Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | ataxin-2 like protein, putative | 0.0018 | 0.8593 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0019 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.9606 | 0.9606 |
Schistosoma mansoni | intermediate filament proteins | 0.0019 | 1 | 0.5 |
Schistosoma mansoni | lamin | 0.0019 | 1 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0018 | 0.8593 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0018 | 0.8593 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0018 | 0.8593 | 0.5 |
Brugia malayi | hypothetical protein | 0.0018 | 0.8593 | 0.8593 |
Brugia malayi | hypothetical protein | 0.0012 | 0.1458 | 0.1458 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0019 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.8593 | 0.5 |
Schistosoma mansoni | lamin | 0.0019 | 1 | 0.5 |
Echinococcus multilocularis | lamin | 0.0019 | 1 | 0.5 |
Echinococcus multilocularis | musashi | 0.0019 | 1 | 0.5 |
Onchocerca volvulus | 0.0019 | 1 | 0.5 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0018 | 0.8593 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0019 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.8593 | 0.8593 |
Echinococcus granulosus | lamin | 0.0019 | 1 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0019 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0019 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0018 | 0.8593 | 0.5 |
Onchocerca volvulus | 0.0019 | 1 | 0.5 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0019 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0018 | 0.8593 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
T/C (functional) | = 0 % | Compound was tested for in vivo growth inhibition of pancreatic ductal adenocarcinoma (Panc 03) in mice, expressed as antitumour efficacy | ChEMBL. | 8145227 |
T/C (functional) | = 0 % | Compound was tested for in vivo growth inhibition of pancreatic ductal adenocarcinoma (Panc 03) in mice, expressed as antitumour efficacy | ChEMBL. | 8145227 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.