Detailed information for compound 276801

Basic information

Technical information
  • TDR Targets ID: 276801
  • Name: N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hyd roxy-6-methoxy-5-methyl-3-propylbenzamide
  • MW: 334.453 | Formula: C19H30N2O3
  • H donors: 2 H acceptors: 2 LogP: 4.03 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCc1cc(C)c(c(c1O)C(=O)NC[C@@H]1CCCN1CC)OC
  • InChi: 1S/C19H30N2O3/c1-5-8-14-11-13(3)18(24-4)16(17(14)22)19(23)20-12-15-9-7-10-21(15)6-2/h11,15,22H,5-10,12H2,1-4H3,(H,20,23)/t15-/m0/s1
  • InChiKey: BHRRLHBGKIMHGD-HNNXBMFYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxy-5-methyl-3-propyl-benzamide
  • N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxy-5-methyl-3-propylbenzamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Dopamine receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Dopamine receptor   475 aa 405 aa 33.3 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Dopamine receptor   475 aa 398 aa 34.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0076 0.3926 1
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0011 0.0054 0.0139
Brugia malayi proteasome subunit beta type 2 0.0034 0.1427 0.1427
Onchocerca volvulus 0.0026 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Toxoplasma gondii heat shock protein hslv, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine protein kinase Src42A 0.0026 0.0964 0.2457
Echinococcus multilocularis epidermal growth factor receptor 0.0026 0.0964 0.2457
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0011 0.0054 0.0054
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/INSR protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Plasmodium vivax proteasome subunit beta type-3, putative 0.0011 0.0054 0.0139
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0011 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Brugia malayi Guanylyl cyclase protein 23 0.0026 0.0964 0.0964
Brugia malayi Proteasome A-type and B-type family protein 0.0011 0.0054 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine protein kinase shark 0.0026 0.0964 0.2457
Brugia malayi bone morphogenetic protein type 1 receptor 0.0026 0.0964 0.0964
Onchocerca volvulus 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0011 0.0054 0.0139
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0034 0.1427 0.3635
Echinococcus granulosus tyrosine protein kinase Src64B 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Giardia lamblia Kinase, NEK 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0026 0.0964 0.2457
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0011 0.0054 0.0139
Entamoeba histolytica receptor protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0011 0.0054 0.0139
Giardia lamblia Kinase 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0011 0.0054 0.0139
Leishmania major hypothetical protein, conserved 0.0026 0.0964 0.235
Entamoeba histolytica serine/threonine kinase, putative 0.0026 0.0964 0.2457
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0011 0.0054 0.0139
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0011 0.0054 0.0139
Onchocerca volvulus 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0026 0.0964 0.2457
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0011 0.0054 0.0139
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0011 0.0054 0.0139
Plasmodium falciparum protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0011 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica serine/threonine kinase, putative 0.0026 0.0964 0.2457
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0034 0.1427 0.3635
Brugia malayi Appr-1-p processing enzyme family protein 0.0015 0.0325 0.0325
Brugia malayi 20S proteasome alpha5 subunit 0.0011 0.0054 0.0054
Schistosoma mansoni hypothetical protein 0.0015 0.0325 0.0827
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosin kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica serine/threonine kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0011 0.0054 0.0139
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus multilocularis raf serine:threonine protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Schistosoma mansoni serine/threonine RGC 0.0026 0.0964 0.2457
Echinococcus granulosus activin receptor type 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Echinococcus granulosus protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Trypanosoma brucei protein kinase, putative 0.0026 0.0964 0.2457
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica serine/threonine kinase, putative 0.0026 0.0964 0.2457
Echinococcus multilocularis heat shock protein 70 0.0026 0.0964 0.2457
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase Abl 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/ROR protein kinase 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Schistosoma mansoni ephrin receptor 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) hypothetical protein 0.0178 1 1
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0325 0.0827
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0011 0.0054 0.0139
Brugia malayi integrin-linked kinase 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0011 0.0054 0.0139
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Brugia malayi C-terminal src kinase protein 1 0.0026 0.0964 0.0964
Trichomonas vaginalis protein kinase atn1, putative 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0011 0.0054 0.0139
Plasmodium falciparum protein kinase, putative 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Plasmodium falciparum tyrosine kinase-like protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Echinococcus granulosus Proteasome subunit alpha beta 0.0011 0.0054 0.0139
Mycobacterium ulcerans lipoprotein LppD 0.0015 0.0325 0.0827
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Echinococcus multilocularis MACRO domain containing protein 2 0.0015 0.0325 0.0827
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0011 0.0054 0.0139
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0011 0.0054 0.0139
Brugia malayi proteasome subunit alpha type 2 0.0011 0.0054 0.0054
