Detailed information for compound 27599

Basic information

Technical information
  • TDR Targets ID: 27599
  • Name: Vinblastine
  • MW: 810.974 | Formula: C46H58N4O9
  • H donors: 3 H acceptors: 5 LogP: 4.74 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc2N(C)[C@@H]3[C@@]4(c2cc1[C@]1(C[C@@H]2CN(CCc5c1[nH]c1c5cccc1)C[C@](C2)(O)CC)C(=O)OC)CCN1[C@H]4[C@@]([C@H]([C@]3(O)C(=O)OC)OC(=O)C)(CC)C=CC1
  • InChi: 1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1
  • InChiKey: JXLYSJRDGCGARV-XQKSVPLYSA-N  

Network

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Synonyms

  • 865-21-4
  • 143-67-9 (SULFATE)
  • AIDS-002673
  • AIDS002673
  • NCI60_004200
  • CHEBI:27375
  • C07201
  • STOCK1N-71217

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major delta tubulin, putative Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major gamma-tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major zeta tubulin, putative Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Plasmodium falciparum tubulin beta chain Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major epsilon tubulin, putative Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica tubulin alpha-1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K10389 tubulin gamma, putative Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit gamma Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania donovani tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Brugia malayi beta-tubulin, identical Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium knowlesi tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium berghei tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum Beta-tubulin, related Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium berghei alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin alpha chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Brugia malayi Tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium berghei tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Schistosoma mansoni tubulin subunit epsilon Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium hominis beta-catenin-like repeat protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha-3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Babesia bovis tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha-tubulin II, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-1C chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta-4 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania mexicana gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin, beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Toxoplasma gondii beta-1 tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_143817 All targets in OG5_143817
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium hominis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium falciparum alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-2A chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium berghei tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium berghei alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii alpha tubulin TUBA1 Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Candida albicans cytoskeletal structural protein Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Trypanosoma congolense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-2/alpha-4 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium falciparum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania donovani tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K10391 tubulin epsilon, putative Get druggable targets OG5_130726 All targets in OG5_130726
Toxoplasma gondii beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_127652 All targets in OG5_127652
Cryptosporidium parvum gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Brugia malayi Tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-7 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_130726 All targets in OG5_130726
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_130726 All targets in OG5_130726
Loa Loa (eye worm) tubulin beta-4 chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta-tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium knowlesi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Theileria parva tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii Tubulin/FtsZ family, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin isotype 2 Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin delta chain, putative Get druggable targets OG5_143817 All targets in OG5_143817
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Theileria parva tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii alpha-tubulin I, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi tubulin alpha chain - mouse Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium parvum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma congolense tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma congolense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania donovani zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi beta tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain tubulin beta chain 445 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin epsilon chain, putative gamma-tubulin 447 aa 479 aa 28.2 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Trypanosoma brucei epsilon tubulin epsilon tubulin, putative 470 aa 488 aa 68.0 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Schistosoma mansoni ets-related 0.0215 0.0308 0.0308
Echinococcus granulosus tumor protein p63 0.0408 0.0621 0.1846
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.005 0.0281
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0299 0.0444 0.1304
Schistosoma mansoni alpha-1 adrenergic receptor 0.0434 0.0663 0.0662
Echinococcus granulosus GPCR family 2 0.0348 0.0523 0.1554
Echinococcus multilocularis orexin receptor type 2 0.0434 0.0663 0.168
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Schistosoma mansoni patched 1 0.0086 0.0098 0.0098
Leishmania major beta tubulin 0.0997 0.1578 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.005 0.0146
Brugia malayi aspartic protease BmAsp-2, identical 0.0495 0.0764 0.276
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0061 0.0057 0.0142
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0114 0.0143 0.0515
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0204 0.029 0.2498
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Echinococcus multilocularis g protein coupled receptor 0.0434 0.0663 0.168
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0054 0.0053
Brugia malayi jmjC domain containing protein 0.0051 0.0041 0.0145
Brugia malayi Doublecortin family protein 0.0071 0.0074 0.0267
Brugia malayi Serotonin receptor 0.0434 0.0663 0.2396
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.002 0.0125
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0037 0.0133
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0065 0.0064 0.0161
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0058 0.0058
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0431 0.2707
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0001 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0163 0.1655
Schistosoma mansoni DNA ligase IV 0.0029 0.0005 0.0005
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0067 0.0068 0.0199
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0058 0.0157
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0052 0.0044 0.0109
Plasmodium falciparum tubulin beta chain 0.0997 0.1578 0.4691
Echinococcus granulosus Tubulin alpha 1 chain 0.0739 0.116 0.3447
Leishmania major cytochrome p450-like protein 0.0097 0.0117 0.0644
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trypanosoma cruzi pyruvate kinase 2, putative 0.0074 0.0078 0.0461
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0028 0.0027
Schistosoma mansoni adenoreceptor 0.0434 0.0663 0.0662
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0046 0.0033 0.0591
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Onchocerca volvulus 0.0067 0.0068 0.043
Plasmodium falciparum plasmepsin X 0.0495 0.0764 0.227
Schistosoma mansoni gabp alpha 0.0071 0.0074 0.0073
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0069 0.034
Onchocerca volvulus 0.0039 0.0022 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0072 0.0075 0.027
Echinococcus multilocularis dna polymerase eta 0.0038 0.002 0.0048
Echinococcus multilocularis g-protein coupled receptor 0.0434 0.0663 0.168
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0088 0.0101 0.0299
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.014 0.1142
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0015
Loa Loa (eye worm) TYRA-2 protein 0.0434 0.0663 0.1969
Echinococcus granulosus tubulin alpha 3 chain 0.0739 0.116 0.3447
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Onchocerca volvulus 0.0067 0.0068 0.043
Echinococcus granulosus lipoxygenase domain containing protein 0.0071 0.0074 0.0219
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0044 0.0155
Schistosoma mansoni growth hormone secretagogue receptor 0.0434 0.0663 0.0662
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0114 0.0143 0.0515
Schistosoma mansoni amine oxidase 0.0043 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0049
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0072 0.0075 0.0222
Echinococcus multilocularis serotonin transporter 0.0253 0.037 0.0936
Echinococcus granulosus expressed conserved protein 0.0188 0.0264 0.0784
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Trypanosoma cruzi tubulin delta chain 0.0453 0.0695 0.4385
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Echinococcus multilocularis glycine receptor subunit beta 0.0114 0.0143 0.0361
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0214 0.0305 0.0773
Loa Loa (eye worm) G protein alpha subunit 3 0.0039 0.0022 0.0064
Plasmodium falciparum plasmepsin IX 0.0495 0.0764 0.227
Echinococcus multilocularis pyruvate kinase 0.0038 0.002 0.0048
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0078 0.023
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0434 0.0663 0.1969
Onchocerca volvulus 0.0067 0.0068 0.043
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0016 0.0031
Echinococcus multilocularis tubulin alpha 1C chain 0.0739 0.116 0.2941
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0434 0.0663 0.1969
Loa Loa (eye worm) tubulin alpha 2 0.0189 0.0266 0.0788
Giardia lamblia GTOR 0.0054 0.0047 0.0261
Echinococcus granulosus lamin b receptor 0.0098 0.0118 0.035
Trichomonas vaginalis ran, putative 0.0088 0.0101 0.0283
Trypanosoma brucei glucosidase, putative 0.0035 0.0016 0.0101
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0053 0.019
Schistosoma mansoni phd/f-box containing protein 0.0051 0.0041 0.004
Schistosoma mansoni alpha tubulin 0.0739 0.116 0.1159
Treponema pallidum cell division protein FtsZ 0.0252 0.0367 0.7902
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.0163 0.0411
Toxoplasma gondii beta-1 tubulin, putative 0.0997 0.1578 0.4682
Schistosoma mansoni tubulin subunit alpha 0.0739 0.116 0.1159
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0046 0.0033 0.017
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.2095 0.3364 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Echinococcus granulosus neuropeptides capa receptor 0.0434 0.0663 0.1969
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0072 0.0075 0.0222
Loa Loa (eye worm) hypothetical protein 0.0088 0.0101 0.0298
Schistosoma mansoni ran 0.0088 0.0101 0.01
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0017 0.0121
Echinococcus granulosus microtubule associated protein 2 0.1364 0.2175 0.6465
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0434 0.0663 0.1969
Schistosoma mansoni eyes absent homolog 0.0088 0.0101 0.01
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.2095 0.3364 1
Brugia malayi Bromodomain containing protein 0.0069 0.0071 0.0255
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0059 0.0177
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0013 0.0082
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0114 0.0143 0.0361
Echinococcus granulosus Tubulin beta 2C chain 0.0997 0.1578 0.469
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0013 0.0082
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0027
Leishmania major beta tubulin 0.0997 0.1578 1
Onchocerca volvulus Huntingtin homolog 0.0122 0.0157 0.0998
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0037 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0072 0.0075 0.027
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0058 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.002 0.0057
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0061 0.0058 0.0207
Schistosoma mansoni smad1 5 8 and 0.0058 0.0053 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0015
Onchocerca volvulus 0.0434 0.0663 0.4242
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0071 0.0074 0.0725
Loa Loa (eye worm) latrophilin receptor protein 2 0.0348 0.0523 0.1555
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.0013 0.0032
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 0.1378
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0072 0.0075 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Echinococcus granulosus ecdysone induced protein 78C 0.0072 0.0075 0.0222
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.005 0.0465
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0046 0.0033 0.0285
Giardia lamblia Beta tubulin 0.0997 0.1578 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0041 0.0119
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0114 0.0143 0.0423
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.0013 0.0032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0714 0.1118 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0062 0.0059 0.0149
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0163 0.1655
Mycobacterium leprae conserved hypothetical protein 0.0112 0.014 0.2707
Plasmodium falciparum plasmepsin VI 0.2095 0.3364 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0071 0.0074 0.0725
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0039 0.0022 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0016 0.003
Echinococcus granulosus pyruvate kinase 0.0074 0.0078 0.023
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0071 0.0074 0.0725
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0114 0.0143 0.0424
Onchocerca volvulus 0.0114 0.0143 0.0912
Schistosoma mansoni opsin-like receptor 0.0434 0.0663 0.0662
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0434 0.0663 0.168
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0061 0.0058 0.0057
Trypanosoma brucei epsilon tubulin 0.0582 0.0905 0.5735
Echinococcus multilocularis peroxisome assembly protein 26 0.0739 0.116 0.2941
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0071 0.0074 0.0549
Schistosoma mansoni hypothetical protein 0.0434 0.0663 0.0662
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0043 0.0029 0.0242
Brugia malayi alpha-tubulin 0.0739 0.116 0.4195
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0997 0.1578 0.4001
Trichomonas vaginalis tubulin beta chain, putative 0.0739 0.116 0.3438
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0114 0.0143 0.0424
Entamoeba histolytica hypothetical protein 0.0096 0.0115 0.0696
Brugia malayi amine oxidase, flavin-containing family protein 0.0043 0.0029 0.0101
Leishmania major beta tubulin 0.0997 0.1578 1
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0613 0.0955 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0047 0.0166
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.2095 0.3364 0.3364
Trypanosoma cruzi sterol C-24 reductase, putative 0.0098 0.0118 0.0717
Loa Loa (eye worm) hypothetical protein 0.006 0.0055 0.0163
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0071 0.0074 0.0374
Onchocerca volvulus 0.0043 0.0029 0.0178
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0033 0.0172
Plasmodium falciparum ataxin-2 like protein, putative 0.0208 0.0297 0.0882
Leishmania major beta tubulin 0.0997 0.1578 1
Brugia malayi hypothetical protein 0.0052 0.0044 0.0155
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0029 0.0146
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.002 0.0049
Schistosoma mansoni polycystin 1-related 0.0071 0.0074 0.0074
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0037 0.033
Trichomonas vaginalis tubulin alpha chain, putative 0.0299 0.0444 0.1304
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0301 0.0447 0.3926
Entamoeba histolytica tubulin family protein 0.0997 0.1578 1
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus glycine receptor subunit alpha 1 0.0114 0.0143 0.0423
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Leishmania major beta tubulin 0.0997 0.1578 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Brugia malayi Importin beta-1 subunit 0.0119 0.0152 0.0546
Leishmania major GTP-binding protein, putative 0.0088 0.0101 0.0541
Treponema pallidum sodium- and chloride- dependent transporter 0.0253 0.037 0.7948
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0049 0.0174
Loa Loa (eye worm) MH1 domain-containing protein 0.0058 0.0053 0.0156
Toxoplasma gondii isocitrate dehydrogenase 0.0065 0.0064 0.0175
Mycobacterium tuberculosis Probable oxidoreductase 0.0334 0.0502 0.442
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0017 0.005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0011 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0075 0.0075
Echinococcus multilocularis Tubulin alpha 1 chain 0.0739 0.116 0.2941
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0071 0.0074 0.0438
Echinococcus granulosus serotonin transporter 0.0253 0.037 0.1097
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0033 0.0082
Onchocerca volvulus Neuropeptide F receptor homolog 0.0434 0.0663 0.4242
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0033 0.0117
Echinococcus granulosus neuropeptides capa receptor 0.0434 0.0663 0.1969
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0039 0.0022 0.0078
Echinococcus granulosus replication factor c subunit 1 0.0029 0.0005 0.0014
