Detailed information for compound 280887

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 660.808 | Formula: C29H40N8O6S2
  • H donors: 3 H acceptors: 7 LogP: 0.32 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N[C@H](C(=O)c1nccs1)CCCNC(=N)N)CN1CCN([C@@H](C1=O)CC(=O)N1CCCCC1)S(=O)(=O)Cc1ccccc1
  • InChi: 1S/C29H40N8O6S2/c30-29(31)33-11-7-10-22(26(40)27-32-12-17-44-27)34-24(38)19-36-15-16-37(45(42,43)20-21-8-3-1-4-9-21)23(28(36)41)18-25(39)35-13-5-2-6-14-35/h1,3-4,8-9,12,17,22-23H,2,5-7,10-11,13-16,18-20H2,(H,34,38)(H4,30,31,33)/t22-,23+/m0/s1
  • InChiKey: BMORWMVRWCHRDH-XZOQPEGZSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References
Homo sapiens coagulation factor II (thrombin) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi G-protein coupled receptor 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Echinococcus multilocularis neuropeptide Y receptor 0.026 0.068 0.091
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0124 0.0288 0.0385
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.034 0.091 0.3594
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0055 0.0087 0.0117
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0801 0.224 0.2995
Mycobacterium ulcerans DNA gyrase subunit A 0.0031 0.0021 0.0039
Echinococcus granulosus g protein coupled receptor 0.026 0.068 0.091
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.008 0.0161 0.0215
Schistosoma mansoni opsin-like receptor 0.026 0.068 0.091
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0107 0.0143
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.034 0.091 0.144
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0072 0.0137 0.0215
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Brugia malayi G protein-coupled receptor F59B2.13 0.026 0.068 0.1078
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0047 0.0066 0.0105
Schistosoma mansoni lamin 0.0158 0.0385 0.0515
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0058
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0138 0.0328 0.0325
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0058 0.0097 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0006 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0058 0.0054
Schistosoma mansoni hypothetical protein 0.007 0.0133 0.0178
Echinococcus granulosus tyrosine protein kinase Fyn 0.0076 0.0149 0.02
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0087 0.0182 0.0178
Brugia malayi Cyclic-nucleotide gated cation channel 0.0074 0.0142 0.0225
Trichomonas vaginalis aldehyde oxidase, putative 0.0752 0.21 0.4195
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0031 0.0021 0.0028
Echinococcus granulosus centrosomal protein of 41 kDa 0.007 0.0133 0.0178
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0064 0.0114 0.011
Brugia malayi hypothetical protein 0.0101 0.0222 0.0352
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0047 0.0066 0.0088
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0162 0.0398 0.0631
Loa Loa (eye worm) hypothetical protein 0.1004 0.2827 0.4478
Brugia malayi Inositol-1 0.0077 0.0151 0.024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.008 0.0161 0.0215
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0026 0.0006 0.0022
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0073 0.0141 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0142 0.0276
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.0058 0.0092
Leishmania major hypothetical protein, unknown function 0.0026 0.0006 0.0006
Trichomonas vaginalis disulfide oxidoreductase, putative 0.034 0.091 0.1813
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0009 0.0012
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0074 0.0143 0.0226
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0072 0.0137 0.0361
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0067 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Plasmodium vivax DNA gyrase subunit A, putative 0.0031 0.0021 0.0027
Onchocerca volvulus Alhambra homolog 0.0027 0.0009 0.0018
Schistosoma mansoni hypothetical protein 0.0046 0.0064 0.0086
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0032 0.0022 0.003
Brugia malayi hypothetical protein 0.0101 0.0221 0.0349
Echinococcus multilocularis microtubule associated protein 2 0.2617 0.7479 1
Schistosoma mansoni zinc finger protein 0.0025 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.2011 0.5731 0.7663
Leishmania major cytochrome p450-like protein 0.0096 0.0207 0.0207
Echinococcus multilocularis 0.0072 0.0137 0.0183
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0072 0.0137 0.0215
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.0009 0.0014
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0026 0.0006 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2679 0.7658 0.7657
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0055 0.0087 0.0345
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0349
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0072 0.0137 0.0361
Brugia malayi Serotonin receptor 0.026 0.068 0.1078
Onchocerca volvulus 0.0593 0.1641 0.328
Brugia malayi SRC-1 0.0076 0.0149 0.0237
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0054 0.0072
Loa Loa (eye worm) SRC-1 0.0076 0.0149 0.0237
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0074 0.0142 0.019
Echinococcus granulosus thyrotropin releasing hormone receptor 0.026 0.068 0.091
Onchocerca volvulus 0.026 0.068 0.136
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.3004 0.8597 0.8597
Echinococcus granulosus neuropeptide Y receptor 0.026 0.068 0.091
Brugia malayi G-protein coupled receptor 0.026 0.068 0.1078
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.034 0.091 0.1436
Giardia lamblia NADH oxidase lateral transfer candidate 0.128 0.3622 1
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0047 0.0066 0.0105
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.034 0.091 0.2208
Loa Loa (eye worm) hypothetical protein 0.0155 0.0377 0.0597
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.034 0.091 0.1436
Echinococcus granulosus cGMP dependent protein kinase 1 0.0028 0.0011 0.0015
Schistosoma mansoni coup transcription factor 0.0058 0.0097 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus granulosus intermediate filament protein 0.0158 0.0385 0.0515
Plasmodium vivax amine transporter, putative 0.0101 0.0221 0.0343
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0066 0.0088
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0211
Brugia malayi N-terminal motif family protein 0.0288 0.0761 0.1206
Brugia malayi larval opioid receptor 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0058 0.0097 0.0154
Schistosoma mansoni steroid hormone receptor ad4bp 0.0058 0.0097 0.013
Trypanosoma brucei hypothetical protein, conserved 0.034 0.091 0.0906
Loa Loa (eye worm) hypothetical protein 0.0593 0.1641 0.26
Brugia malayi Augmenter of liver regeneration 0.0032 0.0023 0.0036
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.0009 0.0012
Echinococcus granulosus allatostatin A receptor 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0211
Leishmania major calmodulin, putative 0.0026 0.0004 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0097 0.0154
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0099 0.0217 0.029
Leishmania major hypothetical protein, conserved 0.007 0.0133 0.0133
Echinococcus granulosus mitogen activated protein kinase 0.0141 0.0337 0.045
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0031 0.0021 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Brugia malayi RIKEN cDNA 4930451A13 0.007 0.0133 0.0211
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0066 0.0088
Trichomonas vaginalis ap endonuclease, putative 0.0045 0.0061 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.005 0.0092
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0224 0.0577 0.0909
Echinococcus granulosus calmodulin 0.0026 0.0004 0.0005
Giardia lamblia DNA repair protein RAD52 0.0718 0.2002 0.5524
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0066 0.0088
Echinococcus granulosus g protein coupled receptor 0.026 0.068 0.091
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0058 0.0097 0.013
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0066 0.0088
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0135 0.0181
Trichomonas vaginalis disulfide oxidoreductase, putative 0.034 0.091 0.1813
Loa Loa (eye worm) hypothetical protein 0.0166 0.0408 0.0646
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0026 0.0006 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0097 0.0209 0.0411
Schistosoma mansoni sodium/chloride dependent transporter 0.0593 0.1641 0.2194
Brugia malayi Protein kinase domain containing protein 0.0026 0.0006 0.001
Echinococcus multilocularis tyrosine kinase 0.0029 0.0015 0.002
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0026 0.0006 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0124 0.0288 0.0568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0142 0.0276
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0087 0.0182 0.0182
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.007 0.0133 0.0205
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Brugia malayi Bromodomain containing protein 0.0029 0.0015 0.0024
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0177 0.0441 0.0693
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0072 0.0137 0.0361
Brugia malayi ORL1-like opioid receptor 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni tyrosine kinase 0.0333 0.089 0.119
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0026 0.0006 0.0009
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0254 0.0663 0.1816
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0073 0.0141 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.034 0.091 0.144
Entamoeba histolytica rodhanase-like domain containing protein 0.007 0.0133 0.0526
Plasmodium falciparum cGMP-dependent protein kinase 0.0028 0.0011 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.034 0.091 0.091
Trichomonas vaginalis phosphofructokinase, putative 0.0097 0.0209 0.0411
Loa Loa (eye worm) hypothetical protein 0.0593 0.1641 0.26
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Trypanosoma brucei ABC transporter, putative 0.003 0.0016 0.0012
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0099 0.0215 0.0429
Onchocerca volvulus 0.0029 0.0013 0.0026
Echinococcus granulosus fmrfamide receptor 0.026 0.068 0.091
Schistosoma mansoni opsin-like receptor 0.026 0.068 0.091
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.034 0.091 0.247
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0029
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0066 0.0088
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0058 0.0097 0.013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0011 0.0015
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0101 0.0221 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0124 0.0288 0.0568
Loa Loa (eye worm) hypothetical protein 0.0162 0.0397 0.0629
Schistosoma mansoni ubiquitin-activating enzyme E1 0.007 0.0133 0.0178
Loa Loa (eye worm) phosphatidylinositol 3 0.0042 0.005 0.0079
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.034 0.091 0.1436
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0077 0.0151 0.0363
Schistosoma mansoni retinoic acid receptor RXR 0.0058 0.0097 0.013
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0026 0.0006 0.0009
Schistosoma mansoni tyrosine kinase 0.0208 0.0531 0.071
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.007 0.0133 0.0178
Loa Loa (eye worm) latrophilin receptor protein 2 0.0129 0.0304 0.0481
Schistosoma mansoni tyrosine kinase 0.0029 0.0015 0.002
Schistosoma mansoni 6-phosphofructokinase 0.0097 0.0209 0.028
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.0129 0.0172
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0066 0.0088
Onchocerca volvulus 0.026 0.068 0.136
Loa Loa (eye worm) hypothetical protein 0.0158 0.0385 0.061
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0074 0.0142 0.019
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0096 0.0207 0.0554
Onchocerca volvulus 0.0902 0.2532 0.506
Mycobacterium leprae Conserved hypothetical protein 0.007 0.0133 0.031
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0026 0.0006 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Chlamydia trachomatis DNA gyrase subunit B 0.0067 0.0124 0.0328
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0106
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.034 0.091 0.1442
Mycobacterium tuberculosis Conserved protein 0.0026 0.0006 0.0008
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0031 0.0021 0.0027
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0129 0.0304 0.0481
Schistosoma mansoni tyrosine kinase 0.0076 0.0149 0.02
Leishmania major hypothetical protein, conserved 0.007 0.0133 0.0133
Onchocerca volvulus Protein ultraspiracle homolog 0.0058 0.0097 0.0195
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0045 0.0061 0.0057
Echinococcus multilocularis PHD finger protein rhinoceros 0.0027 0.0009 0.0012
Trypanosoma cruzi NADH dehydrogenase, putative 0.034 0.091 0.091
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0072 0.0137 0.0215
Schistosoma mansoni voltage-gated potassium channel 0.0214 0.0546 0.073
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Brugia malayi nuclear hormone receptor 0.0058 0.0097 0.0154
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Loa Loa (eye worm) apoptosis regulator protein 0.0074 0.0143 0.0226
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0054 0.0085
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.026 0.068 0.091
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0072 0.0137 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Giardia lamblia Rab geranylgeranyltransferase 0.0336 0.0901 0.2479
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0097 0.013
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0047 0.0064 0.0129
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0042 0.005 0.0067
Echinococcus granulosus tm gpcr rhodopsin 0.2549 0.7282 0.9737
Trichomonas vaginalis cdc25c, putative 0.0902 0.2532 0.5058
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0072 0.0137 0.0215
Schistosoma mansoni voltage-gated potassium channel 0.0088 0.0184 0.0246
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0006
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0072 0.0137 0.0361
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0009 0.0012
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0145 0.0348 0.0466
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0066 0.0088
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0031 0.0021 0.0033
Brugia malayi 6-phosphofructokinase 0.0097 0.0209 0.0332
Echinococcus granulosus glutamate receptor 2 0.0121 0.0279 0.0373
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Giardia lamblia DNA topoisomerase II 0.0138 0.0329 0.09
Echinococcus granulosus calmodulin 0.0026 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0902 0.2532 0.4011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0238
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0498 0.1368 0.3766
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.007 0.0133 0.0259
Echinococcus multilocularis g-protein coupled receptor 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Brugia malayi glutathione reductase 0.2212 0.6312 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0076 0.0149 0.02
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0162 0.0398 0.0631
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0141 0.0337 0.0337
Schistosoma mansoni hypothetical protein 0.026 0.068 0.091
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0047 0.0066 0.0132
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0149 0.036 0.072
Treponema pallidum quinoline 2-oxidoreductase 0.0119 0.0275 0.0744
Loa Loa (eye worm) hypothetical protein 0.0336 0.0901 0.1427
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0032 0.0023 0.0019
Echinococcus multilocularis neuropeptide Y receptor 0.026 0.068 0.091
Schistosoma mansoni hypothetical protein 0.0122 0.0282 0.0377
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0333 0.089 0.119
Trichomonas vaginalis ap endonuclease, putative 0.0045 0.0061 0.0115
Echinococcus multilocularis dro:myosuppressin receptor 0.026 0.068 0.091
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Echinococcus multilocularis orexin receptor type 2 0.026 0.068 0.091
Echinococcus multilocularis tyrosine protein kinase HCK 0.0062 0.0108 0.0144
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0162 0.0398 0.1573
Plasmodium falciparum kinesin-5 0.0039 0.0042 0.0061
Loa Loa (eye worm) RGC/RGC protein kinase 0.0033 0.0025 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0838 0.2347 0.3138
Echinococcus multilocularis lamin dm0 0.0158 0.0385 0.0515
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0199 0.0505 0.0675
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0076 0.0149 0.02
