Detailed information for compound 282661

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 212.226 | Formula: C8H8N2O3S
  • H donors: 2 H acceptors: 2 LogP: 0.54 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1ccc2c(c1)oc(c2)S(=O)(=O)N
  • InChi: 1S/C8H8N2O3S/c9-6-2-1-5-3-8(14(10,11)12)13-7(5)4-6/h1-4H,9H2,(H2,10,11,12)
  • InChiKey: XOQWLQCRELKNGM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0211 0.0657 0.244
Onchocerca volvulus 0.0109 0.0308 0.0662
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0337 0.1084 0.3265
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0024 0.0052
Echinococcus granulosus tyrosine protein kinase Src64B 0.0038 0.0065 0.0072
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0088 0.0235 0.0262
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0119 0.034 0.0379
Schistosoma mansoni smdr2 0.0022 0.001 0.0011
Brugia malayi hypothetical protein 0.0109 0.0309 0.0756
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0209 0.0648 0.1995
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.017
Leishmania major cathepsin L-like protease 0.0056 0.0126 0.0126
Plasmodium falciparum glutathione reductase 0.0971 0.3244 1
Onchocerca volvulus 0.0119 0.034 0.0731
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0797 0.265 1
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0022 0.0011 0.0031
Loa Loa (eye worm) thioredoxin reductase 0.0971 0.3244 0.7957
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0051 0.0124
Echinococcus multilocularis carbonic anhydrase II 0.0147 0.0438 0.0488
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Plasmodium vivax kinesin-5 0.0023 0.0014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0366 0.1184 0.2905
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2468 0.8342 0.8386
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0011
Echinococcus granulosus carbonic anhydrase 0.0034 0.0051 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.072 0.239 0.5141
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0119 0.034 0.0379
Giardia lamblia GTOR 0.0091 0.0248 0.0935
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0184 0.0563 0.0627
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Mycobacterium ulcerans DNA polymerase IV 0.0079 0.0205 0.0774
Leishmania major C-8 sterol isomerase-like protein 0.1137 0.381 0.383
Brugia malayi Melatonin receptor type 1A 0.0119 0.034 0.0834
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0248 0.0533
Loa Loa (eye worm) hypothetical protein 0.0073 0.0186 0.0456
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0041
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0057 0.0132 0.0147
Brugia malayi nuclear hormone receptor 0.0019 0.0001 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0897 0.2991 0.9008
Trichomonas vaginalis glutamate synthase, putative 0.0211 0.0657 0.1412
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.0069 0.0169
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0033 0.0049 0.012
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0585 0.193 0.4732
Leishmania major trypanothione reductase 0.0971 0.3244 0.3261
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0396 0.1284 0.1432
Echinococcus granulosus peregrin 0.006 0.014 0.0156
Brugia malayi ecdysone receptor 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0211 0.0657 0.0656
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0028 0.0032 0.0098
Loa Loa (eye worm) hypothetical protein 0.0409 0.1329 0.3259
Loa Loa (eye worm) beta-glucuronidase 0.024 0.0753 0.1847
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0971 0.3244 0.3244
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0211 0.0657 0.0732
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.03 0.0644
Entamoeba histolytica P-glycoprotein-2 0.0022 0.001 0.0027
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0089 0.0099
Echinococcus granulosus carbonic anhydrase 0.0034 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0023 0.0023
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0022 0.0011 0.0032
Brugia malayi Thioredoxin reductase 0.0971 0.3244 0.7957
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.0069 0.0077
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0051 0.0056
Brugia malayi Blistered cuticle protein 3 0.0148 0.044 0.1079
Echinococcus granulosus 7tm_1 domain containing protein 0.0119 0.034 0.0379
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0205 0.0206
Toxoplasma gondii NADPH-glutathione reductase 0.0797 0.265 0.8167
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0105 0.0225
Echinococcus granulosus biogenic amine 5HT receptor 0.0366 0.1184 0.132
Schistosoma mansoni cpg binding protein 0.0077 0.0199 0.0221
Schistosoma mansoni sulfide quinone reductase 0.0211 0.0657 0.0732
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0033 0.0049 0.0054
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0107 0.0402
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0001 0.0001
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0115 0.0246
Schistosoma mansoni nuclear receptor 0.0019 0.0001 0.0001
Trypanosoma cruzi major cysteine proteinase, putative 0.0044 0.0085 0.0086
Loa Loa (eye worm) programmed cell death 8 0.0211 0.0657 0.1611
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0065 0.0072
Onchocerca volvulus 0.0119 0.034 0.0731
Plasmodium vivax SET domain protein, putative 0.0176 0.0535 0.1649
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0626 0.207 0.2308
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.008 0.021 0.0234
Echinococcus granulosus neuropeptide receptor 0.0119 0.034 0.0379
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0001 0.0002
Brugia malayi nuclear receptor NHR-67 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0199 0.0489
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0176 0.0535 0.0597
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0047 0.0095 0.0106
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.0022 0.0011 0.0041
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0971 0.3244 0.3261
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0074 0.0082
Toxoplasma gondii melibiase subfamily protein 0.0086 0.023 0.0708
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0119 0.034 0.0379
Plasmodium falciparum heterochromatin protein 1 0.0022 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0409 0.1329 0.3259
Loa Loa (eye worm) hypothetical protein 0.0366 0.1184 0.2905
Echinococcus granulosus dro:myosuppressin receptor 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.017
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0074 0.0082
Loa Loa (eye worm) hypothetical protein 0.0078 0.0204 0.05
Onchocerca volvulus Dual oxidase homolog 0.0148 0.044 0.0946
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0011
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0407 0.0409
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0014 0.005
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0154 0.0171
Leishmania major carbonic anhydrase-like protein 0.0147 0.0438 0.044
Toxoplasma gondii hypothetical protein 0.0047 0.0097 0.0298
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0201 0.0224
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0027 0.003
Loa Loa (eye worm) inositol-1 0.0209 0.0648 0.1588
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0074 0.0181
Schistosoma mansoni DNA polymerase eta 0.0051 0.011 0.0122
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0897 0.2991 0.299
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0142 0.0349
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0023 0.0023
Echinococcus granulosus muscleblind protein 0.0144 0.0429 0.0477
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0088 0.0235 0.0262
Trichomonas vaginalis taga, putative 0.0022 0.001 0.0021
Treponema pallidum hypothetical protein 0.002 0.0004 0.0014
Schistosoma mansoni hypothetical protein 0.0136 0.0398 0.0444
Trypanosoma brucei unspecified product 0.0072 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0061 0.0146 0.0357
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0409 0.1329 0.3258
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0069 0.0149
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0049 0.0105
Schistosoma mansoni rab6-interacting 0.0077 0.0199 0.0222
Loa Loa (eye worm) CXXC zinc finger family protein 0.0077 0.0199 0.0487
Echinococcus granulosus glutamate synthase 0.0211 0.0657 0.0732
Onchocerca volvulus 0.0119 0.034 0.0731
Echinococcus multilocularis neuropeptide Y receptor 0.0119 0.034 0.0379
Plasmodium vivax thioredoxin reductase, putative 0.0971 0.3244 1
Brugia malayi putative neuropeptide receptor 0.0119 0.034 0.0834
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0119 0.034 0.0379
Trichomonas vaginalis glucosylceramidase, putative 0.072 0.239 0.5141
Schistosoma mansoni jun-related protein 0.0136 0.0398 0.0444
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0074 0.0082
Schistosoma mansoni glutamate synthase 0.0211 0.0657 0.0732
Loa Loa (eye worm) hypothetical protein 0.0033 0.0049 0.012
Schistosoma mansoni biogenic amine receptor 0.0119 0.034 0.0379
Leishmania major p-glycoprotein 0.0022 0.001 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0074 0.018
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0023 0.0023
Loa Loa (eye worm) DR-78 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0096 0.0264 0.0648
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0681 0.2256 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0074 0.0181
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0088 0.0235 0.0262
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0211 0.0657 0.2478
Schistosoma mansoni hypothetical protein 0.0062 0.0147 0.0164
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.001 0.003
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0023 0.0023
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.001 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0074 0.0181
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0011
Echinococcus multilocularis lipoxygenase domain containing protein 0.0077 0.0199 0.0222
Leishmania major cathepsin L-like protease 0.0056 0.0126 0.0126
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0012 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0053 0.0059
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0074 0.0082
Onchocerca volvulus 0.0119 0.034 0.0731
Brugia malayi hypothetical protein 0.0047 0.0098 0.0239
Toxoplasma gondii hypothetical protein 0.0022 0.0011 0.0033
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.0021
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0093 0.0104
Onchocerca volvulus 0.0127 0.037 0.0794
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0106 0.0299 0.03
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0119 0.034 0.0835
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0071 0.0079
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0119 0.034 0.0379
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0014 0.0041
Trichomonas vaginalis inositol monophosphatase, putative 0.0022 0.0011 0.0023
Echinococcus multilocularis lipoxygenase domain containing protein 0.0077 0.0199 0.0222
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0034 0.0051 0.0125
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0074 0.0082
Onchocerca volvulus Neuropeptide F receptor homolog 0.0119 0.034 0.0731
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0023 0.0085
Schistosoma mansoni intermediate filament proteins 0.0127 0.037 0.0412
Trypanosoma cruzi calmodulin 0.0026 0.0024 0.0024
Echinococcus multilocularis somatostatin receptor 0.0119 0.034 0.0379
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0075 0.0084
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0009 0.0022
Echinococcus multilocularis dro:myosuppressin receptor 0.0119 0.034 0.0379
Echinococcus granulosus g protein coupled receptor 0.0119 0.034 0.0379
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0211 0.0657 0.2023
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0033 0.0049 0.0054
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0022 0.0011 0.0023
Trypanosoma cruzi DNA repair protein, putative 0.0029 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Echinococcus multilocularis thioredoxin glutathione reductase 0.0971 0.3244 0.3617
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0106 0.0299 0.1126
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0119 0.034 0.0379
Trichomonas vaginalis glucosylceramidase, putative 0.0498 0.1633 0.3513
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0211 0.0657 0.0656
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0091 0.0248 0.0249
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0107 0.0119
Echinococcus multilocularis neuropeptides capa receptor 0.0119 0.034 0.0379
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0027
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0019 0.0002 0.0005
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.0069 0.0077
Trichomonas vaginalis DNA polymerase eta, putative 0.0079 0.0205 0.0441
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0019 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0248 0.0533
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0023 0.0026
Echinococcus granulosus hypothetical protein 0.0796 0.2647 0.2951
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0106 0.0299 0.03
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0035 0.0054 0.0166
Echinococcus granulosus sex peptide receptor 0.0119 0.034 0.0379
Trypanosoma cruzi calmodulin, putative 0.0026 0.0024 0.0024
Brugia malayi 6-phosphofructokinase 0.0107 0.0301 0.0738
Toxoplasma gondii PHD-finger domain-containing protein 0.0056 0.0128 0.0393
Echinococcus granulosus epidermal growth factor receptor 0.008 0.0208 0.0231
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0069 0.0077
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0051 0.0124
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0028 0.0032 0.0036
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0023 0.0085
Echinococcus granulosus geminin 0.0946 0.3159 0.3522