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Onchocerca volvulus Tyrosine kinase homolog 0.0026 0.0964 0.0964
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus granulosus integrin linked protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus proteasome subunit alpha type 6 0.0011 0.0054 0.0139
Chlamydia trachomatis DNA ligase 0.001 0 0.5
Echinococcus granulosus tyrosine protein kinase pr2 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.1427 0.3635
Toxoplasma gondii proteasome beta subunit 0.0011 0.0054 0.0139
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0011 0.0054 0.0139
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/ALK protein kinase 0.0026 0.0964 0.0964
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0011 0.0054 0.0139
Brugia malayi Tyrosine-protein kinase PR2 0.0026 0.0964 0.0964
Brugia malayi ephrin receptor 1 precursor 0.0026 0.0964 0.0964
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus granulosus Proteasome subunit alpha type 7 0.0011 0.0054 0.0139
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Trypanosoma brucei Pseudokinase, putative 0.0026 0.0964 0.2457
Brugia malayi Proteasome subunit alpha type 1 0.0011 0.0054 0.0054
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus granulosus natriuretic peptide receptor 1 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0011 0.0054 0.0139
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0011 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Brugia malayi hypothetical protein 0.0026 0.0964 0.0964
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0011 0.0054 0.0139
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0026 0.0964 0.2457
Plasmodium falciparum proteasome subunit beta type-4 0.0011 0.0054 0.0139
Echinococcus granulosus MACRO domain containing protein 2 0.0015 0.0325 0.0827
Echinococcus multilocularis tyrosine kinase 0.0026 0.0964 0.2457
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0964 0.0964
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0026 0.0964 0.0964
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase HCK 0.0026 0.0964 0.2457
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0026 0.0964 0.0964
Leishmania major proteasome beta 2 subunit, putative 0.0034 0.1427 0.3546
Echinococcus multilocularis tyrosine protein kinase Blk 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0034 0.1427 0.3635
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0011 0.0054 0.0139
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0026 0.0964 0.2457
Echinococcus granulosus proteasome subunit beta type 6 0.0011 0.0054 0.0139
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Brugia malayi SH2 domain containing protein 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis epidermal growth factor receptor 0.0026 0.0964 0.2457
Echinococcus multilocularis ephrin type A receptor 4 A 0.0026 0.0964 0.2457
Echinococcus granulosus proteasome subunit beta type 7 0.0011 0.0054 0.0139
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0011 0.0054 0.0139
Echinococcus granulosus proteasome prosome macropain 0.0076 0.3926 1
Echinococcus granulosus subfamily T1A non peptidase ue 0.0011 0.0054 0.0139
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Loa Loa (eye worm) TK/CSK protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0011 0.0054 0.0139
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0015 0.0325 0.0827
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0026 0.0964 0.2457
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0076 0.3926 1
Trypanosoma cruzi protein kinase, putative 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0011 0.0054 0.0054
Plasmodium vivax proteasome subunit beta type-4, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase Srms 0.0026 0.0964 0.2457
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0011 0.0054 0.0139
Treponema pallidum DNA ligase (lig) 0.001 0 0.5
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Echinococcus multilocularis MACRO domain containing protein 2 0.0015 0.0325 0.0827
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0026 0.0964 0.2457
Entamoeba histolytica cysteine surface protein, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Echinococcus granulosus MACRO domain containing protein 2 0.0015 0.0325 0.0827
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0011 0.0054 0.0139
Brugia malayi Proteasome subunit alpha type 7-1 0.0011 0.0054 0.0054
Echinococcus granulosus protein tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0026 0.0964 0.2457
Echinococcus multilocularis proteasome subunit alpha type 6 0.0011 0.0054 0.0139
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0034 0.1427 0.3635
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0015 0.0325 0.0827
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0011 0.0054 0.0139
Plasmodium vivax proteasome subunit beta type-5, putative 0.0076 0.3926 1
Echinococcus multilocularis proteasome subunit alpha type 2 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trypanosoma cruzi Macro domain containing protein, putative 0.0015 0.0325 0.0827
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0011 0.0054 0.0139
Giardia lamblia Protein 21.1 0.0026 0.0964 0.2457
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/ABL protein kinase 0.0026 0.0964 0.0964
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus raf serine:threonine protein kinase 0.0026 0.0964 0.2457
Brugia malayi Proteasome A-type and B-type family protein 0.0011 0.0054 0.0054
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus multilocularis receptor type guanylyl cyclase 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0011 0.0054 0.0139
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0011 0.0054 1
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Echinococcus multilocularis proteasome subunit beta type 6 0.0011 0.0054 0.0139
Echinococcus multilocularis c src tyrosine kinase 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0026 0.0964 0.0964
Plasmodium vivax protein kinase, putative 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis proteasome (prosome, macropain) 0.0076 0.3926 1
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0325 0.0827