Brugia malayi exodeoxyribonuclease III family protein 0.0045 0.0061 0.0097
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0097 0.0209 0.0206
Loa Loa (eye worm) hypothetical protein 0.0088 0.0184 0.0291
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0245 0.0637 0.0852
Schistosoma mansoni transient receptor potential channel 0.0047 0.0066 0.0088
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0047 0.0066 0.0105
Schistosoma mansoni ap endonuclease 0.0045 0.0061 0.0082
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Echinococcus granulosus tachykinin peptides receptor 99D 0.026 0.068 0.091
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.034 0.091 0.091
Loa Loa (eye worm) hypothetical protein 0.0055 0.0087 0.0139
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni hypothetical protein 0.1476 0.4188 0.56
Leishmania major NADH dehydrogenase, putative 0.034 0.091 0.091
Schistosoma mansoni voltage-gated potassium channel 0.0074 0.0142 0.019
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0055 0.0087 0.0117
Plasmodium vivax 6-phosphofructokinase, putative 0.0026 0.0006 0.0003
Onchocerca volvulus 0.007 0.0133 0.0266
Schistosoma mansoni thyroid hormone receptor 0.0058 0.0097 0.013
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni kinesin eg-5 0.0039 0.0042 0.0057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0213 0.0545 0.0728
Loa Loa (eye worm) RGC/RGC protein kinase 0.0033 0.0025 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0055 0.0087 0.0117
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0343
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0031 0.0021 0.0034
Echinococcus multilocularis conserved hypothetical protein 0.0047 0.0066 0.0088
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0097 0.0209 0.0564
Leishmania major hypothetical protein, unknown function 0.007 0.0133 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.0235 0.0463
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0032 0.0023 0.0031
Entamoeba histolytica hypothetical protein, conserved 0.007 0.0133 0.0526
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0047 0.0066 0.0088
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.0012
Brugia malayi M-phase phosphoprotein, mpp8 0.0101 0.0221 0.035
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0026 0.0006 0.0009
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0087 0.0182 0.0282
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0229 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Echinococcus multilocularis RUN 0.0122 0.0282 0.0377
Trichomonas vaginalis helicase, putative 0.0032 0.0022 0.0037
Toxoplasma gondii NADPH-glutathione reductase 0.128 0.3622 0.5735
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Schistosoma mansoni hypothetical protein 0.007 0.0133 0.0178
Toxoplasma gondii histone lysine methyltransferase SET1 0.0278 0.0731 0.1153
Brugia malayi tailless protein 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.028 0.0737 0.1168
Brugia malayi hypothetical protein 0.0122 0.0282 0.0447
Schistosoma mansoni hypothetical protein 0.0074 0.0143 0.0191
Leishmania major hypothetical protein, conserved 0.007 0.0133 0.0133
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0031 0.0021 0.0027
Brugia malayi hypothetical protein 0.0047 0.0066 0.0105
Schistosoma mansoni neuropeptide receptor 0.026 0.068 0.091
Toxoplasma gondii phosphofructokinase PFKII 0.0026 0.0006 0.0003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0164 0.0403 0.0799
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0074 0.0142 0.019
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0085 0.0176 0.0272
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0058 0.0097 0.0154
Schistosoma mansoni chromobox protein 0.0075 0.0148 0.0198
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.003 0.0016 0.0016
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0336 0.0901 0.1204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0336 0.0901 0.1794
Echinococcus multilocularis heat shock protein 67b2 0.007 0.0133 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0058 0.0097 0.0154
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0069 0.0128 0.0298
Onchocerca volvulus 0.0902 0.2532 0.506
Schistosoma mansoni tyrosine kinase 0.0029 0.0015 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0011 0.0015
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.0058 0.0078
Trichomonas vaginalis mercuric reductase, putative 0.128 0.3622 0.7237
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.034 0.091 0.2499
Echinococcus granulosus voltage gated potassium channel 0.0088 0.0184 0.0246
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0106 0.0235 0.0235
Mycobacterium ulcerans endonuclease IV 0.0177 0.0441 0.1202
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.026 0.068 0.1078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0144 0.028
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0047 0.0066 0.0066
Entamoeba histolytica rodhanase-like domain containing protein 0.007 0.0133 0.0526
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Loa Loa (eye worm) 6-phosphofructokinase 0.0097 0.0209 0.0332
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.034 0.091 0.2505
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0076 0.0149 0.02
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0076 0.0149 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0337 0.0666
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0058 0.0097 0.013
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0288 0.0761 0.1521
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.034 0.091 0.2499
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0072 0.0137 0.0361
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0162 0.0398 0.0533
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0097 0.0154
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0097 0.013
Trypanosoma cruzi ATP-binding cassette protein, putative 0.003 0.0016 0.0016
Brugia malayi GnHR receptor homolog 0.026 0.068 0.1078
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.128 0.3622 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0058 0.0097 0.0195
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.026 0.068 0.1078
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.026 0.068 0.1078
Echinococcus multilocularis insulin receptor 0.0333 0.089 0.119
Loa Loa (eye worm) serotonin transporter b 0.0593 0.1641 0.26
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0505 0.1386 0.3372
Brugia malayi CXXC zinc finger family protein 0.0141 0.0337 0.0535
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.007 0.0133 0.0209
Echinococcus granulosus geminin 0.1476 0.4188 0.56
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0029
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0043 0.0055 0.0073
Echinococcus granulosus voltage dependent calcium channel 0.0145 0.0348 0.0466
Schistosoma mansoni myosin xvIII 0.026 0.068 0.091
Echinococcus multilocularis isocitrate dehydrogenase 0.0099 0.0217 0.029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0026 0.0044
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0047 0.0066 0.0088
Echinococcus multilocularis Smad4 0.0033 0.0024 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0133 0.0259
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0047 0.0066 0.0088
Echinococcus granulosus thioredoxin glutathione reductase 0.2212 0.6312 0.8439
Loa Loa (eye worm) transcription factor SMAD2 0.0478 0.131 0.2076
Echinococcus multilocularis calmodulin 0.0026 0.0004 0.0005
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.0009 0.0014
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0162 0.0398 0.0533
Plasmodium falciparum thioredoxin reductase 0.2212 0.6312 1
Plasmodium vivax DNA topoisomerase II, putative 0.0146 0.0351 0.0551
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0045 0.0061 0.0082
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0162 0.0398 0.0398
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Toxoplasma gondii 6-phosphofructokinase 0.0026 0.0006 0.0003
Brugia malayi nuclear receptor NHR-88 0.0027 0.0009 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0082 0.0157
Schistosoma mansoni hypothetical protein 0.0205 0.0521 0.0696
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.034 0.091 0.247
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0019 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0058 0.0097 0.013
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0149 0.036 0.0571
Brugia malayi Cytochrome P450 family protein 0.0072 0.0137 0.0217
Schistosoma mansoni biogenic amine (5HT) receptor 0.1357 0.3844 0.5139
Loa Loa (eye worm) hypothetical protein 0.0838 0.2347 0.3719
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0145 0.0348 0.0466
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.003 0.0016 0.0025
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0358 0.0963 0.2646
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0026 0.0006 0.0003
Loa Loa (eye worm) AGC/PKG protein kinase 0.0028 0.0011 0.0018
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0032 0.0023 0.003
Plasmodium falciparum LCCL domain-containing protein 0.0122 0.0282 0.0441
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0018 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0133 0.0259
Schistosoma mansoni cpg binding protein 0.0151 0.0366 0.0489
Brugia malayi intermediate filament protein 0.0158 0.0385 0.061
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0052 0.008 0.0106
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0045 0.0061 0.0061
Mycobacterium ulcerans molybdopterin biosynthesis-like protein MoeZ 0.007 0.0133 0.0351
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0055 0.0087 0.0087
Echinococcus granulosus potassium large conductance calcium activated 0.0047 0.0066 0.0088
Leishmania major DNA polymerase eta, putative 0.0044 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0002
Echinococcus multilocularis somatostatin receptor 0.026 0.068 0.091
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.0229 0.0357
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0026 0.0006 0.0006
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0336 0.0901 0.1427
Onchocerca volvulus 0.026 0.068 0.136
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0072 0.0137 0.0215
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.128 0.3622 0.5735
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0337 0.045
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.0058 0.0058
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0752 0.21 0.4195
Onchocerca volvulus 0.0101 0.0221 0.0441
Plasmodium vivax ferrodoxin reductase, putative 0.034 0.091 0.1436
Echinococcus multilocularis survival motor neuron protein 1 0.1004 0.2827 0.3779
Giardia lamblia Rho GAP, putative 0.0063 0.0112 0.0299
Brugia malayi bZIP transcription factor family protein 0.0166 0.041 0.065
Schistosoma mansoni survival motor neuron protein 0.0205 0.0521 0.0696
Mycobacterium tuberculosis Probable oxidoreductase 0.1445 0.4097 0.6491
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.026 0.068 0.091
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0066 0.0088
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0076 0.0149 0.02
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.094 0.2642 0.4185
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.034 0.091 0.1813
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0101 0.0221 0.0295
Loa Loa (eye worm) hypothetical protein 0.0838 0.2347 0.3719
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0066 0.0088
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0085 0.0174 0.0276
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0058
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0032 0.0023 0.0023
Onchocerca volvulus 0.0027 0.0009 0.0018
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.026 0.068 0.1078
Loa Loa (eye worm) TK protein kinase 0.0069 0.0129 0.0204
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0074 0.0142 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0065 0.0122
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0058 0.0143
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.007 0.0133 0.031
Echinococcus multilocularis ATP binding cassette sub family G 0.003 0.0016 0.0021
Brugia malayi sulfakinin receptor protein 0.026 0.068 0.1078
Echinococcus multilocularis centrosomal protein of 41 kDa 0.007 0.0133 0.0178
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0087 0.0182 0.0718
Onchocerca volvulus 0.0122 0.0282 0.0564
Loa Loa (eye worm) hypothetical protein 0.0129 0.0304 0.0481
Brugia malayi hypothetical protein 0.0027 0.0009 0.0014
Plasmodium falciparum thioredoxin reductase 0.128 0.3622 0.5735
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0018 0.0014
Echinococcus granulosus heat shock protein 67b2 0.007 0.0133 0.0178
Brugia malayi Cytochrome P450 family protein 0.0096 0.0207 0.0327
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni transient receptor potential channel 0.0047 0.0066 0.0088
Echinococcus multilocularis lysine specific demethylase 5A 0.0033 0.0025 0.0034
Entamoeba histolytica hypothetical protein 0.0113 0.0255 0.1009
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0042 0.005 0.0124
Loa Loa (eye worm) hypothetical protein 0.0044 0.0058 0.0092
Brugia malayi Serotonin receptor 0.1532 0.4348 0.6889
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0337 0.0666
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0074 0.0142 0.019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0041 0.0074
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.026 0.068 0.091
Brugia malayi neuropeptide F receptor 0.026 0.068 0.1078
Brugia malayi Tachykinin-like peptides receptor 99D 0.026 0.068 0.1078
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0072 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Echinococcus multilocularis sodium and chloride dependent glycine 0.0101 0.0221 0.0295
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0026 0.0006 0.0002
Plasmodium falciparum ABC transporter G family member 2 0.003 0.0016 0.0019
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.007 0.0133 0.0178
Echinococcus granulosus dna polymerase kappa 0.0044 0.0058 0.0078
Echinococcus multilocularis alpha 1A adrenergic receptor 0.026 0.068 0.091
Schistosoma mansoni glutamate receptor AMPA 0.017 0.042 0.0562
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1445 0.4097 0.6491
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.007 0.0133 0.0211
Brugia malayi phosphofructokinase 0.0097 0.0209 0.0332
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2679 0.7658 0.7658
Echinococcus granulosus dro:myosuppressin receptor 0.026 0.068 0.091
Schistosoma mansoni tyrosine kinase 0.0333 0.089 0.119
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) 0.007 0.0133 0.0209
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0145 0.0348 0.0466
Loa Loa (eye worm) G-protein coupled receptor 0.026 0.068 0.1078
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0027 0.0009 0.0012
Plasmodium vivax glutathione reductase, putative 0.2212 0.6312 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0107 0.0143
Echinococcus multilocularis voltage dependent calcium channel 0.0145 0.0348 0.0466
Echinococcus granulosus neuropeptides capa receptor 0.026 0.068 0.091
Leishmania major hypothetical protein, conserved 0.0032 0.0023 0.0023
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0024 0.0032
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1545 0.4388 0.6952
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0099 0.0217 0.0217
Brugia malayi MH2 domain containing protein 0.0478 0.131 0.2076
Trichomonas vaginalis set domain proteins, putative 0.1758 0.5002 1
Echinococcus multilocularis lamin 0.0158 0.0385 0.0515
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0058 0.0097 0.013
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0358 0.0963 0.1524
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0733 0.2044 0.8074
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.003 0.0016 0.0025
Entamoeba histolytica calmodulin, putative 0.0026 0.0004 0.0015
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.0009 0.0012
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0066 0.0088
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0069 0.0129 0.0172
Echinococcus granulosus Ankyrin repeat domain containing protein 0.008 0.0161 0.0215
Schistosoma mansoni neuropeptide F-like receptor 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.1061 0.2991 0.474
Echinococcus multilocularis fmrfamide receptor 0.026 0.068 0.091
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1142 0.2276
Schistosoma mansoni tyrosine kinase 0.0214 0.0546 0.073
Loa Loa (eye worm) TOPoisomerase family member 0.0146 0.0351 0.0556
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0088 0.0184 0.0291
Brugia malayi Kinesin motor domain containing protein 0.0039 0.0042 0.0067
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0902 0.2532 0.5058
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0099 0.0217 0.029
