Detailed information for compound 273327

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 805.325 | Formula: C38H49ClN12O6
  • H donors: 10 H acceptors: 7 LogP: 0.8 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N)Cc1c[nH]c2c1cccc2)CCCN=C(N)N)Cc1ccc(cc1)Cl)Cc1c[nH]cn1
  • InChi: 1S/C38H49ClN12O6/c1-2-6-33(53)48-31(17-25-19-43-21-47-25)37(57)50-29(15-22-10-12-24(39)13-11-22)36(56)49-28(9-5-14-44-38(41)42)35(55)51-30(34(54)46-20-32(40)52)16-23-18-45-27-8-4-3-7-26(23)27/h3-4,7-8,10-13,18-19,21,28-31,45H,2,5-6,9,14-17,20H2,1H3,(H2,40,52)(H,43,47)(H,46,54)(H,48,53)(H,49,56)(H,50,57)(H,51,55)(H4,41,42,44)/t28-,29-,30-,31-/m0/s1
  • InChiKey: PGJYWMVUWDKZMU-ORYMTKCHSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Starlite/ChEMBL References
Homo sapiens melanocortin 4 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Theileria parva tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta-tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-2A chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis beta-catenin-like repeat protein Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium berghei tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-4 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin, beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi beta tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi beta-tubulin, identical Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-7 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin alpha chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-4 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta-1 tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0067 0.0206 0.0208
Trichomonas vaginalis apoptosis inducing factor, putative 0.0176 0.0734 0.1845
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.015 0.0609 0.1282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0236 0.0593
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0127 0.0381
Schistosoma mansoni hypothetical protein 0.0029 0.0022 0.0022
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.0337 0.0341
Mycobacterium ulcerans dehydrogenase 0.0176 0.0734 0.234
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0039 0.0038
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0032 0.0116
Leishmania major cytochrome p450-like protein 0.0043 0.0089 0.0089
Plasmodium falciparum glutathione reductase 0.0987 0.4644 1
Echinococcus multilocularis voltage dependent calcium channel 0.0135 0.0533 0.0539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0103 0.0258
Plasmodium falciparum thioredoxin reductase 0.0664 0.3086 0.6645
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0037 0.0064 0.0064
Echinococcus granulosus tubulin beta 4A class IVa 0.0027 0.0016 0.0016
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Schistosoma mansoni neuropeptide receptor 0.0206 0.0879 0.0889
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0176 0.0734 0.234
Loa Loa (eye worm) hypothetical protein 0.0079 0.0263 0.0534
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0536 0.0996
Loa Loa (eye worm) doublecortin family protein 0.0079 0.0263 0.0534
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.013 0.0511 0.0511
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0176 0.0734 0.2676
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0057 0.0143
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0176 0.0734 0.1489
Plasmodium vivax thioredoxin reductase, putative 0.0987 0.4644 1
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0094 0.0189
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.008 0.0271 0.055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0007 0.0007
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.0229 0.0231
Brugia malayi beta-tubulin, identical 0.0027 0.0016 0.0029
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0043 0.0089 0.0166
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0715 0.3332 0.337
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0059 0.0148
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0206 0.0879 0.0889
Schistosoma mansoni neuropeptide f receptor 76f 0.0206 0.0879 0.0889
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0176 0.0734 0.1845
Echinococcus granulosus GPCR family 2 0.0032 0.0038 0.0039
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0064 0.0138
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0078 0.0079
Echinococcus granulosus mitogen activated protein kinase 0.0153 0.0623 0.063
Toxoplasma gondii DNA topoisomerase 2, putative 0.0137 0.0547 0.1177
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0059 0.0148
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0037 0.0064 0.0065
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0089 0.0159
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0029 0.0072
Loa Loa (eye worm) hypothetical protein 0.0032 0.0038 0.0077
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0176 0.0734 0.1552
Schistosoma mansoni biogenic amine (5HT) receptor 0.1315 0.6224 0.6294
Loa Loa (eye worm) hypothetical protein 0.0074 0.024 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0273 0.0687
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.027 0.0677
Treponema pallidum oxidoreductase 0.0176 0.0734 0.2312
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0089 0.024
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0089 0.009
Echinococcus multilocularis epidermal growth factor receptor 0.0081 0.0274 0.0277
Trypanosoma brucei protein kinase, putative 0.0153 0.0623 0.0623
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0045 0.0103 0.0102
Echinococcus multilocularis GPCR, family 2 0.0032 0.0038 0.0039
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Brugia malayi hypothetical protein 0.0711 0.3313 0.616
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0135 0.0536 0.0541
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0043 0.0089 0.009
Echinococcus multilocularis somatostatin receptor 0.0206 0.0879 0.0889
Schistosoma mansoni hypothetical protein 0.0068 0.0212 0.0214
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0432 0.1355
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0089 0.0159
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0061 0.018 0.0182
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0068 0.017
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0022 0.0045
Echinococcus granulosus neuropeptide Y receptor 0.0206 0.0879 0.0889
Onchocerca volvulus 0.0082 0.0278 0.0836
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0068 0.017
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0206 0.0879 0.0889
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.008 0.027 0.0582
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0027 0.0016 0.0015
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0849 0.3977 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0068 0.0247
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0047 0.0047
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0182 0.076 0.0768
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0476 0.0481
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0153 0.0623 0.0623
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0026 0.0007 0.0007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0206 0.0879 0.0889
Echinococcus granulosus tm gpcr rhodopsin 0.0715 0.3332 0.337
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0579
Brugia malayi olfactory channel protein osm-9 0.0043 0.0091 0.0169
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0089 0.024
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0047 0.0047
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0064 0.013
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0061 0.018 0.0364
Schistosoma mansoni hypothetical protein 0.0043 0.0089 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.003 0.0027 0.0024
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0176 0.0734 0.158
Loa Loa (eye worm) hypothetical protein 0.0048 0.0114 0.0232
Brugia malayi Doublecortin family protein 0.0079 0.0263 0.049
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0078 0.0079
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0119 0.0458 0.1151
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0061 0.018 0.0182
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0301 0.056
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Onchocerca volvulus 0.0206 0.0879 0.2643
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0232 0.0234
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0076 0.0077
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Loa Loa (eye worm) hypothetical protein 0.0036 0.0059 0.0119
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0043 0.0089 0.0089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1571 0.7461 0.7461
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0078 0.0079
Treponema pallidum quinoline 2-oxidoreductase 0.0135 0.0534 0.1658
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0089 0.009
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0022 0.0048
Onchocerca volvulus 0.0081 0.0275 0.0827
Echinococcus granulosus glutamate synthase 0.0176 0.0734 0.0742
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Loa Loa (eye worm) tubulin beta-1 chain 0.0027 0.0016 0.0032
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0037 0.0064 0.0233
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0076 0.0077
Schistosoma mansoni jun-related protein 0.0067 0.0208 0.021
Echinococcus granulosus Adrenodoxin mitochondrial 0.0027 0.0016 0.0016
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0562 0.2595 0.8402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0007 0.0018
Echinococcus multilocularis lamin dm0 0.0081 0.0275 0.0278
Echinococcus granulosus tyrosine protein kinase Src42A 0.0067 0.0206 0.0208
Loa Loa (eye worm) phosphatidylinositol 3 0.0135 0.0536 0.1087
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0089 0.0137
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0176 0.0734 0.1845
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0047 0.0094
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0153 0.0623 0.1264
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0664 0.3086 0.3086
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0432 0.1085
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0089 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0089 0.0159
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0323 0.0326
Loa Loa (eye worm) neuropeptide F receptor 0.0206 0.0879 0.1783
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0059 0.0142
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0089 0.0159
Echinococcus granulosus tm gpcr rhodopsin 0.0206 0.0879 0.0889
Echinococcus multilocularis tyrosine protein kinase Srms 0.007 0.022 0.0223
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0176 0.0734 0.0742
Echinococcus multilocularis conserved hypothetical protein 0.0043 0.0089 0.009
Onchocerca volvulus 0.0079 0.0263 0.0792
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.045 0.0913
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0488 0.2236 0.4158
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0059 0.0058
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0013 0.0013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0059 0.0109
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0089 0.0089
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0078 0.0079
Brugia malayi follicle stimulating hormone receptor 0.0672 0.3124 0.5809
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0068 0.0126
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0007 0.0007
Echinococcus granulosus transient receptor potential gamma protein 0.0043 0.0089 0.009
Echinococcus granulosus ryanodine receptor 44f 0.0043 0.009 0.0091
Echinococcus multilocularis sodium leak channel non selective protein 0.0043 0.0089 0.009
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1315 0.6224 0.6294
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0322 0.1437 0.1453
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0278 0.1225 0.2612
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.0027 0.0036
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0093 0.0332 0.0998
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0664 0.3086 0.3086
Schistosoma mansoni inositol monophosphatase 0.0036 0.0059 0.006
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0068 0.0212 0.0214
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0059 0.0059
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0278 0.0517
Echinococcus multilocularis g protein coupled receptor 0.0206 0.0879 0.0889
Echinococcus multilocularis g protein coupled receptor 0.0206 0.0879 0.0889
Loa Loa (eye worm) G-protein coupled receptor 0.0206 0.0879 0.1783
Schistosoma mansoni tyrosine kinase 0.0081 0.0274 0.0277
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0073 0.0074
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0007 0.0007
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0051 0.0052
Toxoplasma gondii beta tubulin 0.0027 0.0016 0.0034
Echinococcus granulosus nmda type glutamate receptor 0.01 0.0366 0.037
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.0864 0.2598
Echinococcus granulosus calcium activated potassium channel 0.0044 0.0096 0.0097
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0061 0.018 0.0182
Loa Loa (eye worm) glutathione reductase 0.0987 0.4644 0.9424
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0057 0.0143
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Echinococcus granulosus neuropeptide receptor 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.0109 0.0409 0.0829