Brugia malayi ORL1-like opioid receptor 0.0434 0.0663 0.2396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Echinococcus multilocularis tubulin alpha 3 chain 0.0739 0.116 0.2941
Leishmania major hypothetical protein, conserved 0.0051 0.0041 0.0158
Schistosoma mansoni neuropeptide f receptor 76f 0.0434 0.0663 0.0662
Giardia lamblia Alpha-tubulin 0.0739 0.116 0.7342
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0311 0.0464 0.1174
Echinococcus granulosus survival motor neuron protein 1 0.071 0.1112 0.3306
Echinococcus granulosus biogenic amine 5HT receptor 0.0434 0.0663 0.1969
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.014 0.04
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0046 0.0033 0.0097
Brugia malayi nuclear receptor NHR-88 0.0034 0.0013 0.0046
Schistosoma mansoni biogenic amine (5HT) receptor 0.0434 0.0663 0.0662
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0049 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0039 0.0022 0.0022
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0033 0.0082
Schistosoma mansoni lipoxygenase 0.0147 0.0198 0.0197
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.009
Brugia malayi cytochrome P450 0.0071 0.0074 0.0267
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0039 0.0022 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Plasmodium vivax multidomain scavenger receptor, putative 0.0071 0.0074 0.0221
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0046 0.0033 0.0095
Plasmodium falciparum plasmepsin VIII, putative 0.0495 0.0764 0.227
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0039 0.0022 0.005
Loa Loa (eye worm) hypothetical protein 0.0074 0.0078 0.023
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0072 0.0075 0.0075
Brugia malayi Tubulin alpha-2 chain 0.0739 0.116 0.4195
Brugia malayi Pre-SET motif family protein 0.0612 0.0953 0.3445
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0052 0.0044 0.0127
Trichomonas vaginalis tubulin epsilon chain, putative 0.0997 0.1578 0.4682
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0049 0.0037 0.0094
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1099 0.1744 0.6309
Brugia malayi Cell division protein ftsZ 0.0252 0.0367 0.1327
Schistosoma mansoni biogenic amine (5HT) receptor 0.0434 0.0663 0.0662
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Echinococcus multilocularis tubulin gamma 1 chain 0.0583 0.0906 0.2296
Brugia malayi Tubulin beta-1 chain 0.0997 0.1578 0.5707
Brugia malayi Dopamine receptor protein 2 0.0434 0.0663 0.2396
Schistosoma mansoni glutamate receptor NMDA 0.0061 0.0057 0.0056
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0037 0.0199
Onchocerca volvulus 0.0253 0.037 0.2363
Schistosoma mansoni amine oxidase 0.0043 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0104 0.0261
Brugia malayi Carboxylesterase family protein 0.0131 0.0172 0.0619
Entamoeba histolytica hypothetical protein 0.0061 0.0058 0.0333
Schistosoma mansoni smad1 5 8 and 0.0058 0.0053 0.0052
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0016 0.0045
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0058 0.0336
Brugia malayi SWIRM domain containing protein 0.0043 0.0029 0.0101
Brugia malayi hypothetical protein 0.0052 0.0044 0.0155
Onchocerca volvulus 0.0434 0.0663 0.4242
Echinococcus granulosus alpha tubulin 0.0739 0.116 0.3447
Brugia malayi hypoxia-induced factor 1 0.0182 0.0254 0.0916
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0029 0.0072
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Brugia malayi Cation transporter family protein 0.0114 0.0143 0.0515
Trypanosoma brucei beta tubulin 0.0997 0.1578 1
Onchocerca volvulus 0.0434 0.0663 0.4242
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0058 0.0157
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trypanosoma cruzi cytochrome P450, putative 0.0097 0.0117 0.0707
Echinococcus multilocularis neuropeptide receptor A26 0.0887 0.1399 0.3548
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.014 0.1414
Trypanosoma brucei epsilon tubulin 0.0582 0.0905 0.5735
Echinococcus granulosus RUN 0.0071 0.0074 0.0219
Onchocerca volvulus Glucosylceramidase homolog 0.0189 0.0265 0.1693
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0288 0.0426 0.1538
Schistosoma mansoni acetylcholine receptor-related 0.0052 0.0044 0.0043
Onchocerca volvulus 0.0434 0.0663 0.4242
Leishmania major beta tubulin 0.0997 0.1578 1
Brugia malayi Steroid receptor seven-up type 2 0.0072 0.0075 0.027
Brugia malayi hypothetical protein 0.0029 0.0005 0.0017
Schistosoma mansoni amine GPCR 0.0434 0.0663 0.0662
Trypanosoma brucei zeta tubulin 0.0589 0.0915 0.5798
Brugia malayi jmjC domain containing protein 0.0195 0.0275 0.0993
Brugia malayi hypothetical protein 0.0122 0.0157 0.0564
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0017 0.0061
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0065 0.0064 0.0191
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Brugia malayi Pepsin A precursor 0.0495 0.0764 0.276
Schistosoma mansoni ran 0.0088 0.0101 0.01
Echinococcus granulosus neuropeptide FF receptor 2 0.0434 0.0663 0.1969
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0043 0.0029 0.0085
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0088 0.0101 0.0637
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.022
Loa Loa (eye worm) hypothetical protein 0.2095 0.3364 1
Plasmodium falciparum glutathione reductase 0.0046 0.0033 0.0097
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0039 0.0022 0.0064
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.014 0.1142
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0028 0.0027
Onchocerca volvulus 0.0039 0.0022 0.0138
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0088 0.0527
Loa Loa (eye worm) hypothetical protein 0.1099 0.1744 0.5185
Echinococcus granulosus pyruvate kinase 0.0074 0.0078 0.023
Loa Loa (eye worm) hypothetical protein 0.0112 0.014 0.0414
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0011 0.0016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Toxoplasma gondii isocitrate dehydrogenase 0.0065 0.0064 0.0175
Echinococcus granulosus follistatin 0.0046 0.0033 0.0096
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.002 0.0019
Leishmania major cytochrome p450-like protein 0.0071 0.0074 0.0374
Brugia malayi hypothetical protein 0.0034 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0218 0.0552
Echinococcus multilocularis tubulin alpha chain 0.0739 0.116 0.2941
Plasmodium vivax tubulin beta chain, putative 0.0997 0.1578 0.4691
Onchocerca volvulus 0.0061 0.0058 0.0366
Loa Loa (eye worm) acetylcholinesterase 1 0.0131 0.0172 0.0509
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.0281 0.0822
Plasmodium falciparum tubulin delta chain, putative 0.0252 0.0367 0.1092
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0039 0.0022 0.0064
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0075 0.027
Echinococcus granulosus peptidase Clp S14 family 0.0204 0.029 0.0859
Toxoplasma gondii tubulin, putative 0.0032 0.0011 0.0015
Echinococcus granulosus acetylcholinesterase 0.0131 0.0172 0.0509
Loa Loa (eye worm) DR-78 0.0034 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Brugia malayi jmjC domain containing protein 0.0051 0.0041 0.0145
Echinococcus multilocularis jumonji domain containing protein 0.0087 0.0099 0.0249
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0088 0.0101 0.0297
Schistosoma mansoni hypothetical protein 0.0083 0.0093 0.0092
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0434 0.0663 0.1969
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0348 0.0523 0.1892
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0434 0.0663 0.168
Schistosoma mansoni hypothetical protein 0.0093 0.011 0.0109
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0017 0.0043
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0334 0.0502 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0739 0.116 0.2941
Loa Loa (eye worm) hypothetical protein 0.0062 0.0059 0.0175
Trypanosoma cruzi zeta tubulin, putative 0.0589 0.0915 0.5784
Plasmodium falciparum pyruvate kinase 0.0074 0.0078 0.0232
Brugia malayi conserved hypotetical protein 0.0034 0.0013 0.0046
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Brugia malayi secreted modular calcium-binding protein 1 0.0046 0.0033 0.0117
Schistosoma mansoni topbp1 0.0029 0.0005 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0287 0.0424 0.1074
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0334 0.0502 0.442
Schistosoma mansoni tubulin subunit gamma 0.0583 0.0906 0.0905
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0058 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0311 0.0464 0.1377
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Echinococcus granulosus allatostatin A receptor 0.0434 0.0663 0.1969
Onchocerca volvulus 0.0034 0.0013 0.0082
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0114 0.0143 0.0515
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0253 0.037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Echinococcus multilocularis fmrfamide receptor 0.0434 0.0663 0.168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0072 0.0075 0.0222
Leishmania major beta tubulin 0.0997 0.1578 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0032 0.0031
Onchocerca volvulus 0.0305 0.0454 0.2905
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0049 0.0316
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.0083
Schistosoma mansoni neuropeptide receptor 0.0434 0.0663 0.0662
Trichomonas vaginalis pyruvate kinase, putative 0.0074 0.0078 0.0216
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.005 0.0281
Brugia malayi Tachykinin-like peptides receptor 99D 0.0434 0.0663 0.2396
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0254 0.0753
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.055 0.0853 0.2523
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Loa Loa (eye worm) tubulin beta chain 0.0997 0.1578 0.469
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.0013 0.0044
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0033 0.0117
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.0029 0.0081
Plasmodium vivax aspartyl protease, putative 0.0495 0.0764 0.227
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.0047 0.0261
Brugia malayi nuclear receptor RXR 0.0038 0.002 0.007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Trichomonas vaginalis tubulin, putative 0.0997 0.1578 0.4682
Echinococcus multilocularis geminin 0.1741 0.2788 0.7071
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0452 0.0693 0.2059
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0114 0.0143 0.0361
Schistosoma mansoni hypothetical protein 0.1244 0.198 0.198
Trypanosoma cruzi zeta tubulin, putative 0.0589 0.0915 0.5784
Mycobacterium tuberculosis Conserved protein 0.0112 0.014 0.1142
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0039 0.0022 0.0078
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0071 0.0074 0.0549
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0028 0.0082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.005 0.0148
Brugia malayi Ets-domain containing protein 0.0071 0.0074 0.0264
Echinococcus granulosus PHD finger protein rhinoceros 0.0062 0.0059 0.0175
Schistosoma mansoni GTP-binding protein alpha subunit 0.0039 0.0022 0.0022
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0434 0.0663 0.168
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0276 0.0406 0.1207
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0071 0.0074 0.0438
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0058 0.0336
Echinococcus granulosus tm gpcr rhodopsin 0.0434 0.0663 0.1969
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0051 0.0041 0.0258
Schistosoma mansoni sodium/chloride dependent transporter 0.0253 0.037 0.0369
Brugia malayi sulfakinin receptor protein 0.0434 0.0663 0.2396
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0088 0.0527
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0001 0.0004
Onchocerca volvulus 0.0043 0.0028 0.0176
Loa Loa (eye worm) ACC-1 protein 0.0114 0.0143 0.0424
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0049 0.0143
Echinococcus granulosus phd:f box containing protein 0.0051 0.0041 0.0119
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0049
Loa Loa (eye worm) hypothetical protein 0.0112 0.014 0.0414
Echinococcus granulosus nAChR subunit 0.0061 0.0058 0.017
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0028 0.0082
Loa Loa (eye worm) tubulin beta-4 chain 0.0997 0.1578 0.469
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0107 0.0132 0.2557
Leishmania major beta tubulin 0.0997 0.1578 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1128 0.1791 0.5324
Schistosoma mansoni importin beta-1 0.0119 0.0152 0.0151
Echinococcus granulosus TGF beta signal transducer SmadC 0.0058 0.0053 0.0156
Echinococcus multilocularis survival motor neuron protein 1 0.071 0.1112 0.282
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0013 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.014 0.0414
Loa Loa (eye worm) fli-1 protein 0.0215 0.0308 0.0916
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0434 0.0663 0.0662
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0075 0.027
Plasmodium falciparum pyruvate kinase 2 0.0038 0.002 0.0059
Onchocerca volvulus 0.0434 0.0663 0.4242
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0073 0.0215
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0071 0.0074 0.0725
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0058 0.0146
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0434 0.0663 0.1969
Onchocerca volvulus 0.0092 0.0109 0.0691
Brugia malayi hypothetical protein 0.0034 0.0013 0.0046
Brugia malayi Latrophilin receptor protein 2 0.0348 0.0523 0.1892
Brugia malayi Tubulin alpha-2 chain 0.0739 0.116 0.4195
Schistosoma mansoni hypothetical protein 0.1741 0.2788 0.2788
Brugia malayi Pax transcription activation domain interacting protein 0.0029 0.0005 0.0017
Leishmania major beta tubulin 0.0997 0.1578 1
Plasmodium vivax JmjC domain containing protein 0.0051 0.0041 0.0121
Loa Loa (eye worm) tubulin beta-1 chain 0.0997 0.1578 0.469
Giardia lamblia NADH oxidase lateral transfer candidate 0.0046 0.0033 0.0172
Schistosoma mansoni hypothetical protein 0.0062 0.0059 0.0059
Echinococcus granulosus agrin 0.0046 0.0033 0.0096
Trypanosoma brucei beta tubulin 0.055 0.0853 0.5404
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0075 0.0075
Echinococcus multilocularis muscleblind protein 1 0.0144 0.0193 0.0487
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0039 0.0022 0.0078
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0065 0.0064 0.0063
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0061 0.0058 0.0057
Trichomonas vaginalis tubulin gamma chain, putative 0.0582 0.0905 0.2678
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0071 0.0074 0.0549
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Schistosoma mansoni ap endonuclease 0.0056 0.005 0.0049
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0072 0.0075 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0072 0.0075 0.0222
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0028 0.007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Brugia malayi nuclear receptor NHR-67 0.0034 0.0013 0.0046
Loa Loa (eye worm) cytochrome P450 family protein 0.0223 0.0321 0.0953
Leishmania major beta tubulin 0.0997 0.1578 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0997 0.1578 0.4682
Echinococcus multilocularis fmrfamide receptor 0.0434 0.0663 0.168
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0007 0.002
Trypanosoma brucei epsilon tubulin 0.055 0.0853 0.5404
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0046 0.0033 0.0081
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0029 0.0005 0.00000086864
Echinococcus granulosus lysine specific demethylase 6a 0.0051 0.0041 0.0119
Schistosoma mansoni hypothetical protein 0.0434 0.0663 0.0662
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0301 0.0447 0.3926
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0046 0.0033 0.0032
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0071 0.0074 0.0725
Plasmodium vivax plasmepsin IV, putative 0.2095 0.3364 1
Plasmodium vivax tubulin alpha chain, putative 0.0739 0.116 0.3448
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0041 0.0119
Brugia malayi Pyruvate kinase, muscle isozyme 0.0074 0.0078 0.028
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Toxoplasma gondii beta tubulin 0.0997 0.1578 0.4682
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0434 0.0663 0.0662
Trichomonas vaginalis esterase, putative 0.0112 0.014 0.04
Echinococcus granulosus mothers against decapentaplegic 5 0.0058 0.0053 0.0156
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0042 0.0122
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0042 0.0263
Trypanosoma brucei alpha tubulin 0.0739 0.116 0.7351
Loa Loa (eye worm) LGC-31 protein 0.0114 0.0143 0.0424
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0028 0.007
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0071 0.0074 0.0725
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0071 0.0074 0.0549
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.002 0.0042
Echinococcus granulosus tubulin epsilon chain 0.0582 0.0905 0.2689
Brugia malayi jmjC domain containing protein 0.0318 0.0476 0.1719
Onchocerca volvulus Bile acid receptor homolog 0.0072 0.0075 0.0478
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0114 0.0143 0.0423
Giardia lamblia Beta tubulin 0.0997 0.1578 1
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0056 0.0049 0.0143
Plasmodium falciparum thioredoxin reductase 0.0046 0.0033 0.0097
Echinococcus multilocularis neuropeptide Y receptor 0.0434 0.0663 0.168
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.014 0.1142
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0049 0.0455
Leishmania major gamma-tubulin 0.0583 0.0906 0.5696
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0071 0.0074 0.0725
Schistosoma mansoni hypothetical protein 0.0348 0.0523 0.0523
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0016 0.0067
Brugia malayi ecdysone receptor 0.0034 0.0013 0.0046
Onchocerca volvulus 0.0987 0.1562 1
Trichomonas vaginalis tubulin beta chain, putative 0.0299 0.0444 0.1304