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0074 0.0142 0.019
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.026 0.068 0.091
Brugia malayi Thioredoxin reductase 0.2212 0.6312 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0505 0.1386 0.2194
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0087 0.0182 0.0243
Loa Loa (eye worm) calcium channel 0.0145 0.0348 0.0552
Trypanosoma cruzi calmodulin 0.0026 0.0004 0.0004
Treponema pallidum sodium- and chloride- dependent transporter 0.0593 0.1641 0.4523
Trypanosoma cruzi Flagellar Member 6 0.0026 0.0006 0.0006
Echinococcus multilocularis voltage gated potassium channel 0.0088 0.0184 0.0246
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0058 0.0097 0.013
Echinococcus granulosus two pore calcium channel protein 2 0.0047 0.0066 0.0088
Mycobacterium ulcerans hypothetical protein 0.007 0.0133 0.0351
Echinococcus granulosus sodium and chloride dependent glycine 0.0101 0.0221 0.0295
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.007 0.0133 0.0129
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0066 0.0088
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0026 0.0006 0.0004
Loa Loa (eye worm) phosphatidylinositol 3 0.0124 0.0288 0.0456
Echinococcus granulosus cytochrome P450 2K1 0.0072 0.0137 0.0183
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0146 0.0351 0.047
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.0009 0.0012
Loa Loa (eye worm) doublecortin family protein 0.0122 0.0282 0.0447
Schistosoma mansoni ATP-binding cassette transporter 0.017 0.0422 0.0564
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0047 0.0066 0.0105
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Echinococcus granulosus neuropeptide FF receptor 2 0.026 0.068 0.091
Toxoplasma gondii thioredoxin reductase 0.2212 0.6312 1
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0752 0.21 0.4195
Loa Loa (eye worm) voltage-gated calcium channel 0.0047 0.0066 0.0105
Schistosoma mansoni hypothetical protein 0.0074 0.0143 0.0191
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0505 0.1386 0.2194
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3004 0.8597 0.8596
Brugia malayi Pre-SET motif family protein 0.0224 0.0577 0.0914
Entamoeba histolytica hypothetical protein 0.007 0.0133 0.0526
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0031 0.0021 0.0021
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0066 0.0088
Leishmania major hypothetical protein, conserved 0.034 0.091 0.091
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.0133 0.0209
Toxoplasma gondii DNA topoisomerase 2, putative 0.0146 0.0351 0.0551
Brugia malayi olfactory channel protein osm-9 0.0047 0.0067 0.0106
Schistosoma mansoni growth hormone secretagogue receptor 0.026 0.068 0.091
Loa Loa (eye worm) MH2 domain-containing protein 0.0478 0.131 0.2076
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0355 0.0953 0.1509
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.034 0.091 0.2499
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0148 0.0288
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0047 0.0066 0.0088
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0072 0.0137 0.0361
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0042 0.005 0.0122
Onchocerca volvulus 0.026 0.068 0.136
Entamoeba histolytica glutamate synthase beta subunit, putative 0.034 0.091 0.3594
Onchocerca volvulus 0.0101 0.0221 0.0442
Brugia malayi Calcitonin receptor-like protein seb-1 0.0409 0.1111 0.176
Loa Loa (eye worm) solute carrier family 6 member 4 0.0593 0.1641 0.26
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.0058 0.0229
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0052 0.008 0.0106
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0026 0.0006 0.0009
Entamoeba histolytica disulphide oxidoreductase, putative 0.034 0.091 0.3594
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0024
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0087 0.0182 0.0243
Echinococcus multilocularis short transient receptor potential channel 6 0.0047 0.0066 0.0088
Schistosoma mansoni calcium-activated potassium channel 0.0047 0.0066 0.0088
Echinococcus granulosus g-protein coupled receptor 0.026 0.068 0.091
Leishmania major hypothetical protein, conserved 0.0104 0.0229 0.0229
Echinococcus multilocularis serotonin receptor 0.0838 0.2347 0.3138
Schistosoma mansoni voltage-gated cation channel 0.0145 0.0348 0.0466
Loa Loa (eye worm) CHromoDomain protein family member 0.0031 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Echinococcus granulosus transcription factor Dp 1 0.0094 0.0201 0.0269
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.034 0.091 0.144
Schistosoma mansoni hypothetical protein 0.0026 0.0006 0.0009
Brugia malayi calmodulin 0.0026 0.0004 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0129 0.0304 0.0406
Trypanosoma brucei protein kinase A regulatory subunit 0.0026 0.0006 0.0003
Trypanosoma cruzi protein kinase A regulatory subunit 0.0026 0.0006 0.0006
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1077 0.3038 0.4062
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0343
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0074 0.0142 0.019
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0019 0.0029
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0066 0.0088
Echinococcus multilocularis cpg binding protein 0.0151 0.0366 0.0489
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0144 0.0344 0.0935
Loa Loa (eye worm) hypothetical protein 0.0073 0.0141 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0087 0.0182 0.0182
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0349
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0058 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.034 0.091 0.091
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0073 0.0141 0.0189
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0026 0.0006 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0133 0.0133
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0006 0.0004
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.003 0.0016 0.0019
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0031 0.0021 0.0027
Onchocerca volvulus 0.0026 0.0004 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0107 0.0144
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0349
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0255 0.0341
Schistosoma mansoni alpha-1 adrenergic receptor 0.026 0.068 0.091
Trypanosoma brucei trypanothione reductase 0.2212 0.6312 0.631
Loa Loa (eye worm) adenylyl cyclase 3 0.0081 0.0165 0.0261
Loa Loa (eye worm) hepatopoietin HPO2 0.0032 0.0023 0.0036
Echinococcus multilocularis serotonin transporter 0.0593 0.1641 0.2194
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0082 0.0157
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.034 0.091 0.1813
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0336 0.0901 0.1794
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.026 0.068 0.091
Echinococcus granulosus microtubule associated protein 2 0.2617 0.7479 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0053 0.0082 0.0157
Loa Loa (eye worm) hypothetical protein 0.0081 0.0165 0.0261
Brugia malayi hypothetical protein 0.0104 0.0229 0.0363
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0067 0.009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0058 0.0097 0.0154
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0073 0.0141 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Echinococcus multilocularis transfer RNA-Gly 0.0047 0.0066 0.0088
Giardia lamblia DINP protein human, muc B family 0.0044 0.0058 0.015
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0047 0.0066 0.0088
Brugia malayi MH2 domain containing protein 0.0033 0.0024 0.0038
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0146 0.0351 0.0556
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0006 0.0008
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.001
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0124 0.0288 0.0284
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0026 0.0006 0.0009
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0074 0.0142 0.019
Echinococcus granulosus tyrosine protein kinase Src64B 0.0076 0.0149 0.02
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0031 0.0019 0.0025
Echinococcus granulosus peptide allatostatin:somatostatin 0.026 0.068 0.091
Brugia malayi SET domain containing protein 0.0032 0.0023 0.0036
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0077 0.0151 0.0598
Echinococcus granulosus peregrin 0.0029 0.0015 0.002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0047 0.0066 0.0088
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0026 0.0006 0.0009
Schistosoma mansoni ABC transporter 0.0025 0.0003 0.0003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0593 0.1641 0.2194
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0009 0.0012
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.007 0.0133 0.031
Schistosoma mansoni biogenic amine receptor 0.026 0.068 0.091
Schistosoma mansoni neuropeptide receptor 0.026 0.068 0.091
Trypanosoma brucei ATP-binding cassette protein, putative 0.003 0.0016 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0072 0.0137 0.0215
Echinococcus granulosus 7tm_1 domain containing protein 0.026 0.068 0.091
Leishmania major hypothetical protein, conserved 0.007 0.0133 0.0133
Loa Loa (eye worm) ion channel NompC 0.0047 0.0066 0.0105
Brugia malayi Protein kinase domain containing protein 0.0158 0.0387 0.0613
Echinococcus multilocularis chromobox protein 1 0.0075 0.0148 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0088 0.0184 0.0246
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0336 0.0901 0.1427
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0078 0.0155 0.0207
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.034 0.091 0.1217
Echinococcus multilocularis calmodulin 0.0026 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0058 0.0097 0.0154
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0902 0.2532 0.5058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0006 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.128 0.3622 0.3622
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseB 0.007 0.0133 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0133 0.0259
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0099 0.0215 0.0215
Brugia malayi nuclear receptor RXR 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0239 0.0621 0.0984
Brugia malayi Adenylyl cyclase protein 0.0081 0.0165 0.0261
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0042 0.005 0.005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.004 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0019 0.0029
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0149 0.036 0.0482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0215 0.0422
Trichomonas vaginalis glutamate synthase, putative 0.034 0.091 0.1813
Plasmodium falciparum glutathione reductase 0.128 0.3622 0.5735
Trypanosoma brucei C-8 sterol isomerase, putative 0.1018 0.2866 0.2863
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0026 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0031 0.0021 0.0033
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0124 0.0288 0.0456
Leishmania major cytochrome p450-like protein 0.0072 0.0137 0.0137
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0151 0.0151
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.034 0.091 0.1217
Onchocerca volvulus 0.0166 0.0408 0.0815
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0902 0.2532 0.3385
Echinococcus granulosus glutamate NMDA receptor subunit 0.0343 0.0919 0.1229
Loa Loa (eye worm) hypothetical protein 0.095 0.267 0.423
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0149 0.036 0.0571
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0009 0.0014
Echinococcus granulosus neuropeptide s receptor 0.1323 0.3747 0.5011
Onchocerca volvulus 0.0902 0.2532 0.506
Onchocerca volvulus 0.026 0.068 0.136
Brugia malayi Dopamine receptor protein 2 0.026 0.068 0.1078
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0009 0.0012
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0047 0.0066 0.0105
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0254 0.0663 0.1816
Echinococcus multilocularis neuropeptide receptor 0.026 0.068 0.091
Treponema pallidum oxidoreductase 0.034 0.091 0.2501
Trypanosoma cruzi trypanothione reductase, putative 0.2212 0.6312 0.6312
Echinococcus granulosus neuropeptide receptor 0.026 0.068 0.091
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0194 0.049 0.0656
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.007 0.0133 0.0178
Trypanosoma cruzi ABC transporter, putative 0.003 0.0016 0.0016
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.034 0.091 0.2499
Mycobacterium tuberculosis Probable dehydrogenase 0.0505 0.1386 0.2194
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0072 0.0137 0.0215
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.026 0.068 0.091
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0038 0.0039 0.0081
Loa Loa (eye worm) histone methyltransferase 0.0052 0.008 0.0126
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.026 0.068 0.091
Schistosoma mansoni neuropeptide F-like receptor 0.026 0.068 0.091
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0073 0.0146
Trichomonas vaginalis glucosylceramidase, putative 0.0607 0.1682 0.3358
Brugia malayi Rhodanese-like domain containing protein 0.0902 0.2532 0.4011
Entamoeba histolytica protein kinase, putative 0.0062 0.0108 0.0426
Entamoeba histolytica hypothetical protein 0.007 0.0133 0.0526
Toxoplasma gondii hypothetical protein 0.0047 0.0066 0.0098
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0124 0.0288 0.0284
Schistosoma mansoni amine GPCR 0.026 0.068 0.091
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.128 0.3622 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.034 0.091 0.1813
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0087 0.0182 0.0182
Trypanosoma brucei protein kinase, putative 0.0141 0.0337 0.0333
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Echinococcus granulosus tyrosine kinase 0.0029 0.0015 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0024 0.0038
Echinococcus multilocularis kinesin family 1 0.03 0.0794 0.1062
Echinococcus multilocularis GPCR, family 2 0.0129 0.0304 0.0406
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0009 0.0012
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0072 0.0137 0.0361
Trichomonas vaginalis disulfide oxidoreductase, putative 0.034 0.091 0.1813
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0047 0.0066 0.0088
Echinococcus multilocularis serotonin receptor 0.0838 0.2347 0.3138
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Entamoeba histolytica hypothetical protein 0.007 0.0133 0.0526
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0031 0.0019 0.0025
Echinococcus multilocularis Polycystic kidney disease protein 0.0122 0.0282 0.0377
Onchocerca volvulus 0.0026 0.0006 0.0013
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.034 0.091 0.2499
Toxoplasma gondii hypothetical protein 0.0101 0.0221 0.0343
Brugia malayi AKH receptor 0.026 0.068 0.1078
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0145 0.0348 0.0466
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0085 0.0176 0.043
Toxoplasma gondii target of rapamycin (TOR), putative 0.0092 0.0196 0.0305
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.128 0.3622 0.3619
Brugia malayi Pre-SET motif family protein 0.1545 0.4388 0.6952
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trichomonas vaginalis cdc25b, putative 0.0902 0.2532 0.5058
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0072 0.0137 0.0215
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.034 0.091 0.247
Echinococcus granulosus jumonji domain containing protein 0.0038 0.004 0.0053
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0115 0.0261 0.0349
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0101 0.0221 0.0295
Loa Loa (eye worm) CXXC zinc finger family protein 0.0141 0.0337 0.0535
Onchocerca volvulus 0.0902 0.2532 0.506
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0099 0.0217 0.0338
Echinococcus multilocularis hyperpolarization activated cyclic 0.0074 0.0142 0.019
Echinococcus multilocularis glutamate receptor 2 0.017 0.042 0.0562
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0358 0.0963 0.2338
Mycobacterium ulcerans 6-phosphofructokinase 0.0097 0.0209 0.0561
Brugia malayi Transient-receptor-potential like protein 0.0047 0.0066 0.0105
Trypanosoma cruzi DNA topoisomerase II, putative 0.0138 0.0328 0.0328
Loa Loa (eye worm) voltage-gated potassium channel 0.0047 0.0066 0.0105
Mycobacterium ulcerans hypothetical protein 0.0122 0.0283 0.0765
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0031 0.0021 0.0031
Mycobacterium ulcerans thiosulfate sulfurtransferase SseA 0.007 0.0133 0.0351
Echinococcus multilocularis lipoxygenase domain containing protein 0.0122 0.0282 0.0377
