Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0126 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.2702 | 0.9749 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.2702 | 0.9749 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0126 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2643 | 0.9524 | 0.977 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0126 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Mean (functional) | = 0.83 | Electromyographic activity is measured as mean of the ratio of the height of the muscle action potential generated by the tenth impulse to the initial impulse in bovine thymus extracts at 10 mg | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.