Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0657 | 0.0805 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0016 | 0.001 | 0.0015 |
Loa Loa (eye worm) | thymidylate synthase | 0.0107 | 0.2768 | 0.4116 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.3278 | 0.4877 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0657 | 0.1561 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0051 | 0.1068 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0456 | 0.0666 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0051 | 0.1068 | 0.1553 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0665 | 0.0815 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 1 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0657 | 0.0943 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.1131 | 0.1123 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0484 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.671 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.1131 | 0.1674 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.671 | 0.6707 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Schistosoma mansoni | dihydrofolate reductase | 0.0044 | 0.0847 | 0.0838 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0044 | 0.0847 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0991 | 0.0982 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0156 | 0.02 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0484 | 0.0474 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0044 | 0.0847 | 0.0628 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0755 | 0.0927 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0657 | 0.0648 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0041 | 0.0769 | 0.0944 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0145 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0657 | 0.0966 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0657 | 0.1561 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0057 | 0.1261 | 0.1252 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0665 | 0.1581 |
Echinococcus granulosus | RUN | 0.0021 | 0.0145 | 0.0135 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0282 | 0.805 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0657 | 0.0805 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0261 | 0.0587 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.3278 | 0.4877 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0657 | 0.0943 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.03 | 0.0291 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0657 | 0.0648 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0484 | 0.0474 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0021 | 0.0145 | 0.0303 |
Brugia malayi | polk-prov protein | 0.0031 | 0.0456 | 0.068 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.2555 | 0.3807 |
Schistosoma mansoni | lipoxygenase | 0.0021 | 0.0145 | 0.0135 |
Schistosoma mansoni | lipoxygenase | 0.0057 | 0.1261 | 0.1252 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0022 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0657 | 0.0966 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0261 | 0.0587 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0991 | 0.1477 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0044 | 0.0847 | 0.0838 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0012 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0145 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0657 | 0.0966 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0755 | 0.0324 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0657 | 0.0943 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0138 | 0.369 | 1 |
Onchocerca volvulus | 0.0049 | 0.0991 | 0.3225 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0657 | 0.1561 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0657 | 0.0979 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0041 | 0.0769 | 0.1836 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0657 | 0.0943 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0657 | 0.0648 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.03 | 0.0291 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0991 | 0.0982 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0657 | 0.1561 |
Schistosoma mansoni | lamin | 0.0053 | 0.1131 | 0.1123 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0456 | 0.1068 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0261 | 0.0587 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0033 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0145 | 0.0202 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0261 | 0.0587 |
Brugia malayi | Dihydrofolate reductase | 0.0044 | 0.0847 | 0.1263 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0041 | 0.0769 | 0.1836 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0151 | 0.409 | 1 |
Echinococcus multilocularis | lamin | 0.0053 | 0.1131 | 0.1123 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1596 | 0.2368 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.3278 | 0.4885 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0657 | 0.0966 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0151 | 0.409 | 1 |
Onchocerca volvulus | 0.0037 | 0.0657 | 0.1952 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0145 | 0.0135 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0156 | 0.0331 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0138 | 0.369 | 0.5447 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0657 | 0.1561 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0028 | 0.0386 | 0.0575 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0136 | 0.3634 | 0.3628 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0145 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0657 | 0.0966 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0657 | 0.0943 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2555 | 0.3798 |
Echinococcus granulosus | dihydrofolate reductase | 0.0044 | 0.0847 | 0.0838 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0484 | 0.0707 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 1 | 1 |
Echinococcus multilocularis | RUN | 0.0021 | 0.0145 | 0.0135 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.1131 | 0.1686 |
Onchocerca volvulus | 0.0107 | 0.2768 | 1 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0755 | 0.0927 |
Trypanosoma brucei | unspecified product | 0.0034 | 0.0558 | 0.1317 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0484 | 0.0474 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0145 | 0.0135 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0484 | 0.0721 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0261 | 0.0587 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0041 | 0.0769 | 0.0944 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.1078 | 0.1594 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.1131 | 0.1123 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0484 | 0.0474 |
Brugia malayi | thymidylate synthase | 0.0107 | 0.2768 | 0.4124 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0041 | 0.0769 | 0.076 |
Echinococcus multilocularis | thymidylate synthase | 0.0107 | 0.2768 | 0.276 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0044 | 0.0847 | 0.0628 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0151 | 0.409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0657 | 0.0966 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.1078 | 0.1069 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.1078 | 0.1069 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0484 | 0.0474 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0021 | 0.0145 | 0.0303 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0041 | 0.0769 | 0.1836 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0107 | 0.2768 | 0.276 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0151 | 0.409 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0261 | 0.0587 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0033 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0657 | 0.0966 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0657 | 0.0943 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.1131 | 0.1123 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Brugia malayi | Doublecortin family protein | 0.0021 | 0.0145 | 0.0216 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0151 | 0.409 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0755 | 0.0324 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0657 | 0.0943 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0261 | 0.0374 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0484 | 0.0474 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.1078 | 0.1069 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0261 | 0.0388 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0145 | 0.0135 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.014 | 0.3753 | 0.5593 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0657 | 0.0966 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0657 | 0.0805 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0261 | 0.0587 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0151 | 0.409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0145 | 0.0202 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0657 | 0.0979 |
