Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0043 | 0.0119 | 0.1939 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0119 | 0.1939 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0015 | 0.0056 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.004 | 0.0262 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0045 | 0.013 | 0.0128 |
Brugia malayi | tailless protein | 0.0084 | 0.0306 | 0.104 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0093 | 0.1439 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0052 | 0.0162 | 0.1057 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0178 | 0.073 | 0.0754 |
Brugia malayi | Importin beta-1 subunit | 0.0061 | 0.0203 | 0.0683 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0026 | 0.0026 |
Echinococcus multilocularis | geminin | 0.0511 | 0.2231 | 0.2324 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0015 | 0.0007 |
Schistosoma mansoni | hypothetical protein | 0.0655 | 0.2879 | 0.2879 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0093 | 0.0297 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0356 | 0.1534 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0178 | 0.073 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0012 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0169 | 0.0687 | 0.4481 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0019 | 0.0037 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0192 | 0.0794 | 0.0821 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.013 | 0.085 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0052 | 0.0162 | 0.2533 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Leishmania major | importin beta-1 subunit, putative | 0.005 | 0.0151 | 0.0985 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0019 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0351 | 0.1194 |
Brugia malayi | hypothetical protein | 0.0094 | 0.0351 | 0.1199 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0045 | 0.013 | 0.1603 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0052 | 0.0162 | 0.2533 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.004 | 0.0113 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0015 | 0.0024 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0043 | 0.0119 | 0.1939 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0129 | 0.0129 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0084 | 0.0306 | 0.0298 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0008 | 0.0008 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0382 | 0.1649 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | biogenic amine receptor | 0.0018 | 0.0008 | 0.0008 |
Plasmodium vivax | importin-beta 2, putative | 0.0061 | 0.0203 | 0.3227 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0043 | 0.0119 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0052 | 0.0162 | 0.1977 |
Loa Loa (eye worm) | hypothetical protein | 0.0652 | 0.2869 | 0.9964 |
Brugia malayi | sulfakinin receptor protein | 0.0652 | 0.2869 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0178 | 0.073 | 0.073 |
Echinococcus multilocularis | RUN | 0.002 | 0.0015 | 0.0007 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0178 | 0.073 | 0.073 |
Schistosoma mansoni | hypothetical protein | 0.0511 | 0.2231 | 0.2231 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.004 | 0.0258 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0084 | 0.0306 | 0.0306 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.005 | 0.0151 | 0.2555 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.013 | 0.0515 | 0.0507 |
Schistosoma mansoni | coup transcription factor | 0.0178 | 0.073 | 0.073 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0038 | 0.01 | 0.032 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0178 | 0.073 | 0.0754 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0076 | 0.0076 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.004 | 0.0262 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0052 | 0.0162 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0382 | 0.1649 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0192 | 0.0794 | 0.0821 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0119 | 0.1939 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.013 | 0.085 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0055 | 0.0173 | 0.0166 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0343 | 0.1476 | 0.8947 |
Echinococcus granulosus | tumor protein p63 | 0.0358 | 0.1544 | 0.1537 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0019 | 0.0011 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0019 | 0.0122 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0052 | 0.0162 | 0.1057 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.0496 | 0.1705 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0026 | 0.0061 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0037 | 0.0093 | 0.0949 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0178 | 0.073 | 0.0754 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0018 | 0.0008 | 0.0008 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0101 | 0.1592 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0045 | 0.0129 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0084 | 0.0306 | 0.0311 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.2139 | 0.9576 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0178 | 0.073 | 0.0722 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Brugia malayi | Bromodomain containing protein | 0.0091 | 0.0336 | 0.1145 |
Schistosoma mansoni | ran | 0.0045 | 0.013 | 0.013 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | nuclear receptor | 0.0084 | 0.0306 | 0.0306 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.005 | 0.0153 | 0.0996 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0178 | 0.073 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0178 | 0.073 | 0.073 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0084 | 0.0306 | 0.0311 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0188 | 0.0773 | 0.4667 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0178 | 0.073 | 0.0722 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0037 | 0.0093 | 0.0608 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0047 | 0.0137 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0015 | 0.0007 |