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0011
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0022 0.0011 0.0031
Echinococcus granulosus dna polymerase eta 0.0051 0.011 0.0122
Trichomonas vaginalis Heterochromatin protein, putative 0.0022 0.0012 0.0026
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0076 0.0197 0.0423
Echinococcus granulosus tachykinin peptides receptor 99D 0.0119 0.034 0.0379
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0074 0.0082
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0028 0.0032 0.0036
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0797 0.265 0.2954
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.0438 0.044
Echinococcus granulosus Polycystic kidney disease protein 0.0077 0.0199 0.0222
Brugia malayi hypothetical protein 0.0031 0.0043 0.0106
Loa Loa (eye worm) hypothetical protein 0.0162 0.0489 0.1199
Schistosoma mansoni hypothetical protein 0.0158 0.0473 0.0527
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0176 0.0535 0.0597
Plasmodium falciparum LCCL domain-containing protein 0.0077 0.0199 0.0614
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0051 0.011 0.0269
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0028 0.0032 0.0036
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0259 0.082 0.3095
Onchocerca volvulus 0.029 0.0924 0.1986
Echinococcus multilocularis neuropeptide s receptor 0.1352 0.454 0.5061
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0069 0.0077
Loa Loa (eye worm) hypothetical protein 0.0088 0.0235 0.0576
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0023 0.0085
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0211 0.0657 0.1412
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0106 0.0299 0.0642
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.0069 0.0077
Toxoplasma gondii thioredoxin reductase 0.0971 0.3244 1
Plasmodium falciparum calmodulin 0.0026 0.0024 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0074 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0105 0.0224
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0119 0.034 0.0834
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0047 0.0052
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.0021
Loa Loa (eye worm) hypothetical protein 0.0144 0.0429 0.1051
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0091 0.0248 0.0249
Schistosoma mansoni pap-inositol-14-phosphatase 0.0022 0.0011 0.0012
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0023 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0022
Leishmania major protein kinase, putative 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0023 0.0023
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1137 0.381 0.9344
Echinococcus granulosus L aminoadipate semialdehyde 0.008 0.021 0.0234
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0035 0.0054 0.0054
Echinococcus granulosus tm gpcr rhodopsin 0.0119 0.034 0.0379
Schistosoma mansoni sodium/chloride dependent transporter 0.0237 0.0745 0.083
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Onchocerca volvulus 0.0076 0.0197 0.0423
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0797 0.265 1
Brugia malayi phosphofructokinase 0.0107 0.03 0.0735
Onchocerca volvulus 0.1384 0.4649 1
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0035 0.0054 0.0223
Brugia malayi cytoplasmic intermediate filament protein 0.0068 0.0169 0.0413
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0211 0.0657 0.2023
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0033 0.0049 0.0054
Loa Loa (eye worm) twinkle helicase 0.0096 0.0264 0.0648
Loa Loa (eye worm) hypothetical protein 0.0109 0.0306 0.0751
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0012 0.0013
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.0024 0.0027
Echinococcus multilocularis tumor protein p63 0.1014 0.3391 0.3781
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0014 0.005
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0035 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0107 0.0107
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0011
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0051 0.0056
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0797 0.265 0.8167
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0106 0.0299 0.03
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0211 0.0657 0.0732
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0211 0.0657 0.2478
Brugia malayi hypothetical protein 0.0039 0.0069 0.0169
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0001 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0119 0.034 0.0379
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0107 0.0107
Onchocerca volvulus 0.0077 0.0199 0.0428
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0023 0.0026
Schistosoma mansoni neuropeptide receptor 0.0119 0.034 0.0379
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0074 0.0082
Onchocerca volvulus Alhambra homolog 0.0056 0.0128 0.0274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0211 0.0657 0.1412
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0038 0.0065 0.0072
Echinococcus granulosus tyrosine protein kinase Lyn 0.0038 0.0067 0.0074
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0086 0.0228 0.0229
Brugia malayi nuclear receptor NHR-88 0.004 0.0074 0.018
Brugia malayi nuclear hormone receptor 0.004 0.0074 0.018
Echinococcus multilocularis glutamate synthase 0.0211 0.0657 0.0732
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0028 0.0032 0.0032
Echinococcus multilocularis kinesin family 1 0.0176 0.0535 0.0596
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0074 0.0082
Echinococcus multilocularis serotonin receptor 0.0366 0.1184 0.132
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.03 0.03
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0168 0.0187
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0797 0.265 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0088
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0047 0.0052
Brugia malayi isocitrate dehydrogenase 0.0028 0.0032 0.0078
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.0226
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.001 0.0011
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0035 0.013
Entamoeba histolytica hypothetical protein 0.0031 0.0043 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0105 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0074 0.018
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0099
Trypanosoma brucei carbonic anhydrase-like protein 0.0147 0.0438 0.044
Plasmodium falciparum ataxin-2 like protein, putative 0.0073 0.0186 0.0573
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0002 0.0002
Plasmodium vivax multidomain scavenger receptor, putative 0.0077 0.0199 0.0614
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0023 0.0023
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0211 0.0657 0.2478
Echinococcus multilocularis G protein coupled receptor 139 0.0119 0.034 0.0379
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0187 0.0573 0.0573
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0797 0.265 0.2664
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0106 0.0299 0.0333
Brugia malayi bZIP transcription factor family protein 0.0167 0.0504 0.1237
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0065 0.0072
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0051 0.011 0.0122
Mycobacterium ulcerans DNA polymerase IV 0.0079 0.0205 0.0774
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0074 0.0082
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0797 0.265 0.8167
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0168 0.0508 0.0566
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0071 0.0079
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0027
Onchocerca volvulus 0.0131 0.0382 0.0822
Brugia malayi SET domain containing protein 0.003 0.004 0.0097
Loa Loa (eye worm) glutathione reductase 0.0971 0.3244 0.7957
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0022 0.0011 0.0011
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.001 0.0011
Brugia malayi M-phase phosphoprotein, mpp8 0.0109 0.0308 0.0755
Brugia malayi GnHR receptor homolog 0.0119 0.034 0.0834
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0023 0.0025
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0091 0.0248 0.1083
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0074 0.0082
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0099 0.011
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0086 0.023 0.0256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0105 0.0225
Loa Loa (eye worm) hypothetical protein 0.0034 0.0051 0.0125
Brugia malayi jmjC domain containing protein 0.0072 0.0183 0.0448
Loa Loa (eye worm) hypothetical protein 0.0109 0.0309 0.0757
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0084 0.0205
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0074
Schistosoma mansoni calmodulin 0.0026 0.0024 0.0027
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0051 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2153 0.7268 0.7306
Brugia malayi steroid hormone receptor 0.004 0.0074 0.018
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0198 0.0611 0.0681
Schistosoma mansoni amine GPCR 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.0076 0.0197 0.0483
Loa Loa (eye worm) RGS-3 protein 0.0039 0.0069 0.017
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0119 0.034 0.0379
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0023 0.0085
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0147 0.0436 0.0486
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni hypothetical protein 0.0189 0.0581 0.0648
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0051 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0072 0.0153
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0126 0.0126
Echinococcus multilocularis dnaJ subfamily B 0.1096 0.367 0.4092
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0074 0.018
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.001 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0035 0.0106
Loa Loa (eye worm) hypothetical protein 0.0785 0.2611 0.6403
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0077 0.0289
Echinococcus multilocularis neuropeptide FF receptor 2 0.0119 0.034 0.0379
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0023 0.0085
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Schistosoma mansoni amine GPCR 0.0119 0.034 0.0379
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0086 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0107 0.0107
Leishmania major cytochrome p450-like protein 0.0025 0.0023 0.0023
Treponema pallidum ATP-dependent RNA helicase 0.0026 0.0024 0.0091
Echinococcus granulosus g protein coupled receptor 0.0119 0.034 0.0379
Schistosoma mansoni hypothetical protein 0.0088 0.0235 0.0262
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0209 0.0648 0.0651
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.001 0.0011
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0028 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0069 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0119 0.034 0.0379
Onchocerca volvulus 0.0119 0.034 0.0731
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Echinococcus multilocularis g protein coupled receptor 0.0119 0.034 0.0379
Brugia malayi sulfakinin receptor protein 0.0119 0.034 0.0834
Onchocerca volvulus 0.0237 0.0745 0.1601
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0211 0.0657 0.244
Schistosoma mansoni biogenic amine (5HT) receptor 0.0119 0.034 0.0379
Brugia malayi glutathione reductase 0.0971 0.3244 0.7957
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0024
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0211 0.0657 0.1977
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0211 0.0657 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0062
Schistosoma mansoni nuclear hormone receptor 0.004 0.0074 0.0082
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0797 0.265 0.8167
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0022 0.0011 0.0041
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0035 0.0106
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0062
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus carbonic anhydrase 0.0034 0.0051 0.0056
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0039 0.0044
Schistosoma mansoni hypothetical protein 0.0119 0.034 0.0379
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0026 0.0024 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0001 0.0001
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0585 0.193 0.4732
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0184 0.0396
Toxoplasma gondii PHD-finger domain-containing protein 0.0056 0.0128 0.0393
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0012 0.0037
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0065 0.0072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0119 0.034 0.0379
Entamoeba histolytica hypothetical protein 0.0039 0.0069 0.029
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0023 0.0023
Schistosoma mansoni multidrug resistance protein 0.0022 0.001 0.0011
Echinococcus granulosus G protein coupled receptor 139 0.0119 0.034 0.0379
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0084 0.0205
Onchocerca volvulus 0.0077 0.0199 0.0428
Echinococcus granulosus cGMP dependent protein kinase 0.0019 0.0002 0.0002
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0027
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0023 0.0085
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0022 0.0011 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0065 0.0072
Brugia malayi hypothetical protein 0.0073 0.0186 0.0456
Echinococcus multilocularis Polycystic kidney disease protein 0.0077 0.0199 0.0222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Echinococcus granulosus intermediate filament protein 0.0127 0.037 0.0412
Echinococcus granulosus neuropeptide s receptor 0.1352 0.454 0.5061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Brugia malayi Cyclic-nucleotide gated cation channel 0.0033 0.0049 0.0119
