Detailed information for compound 283673

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 351.278 | Formula: C18H23BrO2
  • H donors: 0 H acceptors: 2 LogP: 2.8 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CCC2(C(=C1)[C@H](Br)CC1C2CCC2C1CCC2=O)C
  • InChi: 1S/C18H23BrO2/c1-18-7-6-10(20)8-15(18)16(19)9-13-11-3-5-17(21)12(11)2-4-14(13)18/h8,11-14,16H,2-7,9H2,1H3/t11?,12?,13?,14?,16-,18?/m1/s1
  • InChiKey: DBVWYQFZUUZZQG-RYGWJARMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuroligin 3 (S09 family) 0.0035 0.0048 0.0067
Leishmania major beta tubulin 0.1464 0.3322 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0038 0.005
Brugia malayi Carboxylesterase family protein 0.0205 0.0439 0.0439
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0025 0.0076
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0198
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.116 0.2627 0.2627
Schistosoma mansoni nardilysin (M16 family) 0.0024 0.0024 0.0027
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0008 0.0003
Entamoeba histolytica adenosine deaminase, putative 0.0083 0.016 0.0461
Entamoeba histolytica hypothetical protein 0.0072 0.0135 0.0385
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Trichomonas vaginalis adenosine deaminase, putative 0.0083 0.016 0.0461
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.116 0.2627 0.3543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0024 0.0053
Brugia malayi G protein-coupled receptor F59B2.13 0.116 0.2627 0.2627
Echinococcus granulosus neuropeptide s receptor 0.116 0.2627 0.3539
Trypanosoma cruzi AMP deaminase, putative 0.0027 0.0031 0.0073
Trichomonas vaginalis tubulin epsilon chain, putative 0.1464 0.3322 1
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0038 0.0109
Brugia malayi Carboxylesterase family protein 0.0035 0.0048 0.0048
Echinococcus multilocularis BC026374 protein (S09 family) 0.0035 0.0048 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0146 0.0419
Schistosoma mansoni hypothetical protein 0.0164 0.0345 0.0542
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0172 0.0172
Echinococcus granulosus tar DNA binding protein 0.019 0.0405 0.0538
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0042 0.0066 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Trypanosoma brucei AMP deaminase, putative 0.0027 0.0031 0.0069
Echinococcus multilocularis lamin dm0 0.0027 0.0031 0.0039
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0047 0.0077 0.0095
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0038 0.0049
Brugia malayi MH2 domain containing protein 0.0025 0.0025 0.0025
Leishmania major beta tubulin 0.1464 0.3322 1
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0091 0.0255
Schistosoma mansoni cpg binding protein 0.0028 0.0033 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Onchocerca volvulus 0.116 0.2627 0.8934
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0106 0.016
Echinococcus granulosus neuropeptide receptor A26 0.116 0.2627 0.3539
Echinococcus multilocularis nardilysin 0.0024 0.0024 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0172 0.0264
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0172 0.0223
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0007
Brugia malayi Dopamine receptor 0.116 0.2627 0.2627
Schistosoma mansoni AMP deaminase 0.0027 0.0031 0.0039
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Onchocerca volvulus Adenosine deaminase homolog 0.0083 0.016 0.0521
Onchocerca volvulus 0.116 0.2627 0.8934
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Onchocerca volvulus 0.0235 0.0508 0.1708
Echinococcus granulosus neuropeptides capa receptor 0.116 0.2627 0.3539
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0027 0.0031 0.0073
Trypanosoma brucei beta tubulin 0.1464 0.3322 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0172 0.0223
Echinococcus multilocularis cpg binding protein 0.0029 0.0036 0.0046
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0083 0.016 0.0475
Echinococcus granulosus neuropeptide receptor 0.116 0.2627 0.3539
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus granulosus lysosome membrane protein 2 0.0042 0.0066 0.0079
Leishmania major pyruvate kinase 0.0033 0.0044 0.0112
Schistosoma mansoni biogenic amine receptor 0.116 0.2627 0.4203
Echinococcus multilocularis beta tubulin 0.1464 0.3322 0.4481
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Echinococcus granulosus smad 0.0025 0.0025 0.0025
Brugia malayi hypothetical protein 0.0463 0.103 0.103
Brugia malayi putative neuropeptide receptor 0.116 0.2627 0.2627
Loa Loa (eye worm) hypothetical protein 0.0451 0.1002 0.3015
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.116 0.2627 0.3543
Brugia malayi follicle stimulating hormone receptor 0.1394 0.3163 0.3163
Loa Loa (eye worm) hypothetical protein 0.0748 0.1683 0.5066
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus multilocularis fmrfamide receptor 0.116 0.2627 0.3543
Schistosoma mansoni tubulin subunit beta 0.1464 0.3322 0.5317
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni tubulin subunit beta 0.1464 0.3322 0.5317
Schistosoma mansoni nardilysin (M16 family) 0.0024 0.0024 0.0027
Echinococcus granulosus lamin dm0 0.0027 0.0031 0.0032
Onchocerca volvulus 0.116 0.2627 0.8934
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.009 0.0176 0.0507
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0048 0.0067
Plasmodium vivax adenosine deaminase, putative 0.0083 0.016 0.0461
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.116 0.2627 0.4203
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0025 0.0025
Schistosoma mansoni adenoreceptor 0.116 0.2627 0.4203
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1297 0.294 0.4704
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.116 0.2627 0.7908
Echinococcus multilocularis pyruvate kinase 0.0026 0.0028 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.116 0.2627 0.4203
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.116 0.2627 0.3539
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0008 0.0002