Plasmodium vivax | glutathione reductase, putative | 0.0151 | 0.0606 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0343 | 0.1476 | 0.8947 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0129 | 0.0126 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0047 | 0.0137 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0135 | 0.0537 | 1 |
Leishmania major | GTP-binding protein, putative | 0.0045 | 0.013 | 0.085 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0045 | 0.013 | 0.1998 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.013 | 0.0426 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0052 | 0.0162 | 0.2165 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0047 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0015 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0145 | 0.0476 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0084 | 0.0306 | 0.1036 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0047 | 0.0041 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0052 | 0.0162 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0351 | 0.1194 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0052 | 0.0162 | 0.1057 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0135 | 0.0537 | 0.8832 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0094 | 0.0351 | 0.1199 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0135 | 0.0537 | 0.0529 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0084 | 0.0306 | 0.104 |
Toxoplasma gondii | hypothetical protein | 0.0057 | 0.0186 | 0.2586 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.013 | 0.0515 | 0.8393 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0178 | 0.073 | 0.0754 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.004 | 0.0377 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0015 | 0.0007 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0052 | 0.0162 | 0.2769 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0015 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0172 | 0.057 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0438 | 0.1905 | 0.1898 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.011 | 0.0356 |
Schistosoma mansoni | thyroid hormone receptor | 0.0178 | 0.073 | 0.073 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0018 | 0.0008 | 0.0008 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0052 | 0.0162 | 0.1977 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0178 | 0.073 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0012 | 0.0028 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0039 | 0.0101 | 0.0093 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.005 | 0.0153 | 0.0996 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0093 | 0.0298 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0019 | 0.0095 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.004 | 0.0262 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0094 | 0.0351 | 0.1199 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0178 | 0.073 | 0.2514 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0192 | 0.0794 | 0.2736 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0178 | 0.073 | 0.2523 |
Brugia malayi | glutathione reductase | 0.0151 | 0.0606 | 0.209 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0084 | 0.0306 | 0.104 |
Schistosoma mansoni | lamin | 0.0027 | 0.0047 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0018 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0382 | 0.1649 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0084 | 0.0306 | 0.0306 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | amine GPCR | 0.0018 | 0.0008 | 0.0008 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0074 | 0.0262 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.004 | 0.011 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0122 | 0.0475 | 1 |
Onchocerca volvulus | 0.0025 | 0.004 | 0.0446 | |
Onchocerca volvulus | 0.0111 | 0.0428 | 0.5821 | |
Loa Loa (eye worm) | thioredoxin reductase | 0.0151 | 0.0606 | 0.2082 |
Onchocerca volvulus | 0.0178 | 0.073 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0351 | 0.1194 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0039 | 0.0101 | 0.0325 |
Schistosoma mansoni | bromodomain containing protein | 0.0078 | 0.0279 | 0.0279 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0039 | 0.0101 | 0.0324 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0178 | 0.073 | 0.073 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0178 | 0.073 | 0.073 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0047 | 0.0039 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0035 | 0.0035 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0043 | 0.0119 | 0.0777 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0052 | 0.0162 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0084 | 0.0306 | 0.104 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.004 | 0.0258 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0047 | 0.0039 |
Echinococcus granulosus | RUN | 0.002 | 0.0015 | 0.0007 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0094 | 0.0351 | 0.0351 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0084 | 0.0306 | 0.0306 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0119 | 0.0777 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0163 | 0.0541 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | ran | 0.0045 | 0.013 | 0.013 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0039 | 0.0101 | 0.1176 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0052 | 0.0162 | 1 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0052 | 0.0162 | 0.0945 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.0496 | 0.1699 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0382 | 0.1649 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0052 | 0.0162 | 0.2769 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Brugia malayi | ecdysone receptor | 0.0084 | 0.0306 | 0.104 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0084 | 0.0306 | 0.0306 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.013 | 0.1998 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0094 | 0.0351 | 0.0351 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0019 | 0.0122 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.004 | 0.0377 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0047 | 0.0041 |