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0011 0.0054 0.0139
Toxoplasma gondii proteasome subunit 0.0011 0.0054 0.0139
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0026 0.0964 0.2457
Echinococcus multilocularis activated cdc42 kinase 1 0.0026 0.0964 0.2457
Echinococcus granulosus c src tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0011 0.0054 0.0054
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0011 0.0054 0.0139
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0026 0.0964 0.0964
Echinococcus granulosus tyrosine protein kinase csk 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0011 0.0054 0.0139
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0011 0.0054 0.0139
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0034 0.1427 0.3635
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Plasmodium vivax tyrosine kinase-like protein, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus epidermal growth factor receptor 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0034 0.1427 0.3635
Echinococcus granulosus proteasome subunit alpha type 2 0.0011 0.0054 0.0139
Echinococcus granulosus retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis activin receptor type 0.0026 0.0964 0.2457
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Trypanosoma brucei Flagellum attachment zone protein 20 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome beta 6 subunit 0.0011 0.0054 0.0139
Giardia lamblia 20S proteasome alpha subunit 6 0.0011 0.0054 0.0139
Plasmodium vivax proteasome subunit beta type-7, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Plasmodium vivax tyrosine kinase-like protein, putative 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Plasmodium falciparum proteasome subunit beta type-5 0.0076 0.3926 1
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0325 0.0827
Giardia lamblia 20S proteasome alpha subunit 4 0.0011 0.0054 0.0139
Giardia lamblia Protein LRP16 0.0015 0.0325 0.0827
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0026 0.0964 0.2457
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0011 0.0054 0.0139
Plasmodium vivax proteasome subunit beta type-6, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) proteasome subunit beta type 1 0.0011 0.0054 0.0054
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0076 0.3926 1
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Toxoplasma gondii proteasome subunit alpha1, putative 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine protein kinase csk 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine protein kinase HCK 0.0026 0.0964 0.2457
Loa Loa (eye worm) serine/threonine protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Toxoplasma gondii protein kinase 0.0026 0.0964 0.2457
Brugia malayi proteasome subunit beta type 1 0.0011 0.0054 0.0054
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Giardia lamblia 20S proteasome alpha subunit 5 0.0011 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/EPH protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0076 0.3926 0.3926
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0034 0.1427 0.3635
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus ephrin type A receptor 4 A 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0076 0.3926 1
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Plasmodium vivax proteasome subunit beta type-2, putative 0.0034 0.1427 0.3635
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Giardia lamblia Proteasome subunit beta type 3 0.0011 0.0054 0.0139
Echinococcus granulosus epidermal growth factor receptor 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni hypothetical protein 0.0015 0.0325 0.0827
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0026 0.0964 0.0964
Echinococcus granulosus tyrosine kinase 0.0026 0.0964 0.2457
Brugia malayi proteasome subunit alpha type 1 0.0011 0.0054 0.0054
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Giardia lamblia 20S proteasome alpha subunit 2 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) TK/Met protein kinase 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0026 0.0964 0.2457
Plasmodium falciparum Appr-1-p processing domain protein 0.0015 0.0325 0.0827
Trichomonas vaginalis TK family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Plasmodium falciparum tyrosine kinase-like protein 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0076 0.3926 1
Toxoplasma gondii protein kinase domain-containing protein 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0011 0.0054 0.0139
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus granulosus activated cdc42 kinase 1 0.0026 0.0964 0.2457
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0026 0.0964 0.0964
Loa Loa (eye worm) PAS-3 protein 0.0011 0.0054 0.0054
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Mycobacterium ulcerans proteasome PrcB 0.0076 0.3926 1
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0015 0.0325 0.0827
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0011 0.0054 0.0139
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/DDR protein kinase 0.0026 0.0964 0.0964
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0026 0.0964 0.2457
Brugia malayi protein-tyrosine kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) proteasome subunit beta type 3 0.0011 0.0054 0.0054
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Toxoplasma gondii macro domain-containing protein 0.0015 0.0325 0.0827
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Leishmania major protein kinase, putative 0.0026 0.0964 0.235
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Echinococcus multilocularis transfer RNA-Thr 0.0026 0.0964 0.2457
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0011 0.0054 0.0139
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Brugia malayi proteasome subunit beta type 3 0.0011 0.0054 0.0054
Echinococcus multilocularis insulin receptor 0.0026 0.0964 0.2457
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase shark 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome beta 7 subunit 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Brugia malayi hypothetical protein 0.0026 0.0964 0.0964
