Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0603 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.8876 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.1014 | 0.0453 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7379 | 0.7362 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.7379 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0191 | 0.0127 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0.0064 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4722 | 0.4688 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Onchocerca volvulus | 0.0032 | 0.4439 | 0.5 | |
Trypanosoma cruzi | ISWI complex protein | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7379 | 0.7362 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4439 | 0.4403 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4722 | 0.6015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.1014 | 0.0453 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4439 | 0.5396 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trypanosoma brucei | ISWI complex protein | 0.0003 | 0 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.7379 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0603 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4439 | 0.5381 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4722 | 0.4688 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.7379 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.7379 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.7379 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.7379 | 0.7362 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0004 | 0.0082 | 0.1363 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0.0064 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0711 | 0.0651 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.7379 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4722 | 0.6015 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Kd (binding) | = 308 uM | Binding affinity for the 16S ribosomal RNA A-site of Escherichia coli | ChEMBL. | 14741271 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.