Schistosoma mansoni | nuclear hormone receptor | 0.0084 | 0.0306 | 0.0306 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0019 | 0.0122 |
Loa Loa (eye worm) | DR-78 | 0.0084 | 0.0306 | 0.1036 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0019 | 0.0122 |
Onchocerca volvulus | 0.0084 | 0.0306 | 0.4122 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0178 | 0.073 | 0.0754 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0178 | 0.073 | 0.2523 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0084 | 0.0306 | 0.104 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.005 | 0.0151 | 0.2555 |
Mycobacterium ulcerans | hypothetical protein | 0.0188 | 0.0773 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0074 | 0.0262 | 0.0266 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0084 | 0.0306 | 0.1036 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0356 | 0.1534 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | amine GPCR | 0.0018 | 0.0008 | 0.0008 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0135 | 0.0537 | 0.8774 |
Plasmodium falciparum | glutathione reductase | 0.0151 | 0.0606 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0178 | 0.073 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0084 | 0.0306 | 0.0298 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0454 | 0.1973 | 0.1973 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0093 | 0.0608 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0052 | 0.0162 | 0.2533 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.004 | 0.0377 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0306 | 0.104 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.013 | 0.0515 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0351 | 0.1194 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0099 | 0.0091 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.013 | 0.0515 | 0.6608 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.005 | 0.0151 | 0.0985 |
Echinococcus multilocularis | tumor protein p63 | 0.0358 | 0.1544 | 0.1605 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0039 | 0.0101 | 0.0097 |
Brugia malayi | nuclear hormone receptor | 0.0084 | 0.0306 | 0.104 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0043 | 0.0119 | 0.1939 |
Schistosoma mansoni | neuropeptide receptor | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0084 | 0.0306 | 0.0311 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Trypanosoma brucei | glucosidase, putative | 0.0043 | 0.0119 | 0.0777 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0169 | 0.0687 | 0.4481 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0094 | 0.0351 | 0.1194 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0012 |
Trichomonas vaginalis | importin beta-1, putative | 0.005 | 0.0151 | 0.2555 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0129 | 0.0421 |
Brugia malayi | hypothetical protein | 0.0025 | 0.004 | 0.011 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0343 | 0.1476 | 0.8947 |
Schistosoma mansoni | nuclear hormone receptor | 0.0178 | 0.073 | 0.073 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0178 | 0.073 | 0.2514 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0178 | 0.073 | 0.2514 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0019 | 0.0037 |
Schistosoma mansoni | opsin-like receptor | 0.0018 | 0.0008 | 0.0008 |
Echinococcus granulosus | lamin | 0.0027 | 0.0047 | 0.0039 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0084 | 0.0306 | 0.4122 |
Plasmodium falciparum | thioredoxin reductase | 0.0151 | 0.0606 | 1 |
Schistosoma mansoni | amine GPCR | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.013 | 0.0515 | 0.053 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0151 | 0.0606 | 0.3951 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Brugia malayi | ecdysteroid receptor | 0.0178 | 0.073 | 0.2523 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.004 | 0.0377 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.2233 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0178 | 0.073 | 0.073 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.013 | 0.0515 | 0.3357 |
Brugia malayi | nuclear receptor RXR | 0.0084 | 0.0306 | 0.104 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0093 | 0.1439 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0129 | 0.0121 |
Brugia malayi | RNA, U transporter 1 | 0.0174 | 0.0713 | 0.2465 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0084 | 0.0306 | 0.104 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | nuclear receptor | 0.0084 | 0.0306 | 0.0306 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0019 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0015 | 0.0015 |
Schistosoma mansoni | alpha-glucosidase | 0.0165 | 0.0673 | 0.0673 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0178 | 0.073 | 0.0722 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0008 | 0.0008 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0192 | 0.0794 | 0.0786 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.004 | 0.0112 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0655 | 0.2879 | 1 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0037 | 0.0093 | 0.1632 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0015 | 0.0007 |
Echinococcus granulosus | geminin | 0.0511 | 0.2231 | 0.2225 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.004 | 0.0203 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0052 | 0.0162 | 0.2533 |