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0078 0.0079
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0176 0.0734 0.0734
Schistosoma mansoni ATP-binding cassette transporter 0.016 0.0653 0.0661
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0078 0.0146
Toxoplasma gondii hypothetical protein 0.0083 0.0285 0.0614
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0024 0.006
Loa Loa (eye worm) hypothetical protein 0.1046 0.4928 1
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0212 0.0908 0.2729
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0246 0.0248
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0022 0.0048
Echinococcus granulosus RUN 0.0079 0.0263 0.0266
Echinococcus multilocularis conserved hypothetical protein 0.1399 0.6632 0.6706
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0078 0.0146
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0987 0.4644 1
Schistosoma mansoni hypothetical protein 0.0032 0.0038 0.0039
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0402 0.1011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0078 0.0079
Brugia malayi hypothetical protein 0.0117 0.045 0.0837
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.008 0.027 0.083
Loa Loa (eye worm) blistered cuticle protein 3 0.0143 0.0571 0.1159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.044 0.1107
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0664 0.3086 0.312
Schistosoma mansoni hypothetical protein 0.0206 0.0879 0.0889
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0089 0.009
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0137 0.0547 0.0553
Echinococcus multilocularis glutamate receptor 2 0.0159 0.0652 0.0659
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0037 0.0064 0.0119
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0013 0.0013
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0509 0.0514
Plasmodium vivax DNA gyrase subunit A, putative 0.003 0.0027 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0103 0.0258
Trichomonas vaginalis DNA topoisomerase II, putative 0.0137 0.0547 0.1374
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0059 0.0059
Plasmodium falciparum ferrodoxin reductase-like protein 0.0176 0.0734 0.158
Loa Loa (eye worm) hypothetical protein 0.0101 0.0372 0.0754
Chlamydia trachomatis DNA gyrase subunit B 0.0063 0.0189 0.0566
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0135 0.0536 0.0535
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0043 0.0089 0.009
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0038 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0409 0.0413
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0135 0.0536 0.0535
Echinococcus granulosus sodium leak channel non selective protein 0.0043 0.0089 0.009
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0806 0.3771 0.7012
Trichomonas vaginalis glucosylceramidase, putative 0.0507 0.2327 0.5852
Mycobacterium ulcerans monoxygenase 0.0176 0.0734 0.234
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0078 0.0146
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0432 0.0876
Giardia lamblia NADH oxidase lateral transfer candidate 0.0664 0.3086 1
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0229 0.0231
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0614
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0432 0.0432
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0047 0.01
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0579
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0039 0.0038
Echinococcus multilocularis nmda type glutamate receptor 0.01 0.0366 0.037
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0176 0.0734 0.0742
Brugia malayi Heterochromatin protein 1 0.008 0.0272 0.0505
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0043 0.0089 0.0166
Loa Loa (eye worm) hypothetical protein 0.0806 0.3771 0.7652
Schistosoma mansoni adrenodoxin 0.0027 0.0016 0.0016
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0059 0.0215
Plasmodium falciparum phd finger protein, putative 0.0029 0.0022 0.0048
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0078 0.0079
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0016 0.0039
Giardia lamblia Beta tubulin 0.0027 0.0016 0.0051
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0068 0.0212 0.0214
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0766 0.3577 0.7694
Brugia malayi Bromodomain containing protein 0.0031 0.0034 0.0063
Loa Loa (eye worm) hypothetical protein 0.0077 0.0253 0.0514
Schistosoma mansoni polycystin 1-related 0.0079 0.0263 0.0266
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0182 0.076 0.0768
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0093 0.0332 0.0998
Onchocerca volvulus 0.0206 0.0879 0.2643
Trichomonas vaginalis tubulin, putative 0.0027 0.0016 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0623 0.1566
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0043 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0057 0.0143
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0216 0.0653
Mycobacterium ulcerans epimerase 0.004 0.0075 0.0193
Schistosoma mansoni amine GPCR 0.0206 0.0879 0.0889
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0043 0.0089 0.0166
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0182 0.076 0.0768
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0664 0.3086 0.312
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0176 0.0734 0.234
Echinococcus multilocularis thioredoxin glutathione reductase 0.0987 0.4644 0.4696
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0176 0.0734 0.0734
Giardia lamblia DNA topoisomerase II 0.013 0.0512 0.1659
Loa Loa (eye worm) TOPoisomerase family member 0.0137 0.0547 0.1109
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0176 0.0734 0.2676
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Plasmodium vivax amine transporter, putative 0.0083 0.0285 0.0614
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.049 0.2248 0.2274
Echinococcus granulosus tyrosine protein kinase Src64B 0.0077 0.0256 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0273 0.0687
Schistosoma mansoni adenoreceptor 0.0206 0.0879 0.0889
Brugia malayi intermediate filament protein 0.0081 0.0275 0.0511
Schistosoma mansoni voltage-gated cation channel 0.0135 0.0533 0.0539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0078 0.0159
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0089 0.024
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0275 0.0558
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni ryanodine receptor related 0.0043 0.009 0.009
Brugia malayi Transient-receptor-potential like protein 0.0043 0.0089 0.0166
Trichomonas vaginalis glucosylceramidase, putative 0.0507 0.2327 0.5852
Schistosoma mansoni coup transcription factor 0.004 0.0078 0.0079
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0016 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0236 0.0593
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0089 0.009
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0093 0.0332 0.0998
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0402 0.1011
Loa Loa (eye worm) hypothetical protein 0.0613 0.2842 0.5766
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0032 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0089 0.0159
Echinococcus granulosus peregrin 0.0031 0.0034 0.0035
Echinococcus granulosus tyrosine protein kinase Fyn 0.0077 0.0256 0.0259
Trypanosoma cruzi adrenodoxin precursor, putative 0.0027 0.0016 0.0015
Echinococcus granulosus neuropeptide receptor 0.0206 0.0879 0.0889
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0026 0.0007 0.0026
Loa Loa (eye worm) ryanodine receptor 0.0043 0.0089 0.0181
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0176 0.0734 0.0742
Brugia malayi voltage-dependent calcium channel 0.0043 0.0089 0.0166
Echinococcus granulosus FTZ F1 alpha 0.004 0.0078 0.0079
Echinococcus multilocularis tubulin beta 1 chain 0.0027 0.0016 0.0016
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0275 0.0558
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0022 0.0045
Loa Loa (eye worm) tubulin beta-2A chain 0.0027 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0154 0.0311
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0027 0.0016 0.0029
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0061 0.018 0.0182
Loa Loa (eye worm) hypothetical protein 0.0132 0.0518 0.1052
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.015 0.0609 0.1312
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0432 0.1085
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0176 0.0734 0.0734
Echinococcus multilocularis neuropeptides capa receptor 0.0206 0.0879 0.0889
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0078 0.0079
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0275 0.0511
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0061 0.018 0.0182
Loa Loa (eye worm) solute carrier family 6 member 4 0.049 0.2248 0.4563
Trypanosoma brucei DNA topoisomerase ii 0.0154 0.0628 0.0628
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0664 0.3086 0.6634
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0176 0.0734 0.234
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0083 0.0285 0.0288
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0091 0.0092
Echinococcus granulosus thioredoxin glutathione reductase 0.0987 0.4644 0.4696
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0531
Mycobacterium ulcerans NADH dehydrogenase 0.0176 0.0734 0.234
Giardia lamblia Fructose-bisphosphate aldolase 0.0593 0.2742 0.8886
Trypanosoma brucei DNA topoisomerase II beta, putative 0.013 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0273 0.0687
Schistosoma mansoni cpg binding protein 0.0062 0.0181 0.0183
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0127 0.0318
Echinococcus multilocularis transient receptor potential gamma protein 0.0043 0.0089 0.009
Echinococcus granulosus neuropeptide Y receptor 0.0206 0.0879 0.0889
Brugia malayi Cytochrome P450 family protein 0.0069 0.0216 0.0402
Treponema pallidum sodium- and chloride- dependent transporter 0.049 0.2248 0.7263
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis serotonin transporter 0.049 0.2248 0.2274
Brugia malayi Glutamate receptor 1 precursor 0.0159 0.0652 0.1211
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.0091 0.0092
Plasmodium vivax glutathione reductase, putative 0.0987 0.4644 1
Echinococcus granulosus tyrosine kinase 0.0025 0.0006 0.0006
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0027 0.0016 0.0016
Echinococcus granulosus voltage dependent calcium channel 0.006 0.0173 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0536 0.1346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0307 0.0772
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Echinococcus granulosus shaker cognate 0.0043 0.0089 0.009
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0061 0.018 0.0182
Brugia malayi Bromodomain containing protein 0.0082 0.0277 0.0516
Echinococcus multilocularis orexin receptor type 2 0.0206 0.0879 0.0889
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0077 0.0256 0.0259
Onchocerca volvulus 0.0083 0.0285 0.0858
Schistosoma mansoni voltage-gated ion channel 0.0043 0.0089 0.009
Echinococcus granulosus glutamate receptor 2 0.0182 0.076 0.0768
Echinococcus multilocularis sex peptide receptor 0.0206 0.0879 0.0889
Echinococcus multilocularis two pore calcium channel protein 1 0.0043 0.0089 0.009
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0337 0.034
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0039 0.0083
Loa Loa (eye worm) BEN-1 protein 0.0027 0.0016 0.0032
Echinococcus multilocularis sodium channel protein 0.0464 0.2123 0.2147
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0176 0.0734 0.0742
Loa Loa (eye worm) hypothetical protein 0.0117 0.0448 0.091
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0206 0.0879 0.0889
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1782 0.8479 0.8479
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Onchocerca volvulus 0.049 0.2248 0.676
Loa Loa (eye worm) CHromoDomain protein family member 0.0028 0.0021 0.0042
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0176 0.0734 0.196
Loa Loa (eye worm) TYRA-2 protein 0.0206 0.0879 0.1783
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0176 0.0734 0.234
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0664 0.3086 1
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0078 0.0079
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0089 0.024
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0509 0.1032
Toxoplasma gondii ferodoxin FD 0.0027 0.0016 0.0033
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0078 0.0146
Onchocerca volvulus 0.0206 0.0879 0.2643
Giardia lamblia Beta tubulin 0.0027 0.0016 0.0051
Trichomonas vaginalis aldehyde oxidase, putative 0.0849 0.3977 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0664 0.3086 0.312
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0135 0.0533 0.0539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0235 0.0591
Leishmania major trypanothione reductase 0.0987 0.4644 0.4644
Echinococcus granulosus peptide allatostatin:somatostatin 0.0206 0.0879 0.0889
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0766 0.3577 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Mycobacterium ulcerans hypothetical protein 0.004 0.0075 0.0193
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.0089 0.009
Echinococcus multilocularis neuropeptide receptor A26 0.1109 0.5231 0.529
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.025 0.0249
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0098 0.0355 0.0355
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0078 0.0079
