Detailed information for compound 278124

Basic information

Technical information
  • TDR Targets ID: 278124
  • Name: 3-(pyrazol-1-ylmethyl)benzonitrile
  • MW: 183.209 | Formula: C11H9N3
  • H donors: 0 H acceptors: 2 LogP: 1.55 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1cccc(c1)Cn1cccn1
  • InChi: 1S/C11H9N3/c12-8-10-3-1-4-11(7-10)9-14-6-2-5-13-14/h1-7H,9H2
  • InChiKey: XBYBAGJXNBFJON-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(1-pyrazolylmethyl)benzonitrile
  • 3-(pyrazol-1-ylmethyl)benzenecarbonitrile

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus biogenic amine 5HT receptor 0.0135 0.0494 0.0899
Loa Loa (eye worm) carboxylesterase 0.0537 0.2144 0.5701
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0021 0.0007
Brugia malayi Protein kinase domain containing protein 0.0032 0.0071 0.018
Schistosoma mansoni biogenic amine receptor 0.0135 0.0494 0.089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0494 0.089
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.0494 0.0899
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0066 0.0175
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0018 0.0011
Plasmodium falciparum glutathione reductase 0.0929 0.3756 1
Trypanosoma cruzi hypothetical protein, conserved 0.0189 0.0716 0.0709
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0189 0.0716 0.1853
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0156 0.0272
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0021 0.0014
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0712 0.2864 0.2859
Mycobacterium ulcerans oxidoreductase 0.002 0.0021 0.001
Onchocerca volvulus 0.0173 0.0653 0.1992
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0062 0.0193 0.0351
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Brugia malayi hypothetical protein 0.0058 0.0177 0.0463
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0047 0.0083
Echinococcus multilocularis Polycystic kidney disease protein 0.0121 0.0438 0.0798
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0108 0.0307
Brugia malayi Thioredoxin reductase 0.0929 0.3756 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0189 0.0716 0.1891
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0173
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.0349 0.0634
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0072 0.0234 0.0573
Brugia malayi hypothetical protein 0.0462 0.1838 0.4888
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0061 0.0098
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0018 0.003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0936 0.3785 1
Loa Loa (eye worm) thioredoxin reductase 0.0929 0.3756 1
Schistosoma mansoni chromobox protein 0.0073 0.0239 0.0424
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0192 0.0338
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0189 0.0716 0.1305
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0011 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Loa Loa (eye worm) hypothetical protein 0.0275 0.1068 0.2831
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0135 0.0494 0.1307
Brugia malayi Dopamine receptor protein 2 0.0135 0.0494 0.1307
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.02 0.0641
Loa Loa (eye worm) hypothetical protein 0.0537 0.2144 0.5701
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0066 0.0167
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0021 0.0007
Mycobacterium tuberculosis Carboxylesterase LipT 0.0091 0.0312 0.0781
Echinococcus granulosus carbonyl reductase 1 0.002 0.0021 0.0035
Onchocerca volvulus 0.0135 0.0494 0.1492
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.0349 0.0342
Brugia malayi Cytochrome P450 family protein 0.0019 0.0018 0.0038
Brugia malayi ORL1-like opioid receptor 0.0135 0.0494 0.1307
Echinococcus multilocularis neuropeptide s receptor 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.0023 0.0032 0.0067
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0018 0.0011
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0021 0.0037
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0021 0.0037
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0152 0.0264
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Brugia malayi Dopamine receptor 0.0135 0.0494 0.1307
Mycobacterium ulcerans dehydrogenase 0.002 0.0021 0.001
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0061 0.0108
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0239 0.0717
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0189 0.0716 0.1891
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Brugia malayi Carboxylesterase family protein 0.0537 0.2144 0.5705
Toxoplasma gondii oxidoreductase, putative 0.002 0.0021 0.0037
Leishmania major short chain dehydrogenase, putative 0.002 0.0021 0.0014
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0135 0.0494 0.1307
Brugia malayi Uncoordinated protein 44 0.0031 0.0068 0.017
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0173
Echinococcus granulosus peptide allatostatin:somatostatin 0.0135 0.0494 0.0899
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0695 0.2797 0.7442
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.0494 0.089
Echinococcus granulosus para nitrobenzyl esterase 0.0091 0.0312 0.0567
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0021 0.0007
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0018 0.0011
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0135 0.0494 0.089
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0062 0.0193 0.0187
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0406 0.1244
Schistosoma mansoni adenoreceptor 0.0135 0.0494 0.089
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0712 0.2864 1
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0021 0.0025
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0083 0.0076
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0712 0.2864 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus multilocularis transfer RNA-Lys 0.0074 0.0245 0.0444
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0021 0.0035
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Schistosoma mansoni intermediate filament proteins 0.0058 0.018 0.0316
Echinococcus multilocularis fmrfamide receptor 0.0135 0.0494 0.0899
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0152
Brugia malayi Heterochromatin protein 1 0.0073 0.0239 0.0627
Leishmania major short chain dehydrogenase, putative 0.002 0.0021 0.0014
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0004
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0152 0.1911
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0011 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1086 0.44 0.8032
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0021 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0066 0.0175
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0135 0.0494 0.0899
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0135 0.0494 0.089
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.0494 0.0899
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0047 0.0113
Schistosoma mansoni myosin xvIII 0.0135 0.0494 0.089
Echinococcus multilocularis 0.0019 0.0018 0.003
Echinococcus granulosus thioredoxin glutathione reductase 0.0929 0.3756 0.6855
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Onchocerca volvulus 0.0091 0.0312 0.0919
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0021 0.0045
Trypanosoma brucei C-8 sterol isomerase, putative 0.0423 0.1677 0.1671
Schistosoma mansoni single-minded 0.01 0.0352 0.063
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0021 0.0007
Onchocerca volvulus 0.0135 0.0494 0.1492
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0047 0.0113
Echinococcus multilocularis lamin dm0 0.0058 0.018 0.0325
Brugia malayi hypothetical protein 0.0121 0.0438 0.1158
Brugia malayi Melatonin receptor type 1A 0.0135 0.0494 0.1307
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0189 0.0716 0.2217
Schistosoma mansoni disulfide oxidoreductase 0.0189 0.0716 0.1296
Echinococcus granulosus neuroligin 0.0091 0.0312 0.0567
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0061 0.0098
Echinococcus granulosus inositol monophosphatase 1 0.008 0.0268 0.0487
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0061 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Onchocerca volvulus 0.0135 0.0494 0.1492
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0712 0.2864 0.7555
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0712 0.2864 0.5227
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Trichomonas vaginalis glutamate synthase, putative 0.0189 0.0716 0.2217
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0189 0.0716 0.2452
Onchocerca volvulus 0.0135 0.0494 0.1492
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0406 0.1364
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0018 0.0031
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0091 0.0312 0.0781
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0068 0.0148
Loa Loa (eye worm) hypoxia-induced factor 1 0.0311 0.1216 0.3224
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0026 0.0046 0.0082
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0021 0.001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0494 0.0899
Leishmania major cytochrome p450-like protein 0.0019 0.0018 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0173
Brugia malayi Retinol dehydrogenase 12 0.002 0.0021 0.0045
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0406 0.5562
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0936 0.3785 1
Echinococcus granulosus death domain containing protein 0.0031 0.0068 0.0121
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0026 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.0162
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0239 0.0717