Loa Loa (eye worm) | acetyltransferase | 0.0454 | 0.1973 | 0.6844 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Toxoplasma gondii | thioredoxin reductase | 0.0151 | 0.0606 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0178 | 0.073 | 0.2514 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0454 | 0.1973 | 0.6868 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.004 | 0.0377 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0178 | 0.073 | 0.2523 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0061 | 0.0203 | 0.1326 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0178 | 0.073 | 0.0754 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0019 | 0.0019 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0343 | 0.1476 | 0.8925 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0012 |
Echinococcus granulosus | importin subunit beta 1 | 0.0061 | 0.0203 | 0.0195 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0084 | 0.0306 | 0.0298 |
Entamoeba histolytica | Ran family GTPase | 0.0045 | 0.013 | 0.2444 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0055 | 0.0173 | 0.0173 |
Brugia malayi | nuclear receptor NHR-88 | 0.0084 | 0.0306 | 0.104 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Schistosoma mansoni | hypothetical protein | 0.0511 | 0.2231 | 0.2231 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.004 | 0.047 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0019 | 0.0019 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0192 | 0.0794 | 0.2746 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0039 | 0.0101 | 0.066 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0145 | 0.0478 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0047 | 0.0137 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0151 | 0.0609 | 0.0628 |
Echinococcus multilocularis | zinc finger protein | 0.0032 | 0.007 | 0.0065 |
Onchocerca volvulus | 0.0027 | 0.0047 | 0.0543 | |
Schistosoma mansoni | biogenic amine receptor | 0.0018 | 0.0008 | 0.0008 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0178 | 0.073 | 0.2523 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Schistosoma mansoni | lipoxygenase | 0.002 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0012 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.013 | 0.085 |
Schistosoma mansoni | adenoreceptor | 0.0018 | 0.0008 | 0.0008 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0052 | 0.0162 | 0.314 |
Onchocerca volvulus | 0.0027 | 0.0047 | 0.0543 | |
Plasmodium falciparum | glutathione reductase | 0.0052 | 0.0162 | 0.2533 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0037 | 0.0093 | 0.1375 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.0163 | 0.0163 |
Brugia malayi | PHD-finger family protein | 0.0037 | 0.0096 | 0.0307 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0043 | 0.0119 | 0.0116 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0061 | 0.0203 | 0.0204 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0039 | 0.0101 | 0.1805 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0038 | 0.01 | 0.032 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0037 | 0.0093 | 0.0085 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0135 | 0.0537 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0094 | 0.0351 | 0.0343 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0084 | 0.0306 | 0.104 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0037 | 0.0093 | 0.0608 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0178 | 0.073 | 0.2514 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0178 | 0.073 | 0.2523 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0019 | 0.0037 |
Schistosoma mansoni | opsin-like receptor | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.004 | 0.0113 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0047 | 0.0047 |
Toxoplasma gondii | exonuclease III APE | 0.0039 | 0.0101 | 0.1088 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0035 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0178 | 0.073 | 0.2523 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0178 | 0.073 | 0.2514 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0178 | 0.073 | 0.0754 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0101 | 0.1508 |
Brugia malayi | Bromodomain containing protein | 0.0052 | 0.016 | 0.0531 |
Schistosoma mansoni | amine GPCR | 0.0018 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0151 | 0.0606 | 0.3648 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0019 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.004 | 0.0112 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.013 | 0.2444 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0076 | 0.0237 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0015 | 0.0024 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0039 | 0.0101 | 0.0574 |
Plasmodium falciparum | thioredoxin reductase | 0.0052 | 0.0162 | 0.2533 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.002 | 0.0015 | 0.0007 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0101 | 0.1508 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0043 | 0.0119 | 0.0111 |
Schistosoma mansoni | amine GPCR | 0.0018 | 0.0008 | 0.0008 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0043 | 0.0119 | 0.2199 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0122 | 0.0475 | 0.7802 |
Schistosoma mansoni | neuropeptide receptor | 0.0018 | 0.0008 | 0.0008 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0035 | 0.0027 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.004 | 0.0377 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.013 | 0.0515 | 0.3094 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0343 | 0.1476 | 0.8947 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0084 | 0.0306 | 0.0298 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0019 | 0.0011 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0019 | 0.0011 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0129 | 0.0129 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.013 | 0.0427 |
Brugia malayi | hypothetical protein | 0.0094 | 0.0351 | 0.1199 |
