Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0131 | 0.0865 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0271 | 0.2653 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0105 | 0.1578 |
Onchocerca volvulus | 0.0131 | 0.0865 | 0.5399 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0131 | 0.0865 | 0.0865 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0008 | 0.0008 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0008 | 0.0008 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0059 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0304 | 0.2082 | 0.2082 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0008 | 0.0008 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0142 | 0.4029 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0194 | 0.0358 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0776 | 0.5407 | 0.5407 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0059 | 0.0108 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | carboxylesterase | 0.0131 | 0.0865 | 0.1601 |
Echinococcus granulosus | snurportin 1 | 0.0304 | 0.2082 | 0.2082 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0776 | 0.5407 | 0.5407 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0017 | 0.0031 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0017 | 0.0017 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0017 | 0.0017 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0131 | 0.0865 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0017 | 0.0017 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0008 | 0.0014 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0008 | 0.0008 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0142 | 0.4029 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0364 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0017 | 0.0017 |
Onchocerca volvulus | 0.0131 | 0.0865 | 0.5399 | |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | hypothetical protein | 0.0233 | 0.1586 | 0.2933 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0017 | 0.0031 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0271 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0017 | 0.0031 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0215 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | carboxylesterase | 0.0131 | 0.0865 | 0.1601 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0215 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0271 | 0.0501 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0008 | 0.0014 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0016 | 0.0056 | 0.5 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0105 | 0.2264 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0151 | 0.0151 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0151 | 0.0278 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.0017 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0017 | 0.0031 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0142 | 0.4029 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0271 | 0.697 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0364 | 0.0364 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.0793 | 0.1466 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0277 | 0.0277 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0215 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.1586 | 0.2933 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0271 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0151 | 0.0151 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0776 | 0.5407 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0017 | 0.0031 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0017 | 0.0017 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0008 | 0.0014 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0105 | 0.0316 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0017 | 0.0031 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.1586 | 0.1586 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0304 | 0.2082 | 0.385 |
Mycobacterium tuberculosis | Probable reductase | 0.0106 | 0.0692 | 0.7854 |
Onchocerca volvulus | 0.0131 | 0.0865 | 0.5399 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0017 | 0.0031 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0143 | 0.0143 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0017 | 0.0017 |
Onchocerca volvulus | 0.0131 | 0.0865 | 0.5399 | |
Schistosoma mansoni | microtubule-associated protein tau | 0.1428 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0017 | 0.0017 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0364 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.0017 | 0.0057 |
Brugia malayi | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0056 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0131 | 0.0865 | 0.5255 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0215 | 0.0398 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0106 | 0.0692 | 0.7854 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0271 | 0.0271 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0017 | 0.0017 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0008 | 0.0008 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0364 | 0.0364 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0271 | 0.0501 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0151 | 0.0151 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0277 | 0.0277 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0056 | 0.0056 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0017 | 0.0031 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0008 | 0.0008 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0142 | 0.0263 |
Echinococcus granulosus | acetylcholinesterase | 0.0776 | 0.5407 | 0.5407 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0364 | 0.3807 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0142 | 0.0142 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0105 | 0.0316 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0017 | 0.0031 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0008 | 0.0008 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0008 | 0.0008 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0776 | 0.5407 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0118 | 0.0775 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.031 | 0.0574 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0131 | 0.0865 | 0.0865 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0017 | 0.0017 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0017 | 0.0017 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0364 | 0.3807 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0059 | 0.0059 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0131 | 0.0865 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0056 | 0.0103 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0776 | 0.5407 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0056 | 0.0056 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0151 | 0.0151 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0059 | 0.0108 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0056 | 0.0056 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0056 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0008 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0194 | 0.0358 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 0.0692 | 0.7854 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 0.0865 | 0.1601 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0106 | 0.0692 | 0.7854 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.1275 | 0.2358 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0215 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0194 | 0.0194 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0215 | 0.0215 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 0.0865 | 0.1601 |
Schistosoma mansoni | acetylcholinesterase | 0.0131 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0271 | 0.0501 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0017 | 0.0031 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0106 | 0.0692 | 0.7854 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0008 | 0.0014 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0008 | 0.0014 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0059 | 0.0059 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0142 | 0.0142 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0364 | 0.3807 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0271 | 0.738 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.031 | 0.0574 |
Echinococcus granulosus | acetylcholinesterase | 0.0776 | 0.5407 | 0.5407 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0017 | 0.0031 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Echinococcus granulosus | carboxylesterase 5A | 0.0776 | 0.5407 | 0.5407 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.0793 | 0.1466 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.1586 | 0.1586 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0059 | 0.0059 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0017 | 0.0017 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0118 | 0.0775 | 0.8888 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0059 | 0.0108 |
