Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.012 | 0.5024 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0027 | 0.1011 | 0.0972 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0014 | 0.0458 | 0.0757 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0024 | 0.0897 | 0.2213 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0027 | 0.1011 | 0.0972 |
Schistosoma mansoni | thyroid hormone receptor | 0.0099 | 0.4138 | 0.4113 |
Brugia malayi | Choline O-acetyltransferase | 0.0099 | 0.4134 | 0.8198 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0012 | 0.0362 | 0.5813 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Schistosoma mansoni | thyroid hormone receptor | 0.0099 | 0.4138 | 0.4113 |
Echinococcus granulosus | choline O acetyltransferase | 0.0099 | 0.4134 | 0.4109 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0072 | 0.2966 | 0.2936 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0027 | 0.1011 | 0.0972 |
Trichomonas vaginalis | set domain proteins, putative | 0.0136 | 0.5739 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0013 | 0.0391 | 0.035 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0027 | 0.1011 | 0.0972 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.004 | 0.1583 | 0.303 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0458 | 0.0752 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0027 | 0.1011 | 0.0972 |
Echinococcus granulosus | FTZ F1 alpha | 0.0027 | 0.1011 | 0.0972 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.001 | 0.025 | 0.2122 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.048 | 0.0797 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0027 | 0.1011 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Schistosoma mansoni | endonuclease related | 0.0011 | 0.0324 | 0.0282 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0014 | 0.0458 | 0.0417 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0008 | 0.0198 | 0.5442 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0027 | 0.1011 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0596 | 0.0555 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0027 | 0.1011 | 0.1876 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0019 | 0.0646 | 0.1139 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0015 | 0.048 | 0.0439 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0391 | 0.0623 |
Brugia malayi | Choline O-acetyltransferase | 0.0099 | 0.4134 | 0.8198 |
Echinococcus granulosus | Endonuclease G | 0.0011 | 0.0324 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0198 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0015 | 0.048 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0027 | 0.1011 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0458 | 0.0752 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0024 | 0.0859 | 1 |
Schistosoma mansoni | 23-cyclic-nucleotide 2-phosphodiesterase | 0.0088 | 0.3642 | 0.3615 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0022 | 0.0809 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0016 | 0.0519 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.4134 | 0.8197 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0013 | 0.0391 | 0.035 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0099 | 0.4134 | 0.4109 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0015 | 0.048 | 0.0439 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0015 | 0.048 | 0.0802 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0027 | 0.1011 | 0.1158 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0013 | 0.0391 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0027 | 0.1011 | 0.1158 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0027 | 0.1011 | 0.0972 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0013 | 0.0391 | 0.035 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0099 | 0.4138 | 0.4113 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0013 | 0.0391 | 0.0623 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Trypanosoma brucei | endonuclease G, putative | 0.0011 | 0.0324 | 0.3076 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0016 | 0.0519 | 0.0479 |
Brugia malayi | nuclear receptor RXR | 0.0014 | 0.0458 | 0.0757 |
Loa Loa (eye worm) | DR-78 | 0.0013 | 0.0391 | 0.0618 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0027 | 0.1011 | 0.1872 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0083 | 0.3439 | 0.3411 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0008 | 0.0198 | 0.0156 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0015 | 0.048 | 0.0802 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.1011 | 0.0972 |
Onchocerca volvulus | 0.004 | 0.1583 | 0.2228 | |
Brugia malayi | polk-prov protein | 0.0018 | 0.0611 | 0.1067 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0083 | 0.3439 | 0.3411 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0695 | 0.7878 |
Onchocerca volvulus | 0.0027 | 0.1011 | 0.1158 | |
Onchocerca volvulus | 0.0015 | 0.048 | 0.0166 | |
Schistosoma mansoni | nuclear receptor | 0.0013 | 0.0391 | 0.035 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0024 | 0.0897 | 0.0858 |
Onchocerca volvulus | 0.0019 | 0.0646 | 0.0477 | |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0027 | 0.1011 | 0.0972 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.1011 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0008 | 0.0198 | 0.0156 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0017 | 0.0553 | 0.0512 |
Echinococcus multilocularis | ectonucleotide | 0.0016 | 0.0519 | 0.0479 |
Brugia malayi | CXXC zinc finger family protein | 0.0016 | 0.0552 | 0.0948 |
Schistosoma mansoni | hypothetical protein | 0.0235 | 1 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0024 | 0.0897 | 0.2213 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0027 | 0.1011 | 0.1876 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Schistosoma mansoni | cpg binding protein | 0.0017 | 0.0593 | 0.0552 |
Schistosoma mansoni | DNA polymerase eta | 0.0008 | 0.0198 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Brugia malayi | ecdysteroid receptor | 0.0027 | 0.1011 | 0.1876 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0011 | 0.0324 | 0.1906 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0027 | 0.1011 | 0.1876 |
Brugia malayi | steroid hormone receptor | 0.0027 | 0.1011 | 0.1876 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0013 | 0.0391 | 0.0623 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0008 | 0.0198 | 0.0232 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0036 | 0.1379 | 0.1342 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0391 | 0.035 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.001 | 0.025 | 0.2122 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0695 | 0.7878 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.001 | 0.025 | 0.2122 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.004 | 0.1583 | 0.3034 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0008 | 0.0198 | 0.1445 |