Echinococcus multilocularis chromobox protein 1 0.008 0.0272 0.0275
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0176 0.0734 0.158
Trichomonas vaginalis Ferredoxin 1 0.0027 0.0016 0.0039
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.015 0.0609 0.1133
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0039 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0141 0.0353
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0078 0.0079
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0077 0.0256 0.0259
Loa Loa (eye worm) hypothetical protein 0.049 0.2248 0.4563
Toxoplasma gondii thioredoxin reductase 0.0987 0.4644 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0432 0.1324
Schistosoma mansoni glutamate receptor NMDA 0.0259 0.1133 0.1146
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0206 0.0879 0.0889
Brugia malayi glutathione reductase 0.0987 0.4644 0.8635
Loa Loa (eye worm) hypothetical protein 0.049 0.2248 0.4563
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0206 0.0879 0.1634
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0059 0.0059
Echinococcus granulosus fmrfamide receptor 0.0206 0.0879 0.0889
Echinococcus granulosus sodium and chloride dependent glycine 0.0083 0.0285 0.0289
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0614
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0057 0.0143
Brugia malayi Furin-like cysteine rich region family protein 0.0149 0.0601 0.1118
Brugia malayi Sodium:neurotransmitter symporter family protein 0.049 0.2248 0.4181
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0176 0.0734 0.1552
Onchocerca volvulus 0.0079 0.0263 0.0792
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0176 0.0734 0.2676
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0045 0.0103 0.0102
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0153 0.0623 0.0623
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Schistosoma mansoni transient receptor potential channel 0.0043 0.0091 0.0092
Plasmodium vivax ataxin-2 like protein, putative 0.0076 0.025 0.0537
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0176 0.0734 0.158
Loa Loa (eye worm) hypothetical protein 0.0149 0.0601 0.122
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0176 0.0734 0.0742
Schistosoma mansoni hypothetical protein 0.0032 0.0038 0.0039
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0078 0.0079
Plasmodium vivax ferrodoxin reductase, putative 0.0176 0.0734 0.158
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0176 0.0734 0.1552
Schistosoma mansoni 60S ribosomal protein L21 0.0053 0.0139 0.014
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0068 0.0069
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0078 0.0079
Echinococcus multilocularis microtubule associated protein 2 0.2075 0.9889 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0083 0.0285 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0089 0.009
Giardia lamblia [2Fe-2S] ferredoxin 0.0027 0.0016 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0089 0.0159
Brugia malayi 6-phosphofructokinase 0.0114 0.0432 0.0803
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0039 0.0083
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0301 0.0305
Loa Loa (eye worm) tubulin beta chain 0.0027 0.0016 0.0032
Echinococcus multilocularis Polycystic kidney disease protein 0.0079 0.0263 0.0266
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0094 0.0337 0.0341
Echinococcus multilocularis voltage dependent calcium channel 0.0135 0.0533 0.0539
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0089 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0078 0.0159
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.008 0.027 0.0797
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0059 0.006
Echinococcus multilocularis calcium activated potassium channel 0.0044 0.0096 0.0097
Echinococcus multilocularis neuropeptide receptor 0.0206 0.0879 0.0889
Schistosoma mansoni cpg binding protein 0.0062 0.0181 0.0183
Echinococcus granulosus voltage gated potassium channel 0.0043 0.0089 0.009
Echinococcus granulosus serotonin transporter 0.049 0.2248 0.2274
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0089 0.0089
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0027 0.0016 0.0033
Trypanosoma cruzi beta tubulin, putative 0.0027 0.0016 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0139 0.014
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0077 0.0256 0.0259
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0089 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0032 0.008
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0089 0.009
Schistosoma mansoni voltage-dependent calcium channel 0.0043 0.0089 0.009
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0039 0.0038
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0176 0.0734 0.1845
Loa Loa (eye worm) hypothetical protein 0.0087 0.0301 0.0611
Trichomonas vaginalis Ferredoxin 7 0.0027 0.0016 0.0039
Plasmodium falciparum DNA gyrase subunit A 0.003 0.0027 0.0057
Onchocerca volvulus 0.0117 0.0448 0.1348
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0664 0.3086 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0121 0.0245
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0043 0.0089 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0235 0.0591
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1782 0.8479 0.8479
Schistosoma mansoni amine GPCR 0.0206 0.0879 0.0889
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0043 0.0089 0.0089
Trichomonas vaginalis mercuric reductase, putative 0.0664 0.3086 0.7759
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0176 0.0734 0.158
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0059
Echinococcus granulosus allatostatin A receptor 0.0206 0.0879 0.0889
Echinococcus granulosus nmda type glutamate receptor 0.0183 0.0765 0.0774
Brugia malayi cation channel family protein 0.0043 0.0089 0.0166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0133
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0038 0.0071
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0013 0.0013
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0061 0.018 0.0182
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0073 0.0074
Echinococcus granulosus neuropeptides capa receptor 0.0206 0.0879 0.0889
Plasmodium falciparum thioredoxin reductase 0.0987 0.4644 1
Loa Loa (eye worm) hypothetical protein 0.015 0.0609 0.1236
Brugia malayi hypothetical protein 0.0079 0.0263 0.049
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0464 0.2123 0.2147
Schistosoma mansoni sulfide quinone reductase 0.0176 0.0734 0.0742
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0022 0.0022
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0013 0.0013
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1571 0.7461 0.7461
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.027 0.0677
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0068 0.0068
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1885 0.8977 0.9077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0057 0.0143
Loa Loa (eye worm) hypothetical protein 0.006 0.0173 0.0351
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0083 0.0285 0.0879
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0089 0.024
Leishmania major cytochrome p450-like protein 0.0069 0.0216 0.0216
Echinococcus multilocularis shaker cognate 0.0043 0.0089 0.009
Loa Loa (eye worm) voltage-gated calcium channel 0.0043 0.0089 0.0181
Schistosoma mansoni vesicular amine transporter 0.0043 0.0089 0.009
Plasmodium vivax DNA gyrase subunit B, putative 0.008 0.027 0.0582
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0089 0.009
Onchocerca volvulus 0.0083 0.0285 0.0858
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0007 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0089 0.0159
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0077 0.0256 0.0259
Entamoeba histolytica protein kinase rad3, putative 0.0026 0.0007 0.0026
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.015 0.0609 0.1608
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0176 0.0734 0.0742
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0043 0.0089 0.0166
Echinococcus granulosus lamin dm0 0.0081 0.0275 0.0278
Schistosoma mansoni neuropeptide receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis chromobox protein, putative 0.008 0.0272 0.0683
Leishmania major phosphatidylinositol 3-kinase, putative 0.0045 0.0103 0.0102
Onchocerca volvulus 0.0206 0.0879 0.2643
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0043 0.0089 0.009
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0045 0.0103 0.0104
Brugia malayi isocitrate dehydrogenase 0.0032 0.0039 0.0071
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.029 0.128 0.4119
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0176 0.0734 0.196
Echinococcus multilocularis hyperpolarization activated cyclic 0.0061 0.018 0.0182
Brugia malayi G protein-coupled receptor 0.0206 0.0879 0.1634
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0278 0.1225 0.2612
Toxoplasma gondii LsmAD domain-containing protein 0.0076 0.025 0.0537
Echinococcus multilocularis neuropeptides capa receptor 0.0206 0.0879 0.0889
Brugia malayi sulfakinin receptor protein 0.0206 0.0879 0.1634
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0089 0.0159
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0664 0.3086 0.6645
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0623 0.063
Echinococcus granulosus microtubule associated protein 2 0.2075 0.9889 1
Schistosoma mansoni disulfide oxidoreductase 0.0176 0.0734 0.0742
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0229 0.0231
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0037 0.0064 0.0064
Schistosoma mansoni glutamate receptor NMDA 0.0322 0.1437 0.1453
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0432 0.0436
Plasmodium falciparum LCCL domain-containing protein 0.0079 0.0263 0.0567
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0509 0.0508
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0039 0.0083
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0097 0.0351 0.1279
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0432 0.1085
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0206 0.0879 0.0889
Schistosoma mansoni voltage-gated potassium channel 0.016 0.0658 0.0665
Schistosoma mansoni hypothetical protein 0.0206 0.0879 0.0889
Brugia malayi hypothetical protein 0.0065 0.0197 0.0365
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0137 0.0547 0.0553
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0078 0.0146
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0206 0.0879 0.1783
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Leishmania major hypothetical protein, conserved 0.0176 0.0734 0.0734
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0064 0.0192 0.0192
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0176 0.0734 0.2378
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0068 0.022
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0037 0.0063 0.012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0282 0.0285
Mycobacterium ulcerans endonuclease IV 0.015 0.0609 0.1933
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0032 0.0069
Schistosoma mansoni hypothetical protein 0.0034 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0038 0.0039
Schistosoma mansoni nuclear hormone receptor 0.004 0.0078 0.0079
Toxoplasma gondii selenide, water dikinase 0.0176 0.0734 0.158
Schistosoma mansoni neuropeptide F-like receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0176 0.0734 0.1845
Loa Loa (eye worm) thioredoxin reductase 0.0987 0.4644 0.9424
Entamoeba histolytica DNA topoisomerase II, putative 0.0137 0.0547 0.1993
Echinococcus granulosus dnaJ subfamily B 0.0802 0.3754 0.3796
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1571 0.7461 0.7461
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Echinococcus granulosus glutamate NMDA receptor subunit 0.0322 0.1437 0.1453
Mycobacterium leprae putative cytochrome p450 0.0043 0.0089 0.0137
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0432 0.0436
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0153 0.0623 0.0623
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0032 0.0018
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0089 0.009
Echinococcus multilocularis voltage gated potassium channel 0.0043 0.0089 0.009
Echinococcus granulosus ferredoxin 0.0027 0.0016 0.0016
Schistosoma mansoni ap endonuclease 0.0038 0.0068 0.0069
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0147
Loa Loa (eye worm) hypothetical protein 0.0076 0.0249 0.0505
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0089 0.024
Giardia lamblia PHD finger protein 15 0.0029 0.0022 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.0747 0.3485 0.7072
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0323 0.0695
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0075 0.0128
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0037 0.0063 0.0103
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0029 0.0072
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0664 0.3086 0.6645
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0432 0.1106
Trypanosoma cruzi adrenodoxin precursor, putative 0.0027 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Echinococcus multilocularis lipoxygenase domain containing protein 0.0079 0.0263 0.0266
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0145 0.0583 0.1085
Echinococcus granulosus g-protein coupled receptor 0.0206 0.0879 0.0889
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0047 0.0047
Schistosoma mansoni cellular tumor antigen P53 0.0149 0.0601 0.0608