Leishmania major hypothetical protein, conserved 0.0047 0.0066 0.0066
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0042 0.005 0.0124
Onchocerca volvulus 0.0078 0.0155 0.0309
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0031 0.0021 0.0027
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.0229 0.0225
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0133 0.0133
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0099 0.0217 0.029
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.034 0.091 0.1217
Leishmania major hypothetical protein, conserved 0.0026 0.0006 0.0006
Schistosoma mansoni nuclear receptor 0.0027 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0177 0.0441 0.0699
Echinococcus multilocularis sodium channel protein 0.0495 0.1358 0.1816
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0211
Schistosoma mansoni DNA polymerase eta 0.0044 0.0058 0.0078
Echinococcus granulosus shaker cognate 0.0047 0.0066 0.0088
Loa Loa (eye worm) hypothetical protein 0.0101 0.0222 0.0352
Loa Loa (eye worm) 6-phosphofructokinase 0.0097 0.0209 0.0332
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.128 0.3622 0.5735
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Echinococcus granulosus orexin receptor type 2 0.026 0.068 0.091
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0047 0.0066 0.0088
Schistosoma mansoni cpg binding protein 0.0141 0.0337 0.0451
Loa Loa (eye worm) phosphofructokinase 0.0097 0.0209 0.0332
Schistosoma mansoni amine GPCR 0.026 0.068 0.091
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0045 0.0061 0.0113
Brugia malayi G protein-coupled receptor 0.026 0.068 0.1078
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0229 0.0357
Mycobacterium ulcerans ferredoxin reductase 0.034 0.091 0.2499
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0045 0.0061 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.005 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0607 0.1682 0.3358
Mycobacterium tuberculosis Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) 0.007 0.0133 0.0209
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0224 0.0577 0.0772
Trichomonas vaginalis disulfide oxidoreductase, putative 0.034 0.091 0.1813
Loa Loa (eye worm) hypothetical protein 0.0025 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni glutamate receptor NMDA 0.0277 0.0728 0.0973
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0211
Brugia malayi neuropeptide F receptor 0.026 0.068 0.1078
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0124 0.0288 0.0385
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0226 0.0581 0.1161
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.007 0.0133 0.0259
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0146 0.0351 0.047
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0099 0.0217 0.029
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0055
Loa Loa (eye worm) hypothetical protein 0.0832 0.2329 0.3689
Trypanosoma cruzi cAMP response protein 1, putative 0.0026 0.0006 0.0006
Plasmodium falciparum DNA gyrase subunit B 0.0085 0.0176 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.005 0.0092
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.128 0.3622 0.5735
Brugia malayi Rhodanese-like domain containing protein 0.0902 0.2532 0.4011
Echinococcus granulosus ecdysone induced protein 78C 0.0058 0.0097 0.013
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0058 0.0143
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0097 0.013
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.128 0.3622 0.4842
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0355 0.0953 0.2619
Schistosoma mansoni glutamate receptor kainate 0.017 0.042 0.0562
Onchocerca volvulus Bile acid receptor homolog 0.0058 0.0097 0.0195
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Echinococcus granulosus serotonin receptor 0.026 0.068 0.091
Echinococcus multilocularis tyrosine protein kinase Srms 0.0069 0.0129 0.0172
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0032 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0141 0.0223
Schistosoma mansoni hypothetical protein 0.0129 0.0304 0.0406
Echinococcus granulosus cGMP dependent protein kinase 0.0028 0.0011 0.0015
Echinococcus multilocularis thyroid hormone receptor alpha 0.0058 0.0097 0.013
Giardia lamblia Hypothetical protein 0.007 0.0133 0.0358
Brugia malayi Blistered cuticle protein 3 0.0136 0.0322 0.051
Giardia lamblia Thiosulfate sulfurtransferase 0.007 0.0133 0.0358
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0087 0.0182 0.0243
Schistosoma mansoni hypothetical protein 0.0113 0.0255 0.0341
Echinococcus granulosus neuropeptide receptor 0.026 0.068 0.091
Loa Loa (eye worm) PHD-finger family protein 0.0027 0.0009 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0055 0.0087 0.0087
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0343 0.0919 0.1229
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0055 0.0087 0.0117
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0177 0.0441 0.0693
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0249 0.0649 0.1291
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0024 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0072 0.0137 0.0215
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.034 0.091 0.2499
Onchocerca volvulus 0.0158 0.0385 0.077
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0066 0.0088
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0333 0.089 0.119
Loa Loa (eye worm) hypothetical protein 0.0029 0.0013 0.002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.026 0.068 0.091
Brugia malayi nuclear receptor NHR-67 0.0027 0.0009 0.0014
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0059 0.0099 0.0095
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.034 0.091 0.1217
Trypanosoma cruzi calmodulin, putative 0.0026 0.0004 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0058 0.0097 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0087 0.0167
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.035
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0099 0.0217 0.0338
Loa Loa (eye worm) hypothetical protein 0.0046 0.0063 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Loa Loa (eye worm) thioredoxin reductase 0.2212 0.6312 1
Echinococcus multilocularis expressed conserved protein 0.0028 0.0011 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.034 0.091 0.091
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0902 0.2532 0.5058
Echinococcus multilocularis neuropeptide receptor 0.026 0.068 0.091
Schistosoma mansoni lipoxygenase 0.0445 0.1213 0.1622
Toxoplasma gondii Erv1 / Alr family protein 0.0032 0.0023 0.003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0064 0.0114 0.0152
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0076 0.0149 0.02
Echinococcus multilocularis dnaJ subfamily B 0.2011 0.5731 0.7663
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.034 0.091 0.1436
Toxoplasma gondii isocitrate dehydrogenase 0.0099 0.0217 0.0338
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0077 0.0151 0.0295
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0058 0.0097 0.013
Schistosoma mansoni hypothetical protein 0.0047 0.0066 0.0088
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0047 0.0066 0.0105
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0607 0.1682 0.2665
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0145 0.0348 0.0466
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0072 0.0137 0.0361
Entamoeba histolytica hypothetical protein 0.0204 0.052 0.2053
Trypanosoma brucei cAMP response protein 1, putative 0.0026 0.0006 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Trichomonas vaginalis glucosylceramidase, putative 0.0607 0.1682 0.3358
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0066 0.0088
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0495 0.1358 0.1816
Loa Loa (eye worm) steroid hormone receptor 0.0058 0.0097 0.0154
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1445 0.4097 1
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0085 0.0176 0.047
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.034 0.091 0.144
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0045 0.0061 0.0152
Entamoeba histolytica rodhanase-like domain containing protein 0.007 0.0133 0.0526
Schistosoma mansoni hypothetical protein 0.0261 0.0682 0.0912
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.128 0.3622 0.4842
Echinococcus granulosus PHD finger protein rhinoceros 0.0027 0.0009 0.0012
Onchocerca volvulus 0.0058 0.0097 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Echinococcus multilocularis neuropeptide receptor A26 0.1323 0.3747 0.5011
Trichomonas vaginalis thiosulfate sulfertansferase, putative 0.007 0.0133 0.0259
Mycobacterium tuberculosis Probable reductase 0.0505 0.1386 0.2194
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0072 0.0137 0.0361
Onchocerca volvulus 0.026 0.068 0.136
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0099 0.0215 0.0211
Plasmodium falciparum amino acid transporter, putative 0.0101 0.0221 0.0343
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0074 0.0143 0.0191
Schistosoma mansoni neuropeptide receptor 0.026 0.068 0.091
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.007 0.0133 0.0211
Echinococcus multilocularis epidermal growth factor receptor 0.0286 0.0754 0.1008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0112 0.0178
Echinococcus granulosus lipoxygenase domain containing protein 0.0122 0.0282 0.0377
Echinococcus granulosus transient receptor potential gamma protein 0.0047 0.0066 0.0088
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1018 0.2866 0.2866
Brugia malayi latrophilin 2 splice variant baaae 0.028 0.0737 0.1168
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.036 0.0482
Trypanosoma brucei unspecified product 0.0044 0.0058 0.0054
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Loa Loa (eye worm) hypothetical protein 0.0047 0.0064 0.0102
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Brugia malayi nuclear hormone receptor 0.0027 0.0009 0.0014
Brugia malayi nuclear receptor RXR 0.0031 0.0019 0.0029
Echinococcus multilocularis neuropeptide s receptor 0.1323 0.3747 0.5011
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0182 0.0182
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0024 0.0032
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0067 0.009
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Treponema pallidum catabolite gene activator (Crp) 0.0026 0.0006 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0058 0.0097 0.0154
Schistosoma mansoni adenoreceptor 0.026 0.068 0.091
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0011 0.0015
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0124 0.0288 0.1137
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0041 0.0074
Trypanosoma brucei cAMP binding protein, putative 0.0026 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.052 0.143 0.2266
Echinococcus granulosus sulfide:quinone oxidoreductase 0.034 0.091 0.1217
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0145 0.0348 0.0466
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0655 0.1818 0.2881
Echinococcus granulosus biogenic amine 5HT receptor 0.1357 0.3844 0.5139
Brugia malayi F/Y-rich N-terminus family protein 0.0062 0.0109 0.0172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0239 0.0621 0.083
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Brugia malayi Cytochrome P450 family protein 0.0155 0.0376 0.0595
Echinococcus multilocularis 0.0085 0.0175 0.0234
Entamoeba histolytica hypothetical protein 0.007 0.0133 0.0526
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0124 0.0288 0.0385
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.034 0.091 0.0906
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.026 0.068 0.091
Echinococcus multilocularis ecdysone induced protein 78C 0.0058 0.0097 0.013
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0058 0.0097 0.013
Plasmodium vivax kinesin-5 0.0039 0.0042 0.0061
Brugia malayi Probable DNA topoisomerase II 0.0146 0.0351 0.0556
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0239
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.034 0.091 0.0906
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0026 0.0006 0.0004
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.026 0.068 0.091
Echinococcus multilocularis calmodulin 0.0026 0.0004 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni neuropeptide receptor 0.026 0.068 0.091
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0045 0.0061 0.0082
Schistosoma mansoni glutamate synthase 0.034 0.091 0.1217
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0045 0.0061 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0082 0.0157
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0099 0.0217 0.0213
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0045 0.0061 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0058 0.0097 0.0154
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0072 0.0137 0.0361
Entamoeba histolytica hypothetical protein, conserved 0.007 0.0133 0.0526
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0028 0.0011 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.026 0.068 0.091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0308 0.0818 0.1093
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0223 0.0573 0.1569
Schistosoma mansoni intermediate filament proteins 0.0158 0.0385 0.0515
Brugia malayi putative neuropeptide receptor NPR1 0.026 0.068 0.1078
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0026 0.0006 0.001
Loa Loa (eye worm) glutamate receptor 1 0.017 0.042 0.0666
Echinococcus granulosus 7TM GPCR rhodopsin 0.026 0.068 0.091
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0141 0.0337 0.0337
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0009 0.0008
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni sodium-dependent amino acid transporter 0.0101 0.0221 0.0295
Echinococcus granulosus G protein coupled receptor 139 0.026 0.068 0.091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0239
Echinococcus granulosus cpg binding protein 0.0151 0.0366 0.0489
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.034 0.091 0.1217
Leishmania major DNA topoisomerase ii 0.0138 0.0328 0.0328
Brugia malayi Heterochromatin protein 1 0.0075 0.0148 0.0234
Echinococcus multilocularis nmda type glutamate receptor 0.0197 0.0499 0.0667
Echinococcus granulosus epidermal growth factor receptor 0.0286 0.0754 0.1008
Chlamydia trachomatis thioredoxin reductase 0.034 0.091 0.2501
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.026 0.068 0.1078
Plasmodium vivax thioredoxin reductase, putative 0.2212 0.6312 1
Echinococcus multilocularis fmrfamide receptor 0.026 0.068 0.091
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0194 0.049 0.0656
Echinococcus multilocularis allatostatin A receptor 0.026 0.068 0.091
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.034 0.091 0.1217
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0076 0.0149 0.02
Trypanosoma brucei cytochrome P450, putative 0.0096 0.0207 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0072 0.0137 0.0215
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0162 0.0398 0.0395
Toxoplasma gondii exonuclease III APE 0.0045 0.0061 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0072 0.0137 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0099 0.0215 0.0429
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0162 0.0398 0.0398
Brugia malayi hypothetical protein 0.0122 0.0282 0.0447
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.128 0.3622 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0194 0.049 0.0656
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Onchocerca volvulus 0.0033 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Echinococcus granulosus cGMP dependent protein kinase 1 0.0028 0.0011 0.0015
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0031 0.0019 0.0029
Echinococcus multilocularis calcium activated potassium channel 0.0049 0.0071 0.0095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.026 0.068 0.091
Loa Loa (eye worm) TK/ROR protein kinase 0.0026 0.0006 0.001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0058 0.0097 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Echinococcus multilocularis transient receptor potential gamma protein 0.0047 0.0066 0.0088
Echinococcus multilocularis g protein coupled receptor 0.026 0.068 0.091
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0045 0.0061 0.0242
Brugia malayi cytoplasmic intermediate filament protein 0.0085 0.0174 0.0276
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0145 0.0348 0.0466
Echinococcus multilocularis glutamate synthase 0.034 0.091 0.1217
Brugia malayi ecdysone receptor 0.0027 0.0009 0.0014
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0224 0.0577 0.0772
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Treponema pallidum catabolite gene activator 0.0026 0.0006 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0055 0.0087 0.0117