Schistosoma mansoni hypothetical protein 0.0062 0.006 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0915 0.1446 0.1445
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0434 0.0663 0.168
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0016 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Onchocerca volvulus 0.0434 0.0663 0.4242
Schistosoma mansoni alpha tubulin 0.0739 0.116 0.1159
Schistosoma mansoni alpha glucosidase 0.0035 0.0016 0.0015
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0114 0.0143 0.0515
Loa Loa (eye worm) steroid hormone receptor 0.0072 0.0075 0.0222
Loa Loa (eye worm) hypothetical protein 0.0131 0.0172 0.0509
Plasmodium falciparum ataxin-2 like protein, putative 0.0208 0.0297 0.0882
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0046 0.0033 0.0106
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.014 0.1142
Mycobacterium ulcerans dehydrogenase 0.0043 0.0029 0.0242
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0069 0.0204
Loa Loa (eye worm) hypothetical protein 0.0201 0.0284 0.0844
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.0123
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0311 0.0464 0.9231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0028 0.0068
Schistosoma mansoni chromosome transmission fidelity factor 0.0029 0.0005 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.0434 0.0663 0.1969
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0016 0.0055
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0058 0.0271
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0028 0.007
Brugia malayi Isocitrate dehydrogenase 0.0065 0.0064 0.023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0075 0.027
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0068 0.043
Loa Loa (eye worm) CYP4Cod1 0.0097 0.0117 0.0345
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0039 0.0022 0.0022
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0114 0.0143 0.0424
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 1
Schistosoma mansoni coup transcription factor 0.0072 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Schistosoma mansoni microtubule-associated protein tau 0.1364 0.2175 0.2175
Schistosoma mansoni nuclear receptor 0.0034 0.0013 0.0013
Brugia malayi Cytochrome P450 family protein 0.0097 0.0117 0.0419
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0434 0.0663 0.1969
Brugia malayi Eukaryotic aspartyl protease family protein 0.0495 0.0764 0.276
Loa Loa (eye worm) hypothetical protein 0.0046 0.0033 0.0097
Loa Loa (eye worm) beta-tubulin 0.0997 0.1578 0.469
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0033 0.0591
Trypanosoma cruzi epsilon tubulin, putative 0.0582 0.0905 0.572
Echinococcus granulosus g protein coupled receptor 0.0434 0.0663 0.1969
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0062 0.0059 0.0059
Schistosoma mansoni neuropeptide receptor 0.0434 0.0663 0.0662
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0065 0.0064 0.0191
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 0.4823
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Echinococcus granulosus fmrfamide receptor 0.0434 0.0663 0.1969
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0016 0.0067
Brugia malayi Tubulin beta chain 0.0252 0.0367 0.1327
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0058 0.0146
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0028 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0188 0.0265 0.0264
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0434 0.0663 0.168
Echinococcus multilocularis tubulin alpha chain 0.0739 0.116 0.2941
Trypanosoma brucei beta tubulin 0.0997 0.1578 1
Plasmodium falciparum plasmepsin V 0.0495 0.0764 0.227
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0348 0.0523 0.1326
Schistosoma mansoni jumonji/arid domain-containing protein 0.0195 0.0275 0.0275
Schistosoma mansoni hypothetical protein 0.0348 0.0523 0.0523
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Trypanosoma brucei alpha tubulin 0.0739 0.116 0.7351
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0051 0.0041 0.0224
Echinococcus multilocularis dnaJ subfamily B 0.1244 0.198 0.5022
Trichomonas vaginalis tubulin alpha chain, putative 0.055 0.0853 0.2523
Loa Loa (eye worm) hypothetical protein 0.0144 0.0193 0.0572
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0059 0.016
Onchocerca volvulus 0.0051 0.0042 0.0263
Loa Loa (eye worm) hypothetical protein 0.1727 0.2764 0.8217
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Toxoplasma gondii beta-tubulin, putative 0.0997 0.1578 0.4682
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1099 0.1744 0.5185
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Loa Loa (eye worm) BEN-1 protein 0.0997 0.1578 0.469
Brugia malayi hypothetical protein 0.0071 0.0073 0.0262
Mycobacterium ulcerans hypothetical protein 0.0112 0.014 0.1414
Brugia malayi tubulin alpha-2 chain 0.0739 0.116 0.4195
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0071 0.0074 0.0725
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0049
Loa Loa (eye worm) aspartic protease BmAsp-2 0.2095 0.3364 1
Echinococcus multilocularis pyruvate kinase 0.0038 0.002 0.0048
Schistosoma mansoni histamine h1 receptor 0.0434 0.0663 0.0662
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0071 0.0074 0.0725
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0495 0.0764 0.2257
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0067 0.0068 0.02
Brugia malayi G protein-coupled receptor F59B2.13 0.0434 0.0663 0.2396
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0088 0.0101 0.0604
Mycobacterium ulcerans beta-lactamase 0.0112 0.014 0.1414
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0172 0.0171
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0042 0.0041
Echinococcus multilocularis importin subunit beta 1 0.0119 0.0152 0.0383
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Brugia malayi MH1 domain containing protein 0.0058 0.0053 0.019
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0301 0.0447 0.3926
Schistosoma mansoni pyruvate kinase 0.0074 0.0078 0.0077
Echinococcus granulosus tubulin alpha 1C chain 0.0739 0.116 0.3447
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0072 0.0075 0.0189
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0039 0.0022 0.0055
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0039 0.0022 0.005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0037 0.0131
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0028 0.0082
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0015
Schistosoma mansoni rab6-interacting 0.0071 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trypanosoma brucei alpha tubulin 0.0739 0.116 0.7351
Plasmodium vivax aspartyl protease, putative 0.0495 0.0764 0.227
Plasmodium falciparum glutathione reductase 0.0132 0.0173 0.0513
Loa Loa (eye worm) hypothetical protein 0.1246 0.1984 0.5896
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0426 0.1251
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0016 0.0031
Schistosoma mansoni hypothetical protein 0.0083 0.0093 0.0092
Trypanosoma cruzi epsilon tubulin, putative 0.0582 0.0905 0.572
Entamoeba histolytica hypothetical protein 0.0071 0.0073 0.0429
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0039 0.0022 0.0022
Echinococcus granulosus alpha 1A adrenergic receptor 0.0434 0.0663 0.1969
Echinococcus granulosus tubulin beta 4A class IVa 0.0997 0.1578 0.469
Plasmodium falciparum transporter, putative 0.0043 0.0028 0.0084
Toxoplasma gondii histone lysine methyltransferase SET1 0.0176 0.0244 0.0711
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0037 0.033
Brugia malayi AKH receptor 0.0434 0.0663 0.2396
Echinococcus granulosus FTZ F1 alpha 0.0072 0.0075 0.0222
Leishmania major hypothetical protein, conserved 0.0112 0.014 0.0793
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0069 0.0248
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0189 0.3704
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0288 0.0426 0.1264
Schistosoma mansoni tar DNA-binding protein 0.0452 0.0693 0.0692
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0114 0.0143 0.0423
Entamoeba histolytica Ran family GTPase 0.0088 0.0101 0.0604
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0114 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0013 0.0046
Loa Loa (eye worm) GABA receptor subunit 0.0061 0.0058 0.017
Brugia malayi nuclear receptor NHR-88 0.0072 0.0075 0.027
Brugia malayi hypothetical protein 0.071 0.1112 0.4023
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0033 0.0172
Echinococcus granulosus pyruvate kinase 0.0038 0.002 0.0057
Plasmodium falciparum alpha tubulin 2 0.0739 0.116 0.3448
Brugia malayi ecdysteroid receptor 0.0072 0.0075 0.027
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0051 0.0041 0.004
Toxoplasma gondii thioredoxin reductase 0.0132 0.0173 0.0498
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0075 0.027
Brugia malayi nuclear receptor RXR 0.0034 0.0013 0.0046
Trypanosoma brucei unspecified product 0.0026 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0119
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0028 0.007
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0072 0.0075 0.027
Onchocerca volvulus 0.0087 0.01 0.0638
Echinococcus granulosus Tubulin alpha 1 chain 0.0739 0.116 0.3447
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0042 0.0041
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0071 0.0074 0.0725
Echinococcus granulosus histone lysine methyltransferase setb 0.0089 0.0104 0.0306
Onchocerca volvulus 0.0434 0.0663 0.4242
Plasmodium vivax pyruvate kinase 2, putative 0.0038 0.002 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0252 0.0367 0.1078
Onchocerca volvulus 0.0114 0.0143 0.0912
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Brugia malayi putative neuropeptide receptor 0.0434 0.0663 0.2396
Brugia malayi MH2 domain containing protein 0.0058 0.0053 0.019
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0016 0.0031
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.0013 0.0013
Brugia malayi Cytochrome P450 family protein 0.0071 0.0074 0.0267
Giardia lamblia Gamma tubulin 0.0583 0.0906 0.5725
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.014 0.1142
Loa Loa (eye worm) solute carrier family 6 member 4 0.0253 0.037 0.1097
Onchocerca volvulus 0.0114 0.0143 0.0912
Echinococcus granulosus jumonji domain containing protein 0.0087 0.0099 0.0292
Schistosoma mansoni hypothetical protein 0.1269 0.2022 0.2021
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.0024 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0071 0.0074 0.0549
Brugia malayi hypothetical protein 0.0043 0.0029 0.0101
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.0013 0.0039
Brugia malayi isocitrate dehydrogenase 0.0065 0.0064 0.023
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0037 0.033
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0434 0.0663 0.0662
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0058 0.0171
Loa Loa (eye worm) thioredoxin reductase 0.0132 0.0173 0.0512
Onchocerca volvulus 0.0082 0.0091 0.058
Brugia malayi hypothetical protein 0.0052 0.0044 0.0155
Loa Loa (eye worm) MBCTL1 0.0058 0.0053 0.0157
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0107 0.0132 0.277
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.0029 0.0181
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.0281 0.0822
Toxoplasma gondii hypothetical protein 0.0107 0.0132 0.0378
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0017 0.0029
Onchocerca volvulus 0.0145 0.0194 0.1237
Schistosoma mansoni tubulin subunit beta 0.0997 0.1578 0.1577
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.005 0.0132
Echinococcus multilocularis Tubulin beta 2C chain 0.0997 0.1578 0.4001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0046 0.0033 0.0206
Loa Loa (eye worm) hypothetical protein 0.0119 0.0152 0.0449
Schistosoma mansoni neuropeptide F-like receptor 0.0434 0.0663 0.0662
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0071 0.0074 0.0725
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0029 0.0134
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0434 0.0663 0.168
Leishmania major zeta tubulin, putative 0.0589 0.0915 0.5756
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0029 0.0028
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.0013 0.0046
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0028 0.007
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0074 0.0078 0.0582
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0431 0.2707
Trypanosoma brucei cytochrome P450, putative 0.0097 0.0117 0.0739
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0434 0.0663 0.168
Onchocerca volvulus 0.0112 0.014 0.0891
Onchocerca volvulus 0.0112 0.014 0.0891
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0088 0.0101 0.0361
Brugia malayi DKFZp564C0469 protein 0.0029 0.0005 0.0017
Plasmodium vivax aspartyl proteinase, putative 0.0495 0.0764 0.227
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0028 0.0027
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0071 0.0074 0.0725
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0042 0.0122
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0107 0.0132 0.0394
Schistosoma mansoni cytochrome P450 0.0071 0.0074 0.0074
Echinococcus multilocularis protein patched 0.0086 0.0098 0.0247
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0104 0.0103
Brugia malayi Melatonin receptor type 1A 0.0434 0.0663 0.2396
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0054 0.0047 0.0261
Trypanosoma brucei C-14 sterol reductase, putative 0.0098 0.0118 0.0749
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0114 0.0143 0.0515
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0037 0.0209
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0016 0.0031
Brugia malayi Calcitonin receptor-like protein seb-1 0.1099 0.1744 0.6309
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0075 0.0075
Schistosoma mansoni nAChR subunit 0.0052 0.0044 0.0043
Schistosoma mansoni hypothetical protein 0.0083 0.0093 0.0092
Toxoplasma gondii ABC1 family protein 0.0112 0.014 0.04
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0065 0.0064 0.0161
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0067 0.0068 0.017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Trypanosoma cruzi C-14 sterol reductase, putative 0.0098 0.0118 0.0717
Schistosoma mansoni tubulin subunit beta 0.0997 0.1578 0.1577
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0093 0.011 0.0325
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 1
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Brugia malayi Pax transcription factor protein 2 0.0987 0.1562 0.5649
Loa Loa (eye worm) transcription factor SMAD2 0.0856 0.135 0.4012
Brugia malayi follicle stimulating hormone receptor 0.1128 0.1791 0.6479
Echinococcus granulosus beta tubulin 0.0997 0.1578 0.469
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0067 0.0068 0.017
Schistosoma mansoni single-minded 0.0059 0.0054 0.0053
Schistosoma mansoni nuclear receptor 0.0034 0.0013 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0023 0.0022
Mycobacterium leprae Conserved hypothetical protein 0.0071 0.0074 0.1388
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0046 0.0033 0.0115
Brugia malayi hypothetical protein 0.0052 0.0044 0.0155
Echinococcus multilocularis dro:myosuppressin receptor 0.0434 0.0663 0.168
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0052 0.0044 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0072 0.0075 0.0222
Echinococcus granulosus sterol regulatory element binding protein 0.0086 0.0098 0.029
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0061 0.0058 0.0207
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0114 0.0143 0.0423
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0068 0.0243
Loa Loa (eye worm) hypothetical protein 0.0122 0.0157 0.0464
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.0163 0.0468
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0037 0.0131
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0049 0.021
Brugia malayi RNA binding protein 0.0452 0.0693 0.2505
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Loa Loa (eye worm) hypothetical protein 0.0305 0.0454 0.1349
Toxoplasma gondii exonuclease III APE 0.0056 0.005 0.0132
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0495 0.0764 0.2268
Echinococcus granulosus sex peptide receptor 0.0434 0.0663 0.1969
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0915 0.1446 0.1445
Echinococcus multilocularis ecdysone induced protein 78C 0.0072 0.0075 0.0189
Entamoeba histolytica pyruvate kinase, putative 0.0051 0.0042 0.0231
Echinococcus granulosus Tubulin beta 2C chain 0.0997 0.1578 0.469
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0297 0.0441 0.1117
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0114 0.0143 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0047 0.0122
Brugia malayi neuropeptide F receptor 0.0434 0.0663 0.2396
Echinococcus granulosus Protein patched homolog 1 0.0086 0.0098 0.029
Echinococcus multilocularis beta tubulin 0.0997 0.1578 0.4001
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0064
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0068 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0072 0.0075 0.027
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.0058
Schistosoma mansoni cathepsin D (A01 family) 0.6178 1 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0051 0.0041 0.0105
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0318 0.0476 0.1413
Brugia malayi Cytochrome P450 family protein 0.0223 0.0321 0.1159
Echinococcus granulosus nibrin 0.0029 0.0005 0.0014
Leishmania major C-8 sterol isomerase-like protein 0.0713 0.1116 0.7045
Echinococcus multilocularis tubulin subunit beta 0.0997 0.1578 0.4001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0101 0.0298
Plasmodium vivax pyruvate kinase, putative 0.0074 0.0078 0.0232
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0039 0.0022 0.005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.0013 0.0013
Echinococcus multilocularis Polycystic kidney disease protein 0.0071 0.0074 0.0187