Echinococcus multilocularis | acetylcholinesterase | 0.0776 | 0.5407 | 0.5407 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0189 | 0.1275 | 0.7978 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0017 | 0.0017 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0271 | 0.0271 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0017 | 0.0031 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1428 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0017 | 0.0017 |
Echinococcus multilocularis | snurportin 1 | 0.0304 | 0.2082 | 0.2082 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0017 | 0.0017 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0017 | 0.0031 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0271 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0151 | 0.0278 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0017 | 0.0017 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0017 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0008 | 0.0014 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0271 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0215 | 0.0215 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0131 | 0.0865 | 0.0865 |
Onchocerca volvulus | 0.003 | 0.0151 | 0.0899 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 0.1596 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0151 | 0.4008 |
Echinococcus multilocularis | neuroligin | 0.0131 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.0793 | 0.1466 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0271 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0017 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0059 | 0.0059 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0271 | 0.0501 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0056 | 0.1354 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0131 | 0.0865 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0008 | 0.0008 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0017 | 0.0017 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0056 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0008 | 0.0008 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0026 | 0.0048 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.1396 | 0.2581 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0026 | 0.0048 |
Echinococcus multilocularis | acetylcholinesterase | 0.0776 | 0.5407 | 0.5407 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0118 | 0.0775 | 0.8888 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0106 | 0.0692 | 0.7854 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0017 | 0.0017 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0105 | 0.0316 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0271 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0131 | 0.0865 | 0.0865 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0008 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0017 | 0.0031 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0059 | 0.0059 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.1396 | 0.2581 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.0017 | 0.0057 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0059 | 0.0108 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0008 | 0.0014 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0364 | 0.3807 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0056 | 0.1354 |
Loa Loa (eye worm) | carboxylesterase | 0.0776 | 0.5407 | 1 |
Onchocerca volvulus | 0.0048 | 0.0277 | 0.1697 | |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0151 | 0.4404 |
Onchocerca volvulus | 0.0011 | 0.0017 | 0.0057 | |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0142 | 0.4029 |
Echinococcus granulosus | neuroligin | 0.0131 | 0.0865 | 0.0865 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0059 | 0.0059 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0008 | 0.0008 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 0.0865 | 0.1601 |
Brugia malayi | Carboxylesterase family protein | 0.0776 | 0.5407 | 1 |
Onchocerca volvulus | 0.0235 | 0.1596 | 1 | |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0142 | 0.3782 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0277 | 0.0513 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0364 | 0.0364 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0017 | 0.0017 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0017 | 0.0031 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0131 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.031 | 0.0574 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0017 | 0.0031 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0131 | 0.0865 | 0.5255 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0008 | 0.0014 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 0.0865 | 0.1601 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0059 | 0.0059 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0056 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0142 | 0.0263 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0118 | 0.0775 | 0.8888 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0008 | 0.0008 |
Brugia malayi | N-terminal motif family protein | 0.0189 | 0.1275 | 0.2358 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0215 | 0.0215 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0008 | 0.0008 |
Schistosoma mansoni | gliotactin | 0.0131 | 0.0865 | 0.0865 |
Brugia malayi | Carboxylesterase family protein | 0.0776 | 0.5407 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0017 | 0.0017 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0017 | 0.0031 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.0512 | 0.0947 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0008 | 0.0014 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.031 | 0.0574 |
Onchocerca volvulus | 0.0131 | 0.0865 | 0.5399 | |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0865 | 0.1601 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Reduction (functional) | = -7 % | Tested for its effect on testes weight 3 days after single oral dose (90 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = -5 % | Tested for its effect on testes weight 3 days after single oral dose (3 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = -3 % | Tested for its effect on testes weight 3 days after single sub cutaneous (10 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 0 % | Tested for its effect on spermatogenic index 3 days after single oral dose (90 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 2 % | Tested for its effect on spermatogenic index 3 days after single oral dose (3 mg/kg) , | ChEMBL. | 7877141 |
Reduction (functional) | = 5 % | Tested for its effect on testes weight 3 days after single sub cutaneous dose (3 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 8 % | Tested for its effect on spermatogenic index 3 days after single sub cutaneous dose (3 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 13 % | Tested for its effect on testes weight 3 days after single oral dose (3 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 16 % | Tested for its effect on testes weight 3 days after single oral dose (30 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 17 % | Tested for its effect on testes weight 3 days after single single sub cutaneous dose (30 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 21 % | Tested for its effect on spermatogenic index 3 days after single oral dose (3 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 24 % | Tested for its effect on testes weight 3 days after single oral dose (10 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 26 % | Tested for its effect on testes weight 3 days after single oral dose (10 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 27 % | Tested for its effect on testes weight 3 days after single oral dose (90 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 27 % | Tested for its effect on spermatogenic index 3 days after single sub cutaneous dose (10 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 28 % | Tested for its effect on testes weight 3 days after single oral dose (30 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 35 % | Tested for its effect on spermatogenic index 3 days after single oral dose (30 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 36 % | Tested for its effect on spermatogenic index 3 days after single oral dose (10 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 40 % | Tested for its effect on spermatogenic index 3 days after single oral dose (10 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 51 % | Tested for its effect on spermatogenic index 3 days after single oral dose (30 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 67 % | Tested for its effect on spermatogenic index 3 days after single oral dose (30 mg/kg) | ChEMBL. | 7877141 |
Reduction (functional) | = 70 % | Tested for its effect on spermatogenic index 3 days after single oral dose (90 mg/kg) | ChEMBL. | 7877141 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.