Onchocerca volvulus 0.116 0.2627 0.8934
Schistosoma mansoni tar DNA-binding protein 0.019 0.0405 0.0639
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Onchocerca volvulus 0.0035 0.0048 0.0141
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0048 0.0067
Giardia lamblia Beta tubulin 0.1464 0.3322 1
Loa Loa (eye worm) TYRA-2 protein 0.116 0.2627 0.7908
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.019 0.0404 0.0542
Echinococcus multilocularis musashi 0.0027 0.0031 0.0039
Schistosoma mansoni smad1 5 8 and 0.0025 0.0025 0.0029
Schistosoma mansoni hypothetical protein 0.0094 0.0185 0.0286
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0134 0.0382
Brugia malayi MH1 domain containing protein 0.0025 0.0025 0.0025
Brugia malayi Dopamine receptor protein 1 0.116 0.2627 0.2627
Giardia lamblia GTOR 0.009 0.0176 0.0508
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Brugia malayi Pre-SET motif family protein 0.003 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.116 0.2627 0.4203
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.116 0.2627 0.4203
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0198 0.0306
Echinococcus multilocularis Tubulin beta 2C chain 0.1464 0.3322 0.4481
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0443 0.1332
Schistosoma mansoni tubulin subunit beta 0.1464 0.3322 0.5317
Echinococcus multilocularis orexin receptor type 2 0.116 0.2627 0.3543
Echinococcus multilocularis neuropeptides capa receptor 0.116 0.2627 0.3543
Echinococcus granulosus thyrotropin releasing hormone receptor 0.116 0.2627 0.3539
Loa Loa (eye worm) hypothetical protein 0.0083 0.016 0.0481
Brugia malayi intermediate filament protein 0.0027 0.0031 0.0031
Treponema pallidum adenosine deaminase 0.0083 0.016 0.5
Brugia malayi G-protein coupled receptor 0.116 0.2627 0.2627
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0007 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0038 0.005
Echinococcus granulosus g-protein coupled receptor 0.116 0.2627 0.3539
Echinococcus multilocularis acetylcholinesterase 0.0205 0.0439 0.059
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0135 0.0205
Plasmodium vivax SET domain protein, putative 0.003 0.0038 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Schistosoma mansoni pyruvate kinase 0.0033 0.0044 0.0059
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0027 0.0031 0.0073
Schistosoma mansoni neuropeptide F-like receptor 0.116 0.2627 0.4203
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.116 0.2627 0.3539
Echinococcus multilocularis Protein lozenge 0.0057 0.0098 0.013
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0035 0.0048 0.0382
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0038 0.005
Echinococcus granulosus tubulin subunit beta 0.1464 0.3322 0.4478
Schistosoma mansoni cpg binding protein 0.0029 0.0036 0.0047
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0083 0.016 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Trypanosoma cruzi AMP deaminase 2, putative 0.0027 0.0031 0.0073
Echinococcus granulosus beta tubulin 0.1464 0.3322 0.4478
Echinococcus granulosus AMP deaminase 2 0.0027 0.0031 0.0033
Brugia malayi Latrophilin receptor protein 2 0.019 0.0404 0.0404
Brugia malayi Carboxylesterase family protein 0.0205 0.0439 0.0439
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0092 0.0271
Echinococcus granulosus microtubule associated protein 2 0.2738 0.6242 0.8421
Onchocerca volvulus 0.0027 0.0031 0.0081
Brugia malayi hypothetical protein 0.0035 0.0048 0.0048
Echinococcus multilocularis para nitrobenzyl esterase 0.0035 0.0048 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Echinococcus granulosus Tubulin beta 2C chain 0.1464 0.3322 0.4478
Schistosoma mansoni cpg binding protein 0.0029 0.0036 0.0047
Loa Loa (eye worm) hypothetical protein 0.01 0.0198 0.0595
Leishmania major beta tubulin 0.1464 0.3322 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0067 0.0123 0.0364
Schistosoma mansoni tar DNA-binding protein 0.019 0.0405 0.0639
Brugia malayi AKH receptor 0.116 0.2627 0.2627
Schistosoma mansoni lamin 0.0027 0.0031 0.0038
Plasmodium vivax adenosine/AMP deaminase, putative 0.0027 0.0031 0.0073
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0027 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.0451 0.1002 0.3015
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0066 0.0086
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0338 0.0744 0.1001
Loa Loa (eye worm) carboxylesterase 0.0035 0.0048 0.0146
Trypanosoma cruzi AMP deaminase, putative 0.0027 0.0031 0.0073
Echinococcus multilocularis tubulin subunit beta 0.1464 0.3322 0.4481
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0038 0.0095
Echinococcus granulosus dnaJ subfamily B 0.0396 0.0876 0.1174
Echinococcus multilocularis tachykinin peptides receptor 99D 0.116 0.2627 0.3543
Echinococcus granulosus alpha 1A adrenergic receptor 0.116 0.2627 0.3539
Loa Loa (eye worm) runx1 0.0057 0.0098 0.0296
Loa Loa (eye worm) hypothetical protein 0.0056 0.0098 0.0294
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0114 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0223
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Loa Loa (eye worm) RNA binding protein 0.019 0.0405 0.1219
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0198
Schistosoma mansoni BC026374 protein (S09 family) 0.0035 0.0048 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0038 0.0095
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0044 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0008 0.0003
Echinococcus granulosus Smad4 0.0025 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Mycobacterium ulcerans carboxylesterase, LipT 0.0035 0.0048 0.0079
Echinococcus granulosus tm gpcr rhodopsin 0.116 0.2627 0.3539
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) carboxylesterase 0.0205 0.0439 0.1323
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0748 0.1683 0.1683
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0223
Loa Loa (eye worm) latrophilin receptor protein 2 0.019 0.0404 0.1215