Echinococcus granulosus tubulin subunit TubB 0.0739 0.116 0.3447
Echinococcus multilocularis microtubule associated protein 2 0.1364 0.2175 0.5516
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0114 0.0143 0.0142
Schistosoma mansoni hypothetical protein 0.0083 0.0093 0.0092
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0016 0.0067
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.0431 0.2707
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0114 0.0143 0.0361
Echinococcus multilocularis lamin b receptor 0.0098 0.0118 0.0298
Trichomonas vaginalis tubulin, putative 0.0299 0.0444 0.1304
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0318 0.0476 0.1205
Trypanosoma brucei alpha tubulin 0.0739 0.116 0.7351
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0028 0.0494
Brugia malayi MH1 domain containing protein 0.0058 0.0053 0.019
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0039 0.0022 0.0078
Trypanosoma brucei zeta tubulin, putative 0.0589 0.0915 0.5798
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0089 0.0104 0.0103
Mycobacterium tuberculosis Probable dehydrogenase 0.0301 0.0447 0.3926
Schistosoma mansoni neuropeptide receptor 0.0434 0.0663 0.0662
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0441 0.0675 0.1993
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.0013 0.0039
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0145 0.0194 0.0698
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0075 0.0222
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0311 0.0464 0.1364
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0204 0.0289 0.0289
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0096 0.0115 0.0326
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0046 0.0033 0.0097
Trypanosoma brucei beta tubulin 0.0997 0.1578 1
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0189 0.159
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0058 0.0172
Loa Loa (eye worm) alpha-tubulin 0.0739 0.116 0.3447
Loa Loa (eye worm) isocitrate dehydrogenase 0.0065 0.0064 0.0189
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0039 0.0022 0.0022
Onchocerca volvulus 0.0071 0.0074 0.0472
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0172
Plasmodium falciparum tubulin gamma chain 0.0583 0.0906 0.2693
Plasmodium vivax ataxin-2 like protein, putative 0.0208 0.0297 0.0882
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0114 0.0143 0.0515
Mycobacterium leprae putative cytochrome p450 0.0071 0.0074 0.1388
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.002 0.0054
Plasmodium vivax thioredoxin reductase, putative 0.0132 0.0173 0.0513
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0029 0.0005 0.00000040672
Mycobacterium leprae Probable pyruvate kinase PykA 0.0074 0.0078 0.146
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.002 0.0019
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0434 0.0663 0.2396
Echinococcus multilocularis Tubulin beta 2C chain 0.0997 0.1578 0.4001
Loa Loa (eye worm) hypothetical protein 0.0253 0.037 0.1097
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0017 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0114 0.0143 0.0361
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0039 0.0022 0.0055
Leishmania major C-14 sterol reductase, putative 0.0098 0.0118 0.0655
Loa Loa (eye worm) hypothetical protein 0.0046 0.0033 0.0097
Echinococcus multilocularis agrin 0.0046 0.0033 0.0082
Brugia malayi PAS domain containing protein 0.0059 0.0054 0.0192
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0065 0.0064 0.0373
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0042 0.0104
Brugia malayi hypothetical protein 0.0495 0.0764 0.276
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.002 0.0058
Loa Loa (eye worm) tubulin alpha chain 0.0739 0.116 0.3447
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0014 0.0024
Toxoplasma gondii ATPase, AAA family protein 0.0029 0.0005 0.00000040672
Mycobacterium tuberculosis Conserved protein 0.0112 0.014 0.1142
Loa Loa (eye worm) hypothetical protein 0.0112 0.014 0.0414
Echinococcus granulosus beta tubulin 0.0997 0.1578 0.469
Echinococcus multilocularis JmjC domain containing protein 4 0.0051 0.0041 0.0101
Schistosoma mansoni biogenic amine receptor 0.0434 0.0663 0.0662
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0029 0.0005 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0208 0.0297 0.1852
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0043 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Plasmodium falciparum LCCL domain-containing protein 0.0071 0.0074 0.0221
Toxoplasma gondii protease inhibitor PI2 0.0046 0.0033 0.0082
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Giardia lamblia Beta tubulin 0.0997 0.1578 1
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0039 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0015
Trichomonas vaginalis importin beta-1, putative 0.0096 0.0115 0.0326
Echinococcus multilocularis phd:f box containing protein 0.0051 0.0041 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0071 0.0074 0.0549
Brugia malayi MH1 domain containing protein 0.0032 0.0011 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Trichomonas vaginalis tubulin epsilon chain, putative 0.0997 0.1578 0.4682
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0088 0.0527
Brugia malayi tailless protein 0.0034 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Echinococcus multilocularis jumonji domain containing 1A 0.0051 0.0041 0.0101
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0086 0.0098 0.029
Brugia malayi latrophilin 2 splice variant baaae 0.0751 0.1179 0.4265
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0028 0.0027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0033 0.0172
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0915 0.1446 0.3667
Schistosoma mansoni memapsin-2 (A01 family) 0.0495 0.0764 0.0763
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0039 0.0022 0.0055
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0091 0.0327
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0072 0.0075 0.0075
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0039 0.0022 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0029 0.0085
Loa Loa (eye worm) histone methyltransferase 0.003 0.0007 0.0021
Loa Loa (eye worm) RNA binding protein 0.0452 0.0693 0.2059
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0058 0.0053 0.0133
Echinococcus multilocularis expressed protein 0.0039 0.0022 0.0055
Echinococcus granulosus orexin receptor type 2 0.0434 0.0663 0.1969
Echinococcus multilocularis serotonin receptor 0.0434 0.0663 0.168
Plasmodium vivax aspartyl protease, putative 0.0495 0.0764 0.227
Schistosoma mansoni biogenic amine receptor 0.0434 0.0663 0.0662
Schistosoma mansoni loxhd1 0.0071 0.0074 0.0074
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.014 0.04
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Trichomonas vaginalis tubulin epsilon chain, putative 0.0739 0.116 0.3438
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0088 0.0527
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0039 0.0022 0.005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0067
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0114 0.0143 0.0515
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0039 0.0022 0.0078
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0434 0.0663 0.0662
Plasmodium vivax amine transporter, putative 0.0043 0.0028 0.0084
Loa Loa (eye worm) G-protein coupled receptor 0.0434 0.0663 0.1969
Trichomonas vaginalis tubulin, putative 0.0299 0.0444 0.1304
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Brugia malayi Carboxylesterase family protein 0.0131 0.0172 0.0619
Mycobacterium tuberculosis Conserved protein 0.0112 0.014 0.1142
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0172
Loa Loa (eye worm) tubulin alpha-2 chain 0.0739 0.116 0.3447
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0114 0.0143 0.0142
Loa Loa (eye worm) jmjC domain-containing protein 0.0195 0.0275 0.0817
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0039 0.0022 0.0078
Schistosoma mansoni Lamin B receptor (ERG24) 0.0098 0.0118 0.0118
Trichomonas vaginalis tubulin epsilon chain, putative 0.0739 0.116 0.3438
Echinococcus multilocularis tubulin alpha 0.055 0.0853 0.2161
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.01 0.0296
Trypanosoma brucei alpha tubulin, putative 0.0299 0.0444 0.2811
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0049
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0065 0.0064 0.0406
Brugia malayi prostaglandin transporter 0.0067 0.0068 0.0243
Trypanosoma cruzi sterol C-24 reductase, putative 0.0098 0.0118 0.0717
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.014 0.0414
Brugia malayi glutathione reductase 0.0132 0.0173 0.0622
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0172
Echinococcus multilocularis tubulin alpha chain 0.0739 0.116 0.2941
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Brugia malayi Thioredoxin reductase 0.0132 0.0173 0.0622
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0016 0.0067
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0074 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0047 0.0122
Echinococcus multilocularis X box binding protein 1 0.0287 0.0424 0.1075
Echinococcus multilocularis peptidase Clp (S14 family) 0.0204 0.029 0.0733
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0016 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0082 0.0091 0.027
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0114 0.0143 0.0423
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0053 0.0156
Toxoplasma gondii pyruvate kinase PyK1 0.0074 0.0078 0.0216
Echinococcus granulosus tubulin alpha chain 0.0739 0.116 0.3447
Schistosoma mansoni hypothetical protein 0.1741 0.2788 0.2788
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.004 0.0142
Brugia malayi acetyltransferase, GNAT family protein 0.0297 0.0441 0.1593
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0056 0.0049 0.0122
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0068 0.043
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0088 0.0101 0.0283
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0052 0.0044 0.0109
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0046 0.0033 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0014 0.0024
Brugia malayi hypothetical protein 0.0052 0.0044 0.0155
Onchocerca volvulus 0.0071 0.0074 0.0472
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0075 0.0222
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0434 0.0663 0.0662
Schistosoma mansoni acetylcholine receptor subunit beta 0.0052 0.0044 0.0043
Trypanosoma brucei tubulin delta chain 0.0453 0.0695 0.4404
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0071 0.0074 0.0549
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0434 0.0663 0.1969
Trichomonas vaginalis tubulin beta chain, putative 0.0739 0.116 0.3438
Echinococcus multilocularis Tubulin beta 2C chain 0.0997 0.1578 0.4001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0015
Entamoeba histolytica hypothetical protein 0.0071 0.0073 0.0429
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.014 0.0854
Loa Loa (eye worm) hypothetical protein 0.0046 0.0033 0.0097
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0017 0.025
Plasmodium falciparum importin beta, putative 0.0119 0.0152 0.0451
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.002 0.009
Brugia malayi MAP kinase sur-1 0.0062 0.0058 0.0209
Loa Loa (eye worm) serotonin transporter b 0.0253 0.037 0.1097
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0029 0.0083
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0069 0.0068
Giardia lamblia Epsilon tubulin 0.0284 0.042 0.2634
Loa Loa (eye worm) hypothetical protein 0.0751 0.1179 0.3505
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0028 0.0099
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.057 0.0885 0.7892
Trypanosoma brucei unspecified product 0.0038 0.002 0.0125
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0099
Echinococcus multilocularis glycine receptor subunit beta 0.0114 0.0143 0.0361
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0189 0.1935
Loa Loa (eye worm) hypothetical protein 0.0364 0.055 0.1634
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0114 0.0143 0.0423
Schistosoma mansoni zinc finger protein 0.0034 0.0013 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0059 0.0175
Echinococcus granulosus Tubulin beta 2C chain 0.0997 0.1578 0.469
Echinococcus granulosus G protein coupled receptor 139 0.0434 0.0663 0.1969
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0039 0.0022 0.0078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Echinococcus multilocularis lysine specific demethylase 6a 0.0051 0.0041 0.0101
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0114 0.0143 0.0515
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Brugia malayi hypothetical protein 0.0038 0.002 0.007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0007 0.0017
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Schistosoma mansoni tubulin subunit alpha 0.0739 0.116 0.1159
Leishmania major DNA polymerase kappa, putative 0.0038 0.002 0.0024
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0028 0.0082
Brugia malayi hypothetical protein 0.0029 0.0005 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0114 0.0143 0.0515
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0426 0.1251
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0088 0.0263
Plasmodium falciparum replication factor C subunit 1, putative 0.0029 0.0005 0.0016
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0488 0.0751 0.2219
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0043 0.0029 0.0071
Loa Loa (eye worm) cytochrome P450 0.0071 0.0074 0.022
Onchocerca volvulus 0.0299 0.0444 0.2837
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0033 0.0097
Brugia malayi beta-lactamase family protein 0.0112 0.014 0.0503
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0064
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0016 0.0046
Brugia malayi Pyruvate kinase, M2 isozyme 0.0074 0.0078 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Onchocerca volvulus 0.0434 0.0663 0.4242
Onchocerca volvulus Pyruvate kinase homolog 0.0074 0.0078 0.0495
Trichomonas vaginalis pyruvate kinase, putative 0.0074 0.0078 0.0216
Onchocerca volvulus 0.0052 0.0044 0.0274
Brugia malayi Tubulin alpha chain 0.0252 0.0367 0.1327
Trypanosoma cruzi importin beta-1 subunit, putative 0.0096 0.0115 0.0696
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.002 0.015
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0052 0.0044 0.0128
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0434 0.0663 0.168
Brugia malayi RE15519p 0.0434 0.0663 0.2396
Plasmodium falciparum plasmepsin I 0.2095 0.3364 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0434 0.0663 0.168
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0348 0.0523 0.1326
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0039 0.0022 0.0064
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.0047 0.0295
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0071 0.0074 0.0549
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0099
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0301 0.0447 0.3926
Echinococcus granulosus smad 0.0058 0.0053 0.0156
Schistosoma mansoni hypothetical protein 0.0348 0.0523 0.0523
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0915 0.1446 0.4297
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0052 0.0044 0.0127
Brugia malayi beta-tubulin, identical 0.0997 0.1578 0.5707
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0029 0.0005 0.0035
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0013 0.0038
Loa Loa (eye worm) ACC-1 protein 0.0114 0.0143 0.0424
Echinococcus multilocularis GPCR, family 2 0.0348 0.0523 0.1326
Trypanosoma brucei unspecified product 0.0026 0.0001 0.0004
Echinococcus granulosus Niemann Pick C1 protein 0.0287 0.0424 0.1259
Echinococcus multilocularis acetylcholinesterase 0.0131 0.0172 0.0434
Echinococcus multilocularis cpg binding protein 0.0092 0.0108 0.0273
Schistosoma mansoni lipoxygenase 0.0276 0.0406 0.0406
Schistosoma mansoni nAChR subunit 0.0052 0.0044 0.0043
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.002 0.0125
Echinococcus granulosus serotonin receptor 0.0434 0.0663 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Onchocerca volvulus 0.0039 0.0022 0.0138
Schistosoma mansoni hypothetical protein 0.0323 0.0484 0.0483
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.002 0.009
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0088 0.0101 0.0253
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0039 0.0022 0.0064
Onchocerca volvulus 0.0043 0.0028 0.0176
Echinococcus granulosus tar DNA binding protein 0.0452 0.0693 0.2058
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 0.4823
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0028 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0071 0.0074 0.0549
Echinococcus granulosus tubulin alpha 0.055 0.0853 0.2533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0028 0.0068
Plasmodium falciparum tubulin epsilon chain, putative 0.0582 0.0905 0.269
Toxoplasma gondii HEAT repeat-containing protein 0.0119 0.0152 0.0435
Echinococcus multilocularis Tubulin beta 2C chain 0.0997 0.1578 0.4001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0114 0.0143 0.0361
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0434 0.0663 0.0662
Onchocerca volvulus 0.0434 0.0663 0.4242
Echinococcus granulosus cytochrome P450 2K1 0.0071 0.0074 0.0219
Echinococcus granulosus glutamate NMDA receptor subunit 0.0061 0.0057 0.0166
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.0083
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0046 0.0033 0.0285
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0065 0.0064 0.0456
Schistosoma mansoni jumonji domain containing protein 0.0051 0.0041 0.004
Brugia malayi beta-lactamase 0.0112 0.014 0.0503
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0033 0.0082
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0434 0.0663 0.0662
Brugia malayi nuclear hormone receptor 0.0034 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Onchocerca volvulus 0.0061 0.0058 0.0366