Brugia malayi Raf kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0026 0.0964 0.0964
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/EGFR protein kinase 0.0026 0.0964 0.0964
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0011 0.0054 0.0139
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase ABL1 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus multilocularis FL cytokine receptor 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0026 0.0964 0.2457
Brugia malayi Receptor family ligand binding region containing protein 0.0026 0.0964 0.0964
Brugia malayi SH2 domain containing protein 0.0026 0.0964 0.0964
Echinococcus multilocularis proteasome subunit beta type 7 0.0011 0.0054 0.0139
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis protein KINase family member (kin 25) 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0011 0.0054 0.0139
Onchocerca volvulus Notchless protein homolog 0.0011 0.0054 0.0054
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Plasmodium vivax proteasome subunit beta type-1, putative 0.0011 0.0054 0.0139
Mycobacterium ulcerans proteasome PrcA 0.0011 0.0054 0.0139
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0011 0.0054 0.0139
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0076 0.3926 1
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0011 0.0054 0.0139
Brugia malayi SRC-1 0.0026 0.0964 0.0964
Loa Loa (eye worm) protein kinase domain-containing protein 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus insulin receptor 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Echinococcus granulosus retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Brugia malayi proteasome subunit alpha type 4 0.0011 0.0054 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0011 0.0054 0.0139
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0011 0.0054 0.0139
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0034 0.1427 0.3635
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus granulosus activated cdc42 kinase 1 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0026 0.0964 0.2457
Giardia lamblia 20S proteasome alpha subunit 1 0.0011 0.0054 0.0139
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Trichomonas vaginalis STE family protein kinase 0.0026 0.0964 0.2457
Trypanosoma cruzi protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosin kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Toxoplasma gondii proteasome subunit alpha type, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0011 0.0054 0.0054
Entamoeba histolytica serine/threonine kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0076 0.3926 1
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis integrin linked protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase csk 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Onchocerca volvulus 0.0026 0.0964 0.0964
Echinococcus granulosus retinal guanylyl cyclase 2 0.0026 0.0964 0.2457
Giardia lamblia 20S proteasome alpha subunit 3 0.0011 0.0054 0.0139
Entamoeba histolytica serine/threonine kinase, putative 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Schistosoma mansoni ephrin receptor 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0011 0.0054 0.0054
Brugia malayi proteasome subunit alpha type 3 0.0011 0.0054 0.0054
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0026 0.0964 0.2457
Echinococcus granulosus fibroblast growth factor receptor 4 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0011 0.0054 0.0054
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Leishmania major protein kinase, putative 0.0026 0.0964 0.235
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni hypothetical protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/RYK protein kinase 0.0026 0.0964 0.0964
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0011 0.0054 0.0054
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0011 0.0054 0.0139
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0325 0.0827
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0011 0.0054 0.0139
Echinococcus granulosus receptor type guanylyl cyclase 0.0026 0.0964 0.2457
Entamoeba histolytica ankyrin repeat protein 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Srms 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0011 0.0054 0.0139
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0011 0.0054 0.0139
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Leishmania major proteasome beta 5 subunit, putative 0.0076 0.3926 1
Brugia malayi Proteasome A-type and B-type family protein 0.0076 0.3926 0.3926
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis natriuretic peptide receptor 1 0.0026 0.0964 0.2457
Trichomonas vaginalis protein tyrosine kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0011 0.0054 0.0139
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Echinococcus multilocularis protein tyrosine kinase 0.0026 0.0964 0.2457
Schistosoma mansoni protein tyrosine kinase 0.0026 0.0964 0.2457
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0011 0.0054 0.0139
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0964 0.0964
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0076 0.3926 1
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Trichomonas vaginalis CAMK family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0011 0.0054 0.0139
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosin kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0011 0.0054 0.0139
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0964 0.2457
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0011 0.0054 0.0139
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Brugia malayi Proteasome A-type and B-type family protein 0.0011 0.0054 0.0054
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Trypanosoma brucei Macro domain containing protein, putative 0.0015 0.0325 0.0827
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0011 0.0054 0.0054
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0011 0.0054 0.0054
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0026 0.0964 0.2457
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0011 0.0054 0.0139