Schistosoma mansoni hypothetical protein 0.0072 0.0135 0.0205
Trichomonas vaginalis tubulin, putative 0.1464 0.3322 1
Leishmania major cathepsin L-like protease 0.0063 0.0114 0.0322
Brugia malayi hypothetical protein 0.0072 0.0135 0.0135
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0135 0.0179
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0066 0.0086
Echinococcus multilocularis Tubulin beta 2C chain 0.1464 0.3322 0.4481
Loa Loa (eye worm) Smad1 0.0025 0.0025 0.0076
Echinococcus granulosus 3'partial|nardilysin 0.0024 0.0024 0.0023
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Schistosoma mansoni amine GPCR 0.116 0.2627 0.4203
Schistosoma mansoni hypothetical protein 0.0164 0.0345 0.0542
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Brugia malayi Tubulin beta-1 chain 0.1464 0.3322 0.3322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0222
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0008 0.0002
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.116 0.2627 0.3543
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0066 0.0086
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0031 0.0092
Schistosoma mansoni CD36-like class B scavenger receptor 0.0042 0.0066 0.0094
Trypanosoma cruzi AMP deaminase, putative 0.0027 0.0031 0.0073
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0027 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Onchocerca volvulus 0.0035 0.0048 0.0141
Schistosoma mansoni opsin-like receptor 0.116 0.2627 0.4203
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0035 0.0048 0.0125
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.009 0.0176 0.0228
Schistosoma mansoni myosin xvIII 0.116 0.2627 0.4203
Schistosoma mansoni alpha-1 adrenergic receptor 0.116 0.2627 0.4203
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0044 0.0112
Echinococcus granulosus carboxylesterase 5A 0.0205 0.0439 0.0584
Echinococcus granulosus tm gpcr rhodopsin 0.116 0.2627 0.3539
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0338 0.0744 0.0995
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0198
Onchocerca volvulus 0.116 0.2627 0.8934
Trypanosoma brucei peptidase, putative 0.0024 0.0024 0.0047
Echinococcus granulosus pyruvate kinase 0.0017 0.0007 0.0001
Echinococcus granulosus tumor protein p63 0.0682 0.1532 0.206
Echinococcus multilocularis pyruvate kinase 0.0033 0.0044 0.0057
Echinococcus multilocularis g protein coupled receptor 0.116 0.2627 0.3543
Trypanosoma brucei AMP deaminase, putative 0.0027 0.0031 0.0069
Echinococcus granulosus peptide allatostatin:somatostatin 0.116 0.2627 0.3539
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni amine GPCR 0.116 0.2627 0.4203
Trypanosoma cruzi AMP deaminase, putative 0.0027 0.0031 0.0073
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0044 0.0112
Echinococcus multilocularis serotonin receptor 0.116 0.2627 0.3543
Schistosoma mansoni hypothetical protein 0.0311 0.0682 0.1082
Echinococcus multilocularis Tubulin beta 2C chain 0.1464 0.3322 0.4481
Onchocerca volvulus 0.0027 0.0031 0.0081
Brugia malayi CXXC zinc finger family protein 0.0028 0.0033 0.0033
Echinococcus multilocularis g-protein coupled receptor 0.116 0.2627 0.3543
Loa Loa (eye worm) carboxylesterase 0.0035 0.0048 0.0146
Toxoplasma gondii aspartyl protease ASP1 0.0047 0.0077 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0222
Brugia malayi gonadotropin-releasing hormone receptor 2 0.116 0.2627 0.2627
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0198
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0038 0.0095
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0066 0.0086
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0013 0.0032
Echinococcus multilocularis somatostatin receptor 0.116 0.2627 0.3543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Echinococcus multilocularis sodium channel protein 0.0038 0.0055 0.0071
Brugia malayi adenosine monophosphate deaminase 0.0027 0.0031 0.0031
Leishmania major beta tubulin 0.1464 0.3322 1
Onchocerca volvulus 0.116 0.2627 0.8934
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0017 0.0008 0.0002
Brugia malayi RNA binding protein 0.019 0.0405 0.0405
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0047 0.0077 0.0232
Schistosoma mansoni biogenic amine (dopamine) receptor 0.116 0.2627 0.4203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni tubulin subunit beta 0.1464 0.3322 0.5317
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni microtubule-associated protein tau 0.2738 0.6242 1
Echinococcus multilocularis beta tubulin 0.1464 0.3322 0.4481
Echinococcus multilocularis pyruvate kinase 0.0017 0.0007 0.0007
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Onchocerca volvulus 0.0035 0.0048 0.0141
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0017 0.0008 0.0008
Echinococcus multilocularis insulin degrading enzyme 0.0024 0.0024 0.0029
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0035 0.0048 0.0382
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Brugia malayi Serotonin receptor 0.116 0.2627 0.2627
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus granulosus adenosine deaminase 0.0083 0.016 0.0206
Loa Loa (eye worm) hypothetical protein 0.0463 0.103 0.3101
Brugia malayi beta-tubulin, identical 0.1464 0.3322 0.3322
Loa Loa (eye worm) hypothetical protein 0.003 0.0038 0.0115
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0066 0.0079
Echinococcus granulosus g protein coupled receptor 0.116 0.2627 0.3539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0223
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.0794 0.2391
Plasmodium falciparum pyruvate kinase 0.0033 0.0044 0.0112
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.116 0.2627 0.4203
Loa Loa (eye worm) hypothetical protein 0.0047 0.0077 0.0232
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.0794 0.2391
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0176 0.051
Leishmania major beta tubulin 0.1464 0.3322 1
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.009 0.0176 0.0235
Leishmania major beta tubulin 0.1464 0.3322 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0114 0.0322