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0038 0.0039
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0427 0.1941 0.1941
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0176 0.0734 0.1845
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0176 0.0734 0.0734
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0089 0.009
Echinococcus granulosus tyrosine protein kinase HCK 0.0062 0.0184 0.0186
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Echinococcus multilocularis g protein coupled receptor 0.0206 0.0879 0.0889
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0182 0.076 0.0768
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0089 0.024
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0162 0.0665 0.2117
Echinococcus granulosus g protein coupled receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0536 0.1346
Echinococcus granulosus g protein coupled receptor 0.0206 0.0879 0.0889
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0509 0.0508
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0047 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Echinococcus multilocularis voltage gated potassium channel 0.0071 0.0229 0.0231
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0089 0.0192
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0032 0.008
Chlamydia trachomatis endonuclease IV 0.015 0.0609 0.1933
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0068 0.0171
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0176 0.0734 0.158
Schistosoma mansoni transient receptor potential channel 0.0043 0.0089 0.009
Brugia malayi Melatonin receptor type 1A 0.0206 0.0879 0.1634
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0176 0.0734 0.234
Echinococcus granulosus hyperpolarization activated cyclic 0.0061 0.018 0.0182
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0206 0.0879 0.0889
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0091 0.0092
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0176 0.0734 0.196
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0176 0.0734 0.0742
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0176 0.0734 0.0742
Leishmania major ferredoxin, 2fe-2s-like protein 0.0027 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trypanosoma brucei PAB1-binding protein , putative 0.0076 0.025 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0078 0.0146
Brugia malayi SET domain containing protein 0.0028 0.0017 0.0032
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0022 0.0067
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0064 0.013
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0432 0.1085
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0027 0.0016 0.0047
Onchocerca volvulus 0.0206 0.0879 0.2643
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0089 0.0159
Trichomonas vaginalis Ferredoxin 6 0.0027 0.0016 0.0039
Onchocerca volvulus 0.0027 0.0016 0.0047
Schistosoma mansoni hypothetical protein 0.0206 0.0879 0.0889
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Echinococcus granulosus tyrosine kinase 0.007 0.022 0.0223
Loa Loa (eye worm) voltage-gated potassium channel 0.0043 0.0089 0.0181
Trypanosoma brucei NADH dehydrogenase 0.0176 0.0734 0.0734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0236 0.0593
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0078 0.0159
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0301 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0078 0.0146
Schistosoma mansoni biogenic amine receptor 0.0206 0.0879 0.0889
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0083 0.0285 0.0531
Onchocerca volvulus 0.0029 0.0022 0.0067
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0206 0.0879 0.2643
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0078 0.0236
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0206 0.0879 0.0889
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0089 0.024
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0206 0.0879 0.0889
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0664 0.3086 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0372 0.0691
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0061 0.018 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2098 1 1
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0176 0.0734 0.234
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Schistosoma mansoni lipoxygenase 0.0409 0.1856 0.1876
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0282 0.0285
Onchocerca volvulus 0.0117 0.0448 0.1348
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0089 0.009
Loa Loa (eye worm) melatonin receptor type 1A 0.0206 0.0879 0.1783
Schistosoma mansoni opsin-like receptor 0.0206 0.0879 0.0889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0206 0.0879 0.0889
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0016 0.0015
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0064 0.0138
Brugia malayi hypothetical protein 0.0079 0.0263 0.049
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0176 0.0734 0.1845
Echinococcus granulosus tachykinin peptides receptor 99D 0.0206 0.0879 0.0889
Schistosoma mansoni DNA topoisomerase II 0.0137 0.0547 0.0553
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0083 0.0285 0.0288
Brugia malayi Dopamine receptor protein 1 0.0613 0.2842 0.5284
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0078 0.0079
Loa Loa (eye worm) inositol-1 0.0036 0.0059 0.012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2098 1 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0071 0.0229 0.0425
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0065 0.0066
Loa Loa (eye worm) TK/INSR protein kinase 0.0049 0.012 0.0244
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0032 0.0069
Brugia malayi Cytochrome P450 family protein 0.01 0.0365 0.0679
Loa Loa (eye worm) hypothetical protein 0.0176 0.0734 0.1489
Trichomonas vaginalis glutamate synthase, putative 0.0176 0.0734 0.1845
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0078 0.0079
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0089 0.009
Schistosoma mansoni hypothetical protein 0.0509 0.2341 0.2367
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0135 0.0536 0.0542
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0078 0.0079
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.0027 0.0036
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0432 0.0437
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0623 0.1566
Trichomonas vaginalis chromobox protein, putative 0.008 0.0272 0.0683
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0089 0.009
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0094 0.0174
Onchocerca volvulus 0.003 0.0029 0.0088
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0043 0.0089 0.0166
Loa Loa (eye worm) hypothetical protein 0.0069 0.0217 0.0441
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0216 0.0439
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0045 0.0103 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0032 0.008
Brugia malayi bZIP transcription factor family protein 0.0083 0.0282 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0103 0.0258
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0089 0.024
Echinococcus multilocularis tyrosine protein kinase Fyn 0.007 0.022 0.0223
Schistosoma mansoni calcium-activated potassium channel 0.0043 0.0089 0.009
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0216 0.0216
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0059 0.0059
Echinococcus multilocularis serotonin receptor 0.0573 0.2647 0.2677
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0022 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0076 0.0155
Trichomonas vaginalis Ferredoxin 2 0.0027 0.0016 0.0039
Schistosoma mansoni lamin 0.0081 0.0275 0.0278
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.004 0.0075 0.0139
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0507 0.2327 0.4327
Schistosoma mansoni biogenic amine receptor 0.0206 0.0879 0.0889
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0509 0.0508
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0089 0.024
Schistosoma mansoni loxhd1 0.0079 0.0263 0.0266
Mycobacterium ulcerans hypothetical protein 0.0138 0.0549 0.1738
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0089 0.024
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0216 0.0216
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0083 0.0285 0.0289
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0176 0.0734 0.1845
Schistosoma mansoni glutamate receptor AMPA 0.0159 0.0652 0.0659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0402 0.1011
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0206 0.0879 0.1783
Schistosoma mansoni thyroid hormone receptor 0.004 0.0078 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.015 0.0609 0.1312
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0043 0.0089 0.009
Giardia lamblia Kinase, CMGC MAPK 0.0153 0.0623 0.2018
Trypanosoma brucei hypothetical protein, conserved 0.0176 0.0734 0.0734
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0026 0.0007 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0007 0.0013
Echinococcus multilocularis lipoxygenase domain containing protein 0.0079 0.0263 0.0266
Schistosoma mansoni neuropeptide receptor 0.0206 0.0879 0.0889
Brugia malayi protein-tyrosine kinase 0.007 0.022 0.0409
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0089 0.009
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0103 0.019
Schistosoma mansoni tyrosine kinase 0.0077 0.0256 0.0259
Echinococcus multilocularis glutamate receptor NMDA 0.0078 0.0258 0.0261
Brugia malayi Serotonin receptor 0.0206 0.0879 0.1634
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0068 0.0113
Toxoplasma gondii transporter, cation channel family protein 0.0043 0.0089 0.0192
Plasmodium vivax ferredoxin, putative 0.0027 0.0016 0.0033
Schistosoma mansoni tyrosine kinase 0.0025 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0078 0.0146
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1571 0.7461 0.7461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Brugia malayi jmjC domain containing protein 0.0094 0.0337 0.0626
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0068 0.0146
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0059
Schistosoma mansoni neuropeptide receptor 0.0206 0.0879 0.0889
Chlamydia trachomatis thioredoxin reductase 0.0176 0.0734 0.234
Brugia malayi phosphofructokinase 0.0114 0.0432 0.0803
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0043 0.0089 0.009
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.003 0.0027 0.0057
Loa Loa (eye worm) cytochrome P450 family protein 0.01 0.0365 0.0741
Onchocerca volvulus 0.0073 0.0238 0.0715
Schistosoma mansoni intermediate filament proteins 0.0081 0.0275 0.0278
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0176 0.0734 0.1365
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0151
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.015 0.0609 0.1132
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0301 0.0305
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0078 0.0079
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Schistosoma mansoni hypothetical protein 0.0067 0.0208 0.021
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0154 0.0628 0.0628
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0206 0.0879 0.0889
Onchocerca volvulus Alhambra homolog 0.0029 0.0022 0.0067
Loa Loa (eye worm) hypothetical protein 0.0117 0.045 0.0913
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0089 0.0159
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0094 0.0337 0.0341
Onchocerca volvulus Neuropeptide F receptor homolog 0.0206 0.0879 0.2643
Echinococcus granulosus neuropeptide s receptor 0.1109 0.5231 0.529
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Loa Loa (eye worm) hypothetical protein 0.0573 0.2647 0.5372
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0278 0.1225 0.3348
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0135 0.0533 0.0539
Brugia malayi Bromodomain containing protein 0.004 0.0077 0.0143
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0078 0.0146
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0077 0.0256 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0078 0.0159
Onchocerca volvulus 0.0176 0.0734 0.2207
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0032 0.0069
Echinococcus granulosus histone lysine methyltransferase setb 0.0109 0.0409 0.0413
Schistosoma mansoni tyrosine kinase 0.0081 0.0274 0.0277
Toxoplasma gondii ferredoxin, putative 0.0027 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Echinococcus granulosus lamin 0.0081 0.0275 0.0278
Echinococcus multilocularis insulin receptor 0.0049 0.012 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0114 0.0434 0.0439
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0007 0.0007
Onchocerca volvulus 0.0206 0.0879 0.2643
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0409 0.0413
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0337 0.034
Echinococcus granulosus G protein coupled receptor 139 0.0206 0.0879 0.0889
Echinococcus multilocularis sodium and chloride dependent glycine 0.0083 0.0285 0.0289
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0047 0.0047
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0135 0.0536 0.0535
Echinococcus multilocularis geminin 0.0509 0.2341 0.2367
Echinococcus granulosus glutamate receptor 2 0.0114 0.0432 0.0436
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0089 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0043 0.0089 0.009
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0064 0.0161
