Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.1828 | 0.2897 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0047 | 0.0398 | 0.1334 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0168 | 0.1879 | 0.2978 |
Leishmania major | NAD synthase, putative | 0.0241 | 0.2774 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0045 | 0.0368 | 0.0368 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.0916 | 0.0916 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Entamoeba histolytica | NAD synthetase, putative | 0.0241 | 0.2774 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0089 | 0.0916 | 0.2004 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.11 | 0.11 |
Brugia malayi | MAP kinase sur-1 | 0.0047 | 0.0398 | 0.0398 |
Onchocerca volvulus | 0.0829 | 1 | 1 | |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0045 | 0.0368 | 0.1224 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0096 | 0.1 | 0.1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0368 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0961 | 0.0961 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0045 | 0.0368 | 0.1258 |
Echinococcus multilocularis | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Trypanosoma brucei | protein kinase, putative | 0.0047 | 0.0398 | 0.1368 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0401 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0401 | 0.0401 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0051 | 0.044 | 0.1521 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0022 | 0.0094 | 0.0149 |
Onchocerca volvulus | 0.0047 | 0.0401 | 0.0401 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.044 | 0.044 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0093 | 0.0961 | 0.1522 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0045 | 0.0368 | 0.1258 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0368 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1 | 0.1 |
Brugia malayi | Muscleblind-like protein | 0.0093 | 0.0961 | 0.0961 |
Schistosoma mansoni | glutamine-dependent NAD(+) synthetase | 0.0241 | 0.2774 | 0.4395 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0022 | 0.0035 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0017 | 0.0033 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0178 | 0.2001 | 0.718 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0368 | 0.0368 |
Brugia malayi | Pre-SET motif family protein | 0.0047 | 0.0401 | 0.0401 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0017 | 0.0033 | 0.0033 |
Plasmodium vivax | GMP synthetase, putative | 0.0096 | 0.1 | 0.3555 |
Onchocerca volvulus | 0.0045 | 0.0368 | 0.0368 | |
Echinococcus granulosus | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0047 | 0.0398 | 0.1368 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0301 | 0.3517 | 0.5573 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0178 | 0.2001 | 0.2001 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0178 | 0.2001 | 0.2001 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0089 | 0.0916 | 0.1451 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0047 | 0.0401 | 0.1377 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1 | 0.1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Brugia malayi | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0178 | 0.2001 | 0.317 |
Loa Loa (eye worm) | carboxylesterase | 0.0528 | 0.6311 | 0.6311 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0047 | 0.0398 | 0.1334 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0.0398 | 0.083 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0045 | 0.0368 | 0.0583 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0024 | 0.0112 | 0.0112 |
Onchocerca volvulus | 0.0045 | 0.0368 | 0.0368 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0045 | 0.0368 | 0.0584 |
Giardia lamblia | NH3-dependent NAD+ synthetase | 0.0241 | 0.2774 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0051 | 0.044 | 0.0698 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.004 | 0.0316 | 0.0316 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0178 | 0.2001 | 0.2001 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0033 | 0.0039 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0089 | 0.0916 | 0.3222 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0017 | 0.0033 | 0.0052 |
Brugia malayi | Pre-SET motif family protein | 0.033 | 0.3878 | 0.3878 |
Schistosoma mansoni | jumonji domain containing protein | 0.0045 | 0.0368 | 0.0583 |
Echinococcus multilocularis | lamin | 0.0024 | 0.0112 | 0.0177 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0047 | 0.0398 | 0.1334 |