Entamoeba histolytica hypothetical protein 0.0072 0.0135 0.0385
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0007 0.0002
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0083 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0038 0.0095
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.009 0.0176 0.051
Mycobacterium tuberculosis Carboxylesterase LipT 0.0035 0.0048 0.0382
Trypanosoma brucei RNA helicase, putative 0.0311 0.0682 0.2033
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0176 0.051
Brugia malayi G-protein coupled receptor 0.116 0.2627 0.2627
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Brugia malayi G protein-coupled receptor 0.116 0.2627 0.2627
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0008 0.0003
Schistosoma mansoni hypothetical protein 0.116 0.2627 0.4203
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0044 0.0044
Trypanosoma cruzi peptidase, putative 0.0024 0.0024 0.005
Echinococcus granulosus acetylcholinesterase 0.0205 0.0439 0.0584
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0066 0.0079
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.116 0.2627 0.4203
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0064
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0025 0.0031
Schistosoma mansoni survival motor neuron protein 0.0094 0.0185 0.0286
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.116 0.2627 0.3543
Loa Loa (eye worm) G-protein coupled receptor 0.116 0.2627 0.7908
Schistosoma mansoni adenosine deaminase-related 0.0083 0.016 0.0245
Leishmania major phosphoglycan beta 1,3 galactosyltransferase 5 0.0024 0.0024 0.005
Schistosoma mansoni growth hormone secretagogue receptor 0.116 0.2627 0.4203
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0114 0.0322
Echinococcus multilocularis biogenic amine (5HT) receptor 0.116 0.2627 0.3543
Schistosoma mansoni neuropeptide receptor 0.116 0.2627 0.4203
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.116 0.2627 0.3543
Trichomonas vaginalis tubulin epsilon chain, putative 0.1464 0.3322 1
Brugia malayi hypothetical protein 0.0451 0.1002 0.1002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0222
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0044 0.0132
Onchocerca volvulus 0.1297 0.294 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Echinococcus granulosus Tubulin beta 2C chain 0.1464 0.3322 0.4478
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0044 0.0044
Brugia malayi neuropeptide F receptor 0.116 0.2627 0.2627
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0002 0.0006
Echinococcus multilocularis neuropeptide receptor 0.116 0.2627 0.3543
Echinococcus granulosus biogenic amine 5HT receptor 0.116 0.2627 0.3539
Echinococcus multilocularis neuropeptide Y receptor 0.116 0.2627 0.3543
Mycobacterium ulcerans glutaminase 0.0278 0.0606 1
Schistosoma mansoni tubulin subunit beta 0.1464 0.3322 0.5317
Echinococcus multilocularis pyruvate kinase 0.0017 0.0007 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.116 0.2627 0.3539
Leishmania major beta tubulin 0.1464 0.3322 1
Schistosoma mansoni neuropeptide receptor 0.116 0.2627 0.4203
Brugia malayi neuropeptide F receptor 0.116 0.2627 0.2627
Schistosoma mansoni smad 0.0025 0.0025 0.0029
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0055 0.0141
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.116 0.2627 0.8934
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0038 0.0042
Echinococcus multilocularis Tubulin beta 2C chain 0.1464 0.3322 0.4481
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0038 0.0095
Brugia malayi Adenosine/AMP deaminase family protein 0.0083 0.016 0.016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0038 0.005
Schistosoma mansoni neuropeptide f receptor 76f 0.116 0.2627 0.4203
Onchocerca volvulus 0.01 0.0198 0.0651
Echinococcus multilocularis tubulin beta 1 chain 0.1464 0.3322 0.4481
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0198
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Plasmodium falciparum adenosine deaminase 0.0083 0.016 0.0461
Entamoeba histolytica hypothetical protein 0.0072 0.0135 0.0385
Loa Loa (eye worm) ctsf protein 0.0017 0.0007 0.0021
Toxoplasma gondii insulysin, putative 0.0023 0.0021 0.0057
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.116 0.2627 0.3543
Schistosoma mansoni biogenic amine receptor 0.116 0.2627 0.4203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Trichomonas vaginalis tubulin gamma chain, putative 0.1464 0.3322 1
Echinococcus granulosus orexin receptor type 2 0.116 0.2627 0.3539
Loa Loa (eye worm) hypothetical protein 0.0205 0.0439 0.1323
Brugia malayi Calcitonin receptor-like protein seb-1 0.06 0.1343 0.1343
Echinococcus multilocularis g protein coupled receptor 0.116 0.2627 0.3543
Brugia malayi MH1 domain containing protein 0.0025 0.0025 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Brugia malayi MH2 domain containing protein 0.0025 0.0025 0.0025
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Echinococcus multilocularis g protein coupled receptor 0.116 0.2627 0.3543
Plasmodium falciparum plasmepsin VI 0.0047 0.0077 0.0212
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0038 0.0115
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.019 0.0404 0.0536
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0024
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0042 0.0066 0.0094
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Leishmania major beta tubulin 0.1464 0.3322 1
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0508 0.1511
Mycobacterium ulcerans adenosine deaminase 0.0083 0.016 0.2059
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Brugia malayi Smad1 0.0025 0.0025 0.0025
Onchocerca volvulus 0.116 0.2627 0.8934
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0066 0.0079
Brugia malayi TAR-binding protein 0.019 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3248 0.7411 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Plasmodium vivax plasmepsin IV, putative 0.0047 0.0077 0.0212