Echinococcus multilocularis | Endonuclease G | 0.0011 | 0.0324 | 0.0282 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0024 | 0.0859 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0611 | 0.1062 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0015 | 0.048 | 1 |
Brugia malayi | ecdysone receptor | 0.0013 | 0.0391 | 0.0623 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.1123 | 0.1085 |
Leishmania major | endonuclease G, putative | 0.0011 | 0.0324 | 0.4465 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Schistosoma mansoni | choline o-acyltransferase | 0.0099 | 0.4134 | 0.4109 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0024 | 0.0897 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.0596 | 0.0555 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0027 | 0.1011 | 0.0972 |
Brugia malayi | nuclear receptor NHR-67 | 0.0013 | 0.0391 | 0.0623 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0017 | 0.0596 | 0.1036 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0013 | 0.0391 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0646 | 0.1134 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0646 | 0.1134 |
Brugia malayi | tailless protein | 0.0013 | 0.0391 | 0.0623 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.1011 | 0.0972 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0015 | 0.048 | 0.0797 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Brugia malayi | conserved hypotetical protein | 0.0013 | 0.0391 | 0.0623 |
Onchocerca volvulus | 0.0019 | 0.0646 | 0.0477 | |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0013 | 0.0391 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Brugia malayi | nuclear hormone receptor | 0.0013 | 0.0391 | 0.0623 |
Toxoplasma gondii | 5'-nucleotidase, C-terminal domain-containing protein | 0.0088 | 0.3653 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0013 | 0.0391 | 0.035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0596 | 0.0555 |
Treponema pallidum | 5'-nucleotidase (ushA) | 0.0088 | 0.3653 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0027 | 0.1011 | 0.0972 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0013 | 0.0391 | 0.035 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0027 | 0.1011 | 0.1872 |
Trypanosoma cruzi | endonuclease G, putative | 0.0011 | 0.0324 | 0.1906 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0027 | 0.1011 | 0.1876 |
Leishmania major | DNA polymerase kappa, putative | 0.0012 | 0.0362 | 0.5813 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0027 | 0.1011 | 0.0972 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0027 | 0.1011 | 0.1876 |
Brugia malayi | nuclear receptor NHR-88 | 0.0013 | 0.0391 | 0.0623 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0013 | 0.0391 | 0.0618 |
Brugia malayi | nuclear receptor RXR | 0.0013 | 0.0391 | 0.0623 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0027 | 0.1011 | 0.1872 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0013 | 0.0391 | 0.035 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0027 | 0.1011 | 0.0972 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0008 | 0.0198 | 0.0156 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.1011 | 0.0972 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0611 | 0.6789 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0014 | 0.0458 | 0.0417 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0391 | 0.0623 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0024 | 0.0897 | 0.1564 |
Echinococcus granulosus | dna polymerase kappa | 0.0024 | 0.0859 | 0.0819 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0027 | 0.1011 | 0.0972 |
Toxoplasma gondii | 5'-nucleotidase, C-terminal domain-containing protein | 0.0036 | 0.1409 | 0.3658 |
Schistosoma mansoni | 23-cyclic-nucleotide 2-phosphodiesterase | 0.0088 | 0.3653 | 0.3626 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0027 | 0.1011 | 0.1872 |
Schistosoma mansoni | coup transcription factor | 0.0027 | 0.1011 | 0.0972 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0016 | 0.0552 | 0.0943 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0027 | 0.1011 | 0.0972 |
Onchocerca volvulus | 0.0016 | 0.0552 | 0.03 | |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0014 | 0.0458 | 0.0417 |
Onchocerca volvulus | 0.0017 | 0.0596 | 0.0382 | |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0072 | 0.2966 | 0.2936 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0024 | 0.0859 | 0.1496 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0027 | 0.1011 | 0.1876 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0458 | 0.0752 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0013 | 0.0391 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0458 | 0.0752 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0015 | 0.048 | 0.4268 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0017 | 0.0596 | 0.0555 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0391 | 0.035 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0027 | 0.1011 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0015 | 0.048 | 0.0802 |
Brugia malayi | Pre-SET motif family protein | 0.012 | 0.5024 | 1 |
Onchocerca volvulus | 0.0136 | 0.5739 | 1 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0014 | 0.0458 | 0.0757 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0596 | 0.0555 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0611 | 0.6789 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0458 | 0.0752 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.0362 | 0.3568 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0027 | 0.1011 | 0.0972 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0013 | 0.0391 | 0.0623 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0015 | 0.048 | 0.4268 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0013 | 0.0391 | 0.035 |
Echinococcus granulosus | dna polymerase eta | 0.0008 | 0.0198 | 0.0156 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0027 | 0.1011 | 0.0972 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0013 | 0.0391 | 0.0618 |
Loa Loa (eye worm) | acetyltransferase | 0.0083 | 0.3439 | 0.679 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0013 | 0.0391 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0646 | 0.1134 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0024 | 0.0859 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0027 | 0.1011 | 0.1876 |