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0035 0.0054 0.0166
Trypanosoma brucei unspecified product 0.0035 0.0056 0.0056
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0247 0.0777 0.1904
Echinococcus multilocularis G-protein coupled receptor, putative 0.0119 0.034 0.0379
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0211 0.0657 0.1412
Echinococcus granulosus neuropeptide Y receptor 0.0119 0.034 0.0379
Brugia malayi Pre-SET motif family protein 0.1216 0.4077 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0144 0.0426 0.0916
Schistosoma mansoni hypothetical protein 0.0088 0.0235 0.0262
Onchocerca volvulus 0.0109 0.0308 0.0662
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0074 0.018
Brugia malayi Kinesin motor domain containing protein 0.0023 0.0014 0.0034
Echinococcus granulosus lipoxygenase domain containing protein 0.0077 0.0199 0.0222
Loa Loa (eye worm) hypothetical protein 0.0189 0.0581 0.1425
Schistosoma mansoni multidrug resistance protein 0.0022 0.001 0.0011
Schistosoma mansoni rab6-interacting 0.0077 0.0199 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0299 0.0642
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.0021
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.03 0.1313
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0084 0.0084
Echinococcus granulosus serotonin receptor 0.0119 0.034 0.0379
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0033 0.0048 0.0054
Echinococcus multilocularis peregrin 0.006 0.014 0.0156
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0001 0.0002
Mycobacterium ulcerans NADH dehydrogenase 0.0211 0.0657 0.2478
Schistosoma mansoni hypothetical protein 0.0088 0.0235 0.0262
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0019 0.0002 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0176 0.0535 0.0597
Schistosoma mansoni tyrosine kinase 0.0078 0.0202 0.0224
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.0069 0.0169
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.001 0.0027
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0147 0.0436 0.0486
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0106 0.0299 0.0642
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0044 0.0094
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0119 0.034 0.0835
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0027
Leishmania major ferric reductase, putative 0.0069 0.0173 0.0173
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0071 0.0079
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.03 0.0301
Brugia malayi Inositol monophosphatase family protein 0.0022 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0027
Schistosoma mansoni thyroid hormone receptor 0.004 0.0074 0.0082
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0337 0.1084 0.4091
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.03 0.0644
Loa Loa (eye worm) hypothetical protein 0.0525 0.1724 0.4229
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0119 0.034 0.0379
Plasmodium falciparum cGMP-dependent protein kinase 0.0019 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0025
Trypanosoma cruzi calmodulin, putative 0.0026 0.0024 0.0024
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0069 0.0077
Toxoplasma gondii histone lysine methyltransferase SET1 0.0156 0.0468 0.1441
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0074
Schistosoma mansoni tyrosine kinase 0.0038 0.0065 0.0072
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0009 0.001
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0001 0.0002
Loa Loa (eye worm) melatonin receptor type 1A 0.0119 0.034 0.0835
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0211 0.0657 0.1977
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni carbonic anhydrase-related 0.0034 0.0051 0.0056
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0094 0.0257 0.0773
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0211 0.0657 0.0732
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0183 0.0449
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.0069 0.0077
Onchocerca volvulus 0.0119 0.034 0.0731
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0115 0.0246
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Echinococcus granulosus dna polymerase kappa 0.0079 0.0205 0.0229
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0069 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.0657 0.066
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0031 0.0043 0.0048
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0154 0.0171
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0074 0.0082
Giardia lamblia PHD finger protein 15 0.0056 0.0128 0.0481
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0211 0.0657 0.2023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Onchocerca volvulus 0.0127 0.037 0.0794
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0077 0.0236
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0001 0.0001
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0154 0.0378
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0074 0.0082
Entamoeba histolytica hypothetical protein 0.0194 0.0597 0.2631
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.03 0.0334
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0119 0.034 0.0379
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0028 0.0032 0.0032
Plasmodium vivax ferrodoxin reductase, putative 0.0211 0.0657 0.2023
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0041 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2153 0.7268 0.7306
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0062 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0012 0.0026
Schistosoma mansoni hypothetical protein 0.0022 0.0012 0.0013
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0074 0.0082
Brugia malayi Serotonin receptor 0.057 0.1878 0.4605
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0088 0.0235 0.0575
Onchocerca volvulus 0.0198 0.0611 0.1314
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0069 0.0077
Loa Loa (eye worm) hypothetical protein 0.0034 0.0051 0.0125
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0107 0.0107
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0126 0.0126
Onchocerca volvulus 0.004 0.0074 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0248 0.0533
Loa Loa (eye worm) cytochrome P450 0.0025 0.0023 0.0056
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Brugia malayi manba-prov protein 0.0084 0.0222 0.0544
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0033 0.0049 0.0054
Schistosoma mansoni hypothetical protein 0.0173 0.0526 0.0586
Schistosoma mansoni polycystin 1-related 0.0077 0.0199 0.0222
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.001 0.003
Entamoeba histolytica disulphide oxidoreductase, putative 0.0211 0.0657 0.2898
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0183 0.0204
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0035 0.0106
Echinococcus granulosus chromobox protein 1 0.0079 0.0207 0.023
Chlamydia trachomatis replicative DNA helicase 0.0337 0.1084 0.4091
Echinococcus granulosus serotonin transporter 0.0237 0.0745 0.083
Brugia malayi Inositol-1 0.0209 0.0648 0.1588
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0211 0.0657 0.0732
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0065 0.0072
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0209 0.0648 0.0651
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.001 0.0025
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.03 0.0301
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0091 0.0248 0.0249
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0023 0.0023
Loa Loa (eye worm) histone methyltransferase 0.003 0.0039 0.0097
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.0084 0.0084
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0119 0.034 0.0379
Echinococcus multilocularis fmrfamide receptor 0.0119 0.034 0.0379
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0211 0.0657 0.1412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0126 0.0126
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2939 0.9947 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.072 0.239 0.5862
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0205 0.0206
Leishmania major calmodulin, putative 0.0026 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0034 0.0051 0.0056
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0074 0.0082
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0023 0.0085
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Plasmodium vivax ataxin-2 like protein, putative 0.0073 0.0186 0.0573
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.03 0.0644
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0074 0.0082
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0023 0.0085
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0053 0.0059
Onchocerca volvulus 0.0119 0.034 0.0731
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0023 0.0023
Brugia malayi ecdysteroid receptor 0.004 0.0074 0.018
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0051 0.011 0.011
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.011 0.0269
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0074 0.0082
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0119 0.034 0.0379
Echinococcus multilocularis carbonic anhydrase 0.0034 0.0051 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0001 0.0001
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0069 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Plasmodium falciparum carbonic anhydrase 0.0034 0.0051 0.0156
Schistosoma mansoni loxhd1 0.0077 0.0199 0.0222
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0049 0.0054
Giardia lamblia Hypothetical protein 0.0022 0.0011 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0005
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0014 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0074 0.0181
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0211 0.0657 0.2023
Trichomonas vaginalis glucosylceramidase, putative 0.0498 0.1633 0.3513
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0001 0.0001
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.008 0.0208 0.0231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) isocitrate dehydrogenase 0.0028 0.0032 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0121 0.0259
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.0074 0.0082
Schistosoma mansoni myo inositol monophosphatase 0.0022 0.0011 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0123 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0069 0.0149
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0076 0.0077
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0009 0.001
Schistosoma mansoni tyrosine kinase 0.0038 0.0065 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.016 0.048 0.0535
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0074 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0104 0.0224
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.001 0.001
Schistosoma mansoni neuropeptide receptor 0.0119 0.034 0.0379
Schistosoma mansoni hypothetical protein 0.0119 0.034 0.0379
Brugia malayi neuropeptide F receptor 0.0119 0.034 0.0834
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0184 0.0563 0.0627
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0074 0.0181
Schistosoma mansoni lamin 0.0127 0.037 0.0412
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0161
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus neuropeptides capa receptor 0.0119 0.034 0.0379
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0211 0.0657 0.066
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0106 0.0299 0.03
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0074
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0001 0.0001
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0147 0.0438 0.1073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0065 0.0072
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.0021
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0035 0.0054 0.0054
Giardia lamblia DINP protein human, muc B family 0.0058 0.0134 0.0503
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0209 0.0648 0.0651
Brugia malayi hypothetical protein 0.0021 0.0009 0.0021
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0014 0.0013
Echinococcus multilocularis expressed conserved protein 0.0019 0.0002 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0014 0.004
Echinococcus multilocularis cpg binding protein 0.0081 0.0214 0.0238
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0211 0.0657 0.1977
Brugia malayi PHD-finger family protein 0.0023 0.0014 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0022
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0001 0.0003
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0069 0.0077
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0211 0.0657 0.2898
Loa Loa (eye worm) hypothetical protein 0.0056 0.0128 0.0313
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0019 0.0002 0.0002
Trypanosoma cruzi Emopamil binding protein, putative 0.029 0.0924 0.0928
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.001 0.0027
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.0021
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0035 0.0054 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Schistosoma mansoni beta-mannosidase 0.0084 0.0222 0.0247
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0049 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0125 0.0362 0.0887
Brugia malayi Protein kinase domain containing protein 0.0048 0.0099 0.0243
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.0931 0.0936
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0119 0.034 0.0834
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2939 0.9947 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0211 0.0657 0.2023
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0041
Loa Loa (eye worm) TK/EGFR protein kinase 0.0147 0.0438 0.1075
