Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0066 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0017 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0066 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0017 | 0 | 0.5 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MAP (functional) | = 15 mmHg | Tested for maximum fall in mean arterial pressure in Spontaneously hypertensive rats after peroral administration by using 1% methyl cellulose as vehicle at 20 mg/kg | ChEMBL. | 6102151 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.