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0189 0.0716 0.1891
Onchocerca volvulus 0.0058 0.018 0.0501
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0018 0.0011
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0189 0.0716 0.1853
Echinococcus granulosus lipoxygenase domain containing protein 0.0121 0.0438 0.0798
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0021 0.0035
Schistosoma mansoni amine GPCR 0.0135 0.0494 0.089
Brugia malayi bHLH-PAS transcription factor 0.0074 0.0245 0.0643
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0018 0.0029
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0135 0.0494 0.0899
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0712 0.2864 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0268 0.0261
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0464 0.1846 0.3369
Echinococcus granulosus hypothetical protein 0.0927 0.3749 0.6843
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0047 0.0113
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1811 0.738 0.7378
Plasmodium falciparum ferrodoxin reductase-like protein 0.0189 0.0716 0.1891
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0135 0.0494 0.0899
Schistosoma mansoni hypothetical protein 0.0135 0.0494 0.089
Onchocerca volvulus 0.0135 0.0494 0.1492
Schistosoma mansoni lamin 0.0058 0.018 0.0316
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0413 0.1637 0.4298
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0018 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.0929 0.3756 0.3751
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0083 0.0076
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0051 0.0044
Echinococcus granulosus intermediate filament protein 0.0058 0.018 0.0325
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0152
Echinococcus multilocularis somatostatin receptor 0.0135 0.0494 0.0899
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0135 0.0494 0.1307
Giardia lamblia NADH oxidase lateral transfer candidate 0.0712 0.2864 1
Brugia malayi hypoxia-induced factor 1 0.0311 0.1216 0.323
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0021 0.001
Onchocerca volvulus 0.0029 0.0061 0.0126
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0712 0.2864 0.7622
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0205 0.0371
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0189 0.0716 0.1891
Onchocerca volvulus 0.0792 0.3192 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0187 0.0709 0.1282
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0189 0.0716 0.1305
Brugia malayi MAP kinase sur-1 0.01 0.0349 0.0919
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0021 0.0014
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.0012 0.0009
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0018 0.0011
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0712 0.2864 0.2859
Echinococcus granulosus g protein coupled receptor 0.0135 0.0494 0.0899
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0018 0.0001
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0068 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Leishmania major hypothetical protein, conserved 0.002 0.0021 0.0014
Echinococcus granulosus carboxylesterase 5A 0.0537 0.2144 0.3913
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0406 0.1031
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0097 0.0241
Brugia malayi hypothetical protein 0.0121 0.0438 0.1158
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0009
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0189 0.0716 0.1305
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0018 0.0011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0029 0.005
Brugia malayi chromobox protein homolog 3 0.0041 0.0107 0.0276
Schistosoma mansoni rab6-interacting 0.0121 0.0438 0.0788
Loa Loa (eye worm) hypothetical protein 0.0337 0.1323 0.351
Schistosoma mansoni neuropeptide receptor 0.0135 0.0494 0.089
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.008 0.0268 0.0878
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0068 0.0121
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0712 0.2864 0.7622
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0021 0.0014
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0091 0.0312 0.0567
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0152 0.0274
Echinococcus granulosus carbonyl reductase 1 0.002 0.0021 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Onchocerca volvulus Glucosylceramidase homolog 0.0195 0.0739 0.2264
Echinococcus multilocularis RUN 0.0121 0.0438 0.0798
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0021 0.0007
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0083 0.0149
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0021 0.0035
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0135 0.0494 0.1299
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Leishmania major protein kinase, putative 0.0032 0.0071 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0021 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0494 0.0899
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0143
Trypanosoma brucei protein kinase, putative 0.01 0.0349 0.0342
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Plasmodium falciparum glutathione reductase 0.0712 0.2864 0.7622
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0143
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0152 0.0145
Echinococcus granulosus G protein coupled receptor 139 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.0041 0.0107 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0782 0.2425
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0187 0.0709 0.2426
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0068 0.0121
Brugia malayi Death domain containing protein 0.0031 0.0068 0.017
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0021 0.0035
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0091 0.0312 0.0948
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0007 0.001
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0189 0.0716 0.1305
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0413 0.1637 0.4298
Plasmodium falciparum LCCL domain-containing protein 0.0121 0.0438 0.115
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0712 0.2864 0.2859
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0312 0.0558
Schistosoma mansoni inositol monophosphatase 0.008 0.0268 0.0478
Echinococcus multilocularis sex peptide receptor 0.0135 0.0494 0.0899
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0152 0.0145
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0192 0.0348
Mycobacterium tuberculosis Probable dehydrogenase 0.0413 0.1637 0.4298
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Brugia malayi putative neuropeptide receptor 0.0135 0.0494 0.1307
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0066 0.0167
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0021 0.0031
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.026 0.101 0.1841
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0012 0.0009
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0047 0.0113
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0021 0.0014
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0268 0.0261
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.0349 0.0911
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.02 0.0641
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium ulcerans oxidoreductase 0.002 0.0021 0.001
Echinococcus multilocularis G protein coupled receptor 139 0.0135 0.0494 0.0899
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0021 0.0025
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0011 0.0004
Echinococcus granulosus Ankyrin 0.0031 0.0069 0.0123
Echinococcus multilocularis inositol monophosphatase 1 0.008 0.0268 0.0487
Brugia malayi Carboxylesterase family protein 0.0091 0.0312 0.0822
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0189 0.0716 0.2452
Schistosoma mansoni neuroligin 3 (S09 family) 0.0091 0.0312 0.0558
Brugia malayi 6-phosphofructokinase 0.0114 0.0407 0.1074
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0007 0.001
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0062 0.0193 0.0351
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0312 0.0558
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0712 0.2864 0.7624
Echinococcus multilocularis jun protein 0.026 0.101 0.1841
Leishmania major hypothetical protein, conserved 0.0058 0.0177 0.0171
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Schistosoma mansoni BC026374 protein (S09 family) 0.0091 0.0312 0.0558
Treponema pallidum thioredoxin reductase (trxB) 0.0189 0.0716 0.2451
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0018 0.0029
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0083 0.0076
Echinococcus granulosus lamin dm0 0.0058 0.018 0.0325
Brugia malayi Doublecortin family protein 0.0121 0.0438 0.1158
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0018 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.02 0.0641
Loa Loa (eye worm) hypothetical protein 0.0462 0.1838 0.4883
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0108 0.0307
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0047 0.0106
Brugia malayi RNA binding protein 0.0064 0.0205 0.0535
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0712 0.2864 0.7626
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0018 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0021 0.0007
Echinococcus granulosus RUN 0.0121 0.0438 0.0798
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0065 0.0171
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0189 0.0716 0.2217
Echinococcus multilocularis neuropeptide receptor 0.0135 0.0494 0.0899
Brugia malayi hypothetical protein 0.0091 0.0312 0.0822
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0712 0.2864 0.2859
