Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0095 | 0.0398 | 0.0398 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.008 | 0 | 0.5 |
Brugia malayi | Fucosyl transferase family protein | 0.0095 | 0.0398 | 0.0398 |
Onchocerca volvulus | 0.008 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0472 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.008 | 0 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.008 | 0 | 0.5 |
Onchocerca volvulus | 0.008 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0472 | 1 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0095 | 0.0398 | 0.0398 |
Onchocerca volvulus | 0.008 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0472 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.008 | 0 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.008 | 0 | 0.5 |
Loa Loa (eye worm) | fucosyl transferase | 0.0095 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0472 | 1 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0095 | 0.0398 | 0.0398 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.008 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0472 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0398 | 0.0398 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0095 | 0.0398 | 0.0398 |
Brugia malayi | Carboxylesterase family protein | 0.0472 | 1 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.0095 | 0.0398 | 0.0398 |
Echinococcus granulosus | acetylcholinesterase | 0.0472 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0472 | 1 | 1 |
Onchocerca volvulus | 0.008 | 0 | 0.5 | |
Onchocerca volvulus | 0.008 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0472 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 1 | 1 |
Brugia malayi | alpha1,3-fucosyltransferase homologue | 0.0095 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0472 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Conversion (functional) | = 2.59 % | Cyclic AMP accumulation in Rat brain cerebral cortical slices by the compound, activity expressed as % conversion | ChEMBL. | 3001304 |
Conversion (functional) | = 2.63 % | Cyclic AMP accumulation in Rat brain cerebral cortical slices by the compound, activity expressed as % conversion | ChEMBL. | 3001304 |
Conversion (functional) | = 2.81 % | Cyclic AMP accumulation in Rat brain cerebral cortical slices by the compound, activity expressed as % conversion | ChEMBL. | 3001304 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.