Schistosoma mansoni | zinc finger protein | 0.0013 | 0.0391 | 0.035 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0024 | 0.0859 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0015 | 0.048 | 0.5097 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0006 | 0.0086 | 0.0044 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0017 | 0.0596 | 0.0555 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0006 | 0.0086 | 0.0044 |
Onchocerca volvulus | 0.0015 | 0.048 | 0.0166 | |
Trypanosoma cruzi | endonuclease G, putative | 0.0011 | 0.0324 | 0.1906 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0015 | 0.048 | 0.5097 |
Echinococcus granulosus | ectonucleotide | 0.0016 | 0.0519 | 0.0479 |
Onchocerca volvulus | 0.0015 | 0.048 | 0.0166 | |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0519 | 0.0877 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0008 | 0.0198 | 0.0156 |
Onchocerca volvulus | 0.0015 | 0.048 | 0.0166 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.0596 | 0.0555 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0014 | 0.0458 | 0.0752 |
Brugia malayi | nuclear receptor NHR-88 | 0.0027 | 0.1011 | 0.1876 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0027 | 0.1011 | 0.1876 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0027 | 0.1011 | 0.0972 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0391 | 0.0618 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0013 | 0.0391 | 0.035 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0022 | 0.0809 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0008 | 0.0198 | 0.0232 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.2966 | 0.2936 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0012 | 0.0362 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0027 | 0.1011 | 0.1872 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0027 | 0.1011 | 0.1872 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0027 | 0.1011 | 0.0972 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0027 | 0.1011 | 0.1876 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0014 | 0.0458 | 0.0417 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0015 | 0.048 | 0.4268 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0081 | 0.3338 | 0.331 |
Brugia malayi | nuclear hormone receptor | 0.0027 | 0.1011 | 0.1876 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0099 | 0.4134 | 0.8197 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0015 | 0.048 | 0.5097 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0015 | 0.048 | 0.5097 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0013 | 0.0391 | 0.0623 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0013 | 0.0391 | 0.035 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0024 | 0.0897 | 0.1564 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1011 | 0.1872 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0015 | 0.048 | 0.0797 |
Echinococcus multilocularis | dna polymerase kappa | 0.0024 | 0.0859 | 0.0819 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0022 | 0.0809 | 0.4317 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0027 | 0.1011 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0596 | 0.1031 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0027 | 0.1011 | 0.1872 |
Schistosoma mansoni | nuclear receptor | 0.0013 | 0.0391 | 0.035 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0458 | 0.0757 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0458 | 0.0757 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Giardia lamblia | Hypothetical protein | 0.0036 | 0.1398 | 1 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0015 | 0.048 | 1 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.0011 | 0.0324 | 0.0486 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0011 | 0.0324 | 0.0593 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0083 | 0.3439 | 0.6792 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0013 | 0.0391 | 0.0618 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0015 | 0.048 | 0.0439 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0015 | 0.048 | 0.5097 |
Schistosoma mansoni | cpg binding protein | 0.0016 | 0.0552 | 0.0511 |
Echinococcus multilocularis | cpg binding protein | 0.0017 | 0.0593 | 0.0552 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0017 | 0.0593 | 0.0552 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0015 | 0.048 | 0.4268 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0027 | 0.1011 | 0.1158 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0011 | 0.0324 | 0.4465 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.1583 | 0.1547 |
Trypanosoma brucei | endonuclease G, putative | 0.0011 | 0.0324 | 0.3076 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0008 | 0.0198 | 0.0226 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0015 | 0.048 | 0.0439 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0015 | 0.048 | 0.4268 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0013 | 0.0391 | 0.0623 |
Trypanosoma brucei | endonuclease G, putative | 0.0011 | 0.0324 | 0.3076 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0027 | 0.1011 | 0.1876 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0011 | 0.0324 | 0.1906 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0027 | 0.1011 | 0.0972 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.1011 | 0.0972 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0027 | 0.1011 | 0.0972 |
Schistosoma mansoni | cpg binding protein | 0.0017 | 0.0593 | 0.0552 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0015 | 0.048 | 0.4268 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0027 | 0.1011 | 0.0972 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0024 | 0.0859 | 0.1496 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0235 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0027 | 0.1011 | 0.1872 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0013 | 0.0391 | 0.035 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0034 | 0.1306 | 0.3367 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0015 | 0.048 | 0.4268 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0019 | 0.0646 | 0.0606 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0027 | 0.1011 | 0.1876 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0017 | 0.0596 | 0.1361 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.0859 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0013 | 0.0391 | 0.035 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0008 | 0.0198 | 0.0156 |
Schistosoma mansoni | choline o-acyltransferase | 0.0015 | 0.048 | 0.0439 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0027 | 0.1011 | 0.1876 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | 0 uM | In vitro inhibition of inducible vascular cell adhesion molecule-1 (VCAM-1) expression in Human aortic endothelial cells (HAEC); NE denotes no effect | ChEMBL. | 12639572 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.