Echinococcus granulosus tachykinin peptides receptor 99D 0.116 0.2627 0.3539
Brugia malayi Melatonin receptor type 1A 0.116 0.2627 0.2627
Schistosoma mansoni lamin 0.0027 0.0031 0.0038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.116 0.2627 0.2627
Schistosoma mansoni amine GPCR 0.116 0.2627 0.4203
Brugia malayi Tachykinin-like peptides receptor 99D 0.116 0.2627 0.2627
Toxoplasma gondii AMP deaminase 0.0027 0.0031 0.0088
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Entamoeba histolytica AMP deaminase, putative 0.0027 0.0031 0.0073
Onchocerca volvulus Neuropeptide F receptor homolog 0.116 0.2627 0.8934
Echinococcus multilocularis survival motor neuron protein 1 0.0463 0.103 0.1388
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Echinococcus granulosus serotonin receptor 0.116 0.2627 0.3539
Giardia lamblia Pyruvate kinase 0.0033 0.0044 0.011
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0017 0.0008 0.0003
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0044 0.0108
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0008 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.009 0.0176 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0134 0.0382
Echinococcus granulosus tubulin beta 1 chain 0.1464 0.3322 0.4478
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Echinococcus granulosus neuropeptides capa receptor 0.116 0.2627 0.3539
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0024 0.0024 0.0027
Echinococcus multilocularis serotonin receptor 0.116 0.2627 0.3543
Leishmania major beta tubulin 0.1464 0.3322 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.019 0.0405 0.1219
Brugia malayi Pre-SET motif family protein 0.0207 0.0443 0.0443
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0044 0.0112
Echinococcus multilocularis neuropeptide Y receptor 0.116 0.2627 0.3543
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0172 0.0229
Echinococcus granulosus sodium channel protein 0.0038 0.0055 0.0065
Schistosoma mansoni biogenic amine (5HT) receptor 0.116 0.2627 0.4203
Echinococcus granulosus g protein coupled receptor 0.116 0.2627 0.3539
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0083 0.016 1
Toxoplasma gondii beta-1 tubulin, putative 0.1464 0.3322 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0094
Plasmodium vivax aspartyl proteinase, putative 0.0047 0.0077 0.0212
Echinococcus multilocularis pyruvate kinase 0.0033 0.0044 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Giardia lamblia Beta tubulin 0.1464 0.3322 1
Brugia malayi putative neuropeptide receptor NPR1 0.116 0.2627 0.2627
Echinococcus granulosus GPCR family 2 0.019 0.0404 0.0536
Entamoeba histolytica hypothetical protein 0.0072 0.0135 0.0385
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0072 0.0134 0.0383
Echinococcus granulosus neuropeptide FF receptor 2 0.116 0.2627 0.3539
Onchocerca volvulus 0.116 0.2627 0.8934
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus multilocularis microtubule associated protein 2 0.2738 0.6242 0.8422
Echinococcus granulosus hypothetical protein 0.116 0.2627 0.3539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Onchocerca volvulus 0.116 0.2627 0.8934
Echinococcus granulosus neuropeptide Y receptor 0.116 0.2627 0.3539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0134 0.0382
Toxoplasma gondii sporozoite developmental protein 0.0024 0.0024 0.0065
Trypanosoma cruzi target of rapamycin kinase 3 0.0072 0.0134 0.0383
Schistosoma mansoni biogenic amine (dopamine) receptor 0.116 0.2627 0.4203
Schistosoma mansoni hypothetical protein 0.019 0.0404 0.0636
Echinococcus granulosus BC026374 protein S09 family 0.0035 0.0048 0.0056
Echinococcus multilocularis tar DNA binding protein 0.019 0.0405 0.0544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0093 0.0259
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.116 0.2627 0.7908
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0007 0.0016
Brugia malayi sulfakinin receptor protein 0.1372 0.3111 0.3111
Loa Loa (eye worm) BEN-1 protein 0.1464 0.3322 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1394 0.3163 0.9523
Echinococcus multilocularis neuropeptide FF receptor 2 0.116 0.2627 0.3543
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.116 0.2627 0.7908
Onchocerca volvulus 0.0028 0.0033 0.0088
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0035 0.0048 0.0063
Schistosoma mansoni cathepsin D (A01 family) 0.0139 0.0288 0.0451
Echinococcus granulosus sex peptide receptor 0.116 0.2627 0.3539
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0047 0.0077 0.0226
Entamoeba histolytica AMP deaminase, putative 0.0027 0.0031 0.0073
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0044 0.0126
Schistosoma mansoni biogenic amine receptor 0.116 0.2627 0.4203
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0172 0.0229
Trypanosoma brucei AMP deaminase, putative 0.0027 0.0031 0.0069
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.009 0.0176 0.051
Echinococcus granulosus pyruvate kinase 0.0033 0.0044 0.005
Schistosoma mansoni smad1 5 8 and 0.0025 0.0025 0.0029
Echinococcus multilocularis smad 0.0025 0.0025 0.0031
Schistosoma mansoni histamine h1 receptor 0.116 0.2627 0.4203
Echinococcus granulosus tubulin beta 4A class IVa 0.1464 0.3322 0.4478
Echinococcus granulosus insulin degrading enzyme 0.0024 0.0024 0.0023
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0025 0.0031
Loa Loa (eye worm) neuropeptide F receptor 0.116 0.2627 0.7908
Leishmania major beta tubulin 0.1464 0.3322 1
Entamoeba histolytica tubulin family protein 0.1464 0.3322 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0031 0.0031
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1464 0.3322 0.4481
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0172 0.0517
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0038 0.0095
Trichomonas vaginalis tubulin beta chain, putative 0.1464 0.3322 1
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0008 0.0018
Loa Loa (eye worm) tubulin beta chain 0.1464 0.3322 1
Schistosoma mansoni hypothetical protein 0.116 0.2627 0.4203