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Onchocerca volvulus 0.0026 0.0964 0.0964
Echinococcus granulosus kinase suppressor of Ras 1 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase csk 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0076 0.3926 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0964 0.0964
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0964 0.2457
Toxoplasma gondii proteasome subunit beta type, putative 0.0076 0.3926 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0026 0.0964 0.0964
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0026 0.0964 0.2457
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Mycobacterium tuberculosis Possible lipoprotein LppD 0.0015 0.0325 0.0698
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0034 0.1427 0.3635
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0011 0.0054 0.0139
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0026 0.0964 0.0964
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase csk 0.0026 0.0964 0.2457
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase, putative 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0011 0.0054 0.0139
Entamoeba histolytica tyrosin kinase, putative 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine kinase 0.0026 0.0964 0.2457
Trypanosoma cruzi 20S proteasome subunit 0.0034 0.1427 0.3635
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0011 0.0054 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Echinococcus multilocularis protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Toxoplasma gondii peptidase, T1 family protein 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase csk 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Blk 0.0026 0.0964 0.2457
Entamoeba histolytica hypothetical protein 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica tyrosine kinase, putative 0.0026 0.0964 0.2457
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0026 0.0964 0.0964
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Giardia lamblia Proteasome subunit beta type 1 0.0011 0.0054 0.0139
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0011 0.0054 0.0139
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0026 0.0964 0.2457
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0026 0.0964 0.0964
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.1427 0.3635
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0011 0.0054 0.0139
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0011 0.0054 0.0139
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Trypanosoma brucei proteasome alpha 7 subunit 0.0011 0.0054 0.0139
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase Lyn 0.0026 0.0964 0.2457
Echinococcus granulosus tyrosine protein kinase csk 0.0026 0.0964 0.2457
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0026 0.0964 0.2457
Brugia malayi proteasome subunit alpha type 6 0.0011 0.0054 0.0054
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0011 0.0054 0.0139
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK protein kinase 0.0026 0.0964 0.0964
Brugia malayi Tyrosine-protein kinase abl-1 0.0026 0.0964 0.0964
Loa Loa (eye worm) proteasome subunit beta type 2 0.0034 0.1427 0.1427
Giardia lamblia 20S proteasome alpha subunit 7 0.0011 0.0054 0.0139
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0011 0.0054 0.0139
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0011 0.0054 0.0139
Trypanosoma cruzi Macro domain containing protein, putative 0.0015 0.0325 0.0827
Loa Loa (eye worm) SRC-1 0.0026 0.0964 0.0964
Brugia malayi Furin-like cysteine rich region family protein 0.0026 0.0964 0.0964
Loa Loa (eye worm) TK/FAK protein kinase 0.0026 0.0964 0.0964
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/ACK protein kinase 0.0026 0.0964 0.0964
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Toxoplasma gondii STE kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Entamoeba histolytica receptor protein kinase, putative 0.0026 0.0964 0.2457
Giardia lamblia Proteasome subunit beta type 2 0.0034 0.1427 0.3635
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Giardia lamblia Kinase, NEK 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis kinase suppressor of Ras 1 0.0026 0.0964 0.2457
Brugia malayi Protein kinase domain containing protein 0.0026 0.0964 0.0964
Onchocerca volvulus 0.0026 0.0964 0.0964
Onchocerca volvulus 0.0026 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Plasmodium falciparum protein kinase, putative 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase pr2 0.0026 0.0964 0.2457
Schistosoma mansoni protein kinase 0.0026 0.0964 0.2457
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0026 0.0964 0.2457
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0011 0.0054 0.0139
Entamoeba histolytica protein kinase domain containing protein 0.0026 0.0964 0.2457
Entamoeba histolytica ankyrin repeat protein 0.0026 0.0964 0.2457
Brugia malayi hypothetical protein 0.0026 0.0964 0.0964
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0178 1 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0325 0.0325
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0011 0.0054 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0011 0.0054 0.0139
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0026 0.0964 0.2457
Trichomonas vaginalis TKL family protein kinase 0.0026 0.0964 0.2457
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0026 0.0964 0.2457
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0964 0.0964
Echinococcus granulosus proteasome subunit beta t family 0.0011 0.0054 0.0139
Schistosoma mansoni tyrosine kinase 0.0026 0.0964 0.2457
Onchocerca volvulus 0.0026 0.0964 0.0964

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.005 uM Antidopamine activity in vitro by ability to displace [3H]-spiperone from rat brain striatal preparations. ChEMBL. 3941414
IC50 (binding) = 0.005 uM Antidopamine activity in vitro by ability to displace [3H]-spiperone from rat brain striatal preparations. ChEMBL. 3941414

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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