Plasmodium vivax | SET domain protein, putative | 0.0047 | 0.0401 | 0.1377 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0096 | 0.1 | 0.1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0168 | 0.1879 | 0.2978 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0045 | 0.0368 | 0.1258 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0.0398 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0106 | 0.0106 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0913 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.0916 | 0.0916 |
Echinococcus granulosus | neuropeptide s receptor | 0.0301 | 0.3517 | 0.5573 |
Schistosoma mansoni | phd/f-box containing protein | 0.0045 | 0.0368 | 0.0583 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0094 | 0.0149 |
Mycobacterium leprae | PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) | 0.0241 | 0.2774 | 0.5 |
Brugia malayi | GMP synthase | 0.0096 | 0.1 | 0.1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0089 | 0.0916 | 0.3222 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0913 |
Echinococcus multilocularis | neuroligin | 0.0089 | 0.0916 | 0.1451 |
Echinococcus granulosus | muscleblind protein | 0.0093 | 0.0961 | 0.1522 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0168 | 0.1879 | 0.2978 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.4059 | 0.4059 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0089 | 0.0916 | 0.1451 |
Echinococcus multilocularis | musashi | 0.0024 | 0.0112 | 0.0177 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0089 | 0.0916 | 0.3222 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0401 | 0.0635 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.004 | 0.0316 | 0.05 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0017 | 0.0033 | 0.0033 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0045 | 0.0368 | 0.1224 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0.0398 | 0.083 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0051 | 0.044 | 0.0698 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0047 | 0.0398 | 0.0631 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0046 | 0.038 | 0.0601 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0047 | 0.0401 | 0.0635 |
Plasmodium falciparum | GMP synthase [glutamine-hydrolyzing] | 0.0096 | 0.1 | 0.3555 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.0916 | 0.0916 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0401 | 0.0635 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1 | 0.1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0024 | 0.0112 | 0.0112 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0045 | 0.0368 | 0.0583 |
Echinococcus granulosus | carboxylesterase 5A | 0.0528 | 0.6311 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0528 | 0.6311 | 0.6311 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0047 | 0.0398 | 0.0398 |
Plasmodium falciparum | phd finger protein, putative | 0.0051 | 0.044 | 0.1521 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0368 | 0.1224 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.004 | 0.0316 | 0.05 |
Brugia malayi | jmjC domain containing protein | 0.0168 | 0.1879 | 0.1879 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.0094 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.11 | 0.11 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0368 | 0.0368 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0038 | 0.0283 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.1233 | 0.1233 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0047 | 0.0398 | 0.0631 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0178 | 0.2001 | 0.2001 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0047 | 0.0401 | 0.0635 |
Trichomonas vaginalis | set domain proteins, putative | 0.0376 | 0.4439 | 1 |
Echinococcus granulosus | GMP synthase glutamine hydrolyzing | 0.0096 | 0.1 | 0.1585 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0301 | 0.3517 | 0.5573 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0089 | 0.0916 | 0.3222 |
Brugia malayi | Cation transporter family protein | 0.0045 | 0.0368 | 0.0368 |
Echinococcus granulosus | peregrin | 0.0051 | 0.044 | 0.0698 |
Echinococcus multilocularis | jumonji domain containing protein | 0.007 | 0.0684 | 0.1084 |
Schistosoma mansoni | protein phosphatase 2C | 0.0045 | 0.0368 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0096 | 0.1 | 0.1585 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Plasmodium vivax | hypothetical protein, conserved | 0.0051 | 0.044 | 0.1521 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0047 | 0.0398 | 0.1334 |