Trypanosoma cruzi AMP deaminase, putative 0.0027 0.0031 0.0073
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0072 0.0134 0.0379
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.116 0.2627 0.4203
Leishmania major beta tubulin 0.1464 0.3322 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Echinococcus granulosus neuropeptide receptor 0.1309 0.2967 0.3999
Schistosoma mansoni biogenic amine (5HT) receptor 0.116 0.2627 0.4203
Echinococcus granulosus fmrfamide receptor 0.116 0.2627 0.3539
Echinococcus granulosus geminin 0.0164 0.0345 0.0456
Echinococcus multilocularis AMP deaminase 2 0.0027 0.0031 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.116 0.2627 0.3543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Schistosoma mansoni opsin-like receptor 0.116 0.2627 0.4203
Brugia malayi Carboxylesterase family protein 0.0035 0.0048 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Leishmania major beta tubulin 0.1464 0.3322 1
Onchocerca volvulus 0.116 0.2627 0.8934
Brugia malayi RE15519p 0.116 0.2627 0.2627
Leishmania major beta tubulin 0.1464 0.3322 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0038 0.005
Plasmodium falciparum plasmepsin I 0.0047 0.0077 0.0212
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0205 0.0439 0.0694
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Brugia malayi Serotonin receptor 0.116 0.2627 0.2627
Brugia malayi hypothetical protein 0.0042 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0176 0.051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0108 0.0304
Brugia malayi ORL1-like opioid receptor 0.116 0.2627 0.2627
Schistosoma mansoni tar DNA-binding protein 0.019 0.0405 0.0639
Brugia malayi Carboxylesterase family protein 0.0035 0.0048 0.0048
Brugia malayi Carboxylesterase family protein 0.0035 0.0048 0.0048
Loa Loa (eye worm) G-protein coupled receptor 0.116 0.2627 0.7908
Loa Loa (eye worm) glutaminase 2 0.0278 0.0606 0.1825
Echinococcus multilocularis G-protein coupled receptor, putative 0.116 0.2627 0.3543
Echinococcus multilocularis allatostatin A receptor 0.1297 0.294 0.3965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.116 0.2627 0.7908
Schistosoma mansoni acetylcholinesterase 0.0035 0.0048 0.0067
Echinococcus granulosus nardilysin 0.0024 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni cathepsin D (A01 family) 0.0139 0.0288 0.0451
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0185 0.0185
Leishmania major beta tubulin 0.1464 0.3322 1
Echinococcus multilocularis carboxylesterase 5A 0.0205 0.0439 0.059
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0038
Echinococcus multilocularis Tubulin beta 2C chain 0.1464 0.3322 0.4481
Onchocerca volvulus 0.116 0.2627 0.8934
Schistosoma mansoni amine GPCR 0.116 0.2627 0.4203
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0089
Loa Loa (eye worm) hypothetical protein 0.1372 0.3111 0.9366
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0007
Onchocerca volvulus 0.116 0.2627 0.8934
Leishmania major beta tubulin 0.1464 0.3322 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0093 0.0259
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0047 0.0077 0.0113
Echinococcus granulosus G protein coupled receptor 139 0.116 0.2627 0.3539
Loa Loa (eye worm) neuropeptide F receptor 0.116 0.2627 0.7908
Echinococcus multilocularis neuroligin 0.0035 0.0048 0.0063
Entamoeba histolytica hypothetical protein 0.0017 0.0008 0.0003
Schistosoma mansoni hypothetical protein 0.019 0.0404 0.0636
Schistosoma mansoni neuropeptide receptor 0.116 0.2627 0.4203
Brugia malayi CD36 family protein 0.0042 0.0066 0.0066
Echinococcus multilocularis tumor protein p63 0.0682 0.1532 0.2065
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Brugia malayi hypothetical protein 0.1372 0.3111 0.3111
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0083 0.016 0.0475
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0021 0.0064
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.116 0.2627 0.3543
Echinococcus granulosus Tubulin beta 2C chain 0.1464 0.3322 0.4478
Onchocerca volvulus 0.116 0.2627 0.8934
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni CD36-like class B scavenger receptor 0.0042 0.0066 0.0094
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0044 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0038 0.0095
Loa Loa (eye worm) cysteine protease 0.0017 0.0007 0.0021
Trichomonas vaginalis tubulin alpha chain, putative 0.1464 0.3322 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0038 0.0091
Echinococcus granulosus survival motor neuron protein 1 0.0463 0.103 0.1382
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0172 0.0264
Echinococcus multilocularis neuropeptides capa receptor 0.116 0.2627 0.3543
Loa Loa (eye worm) hypothetical protein 0.019 0.0404 0.1215
Loa Loa (eye worm) hypothetical protein 0.1297 0.294 0.885
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Schistosoma mansoni pyruvate kinase 0.0017 0.0007 0.0001
Echinococcus multilocularis dro:myosuppressin receptor 0.116 0.2627 0.3543
Leishmania major pyruvate kinase 0.0033 0.0044 0.0112
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0048 0.0067
Echinococcus granulosus Tubulin beta 2C chain 0.1464 0.3322 0.4478
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Schistosoma mansoni adenosine deaminase 0.0083 0.016 0.0245
Echinococcus multilocularis acetylcholinesterase 0.0205 0.0439 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0134 0.0382
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.116 0.2627 0.4203
Echinococcus multilocularis fmrfamide receptor 0.116 0.2627 0.3543
Echinococcus granulosus Tubulin beta 2C chain 0.1464 0.3322 0.4478
Echinococcus granulosus pyruvate kinase 0.0033 0.0044 0.005
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) tubulin beta-1 chain 0.1464 0.3322 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.009 0.0176 0.051
Echinococcus granulosus neuroligin 0.0035 0.0048 0.0056
Schistosoma mansoni gliotactin 0.0035 0.0048 0.0067
Toxoplasma gondii rhoptry metalloprotease toxolysin TLN1 0.0024 0.0024 0.0065
Echinococcus multilocularis neuropeptide receptor A26 0.116 0.2627 0.3543