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni chromobox protein 0.0075 0.0148 0.0198
Plasmodium falciparum ferrodoxin reductase-like protein 0.034 0.091 0.1436
Loa Loa (eye worm) hypothetical protein 0.0072 0.0138 0.0219
Brugia malayi Intermediate filament tail domain containing protein 0.0158 0.0385 0.061
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0058 0.0092
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0047 0.0066 0.0088
Giardia lamblia Fructose-bisphosphate aldolase 0.0733 0.2044 0.564
Leishmania major ferric reductase, putative 0.0064 0.0114 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Loa Loa (eye worm) blistered cuticle protein 3 0.0136 0.0322 0.051
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0066 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0072 0.0137 0.0215
Schistosoma mansoni hypothetical protein 0.0135 0.032 0.0428
Echinococcus granulosus epidermal growth factor receptor 0.0214 0.0546 0.073
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Loa Loa (eye worm) melatonin receptor type 1A 0.026 0.068 0.1078
Loa Loa (eye worm) inositol-1 0.0077 0.0151 0.024
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.034 0.091 0.1436
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0129 0.0304 0.0406
Onchocerca volvulus 0.0245 0.0637 0.1274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0006 0.0003
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0336 0.0901 0.1794
Loa Loa (eye worm) hypothetical protein 0.0099 0.0215 0.0341
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0239 0.0621 0.083
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0047 0.0066 0.0105
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.026 0.068 0.1078
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0076 0.0149 0.02
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0101 0.0221 0.0595
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0337 0.0337
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0031 0.0021 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3004 0.8597 0.8597
Schistosoma mansoni 60S ribosomal protein L21 0.0062 0.0107 0.0144
Schistosoma mansoni loxhd1 0.0122 0.0282 0.0377
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0593 0.1641 0.26
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.034 0.091 0.1217
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0093 0.0147
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0072 0.0137 0.0361
Onchocerca volvulus 0.0047 0.0066 0.0132
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni glutamate receptor kainate 0.017 0.042 0.0562
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.0009 0.0014
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0026 0.0006 0.001
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0026 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0142 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.004 0.0072
Trypanosoma cruzi target of rapamycin kinase 3 0.0099 0.0215 0.0215
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0047 0.0066 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trypanosoma cruzi DNA topoisomerase II, putative 0.0138 0.0328 0.0328
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0047 0.0066 0.0105
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0033 0.0025 0.005
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.034 0.091 0.1217
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0074 0.0142 0.019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni microtubule-associated protein tau 0.2617 0.7479 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0097 0.0209 0.0209
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1018 0.2866 0.454
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.034 0.091 0.1436
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0024 0.0032
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.026 0.068 0.091
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0254 0.0663 0.1048
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0045 0.0061 0.0061
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0047 0.0066 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0058 0.0097 0.013
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0047 0.0066 0.0105
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0064 0.0086
Giardia lamblia Rab geranylgeranyltransferase 0.0087 0.0182 0.0492
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0058 0.0097 0.0154
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.034 0.091 0.1813
Brugia malayi Rhodanese-like domain containing protein 0.007 0.0133 0.0211
Trypanosoma brucei mercaptopyruvate sulfurtransferase, putative 0.007 0.0133 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0124 0.0288 0.0568
Loa Loa (eye worm) hypothetical protein 0.0104 0.0229 0.0363
Echinococcus granulosus glutamate receptor subunit protein glur 0.0073 0.0141 0.0189
Trypanosoma cruzi calmodulin 0.0026 0.0004 0.0004
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0032 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0097 0.0154
Echinococcus granulosus glutamate receptor NMDA 0.0082 0.0168 0.0224
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.034 0.091 0.1436
Trichomonas vaginalis inositol monophosphatase, putative 0.0077 0.0151 0.0295
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0047 0.0066 0.0105
Echinococcus granulosus lipoxygenase domain containing protein 0.0122 0.0282 0.0377
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0042 0.005 0.0078
Onchocerca volvulus 0.0101 0.0221 0.0441
Onchocerca volvulus 0.026 0.068 0.136
Entamoeba histolytica hypothetical protein 0.0113 0.0255 0.1009
Echinococcus granulosus mixed lineage leukemia protein mll 0.0043 0.0055 0.0073
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Plasmodium vivax DNA gyrase subunit B, putative 0.0085 0.0176 0.0272
Onchocerca volvulus Glucosylceramidase homolog 0.0399 0.108 0.2158
Loa Loa (eye worm) hypothetical protein 0.0099 0.0215 0.0341
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0505 0.1386 0.2194
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0076 0.015 0.02
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.0009 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0003
Echinococcus multilocularis jun protein 0.0166 0.041 0.0548
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0144 0.0344 0.0935
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0088 0.0184 0.0246
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni tyrosine kinase 0.0208 0.0531 0.071
Schistosoma mansoni 6-phosphofructokinase 0.0097 0.0209 0.028
Brugia malayi Guanylyl cyclase protein 23 0.0033 0.0025 0.004
Loa Loa (eye worm) hypothetical protein 0.0593 0.1641 0.26
Mycobacterium ulcerans epimerase 0.0047 0.0064 0.0161
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.0009 0.0012
Toxoplasma gondii hypothetical protein 0.0249 0.0649 0.1023
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.0009 0.0014
Schistosoma mansoni hypothetical protein 0.0048 0.0068 0.0091
Schistosoma mansoni tyrosine kinase 0.0286 0.0754 0.1008
Onchocerca volvulus 0.0026 0.0006 0.0013
Echinococcus granulosus RUN 0.0122 0.0282 0.0377
Schistosoma mansoni biogenic amine (dopamine) receptor 0.026 0.068 0.091
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0087 0.0182 0.0282
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.026 0.068 0.1078
Plasmodium falciparum glutathione reductase 0.2212 0.6312 1
Echinococcus granulosus neuropeptide receptor A26 0.1323 0.3747 0.5011
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0205 0.0521 0.0825
Echinococcus multilocularis geminin 0.1476 0.4188 0.56
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0144 0.028
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0006 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Loa Loa (eye worm) hypothetical protein 0.0145 0.0348 0.0552
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0066 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0097 0.0154
Echinococcus granulosus TRP transient receptor potential channel 0.0047 0.0066 0.0088
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.034 0.091 0.2208
Trypanosoma cruzi trypanothione reductase, putative 0.128 0.3622 0.3622
Loa Loa (eye worm) intermediate filament protein 0.0158 0.0385 0.061
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0009 0.0012
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.007 0.0133 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Brugia malayi Egg laying defective protein 4 0.0028 0.0011 0.0018
Schistosoma mansoni disulfide oxidoreductase 0.034 0.091 0.1217
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0239 0.0621 0.083
Trichomonas vaginalis chromobox protein, putative 0.005 0.0073 0.0138
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0061 0.0105 0.0141
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0066 0.0088
Echinococcus granulosus lamin dm0 0.0158 0.0385 0.0515
Echinococcus granulosus tumor protein p63 0.1132 0.3195 0.4272
Trichomonas vaginalis chromobox protein, putative 0.005 0.0073 0.0138
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0074 0.0142 0.0225
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0031 0.0021 0.0021
Schistosoma mansoni ryanodine receptor related 0.0047 0.0066 0.0088
Loa Loa (eye worm) DR-78 0.0027 0.0009 0.0014
Schistosoma mansoni biogenic amine receptor 0.026 0.068 0.091
Brugia malayi RE15519p 0.026 0.068 0.1078
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.034 0.091 0.3594
Echinococcus multilocularis neuropeptides capa receptor 0.026 0.068 0.091
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0087 0.0182 0.0288
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0024 0.0038
Schistosoma mansoni hypothetical protein 0.007 0.0133 0.0178
Echinococcus granulosus tm gpcr rhodopsin 0.026 0.068 0.091
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0047 0.0066 0.0088
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0058 0.0097 0.013
Trypanosoma brucei unspecified product 0.0031 0.0018 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0058 0.0097 0.0154
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0032 0.0023 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.0155 0.0376 0.0595
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.0058 0.0078
Brugia malayi Melatonin receptor type 1A 0.026 0.068 0.1078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0215 0.0422
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0009
Mycobacterium ulcerans monoxygenase 0.034 0.091 0.2499
Trichomonas vaginalis cdc25c, putative 0.007 0.0133 0.0259
Brugia malayi MH2 domain containing protein 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Trypanosoma brucei unspecified product 0.0031 0.0018 0.0014
Schistosoma mansoni jun-related protein 0.0135 0.032 0.0428
Echinococcus granulosus receptor type guanylyl cyclase 0.0033 0.0025 0.0033
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0031 0.0021 0.0028
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0018 0.0014
Schistosoma mansoni glutamate synthase 0.034 0.091 0.1217
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0058 0.0078
Mycobacterium tuberculosis Possible transcriptional regulatory protein (possibly ArsR-family) 0.007 0.0133 0.0209
Schistosoma mansoni opsin-like receptor 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0211
Schistosoma mansoni smad1 5 8 and 0.0033 0.0024 0.0032
Echinococcus granulosus voltage dependent calcium channel 0.0066 0.0119 0.0159
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0138 0.0328 0.0325
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0031 0.0018 0.0024
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0607 0.1682 0.2665
Onchocerca volvulus 0.0087 0.0182 0.0363
Leishmania major hypothetical protein, conserved 0.0026 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3491 1 1
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.007 0.0133 0.0205
Loa Loa (eye worm) hypothetical protein 0.0059 0.0101 0.0161
Leishmania major hypothetical protein, conserved 0.007 0.0133 0.0133
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0145 0.0348 0.0552
Loa Loa (eye worm) hypothetical protein 0.1018 0.2866 0.454
Schistosoma mansoni hypothetical protein 0.028 0.0737 0.0986
Schistosoma mansoni sulfide quinone reductase 0.034 0.091 0.1217
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0006 0.0008
Mycobacterium ulcerans NADH dehydrogenase 0.034 0.091 0.2499
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0665 0.1847 0.247
Echinococcus granulosus sodium channel protein 0.0455 0.1243 0.1662
Entamoeba histolytica ABC transporter, putative 0.003 0.0016 0.0061
Mycobacterium ulcerans dehydrogenase 0.034 0.091 0.2499
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0145 0.0348 0.0466
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Loa Loa (eye worm) TYRA-2 protein 0.026 0.068 0.1078
Loa Loa (eye worm) G-protein coupled receptor 0.026 0.068 0.1078
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.034 0.091 0.3594
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.094 0.2642 0.4185
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0082 0.0157
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3491 1 1
Echinococcus granulosus two pore calcium channel protein 1 0.0047 0.0066 0.0088
Brugia malayi Glutamate receptor 2 precursor 0.017 0.042 0.0666
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0074 0.0142 0.019
Echinococcus granulosus Rac GTPase activating protein 1 0.0073 0.0141 0.0189
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0349
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0042 0.005 0.0067
Schistosoma mansoni transient receptor potential channel 4 0.0047 0.0066 0.0088
Echinococcus granulosus tyrosine protein kinase Fyn 0.0076 0.0149 0.02
Echinococcus multilocularis transcription factor Dp 1 0.0094 0.0201 0.0269
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.0004 0.0005
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0069 0.0128 0.0201
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0009 0.0018
Plasmodium falciparum DNA gyrase subunit A 0.0031 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0902 0.2532 0.4011
Echinococcus multilocularis glutamate receptor 2 0.0121 0.0279 0.0373
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0211
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0031 0.0018 0.0024
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0072 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0029
Echinococcus granulosus biogenic amine 5HT receptor 0.0838 0.2347 0.3138
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0006 0.0003
Echinococcus granulosus ATP binding cassette sub family G 0.003 0.0016 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Echinococcus multilocularis 6 phosphofructokinase 0.0097 0.0209 0.028
Trypanosoma cruzi cytochrome P450, putative 0.0096 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0073 0.0141 0.0189
Echinococcus multilocularis receptor type guanylyl cyclase 0.0033 0.0025 0.0033
Echinococcus multilocularis Rhodanese 0.007 0.0133 0.0178
Entamoeba histolytica DNA topoisomerase II, putative 0.0146 0.0351 0.1387
Mycobacterium ulcerans glutamate synthase subunit beta 0.034 0.091 0.2499
Onchocerca volvulus 0.026 0.068 0.136
Onchocerca volvulus 0.026 0.068 0.136
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.007 0.0133 0.0129
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0026 0.0006 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0166 0.041 0.0548
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Giardia lamblia GTOR 0.0124 0.0288 0.0785
Trypanosoma cruzi cytochrome P450, putative 0.0096 0.0207 0.0207
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.007 0.0133 0.0129
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.034 0.091 0.144
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Brugia malayi glutamate synthase 0.034 0.091 0.1442
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0054 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0097 0.0209 0.0411
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0077 0.0151 0.0401
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.034 0.091 0.1442
Brugia malayi photoreceptor-specific nuclear receptor 0.0058 0.0097 0.0154
Schistosoma mansoni lamin 0.0158 0.0385 0.0515
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Brugia malayi PHD-finger family protein 0.0027 0.0009 0.0014
Giardia lamblia Hypothetical protein 0.007 0.0133 0.0358
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0074 0.0142 0.019
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0141 0.0337 0.0333
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0336 0.0901 0.3557
Echinococcus multilocularis tyrosine protein kinase Blk 0.0069 0.0129 0.0172
Onchocerca volvulus 0.026 0.068 0.136
Loa Loa (eye worm) TK/EGFR protein kinase 0.0286 0.0754 0.1194
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0064 0.0114 0.0114
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0194 0.049 0.0656