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0069 0.0077
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.072 0.239 0.5862
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0091 0.0248 0.0249
Schistosoma mansoni mixed-lineage leukemia protein mll 0.017 0.0514 0.0573
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0069 0.0077
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0119 0.034 0.0379
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0211 0.0657 0.066
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.029 0.0924 0.0928
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0074 0.0082
Brugia malayi tailless protein 0.0019 0.0001 0.0002
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0026 0.0024 0.0052
Trichomonas vaginalis set domain proteins, putative 0.1384 0.4648 1
Echinococcus granulosus tm gpcr rhodopsin 0.0931 0.3108 0.3465
Plasmodium vivax glutathione reductase, putative 0.0971 0.3244 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0119 0.034 0.0379
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0027
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0091 0.0248 0.0276
Brugia malayi Dopamine receptor 0.0119 0.034 0.0834
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0034 0.0051 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0069 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0088
Schistosoma mansoni transcription factor LCR-F1 0.0031 0.0043 0.0048
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0233 0.0259
Schistosoma mansoni sulfide quinone reductase 0.0211 0.0657 0.0732
Echinococcus multilocularis survival motor neuron protein 1 0.0848 0.2824 0.3149
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0071 0.0174
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0023 0.0023
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0038 0.0065 0.0072
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0001 0.0002
Echinococcus granulosus alpha 1A adrenergic receptor 0.0119 0.034 0.0379
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.03 0.0644
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0012 0.0036
Loa Loa (eye worm) helicase 0.0022 0.0012 0.003
Echinococcus granulosus cGMP dependent protein kinase 1 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Brugia malayi calmodulin 0.0026 0.0024 0.0059
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0211 0.0657 0.2898
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0119 0.034 0.0834
Schistosoma mansoni amine GPCR 0.0119 0.034 0.0379
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0023 0.0026
Schistosoma mansoni Replicative DNA helicase 0.0337 0.1084 0.1208
Echinococcus multilocularis tyrosine protein kinase HCK 0.003 0.004 0.0045
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0041 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0069 0.0077
Mycobacterium leprae Probable monophosphatase 0.0022 0.0011 0.0032
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.03 0.1313
Trichomonas vaginalis glutathione reductase, putative 0.0797 0.265 0.57
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0023 0.0085
Echinococcus granulosus PHD finger protein rhinoceros 0.0056 0.0128 0.0142
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0931 0.0936
Brugia malayi eukaryotic initiation factor 4A 0.0026 0.0024 0.0059
Onchocerca volvulus 0.0119 0.034 0.0731
Mycobacterium ulcerans hypothetical protein 0.0211 0.0657 0.2478
Leishmania major cytochrome p450-like protein 0.0025 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0002 0.0004
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0074 0.0082
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0211 0.0657 0.1412
Echinococcus granulosus peptide allatostatin:somatostatin 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.017
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0457 0.0509
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0072 0.0153
Brugia malayi intermediate filament protein 0.0127 0.037 0.0906
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0107 0.0229
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0207 0.0445
Brugia malayi SRC-1 0.0038 0.0065 0.0159
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0119 0.034 0.0379
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0043 0.0084 0.0314
Trypanosoma cruzi PAB1-binding protein , putative 0.0073 0.0186 0.0187
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0211 0.0657 0.0732
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0026 0.0024 0.009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0277 0.0879 0.2157
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0076 0.0077
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0074 0.0082
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.0438 0.0488
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0061 0.0146 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0074 0.018
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0202 0.0435
Loa Loa (eye worm) doublecortin family protein 0.0077 0.0199 0.0489
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0074 0.0082
Schistosoma mansoni amine GPCR 0.0119 0.034 0.0379
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0022 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2712 0.9173 0.9173
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0211 0.0657 0.0656
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0167 0.0504 0.0562
Trichomonas vaginalis glycoside hydrolase, putative 0.0259 0.0817 0.1758
Leishmania major NADH dehydrogenase, putative 0.0211 0.0657 0.066
Loa Loa (eye worm) hypothetical protein 0.0057 0.0132 0.0324
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0099 0.0244
Brugia malayi Tachykinin-like peptides receptor 99D 0.0119 0.034 0.0834
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0797 0.265 0.6499
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0074 0.018
Schistosoma mansoni glutamate synthase 0.0211 0.0657 0.0732
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.03 0.0334
Brugia malayi Latrophilin receptor protein 2 0.0088 0.0235 0.0575
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0024 0.0052
Onchocerca volvulus 0.0119 0.034 0.0731
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0119 0.034 0.0379
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0107 0.0328
Echinococcus granulosus biogenic amine 5HT receptor 0.0119 0.034 0.0379
Schistosoma mansoni disulfide oxidoreductase 0.0211 0.0657 0.0732
Onchocerca volvulus 0.0022 0.001 0.0021
Trypanosoma cruzi Emopamil binding protein, putative 0.029 0.0924 0.0928
Onchocerca volvulus 0.003 0.0039 0.0083
Brugia malayi PHD-finger family protein 0.0056 0.0128 0.0313
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.03 0.1313
Onchocerca volvulus 0.0073 0.0186 0.0399
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0023 0.0023
Plasmodium vivax calmodulin, putative 0.0026 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0176 0.0535 0.1313
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0035 0.0054 0.0133
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0035 0.0106
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0201 0.0224
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0119 0.034 0.0379
Echinococcus granulosus tyrosine protein kinase HCK 0.003 0.004 0.0045
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0107 0.0119
Brugia malayi G-protein coupled receptor 0.0119 0.034 0.0834
Loa Loa (eye worm) hypothetical protein 0.0148 0.0442 0.1085
Entamoeba histolytica beta-galactosidase, putative 0.0175 0.0532 0.2343
Schistosoma mansoni cytochrome P450 0.0025 0.0023 0.0025
Brugia malayi Cytochrome P450 family protein 0.0043 0.0084 0.0204
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0074 0.0082
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.03 0.0301
Trichomonas vaginalis glucosylceramidase, putative 0.072 0.239 0.5141
Brugia malayi Cytochrome P450 family protein 0.0025 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0142 0.0536
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0011
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0012 0.0037
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0089 0.0275
Trichomonas vaginalis abcb9, putative 0.0022 0.001 0.0021
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0086 0.023 0.0256
Brugia malayi Egg laying defective protein 4 0.0019 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni neuropeptide receptor 0.0119 0.034 0.0379
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0072 0.0153
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0028 0.0032 0.0032
Trichomonas vaginalis abcb9, putative 0.0022 0.001 0.0021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0209 0.0648 0.1393
Echinococcus multilocularis muscleblind protein 0.0144 0.0429 0.0477
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0074 0.0082
Loa Loa (eye worm) hypothetical protein 0.0211 0.0657 0.1611
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2468 0.8342 0.8386
Leishmania major cathepsin L-like protease 0.0056 0.0126 0.0126
Brugia malayi nuclear receptor NHR-88 0.0019 0.0001 0.0002
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0069 0.0169
Echinococcus multilocularis expressed protein 0.076 0.2523 0.2813
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0211 0.0657 0.0732
Toxoplasma gondii hypothetical protein 0.004 0.0074 0.0226
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Echinococcus granulosus inositol monophosphatase 0.0022 0.0011 0.0012
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0337 0.1084 0.4061
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0183 0.0204
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0022 0.0011 0.0011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2153 0.7268 0.7306
Toxoplasma gondii LsmAD domain-containing protein 0.0073 0.0186 0.0573
Echinococcus granulosus cGMP dependent protein kinase 1 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0012 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0105 0.0224
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0039 0.0083
Entamoeba histolytica calmodulin, putative 0.0026 0.0024 0.0091
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0012 0.0013
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0211 0.0657 0.2478
Echinococcus granulosus tumor protein p63 0.1014 0.3391 0.3781
Schistosoma mansoni hypothetical protein 0.0031 0.0043 0.0048
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0069 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0121 0.0259
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0069 0.0077
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0069 0.0077
Echinococcus granulosus chromobox protein 1 0.0079 0.0207 0.023
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0072 0.0153
Echinococcus multilocularis microtubule associated protein 2 0.2652 0.8969 1
Entamoeba histolytica hypothetical protein 0.0031 0.0043 0.0175
Echinococcus multilocularis serotonin transporter 0.0237 0.0745 0.083
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0001 0.0002
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0093 0.0228
Loa Loa (eye worm) CHromoDomain protein family member 0.0027 0.0027 0.0067
Schistosoma mansoni myosin xvIII 0.0119 0.034 0.0379
Schistosoma mansoni voltage-gated potassium channel 0.016 0.048 0.0535
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.008 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0029 0.0033
Echinococcus multilocularis epidermal growth factor receptor 0.008 0.0208 0.0231
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0211 0.0657 0.0732
Trichomonas vaginalis apoptosis inducing factor, putative 0.0211 0.0657 0.1412
Brugia malayi Heterochromatin protein 1 0.0079 0.0207 0.0507
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus lamin dm0 0.0127 0.037 0.0412
Leishmania major hypothetical protein, conserved 0.0211 0.0657 0.066
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0089 0.0275
Loa Loa (eye worm) intermediate filament protein 0.0127 0.037 0.0906
Brugia malayi putative neuropeptide receptor NPR1 0.0119 0.034 0.0834
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0044 0.0094
Plasmodium falciparum phd finger protein, putative 0.0056 0.0128 0.0393
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0074 0.0181
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0194 0.0597 0.2631
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.006
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0119 0.034 0.0379
Loa Loa (eye worm) TYRA-2 protein 0.0119 0.034 0.0835
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0457 0.0509
Brugia malayi Serotonin receptor 0.0119 0.034 0.0834
Trichomonas vaginalis calmodulin, putative 0.0026 0.0024 0.0052
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0074 0.018
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.03 0.0334
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0088 0.0235 0.0262
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Loa Loa (eye worm) AGC/PKG protein kinase 0.0019 0.0002 0.0004
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0086 0.0228 0.0254
Schistosoma mansoni microtubule-associated protein tau 0.2652 0.8969 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0033 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.003 0.0039 0.0095
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0038 0.0065 0.0072
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0931 0.0936
Entamoeba histolytica P-glycoprotein-2 0.0022 0.001 0.0027
Trichomonas vaginalis glutamate synthase, putative 0.0211 0.0657 0.1412
Echinococcus multilocularis chromobox protein 1 0.0079 0.0207 0.023
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.0074 0.018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0028 0.0032 0.0036
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0409 0.1329 0.1481
Toxoplasma gondii hypothetical protein 0.004 0.0074 0.0226
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0107 0.0229
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0147 0.0436 0.1069
Onchocerca volvulus 0.004 0.0074 0.0158
Schistosoma mansoni hypothetical protein 0.0022 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0065 0.0072