Mycobacterium tuberculosis Probable oxidoreductase 0.0936 0.3785 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0712 0.2864 0.5222
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0021 0.0035
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0189 0.0716 0.0709
Plasmodium vivax ataxin-2 like protein, putative 0.0058 0.0177 0.0473
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0018 0.0029
Echinococcus multilocularis sodium channel protein 0.0135 0.0494 0.09
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0021 0.0035
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0047 0.004
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0712 0.2864 1
Echinococcus multilocularis glutamate synthase 0.0189 0.0716 0.1305
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0152 0.0145
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0205 0.0527
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0406 0.1364
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0018 0.0011
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0021 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0349 0.1062
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0061 0.0108
Loa Loa (eye worm) norepinephrine transporter 0.0173 0.0653 0.1722
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0349 0.0636
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0189 0.0716 0.1853
Loa Loa (eye worm) TYRA-2 protein 0.0135 0.0494 0.1299
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0135 0.0494 0.1492
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0523 0.2088 0.5555
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0205 0.0361
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Brugia malayi G protein-coupled receptor F59B2.13 0.0135 0.0494 0.1307
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0268 0.081
Leishmania major hypothetical protein, conserved 0.0189 0.0716 0.0709
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.004 0.0033
Echinococcus granulosus hypothetical protein 0.002 0.0021 0.0035
Leishmania major cytochrome p450-like protein 0.0019 0.0018 0.0011
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Echinococcus granulosus transcription factor Dp 1 0.0036 0.0087 0.0156
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0021 0.0014
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0021 0.0009
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0121 0.0438 0.115
Echinococcus multilocularis geminin 0.0172 0.0648 0.1181
Echinococcus multilocularis BC026374 protein (S09 family) 0.0091 0.0312 0.0567
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0187 0.0709 0.0702
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0068 0.0163
Brugia malayi hypothetical protein 0.002 0.0021 0.0045
Echinococcus granulosus neuropeptide receptor 0.0135 0.0494 0.0899
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0021 0.0045
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0189 0.0716 0.2451
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0083 0.0203
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0037
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0029 0.0061 0.0108
Brugia malayi PAS domain containing protein 0.01 0.0352 0.0928
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.0494 0.0899
Schistosoma mansoni netrin receptor unc5 0.0031 0.0068 0.0111
Schistosoma mansoni carbonyl reductase 0.002 0.0021 0.0025
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0406 0.1065
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2066 0.843 0.8429
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.0494 0.0899
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0118
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0189 0.0716 0.1898
Giardia lamblia Thioredoxin reductase 0.0189 0.0716 0.2451
Schistosoma mansoni hypothetical protein 0.0135 0.0494 0.089
Echinococcus granulosus glutamate synthase 0.0189 0.0716 0.1305
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0537 0.2144 0.3906
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0021 0.0037
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0268 0.081
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.02 0.0353
Loa Loa (eye worm) hypothetical protein 0.0058 0.0177 0.0455
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0189 0.0716 0.1305
Echinococcus multilocularis lipoxygenase domain containing protein 0.0121 0.0438 0.0798
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0187 0.0709 0.1833
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0021 0.0014
Brugia malayi Carboxylesterase family protein 0.0091 0.0312 0.0822
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0106
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0189 0.0716 0.0709
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0205 0.0361
Brugia malayi hypothetical protein 0.0029 0.0061 0.0152
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0349 0.0626
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0018 0.0023
Schistosoma mansoni amine GPCR 0.0135 0.0494 0.089
Schistosoma mansoni neuropeptide receptor 0.0135 0.0494 0.089
Echinococcus granulosus serotonin receptor 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0082 0.0224
Echinococcus multilocularis orexin receptor type 2 0.0135 0.0494 0.0899
Echinococcus multilocularis chromobox protein 1 0.0073 0.0239 0.0433
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0413 0.1637 0.4298
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0021 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0021 0.0035
Giardia lamblia Reductase, putative 0.002 0.0021 0.0009
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0142 0.0368
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0135 0.0494 0.1307
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0047 0.0113
Schistosoma mansoni microtubule-associated protein tau 0.1348 0.5478 1
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0187 0.0709 0.1291
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0423 0.1677 0.1671
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.0494 0.0899
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0349 0.0626
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0143
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0189 0.0716 0.1853
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0135 0.0494 0.0899
Echinococcus multilocularis microtubule associated protein 2 0.1348 0.5478 1
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0068 0.0121
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Brugia malayi RE15519p 0.0135 0.0494 0.1307
Loa Loa (eye worm) glutathione reductase 0.0929 0.3756 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.009 0.0162
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Echinococcus granulosus bloom syndrome protein 0.0022 0.0029 0.005
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0021 0.0007
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0021 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0173
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Schistosoma mansoni glutamate synthase 0.0189 0.0716 0.1296
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1811 0.738 0.7378
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0021 0.0014
Echinococcus granulosus g-protein coupled receptor 0.0135 0.0494 0.0899
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0061 0.0108
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.0494 0.0899
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0406 0.1244
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.009 0.0162
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0167 0.0627 0.1655
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0107 0.0304
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0187 0.0709 0.2426
Brugia malayi hypothetical protein 0.0205 0.078 0.2069
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni aryl hydrocarbon receptor 0.01 0.0352 0.063
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus multilocularis dro:myosuppressin receptor 0.0135 0.0494 0.0899
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0021 0.0014
Trichomonas vaginalis glutamate synthase, putative 0.0189 0.0716 0.2217
Schistosoma mansoni alpha-1 adrenergic receptor 0.0135 0.0494 0.089
Loa Loa (eye worm) dehydrogenase 0.002 0.0021 0.0037
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0047 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Echinococcus multilocularis neuropeptide receptor 0.0135 0.0494 0.0899
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0349 0.1062
Echinococcus multilocularis G-protein coupled receptor, putative 0.0135 0.0494 0.0899
Toxoplasma gondii oxidoreductase, putative 0.002 0.0021 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0205 0.0361
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0152 0.0386
Onchocerca volvulus 0.0058 0.018 0.0501
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0061 0.0098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2066 0.843 0.8429
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0083 0.0221
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0018 0.0011
Leishmania major hypothetical protein, conserved 0.0189 0.0716 0.0709
Schistosoma mansoni hypothetical protein 0.0172 0.0648 0.1172
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.002 0.0021 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.0494 0.0899
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Onchocerca volvulus 0.0205 0.078 0.2394
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0021 0.0014
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0021 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0268 0.0261
Brugia malayi Cytochrome P450 family protein 0.0019 0.0018 0.0038
Echinococcus granulosus phd:f box containing protein 0.0016 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0069 0.0165
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0011 0.001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0275 0.1068 0.194
