Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | ABC transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Echinococcus granulosus | subfamily T1A non peptidase ue | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit alpha 3 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | 20S proteasome subunit alpha 6 | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Loa Loa (eye worm) | proteasome subunit alpha type 1 | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0024 | 0.1258 | 0.1258 |
Plasmodium falciparum | proteasome subunit beta type-7, putative | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | 20S proteasome alpha subunit 4 | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit beta type 3, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | multidrug resistance protein 1 | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1238 | 0.1238 |
Leishmania major | hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome subunit alpha type 2 | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Mycobacterium ulcerans | proteasome PrcB | 0.0139 | 1 | 1 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0139 | 1 | 1 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.001 | 0.0224 | 0.0224 |
Leishmania major | p-glycoprotein | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0017 | 0.0705 | 0.0705 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit alpha type-3, putative | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit alpha type 5-2, putative | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome subunit alpha type 6 | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0139 | 1 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 1 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | proteasome subunit alpha type 5, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | ATP binding cassette sub family B | 0.0024 | 0.1238 | 0.1238 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma brucei | proteasome alpha 1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome subunit beta type 7 | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ABC transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Leishmania major | proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit alpha type, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | 20S proteasome subunit | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | proteasome subunit alpha type 4 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0024 | 0.1258 | 0.1258 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0139 | 1 | 1 |
Leishmania major | proteasome alpha 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | ATP-dependent protease subunit ClpQ | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome prosome macropain subunit alpha | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome subunit alpha type 2 | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | 5'partial|ATP binding cassette sub family B | 0.0024 | 0.1238 | 0.1238 |
Schistosoma mansoni | multidrug resistance protein | 0.0024 | 0.1258 | 0.1258 |
Toxoplasma gondii | heat shock protein hslv, putative | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome alpha 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit alpha type-5, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | multidrug resistance protein | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | proteasome subunit alpha type 6, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0139 | 1 | 1 |
Trypanosoma brucei | proteasome alpha 7 subunit | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0139 | 1 | 1 |
Brugia malayi | proteasome subunit alpha type 3 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0139 | 1 | 1 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0139 | 1 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | proteasome subunit alpha type 4, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0139 | 1 | 1 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0139 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0139 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | 20S proteasome alpha subunit 7 | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome subunit beta type 7 | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | proteasome subunit beta 4 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.0024 | 0.1258 | 0.1258 |
Giardia lamblia | Proteasome subunit beta type 7 precursor | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0017 | 0.0705 | 0.0705 |
Schistosoma mansoni | proteasome subunit alpha 2 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | proteasome subunit beta type 3 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 5, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | Proteasome, subunit alpha beta | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit beta type-4, putative | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome beta 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | 20S proteasome alpha5 subunit | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | proteasome catalytic subunit 2 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | subfamily T1A non peptidase ue | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0139 | 1 | 1 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit alpha type-7, putative | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | 20S proteasome alpha5 subunit | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 7, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome alpha 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit alpha type-4, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit alpha type-7, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0024 | 0.1258 | 0.1258 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | proteasome subunit alpha type 1, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Toxoplasma gondii | proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome subunit beta type 3 | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | 20S proteasome alpha subunit 3 | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit alpha 6 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | abcb9, putative | 0.0024 | 0.1258 | 0.1258 |