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0162 0.0665 0.1404
Schistosoma mansoni hypothetical protein 0.0079 0.0263 0.0266
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0013
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0078 0.0079
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0153 0.0623 0.0623
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0409 0.1856 0.1876
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0043 0.0089 0.0166
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0027 0.0016 0.0015
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.045 0.0913
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0032 0.0053
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0089 0.024
Schistosoma mansoni lamin 0.0081 0.0275 0.0278
Schistosoma mansoni hypothetical protein 0.0087 0.0301 0.0305
Loa Loa (eye worm) hypothetical protein 0.0079 0.0263 0.0534
Schistosoma mansoni hypothetical protein 0.0509 0.2341 0.2367
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0032 0.0069
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0089 0.009
Trypanosoma cruzi DNA topoisomerase II, putative 0.013 0.0511 0.0511
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0032 0.008
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0068 0.0212 0.0214
Onchocerca volvulus 0.0077 0.0253 0.0762
Brugia malayi hypothetical protein 0.0049 0.012 0.0223
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Schistosoma mansoni two-pore calcium channel 0.0043 0.0089 0.009
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0089 0.0159
Echinococcus granulosus tyrosine protein kinase Src42A 0.0077 0.0256 0.0259
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0206 0.0879 0.0889
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0007 0.0015
Treponema pallidum thioredoxin reductase (trxB) 0.0176 0.0734 0.2312
Echinococcus granulosus voltage dependent calcium channel 0.0135 0.0533 0.0539
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0176 0.0734 0.0734
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0278 0.0281
Brugia malayi cation channel family protein 0.0043 0.0089 0.0166
Leishmania major NADH dehydrogenase, putative 0.0176 0.0734 0.0734
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0059 0.0059
Leishmania major hypothetical protein, unknown function 0.0043 0.0089 0.0089
Leishmania major hypothetical protein, conserved 0.0043 0.0089 0.0089
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0059
Echinococcus multilocularis mitogen activated protein kinase 0.0153 0.0623 0.063
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0301 0.0611
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0038 0.0071
Echinococcus multilocularis tyrosine protein kinase Blk 0.007 0.022 0.0223
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0089 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0076 0.025 0.0506
Echinococcus granulosus g protein coupled receptor 0.0206 0.0879 0.0889
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0078 0.0079
Loa Loa (eye worm) hypothetical protein 0.0082 0.0278 0.0564
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0061 0.018 0.0452
Schistosoma mansoni tyrosine kinase 0.0025 0.0006 0.0006
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0048 0.0048
Echinococcus multilocularis musashi 0.0081 0.0275 0.0278
Brugia malayi Protein kinase domain containing protein 0.0049 0.012 0.0223
Schistosoma mansoni cpg binding protein 0.0056 0.0156 0.0157
Loa Loa (eye worm) beta-tubulin 0.0027 0.0016 0.0032
Echinococcus granulosus serotonin receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0029 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Echinococcus granulosus glutamate receptor NMDA 0.0078 0.0258 0.0261
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0089 0.024
Loa Loa (eye worm) calcium channel 0.0135 0.0533 0.1082
Schistosoma mansoni lipoxygenase 0.0267 0.1173 0.1186
Brugia malayi jmjC domain containing protein 0.004 0.0076 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0089 0.0159
Echinococcus multilocularis neuropeptide FF receptor 2 0.0206 0.0879 0.0889
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0531
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0232 0.0234
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0027 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Echinococcus granulosus tyrosine protein kinase Blk 0.007 0.022 0.0223
Schistosoma mansoni histamine h1 receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0059 0.0148
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0176 0.0734 0.234
Brugia malayi neuropeptide F receptor 0.0206 0.0879 0.1634
Loa Loa (eye worm) hypothetical protein 0.0711 0.3313 0.6722
Brugia malayi PHD-finger family protein 0.0029 0.0025 0.0046
Brugia malayi Pre-SET motif family protein 0.0091 0.0323 0.06
Loa Loa (eye worm) TK protein kinase 0.007 0.022 0.0447
Trichomonas vaginalis Ferredoxin 4 0.0027 0.0016 0.0039
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0176 0.0734 0.196
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0039 0.0038
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0176 0.0734 0.158
Echinococcus granulosus beta tubulin 0.0027 0.0016 0.0016
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.034 0.1525 0.5561
Schistosoma mansoni survival motor neuron protein 0.0145 0.0583 0.059
Loa Loa (eye worm) glutamate receptor 2 0.0159 0.0652 0.1322
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.003 0.0027 0.0036
Echinococcus multilocularis lamin 0.0081 0.0275 0.0278
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis tyrosine kinase 0.0025 0.0006 0.0006
Echinococcus granulosus alpha 1A adrenergic receptor 0.0206 0.0879 0.0889
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0176 0.0734 0.0742
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0077 0.0256 0.0259
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2098 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0206 0.0879 0.0889
Mycobacterium leprae conserved hypothetical protein 0.004 0.0075 0.0096
Echinococcus multilocularis G-protein coupled receptor, putative 0.0206 0.0879 0.0889
Toxoplasma gondii hypothetical protein 0.0083 0.0285 0.0614
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0135 0.0533 0.0539
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0135 0.0536 0.0535
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0089 0.0159
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0246 0.0248
Loa Loa (eye worm) hypothetical protein 0.0203 0.0864 0.1754
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0061 0.018 0.0452
Trichomonas vaginalis glucosylceramidase, putative 0.0507 0.2327 0.5852
Echinococcus multilocularis peregrin 0.0031 0.0034 0.0035
Echinococcus granulosus survival motor neuron protein 1 0.0711 0.3313 0.335
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0078 0.0146
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Echinococcus multilocularis epidermal growth factor receptor 0.0149 0.0601 0.0608
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0043 0.0089 0.0166
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0372 0.0691
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0664 0.3086 1
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0067 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.005 0.0127 0.0257
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0059 0.0059
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0135 0.0533 0.0539
Brugia malayi Dopamine receptor protein 2 0.0206 0.0879 0.1634
Schistosoma mansoni tyrosine kinase 0.0078 0.026 0.0263
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0059 0.0127
Treponema pallidum fructose-bisphosphate aldolase 0.0593 0.2742 0.8876
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0037 0.0064 0.0138
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0176 0.0734 0.2676
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0672 0.3124 0.6339
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0664 0.3086 1
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0064 0.0064
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0032 0.008
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0027 0.0016 0.0016
Brugia malayi Inositol-1 0.0036 0.0059 0.011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0301 0.0304
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0078 0.0146
Leishmania major mitochondrial DNA topoisomerase II 0.0154 0.0628 0.0628
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0078 0.0146
Echinococcus granulosus epidermal growth factor receptor 0.0081 0.0274 0.0277
Schistosoma mansoni voltage-gated potassium channel 0.0061 0.018 0.0182
Echinococcus granulosus jumonji domain containing protein 0.004 0.0076 0.0077
Brugia malayi glutamate synthase 0.0176 0.0734 0.1365
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0045 0.0103 0.0102
Echinococcus multilocularis tubulin subunit beta 0.0027 0.0016 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0614
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0043 0.0089 0.009
Treponema pallidum hypothetical protein 0.0114 0.0432 0.1325
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0059 0.0189
Brugia malayi Dopamine receptor 0.0206 0.0879 0.1634
Echinococcus multilocularis hyperpolarization activated cyclic 0.0061 0.018 0.0182
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0206 0.0879 0.0889
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0059 0.0147
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.015 0.0609 0.0616
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0135 0.0536 0.1953
Brugia malayi hypothetical protein 0.0083 0.0285 0.0531
Trypanosoma cruzi NADH dehydrogenase, putative 0.0176 0.0734 0.0734
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.02 0.0203
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0089 0.024
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0043 0.0089 0.009
Echinococcus granulosus sodium channel protein 0.0427 0.1941 0.1963
Trypanosoma cruzi hypothetical protein, conserved 0.0176 0.0734 0.0734
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0301 0.0305
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0038 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0059 0.0147
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0043 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Echinococcus granulosus hyperpolarization activated cyclic 0.0061 0.018 0.0182
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0153 0.0623 0.0623
Schistosoma mansoni glutamate receptor kainate 0.0159 0.0652 0.0659
Schistosoma mansoni transient receptor potential channel 4 0.0043 0.0089 0.009
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0432 0.1574
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0029 0.0072
Brugia malayi Adenylyl cyclase protein 0.0077 0.0253 0.0471
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Onchocerca volvulus Dual oxidase homolog 0.0143 0.0571 0.1718
Brugia malayi neuropeptide F receptor 0.0206 0.0879 0.1634
Echinococcus granulosus tyrosine protein kinase Fyn 0.0077 0.0256 0.0259
Schistosoma mansoni adrenodoxin 0.0027 0.0016 0.0016
Echinococcus granulosus tumor protein p63 0.1016 0.4783 0.4837
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0047 0.01
Schistosoma mansoni glutamate synthase 0.0176 0.0734 0.0742
Schistosoma mansoni glutamate synthase 0.0176 0.0734 0.0742
Schistosoma mansoni growth hormone secretagogue receptor 0.0206 0.0879 0.0889
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0043 0.0089 0.0166
Onchocerca volvulus 0.004 0.0078 0.0236
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0206 0.0879 0.0889
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0068 0.0138
Echinococcus multilocularis sodium and chloride dependent glycine 0.0083 0.0285 0.0289
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0176 0.0734 0.0734
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0057 0.0143
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0137 0.0547 0.1016
Echinococcus multilocularis RUN 0.0079 0.0263 0.0266
Schistosoma mansoni chromobox protein 0.008 0.0272 0.0275
Brugia malayi MAP kinase sur-1 0.0153 0.0623 0.1158
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.04 0.1814 0.5857
Schistosoma mansoni neuropeptide F-like receptor 0.0206 0.0879 0.0889
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0217 0.0404
Schistosoma mansoni biogenic amine (5HT) receptor 0.0573 0.2647 0.2677
Echinococcus multilocularis ferredoxin adrenodoxin 0.0027 0.0016 0.0016
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0206 0.0879 0.0889
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0077 0.0256 0.0259
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0037 0.0064 0.0065
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0045 0.0103 0.0102
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0206 0.0879 0.0889
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Toxoplasma gondii target of rapamycin (TOR), putative 0.01 0.0369 0.0794
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0038 0.0039
Schistosoma mansoni hypothetical protein 0.0032 0.0038 0.0039
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.04 0.1814 0.5857
Brugia malayi G-protein coupled receptor 0.0206 0.0879 0.1634
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Toxoplasma gondii hypothetical protein 0.0043 0.0089 0.0192
Leishmania major C-8 sterol isomerase-like protein 0.0747 0.3485 0.3485
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0089 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Trypanosoma brucei trypanothione reductase 0.0987 0.4644 0.4644
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0048 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Schistosoma mansoni myosin xvIII 0.0206 0.0879 0.0889