Loa Loa (eye worm) carboxylesterase 0.0091 0.0312 0.0814
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0189 0.0716 0.1853
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0018 0.003
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0018 0.002
Brugia malayi G-protein coupled receptor 0.0135 0.0494 0.1307
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0406 0.073
Echinococcus granulosus chromobox protein 1 0.0073 0.0239 0.0433
Echinococcus multilocularis lamin 0.0058 0.018 0.0325
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0037
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0929 0.3756 0.9921
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0062 0.0193 0.0497
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0066 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0069 0.0113
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0021 0.0045
Echinococcus granulosus tar DNA binding protein 0.0064 0.0205 0.0371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0011 0.0017
Echinococcus granulosus lipoxygenase domain containing protein 0.0121 0.0438 0.0798
Echinococcus multilocularis musashi 0.0058 0.018 0.0325
Brugia malayi larval opioid receptor 0.0135 0.0494 0.1307
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0083 0.0149
Schistosoma mansoni neuropeptide receptor 0.0135 0.0494 0.089
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.0494 0.0899
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0021 0.001
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0062 0.0193 0.2511
Loa Loa (eye worm) doublecortin family protein 0.0121 0.0438 0.115
Plasmodium vivax amine transporter, putative 0.0029 0.0061 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0406 0.1244
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0189 0.0716 0.1853
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0239 0.0618
Echinococcus granulosus jun protein 0.026 0.101 0.1841
Loa Loa (eye worm) RNA binding protein 0.0064 0.0205 0.0527
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0312 0.0558
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0018 0.0011
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0018 0.003
Echinococcus granulosus sex peptide receptor 0.0135 0.0494 0.0899
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0192 0.0494
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0018 0.003
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0349 0.0342
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0189 0.0716 0.2452
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0021 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0112 0.0398 0.0715
Trichomonas vaginalis inositol monophosphatase, putative 0.008 0.0268 0.081
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0021 0.001
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0143
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0327 0.0861
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0029 0.0057
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.1029
Onchocerca volvulus 0.0135 0.0494 0.1492
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0406 0.1031
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0029 0.0061 0.0049
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0189 0.0716 0.2217
Echinococcus granulosus steroid dehydrogenase 0.002 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0061 0.0098
Mycobacterium ulcerans NADH dehydrogenase 0.0189 0.0716 0.2452
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0032 0.0076
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0021 0.001
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Schistosoma mansoni hypothetical protein 0.0135 0.0494 0.089
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0189 0.0716 0.1305
Onchocerca volvulus 0.0135 0.0494 0.1492
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0205 0.0361
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0018 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.1086 0.44 0.8032
Loa Loa (eye worm) intermediate filament protein 0.0058 0.018 0.046
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.1158 0.3607
Schistosoma mansoni amine GPCR 0.0135 0.0494 0.089
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0021 0.0035
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0021 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Echinococcus granulosus lamin 0.0058 0.018 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0047 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0068 0.017
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.0494 0.089
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0007 0.001
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0142 0.0359
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.0349 0.0342
Treponema pallidum sodium- and chloride- dependent transporter 0.0173 0.0653 0.2228
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0152
Brugia malayi Serotonin receptor 0.0135 0.0494 0.1307
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0189 0.0716 0.1853
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0189 0.0716 0.1906
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.1029
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Echinococcus multilocularis chromobox protein 1 0.0073 0.0239 0.0433
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0018 0.0011
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0187 0.0709 0.1879
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0177 0.0171
Onchocerca volvulus 0.0135 0.0494 0.1492
Onchocerca volvulus 0.0135 0.0494 0.1492
Brugia malayi Carboxylesterase family protein 0.0091 0.0312 0.0822
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0159 0.0595 0.1084
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0413 0.1637 0.4298
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0107 0.0273
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0018 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2449 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0047 0.0113
Onchocerca volvulus 0.0091 0.0312 0.0919
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0004
Echinococcus multilocularis Ankyrin 0.0031 0.0069 0.0123
Onchocerca volvulus 0.0112 0.0398 0.1191
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0205 0.0527
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0021 0.0035
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0021 0.0037
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0021 0.0007
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Onchocerca volvulus 0.0135 0.0494 0.1492
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.001 0.0006
Echinococcus multilocularis serotonin receptor 0.0275 0.1068 0.1948
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0018 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0275 0.1068 0.1948
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Loa Loa (eye worm) cytochrome P450 0.0019 0.0018 0.0029
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0009
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0066 0.0157
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.026 0.101 0.1841
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0189 0.0716 0.1305
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0107 0.0304
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0021 0.0035
Brugia malayi hypothetical protein 0.002 0.0021 0.0045
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0032 0.0056
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0021 0.0035
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0029 0.0057
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.0494 0.0899
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0018 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Schistosoma mansoni biogenic amine receptor 0.0135 0.0494 0.089
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0494 0.0899
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Plasmodium vivax SET domain protein, putative 0.01 0.0349 0.093
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0189 0.0716 0.2217
Onchocerca volvulus Neuropeptide F receptor homolog 0.0135 0.0494 0.1492
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.02 0.0363
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0018 0.0029
Brugia malayi AKH receptor 0.0135 0.0494 0.1307
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0051 0.0044
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.002
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0189 0.0716 0.2452
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.012 0.0313
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0032 0.0046
Echinococcus granulosus serotonin transporter 0.0173 0.0653 0.1189
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0189 0.0716 0.0709
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0021 0.001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0047 0.0113
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0142 0.0256
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0007 0.001
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0018 0.0024
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0189 0.0716 0.0709
Leishmania major dehydrogenase-like protein 0.002 0.0021 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2449 1 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0021 0.001
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0135 0.0494 0.0899
Mycobacterium ulcerans dehydrogenase 0.0189 0.0716 0.2452
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0135 0.0494 0.089
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0423 0.1677 0.4459
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0177 0.0455
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Loa Loa (eye worm) hypothetical protein 0.0173 0.0653 0.1722