Onchocerca volvulus 0.0119 0.034 0.0731
Trypanosoma cruzi PAB1-binding protein , putative 0.0073 0.0186 0.0187
Echinococcus granulosus hyperpolarization activated cyclic 0.0033 0.0049 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Schistosoma mansoni hypothetical protein 0.0022 0.0011 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0074 0.0158
Leishmania major DNA polymerase kappa, putative 0.0058 0.0134 0.0134
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0211 0.0657 0.2478
Plasmodium vivax RNA helicase-1, putative 0.0026 0.0024 0.0074
Onchocerca volvulus 0.0019 0.0001 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0012 0.0013
Brugia malayi Intermediate filament tail domain containing protein 0.0127 0.037 0.0906
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0127 0.037 0.0906
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0183 0.0204
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0012 0.0037
Echinococcus granulosus neuropeptides capa receptor 0.0119 0.034 0.0379
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0041 0.0045
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0074 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0002 0.0002
Echinococcus granulosus neuropeptide FF receptor 2 0.0119 0.034 0.0379
Echinococcus granulosus Chromobox protein 3 0.0022 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0086 0.021
Schistosoma mansoni histamine h1 receptor 0.0119 0.034 0.0379
Echinococcus multilocularis jun protein 0.0167 0.0504 0.0562
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0209 0.0648 0.2857
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0066 0.0066
Echinococcus granulosus insulin receptor 0.0048 0.0099 0.011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.0248 0.0608
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0119 0.034 0.0379
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0184 0.0396
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0211 0.0657 0.2898
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus carbonic anhydrase II 0.0147 0.0438 0.0488
Toxoplasma gondii kinesin motor domain-containing protein 0.0023 0.0014 0.0043
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0027
Plasmodium vivax heterochromatin protein 1, putative 0.0022 0.0012 0.0037
Schistosoma mansoni adenoreceptor 0.0119 0.034 0.0379
Schistosoma mansoni 60S ribosomal protein L21 0.0027 0.0029 0.0033
Trypanosoma brucei NADH dehydrogenase 0.0211 0.0657 0.066
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0119 0.034 0.0379
Echinococcus multilocularis lamin 0.0127 0.037 0.0412
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.018
Echinococcus multilocularis isocitrate dehydrogenase 0.0028 0.0032 0.0036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0012 0.0026
Echinococcus granulosus hyperpolarization activated cyclic 0.0033 0.0049 0.0054
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0396 0.1284 0.1432
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0023 0.0023
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0074 0.0082
Echinococcus granulosus survival motor neuron protein 1 0.0848 0.2824 0.3149
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.03 0.0902
Schistosoma mansoni cpg binding protein 0.0081 0.0214 0.0238
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0897 0.2991 0.299
Entamoeba histolytica hypothetical protein 0.0022 0.0012 0.0036
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0057 0.0132 0.0284
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0023 0.0085
Loa Loa (eye worm) acetyltransferase 0.0153 0.0457 0.112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Echinococcus granulosus cpg binding protein 0.0081 0.0214 0.0238
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0107 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0074 0.0082
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0797 0.265 0.8167
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0142 0.0158
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.001 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0074
Schistosoma mansoni multidrug resistance protein 0.0022 0.001 0.0011
Echinococcus multilocularis RUN 0.0077 0.0199 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0107 0.0229
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0176 0.0535 0.0597
Echinococcus granulosus fmrfamide receptor 0.0119 0.034 0.0379
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0062 0.0069
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0071 0.0173
Schistosoma mansoni tyrosine kinase 0.0147 0.0438 0.0489
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.03 0.0334
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0119 0.034 0.0835
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Echinococcus granulosus GPCR family 2 0.0088 0.0235 0.0262
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Onchocerca volvulus 0.0119 0.034 0.0731
Schistosoma mansoni neuropeptide F-like receptor 0.0119 0.034 0.0379
Trypanosoma brucei DNA polymerase IV, putative 0.0072 0.0182 0.0182
Loa Loa (eye worm) blistered cuticle protein 3 0.0148 0.044 0.1079
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0106 0.0299 0.0732
Giardia lamblia Glutamate synthase 0.0211 0.0657 0.2478
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0053 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0069 0.0077
Echinococcus multilocularis sodium channel protein 0.0086 0.0228 0.0254
Brugia malayi hypothetical protein 0.004 0.0074 0.018
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0012 0.0037
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1137 0.381 0.383
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0173 0.0526 0.1288
Mycobacterium ulcerans dehydrogenase 0.0211 0.0657 0.2478
Loa Loa (eye worm) hypothetical protein 0.0156 0.0467 0.1146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0123 0.0263
Echinococcus granulosus inositol monophosphatase 1 0.0209 0.0648 0.0722
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0074 0.018
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.011 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0088
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0119 0.034 0.0379
Echinococcus granulosus 7TM GPCR rhodopsin 0.0119 0.034 0.0379
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0011
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2468 0.8342 0.8386
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.0181
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.001 0.0011
Echinococcus multilocularis WD repeat containing protein 48 0.0109 0.0306 0.0341
Echinococcus granulosus tm gpcr rhodopsin 0.0626 0.207 0.2308
Schistosoma mansoni tyrosine kinase 0.0078 0.0202 0.0224
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0069 0.0077
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.0207 0.0508
Loa Loa (eye worm) hypothetical protein 0.0109 0.0308 0.0756
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0119 0.034 0.0379
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0797 0.265 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0797 0.265 0.2954
Echinococcus multilocularis chromobox protein 2 0.0022 0.0012 0.0013
Schistosoma mansoni cpg binding protein 0.0081 0.0214 0.0238
Brugia malayi conserved hypotetical protein 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.046 0.046
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0142 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0119 0.034 0.0379
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Schistosoma mansoni zinc finger protein 0.0019 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.0176 0.0535 0.1312
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0931 0.3108 0.3465
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0022
Brugia malayi Protein cec-1. 0.0022 0.0012 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0107 0.0229
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0176 0.0535 0.0597
Echinococcus multilocularis musashi 0.0127 0.037 0.0412
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0039 0.0044
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0041 0.0101
Trypanosoma cruzi DNA repair protein, putative 0.0029 0.0035 0.0035
Echinococcus multilocularis Chromo domain 0.0022 0.0012 0.0013
Schistosoma mansoni chromobox protein 0.0079 0.0207 0.023
Loa Loa (eye worm) hypothetical protein 0.0059 0.0138 0.0337
Loa Loa (eye worm) hypothetical protein 0.0277 0.0879 0.2157
Schistosoma mansoni chromobox protein 0.0022 0.0012 0.0013
Entamoeba histolytica thioredoxin reductase, putative 0.0211 0.0657 0.2898
Schistosoma mansoni lipoxygenase 0.0396 0.1284 0.1432
Schistosoma mansoni hypothetical protein 0.0946 0.3159 0.3522
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0312 0.0998 0.0997
Echinococcus multilocularis inositol monophosphatase 1 0.0209 0.0648 0.0722
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0091 0.0248 0.1083
Entamoeba histolytica hypothetical protein 0.0023 0.0014 0.0042
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0048 0.0054
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0038 0.0065 0.0072
Schistosoma mansoni hypothetical protein 0.0047 0.0095 0.0106
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0014 0.0041
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.03 0.113
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Trypanosoma cruzi NADH dehydrogenase, putative 0.0211 0.0657 0.066
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.0657 0.066
Mycobacterium ulcerans monophosphatase 0.0022 0.0011 0.0041
Echinococcus multilocularis ubiquitin specific protease 41 0.0106 0.0299 0.0333
Mycobacterium leprae Conserved hypothetical protein 0.0025 0.0023 0.0068
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0028 0.0032 0.0032
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.0069 0.017
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0035 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0039 0.0083
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.0074 0.0082
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0053 0.0059
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0147 0.0438 0.044
Trypanosoma brucei cytochrome P450, putative 0.0043 0.0084 0.0084
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0041
Plasmodium falciparum kinesin-5 0.0023 0.0014 0.0043
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0019 0 0.0001
Echinococcus multilocularis chromobox protein 1 0.0079 0.0207 0.023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) serotonin transporter b 0.0237 0.0745 0.1826
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0211 0.0657 0.066
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0147 0.0438 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0069 0.0149
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0041
Schistosoma mansoni jumonji domain containing protein 0.0146 0.0434 0.0484
Treponema pallidum thioredoxin reductase (trxB) 0.0211 0.0657 0.2478
Trichomonas vaginalis mercuric reductase, putative 0.0797 0.265 0.57
Entamoeba histolytica P-glycoprotein-5 0.0022 0.001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0128 0.0372 0.0913
Onchocerca volvulus 0.004 0.0074 0.0158
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trypanosoma cruzi calmodulin 0.0026 0.0024 0.0024
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0233 0.0259
Echinococcus granulosus Chromo domain 0.0022 0.0012 0.0013
Loa Loa (eye worm) TK protein kinase 0.0034 0.0053 0.013
Leishmania major hypothetical protein, conserved 0.0073 0.0186 0.0187
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0038 0.0065 0.0072
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0012 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0259 0.0817 0.1758
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0033 0.0049 0.0054
Trypanosoma cruzi NADH dehydrogenase, putative 0.0211 0.0657 0.066
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0099 0.011
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0797 0.265 0.2664
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0089 0.0192
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0167 0.0504 0.0562
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0028 0.0032 0.0036
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0088
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Schistosoma mansoni nuclear receptor 0.0019 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0442 0.0493
Trichomonas vaginalis beta-galactosidase, putative 0.0259 0.0817 0.1758
Leishmania major DNA polymerase eta, putative 0.0051 0.011 0.011
Giardia lamblia NADH oxidase lateral transfer candidate 0.0797 0.265 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0897 0.2991 0.299
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0035 0.0054 0.006
Plasmodium falciparum thioredoxin reductase 0.0797 0.265 0.8167
Brugia malayi hypothetical protein 0.0039 0.0069 0.0169
Schistosoma mansoni hypothetical protein 0.0211 0.0657 0.0732
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0035 0.0054 0.0132
Entamoeba histolytica hypothetical protein 0.0031 0.0043 0.0175
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Brugia malayi Bromodomain containing protein 0.006 0.014 0.0344
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus multilocularis dna polymerase kappa 0.0079 0.0205 0.0229
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0127 0.037 0.0906
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0797 0.265 0.265
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.0226
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0185 0.0185
Echinococcus multilocularis hyperpolarization activated cyclic 0.0033 0.0049 0.0054
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0069 0.0077
Schistosoma mansoni survival motor neuron protein 0.0173 0.0526 0.0586
Echinococcus granulosus expressed protein 0.076 0.2523 0.2813
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.001 0.003
Brugia malayi nuclear receptor RXR 0.0021 0.0009 0.0021
Echinococcus granulosus jumonji domain containing protein 0.0078 0.0203 0.0226
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0023 0.0085