Echinococcus granulosus | zinc finger protein | 0.0032 | 0.007 | 0.0062 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0151 | 0.0606 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0246 | 0.1036 | 0.358 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.004 | 0.0203 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.0496 | 0.1699 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.004 | 0.047 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0178 | 0.073 | 0.2523 |
Loa Loa (eye worm) | glutathione reductase | 0.0151 | 0.0606 | 0.2082 |
Brugia malayi | hypothetical protein | 0.0652 | 0.2869 | 1 |
Onchocerca volvulus | 0.002 | 0.0015 | 0.0095 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0181 | 0.0601 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0129 | 0.0129 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0037 | 0.0093 | 0.0608 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0052 | 0.0162 | 0.1057 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.004 | 0.0471 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0043 | 0.0119 | 0.1939 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0052 | 0.0162 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0094 | 0.0351 | 0.0358 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0454 | 0.1973 | 0.2054 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0119 | 0.1939 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.004 | 0.0258 |
Brugia malayi | hypothetical protein | 0.002 | 0.0015 | 0.0024 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0122 | 0.0475 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0052 | 0.0162 | 0.1057 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0178 | 0.073 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0178 | 0.073 | 0.2514 |
Treponema pallidum | NADH oxidase | 0.0052 | 0.0162 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.004 | 0.0471 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.004 | 0.047 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0045 | 0.013 | 0.0122 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0052 | 0.0162 | 0.1977 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0018 | 0.0008 | 0.0008 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0101 | 0.066 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0052 | 0.0162 | 0.0162 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0093 | 0.0298 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0169 | 0.0687 | 0.4481 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | myosin xvIII | 0.0018 | 0.0008 | 0.0008 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.013 | 0.0515 | 0.6608 |
Plasmodium falciparum | importin beta, putative | 0.0061 | 0.0203 | 0.3227 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.004 | 0.0113 |
Mycobacterium tuberculosis | Probable reductase | 0.0343 | 0.1476 | 0.8947 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0178 | 0.073 | 0.0722 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.013 | 0.0515 | 0.0515 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.004 | 0.0377 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0084 | 0.0306 | 0.0311 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0178 | 0.073 | 0.0754 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0178 | 0.073 | 0.2523 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0356 | 0.1534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0047 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0351 | 0.1194 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0043 | 0.0119 | 0.0387 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0306 | 0.104 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.013 | 0.0515 | 0.6608 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Onchocerca volvulus | 0.002 | 0.0015 | 0.0095 | |
Onchocerca volvulus | 0.0084 | 0.0306 | 0.4122 | |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0178 | 0.073 | 0.2514 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0019 | 0.0122 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0019 | 0.0019 |
Trypanosoma brucei | trypanothione reductase | 0.0151 | 0.0606 | 0.3951 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0043 | 0.0119 | 0.1406 |
Echinococcus granulosus | snurportin 1 | 0.0655 | 0.2879 | 0.2874 |
Echinococcus multilocularis | snurportin 1 | 0.0655 | 0.2879 | 0.3001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | neuropeptide receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | alpha glucosidase | 0.0043 | 0.0119 | 0.0119 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0084 | 0.0306 | 0.0298 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0019 | 0.0011 |
Schistosoma mansoni | importin beta-1 | 0.0061 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.073 | 0.2514 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0135 | 0.0537 | 0.8774 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0178 | 0.073 | 0.2523 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0178 | 0.073 | 0.073 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0119 | 0.1939 |
Brugia malayi | Thioredoxin reductase | 0.0151 | 0.0606 | 0.209 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0151 | 0.0609 | 0.0601 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0037 | 0.0093 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0008 | 0.0008 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0039 | 0.0101 | 0.1805 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0052 | 0.0162 | 0.1057 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.005 | 0.0153 | 0.0996 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0129 | 0.0422 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0015 | 0.0015 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0084 | 0.0306 | 0.0311 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0101 | 0.0101 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0039 | 0.0101 | 0.066 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0084 | 0.0306 | 0.1036 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0012 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0052 | 0.0162 | 0.0154 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0129 | 0.0126 |