Leishmania major epsilon tubulin, putative 0.0582 0.0905 0.5691
Loa Loa (eye worm) hypothetical protein 0.008 0.0088 0.0261
Brugia malayi hypothetical protein 0.0039 0.0022 0.0078
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.0047 0.0261
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0078 0.023
Loa Loa (eye worm) jmjC domain-containing protein 0.0128 0.0167 0.0495
Toxoplasma gondii pyruvate kinase PyKII 0.0038 0.002 0.0042
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0046 0.0033 0.0285
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0065 0.0064 0.0406
Trypanosoma brucei pyruvate kinase 1 0.0074 0.0078 0.0494
Schistosoma mansoni hypothetical protein 0.0751 0.1179 0.1179
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0037 0.033
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Echinococcus multilocularis neuropeptide receptor 0.0434 0.0663 0.168
Echinococcus granulosus neuropeptide Y receptor 0.0434 0.0663 0.1969
Schistosoma mansoni opsin-like receptor 0.0434 0.0663 0.0662
Echinococcus multilocularis carboxylesterase 5A 0.0131 0.0172 0.0434
Brugia malayi hypothetical protein 0.0495 0.0764 0.276
Brugia malayi Cation transporter family protein 0.0114 0.0143 0.0515
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0072 0.0075 0.0075
Echinococcus granulosus dro:myosuppressin receptor 0.0434 0.0663 0.1969
Echinococcus granulosus dnaJ subfamily B 0.1244 0.198 0.5886
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0058 0.0336
Schistosoma mansoni tar DNA-binding protein 0.0452 0.0693 0.0692
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0114 0.0143 0.0361
Schistosoma mansoni phosphatidylserine receptor 0.0051 0.0041 0.004
Entamoeba histolytica tubulin family protein 0.0997 0.1578 1
Schistosoma mansoni pyruvate kinase 0.0038 0.002 0.0019
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0046 0.0033 0.0097
Trypanosoma brucei protein kinase, putative 0.0062 0.0058 0.0369
Echinococcus multilocularis nAChR subunit 0.0114 0.0143 0.0361
Echinococcus multilocularis G protein coupled receptor 139 0.0434 0.0663 0.168
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0029 0.0083
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.005 0.0216
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0434 0.0663 0.1969
Schistosoma mansoni cpg binding protein 0.0092 0.0108 0.0108
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0042 0.0104
Echinococcus granulosus peptide allatostatin:somatostatin 0.0434 0.0663 0.1969
Plasmodium falciparum JmjC domain-containing protein, putative 0.0051 0.0041 0.0121
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0039 0.0022 0.0078
Trichomonas vaginalis glutathione reductase, putative 0.0046 0.0033 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0023 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0036
Brugia malayi mbt repeat family protein 0.0051 0.0042 0.0148
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0887 0.1399 0.3548
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0107 0.0132 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0075 0.027
Trichomonas vaginalis tubulin, putative 0.0284 0.0421 0.1236
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0072 0.0075 0.0478
Onchocerca volvulus 0.0034 0.0013 0.0082
Loa Loa (eye worm) neuropeptide F receptor 0.0434 0.0663 0.1969
Plasmodium falciparum protoporphyrinogen oxidase 0.0043 0.0029 0.0085
Plasmodium vivax aspartyl proteinase, putative 0.2095 0.3364 1
Loa Loa (eye worm) hypothetical protein 0.1727 0.2764 0.8217
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0713 0.1116 0.4037
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0052 0.0044 0.0109
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0114 0.0143 0.0424
Echinococcus granulosus X box binding protein 1 0.0287 0.0424 0.126
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0104 0.0292
Treponema pallidum NADH oxidase 0.0046 0.0033 0.0591
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.005 0.0177
Echinococcus multilocularis sterol regulatory element binding protein 0.0086 0.0098 0.0247
Plasmodium falciparum plasmepsin VII 0.0495 0.0764 0.227
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.002 0.0019
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0072 0.0075 0.0222
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0163 0.0162
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Brugia malayi hypothetical protein 0.0088 0.0101 0.0362
Echinococcus multilocularis 0.0043 0.0029 0.0071
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.014 0.1142
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0114 0.0143 0.0142
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0434 0.0663 0.168
Mycobacterium tuberculosis Cell division protein FtsZ 0.0252 0.0367 0.3204
Echinococcus multilocularis tar DNA binding protein 0.0452 0.0693 0.1756
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0053 0.0156
Brugia malayi nuclear hormone receptor 0.0072 0.0075 0.027
Echinococcus multilocularis hypothetical protein 0.0739 0.116 0.2941
Leishmania major pyruvate kinase 0.0074 0.0078 0.0397
Echinococcus granulosus neuropeptide s receptor 0.0887 0.1399 0.4158
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.005 0.0148
Brugia malayi beta-lactamase family protein 0.0112 0.014 0.0503
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0163 0.0162
Brugia malayi NNMT/PNMT/TEMT family protein 0.1727 0.2764 1
Echinococcus granulosus geminin 0.1741 0.2788 0.8288
Echinococcus multilocularis lysine specific demethylase 5A 0.019 0.0267 0.0676
Onchocerca volvulus 0.0434 0.0663 0.4242
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0088 0.0101 0.0604
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0069 0.0405
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0049 0.0122
Loa Loa (eye worm) Smad1 0.0058 0.0053 0.0156
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0037 0.0631
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0114 0.0143 0.0515
Plasmodium falciparum alpha tubulin 1 0.0739 0.116 0.3448
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0311 0.0464 0.1364
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0072 0.0075 0.0222
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0029 0.0247
Onchocerca volvulus 0.0434 0.0663 0.4242
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0039 0.0022 0.0055
Echinococcus multilocularis pyruvate kinase 0.0038 0.002 0.0048
Brugia malayi G-protein coupled receptor 0.0434 0.0663 0.2396
Brugia malayi excitatory GABA receptor EXP-1A 0.0114 0.0143 0.0515
Giardia lamblia Delta tubulin 0.0252 0.0367 0.2302
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0089 0.0104 0.0261
Trypanosoma brucei tubulin gamma chain 0.0583 0.0906 0.574
Brugia malayi Fli-1 protein 0.0215 0.0308 0.1114
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0028 0.0084
Echinococcus multilocularis pyruvate kinase 0.0058 0.0053 0.0132
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.0163 0.0939
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0037 0.0631
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Leishmania major beta tubulin 0.0997 0.1578 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0204 0.029 0.2498
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0204 0.029 0.5723
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0434 0.0663 0.4242
Brugia malayi G-protein alpha subunit 0.0039 0.0022 0.0078
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0037 0.033
Schistosoma mansoni tubulin subunit beta 0.0252 0.0367 0.0367
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0029 0.0146
Leishmania major cytochrome p450-like protein 0.0071 0.0074 0.0374
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0037 0.0199
Chlamydia trachomatis protoporphyrinogen oxidase 0.0043 0.0029 0.0503
Onchocerca volvulus 0.0072 0.0075 0.0478
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0114 0.0143 0.0515
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.0083
Echinococcus granulosus Solute carrier organic anion transporter family 0.0067 0.0068 0.0199
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0713 0.1116 0.7065
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0091 0.0269
Echinococcus multilocularis tubulin subunit TubB 0.0739 0.116 0.2941
Schistosoma mansoni amine GPCR 0.0434 0.0663 0.0662
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0218 0.0647
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0091 0.0091
Echinococcus granulosus tubulin alpha chain 0.0739 0.116 0.3447
Echinococcus granulosus pyruvate kinase 0.0038 0.002 0.0057
Toxoplasma gondii histone lysine-specific demethylase 0.0043 0.0029 0.0069
Echinococcus granulosus Niemann Pick C1 protein 0.0201 0.0284 0.0843
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0915 0.1446 0.1445
Brugia malayi MH2 domain containing protein 0.0058 0.0053 0.019
Trypanosoma cruzi cytochrome P450, putative 0.0097 0.0117 0.0707
Loa Loa (eye worm) hypothetical protein 0.0112 0.014 0.0414
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0072 0.0075 0.0075
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0434 0.0663 0.2396
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.014 0.04
Echinococcus granulosus thioredoxin glutathione reductase 0.0133 0.0174 0.0516
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0106
Toxoplasma gondii NADPH-glutathione reductase 0.0046 0.0033 0.0081
Brugia malayi Ets-domain containing protein 0.0071 0.0074 0.0264
Onchocerca volvulus 0.0434 0.0663 0.4242
Loa Loa (eye worm) tubulin gamma chain 0.0583 0.0906 0.2691
Plasmodium vivax glutathione reductase, putative 0.0132 0.0173 0.0513
Entamoeba histolytica tubulin gamma chain 0.0583 0.0906 0.5725
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0039 0.0022 0.0064
Plasmodium vivax tubulin alpha chain, putative 0.0739 0.116 0.3448
Trypanosoma cruzi pyruvate kinase 2, putative 0.0074 0.0078 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0028 0.0068
Trichomonas vaginalis tubulin alpha chain, putative 0.0997 0.1578 0.4682
Leishmania major importin beta-1 subunit, putative 0.0096 0.0115 0.0634
Echinococcus multilocularis serotonin receptor 0.0434 0.0663 0.168
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0426 0.1251
Echinococcus multilocularis thioredoxin glutathione reductase 0.0133 0.0174 0.044
Mycobacterium ulcerans lipase LipD 0.0112 0.014 0.1414
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0114 0.0143 0.0515
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0039 0.0022 0.0022
Mycobacterium ulcerans monoamine oxidase 0.0043 0.0029 0.0242
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0022 0.0055
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0612 0.0953 0.2831
Trichomonas vaginalis tubulin beta chain, putative 0.0739 0.116 0.3438
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.01 0.0297
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0071 0.0074 0.0725
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0039 0.0022 0.0064
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0065 0.0064 0.0308
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0426 0.1251
Leishmania major beta tubulin 0.0997 0.1578 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0072 0.0075 0.027
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0114 0.0143 0.0142
Onchocerca volvulus 0.0696 0.109 0.6977
Echinococcus granulosus tubulin alpha chain 0.0739 0.116 0.3447
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Leishmania major sterol C-24 reductase, putative 0.0098 0.0118 0.0655
Loa Loa (eye worm) hypothetical protein 0.0048 0.0037 0.0108
Schistosoma mansoni nAChR subunit 0.0114 0.0143 0.0142
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0037 0.0209
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.0058
Brugia malayi Tubulin alpha chain 0.0739 0.116 0.4195
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Brugia malayi putative neuropeptide receptor NPR1 0.0434 0.0663 0.2396
Toxoplasma gondii aspartyl protease ASP3 0.0495 0.0764 0.2257
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.0013 0.0038
Schistosoma mansoni neurotransmitter gated ion channel 0.0052 0.0044 0.0043
Onchocerca volvulus 0.0067 0.0068 0.043
Mycobacterium tuberculosis Probable reductase 0.0301 0.0447 0.3926
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0104 0.0103
Echinococcus granulosus tubulin alpha 3 chain 0.0739 0.116 0.3447
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0029 0.0005 0.00000040672
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.0083
Leishmania major DNA polymerase eta, putative 0.0038 0.002 0.0024
Loa Loa (eye worm) tubulin alpha-3 chain 0.0441 0.0675 0.2005
Echinococcus multilocularis Smad4 0.0058 0.0053 0.0133
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0028 0.0027
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Echinococcus multilocularis g protein coupled receptor 0.0434 0.0663 0.168
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0051 0.0041 0.0105
Echinococcus granulosus tubulin gamma 1 chain 0.0583 0.0906 0.2691
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0037 0.033
Loa Loa (eye worm) hypothetical protein 0.0048 0.0037 0.0108
Loa Loa (eye worm) tubulin alpha chain 0.0739 0.116 0.3447
Echinococcus multilocularis tubulin alpha chain 0.0739 0.116 0.2941
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0046 0.0033 0.0097
Schistosoma mansoni hypothetical protein 0.0434 0.0663 0.0662
Brugia malayi tubulin alpha chain - mouse 0.0739 0.116 0.4195
Schistosoma mansoni hypothetical protein 0.0434 0.0663 0.0662
Loa Loa (eye worm) hypothetical protein 0.0058 0.0053 0.0157
Loa Loa (eye worm) hypothetical protein 0.0112 0.014 0.0414
Schistosoma mansoni tar DNA-binding protein 0.0452 0.0693 0.0692
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.005 0.0281
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0071 0.0074 0.0549
Trypanosoma brucei beta tubulin 0.0997 0.1578 1
Echinococcus granulosus pyruvate kinase 0.0038 0.002 0.0057
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0033 0.0082
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0058 0.0369
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0434 0.0663 0.2396
Onchocerca volvulus 0.0114 0.0143 0.0912
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Echinococcus granulosus hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0058 0.0171
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0029 0.0085
Echinococcus multilocularis pyruvate kinase 0.0074 0.0078 0.0196
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0071 0.0074 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0011 0.0016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Echinococcus multilocularis sex peptide receptor 0.0434 0.0663 0.168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0348 0.0523 0.1554
Leishmania major pyruvate kinase 0.0074 0.0078 0.0397
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0069 0.0203
Loa Loa (eye worm) hypothetical protein 0.0089 0.0104 0.0306
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0075 0.027
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0022 0.0065
Schistosoma mansoni neurotransmitter gated ion channel 0.0061 0.0058 0.0057
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.0047 0.0196
Brugia malayi Tubulin beta chain 0.0299 0.0444 0.1602
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0088 0.0101 0.0299
Trypanosoma cruzi PAB1-binding protein , putative 0.0208 0.0297 0.1852
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0915 0.1446 0.523
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0039 0.0022 0.0022
Echinococcus granulosus Tubulin beta 2C chain 0.0997 0.1578 0.469
Loa Loa (eye worm) nuclear factor I 0.0032 0.0011 0.003
Onchocerca volvulus 0.0052 0.0044 0.0274
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.0013 0.0013
Brugia malayi SPARC precursor 0.0046 0.0033 0.0117
Trichomonas vaginalis replication factor C large subunit, putative 0.0029 0.0005 0.00000040672
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0434 0.0663 0.0662
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0034 0.0084
Loa Loa (eye worm) hypothetical protein 0.0253 0.037 0.1097
Schistosoma mansoni tar DNA-binding protein 0.0452 0.0693 0.0692
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.014 0.0139
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.0047 0.0046
Brugia malayi Dopamine receptor protein 1 0.1246 0.1984 0.7174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0434 0.0663 0.2396
Schistosoma mansoni GTP-binding protein alpha subunit 0.0039 0.0022 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0047 0.0137
Schistosoma mansoni steroid hormone receptor ad4bp 0.0072 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Giardia lamblia PHD finger protein 15 0.0062 0.0059 0.0343
Trichomonas vaginalis mercuric reductase, putative 0.0046 0.0033 0.0081
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0044 0.0155
Echinococcus multilocularis lipoxygenase domain containing protein 0.0071 0.0074 0.0187
Echinococcus granulosus glycine receptor subunit beta 0.0114 0.0143 0.0423
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0041 0.0119
Brugia malayi G-protein coupled receptor 0.0434 0.0663 0.2396
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0054 0.0047 0.0261
Echinococcus multilocularis peregrin 0.0069 0.0071 0.0179
Brugia malayi Muscleblind-like protein 0.0144 0.0193 0.0695
Brugia malayi hypothetical protein 0.0038 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0739 0.116 0.3447
Onchocerca volvulus 0.0043 0.0029 0.0181
Echinococcus multilocularis nibrin 0.0029 0.0005 0.0012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0434 0.0663 0.2396
Brugia malayi PHD-finger family protein 0.0062 0.0059 0.0212
Trichomonas vaginalis tubulin gamma chain, putative 0.0583 0.0906 0.2681
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.014 0.04
Brugia malayi MH2 domain containing protein 0.0856 0.135 0.4882
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0071 0.0074 0.0725
Schistosoma mansoni jumonji domain containing protein 0.0277 0.0408 0.0407
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Onchocerca volvulus 0.0043 0.0028 0.0176
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0074 0.0185
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0039 0.0022 0.005