Onchocerca volvulus | 0.0053 | 0.1131 | 0.3761 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0261 | 0.0587 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.0386 | 0.0561 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0156 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0271 | 0.039 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0282 | 0.805 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0484 | 0.0474 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0657 | 0.0805 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0755 | 0.0746 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.671 | 0.6707 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0271 | 0.039 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0044 | 0.0847 | 0.1226 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1102 | 0.163 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0145 | 0.0135 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Echinococcus multilocularis | musashi | 0.0053 | 0.1131 | 0.1123 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0484 | 0.0474 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0657 | 0.0805 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0755 | 0.0746 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.1131 | 0.1674 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.1078 | 0.1069 |
Brugia malayi | guanine nucleotide-binding protein alpha-7 subunit, putative | 0.0016 | 0.001 | 0.0015 |
Onchocerca volvulus | 0.0037 | 0.0657 | 0.1952 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.1078 | 0.1069 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0484 | 0.0474 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0044 | 0.0847 | 0.125 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0018 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0107 | 0.2768 | 0.4078 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.014 | 0.3753 | 0.3747 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0145 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.03 | 0.0434 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.1131 | 0.1123 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0657 | 0.0943 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0034 | 0.0558 | 0.1317 |
Schistosoma mansoni | lamin | 0.0053 | 0.1131 | 0.1123 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.2555 | 0.3807 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0012 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.1078 | 0.1606 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0484 | 0.0721 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.1131 | 0.1686 |
Loa Loa (eye worm) | acetyltransferase | 0.014 | 0.3753 | 0.5587 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.1078 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1131 | 0.1674 |
Brugia malayi | hypothetical protein | 0.0238 | 0.671 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0484 | 0.0474 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0456 | 0.1068 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0145 | 0.0135 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0657 | 0.1561 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.2555 | 0.3798 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0145 | 0.0216 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0012 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0145 | 0.0135 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0657 | 0.0943 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0145 | 0.0135 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0156 | 0.0331 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.1078 | 0.1069 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0665 | 0.0644 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0657 | 0.0805 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0657 | 0.0943 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0107 | 0.2768 | 0.6959 |
Brugia malayi | dihydrofolate reductase family protein | 0.0044 | 0.0847 | 0.1263 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0657 | 0.0648 |
Onchocerca volvulus | 0.0037 | 0.0657 | 0.1952 | |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.1596 | 0.1588 |
Echinococcus granulosus | thymidylate synthase | 0.0107 | 0.2768 | 0.276 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0057 | 0.1261 | 0.1252 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0145 | 0.0216 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.1596 | 0.2379 |
Mycobacterium ulcerans | thymidylate synthase | 0.0107 | 0.2768 | 0.6959 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0022 | 0.0012 |
Brugia malayi | hypothetical protein | 0.0051 | 0.1068 | 0.1591 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0138 | 0.369 | 1 |
Echinococcus granulosus | lamin | 0.0053 | 0.1131 | 0.1123 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Echinococcus multilocularis | geminin | 0.0347 | 1 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0657 | 0.0979 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0051 | 0.1068 | 0.1316 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.014 | 0.3753 | 0.3747 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.805 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0755 | 0.1803 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0755 | 0.1803 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0755 | 0.1803 |
Onchocerca volvulus | 0.0053 | 0.1131 | 0.3761 | |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0145 | 0.0135 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0657 | 0.0979 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0239 | 0.6755 | 1 |
Brugia malayi | GTP-binding regulatory protein alpha chain - starfish, putative | 0.0016 | 0.001 | 0.0015 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
C175 (functional) | = 0.006 uM | Concentration needed to elicit a 75% increase beyond control in coronary flow in ''Langendorff'', guinea pig heart (in vitro) | ChEMBL. | 3346879 |
Change (functional) | = -23 % | Inhibition of [Ca2+] influx in response to a stimulus of norepinephrine (NE, 10 uM) | ChEMBL. | 3346879 |
Change (functional) | = -21 % | Inhibition of [Ca2+] influx in response to a stimulus of KCL (60 uM) | ChEMBL. | 3346879 |
Change (functional) | = -20 % | In vitro inhibition of development of isometric tension, in response to KCl (60 uM) in rabbit aorta | ChEMBL. | 3346879 |
Change (functional) | = -5 % | In vitro inhibition of development of isometric tension, in response to norepinephrine (NE, 10 uM) in rabbit aorta | ChEMBL. | 3346879 |
Control (functional) | = 115 % | Concentration needed to achieve a 75% increase in coronary blood flow in 'Langendorff', guinea pig heart (in vitro negative inotropic activity) | ChEMBL. | 3346879 |
Max fall in blood pressure (functional) | = 43 mmHg | Ability to lower blood pressure in the spontaneously hypertensive rat (SHR) at 3 mg/kg (p.o.) | ChEMBL. | 3346879 |
P (Ei) (functional) | = 0.205 | Concentration needed to achieve a 75% increase in coronary blood flow in 'Langendorff', guinea pig heart (in vitro Negative inotropic potency) | ChEMBL. | 3346879 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.