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0043 0.009 0.0166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Mycobacterium ulcerans DNA gyrase subunit A 0.003 0.0027 0.0036
Mycobacterium tuberculosis Probable dehydrogenase 0.0278 0.1225 0.2612
Trichomonas vaginalis glucosylceramidase, putative 0.035 0.1573 0.3956
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0037 0.0063 0.0155
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0849 0.3977 1
Loa Loa (eye worm) hypothetical protein 0.0806 0.3771 0.7652
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0089 0.009
Echinococcus multilocularis NMDA receptor 0.0068 0.0212 0.0214
Chlamydia trachomatis glutamine binding protein 0.0037 0.0063 0.0155
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0135 0.0536 0.0535
Schistosoma mansoni hypothetical protein 0.0145 0.0583 0.059
Echinococcus multilocularis dro:myosuppressin receptor 0.0206 0.0879 0.0889
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.0141 0.0423
Echinococcus multilocularis survival motor neuron protein 1 0.0711 0.3313 0.335
Schistosoma mansoni fkbp-rapamycin associated protein 0.0026 0.0007 0.0007
Schistosoma mansoni inositol monophosphatase 0.0036 0.0059 0.006
Echinococcus granulosus chromobox protein 1 0.008 0.0272 0.0275
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0078 0.0079
Echinococcus multilocularis beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0061 0.018 0.0182
Schistosoma mansoni amine GPCR 0.0206 0.0879 0.0889
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0078 0.0159
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0278 0.1225 0.2612
Entamoeba histolytica tubulin family protein 0.0027 0.0016 0.0057
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0043 0.0089 0.0269
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0206 0.0879 0.0889
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0664 0.3086 0.5738
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0068 0.0068
Brugia malayi nuclear hormone receptor 0.004 0.0078 0.0146
Toxoplasma gondii endonuclease IV APN 0.015 0.0609 0.1312
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0068 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0078 0.0146
Mycobacterium tuberculosis Probable oxidoreductase 0.0766 0.3577 0.7694
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0664 0.3086 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0278 0.1225 0.2612
Schistosoma mansoni hypothetical protein 0.0069 0.0217 0.022
Echinococcus multilocularis g-protein coupled receptor 0.0206 0.0879 0.0889
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0206 0.0879 0.0889
Echinococcus multilocularis potassium large conductance calcium activated 0.0043 0.0089 0.009
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.004 0.0075 0.0193
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0135 0.0533 0.1082
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0083 0.0285 0.0289
Toxoplasma gondii beta-1 tubulin, putative 0.0027 0.0016 0.0034
Trichomonas vaginalis glutathione reductase, putative 0.0664 0.3086 0.7759
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Echinococcus multilocularis mitogen activated protein kinase 3 0.0153 0.0623 0.063
Loa Loa (eye worm) adenylyl cyclase 3 0.0077 0.0253 0.0514
Brugia malayi ion channel NompC 0.0043 0.0089 0.0166
Schistosoma mansoni chromobox protein 0.008 0.0272 0.0275
Onchocerca volvulus 0.0714 0.3326 1
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0176 0.0734 0.1552
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0176 0.0734 0.1845
Echinococcus granulosus epidermal growth factor receptor 0.0149 0.0601 0.0608
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0507 0.2327 0.4723
Schistosoma mansoni glutamate receptor kainate 0.0159 0.0652 0.0659
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0432 0.0437
Echinococcus multilocularis fmrfamide receptor 0.0206 0.0879 0.0889
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0028 0.0021 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0507 0.2327 0.5852
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0068 0.0069
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0068 0.0171
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0176 0.0734 0.0734
Echinococcus multilocularis fmrfamide receptor 0.0206 0.0879 0.0889
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0083 0.0285 0.0289
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0037 0.0064 0.0119
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0135 0.0536 0.0535
Loa Loa (eye worm) SRC-1 0.0077 0.0256 0.052
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus cpg binding protein 0.0062 0.0181 0.0183
Echinococcus multilocularis dnaJ subfamily B 0.0802 0.3754 0.3796
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Plasmodium falciparum ferredoxin, putative 0.0027 0.0016 0.0033
Plasmodium falciparum tubulin beta chain 0.0027 0.0016 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Loa Loa (eye worm) G-protein coupled receptor 0.0206 0.0879 0.1783
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.04 0.1814 0.3885
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0806 0.3771 0.3813
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0078 0.0079
Schistosoma mansoni tyrosine kinase 0.0149 0.0601 0.0608
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0077 0.0256 0.0259
Loa Loa (eye worm) norepinephrine transporter 0.049 0.2248 0.4563
Echinococcus granulosus sex peptide receptor 0.0206 0.0879 0.0889
Toxoplasma gondii beta-tubulin, putative 0.0027 0.0016 0.0034
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0287 0.1266 0.4072
Echinococcus multilocularis 0.0043 0.0089 0.009
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0064 0.0064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0059 0.0058
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0032 0.0053
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0108 0.0403 0.0403
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0078 0.0236
Echinococcus multilocularis neuropeptide Y receptor 0.0206 0.0879 0.0889
Schistosoma mansoni tyrosine kinase 0.0049 0.012 0.0121
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0078 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0133
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0089 0.009
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0432 0.1574
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0028 0.0021 0.0046
Toxoplasma gondii transporter, cation channel family protein 0.006 0.0173 0.0373
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0043 0.0089 0.0269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Schistosoma mansoni opsin-like receptor 0.0206 0.0879 0.0889
Echinococcus granulosus jun protein 0.0083 0.0282 0.0285
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0176 0.0734 0.0742
Echinococcus granulosus voltage gated hydrogen channel 1 0.0043 0.0089 0.009
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0182 0.076 0.0768
Schistosoma mansoni opsin-like receptor 0.0206 0.0879 0.0889
Entamoeba histolytica tubulin family protein 0.0027 0.0016 0.0057
Toxoplasma gondii NADPH-glutathione reductase 0.0664 0.3086 0.6645
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Plasmodium vivax SET domain protein, putative 0.0091 0.0323 0.0695
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0623 0.1566
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0036 0.0056 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0022 0.0045
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0083 0.0285 0.0289
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0089 0.024
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.004 0.0075 0.0225
Onchocerca volvulus 0.0206 0.0879 0.2643
Onchocerca volvulus 0.0206 0.0879 0.2643
Loa Loa (eye worm) hypothetical protein 0.0081 0.0275 0.0558
Loa Loa (eye worm) voltage-gated potassium channel 0.0043 0.0089 0.0181
Brugia malayi ecdysteroid receptor 0.004 0.0078 0.0146
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Echinococcus multilocularis glutamate synthase 0.0176 0.0734 0.0742
Entamoeba histolytica protein kinase, putative 0.0062 0.0184 0.0669
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0077 0.0256 0.0259
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0037 0.0064 0.0065
Schistosoma mansoni rab6-interacting 0.0079 0.0263 0.0266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Schistosoma mansoni sulfide quinone reductase 0.0176 0.0734 0.0742
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0432 0.0876
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0078 0.0159
Echinococcus granulosus 7TM GPCR rhodopsin 0.0206 0.0879 0.0889
Brugia malayi Blistered cuticle protein 3 0.0143 0.0571 0.1062
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0432 0.0432
Onchocerca volvulus 0.0206 0.0879 0.2643
Leishmania major DNA topoisomerase ii 0.013 0.0511 0.0511
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0135 0.0536 0.1953
Loa Loa (eye worm) hypothetical protein 0.0093 0.0332 0.0674
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0176 0.0734 0.0734
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1782 0.8479 0.8479
Mycobacterium ulcerans ferredoxin reductase 0.0176 0.0734 0.234
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0176 0.0734 0.0742
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0135 0.0533 0.0539
Toxoplasma gondii exonuclease III APE 0.0038 0.0068 0.0146
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0068 0.0212 0.0214
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0089 0.0159
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Brugia malayi M-phase phosphoprotein, mpp8 0.0117 0.0448 0.0834
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0593 0.2742 1
Echinococcus multilocularis jun protein 0.0083 0.0282 0.0285
Echinococcus granulosus tubulin subunit beta 0.0027 0.0016 0.0016
Schistosoma mansoni cytochrome P450 0.0043 0.0089 0.009
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.0089 0.0159
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0301 0.0305
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0135 0.0533 0.0992
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Echinococcus multilocularis G protein coupled receptor 139 0.0206 0.0879 0.0889
Echinococcus multilocularis allatostatin A receptor 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.1046 0.4928 1
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Plasmodium falciparum amino acid transporter, putative 0.0083 0.0285 0.0614
Echinococcus multilocularis rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0236 0.0593
Echinococcus multilocularis beta tubulin 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Brugia malayi MH2 domain containing protein 0.0117 0.045 0.0836
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0664 0.3086 0.3086
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0664 0.3086 0.6645
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0135 0.0533 0.0539
Plasmodium vivax multidomain scavenger receptor, putative 0.0079 0.0263 0.0567
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0176 0.0734 0.1552
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0089 0.009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0065 0.0066
Loa Loa (eye worm) glutamate receptor 1 0.0159 0.0652 0.1322
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0027 0.0016 0.0029
Echinococcus granulosus TRP transient receptor potential channel 0.0043 0.0089 0.009
Plasmodium vivax tubulin beta chain, putative 0.0027 0.0016 0.0034
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0176 0.0734 0.234
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0182 0.076 0.0768
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.025 0.0537
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0047 0.01
Echinococcus granulosus neuropeptide FF receptor 2 0.0206 0.0879 0.0889
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0272 0.0551
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0573 0.2647 0.5372
Onchocerca volvulus 0.0145 0.0583 0.1754
Echinococcus granulosus neuropeptides capa receptor 0.0206 0.0879 0.0889
Echinococcus multilocularis neuropeptide receptor 0.0206 0.0879 0.0889
Schistosoma mansoni glutamate receptor kainate 0.0159 0.0652 0.0659
Echinococcus granulosus tubulin beta 1 chain 0.0027 0.0016 0.0016
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0176 0.0734 0.234
Schistosoma mansoni tyrosine kinase 0.0049 0.012 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Loa Loa (eye worm) hypothetical protein 0.0061 0.018 0.0364
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0176 0.0734 0.0742
Echinococcus multilocularis ryanodine receptor 44f 0.0043 0.009 0.0091
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.0089 0.0089
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0176 0.0734 0.0734
Giardia lamblia Thioredoxin reductase 0.0176 0.0734 0.2378
Brugia malayi GnHR receptor homolog 0.0206 0.0879 0.1634
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0059 0.0213
Onchocerca volvulus 0.0206 0.0879 0.2643
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0028 0.0021 0.0021
Loa Loa (eye worm) programmed cell death 8 0.0176 0.0734 0.1489
Trichomonas vaginalis tubulin gamma chain, putative 0.0027 0.0016 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0059 0.0148
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0039 0.005
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0022 0.0048
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0206 0.0879 0.0889
Brugia malayi hypothetical protein 0.0076 0.025 0.0464
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0664 0.3086 0.3086
Echinococcus granulosus two pore calcium channel protein 2 0.0043 0.0089 0.009