Trypanosoma brucei pyruvate kinase 1, putative 0.0074 0.0078 0.0494
Brugia malayi hypothetical protein 0.0071 0.0074 0.0267
Loa Loa (eye worm) pyruvate kinase-PB 0.0051 0.0042 0.0123
Loa Loa (eye worm) glutathione reductase 0.0132 0.0173 0.0512
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0073 0.0183
Brugia malayi hypothetical protein 0.0043 0.0028 0.0099
Schistosoma mansoni hypothetical protein 0.0071 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0064
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0114 0.0143 0.0361
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0214 0.0305 0.0906
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0218 0.0787
Loa Loa (eye worm) hypothetical protein 0.0713 0.1116 0.3318
Loa Loa (eye worm) tubulin alpha 2 0.0488 0.0751 0.2231
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0426 0.1251
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0071 0.0074 0.0725
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0297 0.0441 0.044
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Leishmania major UDP-galactopyranose mutase 0.0043 0.0029 0.008
Brugia malayi RNA, U transporter 1 0.0338 0.0508 0.1835
Loa Loa (eye worm) carboxylesterase 0.0131 0.0172 0.0509
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0252 0.0367 0.1078
Schistosoma mansoni hypothetical protein 0.0071 0.0074 0.0074
Echinococcus granulosus Polycystic kidney disease protein 0.0071 0.0074 0.0219
Echinococcus granulosus lysine specific demethylase 5A 0.0195 0.0275 0.0816
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1269 0.2022 0.6009
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.014 0.1142
Loa Loa (eye worm) hypothetical protein 0.0495 0.0764 0.2268
Onchocerca volvulus 0.0114 0.0143 0.0912
Echinococcus multilocularis neuropeptide receptor 0.0434 0.0663 0.168
Brugia malayi aspartic protease BmAsp-1, identical 0.0495 0.0764 0.276
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0915 0.1446 0.4298
Echinococcus multilocularis muscleblind protein 0.0144 0.0193 0.0487
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0069 0.0438
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0114 0.0143 0.0515
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0434 0.0663 0.1969
Mycobacterium leprae cell division protein FtsZ 0.0252 0.0367 0.7294
Schistosoma mansoni hypothetical protein 0.0071 0.0074 0.0074
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.005 0.0964
Schistosoma mansoni nuclear hormone receptor 0.0072 0.0075 0.0075
Onchocerca volvulus Protein ultraspiracle homolog 0.0072 0.0075 0.0478
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0042 0.0041
Trichomonas vaginalis tubulin beta chain, putative 0.0997 0.1578 0.4682
Echinococcus multilocularis pyruvate kinase 0.0074 0.0078 0.0196
Trichomonas vaginalis tubulin beta chain, putative 0.0739 0.116 0.3438
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0072 0.0075 0.0222
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0055 0.0055
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0053 0.0133
Echinococcus granulosus single minded 2 0.0047 0.0034 0.01
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1727 0.2764 0.8217
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0172
Echinococcus multilocularis smad 0.0058 0.0053 0.0133
Loa Loa (eye worm) hypothetical protein 0.0061 0.0057 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Brugia malayi MH1 domain containing protein 0.0032 0.0011 0.0036
Onchocerca volvulus 0.0067 0.0068 0.043
Loa Loa (eye worm) aspartyl protease 6 0.0495 0.0764 0.2268
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Schistosoma mansoni hypothetical protein 0.0348 0.0523 0.0523
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Brugia malayi Tubulin gamma chain 0.0583 0.0906 0.3275
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0093 0.011 0.0277
Echinococcus multilocularis Niemann Pick C1 protein 0.0201 0.0284 0.0719
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Echinococcus granulosus glycine receptor subunit alpha 1 0.0114 0.0143 0.0423
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0049 0.0455
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0033 0.0117
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.0058
Plasmodium vivax plasmepsin V, putative 0.0495 0.0764 0.227
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0049
Echinococcus granulosus carboxylesterase 5A 0.0131 0.0172 0.0509
Schistosoma mansoni neurotransmitter gated ion channel 0.0052 0.0044 0.0043
Giardia lamblia Alpha-tubulin 0.0739 0.116 0.7342
Echinococcus multilocularis expressed conserved protein 0.0188 0.0264 0.0669
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0114 0.0143 0.0142
Leishmania major beta tubulin 0.0997 0.1578 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0058 0.0336
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.01 0.0282
Echinococcus granulosus acetylcholinesterase 0.0131 0.0172 0.0509
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0104 0.0103
Brugia malayi hypothetical protein 0.0067 0.0068 0.0243
Loa Loa (eye worm) doublecortin family protein 0.0071 0.0074 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0098 0.0276
Schistosoma mansoni myosin xvIII 0.0434 0.0663 0.0662
Echinococcus multilocularis Tubulin beta 2C chain 0.0997 0.1578 0.4001
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0453 0.0695 0.2053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.014 0.0139
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0013 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0099
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0114 0.0143 0.0423
Echinococcus granulosus lipoxygenase domain containing protein 0.0071 0.0074 0.0219
Echinococcus granulosus tachykinin peptides receptor 99D 0.0434 0.0663 0.1969
Plasmodium falciparum thioredoxin reductase 0.0132 0.0173 0.0513
Schistosoma mansoni pyruvate kinase 0.0074 0.0078 0.0077
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0072 0.0075 0.0222
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.002 0.0069
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0059 0.016
Schistosoma mansoni peptidase Clp (S14 family) 0.0311 0.0464 0.0463
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0039 0.0022 0.005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Schistosoma mansoni hypothetical protein 0.0287 0.0424 0.0424
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0311 0.0464 1
Plasmodium vivax tubulin epsilon chain, putative 0.0582 0.0905 0.269
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.002 0.0024
Echinococcus granulosus nAChR subunit 0.0114 0.0143 0.0423
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0065 0.0064 0.0189
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0058 0.0271
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0114 0.0143 0.0361
Entamoeba histolytica hypothetical protein 0.0071 0.0073 0.0429
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.005 0.0315
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.01 0.0282
Loa Loa (eye worm) hypothetical protein 0.0488 0.0751 0.2231
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0276 0.0406 0.1029
Schistosoma mansoni tubulin subunit beta 0.0997 0.1578 0.1577
Onchocerca volvulus 0.0089 0.0104 0.0659
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Schistosoma mansoni alpha tubulin 0.0739 0.116 0.1159
Giardia lamblia DINP protein human, muc B family 0.0038 0.002 0.009
Onchocerca volvulus 0.0029 0.0005 0.0031
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0152 0.096
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.005 0.0325
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0033 0.0117
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0137 0.0181 0.0538
Echinococcus granulosus g protein coupled receptor 0.0434 0.0663 0.1969
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.005 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Loa Loa (eye worm) acetylcholine receptor protein 0.0052 0.0044 0.0128
Echinococcus multilocularis g protein coupled receptor 0.0434 0.0663 0.168
Echinococcus granulosus neuropeptide receptor 0.0434 0.0663 0.1969
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Leishmania major beta tubulin 0.0997 0.1578 1
Echinococcus granulosus Tubulin beta 2C chain 0.0997 0.1578 0.469
Trypanosoma cruzi tubulin gamma chain 0.0583 0.0906 0.5725
Plasmodium vivax replication factor C subunit 1, putative 0.0029 0.0005 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.0013 0.0046
Brugia malayi jmjC domain containing protein 0.0051 0.0041 0.0145
Echinococcus granulosus tubulin beta 1 chain 0.0997 0.1578 0.469
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0037 0.0133
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.01 0.0298
Mycobacterium ulcerans pyruvate kinase 0.0074 0.0078 0.0763
Schistosoma mansoni opsin-like receptor 0.0434 0.0663 0.0662
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.014 0.0353
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.0013 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0152 0.096
Echinococcus granulosus Smad4 0.0058 0.0053 0.0156
Echinococcus multilocularis thyroid hormone receptor alpha 0.0072 0.0075 0.0189
Schistosoma mansoni cpg binding protein 0.0087 0.01 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Echinococcus multilocularis somatostatin receptor 0.0434 0.0663 0.168
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Schistosoma mansoni amine GPCR 0.0434 0.0663 0.0662
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0311 0.0464 0.1376
Loa Loa (eye worm) hypothetical protein 0.0208 0.0297 0.088
Echinococcus granulosus neuropeptide receptor A26 0.0887 0.1399 0.4158
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0082
Trypanosoma cruzi tubulin delta chain 0.0453 0.0695 0.4385
Echinococcus multilocularis isocitrate dehydrogenase 0.0065 0.0064 0.0161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Trichomonas vaginalis tubulin alpha chain, putative 0.0299 0.0444 0.1304
Echinococcus multilocularis tubulin epsilon chain 0.0582 0.0905 0.2294
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0201 0.0284 0.1773
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Toxoplasma gondii alpha-tubulin I, putative 0.0739 0.116 0.3438
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0028 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0071 0.0074 0.0549
Toxoplasma gondii hypothetical protein 0.0043 0.0028 0.0067
Brugia malayi G protein-coupled receptor 0.0434 0.0663 0.2396
Echinococcus multilocularis RUN 0.0071 0.0074 0.0187
Echinococcus granulosus g-protein coupled receptor 0.0434 0.0663 0.1969
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0043 0.0029 0.0085
Echinococcus multilocularis lipoxygenase domain containing protein 0.0071 0.0074 0.0187
Brugia malayi neuropeptide F receptor 0.0434 0.0663 0.2396
Leishmania major beta tubulin 0.0997 0.1578 1
Schistosoma mansoni tubulin subunit beta 0.0997 0.1578 0.1577
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.0013 0.0046
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0039 0.0022 0.0078
Echinococcus multilocularis neuropeptide FF receptor 2 0.0434 0.0663 0.168
Leishmania major beta tubulin 0.0997 0.1578 1
Schistosoma mansoni alpha-glucosidase 0.0138 0.0182 0.0181
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.002 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0071 0.0074 0.0549
Schistosoma mansoni follistatin 0.0046 0.0033 0.0032
Brugia malayi mbt repeat family protein 0.0051 0.0042 0.0148
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0046 0.0033 0.0206
Echinococcus multilocularis nAChR subunit 0.0061 0.0058 0.0145
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0072 0.0075 0.0222
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0017 0.005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trypanosoma cruzi C-14 sterol reductase, putative 0.0098 0.0118 0.0717
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0052 0.0044 0.0155
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0017 0.005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0915 0.1446 0.4297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0028 0.0068
Giardia lamblia Pyruvate kinase 0.0074 0.0078 0.0461
Loa Loa (eye worm) hypothetical protein 0.0067 0.0068 0.02
Schistosoma mansoni organic anion transporter 0.0067 0.0068 0.0067
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0016 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0163 0.1655
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.005 0.0132
Schistosoma mansoni jumonji/arid domain-containing protein 0.0195 0.0275 0.0275
Echinococcus granulosus tm gpcr rhodopsin 0.0434 0.0663 0.1969
Brugia malayi Cation transporter family protein 0.0114 0.0143 0.0515
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.0013 0.0044
Echinococcus multilocularis tubulin delta chain 0.0252 0.0367 0.0931
Loa Loa (eye worm) hypothetical protein 0.0348 0.0523 0.1555
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0071 0.0074 0.0549
Echinococcus granulosus g protein coupled receptor 0.0434 0.0663 0.1969
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.002 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0071 0.0074 0.0549
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Toxoplasma gondii aspartyl protease 0.0495 0.0764 0.2257
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0078 0.023
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0061 0.0058 0.0207
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0495 0.0764 0.0763
Toxoplasma gondii transporter, major facilitator family protein 0.0067 0.0068 0.0185
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0052 0.0044 0.0155
Echinococcus granulosus GTP binding nuclear protein Ran 0.0088 0.0101 0.0297
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0016 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0044 0.0155
Loa Loa (eye worm) hypothetical protein 0.0122 0.0157 0.0464
Loa Loa (eye worm) hypothetical protein 0.0441 0.0675 0.2005
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0114 0.0143 0.0361
Echinococcus granulosus Tubulin alpha 1 chain 0.0739 0.116 0.3447
Schistosoma mansoni amine GPCR 0.0434 0.0663 0.0662
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Mycobacterium ulcerans oxidoreductase 0.0043 0.0029 0.0242
Echinococcus granulosus tubulin alpha chain 0.0739 0.116 0.3447
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Entamoeba histolytica G protein alpha subunit, putative 0.0039 0.0022 0.0106
Brugia malayi Serotonin receptor 0.0434 0.0663 0.2396
Brugia malayi hypothetical protein 0.0208 0.0297 0.1071
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Schistosoma mansoni alpha-glucosidase 0.0138 0.0182 0.0181
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0053 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0172
Echinococcus multilocularis tubulin alpha 3 chain 0.0739 0.116 0.2941
Schistosoma mansoni tubulin subunit alpha 0.0252 0.0367 0.0367
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0065 0.0064 0.0161
Loa Loa (eye worm) hypothetical protein 0.0253 0.037 0.1097
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0013 0.0032
Brugia malayi jmjC domain containing protein 0.0051 0.0041 0.0145
Loa Loa (eye worm) hypothetical protein 0.0046 0.0033 0.0097
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.01 0.0282
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0071 0.0074 0.0549
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.009
Leishmania major delta tubulin, putative 0.0453 0.0695 0.4347
Echinococcus multilocularis protoporphyrinogen oxidase 0.0043 0.0029 0.0071
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0114 0.0143 0.0424
Echinococcus granulosus neuropeptide Y receptor 0.0434 0.0663 0.1969
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0058 0.0157
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Schistosoma mansoni DNA polymerase eta 0.0038 0.002 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0037 0.0133
Plasmodium falciparum plasmepsin II 0.2095 0.3364 1
Echinococcus granulosus tm gpcr rhodopsin 0.0434 0.0663 0.1969
Onchocerca volvulus 0.006 0.0055 0.035
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0252 0.0367 0.7902
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Leishmania major trypanothione reductase 0.0132 0.0173 0.1003
Plasmodium falciparum phd finger protein, putative 0.0062 0.0059 0.0177
Onchocerca volvulus Pyruvate kinase homolog 0.0074 0.0078 0.0495
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.002 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0033 0.0206
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0488 0.0751 0.2231
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0046 0.0033 0.0081
Mycobacterium ulcerans hypothetical protein 0.0048 0.0037 0.033
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0039 0.0022 0.005
Loa Loa (eye worm) tubulin beta chain 0.0252 0.0367 0.1091
Leishmania major hypothetical protein, conserved 0.0208 0.0297 0.1797
Loa Loa (eye worm) melatonin receptor type 1A 0.0434 0.0663 0.1969
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0072 0.0075 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0426 0.1251
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0037 0.033
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0028 0.0082
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0132 0.0173 0.1439
Brugia malayi Dopamine receptor 0.0434 0.0663 0.2396
Echinococcus granulosus expressed protein 0.0039 0.0022 0.0064
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.014 0.1414
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0071 0.0074 0.0725
Echinococcus multilocularis tumor protein p63 0.0408 0.0621 0.1575
Mycobacterium leprae Probable lipase LipE 0.0112 0.014 0.2707
Echinococcus granulosus snurportin 1 0.1269 0.2022 0.6008
Echinococcus multilocularis neuropeptides capa receptor 0.0434 0.0663 0.168
Echinococcus granulosus JmjC domain containing protein 4 0.0051 0.0041 0.0119
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0434 0.0663 0.168
Plasmodium vivax importin-beta 2, putative 0.0119 0.0152 0.0451
Echinococcus granulosus neuropeptide receptor 0.0434 0.0663 0.1969
Trypanosoma cruzi trypanothione reductase, putative 0.0132 0.0173 0.1063