Echinococcus granulosus | carbonic anhydrase II | 0.0178 | 0.2001 | 0.317 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.004 | 0.0316 | 0.05 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0045 | 0.0368 | 0.0583 |
Echinococcus granulosus | intermediate filament protein | 0.0024 | 0.0112 | 0.0177 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0178 | 0.2001 | 0.718 |
Brugia malayi | PHD-finger family protein | 0.0051 | 0.044 | 0.044 |
Brugia malayi | intermediate filament protein | 0.0024 | 0.0112 | 0.0112 |
Mycobacterium ulcerans | NAD synthetase | 0.0241 | 0.2774 | 1 |
Echinococcus granulosus | lamin | 0.0024 | 0.0112 | 0.0177 |
Leishmania major | carbonic anhydrase-like protein | 0.0178 | 0.2001 | 0.718 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0038 | 0.0283 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.0916 | 0.0916 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0045 | 0.0368 | 0.0583 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0045 | 0.0368 | 0.0583 |
Onchocerca volvulus | 0.0089 | 0.0916 | 0.0916 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0168 | 0.1879 | 0.2978 |
Plasmodium falciparum | glutamine-dependent NAD(+) synthetase, putative | 0.0241 | 0.2774 | 1 |
Onchocerca volvulus | 0.0089 | 0.0916 | 0.0916 | |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0949 |
Onchocerca volvulus | Alhambra homolog | 0.0051 | 0.044 | 0.044 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0429 | 0.5095 | 0.8073 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.033 | 0.033 |
Schistosoma mansoni | lamin | 0.0024 | 0.0112 | 0.0177 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0429 | 0.5095 | 0.8073 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0038 | 0.0283 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1 | 0.1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0094 | 0.0094 |
Mycobacterium ulcerans | GMP synthase | 0.0096 | 0.1 | 0.353 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0961 | 0.0961 |
Echinococcus granulosus | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Schistosoma mansoni | lamin | 0.0024 | 0.0112 | 0.0177 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0018 | 0.0043 | 0.0069 |
Trypanosoma brucei | GMP synthase [glutamine-hydrolysing] | 0.0096 | 0.1 | 0.3555 |
Toxoplasma gondii | hypothetical protein | 0.0096 | 0.1 | 0.3556 |
Treponema pallidum | NAD synthetase | 0.0241 | 0.2774 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0047 | 0.0401 | 0.0635 |
Toxoplasma gondii | exonuclease III APE | 0.0017 | 0.0033 | 0.0039 |
Onchocerca volvulus | 0.0089 | 0.0916 | 0.0916 | |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0045 | 0.0368 | 0.0583 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.0094 | 0.0223 |
Onchocerca volvulus | 0.0024 | 0.0112 | 0.0112 | |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0051 | 0.044 | 0.1521 |
Onchocerca volvulus | 0.0024 | 0.0112 | 0.0112 | |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0178 | 0.2001 | 0.7191 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0528 | 0.6311 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0368 | 0.0368 |
Echinococcus multilocularis | peregrin | 0.0051 | 0.044 | 0.0698 |
Leishmania major | GMP synthase, putative,glutamine amidotransferase, putative | 0.0096 | 0.1 | 0.353 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0024 | 0.0112 | 0.0112 |
Schistosoma mansoni | gliotactin | 0.0089 | 0.0916 | 0.1451 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0045 | 0.0368 | 0.0583 |
Schistosoma mansoni | jumonji domain containing protein | 0.0238 | 0.2744 | 0.4349 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0112 | 0.0112 |
Schistosoma mansoni | acetylcholinesterase | 0.0089 | 0.0916 | 0.1451 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0368 | 0.0368 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0096 | 0.1 | 0.1585 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Mycobacterium tuberculosis | Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) | 0.0241 | 0.2774 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0017 | 0.0033 | 0.0052 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0089 | 0.0916 | 0.2004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.004 | 0.0316 | 0.05 |
Onchocerca volvulus | 0.0089 | 0.0916 | 0.0916 | |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0272 | 0.3163 | 0.5012 |
Schistosoma mansoni | ap endonuclease | 0.0017 | 0.0033 | 0.0052 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0047 | 0.0398 | 0.0631 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0017 | 0.0033 | 0.0039 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.0094 | 0.0223 |