Schistosoma mansoni hypothetical protein 0.0043 0.0089 0.009
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0154 0.0628 0.0628
Echinococcus multilocularis cpg binding protein 0.0062 0.0181 0.0183
Plasmodium falciparum transporter, putative 0.0083 0.0285 0.0614
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0137 0.0547 0.1016
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0432 0.0432
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0747 0.3485 0.3485
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0089 0.009
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0022 0.0045
Loa Loa (eye worm) hypothetical protein 0.049 0.2248 0.4563
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Loa Loa (eye worm) tubulin beta-4 chain 0.0027 0.0016 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0038
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0766 0.3577 0.7694
Schistosoma mansoni sodium/chloride dependent transporter 0.0085 0.0292 0.0295
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0119 0.0458 0.1151
Leishmania major ferric reductase, putative 0.0067 0.0207 0.0207
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0077 0.0253 0.0762
Brugia malayi Cytochrome P450 family protein 0.0043 0.0089 0.0166
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Toxoplasma gondii transporter, cation channel family protein 0.0043 0.0089 0.0192
Treponema pallidum NADH oxidase 0.0664 0.3086 1
Onchocerca volvulus 0.0206 0.0879 0.2643
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0206 0.0879 0.1634
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0176 0.0734 0.0742
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0323 0.0326
Treponema pallidum hypothetical protein 0.0138 0.0549 0.1709
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0105 0.0391 0.0396
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0061 0.018 0.0182
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0176 0.0734 0.1365
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Brugia malayi 6-phosphofructokinase 0.0114 0.0434 0.0806
Schistosoma mansoni glutamate receptor AMPA 0.0159 0.0652 0.0659
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0509 0.0514
Echinococcus granulosus neuropeptide receptor A26 0.1109 0.5231 0.529
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0078 0.0079
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0287 0.1266 0.2701
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0022 0.0041
Loa Loa (eye worm) ion channel NompC 0.0043 0.0089 0.0181
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni bromodomain containing protein 0.0069 0.0218 0.0221
Loa Loa (eye worm) hypothetical protein 0.0083 0.0285 0.0579
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Onchocerca volvulus 0.0065 0.0197 0.0591
Brugia malayi Cyclic-nucleotide gated cation channel 0.0061 0.018 0.0334
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0076 0.0077
Brugia malayi SRC-1 0.0077 0.0256 0.0476
Brugia malayi PHD-finger family protein 0.0029 0.0022 0.0041
Giardia lamblia Beta tubulin 0.0027 0.0016 0.0051
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0059 0.0058
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0038 0.0077
Trichomonas vaginalis set domain proteins, putative 0.0713 0.3324 0.8359
Echinococcus granulosus lipoxygenase domain containing protein 0.0079 0.0263 0.0266
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.012 0.0122
Onchocerca volvulus 0.0083 0.0285 0.0858
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0402 0.1011
Schistosoma mansoni thyroid hormone receptor 0.004 0.0078 0.0079
Schistosoma mansoni hypothetical protein 0.0087 0.0301 0.0305
Trypanosoma cruzi DNA topoisomerase II, putative 0.013 0.0511 0.0511
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0032 0.0069
Echinococcus granulosus hypothetical protein 0.0043 0.0089 0.009
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0089 0.009
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0244 0.0246
Schistosoma mansoni sodium/chloride dependent transporter 0.049 0.2248 0.2274
Brugia malayi CHD4 protein 0.0028 0.0021 0.0038
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0176 0.0734 0.1845
Brugia malayi hypothetical protein 0.0043 0.0089 0.0166
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0059 0.0147
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0287 0.1266 0.4072
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0039 0.0071
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0135 0.0533 0.0539
Mycobacterium ulcerans glutamate synthase subunit beta 0.0176 0.0734 0.234
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0176 0.0734 0.158
Schistosoma mansoni tyrosine kinase 0.0078 0.026 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0127 0.0318
Mycobacterium ulcerans hypothetical protein 0.0176 0.0734 0.234
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0067 0.0207 0.0207
Echinococcus multilocularis neuropeptide s receptor 0.1109 0.5231 0.529
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.025 0.0537
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0022 0.0041
Schistosoma mansoni amine GPCR 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Schistosoma mansoni microtubule-associated protein tau 0.2075 0.9889 1
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0135 0.0533 0.0539
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0206 0.0879 0.1634
Onchocerca volvulus 0.0149 0.0601 0.1807
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0083 0.0285 0.0288
Onchocerca volvulus 0.0043 0.0089 0.0269
Brugia malayi larval opioid receptor 0.0206 0.0879 0.1634
Schistosoma mansoni sodium/chloride dependent transporter 0.0083 0.0285 0.0288
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.0229 0.0231
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0028 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Trypanosoma cruzi target of rapamycin kinase 3 0.0108 0.0403 0.0403
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0301 0.0305
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0068 0.0068
Echinococcus granulosus orexin receptor type 2 0.0206 0.0879 0.0889
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0039 0.0038
Onchocerca volvulus 0.0206 0.0879 0.2643
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0252 0.1097 0.3523
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0047 0.01
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0061 0.018 0.0182
Echinococcus granulosus mitogen activated protein kinase 3 0.0153 0.0623 0.063
Echinococcus granulosus insulin receptor 0.0049 0.012 0.0122
Echinococcus granulosus tyrosine protein kinase Fyn 0.0077 0.0256 0.0259
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.029 0.128 0.2732
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0206 0.0879 0.1634
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0077 0.0256 0.0259
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0509 0.1854
Leishmania major cytochrome p450-like protein 0.0043 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0043 0.0091 0.0185
Trypanosoma cruzi adrenodoxin precursor, putative 0.0027 0.0016 0.0015
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0043 0.0089 0.0192
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0135 0.0536 0.0542
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0026 0.0007 0.0007
Brugia malayi Pre-SET motif family protein 0.0627 0.2907 0.5407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0103 0.0258
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0083 0.0285 0.0531
Loa Loa (eye worm) hypothetical protein 0.0209 0.0892 0.181
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0068 0.0135
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0089 0.009
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0206 0.0879 0.1783
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0047 0.0047
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0039 0.0039
Leishmania major ferredoxin 2fe-2s-like protein 0.0027 0.0016 0.0015
Brugia malayi G-protein coupled receptor 0.0206 0.0879 0.1634
Onchocerca volvulus 0.0081 0.0275 0.0827
Leishmania major hypothetical protein, conserved 0.0176 0.0734 0.0734
Trichomonas vaginalis glucosylceramidase, putative 0.0507 0.2327 0.5852
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0372 0.0754
Plasmodium falciparum DNA gyrase subunit B 0.008 0.027 0.0582
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0083 0.0285 0.0288
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0206 0.0879 0.0889
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0061 0.018 0.0182
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0032 0.008
Brugia malayi putative neuropeptide receptor NPR1 0.0206 0.0879 0.1634
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Echinococcus granulosus adenylate cyclase 9 0.0077 0.0253 0.0256
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0059 0.0142
Echinococcus granulosus potassium voltage gated channel subfamily H 0.015 0.0609 0.0616
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0623 0.1566
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0078 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0021 0.0053
Plasmodium falciparum DNA topoisomerase 2 0.0137 0.0547 0.1177
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0216 0.0439
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0488 0.2236 0.4158
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0078 0.0146
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0064 0.0161
Brugia malayi cytochrome P450 0.0043 0.0089 0.0166
Brugia malayi Tubulin beta-1 chain 0.0027 0.0016 0.0029
Echinococcus multilocularis chromobox protein 1 0.008 0.0272 0.0275
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0045 0.0103 0.0104
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0285 0.0614
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0157
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0176 0.0734 0.158
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0664 0.3086 0.6645
Entamoeba histolytica disulphide oxidoreductase, putative 0.0176 0.0734 0.2676
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0089 0.009
Brugia malayi Glutamate receptor 2 precursor 0.0159 0.0652 0.1211
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Echinococcus multilocularis tyrosine protein kinase HCK 0.0062 0.0184 0.0186
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0032 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0509 0.0508
Entamoeba histolytica hypothetical protein 0.0097 0.0351 0.1279
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0432 0.0876
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0206 0.0879 0.0889
Schistosoma mansoni tyrosine kinase 0.0078 0.026 0.0263
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0076 0.0077
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0081 0.0274 0.0277
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0278 0.0281
Schistosoma mansoni rab6-interacting 0.0079 0.0263 0.0266
Brugia malayi N-terminal motif family protein 0.0203 0.0864 0.1607
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0038
Chlamydia trachomatis DNA gyrase subunit B 0.008 0.027 0.083
Schistosoma mansoni hypothetical protein 0.0206 0.0879 0.0889
Trichomonas vaginalis tubulin alpha chain, putative 0.0027 0.0016 0.0039
Schistosoma mansoni transient receptor potential channel 0.0043 0.0089 0.009
Schistosoma mansoni hypothetical protein 0.0087 0.0301 0.0305
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0089 0.009
Echinococcus granulosus sodium and chloride dependent glycine 0.0083 0.0285 0.0289
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0141 0.0353
Echinococcus granulosus hypothetical protein 0.1606 0.7627 0.7712
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0176 0.0734 0.234
Loa Loa (eye worm) neuropeptide F receptor 0.0206 0.0879 0.1783
Onchocerca volvulus 0.0056 0.0156 0.0468
Loa Loa (eye worm) hypothetical protein 0.0029 0.0022 0.0045
Echinococcus granulosus biogenic amine 5HT receptor 0.1315 0.6224 0.6294
Loa Loa (eye worm) hypothetical protein 0.0056 0.0154 0.0311
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.029 0.128 0.3505
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0059 0.0059
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0206 0.0879 0.0889
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0089 0.009
Brugia malayi G protein-coupled receptor F59B2.13 0.0206 0.0879 0.1634
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Brugia malayi Cytochrome P450 family protein 0.0069 0.0216 0.0402
Leishmania major hypothetical protein, conserved 0.0027 0.0016 0.0015
Onchocerca volvulus Glucosylceramidase homolog 0.0332 0.1487 0.4471
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0108 0.0403 0.0403
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0056 0.0155 0.0155
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0059 0.0059
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.008 0.027 0.055
Brugia malayi AKH receptor 0.0206 0.0879 0.1634
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0078 0.0236
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0182 0.076 0.0768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0536 0.1346
Loa Loa (eye worm) voltage-dependent calcium channel 0.006 0.0173 0.0351
Schistosoma mansoni amine GPCR 0.1041 0.4903 0.4958
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0068 0.0068
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0043 0.0089 0.009
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0043 0.0089 0.0166
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0176 0.0734 0.1365
Entamoeba histolytica thioredoxin reductase, putative 0.0176 0.0734 0.2676
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0103 0.0208