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0071 0.0074 0.0549
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.0029 0.0146
Brugia malayi CXXC zinc finger family protein 0.0087 0.01 0.036
Loa Loa (eye worm) hypothetical protein 0.0131 0.0172 0.0509
Loa Loa (eye worm) cytochrome P450 family protein 0.0097 0.0117 0.0345
Brugia malayi topoisomerase 0.0029 0.0005 0.0017
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.002 0.0019
Loa Loa (eye worm) alpha-tubulin 0.0739 0.116 0.3447
Trichomonas vaginalis set domain proteins, putative 0.0696 0.109 0.3229
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Onchocerca volvulus 0.0434 0.0663 0.4242
Schistosoma mansoni Smad4 0.0058 0.0053 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Loa Loa (eye worm) MH2 domain-containing protein 0.0058 0.0053 0.0156
Schistosoma mansoni tubulin subunit beta 0.0997 0.1578 0.1577
Leishmania major beta tubulin 0.0997 0.1578 1
Leishmania major beta tubulin 0.0997 0.1578 1
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Loa Loa (eye worm) pax transcription factor protein 2 0.0987 0.1562 0.4642
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0053 0.0133
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0334 0.0502 0.442
Trichomonas vaginalis tubulin gamma chain, putative 0.0252 0.0367 0.1078
Plasmodium vivax delta tubulin, putative 0.0252 0.0367 0.1092
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Onchocerca volvulus 0.0114 0.0143 0.0912
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0039 0.0022 0.0022
Echinococcus multilocularis follistatin 0.0046 0.0033 0.0082
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.002 0.0125
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.0047 0.0116
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Schistosoma mansoni neuropeptide F-like receptor 0.0434 0.0663 0.0662
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.002 0.009
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0043 0.0029 0.0085
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0013 0.0032
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.014 0.04
Brugia malayi hypothetical protein 0.0071 0.0074 0.0267
Echinococcus multilocularis Tubulin alpha 1 chain 0.0739 0.116 0.2941
Brugia malayi TAR-binding protein 0.0452 0.0693 0.2505
Onchocerca volvulus 0.0434 0.0663 0.4242
Loa Loa (eye worm) beta-lactamase 0.0112 0.014 0.0414
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0114 0.0143 0.0423
Echinococcus multilocularis rhodopsin orphan GPCR 0.0434 0.0663 0.168
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0016 0.0031
Trypanosoma cruzi alpha tubulin, putative 0.0739 0.116 0.7342
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0218 0.0646
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.014 0.0854
Loa Loa (eye worm) hypothetical protein 0.0086 0.0098 0.029
Echinococcus granulosus dna polymerase eta 0.0038 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0052 0.0044 0.0128
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0075 0.0189
Onchocerca volvulus Alhambra homolog 0.0062 0.0059 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0024 0.0055
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0119
Echinococcus multilocularis neuropeptide Y receptor 0.0434 0.0663 0.168
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0074 0.0217
Loa Loa (eye worm) acetyltransferase 0.0297 0.0441 0.1309
Loa Loa (eye worm) hypothetical protein 0.0048 0.0037 0.0108
Echinococcus granulosus histone acetyltransferase KAT2B 0.0289 0.0427 0.1269
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0071 0.0074 0.0549
Brugia malayi Niemann-Pick C1 protein precursor 0.0201 0.0284 0.1026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0172
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0039 0.0022 0.0022
Loa Loa (eye worm) tubulin beta-2A chain 0.0997 0.1578 0.469
Schistosoma mansoni smad1 5 8 and 0.0058 0.0053 0.0052
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0061 0.0058 0.0207
Schistosoma mansoni biogenic amine receptor 0.0434 0.0663 0.0662
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0052 0.0044 0.0128
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0039 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.0058
Brugia malayi hypothetical protein 0.0434 0.0663 0.2396
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0068 0.0243
Echinococcus granulosus 7tm_1 domain containing protein 0.0434 0.0663 0.1969
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0072 0.0075 0.0189
Trypanosoma brucei C-8 sterol isomerase, putative 0.0713 0.1116 0.7075
Schistosoma mansoni agrin 0.0046 0.0033 0.0032
Trichomonas vaginalis tubulin epsilon chain, putative 0.0252 0.0367 0.1078
Entamoeba histolytica tubulin alpha-1 chain 0.0739 0.116 0.7342
Toxoplasma gondii alpha tubulin TUBA1 0.0739 0.116 0.3438
Toxoplasma gondii cytochrome p450 superfamily protein 0.0071 0.0074 0.0205
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0071 0.0074 0.0549
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0043 0.0029 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0072 0.0075 0.027
Echinococcus granulosus jumonji domain containing 1A 0.0051 0.0041 0.0119
Brugia malayi Smad1 0.0058 0.0053 0.019
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Schistosoma mansoni cpg binding protein 0.0092 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0112 0.014 0.0414
Echinococcus granulosus tubulin delta chain 0.0252 0.0367 0.1091
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0039 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0071 0.0074 0.0725
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.0058
Toxoplasma gondii hypothetical protein 0.0043 0.0028 0.0067
Brugia malayi hypothetical protein 0.0197 0.0279 0.1006
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0016 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0452 0.0693 0.0692
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0915 0.1446 0.3667
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.0013 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0047 0.0122
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0097 0.0117 0.117
Onchocerca volvulus 0.0112 0.014 0.0891
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0065 0.0064 0.0373
Echinococcus multilocularis neuropeptides capa receptor 0.0434 0.0663 0.168
Loa Loa (eye worm) hypothetical protein 0.0144 0.0193 0.0572
Loa Loa (eye worm) cytochrome P450 family protein 0.0097 0.0117 0.0345
Loa Loa (eye worm) hypothetical protein 0.0105 0.013 0.0384
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0028 0.0082
Entamoeba histolytica tubulin alpha chain, putative 0.0739 0.116 0.7342
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0065 0.0064 0.0161
Onchocerca volvulus 0.0495 0.0764 0.4886
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.002 0.0125
Echinococcus granulosus cpg binding protein 0.0092 0.0108 0.032
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.005 0.0964
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.2095 0.3364 1
Onchocerca volvulus Pyruvate kinase homolog 0.0074 0.0078 0.0495
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0029 0.0102
Loa Loa (eye worm) MH2 domain-containing protein 0.0856 0.135 0.4012
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0613 0.0955 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.002 0.0054
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.002 0.015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0072 0.0075 0.027
Brugia malayi RNA recognition motif domain containing protein 0.0452 0.0693 0.2505
Echinococcus multilocularis 0.0071 0.0074 0.0187
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0071 0.0074 0.0471
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0043 0.0029 0.0028
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0434 0.0663 0.0662
Echinococcus granulosus tubulin alpha chain 0.0739 0.116 0.3447
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.0431 0.9292
Schistosoma mansoni ap endonuclease 0.0056 0.005 0.0049
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Onchocerca volvulus 0.0048 0.0037 0.0231
Brugia malayi Pre-SET motif family protein 0.0089 0.0104 0.0372
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0028 0.0027
Loa Loa (eye worm) BEN-1 protein 0.0997 0.1578 0.469
Loa Loa (eye worm) agrin synaptic family protein 0.0046 0.0033 0.0097
Schistosoma mansoni survival motor neuron protein 0.0145 0.0194 0.0193
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0434 0.0663 0.0662
Echinococcus multilocularis expressed protein 0.0046 0.0033 0.0082
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0218 0.0552
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.2095 0.3364 0.8532
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.0047 0.0196
Echinococcus multilocularis tubulin alpha 1C chain 0.0739 0.116 0.2941
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.0163 0.0482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0028 0.0068
Schistosoma mansoni RAR-like nuclear receptor 0.0072 0.0075 0.0075
Trichomonas vaginalis tubulin beta chain, putative 0.0739 0.116 0.3438
Brugia malayi Probable ClpP-like protease 0.0311 0.0464 0.1675
Loa Loa (eye worm) G-protein coupled receptor 0.0434 0.0663 0.1969
Schistosoma mansoni tubulin subunit alpha 0.0739 0.116 0.1159
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0253 0.037 0.1335
Trichomonas vaginalis conserved hypothetical protein 0.0252 0.0367 0.1078
Toxoplasma gondii aspartyl protease ASP1 0.2095 0.3364 1
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.002 0.007
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0043 0.0029 0.0464
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0069 0.0174
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0013 0.0032
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0037 0.0199
Schistosoma mansoni hypothetical protein 0.0145 0.0194 0.0193
Schistosoma mansoni tubulin subunit epsilon 0.0582 0.0905 0.0904
Trypanosoma brucei trypanothione reductase 0.0132 0.0173 0.1094
Echinococcus multilocularis replication factor c subunit 1 0.0029 0.0005 0.0012
Schistosoma mansoni rab6-interacting 0.0071 0.0074 0.0074
Plasmodium vivax tubulin gamma chain, putative 0.0583 0.0906 0.2693
Echinococcus multilocularis beta tubulin 0.0997 0.1578 0.4001
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0058 0.0157
Echinococcus granulosus glycine receptor subunit beta 0.0114 0.0143 0.0423
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0284 0.042 0.1233
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0434 0.0663 0.168
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0088 0.0101 0.0604
Toxoplasma gondii LsmAD domain-containing protein 0.0208 0.0297 0.0867
Entamoeba histolytica hypothetical protein 0.0071 0.0073 0.0429
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0069 0.0405
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0114 0.0143 0.0424
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0434 0.0663 0.0662
Brugia malayi hypothetical protein 0.0067 0.0068 0.0243
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.0057
Loa Loa (eye worm) tubulin alpha 2 0.0488 0.0751 0.2231
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.0047 0.0136
Loa Loa (eye worm) hypothetical protein 0.0495 0.0764 0.2268
Trichomonas vaginalis tubulin alpha chain, putative 0.0299 0.0444 0.1304
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.014 0.0886
Onchocerca volvulus 0.0046 0.0033 0.0207
Echinococcus multilocularis protein dispatched 1 0.0098 0.0118 0.0297
Loa Loa (eye worm) hypothetical protein 0.071 0.1112 0.3306
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0431 0.1267
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0434 0.0663 0.168
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Echinococcus multilocularis tubulin beta 1 chain 0.0997 0.1578 0.4001
Echinococcus granulosus rhodopsin orphan GPCR 0.0434 0.0663 0.1969
Echinococcus multilocularis FTZ F1 alpha 0.0072 0.0075 0.0189
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0434 0.0663 0.0662
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0114 0.0143 0.0515
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0114 0.0143 0.0423
Echinococcus granulosus muscleblind protein 0.0144 0.0193 0.0571
Plasmodium falciparum plasmepsin III 0.0495 0.0764 0.227
Brugia malayi steroid hormone receptor 0.0072 0.0075 0.027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0033 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0112 0.014 0.0416
Echinococcus multilocularis G-protein coupled receptor, putative 0.0434 0.0663 0.168
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0069 0.0405
Onchocerca volvulus Putative nachr subunit 0.0114 0.0143 0.0912
Loa Loa (eye worm) norepinephrine transporter 0.0253 0.037 0.1097
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.002 0.0058
Echinococcus multilocularis dna polymerase kappa 0.0038 0.002 0.0048
Onchocerca volvulus 0.0434 0.0663 0.4242
Echinococcus multilocularis snurportin 1 0.1269 0.2022 0.5126
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0015
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.0013 0.0039
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0028 0.0084
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0051 0.0041 0.0224
Giardia lamblia Pyruvate kinase 0.0038 0.002 0.009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0084 0.0095 0.0281
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0068 0.043
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.017
Echinococcus granulosus peroxisome assembly protein 26 0.0739 0.116 0.3447
Mycobacterium ulcerans cell division protein FtsZ 0.0252 0.0367 0.3811
Echinococcus granulosus importin subunit beta 1 0.0119 0.0152 0.0449
Trichomonas vaginalis tubulin beta chain, putative 0.0739 0.116 0.3438
Brugia malayi hypothetical protein 0.0134 0.0177 0.0637
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0434 0.0663 0.168
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0028 0.0082
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0071 0.0074 0.0725
Onchocerca volvulus 0.0495 0.0764 0.4886
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0434 0.0663 0.0662
Onchocerca volvulus 0.0434 0.0663 0.4242
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0434 0.0663 0.0662
Loa Loa (eye worm) hypothetical protein 0.0958 0.1515 0.4503
Plasmodium falciparum plasmepsin IV 0.2095 0.3364 1
Brugia malayi CHE-14 protein 0.0086 0.0098 0.0353
Onchocerca volvulus 0.0434 0.0663 0.4242
Schistosoma mansoni protein phosphatase 2C 0.0051 0.0041 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0075 0.0189
Leishmania major alpha tubulin 0.0739 0.116 0.7324
Echinococcus multilocularis acetylcholinesterase 0.0131 0.0172 0.0434
Schistosoma mansoni tubulin subunit delta 0.0252 0.0367 0.0367
Schistosoma mansoni retinoic acid receptor RXR 0.0072 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0197 0.0279 0.0827
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.01 0.0282
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0071 0.0074 0.0725
Schistosoma mansoni neuropeptide receptor 0.0434 0.0663 0.0662
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0071 0.0074 0.0549
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0114 0.0143 0.0361
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0039 0.0022 0.0064
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0071 0.0074 0.0438
Trypanosoma cruzi beta tubulin, putative 0.0997 0.1578 1
Brugia malayi GnHR receptor homolog 0.0434 0.0663 0.2396
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0072 0.0075 0.0222
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0072 0.0075 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0075 0.027
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0091 0.023
Echinococcus granulosus somatostatin receptor 0.0434 0.0663 0.1969
Echinococcus multilocularis allatostatin A receptor 0.0434 0.0663 0.168
Brugia malayi hypothetical protein 0.0305 0.0454 0.1641
Schistosoma mansoni tubulin subunit beta 0.0997 0.1578 0.1577
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.002 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.005 0.0146
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0739 0.116 0.3438
Onchocerca volvulus Huntingtin homolog 0.0122 0.0157 0.0998
Schistosoma mansoni amine GPCR 0.0434 0.0663 0.0662
Echinococcus granulosus 7TM GPCR rhodopsin 0.0434 0.0663 0.1969
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0072 0.0075 0.0189
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.005 0.0124
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.014 0.0503
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2452 0.3943 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0114 0.0143 0.0515
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0073 0.0072
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0033 0.0206
Echinococcus multilocularis mothers against decapentaplegic 5 0.0058 0.0053 0.0133
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0039 0.0022 0.0022
Brugia malayi Cytochrome P450 family protein 0.0097 0.0117 0.0419
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0043 0.0029 0.0028
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.0163 0.1349
Chlamydia trachomatis pyruvate kinase 0.0074 0.0078 0.1582
Brugia malayi larval opioid receptor 0.0434 0.0663 0.2396
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0033 0.0591
Loa Loa (eye worm) TAR-binding protein 0.0452 0.0693 0.2059
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0301 0.0447 0.8901
Loa Loa (eye worm) hypothetical protein 0.0072 0.0075 0.0222
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0265 0.0772
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0058 0.0336
Trypanosoma cruzi MFS transporter, putative 0.0067 0.0068 0.0396
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0311 0.0464 0.1378
Schistosoma mansoni organic anion transporter 0.0067 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.0083
Schistosoma mansoni smad 0.0058 0.0053 0.0052
Echinococcus granulosus tubulin alpha 1C chain 0.0739 0.116 0.3447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0006 0.0001
Echinococcus granulosus peregrin 0.0069 0.0071 0.021
Plasmodium vivax SET domain protein, putative 0.0089 0.0104 0.0308