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Echinococcus granulosus somatostatin receptor 0.0119 0.034 0.0379
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0014 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.001 0.0021
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0014 0.005
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0106 0.0299 0.0333
Onchocerca volvulus 0.0173 0.0526 0.113
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0119 0.034 0.0379
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.004 0.0085
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0211 0.0657 0.2898
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0041 0.0041
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.0074 0.0082
Schistosoma mansoni tyrosine kinase 0.0078 0.0202 0.0224
Brugia malayi neuropeptide F receptor 0.0119 0.034 0.0834
Plasmodium falciparum eukaryotic initiation factor 4A 0.0026 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0581 0.1916 0.47
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0154 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0211 0.0657 0.066
Schistosoma mansoni growth hormone secretagogue receptor 0.0119 0.034 0.0379
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0024 0.0027
Schistosoma mansoni hypothetical protein 0.1096 0.367 0.4092
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0142 0.0143
Schistosoma mansoni chromobox protein 0.0022 0.0012 0.0013
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0212 0.0658 0.1415
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0211 0.0657 0.2023
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0115 0.0246
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0312 0.0998 0.0997
Giardia lamblia Fructose-bisphosphate aldolase 0.0531 0.1746 0.6587
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0068 0.0169 0.0413
Echinococcus multilocularis fmrfamide receptor 0.0119 0.034 0.0379
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0119 0.034 0.0835
Trypanosoma brucei PAB1-binding protein , putative 0.0073 0.0186 0.0187
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.0074 0.0082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0049 0.0105
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Treponema pallidum sodium- and chloride- dependent transporter 0.0237 0.0745 0.2809
Mycobacterium leprae Conserved hypothetical protein 0.0993 0.332 1
Leishmania major hypothetical protein, conserved 0.029 0.0924 0.0928
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0074 0.018
Brugia malayi hypothetical protein 0.0848 0.2824 0.6927
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0134 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0211 0.0657 0.0732
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0023 0.0026
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0312 0.0998 0.0997
Onchocerca volvulus 0.0026 0.0024 0.0052
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0091 0.0248 0.0249
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0012 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.008 0.008
Schistosoma mansoni cellular tumor antigen P53 0.0148 0.0442 0.0493
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0035 0.0106
Echinococcus multilocularis neuropeptide receptor 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.0051 0.011 0.0269
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0035 0.0074
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0001 0.0001
Onchocerca volvulus 0.004 0.0074 0.0158
Schistosoma mansoni hypothetical protein 0.0946 0.3159 0.3522
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0074 0.0082
Schistosoma mansoni glutamate synthase 0.0211 0.0657 0.0732
Onchocerca volvulus Calmodulin homolog 0.0026 0.0024 0.0052
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0211 0.0657 0.1977
Echinococcus granulosus eukaryotic initiation factor 4A 0.0026 0.0024 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0074
Echinococcus granulosus thioredoxin glutathione reductase 0.0971 0.3244 0.3617
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0312 0.0998 0.3004
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0247 0.0777 0.1905
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0023 0.0085
Giardia lamblia DNA repair protein RAD52 0.0681 0.2256 0.8516
Toxoplasma gondii isocitrate dehydrogenase 0.0028 0.0032 0.0098
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0012 0.0026
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0029 0.0035 0.0035
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0023 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.072 0.239 0.5141
Schistosoma mansoni neuropeptide F-like receptor 0.0119 0.034 0.0379
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0797 0.265 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0035 0.0106
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0107 0.0107
Brugia malayi polk-prov protein 0.0044 0.0086 0.021
Plasmodium falciparum glutathione reductase 0.0797 0.265 0.8167
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0154 0.0154
Onchocerca volvulus 0.0119 0.034 0.0731
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0211 0.0657 0.066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0028 0.0032 0.0036
Trichomonas vaginalis ABC transporter, putative 0.0022 0.001 0.0021
Schistosoma mansoni amine GPCR 0.0606 0.2001 0.2231
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.008 0.008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0119 0.034 0.0834
Loa Loa (eye worm) hypothetical protein 0.0034 0.0051 0.0125
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.03 0.0735
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.017
Mycobacterium ulcerans monophosphatase CysQ 0.0022 0.0011 0.0041
Brugia malayi nuclear receptor RXR 0.0019 0.0001 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0072 0.0153
Echinococcus multilocularis L aminoadipate semialdehyde 0.008 0.021 0.0234
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0035 0.0054 0.0054
Brugia malayi PXA domain containing protein 0.0039 0.0069 0.0169
Trichomonas vaginalis beta-mannosidase, putative 0.0084 0.0222 0.0478
Brugia malayi Isocitrate dehydrogenase 0.0028 0.0032 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0105 0.0225
Echinococcus granulosus RUN 0.0077 0.0199 0.0222
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0035 0.0054 0.0054
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0119 0.034 0.0379
Treponema pallidum replicative DNA helicase (dnaB) 0.0337 0.1084 0.4091
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0069 0.0149
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0074 0.0082
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Brugia malayi MAP kinase sur-1 0.005 0.0107 0.0261
Schistosoma mansoni tyrosine kinase 0.008 0.0208 0.0231
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0027 0.0027 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.017
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0026 0.0024 0.0091
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0086 0.023 0.0256
Brugia malayi RE15519p 0.0119 0.034 0.0834
Toxoplasma gondii selenide, water dikinase 0.0211 0.0657 0.2023
Echinococcus multilocularis insulin receptor 0.0048 0.0099 0.011
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0211 0.0657 0.066
Brugia malayi CHD4 protein 0.0027 0.0027 0.0066
Echinococcus multilocularis g-protein coupled receptor 0.0119 0.034 0.0379
Loa Loa (eye worm) neuropeptide F receptor 0.0119 0.034 0.0835
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0022
Echinococcus granulosus allatostatin A receptor 0.0119 0.034 0.0379
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0023 0.0085
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0209 0.0648 0.0651
Loa Loa (eye worm) phosphofructokinase 0.0107 0.03 0.0735
Onchocerca volvulus 0.0211 0.0657 0.1412
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0176 0.0535 0.1649
Echinococcus granulosus rhodopsin orphan GPCR 0.0119 0.034 0.0379
Loa Loa (eye worm) hypothetical protein 0.0049 0.0105 0.0257
Schistosoma mansoni hypothetical protein 0.0119 0.034 0.0379
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0797 0.265 0.2664
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0211 0.0657 0.066
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0027 0.0027 0.003
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0211 0.0657 0.2898
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0129 0.0315
Echinococcus granulosus chromobox protein 2 0.0022 0.0012 0.0013
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.001 0.0011
Schistosoma mansoni lamin 0.0127 0.037 0.0412
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.0024 0.0027
Entamoeba histolytica P-glycoprotein-1 0.0022 0.001 0.0027
Brugia malayi Dopamine receptor protein 2 0.0119 0.034 0.0834
Echinococcus multilocularis GPCR, family 2 0.0088 0.0235 0.0262
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0023 0.0085
Echinococcus multilocularis PHD finger protein rhinoceros 0.0056 0.0128 0.0142
Schistosoma mansoni tyrosine kinase 0.008 0.0208 0.0231
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0147 0.0438 0.1073
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Trypanosoma cruzi cruzipain precursor, putative 0.0056 0.0126 0.0126
Leishmania major myo-inositol-1 phosphatase, putative 0.0022 0.0011 0.0011
Onchocerca volvulus 0.0077 0.0199 0.0427
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0209 0.0648 0.2405
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.003
Mycobacterium ulcerans ferredoxin reductase 0.0211 0.0657 0.2478
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.001 0.0025
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0022 0.0011 0.0012
Mycobacterium tuberculosis Monophosphatase CysQ 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0311 0.0997 0.2445
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0071 0.0079
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0119 0.034 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.002 0.0043
Loa Loa (eye worm) G-protein coupled receptor 0.0119 0.034 0.0835
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0211 0.0657 0.2478
Loa Loa (eye worm) hypothetical protein 0.008 0.021 0.0516
Echinococcus multilocularis neuropeptide receptor 0.0119 0.034 0.0379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Echinococcus granulosus jun protein 0.0167 0.0504 0.0562
Leishmania major dihydrolipoamide dehydrogenase, putative 0.2939 0.9947 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0138 0.0337
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0009 0.001
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0119 0.034 0.0379
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0457 0.1119
Brugia malayi protein-tyrosine kinase 0.0034 0.0053 0.0129
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0207 0.0445
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0035 0.0054 0.006
Mycobacterium ulcerans recombinase A 0.0094 0.0257 0.0969
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0074 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0012 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0074 0.018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0797 0.265 0.2664
Schistosoma mansoni hypothetical protein 0.0025 0.0023 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Loa Loa (eye worm) hypothetical protein 0.0144 0.0429 0.1051
Brugia malayi F/Y-rich N-terminus family protein 0.0048 0.0101 0.0247
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0061 0.0146 0.0162
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0211 0.0657 0.2023
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.018
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0074 0.0181
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0069 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0086 0.0086
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0022 0.0011 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0119 0.034 0.0379
Schistosoma mansoni neuropeptide f receptor 76f 0.0119 0.034 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0086 0.023 0.0256
Schistosoma mansoni hypothetical protein 0.0077 0.0199 0.0222
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.0069 0.0149
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0023 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0134 0.0134
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0051 0.011 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0023 0.0023
Echinococcus granulosus FTZ F1 alpha 0.004 0.0074 0.0082
Onchocerca volvulus 0.0119 0.034 0.0731
Brugia malayi cytochrome P450 0.0025 0.0023 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0211 0.0657 0.0656
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0035 0.013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0074 0.018
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0074 0.018
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0123 0.0263
Giardia lamblia Calmodulin 0.0026 0.0024 0.0091
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0086 0.023 0.0256
Brugia malayi CXXC zinc finger family protein 0.0077 0.0199 0.0487
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Toxoplasma gondii isocitrate dehydrogenase 0.0028 0.0032 0.0098
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0001 0.0001
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0074 0.0082
Brugia malayi hypothetical protein 0.0077 0.0199 0.0489
Schistosoma mansoni tyrosine kinase 0.0048 0.0099 0.011
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0051 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0086 0.0086
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0001 0.0001
Brugia malayi Adenylyl cyclase protein 0.0076 0.0197 0.0482
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0024 0.0027
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0022 0.001 0.0037
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0012 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0069 0.0149
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0211 0.0657 0.2478