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0083 0.0203
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0296 0.1158 0.3076
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0349 0.0636
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0189 0.0716 0.1305
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0061 0.0108
Plasmodium vivax glutathione reductase, putative 0.0929 0.3756 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0189 0.0716 0.2217
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0494 0.0899
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0494 0.0899
Trypanosoma brucei hypothetical protein, conserved 0.0189 0.0716 0.0709
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0189 0.0716 0.2452
Loa Loa (eye worm) RecQ helicase 0.0022 0.0029 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.1158 0.3607
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0029 0.0061 0.0108
Schistosoma mansoni survival motor neuron protein 0.0094 0.0327 0.0584
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0173
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0406 0.1065
Plasmodium vivax ferrodoxin reductase, putative 0.0189 0.0716 0.1906
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0007 0.001
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0021 0.0035
Trichomonas vaginalis mercuric reductase, putative 0.0712 0.2864 0.8972
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0037
Trypanosoma cruzi NADH dehydrogenase, putative 0.0189 0.0716 0.0709
Echinococcus multilocularis thioredoxin glutathione reductase 0.0929 0.3756 0.6855
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0187 0.0709 0.1291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Echinococcus granulosus fmrfamide receptor 0.0135 0.0494 0.0899
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0177 0.0171
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0189 0.0716 0.0709
Toxoplasma gondii NADPH-glutathione reductase 0.0712 0.2864 0.7622
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0021 0.0007
Schistosoma mansoni gliotactin 0.0091 0.0312 0.0558
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0189 0.0716 0.2452
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Onchocerca volvulus 0.0189 0.0716 0.2192
Toxoplasma gondii selenide, water dikinase 0.0189 0.0716 0.1891
Trypanosoma brucei NADH dehydrogenase 0.0189 0.0716 0.0709
Trypanosoma cruzi trypanothione reductase, putative 0.0712 0.2864 0.2859
Brugia malayi follicle stimulating hormone receptor 0.0365 0.1439 0.3826
Loa Loa (eye worm) hypothetical protein 0.0423 0.1677 0.4454
Brugia malayi Carboxylesterase family protein 0.0537 0.2144 0.5705
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Echinococcus multilocularis carboxylesterase 5A 0.0537 0.2144 0.3913
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0021 0.0007
Entamoeba histolytica disulphide oxidoreductase, putative 0.0189 0.0716 1
Onchocerca volvulus 0.0091 0.0312 0.0919
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0058 0.015
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0004
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0135 0.0494 0.1299
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0332 0.1302 0.3454
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0108 0.0307
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0021 0.0035
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.02 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0121 0.0346
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0021 0.001
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0018 0.002
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0406 0.073
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0018 0.002
Schistosoma mansoni hypothetical protein 0.0031 0.0068 0.0111
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0108 0.0102
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0189 0.0716 0.1853
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0021 0.0035
Loa Loa (eye worm) dehydrogenase 0.002 0.0021 0.0037
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0152 0.1911
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.0494 0.1299
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0021 0.0035
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0189 0.0716 1
Mycobacterium ulcerans hypothetical protein 0.0189 0.0716 0.2452
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0021 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0349 0.0626
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Onchocerca volvulus 0.0121 0.0438 0.1316
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0021 0.0031
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.02 0.0193
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0135 0.0494 0.089
Brugia malayi G protein-coupled receptor 0.0135 0.0494 0.1307
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0406 0.5562
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0173 0.0653 0.118
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0032 0.0056
Onchocerca volvulus 0.0135 0.0494 0.1492
Loa Loa (eye worm) hypothetical protein 0.061 0.2447 0.6509
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0189 0.0716 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0152 0.0145
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0032 0.0056
Echinococcus multilocularis allatostatin A receptor 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus granulosus dro:myosuppressin receptor 0.0135 0.0494 0.0899
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0108 0.0102
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0047 0.0113
Leishmania major hypothetical protein, conserved 0.0035 0.0083 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0066 0.0175
Brugia malayi putative neuropeptide receptor NPR1 0.0135 0.0494 0.1307
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0189 0.0716 0.0709
Loa Loa (eye worm) hypothetical protein 0.01 0.0349 0.0914
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0021 0.001
Brugia malayi 6-phosphofructokinase 0.0114 0.0406 0.1073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0108 0.0307
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0091 0.0312 0.0567
Onchocerca volvulus 0.0091 0.0312 0.0919
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0135 0.0494 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2449 1 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0018 0.003
Echinococcus granulosus 7TM GPCR rhodopsin 0.0135 0.0494 0.0899
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0018 0.003
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0083 0.0203
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0349 0.1062
Schistosoma mansoni hypothetical protein 0.0059 0.0184 0.0323
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0021 0.0035
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.002 0.0021 0.0007
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0047 0.0083
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0135 0.0494 0.1299
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.0216 0.0827 0.2189
Brugia malayi Serotonin receptor 0.0663 0.2664 0.709
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Plasmodium vivax hypothetical protein, conserved 0.002 0.0021 0.0055
Mycobacterium ulcerans ferredoxin reductase 0.0189 0.0716 0.2452
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0061 0.0143
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0021 0.0035
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0066 0.0157
Giardia lamblia GTOR 0.0052 0.0152 0.0469
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0061 0.0098
Echinococcus multilocularis serotonin receptor 0.0275 0.1068 0.1948
Schistosoma mansoni inositol monophosphatase 0.008 0.0268 0.0478
Echinococcus granulosus hypothetical protein 0.002 0.0021 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.0129
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Schistosoma mansoni carbonyl reductase 0.002 0.0021 0.0025
Treponema pallidum oxidoreductase 0.0189 0.0716 0.2451
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.0349 0.0342
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0142 0.0256
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0032 0.0056
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) hypothetical protein 0.0032 0.0071 0.0171
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0018 0.0029
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0066 0.0157
Leishmania major hypothetical protein, conserved 0.002 0.0021 0.0014
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0066 0.0173
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Echinococcus multilocularis oxidoreductase 0.002 0.0021 0.0035
Mycobacterium leprae Possible regulatory protein 0.0026 0.0047 0.0077
Loa Loa (eye worm) solute carrier family 6 member 4 0.0173 0.0653 0.1722
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Echinococcus multilocularis neuroligin 0.0091 0.0312 0.0567
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0189 0.0716 0.1891
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0018 0.0024
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0021 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0021 0.0014
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0135 0.0494 0.0488
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0173 0.0653 0.1729
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0058 0.015
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Onchocerca volvulus 0.0135 0.0494 0.1492
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Brugia malayi neuropeptide F receptor 0.0135 0.0494 0.1307
Leishmania major protein kinase, putative 0.0027 0.0051 0.0044
Toxoplasma gondii hypothetical protein 0.0029 0.0061 0.0143
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Brugia malayi phosphofructokinase 0.0114 0.0406 0.1073
Schistosoma mansoni histamine h1 receptor 0.0135 0.0494 0.089
