Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = -1 % | Percentage inhibition for muscarinic acetylcholine receptor at concentration 10e-6 M. | ChEMBL. | 3351856 |
Inhibition (binding) | = -1 % | Percentage inhibition for muscarinic acetylcholine receptor at concentration 10e-6 M. | ChEMBL. | 3351856 |
Inhibition (binding) | = 1 % | Percentage inhibition for muscarinic acetylcholine receptor at concentration 10 e-5M. | ChEMBL. | 3351856 |
Inhibition (binding) | = 1 % | Percentage inhibition for muscarinic acetylcholine receptor at concentration 10 e-5M. | ChEMBL. | 3351856 |
Inhibition (functional) | = 7 % | Inhibtion of stress-induced ulcer formation in rats by 10 mg/kg p.o. administration. | ChEMBL. | 3351856 |
Inhibition (functional) | = 73 % | The antiulcer activity against stress-induced ulcer in rats by 30 mg/kg peroral administration. | ChEMBL. | 3351856 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.