Toxoplasma gondii beta tubulin 0.1464 0.3322 1
Loa Loa (eye worm) glutaminase 0.0278 0.0606 0.1825
Brugia malayi latrophilin 2 splice variant baaae 0.041 0.0908 0.0908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Loa Loa (eye worm) TAR-binding protein 0.019 0.0405 0.1219
Echinococcus multilocularis Smad4 0.0025 0.0025 0.0031
Onchocerca volvulus 0.116 0.2627 0.8934
Schistosoma mansoni opsin-like receptor 0.116 0.2627 0.4203
Schistosoma mansoni intermediate filament proteins 0.0027 0.0031 0.0038
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0067 0.0177
Brugia malayi insulin-degrading enzyme 0.0024 0.0024 0.0024
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0035 0.0048 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0134 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0123 0.035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Trypanosoma cruzi peptidase, putative 0.0024 0.0024 0.005
Echinococcus granulosus somatostatin receptor 0.116 0.2627 0.3539
Plasmodium vivax tubulin beta chain, putative 0.1464 0.3322 1
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0038 0.0055 0.0145
Echinococcus granulosus neuropeptide Y receptor 0.116 0.2627 0.3539
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0047 0.0077 0.0101
Plasmodium falciparum tubulin beta chain 0.1464 0.3322 1
Echinococcus granulosus pyruvate kinase 0.0017 0.0007 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0038 0.0038
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.116 0.2627 0.3539
Echinococcus multilocularis lysosome membrane protein 2 0.0042 0.0066 0.0086
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0025 0.0076
Leishmania major adenine aminohydrolase 0.0083 0.016 0.0461
Loa Loa (eye worm) acetylcholinesterase 1 0.0205 0.0439 0.1323
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.116 0.2627 0.3539
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0031 0.0092
Schistosoma mansoni amine GPCR 0.116 0.2627 0.4203
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0114 0.0322
Echinococcus multilocularis adenosine deaminase 0.0083 0.016 0.0213
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0034 0.0037
Schistosoma mansoni hypothetical protein 0.0396 0.0876 0.1394
Echinococcus multilocularis rhodopsin orphan GPCR 0.116 0.2627 0.3543
Leishmania major cathepsin L-like protease 0.0063 0.0114 0.0322
Echinococcus multilocularis G protein coupled receptor 139 0.1309 0.2967 0.4003
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0101 0.0284
Leishmania major beta tubulin 0.1464 0.3322 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.06 0.1343 0.4042
Trypanosoma brucei beta tubulin 0.1464 0.3322 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0035 0.0048 0.0125
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.116 0.2627 0.4203
Onchocerca volvulus 0.0035 0.0048 0.0141
Onchocerca volvulus 0.0094 0.0185 0.0608
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0044 0.0126
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0114 0.0319
Onchocerca volvulus 0.0027 0.0031 0.0082
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Entamoeba histolytica tubulin family protein 0.1464 0.3322 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0044 0.0112
Schistosoma mansoni tubulin subunit beta 0.1464 0.3322 0.5317
Schistosoma mansoni tar DNA-binding protein 0.019 0.0405 0.0639
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0066 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.116 0.2627 0.4203
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0044 0.0126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0172 0.0264
Onchocerca volvulus AMP deaminase 2 homolog 0.0027 0.0031 0.0082
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0176 0.053
Onchocerca volvulus 0.0451 0.1002 0.3391
Echinococcus granulosus g protein coupled receptor 0.116 0.2627 0.3539
Loa Loa (eye worm) beta-tubulin 0.1464 0.3322 1
Leishmania major beta tubulin 0.1464 0.3322 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0081 0.0223
Loa Loa (eye worm) hypothetical protein 0.0056 0.0098 0.0294
Brugia malayi MH2 domain containing protein 0.036 0.0794 0.0794
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0066 0.0086
Plasmodium falciparum plasmepsin IV 0.0047 0.0077 0.0212
Echinococcus multilocularis neuropeptide s receptor 0.116 0.2627 0.3543
Leishmania major AMP deaminase, putative 0.0027 0.0031 0.0073
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.116 0.2627 0.3543
Loa Loa (eye worm) fibroinase 0.0017 0.0007 0.0021
Schistosoma mansoni pyruvate kinase 0.0033 0.0044 0.0059
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.019 0.0404 0.0404
Brugia malayi hypothetical protein 0.116 0.2627 0.2627
Schistosoma mansoni neuropeptide receptor 0.1309 0.2967 0.4749
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0132
Echinococcus granulosus lamin 0.0027 0.0031 0.0032
Onchocerca volvulus 0.116 0.2627 0.8934
Loa Loa (eye worm) AMP deaminase 0.0027 0.0031 0.0094
Loa Loa (eye worm) hypothetical protein 0.041 0.0908 0.2733
Echinococcus granulosus cpg binding protein 0.0029 0.0036 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0038 0.0095
Echinococcus granulosus pyruvate kinase 0.0017 0.0007 0.0001
Onchocerca volvulus 0.116 0.2627 0.8934
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.116 0.2627 0.3539
Echinococcus granulosus rhodopsin orphan GPCR 0.116 0.2627 0.3539
Echinococcus granulosus beta tubulin 0.1464 0.3322 0.4478
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0044 0.0126
Echinococcus multilocularis nardilysin 0.0024 0.0024 0.0029
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.009 0.0176 0.0507
Leishmania major cathepsin L-like protease 0.0063 0.0114 0.0322
Toxoplasma gondii beta-tubulin, putative 0.1464 0.3322 1
Brugia malayi larval opioid receptor 0.116 0.2627 0.2627
Echinococcus multilocularis alpha 1A adrenergic receptor 0.116 0.2627 0.3543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0103 0.0291
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0092
Echinococcus multilocularis neuropeptide receptor 0.1309 0.2967 0.4003