Onchocerca volvulus 0.0135 0.0494 0.1492
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0406 0.04
Leishmania major oxidoreductase-like protein 0.002 0.0021 0.0014
Brugia malayi intermediate filament protein 0.0058 0.018 0.0469
Schistosoma mansoni loxhd1 0.0121 0.0438 0.0788
Brugia malayi Cytochrome P450 family protein 0.0019 0.0018 0.0038
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.0494 0.089
Plasmodium falciparum amino acid transporter, putative 0.0029 0.0061 0.0143
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0296 0.1158 0.307
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0349 0.0636
Loa Loa (eye worm) hypothetical protein 0.0173 0.0653 0.1722
Echinococcus granulosus sodium channel protein 0.0135 0.0494 0.09
Onchocerca volvulus 0.0135 0.0494 0.1492
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0135 0.0494 0.0899
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0135 0.0494 0.1299
Entamoeba histolytica thioredoxin reductase, putative 0.0189 0.0716 1
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0205 0.0535
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0712 0.2864 1
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0021 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0007 0.001
Plasmodium falciparum thioredoxin reductase 0.0712 0.2864 0.7622
Trichomonas vaginalis chromobox protein, putative 0.0044 0.012 0.0344
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0118
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Echinococcus granulosus acetylcholinesterase 0.0537 0.2144 0.3913
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0021 0.0031
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0021 0.0014
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0406 0.0739
Onchocerca volvulus 0.0094 0.0327 0.0965
Loa Loa (eye worm) hypothetical protein 0.0044 0.0121 0.0305
Onchocerca volvulus 0.0029 0.0061 0.0126
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0066 0.068
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0018 0.002
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0021 0.001
Echinococcus granulosus Polycystic kidney disease protein 0.0121 0.0438 0.0798
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0135 0.0494 0.089
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Brugia malayi TAR-binding protein 0.0064 0.0205 0.0535
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.0349 0.0634
Echinococcus granulosus neuropeptide FF receptor 2 0.0135 0.0494 0.0899
Brugia malayi Inositol-1 0.008 0.0268 0.0705
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Loa Loa (eye worm) hypothetical protein 0.0057 0.0175 0.0449
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Toxoplasma gondii hypothetical protein 0.0029 0.0061 0.0143
Echinococcus granulosus tachykinin peptides receptor 99D 0.0135 0.0494 0.0899
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Echinococcus multilocularis serotonin transporter 0.0173 0.0653 0.1189
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.02 0.0363
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0152 0.0274
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0021 0.001
Echinococcus granulosus BC026374 protein S09 family 0.0091 0.0312 0.0567
Echinococcus granulosus 7tm_1 domain containing protein 0.0135 0.0494 0.0899
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Schistosoma mansoni opsin-like receptor 0.0135 0.0494 0.089
Brugia malayi glutathione reductase 0.0929 0.3756 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1811 0.738 0.7378
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Plasmodium vivax multidomain scavenger receptor, putative 0.0121 0.0438 0.1167
Schistosoma mansoni polycystin 1-related 0.0121 0.0438 0.0788
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0021 0.0007
Schistosoma mansoni opsin-like receptor 0.0135 0.0494 0.089
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0029 0.0067
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0021 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Echinococcus granulosus chromobox protein 1 0.0073 0.0239 0.0433
Brugia malayi hypothetical protein 0.0337 0.1323 0.3516
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0084 0.0229
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0047 0.0113
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0083 0.0076
Schistosoma mansoni chromobox protein 0.0073 0.0239 0.0424
Loa Loa (eye worm) acetylcholinesterase 1 0.0537 0.2144 0.5701
Schistosoma mansoni lipoxygenase 0.0464 0.1846 0.3362
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Trichomonas vaginalis chromobox protein, putative 0.0044 0.012 0.0344
Echinococcus granulosus g protein coupled receptor 0.0135 0.0494 0.0899
Schistosoma mansoni acetylcholinesterase 0.0091 0.0312 0.0558
Onchocerca volvulus 0.0029 0.0061 0.0126
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0021 0.0014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0712 0.2864 0.5227
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0135 0.0494 0.089
Schistosoma mansoni hypothetical protein 0.0135 0.0494 0.089
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.0494 0.1299
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.1029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Loa Loa (eye worm) hypothetical protein 0.0173 0.0653 0.1722
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0189 0.0716 0.2451
Schistosoma mansoni lamin 0.0058 0.018 0.0316
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0135 0.0494 0.089
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0189 0.0716 0.0709
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0712 0.2864 0.7622
Echinococcus granulosus mitogen activated protein kinase 0.01 0.0349 0.0634
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.02 0.0353
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Schistosoma mansoni ap endonuclease 0.0019 0.0018 0.0021
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0189 0.0716 0.2217
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0189 0.0716 0.2217
Schistosoma mansoni hypothetical protein 0.0037 0.009 0.0152
Schistosoma mansoni rab6-interacting 0.0121 0.0438 0.0788
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0021 0.0035
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0192 0.0338
Brugia malayi oxidoreductase 0.002 0.0021 0.0045
Echinococcus granulosus orexin receptor type 2 0.0135 0.0494 0.0899
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Trichomonas vaginalis apoptosis inducing factor, putative 0.0189 0.0716 0.2217
Schistosoma mansoni glutamate synthase 0.0189 0.0716 0.1296
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0083 0.0203
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0021 0.0035
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0135 0.0494 0.09
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0523 0.2088 0.5555
Schistosoma mansoni sodium/chloride dependent transporter 0.0173 0.0653 0.118
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0152 0.0145
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.0349 0.0342
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0066 0.0067
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0011 0.0004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0189 0.0716 0.2217
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0021 0.0014
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0007 0.001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0189 0.0716 0.1898
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0018 0.0049
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.0349 0.0911
Schistosoma mansoni opsin-like receptor 0.0135 0.0494 0.089
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.061 0.2447 0.6509
Brugia malayi Pre-SET motif family protein 0.01 0.0349 0.0922
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0018 0.003
Treponema pallidum NADH oxidase 0.0712 0.2864 1
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0189 0.0716 0.1853
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0021 0.0037
Echinococcus multilocularis acetylcholinesterase 0.0537 0.2144 0.3913
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0135 0.0494 0.0899
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0189 0.0716 0.1305
Echinococcus multilocularis acetylcholinesterase 0.0537 0.2144 0.3913
Schistosoma mansoni cytochrome P450 0.0019 0.0018 0.002
Brugia malayi Augmenter of liver regeneration 0.0035 0.0083 0.0212
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0349 0.0342
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0029 0.0061 0.0108
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0021 0.0025
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0066 0.0067
Schistosoma mansoni amine GPCR 0.0705 0.2838 0.5174
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni amine GPCR 0.0135 0.0494 0.089
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0021 0.0007
Onchocerca volvulus 0.0091 0.0312 0.0919
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0084 0.0229
Leishmania major C-8 sterol isomerase-like protein 0.0423 0.1677 0.1671
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0406 0.04
Schistosoma mansoni jun-related protein 0.0212 0.0809 0.1466
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0062 0.0193 0.0187
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0494 0.089
Schistosoma mansoni hypothetical protein 0.0212 0.0809 0.1466
Echinococcus multilocularis neuropeptide receptor A26 0.0135 0.0494 0.0899
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.0349 0.0634
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Entamoeba histolytica myo-inositol monophosphatase, putative 0.008 0.0268 0.3584
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.018 0.046
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0062 0.0193 0.0187
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0021 0.0009
