Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.0094 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0628 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0628 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0296 | 0.466 | 0.4598 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0296 | 0.466 | 0.4649 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0296 | 0.466 | 0.4598 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0628 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0628 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0332 | 0.5231 | 0.5152 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0296 | 0.466 | 0.4598 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Brugia malayi | steroid hormone receptor | 0.0628 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0332 | 0.5231 | 0.515 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.0094 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.5231 | 0.515 |
Brugia malayi | nuclear receptor NHR-88 | 0.0296 | 0.466 | 0.457 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0628 | 1 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0296 | 0.466 | 0.457 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0628 | 1 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0014 | 0.0114 | 0.0094 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0296 | 0.466 | 0.4598 |
Brugia malayi | nuclear receptor NHR-67 | 0.0296 | 0.466 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0296 | 0.466 | 0.4598 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0628 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0628 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0628 | 1 | 1 |
Onchocerca volvulus | 0.0296 | 0.466 | 0.4204 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0628 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0296 | 0.466 | 0.4598 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.0094 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0296 | 0.466 | 0.4598 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0628 | 1 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0118 | 0.1791 | 0.1775 |
Brugia malayi | nuclear hormone receptor | 0.0628 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0628 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0296 | 0.466 | 0.4649 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0296 | 0.466 | 0.457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0628 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0296 | 0.466 | 0.457 |
Schistosoma mansoni | coup transcription factor | 0.0628 | 1 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0296 | 0.466 | 0.4649 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.0094 | 1 |
Onchocerca volvulus | 0.0628 | 1 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0056 | 0.0787 | 0.0633 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0628 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0332 | 0.5231 | 0.5222 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0296 | 0.466 | 0.4598 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0628 | 1 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0296 | 0.466 | 0.457 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0296 | 0.466 | 0.457 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0296 | 0.466 | 0.4568 |
Brugia malayi | nuclear receptor RXR | 0.0296 | 0.466 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Trichomonas vaginalis | helicase, putative | 0.0013 | 0.0094 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0628 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0332 | 0.5231 | 0.5152 |
Brugia malayi | tailless protein | 0.0296 | 0.466 | 0.457 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.5231 | 0.515 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0628 | 1 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0105 | 0.1588 | 0.5 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0296 | 0.466 | 0.457 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0628 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0628 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0628 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0628 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0628 | 1 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0013 | 0.0094 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Onchocerca volvulus | 0.0296 | 0.466 | 0.4204 | |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0332 | 0.5231 | 0.5177 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0296 | 0.466 | 0.4204 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0168 | 0.0055 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0296 | 0.466 | 0.457 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.0094 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0628 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0296 | 0.466 | 0.4598 |
Brugia malayi | nuclear receptor NHR-88 | 0.0628 | 1 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0059 | 0.0838 | 0.0733 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0628 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0332 | 0.5231 | 0.5222 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0628 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.5231 | 0.515 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0628 | 1 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0059 | 0.0838 | 0.0733 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0296 | 0.466 | 0.4649 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0628 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0628 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0296 | 0.466 | 0.4598 |
Schistosoma mansoni | nuclear receptor | 0.0296 | 0.466 | 0.4649 |
Schistosoma mansoni | nuclear hormone receptor | 0.0628 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0628 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0168 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0628 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0296 | 0.466 | 0.4649 |
Schistosoma mansoni | thyroid hormone receptor | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.5231 | 0.515 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0332 | 0.5231 | 0.5177 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0628 | 1 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0396 | 0.6269 | 0.6226 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0628 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0628 | 1 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0013 | 0.0094 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0628 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0059 | 0.0838 | 0.082 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.0094 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Brugia malayi | hypothetical protein | 0.0332 | 0.5231 | 0.5152 |
Brugia malayi | hypothetical protein | 0.0296 | 0.466 | 0.457 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0628 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0628 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Schistosoma mansoni | hypothetical protein | 0.0396 | 0.6269 | 0.6262 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0296 | 0.466 | 0.4568 |
Schistosoma mansoni | zinc finger protein | 0.0296 | 0.466 | 0.4649 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0296 | 0.466 | 0.457 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0296 | 0.466 | 0.4568 |
Echinococcus granulosus | dnaJ subfamily B | 0.0396 | 0.6269 | 0.6226 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0332 | 0.5231 | 0.5152 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0296 | 0.466 | 0.4204 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0628 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0059 | 0.0838 | 0.082 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.466 | 0.4568 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0332 | 0.5231 | 0.5152 |
Schistosoma mansoni | nuclear receptor | 0.0296 | 0.466 | 0.4649 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0628 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0296 | 0.466 | 0.4598 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0628 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0628 | 1 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0296 | 0.466 | 0.4568 |
Brugia malayi | nuclear hormone receptor | 0.0296 | 0.466 | 0.457 |
Schistosoma mansoni | cpg binding protein | 0.0056 | 0.0787 | 0.0769 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.5231 | 0.515 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0056 | 0.0787 | 0.0629 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0296 | 0.466 | 0.4598 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0628 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0094 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0628 | 1 | 1 |
Brugia malayi | ecdysone receptor | 0.0296 | 0.466 | 0.457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0628 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.