Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.113928 | 1 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.113928 | 1 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.113928 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.113928 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.113928 | 1 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.0388948 | 0.197689 | 0.214249 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.037923 | 0.187298 | 0.096125 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0861968 | 0.703479 | 0.763016 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.106624 | 0.921903 | 0.913142 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.037923 | 0.187298 | 0.187298 |
Echinococcus granulosus | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0388948 | 0.197689 | 0.107682 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0388948 | 0.197689 | 0.107682 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.113928 | 1 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.5 |
Echinococcus granulosus | glutamate receptor 2 | 0.0314493 | 0.118075 | 0.118075 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.113928 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0861968 | 0.703479 | 0.5 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.106624 | 0.921903 | 0.913142 |
Loa Loa (eye worm) | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0861968 | 0.703479 | 0.763016 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.106624 | 0.921903 | 1 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Echinococcus granulosus | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Toxoplasma gondii | hypothetical protein | 0.0388948 | 0.197689 | 0.214249 |
Toxoplasma gondii | methionine aminopeptidase | 0.106624 | 0.921903 | 1 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.037923 | 0.187298 | 0.096125 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0314493 | 0.118075 | 0.118075 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.037923 | 0.187298 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.106624 | 0.921903 | 0.921886 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0861968 | 0.703479 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Echinococcus granulosus | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0388948 | 0.197689 | 0.107682 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.113928 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.113928 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0861968 | 0.703479 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus granulosus | carbonic anhydrase II | 0.113928 | 1 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0861968 | 0.703479 | 0.703479 |
Echinococcus multilocularis | carbonic anhydrase II | 0.113928 | 1 | 1 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0861968 | 0.703479 | 0.670214 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0473401 | 0.287993 | 0.287993 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0473401 | 0.287993 | 0.208116 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.106624 | 0.921903 | 0.921886 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0383197 | 0.19154 | 0.100843 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.106624 | 0.921903 | 0.921903 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0861968 | 0.703479 | 0.670214 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0314493 | 0.118075 | 0.118075 |
Leishmania major | carbonic anhydrase-like protein | 0.113928 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.106624 | 0.921903 | 0.921903 |
Toxoplasma gondii | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.763016 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0861968 | 0.703479 | 0.5 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0388948 | 0.197689 | 0.107682 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0388948 | 0.197689 | 0.107682 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0388948 | 0.197689 | 0.107682 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0861968 | 0.703479 | 0.763016 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.106624 | 0.921903 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.0388948 | 0.197689 | 0.107682 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0861968 | 0.703479 | 0.5 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0298401 | 0.100869 | 0.100869 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.037923 | 0.187298 | 0.187298 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.037923 | 0.187298 | 0.096125 |
Echinococcus multilocularis | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Loa Loa (eye worm) | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0473401 | 0.287993 | 0.287993 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0314493 | 0.118075 | 0.118075 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0861968 | 0.703479 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 | 12467620 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.