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Echinococcus multilocularis orexin receptor type 2 0.0119 0.034 0.0379
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0069 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0074 0.018
Brugia malayi Beta-glucuronidase precursor 0.024 0.0753 0.1846
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0035 0.0054 0.006
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0211 0.0657 0.1412
Trichomonas vaginalis inositol monophosphatase, putative 0.0022 0.0011 0.0023
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0093 0.0104
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0154 0.0377
Treponema pallidum oxidoreductase 0.0211 0.0657 0.2478
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0023 0.0085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0119 0.034 0.0379
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0033 0.0049 0.0054
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0211 0.0657 0.2023
Loa Loa (eye worm) PHD-finger family protein 0.0056 0.0128 0.0313
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0038 0.0065 0.0072
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni hypothetical protein 0.0153 0.0457 0.0509
Loa Loa (eye worm) norepinephrine transporter 0.0237 0.0745 0.1826
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0074 0.018
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0026 0.0024 0.0027
Treponema pallidum NADH oxidase 0.0797 0.265 1
Echinococcus multilocularis lamin dm0 0.0127 0.037 0.0412
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0211 0.0657 0.066
Plasmodium falciparum ferrodoxin reductase-like protein 0.0211 0.0657 0.2023
Echinococcus multilocularis 0.0025 0.0023 0.0025
Mycobacterium ulcerans glutamate synthase subunit beta 0.0211 0.0657 0.2478
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0107 0.0262
Schistosoma mansoni hypothetical protein 0.0088 0.0235 0.0262
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Leishmania major protein kinase, putative 0.0019 0.0002 0.0002
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0211 0.0657 0.066
Entamoeba histolytica deoxycytidyl transferase, putative 0.0051 0.011 0.047
Brugia malayi multidrug resistance protein 3 0.0022 0.001 0.0024
Echinococcus granulosus kinesin family 1 0.0176 0.0535 0.0596
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0074 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0074 0.0082
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0211 0.0657 0.1611
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.0074 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0107 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2468 0.8342 0.8386
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0312 0.0998 0.0997
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0211 0.0657 0.161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0038 0.0065 0.0072
Loa Loa (eye worm) kinesin-like protein KLP2 0.0023 0.0014 0.0035
Brugia malayi Doublecortin family protein 0.0077 0.0199 0.0489
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0074 0.0082
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0069 0.0169
Loa Loa (eye worm) hypothetical protein 0.0106 0.0299 0.0732
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0211 0.0657 0.0732
Schistosoma mansoni tyrosine kinase 0.0048 0.0099 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0184 0.0396
Brugia malayi Furin-like cysteine rich region family protein 0.0147 0.0438 0.1075
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0091 0.0248 0.0276
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni terminal deoxycytidyl transferase 0.0051 0.011 0.0122
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0854 0.2846 0.3173
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0033 0.0049 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0024
Entamoeba histolytica kinesin, putative 0.0023 0.0014 0.0045
Schistosoma mansoni neuropeptide receptor 0.0119 0.034 0.0379
Trypanosoma brucei trypanothione reductase 0.0971 0.3244 0.3261
Schistosoma mansoni inositol monophosphatase 0.0209 0.0648 0.0722
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.0084 0.0084
Treponema pallidum recombinase A 0.0094 0.0257 0.0969
Onchocerca volvulus 0.0119 0.034 0.0731
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0531 0.1746 0.3755
Trypanosoma brucei hypothetical protein, conserved 0.0211 0.0657 0.066
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Leishmania major calmodulin, putative 0.0026 0.0024 0.0024
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0012 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.072 0.239 0.5141
Plasmodium falciparum transporter, putative 0.004 0.0074 0.0226
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0069 0.0077
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0051 0.011 0.0122
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0106 0.0299 0.1308
Mycobacterium tuberculosis Probable dehydrogenase 0.0312 0.0998 0.0997
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.03 0.0735
Loa Loa (eye worm) hypothetical protein 0.0525 0.1724 0.4229
Echinococcus multilocularis geminin 0.0946 0.3159 0.3522
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0035 0.0074
Echinococcus multilocularis dna polymerase eta 0.0051 0.011 0.0122
Onchocerca volvulus 0.0148 0.0442 0.0951
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0026 0.0024 0.0024
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0027
Brugia malayi AKH receptor 0.0119 0.034 0.0834
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0119 0.034 0.0379
Echinococcus multilocularis neuropeptide receptor A26 0.1352 0.454 0.5061
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0211 0.0657 0.1412
Echinococcus granulosus dnaJ subfamily B 0.1096 0.367 0.4092
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0119 0.034 0.0379
Loa Loa (eye worm) SRC-1 0.0038 0.0065 0.016
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Schistosoma mansoni lipoxygenase 0.0257 0.0811 0.0904
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0211 0.0657 0.0732
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0022 0.0011 0.0023
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0211 0.0657 0.066
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0024 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Brugia malayi Muscleblind-like protein 0.0144 0.0429 0.105
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.001 0.0011
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0407 0.0409
Echinococcus granulosus orexin receptor type 2 0.0119 0.034 0.0379
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0053 0.0059
Mycobacterium tuberculosis Probable reductase 0.0312 0.0998 0.0997
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0185 0.0185
Toxoplasma gondii calmodulin, putative 0.0026 0.0024 0.0074
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0074 0.0082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0072 0.0153
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.0074 0.0082
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0069 0.0077
Echinococcus multilocularis conserved hypothetical protein 0.0677 0.2243 0.25
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0139 0.0298
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0076 0.0077
Schistosoma mansoni opsin-like receptor 0.0119 0.034 0.0379
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0091 0.0224
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0069 0.0173 0.0173
Giardia lamblia Thioredoxin reductase 0.0211 0.0657 0.2478
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0069 0.017
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0119 0.034 0.0834
Brugia malayi jmjC domain containing protein 0.0184 0.0563 0.138
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0014 0.0041
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0028 0.0032 0.0098
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0027
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0069 0.0173 0.0173
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0012 0.0026
Echinococcus multilocularis allatostatin A receptor 0.0119 0.034 0.0379
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0531 0.1746 0.7732
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0023 0.0085
Schistosoma mansoni opsin-like receptor 0.0119 0.034 0.0379
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0142 0.0158
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.0181
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0147 0.0438 0.0488
Schistosoma mansoni kinesin eg-5 0.0023 0.0014 0.0016
Brugia malayi hypothetical protein 0.0119 0.0343 0.0841
Echinococcus granulosus lamin 0.0127 0.037 0.0412
Schistosoma mansoni carbonic anhydrase 0.0034 0.0051 0.0056
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0035 0.0054 0.0132
Brugia malayi Melibiase family protein 0.0057 0.0132 0.0324
Loa Loa (eye worm) hypothetical protein 0.0848 0.2824 0.6927
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0168 0.0361
Brugia malayi Cytochrome P450 family protein 0.0045 0.0091 0.0223
Echinococcus granulosus ubiquitin specific protease 41 0.0106 0.0299 0.0333
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0142 0.0536
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0093 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Trichomonas vaginalis abcb9, putative 0.0022 0.001 0.0021
Echinococcus multilocularis inositol monophosphatase 0.0022 0.0011 0.0012
Onchocerca volvulus 0.0119 0.034 0.0731
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0106 0.0299 0.0333
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0022
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0057 0.0132 0.0147
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0001 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0022 0.0011 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0093 0.0104
Brugia malayi hypothetical protein 0.0131 0.0382 0.0937
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0797 0.265 0.8167
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0209 0.0648 0.1393
Mycobacterium ulcerans monoxygenase 0.0211 0.0657 0.2478
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0233 0.0259
Brugia malayi Dopamine receptor protein 1 0.0785 0.2611 0.6403
Entamoeba histolytica hypothetical protein 0.0039 0.0069 0.029
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.0931 0.0936
Brugia malayi G-protein coupled receptor 0.0119 0.034 0.0834
Echinococcus granulosus epidermal growth factor receptor 0.0147 0.0438 0.0489
Trichomonas vaginalis hypothetical protein 0.0022 0.0012 0.0026
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0035 0.0054 0.0166
Echinococcus granulosus microtubule associated protein 2 0.2652 0.8969 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0035 0.013
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0074 0.0082
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0211 0.0657 0.244
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0035 0.0054 0.0116
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0248 0.0608
Mycobacterium ulcerans hypothetical protein 0.0154 0.046 0.1737
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.001 0.0021
Entamoeba histolytica hypothetical protein 0.0031 0.0043 0.0175
Loa Loa (eye worm) hypothetical protein 0.1137 0.381 0.9344
Schistosoma mansoni hypothetical protein 0.0119 0.034 0.0379
Plasmodium falciparum amino acid transporter, putative 0.004 0.0074 0.0226
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi larval opioid receptor 0.0119 0.034 0.0834
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0074 0.0082
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0074 0.0082
Loa Loa (eye worm) CYP4Cod1 0.0043 0.0084 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0088
Schistosoma mansoni biogenic amine receptor 0.0119 0.034 0.0379
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0211 0.0657 0.2023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0211 0.0657 0.1412
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.001 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0056 0.0128 0.0393
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0184 0.0396
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0023 0.0023
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0069 0.0077
Echinococcus multilocularis muscleblind protein 1 0.0144 0.0429 0.0477
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.006
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.0069 0.0077
Trypanosoma brucei Emopamil binding protein, putative 0.029 0.0924 0.0928
Echinococcus multilocularis epidermal growth factor receptor 0.0147 0.0438 0.0489
Plasmodium falciparum thioredoxin reductase 0.0971 0.3244 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0074 0.0181
Schistosoma mansoni biogenic amine (5HT) receptor 0.0366 0.1184 0.132
Loa Loa (eye worm) hypothetical protein 0.0077 0.0199 0.0489
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Entamoeba histolytica hypothetical protein 0.0039 0.0069 0.029
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0013 0.0014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0088 0.0235 0.0576
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0056 0.0128 0.0142
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0107 0.0107
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0074 0.018
Brugia malayi 6-phosphofructokinase 0.0107 0.03 0.0735
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0035 0.0054 0.0116
Schistosoma mansoni thyroid hormone receptor 0.004 0.0074 0.0082
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0187 0.0573 0.1725
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0181
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0023 0.0023
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0106 0.0299 0.0333
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0091 0.0248 0.0276
Onchocerca volvulus 0.0119 0.034 0.0731
Schistosoma mansoni biogenic amine receptor 0.0119 0.034 0.0379
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0072 0.0153
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0107 0.0119