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0038 0.0095
Echinococcus multilocularis sex peptide receptor 0.116 0.2627 0.3543
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.009 0.0176 0.051
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0033 0.0098
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.116 0.2627 0.4203
Echinococcus granulosus 7tm_1 domain containing protein 0.116 0.2627 0.3539
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0038 0.0055 0.0065
Schistosoma mansoni hypothetical protein 0.116 0.2627 0.4203
Brugia malayi hypothetical protein 0.0042 0.0066 0.0066
Echinococcus granulosus 7TM GPCR rhodopsin 0.116 0.2627 0.3539
Echinococcus granulosus para nitrobenzyl esterase 0.0035 0.0048 0.0056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.116 0.2627 0.4203
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Brugia malayi Serotonin/octopamine receptor family protein 7 0.116 0.2627 0.2627
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0027 0.0031 0.0073
Echinococcus multilocularis pyruvate kinase 0.0017 0.0007 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.116 0.2627 0.2627
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.009 0.0176 0.0271
Plasmodium falciparum AMP deaminase, putative 0.0027 0.0031 0.0073
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0038 0.0049
Entamoeba histolytica adenosine deaminase, putative 0.0083 0.016 0.0461
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0044 0.0132
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0047 0.0077 0.0212
Trypanosoma cruzi beta tubulin, putative 0.1464 0.3322 1
Schistosoma mansoni Smad4 0.0025 0.0025 0.0029
Brugia malayi RNA recognition motif domain containing protein 0.019 0.0405 0.0405
Schistosoma mansoni smad1 5 8 and 0.0025 0.0025 0.0029
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0024 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0205 0.0439 0.1323
Trichomonas vaginalis glutaminase, putative 0.0278 0.0606 0.1808
Trypanosoma brucei beta tubulin 0.1464 0.3322 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0198
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0007
Echinococcus multilocularis geminin 0.0164 0.0345 0.0462
Brugia malayi Dopamine receptor protein 2 0.116 0.2627 0.2627
Trypanosoma brucei beta tubulin 0.1464 0.3322 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.116 0.2627 0.7908
Loa Loa (eye worm) insulin-degrading enzyme 0.0024 0.0024 0.0071
Loa Loa (eye worm) hypothetical protein 0.0056 0.0098 0.0294
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.116 0.2627 0.3543
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0038 0.0091
Onchocerca volvulus 0.003 0.0038 0.0106
Loa Loa (eye worm) tubulin beta-4 chain 0.1464 0.3322 1
Entamoeba histolytica protein kinase rad3, putative 0.0017 0.0008 0.0003
Toxoplasma gondii cathepsin CPL 0.0017 0.0007 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.116 0.2627 0.4203
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0146
Schistosoma mansoni hypothetical protein 0.019 0.0404 0.0636
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0038 0.0042
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0027 0.0031 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0093 0.0259
Echinococcus granulosus dro:myosuppressin receptor 0.116 0.2627 0.3539
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0007 0.0021
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0021 0.0043
Echinococcus multilocularis GPCR, family 2 0.019 0.0404 0.0542
Schistosoma mansoni lozenge 0.0057 0.0098 0.0147
Schistosoma mansoni cd36 antigen 0.0042 0.0066 0.0094
Schistosoma mansoni hypothetical protein 0.019 0.0404 0.0636
Echinococcus granulosus intermediate filament protein 0.0027 0.0031 0.0032
Echinococcus multilocularis lamin 0.0027 0.0031 0.0039
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0007
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.0876 0.118
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0025 0.0029
Plasmodium falciparum plasmepsin II 0.0047 0.0077 0.0212
Leishmania major beta tubulin 0.1464 0.3322 1
Schistosoma mansoni hypothetical protein 0.041 0.0908 0.1445
Chlamydia trachomatis pyruvate kinase 0.0033 0.0044 1
Giardia lamblia Beta tubulin 0.1464 0.3322 1
Schistosoma mansoni glutaminase 0.0278 0.0606 0.0961
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0007 0.0007
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0044 0.0108
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0066 0.0079
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0007
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0007
Echinococcus granulosus acetylcholinesterase 0.0205 0.0439 0.0584
Loa Loa (eye worm) tubulin beta-2A chain 0.1464 0.3322 1
Loa Loa (eye worm) BEN-1 protein 0.1464 0.3322 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0135 0.0173
Echinococcus granulosus allatostatin A receptor 0.1297 0.294 0.3961
Loa Loa (eye worm) melatonin receptor type 1A 0.116 0.2627 0.7908
Echinococcus granulosus tm gpcr rhodopsin 0.3248 0.7411 1
Leishmania major hypothetical protein, conserved 0.0027 0.0031 0.0073
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.009 0.0176 0.051
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.009 0.0176 0.051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0091 0.0255
Schistosoma mansoni tar DNA-binding protein 0.019 0.0405 0.0639
Onchocerca volvulus 0.0035 0.0048 0.0141
Loa Loa (eye worm) hypothetical protein 0.0056 0.0098 0.0294
Brugia malayi glutaminase DH11.1 0.0278 0.0606 0.0606
Trichomonas vaginalis adenosine deaminase, putative 0.0083 0.016 0.0461

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 62 % Percent inhibition of human placental Cytochrome P450 19A1 at 3:1 inhibitor: androstenedione (0.7 uM) ratio ChEMBL. 4009601
Inhibition (binding) = 62 % Percent inhibition of human placental Cytochrome P450 19A1 at 3:1 inhibitor: androstenedione (0.7 uM) ratio ChEMBL. 4009601

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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