Loa Loa (eye worm) | carboxylesterase | 0.0089 | 0.0916 | 0.0916 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0051 | 0.044 | 0.044 |
Plasmodium falciparum | carbonic anhydrase | 0.0096 | 0.1 | 0.3556 |
Echinococcus granulosus | geminin | 0.0164 | 0.1828 | 0.2897 |
Echinococcus multilocularis | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Echinococcus granulosus | lamin dm0 | 0.0024 | 0.0112 | 0.0177 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0047 | 0.0398 | 0.1368 |
Loa Loa (eye worm) | hypothetical protein | 0.0829 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0916 | 0.0916 |
Trichomonas vaginalis | nh(3)-dependent NAD(+) synthetase, putative | 0.0241 | 0.2774 | 0.6221 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0045 | 0.0368 | 0.1258 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.044 | 0.0698 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0.0398 | 0.083 |
Brugia malayi | hypothetical protein | 0.0104 | 0.11 | 0.11 |
Brugia malayi | PHD-finger family protein | 0.0017 | 0.0022 | 0.0022 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0051 | 0.044 | 0.0698 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0096 | 0.1 | 0.1 |
Trypanosoma cruzi | NAD+ synthase, putative | 0.0241 | 0.2774 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0448 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0096 | 0.1 | 0.1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0045 | 0.0368 | 0.0584 |
Trypanosoma brucei | NAD+ synthase, putative | 0.0241 | 0.2774 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.4059 | 0.4059 |
Schistosoma mansoni | intermediate filament proteins | 0.0024 | 0.0112 | 0.0177 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0045 | 0.0368 | 0.0583 |
Brugia malayi | jmjC domain containing protein | 0.0272 | 0.3163 | 0.3163 |
Loa Loa (eye worm) | carboxylesterase | 0.0089 | 0.0916 | 0.0916 |
Brugia malayi | Bromodomain containing protein | 0.0051 | 0.044 | 0.044 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.033 | 0.3878 | 0.3878 |
Onchocerca volvulus | 0.0045 | 0.0368 | 0.0368 | |
Echinococcus multilocularis | geminin | 0.0164 | 0.1828 | 0.2897 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.004 | 0.0316 | 0.05 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0096 | 0.1 | 0.1 |
Onchocerca volvulus | 0.0089 | 0.0916 | 0.0916 | |
Schistosoma mansoni | carbonic anhydrase-related | 0.0096 | 0.1 | 0.1585 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0047 | 0.0401 | 0.0635 |
Onchocerca volvulus | 0.0376 | 0.4439 | 0.4439 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0089 | 0.0916 | 0.1451 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0047 | 0.0398 | 0.1334 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0045 | 0.0368 | 0.0368 |
Onchocerca volvulus | Huntingtin homolog | 0.0104 | 0.11 | 0.11 |
Toxoplasma gondii | bifunctional GMP synthase/glutamine amidotransferase protein | 0.0096 | 0.1 | 0.3555 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0047 | 0.0398 | 0.1334 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0047 | 0.0398 | 0.0631 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0528 | 0.6311 | 0.6311 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.004 | 0.0316 | 0.05 |
Echinococcus granulosus | acetylcholinesterase | 0.0528 | 0.6311 | 1 |
Schistosoma mansoni | GMP synthetase | 0.0096 | 0.1 | 0.1585 |
Schistosoma mansoni | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.004 | 0.0316 | 0.05 |
Echinococcus multilocularis | acetylcholinesterase | 0.0528 | 0.6311 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0089 | 0.0916 | 0.1451 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0038 | 0.0283 | 0.0913 |
Schistosoma mansoni | ap endonuclease | 0.0017 | 0.0033 | 0.0052 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0047 | 0.0398 | 0.1334 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0096 | 0.1 | 0.1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0104 | 0.1102 | 0.1102 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.004 | 0.0316 | 0.0316 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0368 | 0.0368 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0178 | 0.2001 | 0.317 |
Schistosoma mansoni | glutamine-dependent NAD(+) synthetase | 0.0144 | 0.1592 | 0.2523 |
Echinococcus multilocularis | GMP synthase (glutamine hydrolyzing) | 0.0096 | 0.1 | 0.1585 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0272 | 0.3163 | 0.5012 |
