Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0861968 | 0.703479 | 0.763016 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0388948 | 0.197689 | 0.107682 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0861968 | 0.703479 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.106624 | 0.921903 | 0.921903 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.113928 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus multilocularis | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0861968 | 0.703479 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0861968 | 0.703479 | 0.703479 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0314493 | 0.118075 | 0.118075 |
Schistosoma mansoni | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.106624 | 0.921903 | 0.921886 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0298401 | 0.100869 | 0.100869 |
Loa Loa (eye worm) | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Toxoplasma gondii | hypothetical protein | 0.0388948 | 0.197689 | 0.214249 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0388948 | 0.197689 | 0.107682 |
Loa Loa (eye worm) | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0861968 | 0.703479 | 0.5 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.037923 | 0.187298 | 0.096125 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.113928 | 1 | 1 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0861968 | 0.703479 | 0.670214 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus granulosus | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0383197 | 0.19154 | 0.100843 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0388948 | 0.197689 | 0.107682 |
Loa Loa (eye worm) | hypothetical protein | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus multilocularis | carbonic anhydrase II | 0.113928 | 1 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Toxoplasma gondii | methionine aminopeptidase | 0.106624 | 0.921903 | 1 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.037923 | 0.187298 | 0.187298 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.037923 | 0.187298 | 0.5 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0314493 | 0.118075 | 0.118075 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0388948 | 0.197689 | 0.107682 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.106624 | 0.921903 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.113928 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.113928 | 1 | 1 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.037923 | 0.187298 | 0.187298 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0861968 | 0.703479 | 0.763016 |
Echinococcus granulosus | glutamate receptor 2 | 0.0314493 | 0.118075 | 0.118075 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.037923 | 0.187298 | 0.096125 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.5 |
Echinococcus granulosus | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.037923 | 0.187298 | 0.096125 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.113928 | 1 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0861968 | 0.703479 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0388948 | 0.197689 | 0.107682 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.113928 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.763016 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.106624 | 0.921903 | 0.913142 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0861968 | 0.703479 | 0.670214 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0388948 | 0.197689 | 0.107682 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.106624 | 0.921903 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.0388948 | 0.197689 | 0.214249 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0388948 | 0.197689 | 0.107682 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0314493 | 0.118075 | 0.118075 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0473401 | 0.287993 | 0.287993 |
Leishmania major | carbonic anhydrase-like protein | 0.113928 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0861968 | 0.703479 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0861968 | 0.703479 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.106624 | 0.921903 | 0.921886 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.106624 | 0.921903 | 0.921886 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0861968 | 0.703479 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0473401 | 0.287993 | 0.208116 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.106624 | 0.921903 | 0.921903 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.113928 | 1 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0861968 | 0.703479 | 0.763016 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0473401 | 0.287993 | 0.287993 |
Schistosoma mansoni | carbonic anhydrase | 0.0388948 | 0.197689 | 0.107682 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.106624 | 0.921903 | 0.913142 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.113928 | 1 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.113928 | 1 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.113928 | 1 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0388948 | 0.197689 | 0.197689 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 | 12467620 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.