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0206 0.0879 0.0889
Entamoeba histolytica hypothetical protein 0.0026 0.0007 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0083 0.0285 0.0288
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0007 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0032 0.008
Mycobacterium ulcerans DNA gyrase subunit B 0.008 0.027 0.083
Echinococcus granulosus voltage gated potassium channel 0.0071 0.0229 0.0231
Trichomonas vaginalis glutamate synthase, putative 0.0176 0.0734 0.1845
Schistosoma mansoni ap endonuclease 0.0038 0.0068 0.0069
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0045 0.0103 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0206 0.0879 0.0889
Schistosoma mansoni biogenic amine receptor 0.0206 0.0879 0.0889
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0032 0.0069
Echinococcus granulosus intermediate filament protein 0.0081 0.0275 0.0278
Loa Loa (eye worm) serotonin transporter b 0.049 0.2248 0.4563
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Echinococcus multilocularis transfer RNA-Gly 0.0043 0.0089 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0332 0.1487 0.3739
Echinococcus multilocularis nmda type glutamate receptor 0.0183 0.0765 0.0774
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0091 0.0092
Schistosoma mansoni hypothetical protein 0.0032 0.0038 0.0039
Trypanosoma cruzi trypanothione reductase, putative 0.0987 0.4644 0.4644
Onchocerca volvulus 0.0206 0.0879 0.2643
Loa Loa (eye worm) hypothetical protein 0.0071 0.0229 0.0464
Loa Loa (eye worm) hypothetical protein 0.0093 0.0332 0.0674
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0089 0.0089
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0067 0.0207 0.0207
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0432 0.0899
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0043 0.0089 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0078 0.0146
Trypanosoma cruzi NADH dehydrogenase, putative 0.0176 0.0734 0.0734
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0089 0.024
Echinococcus multilocularis adenylate cyclase 9 0.0077 0.0253 0.0256
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0176 0.0734 0.1845
Loa Loa (eye worm) hypothetical protein 0.003 0.0029 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.2742 0.6895
Brugia malayi Probable DNA topoisomerase II 0.0137 0.0547 0.1016
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0176 0.0734 0.1552
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0176 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0043
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0089 0.009
Onchocerca volvulus 0.0206 0.0879 0.2643
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Trypanosoma cruzi hypothetical protein, conserved 0.0176 0.0734 0.0734
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0089 0.009
Echinococcus granulosus 7tm_1 domain containing protein 0.0206 0.0879 0.0889
Echinococcus granulosus lipoxygenase domain containing protein 0.0079 0.0263 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0103 0.0258
Brugia malayi chromobox protein homolog 3 0.005 0.0127 0.0235
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0083 0.0285 0.0289
Schistosoma mansoni glutamate synthase 0.0176 0.0734 0.0742
Trichomonas vaginalis Ferredoxin 3 0.0027 0.0016 0.0039
Echinococcus granulosus Polycystic kidney disease protein 0.0079 0.0263 0.0266
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0039 0.0039
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0034
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0083 0.0285 0.0288
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0169 0.0343
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0156 0.0316
Leishmania major hypothetical protein, conserved 0.0076 0.025 0.0249
Echinococcus granulosus tyrosine protein kinase Lyn 0.0079 0.0263 0.0266
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0747 0.3485 0.648
Brugia malayi nuclear receptor NHR-88 0.004 0.0078 0.0146
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0078 0.0079
Loa Loa (eye worm) TK/EGFR protein kinase 0.0149 0.0601 0.122
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0077 0.0256 0.0259
Echinococcus multilocularis glutamate receptor 2 0.0114 0.0432 0.0436
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0206 0.0879 0.0889
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0664 0.3086 0.6645
Echinococcus multilocularis glutamate receptor 2 0.0182 0.076 0.0768
Giardia lamblia DNA repair protein RAD52 0.034 0.1525 0.4942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0321 0.0807
Plasmodium falciparum glutathione reductase 0.0664 0.3086 0.6645
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.0089 0.024
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0509 0.0945
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0015
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Brugia malayi CXXC zinc finger family protein 0.0056 0.0156 0.0289
Giardia lamblia GTOR 0.0135 0.0536 0.1735
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.025 0.0249
Onchocerca volvulus 0.0114 0.0434 0.1306
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0083 0.0285 0.0289
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0098 0.0355 0.0355
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0043 0.0089 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Brugia malayi steroid hormone receptor 0.004 0.0078 0.0146
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0089 0.009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0078 0.0146
Echinococcus granulosus tm gpcr rhodopsin 0.1885 0.8977 0.9077
Loa Loa (eye worm) BEN-1 protein 0.0027 0.0016 0.0032
Onchocerca volvulus 0.0206 0.0879 0.2643
Leishmania major hypothetical protein, conserved 0.0176 0.0734 0.0734
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0027 0.0016 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0153 0.0623 0.0623
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0037 0.0063 0.012
Echinococcus multilocularis 0.0045 0.0103 0.0104
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0181
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0627 0.2907 0.59
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0059 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.035 0.1573 0.3956
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0068 0.0212 0.0214
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0427 0.0918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0402 0.1011
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.012 0.0122
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0153 0.0623 0.0623
Brugia malayi Tachykinin-like peptides receptor 99D 0.0206 0.0879 0.1634
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0509 0.0514
Echinococcus multilocularis serotonin receptor 0.0573 0.2647 0.2677
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0206 0.0879 0.0889
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0068 0.0212 0.0214
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0057 0.0143
Schistosoma mansoni hypothetical protein 0.0802 0.3754 0.3795
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0432 0.1574
Echinococcus granulosus geminin 0.0509 0.2341 0.2367
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0153 0.0623 0.1341
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0037 0.0063 0.0155
Echinococcus multilocularis two pore calcium channel protein 2 0.0043 0.0089 0.009
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0135 0.0533 0.0539
Echinococcus multilocularis tumor protein p63 0.1016 0.4783 0.4837
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.0091 0.0092
Mycobacterium tuberculosis Probable reductase 0.0278 0.1225 0.2612
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0039 0.0083
Brugia malayi Serotonin receptor 0.1139 0.5378 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0206 0.0879 0.0889
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.015 0.0609 0.1235
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0162 0.0665 0.2117
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0176 0.0734 0.158
Echinococcus granulosus potassium large conductance calcium activated 0.0043 0.0089 0.009
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0089 0.009
Brugia malayi Augmenter of liver regeneration 0.0034 0.0047 0.0087
Loa Loa (eye worm) hypothetical protein 0.0382 0.1724 0.3499
Echinococcus granulosus chromobox protein 1 0.008 0.0272 0.0275
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0077 0.0256 0.0259
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0593 0.2742 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0089 0.024
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0089 0.009
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0083 0.0285 0.0288
Onchocerca volvulus 0.0206 0.0879 0.2643
Leishmania major hypothetical protein, conserved 0.0034 0.0047 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0206 0.0879 0.0889
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0078 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.016 0.0658 0.0665
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0182 0.076 0.0768
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0176 0.0734 0.0734
Trypanosoma cruzi trypanothione reductase, putative 0.0664 0.3086 0.3086
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.0337 0.0341
Loa Loa (eye worm) TK protein kinase 0.0062 0.0184 0.0372
Echinococcus granulosus somatostatin receptor 0.0206 0.0879 0.0889
Schistosoma mansoni protein kinase 0.0029 0.0022 0.0022
Brugia malayi putative neuropeptide receptor 0.0206 0.0879 0.1634
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0089 0.009
Brugia malayi RE15519p 0.0206 0.0879 0.1634
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.007 0.022 0.0223
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0089 0.0159
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0078 0.0079
Plasmodium vivax DNA topoisomerase II, putative 0.0137 0.0547 0.1177
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0039 0.0078
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.0089 0.0089
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0083 0.0285 0.0288
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0206 0.0879 0.0889
Brugia malayi ORL1-like opioid receptor 0.0206 0.0879 0.1634
Toxoplasma gondii hypothetical protein 0.0043 0.0089 0.0192
Loa Loa (eye worm) hypothetical protein 0.0206 0.0879 0.1783
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0089 0.009
Schistosoma mansoni sodium-dependent amino acid transporter 0.0083 0.0285 0.0288
Echinococcus granulosus dro:myosuppressin receptor 0.0206 0.0879 0.0889
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0089 0.009
Echinococcus granulosus glutamate receptor subunit protein glur 0.0068 0.0212 0.0214
Brugia malayi hypothetical protein 0.0206 0.0879 0.1634
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0235 0.0591
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0109 0.0409 0.0413
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0206 0.0879 0.1783
Loa Loa (eye worm) cytochrome P450 0.0043 0.0089 0.0181
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0043 0.0089 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0369 0.0927
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0159
Onchocerca volvulus 0.0206 0.0879 0.2643
Loa Loa (eye worm) hypothetical protein 0.008 0.0268 0.0543
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0061 0.018 0.0364
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.02 0.0203
Trichomonas vaginalis glucosylceramidase, putative 0.0507 0.2327 0.5852
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0176 0.0734 0.2676
Trypanosoma brucei electron transfer protein, putative 0.0027 0.0016 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0089 0.0159
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0278 0.0281
Schistosoma mansoni alpha-1 adrenergic receptor 0.0206 0.0879 0.0889
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1782 0.8479 0.8479
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0409 0.1856 0.1876
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0078 0.0159
Brugia malayi Thioredoxin reductase 0.0987 0.4644 0.8635
Giardia lamblia Glutamate synthase 0.0176 0.0734 0.2378
Echinococcus granulosus biogenic amine 5HT receptor 0.0573 0.2647 0.2677
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0057 0.0143
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0027 0.0016 0.0033
Echinococcus granulosus two pore calcium channel protein 1 0.0043 0.0089 0.009
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0216 0.0439
Trypanosoma brucei C-8 sterol isomerase, putative 0.0747 0.3485 0.3485

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 20 nM Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulation ChEMBL. 12639550
EC50 (functional) = 20 nM Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulation ChEMBL. 12639550
EC50 (functional) = 20 nM Effective concentration against hMC1R using HEK293 cells was determined by measuring the cAMP accumulation ChEMBL. 12639550
EC50 (functional) = 20 nM Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulation ChEMBL. 12639550
IC50 (binding) = 80 nM Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cells ChEMBL. 12639550
IC50 (binding) = 80 nM Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cells ChEMBL. 12639550
IC50 (binding) = 300 nM Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cells ChEMBL. 12639550
IC50 (binding) = 300 nM Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cells ChEMBL. 12639550

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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