Trichomonas vaginalis | ran, putative | 0.0045 | 0.013 | 0.2155 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0119 | 0.0777 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0037 | 0.0093 | 0.0093 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0178 | 0.073 | 0.2523 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0076 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0265 | 0.0896 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0084 | 0.0306 | 0.4122 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0008 | 0.0001 |
Schistosoma mansoni | neuropeptide receptor | 0.0018 | 0.0008 | 0.0008 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0052 | 0.0162 | 0.1057 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0052 | 0.0162 | 0.2165 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0356 | 0.1534 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0008 | 0.0008 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0129 | 0.0121 |
Leishmania major | trypanothione reductase | 0.0151 | 0.0606 | 0.3951 |
Schistosoma mansoni | histamine h1 receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0018 | 0.0008 | 0.0008 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0043 | 0.0119 | 0.2199 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0018 | 0.0008 | 0.0008 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0178 | 0.073 | 0.073 |
Schistosoma mansoni | lamin | 0.0027 | 0.0047 | 0.0047 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.004 | 0.0258 |
Brugia malayi | steroid hormone receptor | 0.0178 | 0.073 | 0.2523 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.004 | 0.0471 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0099 | 0.0095 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0119 | 0.1939 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0178 | 0.073 | 0.0722 |
Schistosoma mansoni | alpha-glucosidase | 0.0165 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0306 | 0.1036 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.002 | 0.0015 | 0.0007 |
Brugia malayi | nuclear hormone receptor | 0.0178 | 0.073 | 0.2523 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0037 | 0.0093 | 0.0297 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0061 | 0.0203 | 0.1326 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0101 | 0.066 |
Schistosoma mansoni | polycystin 1-related | 0.002 | 0.0015 | 0.0015 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0343 | 0.1476 | 0.8947 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0203 | 0.068 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0052 | 0.0162 | 0.0161 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0019 | 0.0122 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0178 | 0.073 | 0.0722 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0101 | 0.1592 |
Brugia malayi | hypothetical protein | 0.002 | 0.0015 | 0.0024 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0145 | 0.0476 |
Schistosoma mansoni | zinc finger protein | 0.0084 | 0.0306 | 0.0306 |
Brugia malayi | nuclear receptor RXR | 0.0094 | 0.0351 | 0.1199 |
Onchocerca volvulus | 0.0052 | 0.0163 | 0.2153 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0019 | 0.0122 |
Schistosoma mansoni | biogenic amine receptor | 0.0018 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.004 | 0.0112 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0084 | 0.0306 | 0.104 |
Loa Loa (eye worm) | bromodomain containing protein | 0.003 | 0.0061 | 0.0185 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0015 | 0.0015 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0018 | 0.0008 | 0.0008 |
Brugia malayi | nuclear receptor NHR-67 | 0.0084 | 0.0306 | 0.104 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.0153 | 0.0996 |
Schistosoma mansoni | opsin-like receptor | 0.0018 | 0.0008 | 0.0008 |
Entamoeba histolytica | hypothetical protein | 0.005 | 0.0151 | 0.2897 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0084 | 0.0306 | 0.0298 |
Schistosoma mansoni | lipoxygenase | 0.0055 | 0.0173 | 0.0173 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0145 | 0.0478 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0178 | 0.073 | 0.0722 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0018 | 0.0008 | 0.0008 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0178 | 0.073 | 0.2523 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0037 | 0.0093 | 0.1375 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0019 | 0.0072 |
Echinococcus granulosus | FTZ F1 alpha | 0.0178 | 0.073 | 0.0722 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0061 | 0.0203 | 0.2892 |
Brugia malayi | follicle stimulating hormone receptor | 0.0246 | 0.1036 | 0.3593 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.004 | 0.0377 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0019 | 0.0072 |
Schistosoma mansoni | loxhd1 | 0.002 | 0.0015 | 0.0015 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0019 | 0.0037 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0019 | 0.0122 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0061 | 0.0202 | 0.1318 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0047 | 0.0137 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0019 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0015 | 0.0024 |
Schistosoma mansoni | zinc finger protein | 0.0032 | 0.007 | 0.007 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 15263 nM | In vitro binding property against kappa opioid receptor | ChEMBL. | No reference |
Activity (binding) | = 33480 nM | In vitro binding property against mu opioid receptor | ChEMBL. | No reference |
ED50 (functional) | > 81 mg kg-1 | Antagonistic effect on mouse phenylquinone writhing (PQW ) test, subcutaneous administration | ChEMBL. | No reference |
ED50 (functional) | > 81 mg kg-1 | Antagonistic effect on mouse phenylquinone writhing (PQW ) test, peroral administration | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.