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.007 0.0133 0.0358
Entamoeba histolytica thioredoxin reductase, putative 0.034 0.091 0.3594
Schistosoma mansoni zinc finger protein 0.0027 0.0009 0.0012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0255 0.0341
Schistosoma mansoni inositol monophosphatase 0.0077 0.0151 0.0202
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0158 0.0385 0.061
Brugia malayi jmjC domain containing protein 0.0043 0.0054 0.0085
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0099 0.0217 0.0217
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0066 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0239
Loa Loa (eye worm) Smad1 0.0033 0.0024 0.0038
Loa Loa (eye worm) programmed cell death 8 0.034 0.091 0.1442
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0337 0.0337
Schistosoma mansoni amine GPCR 0.026 0.068 0.091
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0072 0.0137 0.0215
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0149 0.036 0.0482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.005 0.0092
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0665 0.1847 0.247
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0072 0.0137 0.0215
Echinococcus multilocularis sodium leak channel non selective protein 0.0047 0.0066 0.0088
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0074 0.0143 0.0191
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0052 0.0079 0.0075
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0042 0.005 0.0124
Schistosoma mansoni protein kinase 0.0033 0.0025 0.0033
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.007 0.0133 0.031
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Schistosoma mansoni dual specificity protein phosphatase 0.007 0.0133 0.0178
Echinococcus granulosus hypothetical protein 0.2167 0.6182 0.8265
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0148 0.0234
Leishmania major C-8 sterol isomerase-like protein 0.1018 0.2866 0.2866
Loa Loa (eye worm) hypothetical protein 0.0173 0.0428 0.0679
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0058 0.0097 0.013
Echinococcus multilocularis L aminoadipate semialdehyde 0.0078 0.0155 0.0207
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0066 0.0088
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0141 0.0337 0.0337
Loa Loa (eye worm) neuropeptide F receptor 0.026 0.068 0.1078
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.034 0.091 0.2499
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0072 0.0137 0.0215
Treponema pallidum hypothetical protein 0.0101 0.0221 0.0595
Echinococcus granulosus nmda type glutamate receptor 0.0197 0.0499 0.0667
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0101 0.0221 0.0295
Schistosoma mansoni cellular tumor antigen P53 0.0166 0.0408 0.0546
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.128 0.3622 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.034 0.091 0.091
Onchocerca volvulus 0.026 0.068 0.136
Toxoplasma gondii transporter, cation channel family protein 0.0047 0.0066 0.0098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0097 0.013
Entamoeba histolytica rodhanase-like domain containing protein 0.0902 0.2532 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0042 0.005 0.0079
Schistosoma mansoni Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specificprotein A14 protein) 0.007 0.0133 0.0178
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni voltage-gated ion channel 0.0047 0.0066 0.0088
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0064 0.0086
Echinococcus multilocularis sex peptide receptor 0.026 0.068 0.091
Echinococcus granulosus inositol monophosphatase 1 0.0077 0.0151 0.0202
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0047 0.0066 0.0088
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0031 0.0021 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2212 0.6312 1
Schistosoma mansoni hypothetical protein 0.026 0.068 0.091
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0255 0.0341
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0099 0.0215 0.0429
Echinococcus multilocularis calmodulin 0.0026 0.0004 0.0005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0076 0.0149 0.02
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0058 0.0097 0.0154
Brugia malayi ABC transporter family protein 0.0025 0.0003 0.0004
Echinococcus granulosus voltage gated potassium channel 0.0047 0.0066 0.0088
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.034 0.091 0.1813
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0058 0.0097 0.013
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0336 0.0901 0.1204
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0026 0.0006 0.0009
Echinococcus granulosus glutamate receptor 2 0.0194 0.049 0.0656
Brugia malayi Protein kinase domain containing protein 0.0149 0.036 0.0571
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0042 0.005 0.0067
Echinococcus multilocularis neuropeptide FF receptor 2 0.026 0.068 0.091
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.128 0.3622 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0047 0.0067 0.009
Schistosoma mansoni nuclear hormone receptor 0.0058 0.0097 0.013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1445 0.4097 0.6491
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0029 0.0045
Echinococcus granulosus short transient receptor potential channel 6 0.0047 0.0067 0.009
Echinococcus multilocularis voltage dependent calcium channel 0.0145 0.0348 0.0466
Schistosoma mansoni inositol monophosphatase 0.0077 0.0151 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0337 0.0666
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0162 0.0398 0.0398
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0087 0.0182 0.0356
Echinococcus granulosus tyrosine kinase 0.0069 0.0129 0.0172
Leishmania major hypothetical protein, unknown function 0.0047 0.0066 0.0066
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0053 0.0082 0.0157
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2549 0.7282 0.9737
Brugia malayi hypothetical protein 0.0067 0.0123 0.0195
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0229 0.0229
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0194 0.049 0.0656
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0047 0.0066 0.0088
Echinococcus granulosus smad 0.0033 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0072 0.0137 0.0215
Brugia malayi 6-phosphofructokinase 0.0097 0.0211 0.0334
Loa Loa (eye worm) hypothetical protein 0.0073 0.0141 0.0224
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0103
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0042 0.005 0.005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0088 0.0184 0.0246
Schistosoma mansoni ap endonuclease 0.0045 0.0061 0.0082
Loa Loa (eye worm) hypothetical protein 0.0153 0.0372 0.0589
Trichomonas vaginalis disulfide oxidoreductase, putative 0.034 0.091 0.1813
Echinococcus multilocularis smad 0.0033 0.0024 0.0032
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0072 0.0137 0.0361
Onchocerca volvulus 0.026 0.068 0.136
Schistosoma mansoni hypothetical protein 0.007 0.0133 0.0178
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.003 0.0015 0.0021
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0026 0.0006 0.0009
Brugia malayi PHD-finger family protein 0.003 0.0017 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0058 0.009
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0349
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0045 0.0061 0.0091
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.128 0.3622 0.4842
Echinococcus multilocularis chromobox protein 1 0.0075 0.0148 0.0198
Echinococcus granulosus nuclear factor of activated T cells 5 0.0061 0.0105 0.0141
Loa Loa (eye worm) hypothetical protein 0.0122 0.0282 0.0447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0055 0.0087 0.0084
Brugia malayi hypothetical protein 0.0113 0.0255 0.0405
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0026 0.0006 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0097 0.0154
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0072 0.0137 0.0215
Leishmania major trypanothione reductase 0.2212 0.6312 0.6312
Toxoplasma gondii rhodanese family domain-containing protein 0.007 0.0133 0.0205
Echinococcus granulosus sodium leak channel non selective protein 0.0047 0.0066 0.0088
Toxoplasma gondii hypothetical protein 0.0087 0.0182 0.0282
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0076 0.015 0.02
Plasmodium falciparum DNA topoisomerase 2 0.0146 0.0351 0.0551
Echinococcus granulosus glutamate synthase 0.034 0.091 0.1217
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0087 0.0167
Loa Loa (eye worm) TK protein kinase 0.0062 0.0108 0.0171
Echinococcus granulosus neuropeptides capa receptor 0.026 0.068 0.091
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0026 0.0005 0.0003
Echinococcus multilocularis two pore calcium channel protein 2 0.0047 0.0066 0.0088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.008 0.0108
Echinococcus multilocularis g protein coupled receptor 0.026 0.068 0.091
Schistosoma mansoni hypothetical protein 0.0129 0.0304 0.0406
Chlamydia trachomatis DNA gyrase subunit A 0.0031 0.0021 0.0042
Loa Loa (eye worm) hypothetical protein 0.0222 0.0571 0.0904
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.0229 0.0357
Loa Loa (eye worm) hypothetical protein 0.1077 0.3038 0.4813
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0133 0.0259
Echinococcus granulosus tyrosine protein kinase HCK 0.0062 0.0108 0.0144
Brugia malayi cation channel family protein 0.0047 0.0066 0.0105
Echinococcus granulosus dnaJ subfamily B 0.2011 0.5731 0.7663
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0066 0.0088
Trypanosoma brucei DNA topoisomerase ii 0.0164 0.0403 0.0399
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0024 0.0032
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.026 0.068 0.091
Echinococcus granulosus tyrosine protein kinase Fyn 0.0076 0.0149 0.02
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0072 0.0137 0.0137
Onchocerca volvulus 0.0205 0.0521 0.1041
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0064 0.0114 0.0114
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0058 0.0108
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0199 0.0505 0.08
Trypanosoma brucei hypothetical protein, conserved 0.0087 0.0182 0.0178
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0204 0.052 0.2053
Brugia malayi MoeZ/MoeB domain containing protein 0.007 0.0133 0.0211
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0011 0.0015
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0066 0.0098
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0047 0.0066 0.0105
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0145 0.0348 0.0466
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.1061 0.2991 0.474
Echinococcus granulosus 6 phosphofructokinase 0.0097 0.0209 0.028
Schistosoma mansoni hypothetical protein 0.0129 0.0304 0.0406
Schistosoma mansoni amine GPCR 0.1348 0.382 0.5108
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.007 0.0133 0.0129
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.0058 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0074 0.0143 0.0191
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0055 0.0087 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0099 0.0217 0.0342
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0009 0.0012
Loa Loa (eye worm) RGC/RGC protein kinase 0.0033 0.0025 0.004
Schistosoma mansoni hypothetical protein 0.026 0.068 0.091
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0101 0.0221 0.0295
Schistosoma mansoni amine GPCR 0.026 0.068 0.091
Echinococcus granulosus GPCR family 2 0.0129 0.0304 0.0406
Onchocerca volvulus 0.0122 0.0282 0.0564
Entamoeba histolytica hypothetical protein 0.0113 0.0255 0.1009
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0194 0.049 0.0656
Echinococcus granulosus tyrosine protein kinase Src42A 0.0064 0.0114 0.0152
Trypanosoma cruzi As/Sb Reductase, putative 0.007 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.026 0.068 0.091
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.034 0.091 0.2208
Schistosoma mansoni apoptosis regulator bax 0.0074 0.0143 0.0191
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0072 0.0137 0.0137
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0141 0.0337 0.0528
Leishmania major protein kinase, putative 0.0028 0.0011 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0031 0.0021 0.0042
Schistosoma mansoni DNA topoisomerase II 0.0146 0.0351 0.047
Leishmania major hypothetical protein, conserved 0.0026 0.0006 0.0006
Echinococcus multilocularis two pore calcium channel protein 1 0.0047 0.0066 0.0088
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0042 0.005 0.0046
Echinococcus multilocularis Rac GTPase activating protein 1 0.0073 0.0141 0.0189
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0047 0.0064 0.0161
Echinococcus multilocularis nmda type glutamate receptor 0.0107 0.0238 0.0318
Giardia lamblia Kinesin-5 0.0039 0.0042 0.0106
Echinococcus granulosus hyperpolarization activated cyclic 0.0074 0.0142 0.019
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0027 0.0008 0.001
Leishmania major DNA polymerase kappa, putative 0.0044 0.0058 0.0058
Leishmania major ATP-dependent phosphofructokinase 0.0097 0.0209 0.0209
Brugia malayi protein-tyrosine kinase 0.0069 0.0129 0.0204
Echinococcus multilocularis adenylate cyclase 9 0.0081 0.0165 0.022
Schistosoma mansoni glutamate receptor kainate 0.017 0.042 0.0562
Onchocerca volvulus 0.026 0.068 0.136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni cpg binding protein 0.0151 0.0366 0.0489
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.007 0.0133 0.0209
Loa Loa (eye worm) ABC transporter 0.0025 0.0003 0.0004
Echinococcus granulosus nmda type glutamate receptor 0.0107 0.0238 0.0318
Schistosoma mansoni calmodulin 0.0026 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.1476 0.4188 0.56
Echinococcus multilocularis ATP binding cassette sub family G 0.003 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Echinococcus multilocularis neuropeptides capa receptor 0.026 0.068 0.091
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0087 0.0182 0.0178
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.034 0.091 0.2208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0022 0.0037
Echinococcus granulosus tyrosine protein kinase Lyn 0.0078 0.0154 0.0206
Trichomonas vaginalis glutamate synthase, putative 0.034 0.091 0.1813
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0902 0.2532 0.3385
Brugia malayi Latrophilin receptor protein 2 0.0129 0.0304 0.0481
Schistosoma mansoni glutamate receptor AMPA 0.017 0.042 0.0562
Loa Loa (eye worm) TK/INSR protein kinase 0.0333 0.089 0.141
Loa Loa (eye worm) hypothetical protein 0.0288 0.0761 0.1206
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0032 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.017 0.0332
Chlamydia trachomatis endonuclease IV 0.0177 0.0441 0.1205
Treponema pallidum fructose-bisphosphate aldolase 0.0733 0.2044 0.5638
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0047 0.0066 0.0088
Echinococcus multilocularis g protein coupled receptor 0.026 0.068 0.091
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.007 0.0133 0.0313
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.003 0.0016 0.0016
Treponema pallidum hypothetical protein 0.0122 0.0283 0.0767
Brugia malayi RhoGAP domain containing protein 0.0073 0.0141 0.0223
Loa Loa (eye worm) hypothetical protein 0.0122 0.0282 0.0447
Mycobacterium ulcerans DNA gyrase subunit B 0.0085 0.0176 0.0468
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0026 0.0006 0.0009
Trypanosoma cruzi cAMP binding protein, putative 0.0026 0.0006 0.0006
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0162 0.0398 0.0533
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.034 0.091 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0005
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0047 0.0066 0.0105
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0141 0.0337 0.0337
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0718 0.2002 0.7908
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.034 0.091 0.1217
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0064 0.01
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0027 0.0009 0.0012
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0164 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.1077 0.3038 0.4813
Schistosoma mansoni biogenic amine (dopamine) receptor 0.026 0.068 0.091
Echinococcus multilocularis conserved hypothetical protein 0.1907 0.5432 0.7262
Treponema pallidum exodeoxyribonuclease (exoA) 0.0045 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Echinococcus granulosus survival motor neuron protein 1 0.1004 0.2827 0.3779
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0026 0.0006 0.0005
Plasmodium vivax multidomain scavenger receptor, putative 0.0122 0.0282 0.0441