Echinococcus multilocularis g-protein coupled receptor 0.0135 0.0494 0.0899
Onchocerca volvulus 0.0121 0.0438 0.1316
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.1158 0.3607
Leishmania major hypothetical protein, conserved 0.002 0.0021 0.0014
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0068 0.0121
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0189 0.0716 0.2452
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0021 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0152 0.0443
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0021 0.0035
Entamoeba histolytica hypothetical protein 0.0037 0.009 0.1029
Loa Loa (eye worm) programmed cell death 8 0.0189 0.0716 0.1891
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0061 0.0108
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0066 0.0175
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0066 0.0157
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0061 0.0162
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0936 0.3785 1
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0021 0.0014
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0189 0.0716 0.2451
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0021 0.0014
Echinococcus granulosus microtubule associated protein 2 0.1348 0.5478 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0135 0.0494 0.089
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0021 0.0014
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0021 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0065 0.0171
Giardia lamblia Glutamate synthase 0.0189 0.0716 0.2451
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0021 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0021 0.0014
Echinococcus multilocularis para nitrobenzyl esterase 0.0091 0.0312 0.0567
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0189 0.0716 0.1305
Entamoeba histolytica hypothetical protein 0.002 0.0021 0.0035
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0028 0.0021
Trypanosoma cruzi NADH dehydrogenase, putative 0.0189 0.0716 0.0709
Brugia malayi jmjC domain containing protein 0.0061 0.0192 0.0502
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0021 0.0031
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0135 0.0494 0.089
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0108 0.0102
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0189 0.0716 0.1891
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0135 0.0494 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Echinococcus granulosus nuclear factor of activated T cells 5 0.0159 0.0595 0.1084
Leishmania major hypothetical protein, conserved 0.002 0.0021 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0173
Schistosoma mansoni glutamate synthase 0.0189 0.0716 0.1296
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trypanosoma brucei PAB1-binding protein , putative 0.0058 0.0177 0.0171
Loa Loa (eye worm) hypothetical protein 0.0253 0.098 0.2597
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0066 0.0175
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0349 0.0914
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.0349 0.0342
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0007 0.001
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0189 0.0716 0.1891
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0021 0.0007
Schistosoma mansoni hypothetical protein 0.0094 0.0327 0.0584
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0018 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0189 0.0716 0.2217
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0108 0.0307
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0007 0.001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.0494 0.0899
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0464 0.1846 0.3369
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0029 0.0061 0.0152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0268 0.0261
Onchocerca volvulus 0.0135 0.0494 0.1492
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0494 0.0899
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0029 0.0061 0.0108
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.002 0.0021 0.0009
Brugia malayi hypothetical protein 0.0127 0.0462 0.1222
Leishmania major trypanothione reductase 0.0929 0.3756 0.3751
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0782 0.2425
Onchocerca volvulus 0.0135 0.0494 0.1492
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Brugia malayi glutamate synthase 0.0189 0.0716 0.1898
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Schistosoma mansoni growth hormone secretagogue receptor 0.0135 0.0494 0.089
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2066 0.843 0.8429
Loa Loa (eye worm) carboxylesterase 0.0091 0.0312 0.0814
Schistosoma mansoni sulfide quinone reductase 0.0189 0.0716 0.1296
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0349 0.1062
Brugia malayi hypothetical protein 0.0037 0.009 0.023
Toxoplasma gondii exonuclease III APE 0.0019 0.0018 0.003
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1891
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0021 0.001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0192 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0152 0.0443
Brugia malayi G-protein coupled receptor 0.0135 0.0494 0.1307
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0494 0.0899
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0189 0.0716 0.1891
Leishmania major hypothetical protein, conserved 0.002 0.0021 0.0014
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0189 0.0716 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Onchocerca volvulus 0.0026 0.0047 0.0082
Leishmania major cytochrome p450-like protein 0.0019 0.0018 0.0011
Brugia malayi GnHR receptor homolog 0.0135 0.0494 0.1307
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Loa Loa (eye worm) hypothetical protein 0.0091 0.0312 0.0814
Echinococcus granulosus carbonyl reductase 1 0.002 0.0021 0.0035
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0413 0.1637 0.4298
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0406 0.0739
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0029 0.0061 0.0108
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0189 0.0716 0.0709
Schistosoma mansoni sulfide quinone reductase 0.0189 0.0716 0.1296
Echinococcus granulosus single minded 2 0.0078 0.0259 0.047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Echinococcus granulosus survival motor neuron protein 1 0.0462 0.1838 0.3353
Echinococcus granulosus g protein coupled receptor 0.0135 0.0494 0.0899
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0189 0.0716 0.1906
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0152 0.0145
Schistosoma mansoni hypothetical protein 0.0121 0.0438 0.0788
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0192 0.0348
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0334 0.0608
Onchocerca volvulus 0.0074 0.0245 0.0706
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0021 0.0007
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0055 0.0099
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Schistosoma mansoni neuropeptide receptor 0.0135 0.0494 0.089
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.1158 0.3607
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0021 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0205 0.0361
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0406 0.04
Trypanosoma brucei trypanothione reductase 0.0929 0.3756 0.3751
Mycobacterium ulcerans putative regulatory protein 0.0074 0.0245 0.0797
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0029
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0189 0.0716 0.1898
Leishmania major short chain dehydrogenase-like protein 0.002 0.0021 0.0014
Toxoplasma gondii LsmAD domain-containing protein 0.0058 0.0177 0.0455
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.0494 0.1299
Brugia malayi neuropeptide F receptor 0.0135 0.0494 0.1307
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0189 0.0716 0.0709
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0021 0.0014
Leishmania major pteridine reductase 1 0.002 0.0021 0.0014
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0143
Brugia malayi Pre-SET motif family protein 0.0695 0.2797 0.7444
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0061 0.0098
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0021 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Echinococcus multilocularis transcription factor Dp 1 0.0036 0.0087 0.0156
Giardia lamblia Hypothetical protein 0.002 0.0021 0.0009
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.008 0.0268 0.0697
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Schistosoma mansoni hypothetical protein 0.0026 0.0046 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0077 0.0209
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0021 0.0045
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0192 0.0348
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0018 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0152 0.0443
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0032 0.0046
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0189 0.0716 0.1305
Brugia malayi Cytochrome P450 family protein 0.0019 0.0018 0.0038
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Brugia malayi Carboxylesterase family protein 0.0091 0.0312 0.0822
Schistosoma mansoni retinal dehydrogenase 0.002 0.0021 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Echinococcus granulosus neuropeptide receptor 0.0135 0.0494 0.0899
Schistosoma mansoni hypothetical protein 0.0189 0.0716 0.1296
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0189 0.0716 0.2451
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) hypothetical protein 0.0537 0.2144 0.5701
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.0058 0.018 0.046
