.444 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.0128 | 0.0238 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0165 | 0.184 | 0.1827 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0128 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.033 | 0.3856 | 0.3846 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0165 | 0.184 | 0.444 |
Echinococcus multilocularis | fmrfamide receptor | 0.0165 | 0.184 | 0.1827 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0165 | 0.184 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0421 | 0.0723 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | myosin xvIII | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | somatostatin receptor | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | opsin-like receptor | 0.0165 | 0.184 | 0.444 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0128 | 0.0238 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.033 | 0.3856 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0492 | 0.5824 | 0.5817 |
Brugia malayi | Ets-domain containing protein | 0.0075 | 0.0736 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.018 | 0.202 | 0.347 |
Brugia malayi | neuropeptide F receptor | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0146 | 0.025 |
Leishmania major | cytochrome p450-like protein | 0.0026 | 0.0146 | 0.0048 |
Echinococcus multilocularis | allatostatin A receptor | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | putative neuropeptide receptor | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0128 | 0.0219 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.004 | 0.0338 |
Brugia malayi | hypothetical protein | 0.0052 | 0.046 | 0.079 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0734 | 0.6417 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | neuropeptide receptor | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | follicle stimulating hormone receptor | 0.0165 | 0.184 | 0.3159 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0734 | 0.6417 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0128 | 0.0238 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0165 | 0.184 | 0.2499 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus multilocularis | musashi | 0.0026 | 0.0149 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0128 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0734 | 0.1749 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0421 | 0.0723 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0149 | 0.0133 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0102 | 0.1073 | 0.1842 |
Brugia malayi | Ets-domain containing protein | 0.0075 | 0.0736 | 0.1265 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.184 | 0.2499 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0343 | 0.0796 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0016 | 0.0027 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0146 | 0.025 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | neuropeptide receptor | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1073 | 0.1842 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0165 | 0.184 | 0.1827 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0017 | 0.0037 | 0.5 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.033 | 0.3856 | 0.6621 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | orexin receptor type 2 | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0165 | 0.184 | 0.3159 |
Brugia malayi | hypothetical protein | 0.0492 | 0.5824 | 1 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.033 | 0.3856 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | geminin | 0.0352 | 0.4124 | 0.5629 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0128 | 1 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Onchocerca volvulus | 0.01 | 0.1051 | 0.5392 | |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0149 | 0.0256 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0149 | 0.0324 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.202 | 0.347 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0234 | 0.0401 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0165 | 0.184 | 0.1827 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | adenoreceptor | 0.0165 | 0.184 | 0.444 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus granulosus | expressed conserved protein | 0.0096 | 0.0997 | 0.1345 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | lamin | 0.0026 | 0.0149 | 0.0183 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | biogenic amine receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | lamin | 0.0026 | 0.0149 | 0.0324 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0037 | 0.0021 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.024 | 0.275 | 0.6656 |
Brugia malayi | Serotonin receptor | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | lamin | 0.0026 | 0.0149 | 0.0324 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0165 | 0.184 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.046 | 0.079 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0165 | 0.184 | 0.1827 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0165 | 0.184 | 0.1827 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.184 | 0.444 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0165 | 0.184 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0149 | 0.0256 |
Echinococcus multilocularis | sex peptide receptor | 0.0165 | 0.184 | 0.1827 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.0128 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0482 | 0.0828 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0155 | 0.1718 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0075 | 0.0736 | 0.0987 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0016 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | opsin-like receptor | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | biogenic amine receptor | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0165 | 0.184 | 0.3159 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0165 | 0.184 | 0.1827 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.046 | 0.0848 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0234 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.5824 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0734 | 0.072 |
Brugia malayi | ORL1-like opioid receptor | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.184 | 0.444 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0051 |
Echinococcus multilocularis | g protein coupled receptor | 0.0165 | 0.184 | 0.1827 |
Echinococcus multilocularis | geminin | 0.0352 | 0.4124 | 0.4115 |
Echinococcus granulosus | hypothetical protein | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0143 | 0.0246 |
Onchocerca volvulus | 0.0026 | 0.0149 | 0.0124 | |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.184 | 0.1827 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | RE15519p | 0.0165 | 0.184 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0128 | 0.0219 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0165 | 0.184 | 0.444 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0165 | 0.184 | 0.2499 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.046 | 0.0848 |
Trichomonas vaginalis | conserved hypothetical protein | 0.018 | 0.202 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.01 | 0.1051 | 0.252 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0102 | 0.1073 | 0.1059 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0165 | 0.184 | 0.3159 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.033 | 0.3856 | 1 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0155 | 0.1718 | 0.8474 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.033 | 0.3856 | 0.5261 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0037 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0037 | 0.0051 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.004 | 0.0338 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0165 | 0.184 | 0.1827 |
Echinococcus multilocularis | neuropeptide receptor | 0.0165 | 0.184 | 0.1827 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.046 | 0.5 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0075 | 0.0736 | 0.0722 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0343 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0128 | 0.0219 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0052 | 0.5 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0282 | 0.3265 | 0.4452 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0146 | 0.025 |
Brugia malayi | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.033 | 0.3856 | 0.9347 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0149 | 0.0256 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.1827 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0149 | 0.0183 |
Echinococcus granulosus | neuropeptide receptor | 0.0165 | 0.184 | 0.2499 |
Echinococcus multilocularis | expressed conserved protein | 0.0096 | 0.0997 | 0.0983 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0165 | 0.184 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.184 | 0.3159 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0165 | 0.184 | 0.2499 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0037 | 0.0051 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.0128 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.184 | 0.2499 |
Onchocerca volvulus | 0.0165 | 0.184 | 1 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0614 | 0.7314 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0165 | 0.184 | 0.2499 |
Brugia malayi | G-protein coupled receptor | 0.0165 | 0.184 | 0.3159 |
Echinococcus granulosus | sex peptide receptor | 0.0165 | 0.184 | 0.2499 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0146 | 0.025 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0052 | 0.1681 |
Onchocerca volvulus | 0.0026 | 0.0149 | 0.0124 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 4 nM | In vitro inhibition of rat liver HMG-CoA reductase | ChEMBL. | 2296036 |
IC50 (binding) | = 9.5 nM | Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]-acetate into cholesterol. | ChEMBL. | 2296036 |
Relative potency (binding) | = 5.26 | Relative inhibition of HMG-CoA reductase compared to Mevinolin. | ChEMBL. | 2296036 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.