Brugia malayi hypothetical protein 0.0031 0.0019 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0101 0.0221 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0215 0.0422
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0026 0.0006 0.0004
Echinococcus granulosus patatin phospholipase domain containing protein 0.0026 0.0006 0.0009
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.128 0.3622 0.5735
Giardia lamblia Thioredoxin reductase 0.034 0.091 0.2505
Trypanosoma brucei Flagellar Member 6 0.0026 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Entamoeba histolytica rodhanase-like domain containing protein 0.0902 0.2532 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0112 0.0177
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0072 0.0137 0.0361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.034 0.091 0.1436
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0066 0.0088
Onchocerca volvulus 0.026 0.068 0.136
Leishmania major protein kinase A regulatory subunit, putative 0.0026 0.0006 0.0006
Giardia lamblia Kinase, CMGC MAPK 0.0141 0.0337 0.0921
Treponema pallidum cyclic nucleotide binding protein 0.0026 0.0006 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0164 0.0403 0.0799
Loa Loa (eye worm) hypothetical protein 0.0074 0.0142 0.0225
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0336 0.0901 0.1422
Echinococcus granulosus lamin 0.0158 0.0385 0.0515
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0164 0.0403 0.0403
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0026 0.0006 0.0003
Mycobacterium ulcerans thiosulfate sulfurtransferase, CysA2 0.007 0.0133 0.0351
Leishmania major cyclic nucleotide-binding protein-like protein 0.0026 0.0006 0.0006
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.026 0.068 0.091
Schistosoma mansoni smad 0.0033 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.034 0.091 0.1442
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0087 0.0182 0.0288
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0058 0.0054
Toxoplasma gondii hypothetical protein 0.0047 0.0066 0.0098
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0101 0.0221 0.0295
Brugia malayi hypothetical protein 0.0031 0.0019 0.0029
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.128 0.3622 0.5735
Loa Loa (eye worm) voltage-gated potassium channel 0.0047 0.0066 0.0105
Loa Loa (eye worm) CYP4Cod1 0.0096 0.0207 0.0327
Leishmania major regulatory subunit of protein kinase a-like protein 0.0026 0.0006 0.0006
Plasmodium vivax 6-phosphofructokinase, putative 0.0026 0.0006 0.0003
Echinococcus multilocularis NMDA receptor 0.0073 0.0141 0.0189
Loa Loa (eye worm) glutamate receptor 2 0.017 0.042 0.0666
Schistosoma mansoni vesicular amine transporter 0.0047 0.0066 0.0088
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0072 0.0137 0.0361
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0026 0.0006 0.0003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0099 0.0217 0.029
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0077 0.0151 0.0234
Onchocerca volvulus 0.007 0.0133 0.0266
Echinococcus multilocularis mitogen activated protein kinase 0.0141 0.0337 0.045
Echinococcus granulosus L aminoadipate semialdehyde 0.0078 0.0155 0.0207
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Brugia malayi hypothetical protein 0.0088 0.0183 0.029
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni hypothetical protein 0.0025 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0087 0.0167
Toxoplasma gondii transporter, cation channel family protein 0.0047 0.0066 0.0098
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.0009 0.0012
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.034 0.091 0.1217
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.034 0.091 0.1217
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0028 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0409 0.1111 0.176
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0194 0.049 0.0656
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0124 0.0288 0.0288
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0026 0.0006 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0099 0.0217 0.0344
Echinococcus multilocularis mitogen activated protein kinase 3 0.0141 0.0337 0.045
Brugia malayi nuclear receptor NHR-88 0.0058 0.0097 0.0154
Giardia lamblia Glutamate synthase 0.034 0.091 0.2505
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0087 0.0182 0.0178
Echinococcus granulosus calcium activated potassium channel 0.0049 0.0071 0.0095
Toxoplasma gondii Erv1 / Alr family protein 0.0032 0.0023 0.003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0129 0.0304 0.0406
Entamoeba histolytica phosphofructokinase, putative 0.0097 0.0209 0.0827
Echinococcus multilocularis calmodulin 0.0026 0.0004 0.0005
Brugia malayi Receptor family ligand binding region containing protein 0.0033 0.0025 0.004
Plasmodium vivax rhodanese like protein, putative 0.007 0.0133 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0011 0.0015
Loa Loa (eye worm) ryanodine receptor 0.0047 0.0066 0.0105
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0194 0.049 0.0656
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0074 0.0142 0.0225
Echinococcus multilocularis dna polymerase eta 0.0044 0.0058 0.0078
Brugia malayi Dopamine receptor protein 1 0.095 0.267 0.423
Onchocerca volvulus 0.0101 0.0221 0.0441
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0151 0.0151
Echinococcus granulosus calmodulin 0.0026 0.0004 0.0005
Echinococcus multilocularis potassium large conductance calcium activated 0.0047 0.0066 0.0088
Leishmania major mitochondrial DNA topoisomerase II 0.0164 0.0403 0.0403
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0336 0.0901 0.1422
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0073 0.0141 0.0189
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0132 0.031 0.0414
Echinococcus granulosus tyrosine protein kinase Src42A 0.0076 0.0149 0.02
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0455 0.1243 0.1243
Brugia malayi Steroid receptor seven-up type 2 0.0058 0.0097 0.0154
Echinococcus granulosus kinesin family 1 0.03 0.0794 0.1062
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Onchocerca volvulus 0.0027 0.0009 0.0018
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0026 0.0006 0.0009
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0124 0.0288 0.0288
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0409 0.1111 0.176
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0229 0.0229
Onchocerca volvulus 0.026 0.068 0.136
Onchocerca volvulus Neuropeptide F receptor homolog 0.026 0.068 0.136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0082 0.0157
Loa Loa (eye worm) voltage-dependent calcium channel 0.0066 0.0119 0.0189
Schistosoma mansoni voltage-gated potassium channel 0.0214 0.0546 0.073
Chlamydia trachomatis hypothetical protein 0.007 0.0133 0.0353
Echinococcus multilocularis sodium and chloride dependent glycine 0.0101 0.0221 0.0295
Toxoplasma gondii kinesin motor domain-containing protein 0.0039 0.0042 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0238
Chlamydia trachomatis glutamine binding protein 0.0042 0.005 0.0124
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0026 0.0006 0.0008
Echinococcus granulosus somatostatin receptor 0.026 0.068 0.091
Schistosoma mansoni bromodomain containing protein 0.0064 0.0116 0.0155
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.003 0.0016 0.0021
Echinococcus multilocularis inositol monophosphatase 1 0.0077 0.0151 0.0202
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0026 0.0006 0.0005
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0006 0.0004
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0072 0.0137 0.0215
Schistosoma mansoni voltage-dependent calcium channel 0.0047 0.0066 0.0088
Echinococcus granulosus jun protein 0.0166 0.041 0.0548
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0902 0.2532 0.5058
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.068 0.091
Onchocerca volvulus 0.0141 0.0337 0.0674
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0026 0.0006 0.0008
Brugia malayi RhoGAP domain containing protein 0.0063 0.0112 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0124 0.0288 0.1137
Leishmania major hypothetical protein, conserved 0.034 0.091 0.091
Echinococcus multilocularis lipoxygenase domain containing protein 0.0122 0.0282 0.0377
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.008 0.0161 0.0215
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0081 0.0165 0.0329
Echinococcus granulosus ATP binding cassette sub family G 0.003 0.0016 0.0021
Echinococcus granulosus short transient receptor potential channel 6 0.0047 0.0066 0.0088
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.034 0.091 0.144
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0074 0.0143 0.0191
Schistosoma mansoni biogenic amine receptor 0.026 0.068 0.091
Toxoplasma gondii endonuclease IV APN 0.0177 0.0441 0.0693
Echinococcus multilocularis glutamate receptor NMDA 0.0082 0.0168 0.0224
Loa Loa (eye worm) cytochrome P450 family protein 0.0096 0.0207 0.0327
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0032 0.0022 0.003
Loa Loa (eye worm) norepinephrine transporter 0.0593 0.1641 0.26
Plasmodium falciparum phd finger protein, putative 0.0027 0.0009 0.0008
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0043 0.0055 0.0073
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0009 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0097 0.0154
Loa Loa (eye worm) glutathione reductase 0.2212 0.6312 1
Schistosoma mansoni rac gtpase activating protein 0.0073 0.0141 0.0189
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Echinococcus granulosus calmodulin 0.0026 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0097 0.0154
Treponema pallidum thioredoxin reductase (trxB) 0.034 0.091 0.2501
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.034 0.091 0.091
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0042 0.005 0.005
Leishmania major phosphatidylinositol 3-kinase, putative 0.0042 0.005 0.005
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0026 0.0006 0.0005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0101 0.0221 0.0343
Entamoeba histolytica phosphofructokinase, putative 0.0097 0.0209 0.0827
Brugia malayi Rhodanese-like domain containing protein 0.007 0.0133 0.0211
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0047 0.0064 0.0102
Onchocerca volvulus 0.1759 0.5003 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0047 0.0066 0.0088
Entamoeba histolytica hypothetical protein 0.0113 0.0255 0.1009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0733 0.2044 0.4082
Brugia malayi MAP kinase sur-1 0.0141 0.0337 0.0534
Entamoeba histolytica phosphofructokinase, putative 0.0097 0.0209 0.0827
Loa Loa (eye worm) hypothetical protein 0.0074 0.0143 0.0226
Trichomonas vaginalis Phage shock protein E precursor, putative 0.007 0.0133 0.0259
Brugia malayi Protein kinase domain containing protein 0.0333 0.089 0.141
Echinococcus granulosus sex peptide receptor 0.026 0.068 0.091
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0101 0.0221 0.0295
Echinococcus granulosus alpha 1A adrenergic receptor 0.026 0.068 0.091
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0124 0.0288 0.0288
Schistosoma mansoni tyrosine kinase 0.0076 0.0149 0.02
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0064 0.0142
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0101 0.0221 0.0295
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0099 0.0217 0.0217
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0006 0.0003
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0047 0.0066 0.0088
Echinococcus multilocularis epidermal growth factor receptor 0.0214 0.0546 0.073
Schistosoma mansoni hypothetical protein 0.026 0.068 0.091
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0072 0.0137 0.0133
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Echinococcus granulosus sodium and chloride dependent glycine 0.0101 0.0221 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0215 0.0422
Onchocerca volvulus 0.0081 0.0165 0.0329
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0149 0.036 0.0571
Trypanosoma cruzi calmodulin, putative 0.0026 0.0004 0.0004
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0129 0.0304 0.0406
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0166 0.041 0.0548
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0177 0.0441 0.1063
Echinococcus granulosus adenylate cyclase 9 0.0081 0.0165 0.022
Echinococcus multilocularis shaker cognate 0.0047 0.0066 0.0088
Echinococcus granulosus Smad4 0.0033 0.0024 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0006 0.0003
Onchocerca volvulus 0.034 0.091 0.1819
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.026 0.068 0.091
Trichomonas vaginalis glucosylceramidase, putative 0.0607 0.1682 0.3358
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0337 0.0666
Leishmania major 3-mercaptopyruvate sulfurtransferase 0.007 0.0133 0.0133
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0058 0.0092
Trichomonas vaginalis cdc25a, putative 0.007 0.0133 0.0259
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3004 0.8597 0.8597
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.026 0.068 0.091
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0144 0.0344 0.0544
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0072 0.0137 0.0361
Leishmania major hypothetical protein, conserved 0.034 0.091 0.091
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0133 0.0259
Trichomonas vaginalis DNA topoisomerase II, putative 0.0146 0.0351 0.0695
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.026 0.068 0.091
Echinococcus multilocularis calmodulin 0.0026 0.0004 0.0005
Brugia malayi Bromodomain containing protein 0.0034 0.0028 0.0045
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0076 0.0149 0.02
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0072 0.0137 0.0215
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0082 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Trichomonas vaginalis glucosylceramidase, putative 0.0607 0.1682 0.3358
Onchocerca volvulus 0.0158 0.0385 0.077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0058 0.0097 0.0154
Schistosoma mansoni smad1 5 8 and 0.0033 0.0024 0.0032
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0089 0.0188 0.0252
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0026 0.0006 0.0009
Echinococcus multilocularis ubiquitin specific protease 41 0.0055 0.0087 0.0117
Echinococcus multilocularis thioredoxin glutathione reductase 0.2212 0.6312 0.8439
Brugia malayi MH1 domain containing protein 0.0033 0.0024 0.0038
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0124 0.0288 0.0288
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.034 0.091 0.0906
Mycobacterium tuberculosis Conserved protein 0.007 0.0133 0.0209
Toxoplasma gondii cytochrome p450 superfamily protein 0.0072 0.0137 0.0211
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0073 0.0141 0.0189
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0026 0.0006 0.0009
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0101 0.0221 0.0349
Brugia malayi isocitrate dehydrogenase 0.0099 0.0217 0.0344
Mycobacterium leprae putative cytochrome p450 0.0072 0.0137 0.0319
Leishmania major hypothetical protein, conserved 0.007 0.0133 0.0133
Leishmania major cytochrome p450-like protein 0.0072 0.0137 0.0137
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Trichomonas vaginalis phosphofructokinase, putative 0.0097 0.0209 0.0411
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0027 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0208 0.0531 0.071
Giardia lamblia PHD finger protein 15 0.0027 0.0009 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0148 0.0288
Onchocerca volvulus Calmodulin homolog 0.0026 0.0004 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1142 0.2276
Brugia malayi putative neuropeptide receptor 0.026 0.068 0.1078
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.034 0.091 0.1436
Echinococcus granulosus voltage gated hydrogen channel 1 0.0047 0.0066 0.0088
Schistosoma mansoni glutamate receptor NMDA 0.0343 0.0919 0.1229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0196 0.0385
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0097 0.0209 0.033
Echinococcus multilocularis hyperpolarization activated cyclic 0.0074 0.0142 0.019
Echinococcus granulosus zinc finger protein 0.0025 0.0004 0.0005
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0066 0.0088
Schistosoma mansoni hypothetical protein 0.0072 0.0137 0.0183
Loa Loa (eye worm) hypothetical protein 0.0088 0.0183 0.029
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0031 0.0021 0.0033
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2679 0.7658 0.7658
Brugia malayi follicle stimulating hormone receptor 0.0655 0.1818 0.2881
Trypanosoma cruzi NADH dehydrogenase, putative 0.034 0.091 0.091
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0146 0.0351 0.0556