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0001 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0531 0.1746 0.7732
Echinococcus granulosus neuropeptide Y receptor 0.0119 0.034 0.0379
Echinococcus granulosus sodium channel protein 0.0086 0.0228 0.0254
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0033 0.0049 0.012
Entamoeba histolytica hypothetical protein 0.0022 0.0012 0.0036
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0074 0.0082
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0211 0.0657 0.161
Plasmodium falciparum ataxin-2 like protein, putative 0.0073 0.0186 0.0573
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0012 0.0036
Schistosoma mansoni chromobox protein 0.0079 0.0207 0.023
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0071 0.0174
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0033 0.0049 0.0054
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi glutamate synthase 0.0211 0.0657 0.161
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0144 0.0426 0.0916
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0069 0.0173 0.0173
Brugia malayi hypothetical protein 0.0077 0.0199 0.0489
Echinococcus granulosus lipoxygenase domain containing protein 0.0077 0.0199 0.0222
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0093 0.0104
Echinococcus granulosus neuropeptide receptor A26 0.1352 0.454 0.5061
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0211 0.0657 0.2478
Leishmania major eukaryotic initiation factor 4a, putative 0.0026 0.0024 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.0277 0.0879 0.2156
Brugia malayi latrophilin 2 splice variant baaae 0.0189 0.0581 0.1424
Brugia malayi G protein-coupled receptor F59B2.13 0.0119 0.034 0.0834
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2153 0.7268 0.7306
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0089 0.0192
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0023 0.0015 0.0045
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0089 0.0275
Leishmania major hypothetical protein, conserved 0.0211 0.0657 0.066
Loa Loa (eye worm) hypothetical protein 0.0046 0.0093 0.0229
Echinococcus multilocularis adenylate cyclase 9 0.0076 0.0197 0.0219
Leishmania major calmodulin, putative 0.0026 0.0024 0.0024
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.001 0.001
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0093 0.0104
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0407 0.0409
Echinococcus multilocularis sex peptide receptor 0.0119 0.034 0.0379
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0041 0.01
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0074 0.0082
Brugia malayi Inositol monophosphatase family protein 0.0022 0.0011 0.0026
Trypanosoma brucei DNA polymerase eta, putative 0.0051 0.011 0.011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.001 0.0021
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0211 0.0657 0.0656
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0074 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0002 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0106 0.0299 0.0333
Brugia malayi hypothetical protein 0.0021 0.0009 0.0021
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.029 0.0924 0.0928
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0012 0.0029
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0209 0.0648 0.2443
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.0074 0.0277
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.001 0.0021
Trypanosoma cruzi calmodulin, putative 0.0026 0.0024 0.0024
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.008 0.021 0.0515
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0077 0.0323
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0031 0.0043 0.0048
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0237 0.0745 0.083
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Echinococcus granulosus histone lysine methyltransferase setb 0.0176 0.0535 0.0597
Mycobacterium leprae putative cytochrome p450 0.0025 0.0023 0.0068
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0105 0.0224
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0211 0.0657 0.1412
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0023 0.0023
Brugia malayi ABC transporter family protein 0.0022 0.001 0.0024
Loa Loa (eye worm) adenylyl cyclase 3 0.0076 0.0197 0.0483
Trichomonas vaginalis glucosylceramidase, putative 0.0473 0.1546 0.3326
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0091 0.0248 0.0249
Brugia malayi ORL1-like opioid receptor 0.0119 0.034 0.0834
Loa Loa (eye worm) hypothetical protein 0.0237 0.0745 0.1826
Echinococcus granulosus adenylate cyclase 9 0.0076 0.0197 0.0219
Onchocerca volvulus 0.0019 0.0001 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0015 0.0045
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0033 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0001 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0119 0.034 0.0835
Leishmania major eukaryotic initiation factor 4a, putative 0.0026 0.0024 0.0024
Trypanosoma brucei unspecified product 0.0035 0.0056 0.0056
Loa Loa (eye worm) neuropeptide F receptor 0.0119 0.034 0.0835
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.011 0.0269
Echinococcus multilocularis serotonin receptor 0.0366 0.1184 0.132
Toxoplasma gondii hypothetical protein 0.0062 0.0147 0.0453
Mycobacterium ulcerans monophosphatase CysQ 0.0022 0.0011 0.0041
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0049 0.0054
Leishmania major hypothetical protein, conserved 0.0211 0.0657 0.066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.003
Onchocerca volvulus 0.008 0.021 0.0452
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0797 0.265 1
Brugia malayi G protein-coupled receptor 0.0119 0.034 0.0834
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0048 0.0054
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0035 0.013
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0076 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0184 0.0396
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0001 0.0003
Plasmodium vivax amine transporter, putative 0.004 0.0074 0.0226
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0012 0.0037
Onchocerca volvulus 0.0119 0.034 0.0731
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0024 0.0052
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0107 0.0107
Trypanosoma brucei C-8 sterol isomerase, putative 0.1137 0.381 0.383
Echinococcus granulosus g-protein coupled receptor 0.0119 0.034 0.0379
Echinococcus multilocularis 0.0045 0.0091 0.0101
Schistosoma mansoni opsin-like receptor 0.0119 0.034 0.0379
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0154 0.0154
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0026 0.0024 0.0024
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0027
Plasmodium vivax hypothetical protein, conserved 0.004 0.0074 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0119 0.034 0.0379
Onchocerca volvulus Glucosylceramidase homolog 0.0473 0.1546 0.3326
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0014 0.0041
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0259 0.082 0.082
Loa Loa (eye worm) solute carrier family 6 member 4 0.0237 0.0745 0.1826
Echinococcus multilocularis neuropeptides capa receptor 0.0119 0.034 0.0379
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2939 0.9947 1
Schistosoma mansoni inositol monophosphatase 0.0209 0.0648 0.0722
Trichomonas vaginalis inositol monophosphatase, putative 0.0209 0.0648 0.1393
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0065 0.0072
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0211 0.0657 0.161
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0023 0.0085
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0086 0.023 0.0256
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0041 0.0045
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0106 0.0299 0.0333
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0069 0.0077
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0026 0.0024 0.0074
Loa Loa (eye worm) carbonic anhydrase 3 0.0147 0.0438 0.1074
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0237 0.0745 0.1826
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0104 0.0224
Chlamydia trachomatis thioredoxin reductase 0.0211 0.0657 0.2478
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0026 0.0024 0.0027
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0071 0.0079
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0002 0.0006
Schistosoma mansoni hypothetical protein 0.0056 0.0128 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0205 0.0206
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0211 0.0657 0.0656
Mycobacterium tuberculosis Probable monophosphatase 0.0022 0.0011 0.0011
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0013 0.0014
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0211 0.0657 0.0732
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0012 0.0037
Brugia malayi PXA domain containing protein 0.0039 0.0069 0.0169
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.018
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.072 0.239 0.5141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0119 0.034 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0012 0.0026
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0074 0.0082
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0142 0.0142
Leishmania major cytochrome p450-like protein 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0119 0.034 0.0835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0145 0.0312
Loa Loa (eye worm) jmjC domain-containing protein 0.0116 0.0331 0.0813
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0022 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0237 0.0745 0.1826
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0277 0.0879 0.2156
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0211 0.0657 0.1412
Echinococcus granulosus g protein coupled receptor 0.0119 0.034 0.0379
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0233 0.0259
Loa Loa (eye worm) hypothetical protein 0.0237 0.0745 0.1826
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0147 0.0436 0.107
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0797 0.265 0.2954
Chlamydia trachomatis recombinase RecA 0.0094 0.0257 0.0969
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0119 0.034 0.0835
Trypanosoma brucei protein kinase, putative 0.005 0.0107 0.0107
Echinococcus granulosus WD repeat containing protein 48 0.0109 0.0306 0.0341
Treponema pallidum fructose-bisphosphate aldolase 0.0531 0.1746 0.6587
Schistosoma mansoni coup transcription factor 0.004 0.0074 0.0082
Loa Loa (eye worm) hypothetical protein 0.0209 0.0647 0.1587
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0134 0.0134
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0074 0.0226
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.003
Echinococcus granulosus neuropeptide receptor 0.0119 0.034 0.0379
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.03 0.113
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0259 0.082 0.247
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0034 0.0051 0.0124
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1216 0.4077 1
Brugia malayi Hypothetical WD-repeat protein F35G12.4 in chromosome III 0.0109 0.0306 0.0751
Brugia malayi hypothetical protein 0.0119 0.034 0.0834
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0104 0.0224
Schistosoma mansoni hypothetical protein 0.0091 0.0246 0.0274
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0009 0.0009
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.029 0.0924 0.0928
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0211 0.0657 0.0732
Brugia malayi chromobox protein homolog 3 0.0049 0.0105 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0107 0.0119
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0168 0.0518
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0797 0.265 0.2664
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0028 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.0022 0.0012 0.0036
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0027
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0154 0.0666
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0023 0.0085
Toxoplasma gondii hypothetical protein 0.0034 0.0051 0.0156
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.011 0.011
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.0069 0.0077
Giardia lamblia Kinesin-5 0.0023 0.0014 0.0053
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0023 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0072 0.0153
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0079 0.0205 0.0441
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0023 0.0023
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0119 0.034 0.0731
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0126 0.0126
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0074 0.0082
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0074 0.0158
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0086 0.023 0.0256
Echinococcus granulosus tyrosine kinase 0.0034 0.0053 0.0059
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0094 0.0257 0.0923
Brugia malayi Cytochrome P450 family protein 0.0043 0.0084 0.0204
Echinococcus multilocularis jumonji domain containing protein 0.0078 0.0203 0.0226

Activities

Activity type Activity value Assay description Source Reference
GSH (binding) = 11 % Extent of reaction of the compound with 5 equiv of reduced glutathione (GSH) between 16 and 22 hours at pH 7.4 and 37 degree C ChEMBL. 2299640
GSH (binding) = 17 % Extent of reaction of the compound with 20 equiv of reduced glutathione (GSH) in 20 hours at pH 7.4 and 37 degree C ChEMBL. 2299640
I50 (binding) = 25 nM In vitro inhibition of human carbonic anhydrase II (0.1 nM). ChEMBL. 2299640
IC50 (binding) = 25 nM In vitro inhibition of human carbonic anhydrase II (0.1 nM). ChEMBL. 2299640
S = 0.08 mg ml-1 Solubility ChEMBL. 2299640

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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