Echinococcus multilocularis | muscleblind protein | 0.0093 | 0.0961 | 0.1522 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0045 | 0.0368 | 0.0583 |
Plasmodium vivax | glutamine-dependent NAD(+) synthetase, putative | 0.0241 | 0.2774 | 1 |
Brugia malayi | AF-10 protein | 0.0017 | 0.0022 | 0.0022 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0047 | 0.0398 | 0.0631 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0168 | 0.1879 | 0.1879 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.0094 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0022 | 0.0022 |
Echinococcus multilocularis | phd:f box containing protein | 0.0045 | 0.0368 | 0.0583 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0045 | 0.0368 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0368 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0528 | 0.6311 | 0.6311 |
Onchocerca volvulus | Huntingtin homolog | 0.0104 | 0.11 | 0.11 |
Giardia lamblia | PHD finger protein 15 | 0.0051 | 0.044 | 0.1488 |
Trypanosoma cruzi | NAD+ synthase, putative | 0.0241 | 0.2774 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.007 | 0.0684 | 0.1084 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0022 | 0.0094 | 0.0149 |
Plasmodium vivax | JmjC domain containing protein | 0.0045 | 0.0368 | 0.1258 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0017 | 0.0033 | 0.0039 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0178 | 0.2001 | 0.317 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0089 | 0.0916 | 0.1451 |
Toxoplasma gondii | glutamine-dependent NAD(+) synthetase protein, putative | 0.0241 | 0.2774 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0528 | 0.6311 | 1 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0045 | 0.0368 | 0.0583 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0022 | 0.0094 | 0.0149 |
Echinococcus granulosus | acetylcholinesterase | 0.0528 | 0.6311 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0528 | 0.6311 | 0.6311 |
Echinococcus multilocularis | lamin dm0 | 0.0024 | 0.0112 | 0.0177 |
Echinococcus granulosus | neuroligin | 0.0089 | 0.0916 | 0.1451 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.1828 | 0.2897 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0429 | 0.5095 | 0.8073 |
Echinococcus granulosus | phd:f box containing protein | 0.0045 | 0.0368 | 0.0583 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1 | 0.1585 |
Brugia malayi | Carboxylesterase family protein | 0.0528 | 0.6311 | 0.6311 |
Echinococcus granulosus | carbonic anhydrase | 0.0096 | 0.1 | 0.1585 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0301 | 0.3517 | 0.5573 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0528 | 0.6311 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | 0 uM | Anti-proliferative activity of the compound was evaluated by its ability to inhibit proliferation of SW480 cells; na means Not active | ChEMBL. | 11844707 |
IC50 (binding) | >= 100 uM | Displacement of [3H]-9-cis-RA from human GST-tagged N-terminal truncated RXRalpha after 1 hr by liquid scintillation counting | ChEMBL. | 23434637 |
IC50 (functional) | = 310 uM | Anti-proliferative activity of the compound was evaluated by its ability to inhibit proliferation of MDCK-f3 (Madin-Darby canine kidney f3) cell line | ChEMBL. | 11844707 |
IC50 (functional) | = 460 uM | Anti-proliferative activity of the compound was evaluated by its ability to inhibit proliferation of MDCK cells | ChEMBL. | 11844707 |
IC50 (functional) | = 480 uM | Anti-proliferative activity of the compound was evaluated by its ability to inhibit proliferation of murine NIH3T3 fibroblasts | ChEMBL. | 11844707 |
IC50 (functional) | = 480 uM | Anti-proliferative activity of the compound was evaluated by its ability to inhibit proliferation of murine NIH3T3 fibroblasts | ChEMBL. | 11844707 |
IC50 (functional) | = 500 uM | Anti-proliferative activity of the compound was evaluated by its ability to inhibit proliferation of rat embryonic fibroblasts (REF) | ChEMBL. | 11844707 |
Inhibitory activity (functional) | = 1.6 | Half-maximal inhibition of the COX activity was measured by the direct analysis of the consumed O2 using isolated sheep seminal vesicles | ChEMBL. | 11844707 |
Inhibitory activity (functional) | = 1.6 | Half-maximal inhibition of the COX activity was measured by the direct analysis of the consumed O2 using isolated sheep seminal vesicles | ChEMBL. | 11844707 |
Inhibitory activity (binding) | = 10 | Inhibition of p21ras protein and Raf kinase in vitro using recombinant proteins | ChEMBL. | 11844707 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.