Brugia malayi hypothetical protein 0.0135 0.0494 0.1307
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0189 0.0716 0.1305
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0189 0.0716 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0047 0.0113
Echinococcus granulosus oxidoreductase 0.002 0.0021 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0135 0.0494 0.1307
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0021 0.0014
Schistosoma mansoni lipoxygenase 0.0246 0.0949 0.1721
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0135 0.0494 0.0899
Onchocerca volvulus 0.0032 0.0071 0.0159
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0018 0.0039
Mycobacterium ulcerans glutamate synthase subunit beta 0.0189 0.0716 0.2452
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1811 0.738 0.7378
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0189 0.0716 0.0709
Brugia malayi jmjC domain containing protein 0.0061 0.0192 0.0502
Brugia malayi Dopamine receptor protein 1 0.0135 0.0494 0.1307
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Schistosoma mansoni steroid dehydrogenase 0.002 0.0021 0.0025
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.018 0.0469
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0009
Echinococcus granulosus allatostatin A receptor 0.0135 0.0494 0.0899
Schistosoma mansoni sodium/chloride dependent transporter 0.003 0.0064 0.0105
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Trichomonas vaginalis glutathione reductase, putative 0.0712 0.2864 0.8972
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0021 0.0007
Plasmodium vivax JmjC domain containing protein 0.0016 0.0007 0.0019
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.0494 0.0899
Trichomonas vaginalis set domain proteins, putative 0.0791 0.3191 1
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.1158 0.3607
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0192 0.0348
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0494 0.089
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0406 0.5562
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0189 0.0716 1
Loa Loa (eye worm) hypothetical protein 0.0275 0.1068 0.2831
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.008 0.0268 0.088
Mycobacterium leprae Probable oxidoreductase 0.002 0.0021 0.0007
Mycobacterium tuberculosis Probable reductase 0.0413 0.1637 0.4298
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Leishmania major NADH dehydrogenase, putative 0.0189 0.0716 0.0709
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0062 0.0193 0.0341
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0021 0.0007
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0712 0.2864 0.7626
Brugia malayi bZIP transcription factor family protein 0.026 0.101 0.2681
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.02 0.0516
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0406 0.1065
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0135 0.0494 0.0899
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0021 0.0007
Schistosoma mansoni hypothetical protein 0.0172 0.0648 0.1172
Plasmodium falciparum thioredoxin reductase 0.0929 0.3756 1
Loa Loa (eye worm) hypothetical protein 0.0121 0.0438 0.115
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0349 0.0624
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0135 0.0494 0.0899
Brugia malayi cytochrome P450 0.0019 0.0018 0.0038
Trichomonas vaginalis spcc417.12 protein, putative 0.0091 0.0312 0.0948
Plasmodium vivax thioredoxin reductase, putative 0.0929 0.3756 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0135 0.0494 0.1307
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0189 0.0716 0.1853
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Echinococcus granulosus alpha 1A adrenergic receptor 0.0135 0.0494 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0189 0.0716 0.2217
Echinococcus multilocularis lipoxygenase domain containing protein 0.0121 0.0438 0.0798
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0018 0.003
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0021 0.0035
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0189 0.0716 0.0709
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0068 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0365 0.1439 0.3821
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0021 0.001
Loa Loa (eye worm) oxidoreductase 0.002 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.0494 0.089
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0021 0.0035
Loa Loa (eye worm) serotonin transporter b 0.0173 0.0653 0.1722
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0135 0.0494 0.0899
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0021 0.0014
Brugia malayi hypothetical protein 0.0037 0.0093 0.0238
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0061 0.0098
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0061 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0054 0.0136
Onchocerca volvulus 0.0135 0.0494 0.1492
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0091 0.0312 0.0781
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.1158 0.3607
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.0494 0.1299
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Echinococcus granulosus somatostatin receptor 0.0135 0.0494 0.0899
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0051 0.0044
Schistosoma mansoni sodium-dependent amino acid transporter 0.0029 0.0061 0.0098
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0712 0.2864 1
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0021 0.0014
Schistosoma mansoni ap endonuclease 0.0019 0.0018 0.0021
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0018 0.003
Giardia lamblia Kinase, CMGC MAPK 0.01 0.0349 0.1161
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0055 0.0099
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0062 0.0193 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0021 0.0014
Loa Loa (eye worm) inositol-1 0.008 0.0268 0.0697
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0021 0.0014
Mycobacterium ulcerans carboxylesterase, LipT 0.0091 0.0312 0.1034
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0051 0.0044
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0062 0.0193 0.0506
Brugia malayi sulfakinin receptor protein 0.0135 0.0494 0.1307
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0494 0.089
Loa Loa (eye worm) melatonin receptor type 1A 0.0135 0.0494 0.1299
Echinococcus granulosus acetylcholinesterase 0.0537 0.2144 0.3913
Leishmania major hypothetical protein, conserved 0.0189 0.0716 0.0709
Echinococcus multilocularis survival motor neuron protein 1 0.0462 0.1838 0.3353
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0021 0.0035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0152 0.0394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2066 0.843 0.8429
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0018 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0494 0.0899
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0406 0.1244
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.009 0.0152
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0177 0.0455
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0037
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0018 0.003
Chlamydia trachomatis thioredoxin reductase 0.0189 0.0716 0.2375
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Echinococcus granulosus neuropeptide s receptor 0.0135 0.0494 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0272
Toxoplasma gondii thioredoxin reductase 0.0929 0.3756 1
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0021 0.0035
Schistosoma mansoni carbonyl reductase 0.002 0.0021 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0135 0.0494 0.0899
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.002 0.0021 0.0007
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0135 0.0494 0.0899
Echinococcus multilocularis neuropeptide FF receptor 2 0.0135 0.0494 0.0899
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0021 0.0045
Echinococcus granulosus geminin 0.0172 0.0648 0.1181
Mycobacterium ulcerans monoxygenase 0.0189 0.0716 0.2452
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0047 0.0083
Plasmodium falciparum transporter, putative 0.0029 0.0061 0.0143
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0018 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0189 0.0716 0.0709
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0021 0.0007
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Echinococcus granulosus neuropeptide receptor A26 0.0135 0.0494 0.0899
Echinococcus multilocularis conserved hypothetical protein 0.0792 0.3195 0.5831
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0068 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0739 0.2289
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0135 0.0494 0.1299
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0021 0.001
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0156 0.0272
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0047 0.0083
Schistosoma mansoni biogenic amine receptor 0.0135 0.0494 0.089
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0018 0.003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0021 0.0025
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0072 0.0234 0.0573
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0021 0.0007
Echinococcus granulosus carbonyl reductase 1 0.002 0.0021 0.0035

Activities

Activity type Activity value Assay description Source Reference
logD (ADMET) = 1.74 Partition coefficient (logD7.4) ChEMBL. 12639566
Papp (ADMET) = 71900000 cm s-1 Permeability coefficient (Papp) (Caco-2 cell monolayer) ChEMBL. 12639566

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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