Toxoplasma gondii | proteasome subunit alpha type 1, putative | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | proteasome subunit alpha type 6 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 2-A, putative | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 4, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit beta type-3, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | Proteasome subunit A N-terminal signature/Proteasome subunit, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0139 | 1 | 1 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.001 | 0.0224 | 0.0224 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | 20S proteasome alpha subunit 1 | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1258 | 0.1258 |
Plasmodium vivax | proteasome subunit beta type-6, putative | 0.001 | 0.0224 | 0.0224 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.001 | 0.0224 | 1 |
Onchocerca volvulus | 0.0024 | 0.1258 | 1 | |
Toxoplasma gondii | peptidase, T1 family protein | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | 20S proteasome subunit alpha 6 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glycoprotein-5 | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | proteasome subunit beta type 6 precursor, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit beta type 7-B precursor, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glycoprotein-1 | 0.0024 | 0.1258 | 0.1258 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit alpha type-2, putative | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome subunit alpha type 3 | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | Proteasome subunit alpha type 7 | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | ABC transporter family protein | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome subunit alpha type 6 | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome beta subunit | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit beta type-6, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome subunit beta type 6 | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome subunit beta type 6 | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0017 | 0.0705 | 0.0705 |
Plasmodium falciparum | proteasome subunit alpha type-6, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0139 | 1 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0139 | 1 | 1 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | Proteasome subunit beta type 9 precursor | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit beta type 7 precursor, putative | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | smdr2 | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | proteasome subunit alpha 7 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome beta 7 subunit | 0.001 | 0.0224 | 0.0224 |
Mycobacterium tuberculosis | Probable transmembrane multidrug efflux pump | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma brucei | proteasome beta-1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | proteasome subunit beta type 1 | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome subunit alpha type 2 | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Brugia malayi | multidrug resistance protein 3 | 0.0024 | 0.1258 | 0.1258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Plasmodium falciparum | proteasome subunit beta type-3, putative | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | 20S proteasome alpha subunit 5 | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome beta-1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome beta 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | 20S proteasome alpha subunit 2 | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0017 | 0.0705 | 0.0705 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome subunit alpha type 7-1 | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0024 | 0.1258 | 0.1258 |
Leishmania major | proteasome beta 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome beta 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome prosome macropain subunit beta type | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0024 | 0.1258 | 0.1258 |
Giardia lamblia | Proteasome subunit beta type 4 precursor | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit alpha1, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Plasmodium vivax | proteasome subunit alpha type-6, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome subunit alpha type 6 | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | calcium-dependent protein kinase 2, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 7, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit beta type-4 | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | multidrug resistance protein 1, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome subunit alpha type-1, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0024 | 0.1258 | 0.1258 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0024 | 0.1258 | 0.1258 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ABC transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma brucei | proteasome alpha 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0024 | 0.1258 | 0.1258 |
Loa Loa (eye worm) | PAS-3 protein | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0139 | 1 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.0024 | 0.1258 | 0.1258 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit alpha type-2, putative | 0.001 | 0.0224 | 0.0224 |
Giardia lamblia | Proteasome subunit beta type 3 | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 3, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | ATP-dependent protease subunit HslV | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | Proteasome subunit alpha beta | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | Proteasome subunit alpha type 1 | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.001 | 0.0224 | 0.0224 |
Mycobacterium ulcerans | proteasome PrcA | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome beta 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.001 | 0.0224 | 0.0224 |
Chlamydia trachomatis | ABC transporter ATP binding protein/permease | 0.0024 | 0.1258 | 0.5 |
Brugia malayi | proteasome subunit alpha type 2 | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | multidrug resistance protein | 0.0024 | 0.1258 | 0.1258 |
Brugia malayi | proteasome subunit beta type 2 | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit alpha | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit alpha type-1, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Schistosoma mansoni | proteasome subunit alpha 4 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0024 | 0.1258 | 0.1258 |