Loa Loa (eye worm) hypothetical protein 0.0034 0.0013 0.0039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0082
Loa Loa (eye worm) hypothetical protein 0.0114 0.0143 0.0424
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0096 0.0115 0.0326
Echinococcus granulosus dna polymerase kappa 0.0038 0.002 0.0057
Echinococcus granulosus tubulin subunit beta 0.0997 0.1578 0.469
Loa Loa (eye worm) hypothetical protein 0.0434 0.0663 0.1969
Echinococcus multilocularis tubulin alpha chain 0.0739 0.116 0.2941
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0348 0.0523 0.1554
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0071 0.0074 0.0725
Trypanosoma brucei PAB1-binding protein , putative 0.0208 0.0297 0.188
Schistosoma mansoni topbp1 0.0029 0.0005 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0013 0.0013
Onchocerca volvulus 0.0052 0.0044 0.0274
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0029 0.0134
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.0047 0.0295

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) = 1 Statistical significance of IC 50 values; Expressed as R value ChEMBL. 9207950
Activity (functional) = 31.3 pM of drug (10e6*cells)-1 Compound was tested for amount of net intracellular accumulation per 1 E6 DOX-resistant (DOX/R) cells, after exposure to 1.0 microM for 2 hrs ChEMBL. No reference
Activity (functional) = 69.7 pM of drug (10e6*cells)-1 Compound was tested for amount of net intracellular accumulation per 1 E6 DOX-resistant (DOX/R) cells, after exposure to 2.0 microM for 2 hrs ChEMBL. No reference
Activity (functional) = 84.8 pM of drug (10e6*cells)-1 Compound was evaluated for amount of net intracellular accumulation per 1 E6 hydroxyrubicin-resistant (WP159/R) cells, after exposure to 1.0 microM for 2 hrs ChEMBL. No reference
Activity (functional) = 90.9 pM of drug (10e6*cells)-1 Compound was tested for amount of net intracellular accumulation per 1 E6 J774.2 cells after their exposure to 1.0 microM for 2 hrs ChEMBL. No reference
Activity (functional) = 140.3 pM of drug (10e6*cells)-1 Compound was evaluated for amount of net intracellular accumulation per 1 x 10 e6 hydroxyrubicin-resistant (WP159/R) cells, after exposure to the compound at 2.0 microM for 2 hrs ChEMBL. No reference
Activity (functional) = 163.3 pM of drug (10e6*cells)-1 Compound was tested for amount of net intracellular accumulation per 1 E6 J774.2 cells after their exposure to 2.0 microM for 2 hrs ChEMBL. No reference
Bullatacin index (ADMET) = 18.8 Bullaticin index relates the IC50 values by normalizing to the value of bullatacin for easy comparison. ChEMBL. 9207950
EC50 (functional) = 0.0012 uM Cytotoxic activity of the compound against human epidermoid carcinoma cells (KB) ChEMBL. 10780917
EC50 (functional) < 3.7 uM Cytotoxic activity against african green monkey (C. aethiops) kidney epithelial cells (VERO) ChEMBL. 10780917
ED (functional) = 0.0015 ug ml-1 In vitro antimitotic activity against HeLa cells after 6 hours exposure ChEMBL. 2362275
f1 (binding) = 0.4 Fraction of high affinity at binding site of human P-Glycoprotein (P-gp) in two-affinity model ChEMBL. 12477351
GI50 (functional) = 1 ng ml-1 In vitro cytotoxic activity (growth inhibition) of compound against HCT 116 cancer cell line was determined ChEMBL. 12372531
GI50 (functional) = 10.2 ng ml-1 In vitro cytotoxic activity (growth inhibition) of compound against PC-12 human cancer cell line was determined ChEMBL. 12372531
GI50 (functional) = 0.000003 uM Tested for the inhibitory concentration against cell growth of human leukemic cell line RPMI8226 ChEMBL. 11858989
GI50 (functional) = 0.00002 uM Tested for the inhibitory concentration against cell growth of human leukemic cell line CCRF-CEM ChEMBL. 11858989
GI50 (functional) = 0.000036 uM Tested for the inhibitory concentration against cell growth of human leukemic cell line HL60 ChEMBL. 11858989
GI50 (functional) < 0.00025 uM Tested for the inhibitory concentration against cell growth of human leukemic cell line MOLT-4 ChEMBL. 11858989
GI50 (functional) < 0.00025 uM Tested for the inhibitory concentration against cell growth of human leukemic cell line HuT78 ChEMBL. 11858989
GI50 (functional) < 0.00025 uM Tested for the inhibitory concentration against cell growth of human leukemic cell line K562 ChEMBL. 11858989
IC50 (functional) = 0.0000000017 M The compound was evaluated in vitro for the inhibition of murine leukemia P388D1 cell proliferation. ChEMBL. No reference
IC50 (functional) = 0.0000000082 M The compound was evaluated in vitro for the inhibition of P388D1 cell colony formation. ChEMBL. No reference
IC50 (functional) = 3.9 mg ml-1 Cytotoxicity against MCF-7/Adr cells. ChEMBL. 9207950
IC50 (functional) = 0.49 nM Cytotoxicity against human MDA-MB-435 cells after 72 hrs by cell proliferation assay ChEMBL. 26523419
IC50 (functional) = 0.8 nM Inhibitory concentration required for cytotoxicity in hydroxyrubicin-resistant (WP159/R) cells ChEMBL. No reference
IC50 (functional) = 2.1 nM Inhibitory concentration required for cytotoxicity in J774.2 murine macrophage-like cells ChEMBL. No reference
IC50 (functional) = 3.2 nM Cytotoxicity against human LNCAP cells after 72 hrs by AlamarBlue end point assay ChEMBL. 26600001
IC50 (functional) = 3.4 nM Antiproliferative activity against the human non small cell lung carcinoma cell line NCI-H460 ChEMBL. 11814821
IC50 (functional) = 15.9 nM Inhibitory concentration required for cytotoxicity in DOX-resistant (DOX/R) cells ChEMBL. No reference
IC50 (functional) = 18 nM Inhibitory concentration against the growth of HET-SR-2SC-LNM cell line after 72 h of drug exposure by MTT test ChEMBL. 12431060
IC50 (functional) = 43 nM Antiproliferative activity against the MDR positive human colon adenocarcinoma cell line HCT-15 ChEMBL. 11814821
IC50 (functional) = 246 nM Inhibitory concentration against the growth of 2SC/20 cell line after 72 h of drug exposure by MTT test ChEMBL. 12431060
IC50 (functional) = 0.02 ug ml-1 Cytotoxicity against human MCF7 cells by MTT assay ChEMBL. 16480866
IC50 (functional) = 0.025 ug ml-1 Cytotoxicity against human PA1 cells by MTT assay ChEMBL. 16480866
IC50 (functional) = 0.046 ug ml-1 Cytotoxicity against human KB cells by MTT assay ChEMBL. 16480866
IC50 (functional) = 0.1 ug ml-1 Inhibitory concentration against human T-cell leukemic cell line (CRFF-CEM) in vitro ChEMBL. 2918516
IC50 (functional) = 0.1 ug ml-1 Inhibition against CRFF-CEM-T-Cell leukemic cell line ChEMBL. 2769688
IC50 (functional) = 0.22 ug ml-1 Cytotoxicity against human MCF7 cells by clonogenic assay ChEMBL. 16480866
IC50 (functional) = 0.46 ug ml-1 Cytotoxicity against human KB cells by clonogenic assay ChEMBL. 16480866
IC50 (functional) = 0.52 ug ml-1 Cytotoxicity against human Colo320DM cells by MTT assay ChEMBL. 16480866
IC50 (functional) = 1.15 ug ml-1 Cytotoxicity against human PA1 cells by clonogenic assay ChEMBL. 16480866
IC50 (functional) = 1.45 ug ml-1 Cytotoxicity against human WRL68 cells by MTT assay ChEMBL. 16480866
IC50 (functional) = 1.6 ug ml-1 Cytotoxicity against human Colo320DM cells by clonogenic assay ChEMBL. 16480866
IC50 (functional) = 2.6 ug ml-1 Cytotoxicity against human WRL68 cells by clonogenic assay ChEMBL. 16480866
IC50 (functional) = 0.0012 uM Concentration required for growth inhibition of human lymphoblastic leukemic cell line (CCRF-CEM) was determined ChEMBL. 15324894
IC50 (functional) = 0.004 uM Cytotoxicity against human small-cell lung cancer (SCLC) ChEMBL. 8258835
IC50 (functional) = 0.004 uM Intrinsic cytotoxic activity of the compound against wild type HCT116 cell line ChEMBL. 15546712
IC50 (functional) = 0.005 uM Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP) ChEMBL. 8258835
IC50 (functional) = 0.0087 uM Concentration required for growth inhibition of human HCT-116 colon tumor cell line (CCRF-CEM) was determined ChEMBL. 15324894
IC50 (functional) = 0.0099 uM Concentration required for growth inhibition of human lung carcinoma cell line (CCRF-CEM) was determined ChEMBL. 15324894
IC50 (functional) = 0.011 uM Inhibition of the growth of MDA-MB 231 human breast cancer cells ChEMBL. 9357519
IC50 (functional) = 0.02 uM Concentration required for growth inhibition of taxol resistant human lymphoblastic leukemic cell line (CCRF-CEM/taxol) was determined ChEMBL. 15324894
IC50 (functional) = 0.54 uM Concentration required for growth inhibition of vinblastine resistant human lymphoblastic leukemic cell line (CCRF-CEM/VBL) was determined ChEMBL. 15324894
IC50 (functional) = 0.6 uM Concentration of compound required to inhibit tubulin polymerization (Microtubule assembly) was determined by the turbidity formation after 20 min of incubation ChEMBL. 12372531
IC50 (functional) = 0.7 uM Inhibition of tubulin polymerization using isolated calf brain ChEMBL. 9357519
IC50 (functional) = 1 uM Inhibition of bovine brain microtubule polymerization ChEMBL. 11814821
IC50 (functional) = 1 uM Inhibition of tubulin polymerization interacting at the colchicine binding site. ChEMBL. 15686910
IC50 (binding) = 34 uM Concentration required for 50% inhibition of the compound at binding site of human P-Glycoprotein (P-gp) in one-affinity model ChEMBL. 12477351
ILS (functional) = 14.6 % Evaluation of Survival of mice upon intraperitoneal injection of VBL at a concentration of 0.2 mg/kg ChEMBL. 8544183
ILS (functional) ~ 50 % Compound was tested for % increase in life span of vincristine resistant P388 tumor ChEMBL. No reference
ILS (functional) = 89 % Evaluation of ILS percentage of mice upon intraperitoneal injection of VBL at a concentration of 0.2 mg/kg ChEMBL. 8544183
ILS (functional) ~ 100 % Compound was tested for % increase in life span of P388 tumor ChEMBL. No reference
Inhibition (functional) = 8 Fold increase of the inhibition of the compound in presence of Reserpine ChEMBL. 15012986
Inhibition (functional) = 64 % Inhibition of colchicine binding to tubulin ChEMBL. 9357519
Ki (binding) = 0.1 uM High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model ChEMBL. 12477351
Ki (binding) = 1.3 uM Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model ChEMBL. 12477351
Ki (binding) = 77 uM Inhibitory activity of the compound against Monoamine oxidase B isolated from beef liver mitochondria was determined ChEMBL. 2362262
Ki (binding) > 100 uM Binding constant at colchicine site of bovine brain tubulin ChEMBL. 11814821
LC50 (functional) < 0.00025 uM Tested for the concentration required to reduce the viability of leukemia cells by 50% against cell grwoth of T cell leukemia cell line MOLT-4 using MTT assay ChEMBL. 11858989
LC50 (functional) = 0.00025 uM Tested for the concentration required to reduce the viability of leukemia cells by 50% against cell growth of HuT78 T lymphoma using MTT assay ChEMBL. 11858989
LC50 (functional) < 0.00025 uM Tested for the concentration required to reduce the viability of leukemia cells by 50% against cell growth of K562 chronic myeloid leukemia using MTT assay ChEMBL. 11858989
LC50 (functional) = 0.00151 uM Tested for the concentration required to reduce the viability of leukemia cells by 50% against cell growth of HL60 acute myeloid leukemia using MTT assay ChEMBL. 11858989
LC50 (functional) = 0.00328 uM Tested for the concentration required to reduce the viability of leukemia cells by 50% against cell growth of RPMI8226 multiple myeloma using MTT assay ChEMBL. 11858989
LC50 (functional) = 0.00573 uM Tested for the concentration required to reduce the viability of leukemia cells by 50% against cell growth of T cell leukemia cell line CCRF-CEM using MTT assay ChEMBL. 11858989
Log CR (functional) = 1.28 Effect on cross resistance of CCRF-CEM cells resistant to vincristine. ChEMBL. 2362268
Log CR (functional) = 1.46 Effect on cross resistance of CHO cells resistant to colchicine (CHRC5) ChEMBL. 2362268
Log CR (functional) = 2.38 Effect on cross resistance of chinese hamster cells resistant to Actinomycin D. ChEMBL. 2362268
Log kill (functional) < 0.7 In vivo activity against transplanted Mam-16/C/Adr tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Mam-16/C/ Taxol tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted colon-51 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Panc-02 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Panc-03 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Mam-17 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Mam-17/Adr tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted colon-26 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Mel-B16 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against transplanted Squam lung-LC12 tumors of mice ChEMBL. 11356111
Log kill (functional) < 0.7 In vivo activity against iv transplanted AML Leukemia 1498 tumors of mice ChEMBL. 11356111
Log kill (functional) = 1.9 In vivo activity against transplanted Mam-16/C tumors of mice ChEMBL. 11356111
Log kill (functional) = 1.9 In vivo activity against iv transplanted Leukemia L1210 tumors of mice ChEMBL. 11356111
Log kill (functional) = 2.8 In vivo activity against transplanted colon-38 tumors of mice ChEMBL. 11356111
logD (ADMET) = 3.69 Partition coefficient (logD7.4) ChEMBL. 2362268
Permeability (functional) 0 permeability of the compound in Caco-2 cells; yes ChEMBL. 10753475
Permeability (functional) 0 Efflux of the compound in Caco-2 cells; yes ChEMBL. 10753475
Permeability (functional) = 1.54 *10e6 Absorptive transport of the compound in Caco-2 cells in comparison to metoprolol ChEMBL. 10753475
Permeability (functional) = 12.5 *10e6 Secretory Transport of the compound in Caco-2 cells in comparison to metoprolol ChEMBL. 10753475
pKa = 5.4 Apparent value (pKa) of the compound calculated with ACD/pKa (experimental pKa value) ChEMBL. 12477351
pKa = 5.96 Calculated dissociation constant (pKa, calculated with ACD/pKa) ChEMBL. 12477351
pKa = 7.4 Apparent value (pKa) of the compound calculated with ACD/pKa (experimental pKa value) ChEMBL. 12477351
pKa = 7.59 Calculated dissociation constant (pKa, calculated with ACD/pKa) ChEMBL. 12477351
Ratio (functional) = 19.9 Ratio between IC50 value of DOX/R and WP159/R was determined ChEMBL. No reference
Reduction (functional) = 0 % Approximate percentage for level of inhibition of cell growth in presence and absence of inhibitor (Value of drug + GG918 / Value of drug) ChEMBL. 15012986
Reduction (functional) ~ 88 % Approximate percentage for level of inhibition of cell growth in presence and absence of inhibitor (Value of drug + Verapamil / Value of drug) ChEMBL. 15012986
Reduction (functional) ~ 94 % Percentage inhibition of cell growth in the presence of compound and in the absence of GG198 in H69/LX4 cells with clofazimine MDR inhibitor ChEMBL. 15012986
Reduction (functional) ~ 95 % Approximate percentage for level of inhibition of cell growth in presence and absence of inhibitor (Value of drug + GG918 / Value of drug) ChEMBL. 15012986
Reduction (functional) ~ 95 % Approximate percentage for level of inhibition of cell growth in presence and absence of inhibitor (Value of drug + alpha Tochoferol / Value of drug) ChEMBL. 15012986
Reduction (functional) > 99 % Percent colony reduction in cell growth in EBV-positive nasopharyngeal cell lines after administration of 6.0 ug/mL dose ChEMBL. 6685770
Relative IC50 (functional) = 0.2 nM Cytotoxic activity was evaluated against P388/ADR + reserpine cells ChEMBL. 8632413
Relative IC50 (functional) = 0.5 nM Cytotoxic activity was evaluated against MCF-7/ADR+Reserpine cells ChEMBL. 8632413
Relative IC50 (functional) = 1 nM Cytotoxic activity was evaluated against KB3-1 cells ChEMBL. 8632413
Relative IC50 (functional) = 1 nM Cytotoxic activity was evaluated against MCF-7 cells ChEMBL. 8632413
Relative IC50 (functional) = 1 nM Cytotoxic Activity of the compound was evaluated against P388D1 cells ChEMBL. 8632413
Relative IC50 (functional) = 1.3 nM Cytotoxic activity was evaluated against KBV-1 cells in presence of reserpine ChEMBL. 8632413
Relative IC50 (functional) = 19 nM Cytotoxic activity was evaluated against P388D1/ADR cells ChEMBL. 8632413
Relative IC50 (functional) = 2000 nM Cytotoxic activity was evaluated against KBV-1 cells ChEMBL. 8632413
Relative IC50 (functional) = 17500 nM Cytotoxic activity was evaluated against MCF-7/ADR cells ChEMBL. 8632413
Survival (functional) < 0.01 EBV-positive nasopharyngeal colony count obtained from the examination of uniform plate surface areas after a dose of 6.0 ug/mL ChEMBL. 6685770
Survival days (functional) = 11 In vivo evaluation for the inhibitory activity against drug sensitive P388 cells (P388/S) cells bearing mice at dose 0.2 mg/kg ChEMBL. 8544183
Survival days (functional) = 15.5 In vivo evaluation for the inhibitory activity against drug sensitive P388 cells (P388/ADR) cells bearing mice at a concentration of 0.2 mg/kg ChEMBL. 8544183
T/C (functional) = 140 % The ratio of survival time for treated divided by survival time of control x 100 at a dose of 0.2 mg/kg in L1210 leukemia cells ChEMBL. 2362275
T/C (functional) = 180 % The ratio of survival time for treated divided by survival time of control x 100 at a dose of 0.2 mg/kg in B16 melanoma cells ChEMBL. 2362275
TGI (functional) < 0.00025 uM Tested for the inhibitory concentration against cell growth of Tcell leukemic cell line MOLT-4 using MTT assay ChEMBL. 11858989
TGI (functional) < 0.00025 uM Tested for the inhibitory concentration against cell growth of HuT78 T lymphoma using MTT assay ChEMBL. 11858989
TGI (functional) < 0.00025 uM Tested for the inhibitory concentration against cell growth of K562 chronic myeloid leukemia using MTT assay ChEMBL. 11858989
TGI (functional) = 0.00025 uM Tested for the inhibitory concentration against cell growth of HL60 acute myeloid leukemia using MTT assay ChEMBL. 11858989
TGI (functional) = 0.0008 uM Tested for the inhibitory concentration against cell growth of RPM18226 multiple myeloma using MTT assay ChEMBL. 11858989
TGI (functional) = 0.00191 uM Tested for the inhibitory concentration against cell growth of Tcell leukemic cell line CCRF-CEM using MTT assay ChEMBL. 11858989

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 26523419

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
microtubule polymerization (GO:0046785) decreased (PATO:0000468) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin and in live cells; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied