Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Aldose reductase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | TAR-binding protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Echinococcus granulosus | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Giardia lamblia | Aldose reductase | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Toxoplasma gondii | aldose reductase, putative | 0.0038 | 0.2247 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0038 | 0.2247 | 0.5 |
Onchocerca volvulus | 0.0038 | 0.2247 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Entamoeba histolytica | aldose reductase, putative | 0.0038 | 0.2247 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Trypanosoma brucei | prostaglandin f synthase | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Onchocerca volvulus | 0.0038 | 0.2247 | 0.5 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0038 | 0.2247 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0038 | 0.2247 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0038 | 0.2247 | 0.2247 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Onchocerca volvulus | 0.0038 | 0.2247 | 0.5 | |
Leishmania major | prostaglandin f synthase, putative | 0.0038 | 0.2247 | 0.5 |
Onchocerca volvulus | 0.0038 | 0.2247 | 0.5 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Echinococcus multilocularis | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Echinococcus multilocularis | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Onchocerca volvulus | 0.0038 | 0.2247 | 0.5 | |
Trypanosoma cruzi | aldo-keto reductase | 0.0038 | 0.2247 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0038 | 0.2247 | 0.2247 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0038 | 0.2247 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0038 | 0.2247 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0038 | 0.2247 | 0.2247 |
Echinococcus multilocularis | aldo keto reductase | 0.0038 | 0.2247 | 0.2247 |
Onchocerca volvulus | 0.0038 | 0.2247 | 0.5 | |
Mycobacterium ulcerans | oxidoreductase | 0.0038 | 0.2247 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0038 | 0.2247 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.