Giardia lamblia | 20S proteasome alpha subunit 6 | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.001 | 0.0224 | 0.0224 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | abcb9, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | taga, putative | 0.0024 | 0.1258 | 0.1258 |
Trichomonas vaginalis | abcb9, putative | 0.0024 | 0.1258 | 0.1258 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.001 | 0.0224 | 0.0224 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.001 | 0.0224 | 0.0224 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma brucei | proteasome subunit alpha type-5, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome prosome macropain | 0.0139 | 1 | 1 |
Trypanosoma cruzi | ATP-dependent protease subunit HslV, putative | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome beta 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | ABC transporter, putative | 0.0024 | 0.1258 | 0.1258 |
Plasmodium falciparum | proteasome subunit alpha type-5, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0024 | 0.1258 | 0.1258 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Plasmodium vivax | proteasome subunit alpha type-4, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | ATP-dependent protease subunit ClpQ, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit alpha type-3, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome beta 7 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Echinococcus granulosus | proteasome subunit beta t family | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome alpha 3 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Toxoplasma gondii | 20S proteasome subunit beta 7, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | proteasome subunit alpha type 3, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.0024 | 0.1258 | 0.1258 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit beta type | 0.001 | 0.0224 | 0.0224 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trypanosoma cruzi | proteasome beta 2 subunit, putative | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | Proteasome subunit alpha type 7-1 | 0.001 | 0.0224 | 0.0224 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0024 | 0.1258 | 0.1258 |
Mycobacterium leprae | probable proteasome (alpha subunit) PrcA | 0.001 | 0.0224 | 0.0224 |
Plasmodium vivax | proteasome subunit beta type-7, putative | 0.001 | 0.0224 | 0.0224 |
Plasmodium falciparum | proteasome subunit alpha type-1, putative | 0.001 | 0.0224 | 0.0224 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.0024 | 0.1258 | 0.1258 |
Entamoeba histolytica | proteasome subunit beta Type 4 precursor, putative | 0.001 | 0.0224 | 0.0224 |
Brugia malayi | proteasome subunit alpha type 1 | 0.001 | 0.0224 | 0.0224 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
BWD (functional) | = -5.2 g | Body Weight Difference (BWD) of test animals administered with 400 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -5.2 g | Body Weight Difference (BWD) of test animals administered with 400 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -3 g | Body Weight Difference (BWD) of test animals administered with 200 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -3 g | Body Weight Difference (BWD) of test animals administered with 200 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -1.6 g | Body Weight Difference (BWD) of test animals administered with 100 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -1.6 g | Body Weight Difference (BWD) of test animals administered with 100 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -1.4 g | Body Weight Difference (BWD) of test animals administered with 50 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
BWD (functional) | = -1.4 g | Body Weight Difference (BWD) of test animals administered with 50 mg/kg compound is determined on day 5 for P388 tumor cells | ChEMBL. | 2909723 |
KE (functional) | = 0.17 | Ability of 100 mg/kg of compound to kill tumor cells in mice is expressed as the log of the tumor cell population at the onset of treatment minus the log of the tumor cell population at the end of treatment | ChEMBL. | 2909723 |
KE (functional) | = 0.6 | Ability of 50 mg/kg of compound to kill tumor cells in mice is expressed as the log of the tumor cell population at the onset of treatment minus the log of the tumor cell population at the end of treatment | ChEMBL. | 2909723 |
KE (functional) | = 1.46 | Ability of 200 mg/kg of compound to kill tumor cells in mice is expressed as the log of the tumor cell population at the onset of treatment minus the log of the tumor cell population at the end of treatment | ChEMBL. | 2909723 |
Survivors / animals tested (ADMET) | = 4 | Toxicity day evaluation was carried out on day 5 for animal dosed with 400 mg/kg compound; 4/5 | ChEMBL. | 2909723 |
Survivors / animals tested (ADMET) | = 5 | Toxicity day evaluation was carried out on day 5 for animal dosed with 200 mg/kg compound; 5/5 | ChEMBL. | 2909723 |
Survivors / animals tested (ADMET) | = 5 | Toxicity day evaluation was carried out on day 5 for animal dosed with 100 mg/kg compound; 5/5 | ChEMBL. | 2909723 |
Survivors / animals tested (ADMET) | = 5 | Toxicity day evaluation was carried out on day 5 for animal dosed with 50 mg/kg compound; 5/5 | ChEMBL. | 2909723 |
T/C (functional) | = 133 % | The percent of the median survival time of test mice compared to control mice is determined for mice administered with 100 mg/kg compound | ChEMBL. | 2909723 |
T/C (functional) | = 133 % | The percent of the median survival time of test mice compared to control mice is determined for mice administered with 100 mg/kg compound | ChEMBL. | 2909723 |
T/C (functional) | = 141 % | The percent of the median survival time of test mice compared to control mice is determined for mice administered with 50 mg/kg compound | ChEMBL. | 2909723 |
T/C (functional) | = 141 % | The percent of the median survival time of test mice compared to control mice is determined for mice administered with 50 mg/kg compound | ChEMBL. | 2909723 |
T/C (functional) | = 156 % | The percent of the median survival time of test mice compared to control mice is determined for mice administered with 200 mg/kg compound | ChEMBL. | 2909723 |
T/C (functional) | = 156 % | The percent of the median survival time of test mice compared to control mice is determined for mice administered with 200 mg/kg compound | ChEMBL. | 2909723 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.