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0074 0.0142 0.019
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0072 0.0137 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.0238
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0026 0.0006 0.0003
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.0009 0.0014
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0031 0.0018 0.0024
Trypanosoma cruzi calmodulin, putative 0.0026 0.0004 0.0004
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0072 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0029
Toxoplasma gondii transporter, cation channel family protein 0.0066 0.0119 0.0183
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0055 0.0087 0.0117
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0076 0.0149 0.02
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.007 0.0133 0.0209
Onchocerca volvulus 0.0078 0.0155 0.031
Onchocerca volvulus 0.0101 0.0221 0.0442
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0043 0.0055 0.0073
Echinococcus multilocularis glutamate receptor 2 0.0194 0.049 0.0656
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trypanosoma cruzi mercaptopyruvate sulfurtransferase, putative 0.007 0.0133 0.0133
Schistosoma mansoni transient receptor potential channel 0.0047 0.0067 0.009
Brugia malayi jmjC domain containing protein 0.0089 0.0188 0.0298
Schistosoma mansoni two-pore calcium channel 0.0047 0.0066 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Echinococcus granulosus chromobox protein 1 0.0075 0.0148 0.0198
Echinococcus granulosus chromobox protein 1 0.0075 0.0148 0.0198
Onchocerca volvulus 0.026 0.068 0.136
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0031 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.026 0.068 0.091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0144 0.028
Echinococcus multilocularis FTZ F1 alpha 0.0058 0.0097 0.013
Schistosoma mansoni histamine h1 receptor 0.026 0.068 0.091
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0085 0.0176 0.0276
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0026 0.0006 0.001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.0009 0.0014
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0042 0.005 0.0046
Brugia malayi hypothetical protein 0.0027 0.0009 0.0014
Leishmania major As/Sb Reductase 0.007 0.0133 0.0133
Brugia malayi Bromodomain containing protein 0.0075 0.0146 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0162 0.0317
Entamoeba histolytica glutamate synthase beta subunit, putative 0.034 0.091 0.3594
Schistosoma mansoni hypothetical protein 0.034 0.091 0.1217
Schistosoma mansoni sulfide quinone reductase 0.034 0.091 0.1217
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0355 0.0953 0.2619
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0055 0.0087 0.0231
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.004 0.0053
Brugia malayi voltage-dependent calcium channel 0.0047 0.0066 0.0105
Onchocerca volvulus 0.0131 0.0307 0.0614
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0097 0.0209 0.0496
Brugia malayi Doublecortin family protein 0.0122 0.0282 0.0447
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.005 0.0092
Echinococcus multilocularis voltage gated potassium channel 0.0047 0.0066 0.0088
Brugia malayi Smad1 0.0033 0.0024 0.0038
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.034 0.091 0.1442
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0012 0.0016
Echinococcus granulosus ryanodine receptor 44f 0.0047 0.0066 0.0088
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.026 0.068 0.091
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0026 0.0006 0.0009
Schistosoma mansoni hypothetical protein 0.0129 0.0304 0.0406
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0199 0.0505 0.0675
Brugia malayi Glutamate receptor 1 precursor 0.017 0.042 0.0666
Schistosoma mansoni smad1 5 8 and 0.0033 0.0024 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3491 1 1
Brugia malayi Isocitrate dehydrogenase 0.0099 0.0217 0.0344
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0028 0.0011 0.0015
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0142 0.0277
Loa Loa (eye worm) hypothetical protein 0.0076 0.015 0.0237
Schistosoma mansoni neuropeptide f receptor 76f 0.026 0.068 0.091
Giardia lamblia ABC transporter 0.0029 0.0014 0.0029
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0047 0.0066 0.0088
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0058 0.0097 0.013
Brugia malayi hypothetical protein 0.1004 0.2827 0.4478
Treponema pallidum NADH oxidase 0.128 0.3622 1
Echinococcus granulosus ATP binding cassette sub family G 0.003 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0078 0.0155 0.0245
Schistosoma mansoni eyes absent homolog 0.0088 0.0183 0.0245
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.0009 0.0012
Echinococcus granulosus dna polymerase eta 0.0044 0.0058 0.0078
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0077 0.0151 0.0295
Entamoeba histolytica rodhanase-like domain containing protein 0.0902 0.2532 1
Echinococcus multilocularis musashi 0.0158 0.0385 0.0515
Entamoeba histolytica kinesin, putative 0.0039 0.0042 0.0167
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Treponema pallidum cyclic nucleotide binding protein 0.0026 0.0006 0.0002
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0072 0.0137 0.0361
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.026 0.068 0.091
Brugia malayi hypothetical protein 0.0131 0.0307 0.0486
Schistosoma mansoni lipoxygenase 0.0665 0.1847 0.247
Schistosoma mansoni cytochrome P450 0.0072 0.0137 0.0183
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.007 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0088 0.0183 0.029
Brugia malayi chromobox protein homolog 3 0.0047 0.0065 0.0103
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0009 0.0008
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0141 0.0337 0.0534
Echinococcus granulosus ubiquitin specific protease 41 0.0055 0.0087 0.0117
Trypanosoma cruzi As/Sb Reductase, putative 0.007 0.0133 0.0133
Chlamydia trachomatis DNA gyrase subunit B 0.0085 0.0176 0.047
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.034 0.091 0.091
Echinococcus multilocularis G protein coupled receptor 139 0.026 0.068 0.091
Mycobacterium ulcerans hypothetical protein 0.034 0.091 0.2499
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0087 0.0182 0.0243
Echinococcus granulosus hyperpolarization activated cyclic 0.0074 0.0142 0.019
Schistosoma mansoni rab6-interacting 0.0122 0.0282 0.0377
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.068 0.091
Schistosoma mansoni tyrosine kinase 0.0214 0.0546 0.073
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0031 0.0021 0.0034
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0902 0.2532 0.5058
Trichomonas vaginalis glucosylceramidase, putative 0.0399 0.108 0.2152
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.034 0.091 0.0906
Echinococcus granulosus neuropeptide Y receptor 0.026 0.068 0.091
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0047 0.0066 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0607 0.1682 0.3358
Brugia malayi Cytochrome P450 family protein 0.0096 0.0207 0.0327
Loa Loa (eye worm) hypothetical protein 0.0101 0.0221 0.0349
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0214 0.0546 0.073
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.003 0.0016 0.0025
Schistosoma mansoni sodium/chloride dependent transporter 0.0102 0.0225 0.0301
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0074 0.0143 0.0191
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0058
Leishmania major dihydrolipoamide dehydrogenase, putative 0.128 0.3622 0.3622
Echinococcus granulosus serotonin transporter 0.0593 0.1641 0.2194
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0058 0.0054
Brugia malayi gonadotropin-releasing hormone receptor 2 0.026 0.068 0.1078
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0066 0.0088
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1357 0.3844 0.5139
Loa Loa (eye worm) hypothetical protein 0.0058 0.0097 0.0154
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0031 0.0021 0.0017
Brugia malayi ion channel NompC 0.0047 0.0066 0.0105
Toxoplasma gondii selenide, water dikinase 0.034 0.091 0.1436
Schistosoma mansoni hypothetical protein 0.0074 0.0143 0.0191
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.034 0.091 0.091
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Plasmodium falciparum transporter, putative 0.0101 0.0221 0.0343
Echinococcus granulosus tyrosine protein kinase Blk 0.0069 0.0129 0.0172
Loa Loa (eye worm) hypothetical protein 0.0066 0.0119 0.0189
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.0058 0.0078
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0505 0.1386 0.2194
Plasmodium vivax SET domain protein, putative 0.0224 0.0577 0.0909
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0078 0.0155 0.0245
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0054 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0026 0.0006 0.0003
Onchocerca volvulus 0.026 0.068 0.136
Brugia malayi steroid hormone receptor 0.0058 0.0097 0.0154
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni nuclear receptor 0.0027 0.0009 0.0012
Mycobacterium ulcerans flavoprotein disulfide reductase 0.128 0.3622 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0096 0.0207 0.0327
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.034 0.091 0.1442
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1239 0.3504 0.4685
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0058 0.0097 0.0154
Chlamydia trachomatis DNA gyrase subunit A 0.0031 0.0021 0.0042
Leishmania major calmodulin, putative 0.0026 0.0004 0.0004
Trichomonas vaginalis Phage shock protein E precursor, putative 0.007 0.0133 0.0259
Schistosoma mansoni rab6-interacting 0.0122 0.0282 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0011 0.0015
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.128 0.3622 0.5738
Schistosoma mansoni Smad4 0.0033 0.0024 0.0032
Echinococcus multilocularis ryanodine receptor 44f 0.0047 0.0066 0.0088
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0177 0.0441 0.0697
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.026 0.068 0.091
Echinococcus granulosus tm gpcr rhodopsin 0.0801 0.224 0.2995
Loa Loa (eye worm) hypothetical protein 0.0832 0.2329 0.3689
Echinococcus granulosus histone lysine methyltransferase setb 0.0239 0.0621 0.083
Brugia malayi MH1 domain containing protein 0.0033 0.0024 0.0038
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0058 0.0108
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0099 0.0217 0.0213
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0199 0.0505 0.08
Echinococcus granulosus insulin receptor 0.0333 0.089 0.119
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0097 0.013
Brugia malayi Furin-like cysteine rich region family protein 0.0286 0.0754 0.1194
Echinococcus granulosus FTZ F1 alpha 0.0058 0.0097 0.013
Trypanosoma cruzi cAMP response protein 1 0.0026 0.0006 0.0006
Toxoplasma gondii isocitrate dehydrogenase 0.0099 0.0217 0.0338
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0733 0.2044 0.8074
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0065 0.013
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0105
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0103
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0336 0.0901 0.1204
Trypanosoma brucei NADH dehydrogenase 0.034 0.091 0.0906
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0066 0.0088
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0026 0.0006 0.0003
Brugia malayi Dopamine receptor 0.026 0.068 0.1078
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0059 0.0101 0.0161
Echinococcus multilocularis peregrin 0.0029 0.0015 0.002
Mycobacterium leprae Conserved hypothetical protein 0.0072 0.0137 0.0319
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0058 0.0097 0.013
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0409 0.1111 0.176
Schistosoma mansoni polycystin 1-related 0.0122 0.0282 0.0377
Brugia malayi CHD4 protein 0.0031 0.0018 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0065 0.0122
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0031 0.0019 0.0025
Brugia malayi ecdysteroid receptor 0.0058 0.0097 0.0154
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0026 0.0006 0.0003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0072 0.0137 0.0361
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.0009 0.0012
Plasmodium vivax ABC transporter G family member 2, putative 0.003 0.0016 0.0019
Echinococcus multilocularis tumor protein p63 0.1132 0.3195 0.4272
Brugia malayi conserved hypotetical protein 0.0027 0.0009 0.0014
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0026 0.0006 0.001
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.026 0.068 0.136
Echinococcus granulosus mitogen activated protein kinase 3 0.0141 0.0337 0.045
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0045 0.0061 0.0095
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0106 0.0235 0.0231
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0087 0.0182 0.0182
Echinococcus multilocularis ATP binding cassette sub family G 0.003 0.0016 0.0021
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0177 0.0441 0.0699
Plasmodium falciparum rhodanese like protein, putative 0.007 0.0133 0.0205
Mycobacterium ulcerans hypothetical protein 0.0047 0.0064 0.0161
Loa Loa (eye worm) kinesin-like protein KLP2 0.0039 0.0042 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2679 0.7658 0.7658
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0089 0.0188 0.0252
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0058 0.0097 0.0154
Echinococcus granulosus Polycystic kidney disease protein 0.0122 0.0282 0.0377
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0902 0.2532 0.3385
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0014
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0026 0.0006 0.0009
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1077 0.3038 0.4813
Onchocerca volvulus Dual oxidase homolog 0.0136 0.0322 0.0643
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0033 0.0058
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0072 0.0137 0.0361
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0047 0.0066 0.0132
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0045 0.0061 0.0091
Schistosoma mansoni peptide (allatostatin)-like receptor 0.026 0.068 0.091
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0099 0.0217 0.029
Trichomonas vaginalis apoptosis inducing factor, putative 0.034 0.091 0.1813
Schistosoma mansoni sodium/chloride dependent transporter 0.0101 0.0221 0.0295
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0047 0.0066 0.0088
Leishmania major protein kinase, putative 0.0028 0.0011 0.0011
Brugia malayi cytochrome P450 0.0072 0.0137 0.0217
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0026 0.0006 0.0009
Brugia malayi hypothetical protein 0.026 0.068 0.1078
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0151 0.0148
Echinococcus multilocularis G-protein coupled receptor, putative 0.026 0.068 0.091
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.026 0.068 0.091
Echinococcus granulosus Rhodanese 0.007 0.0133 0.0178
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0026 0.0006 0.0009
Echinococcus granulosus hypothetical protein 0.0047 0.0066 0.0088
Toxoplasma gondii hypothetical protein 0.0101 0.0221 0.0343
Trichomonas vaginalis cdc25b, putative 0.0902 0.2532 0.5058
Schistosoma mansoni glutamate synthase 0.034 0.091 0.1217
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0002
Echinococcus multilocularis zinc finger protein 0.0025 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0054
Brugia malayi cation channel family protein 0.0047 0.0066 0.0105
Loa Loa (eye worm) hypothetical protein 0.026 0.068 0.1078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.026 0.068 0.091
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0055 0.0087 0.0087
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.128 0.3622 0.3622
Leishmania major calmodulin, putative 0.0026 0.0004 0.0004
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.128 0.3622 0.5737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0215 0.0422
Loa Loa (eye worm) cytochrome P450 0.0072 0.0137 0.0217
Trichomonas vaginalis glutathione reductase, putative 0.128 0.3622 0.7237
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0182 0.0182

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.037 uM In vitro inhibitory activity against factor Xa ChEMBL. 12639568
IC50 (binding) = 0.037 uM In vitro inhibitory activity against factor Xa ChEMBL. 12639568
IC50 (binding) = 8 uM In vitro inhibitory activity against serine protease thrombin ChEMBL. 12639568
IC50 (binding) = 8 uM In vitro inhibitory activity against serine protease thrombin ChEMBL. 12639568

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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