Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | adenosine deaminase, putative | 0.0517 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0517 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0517 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0517 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0517 | 1 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0517 | 1 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0517 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0517 | 1 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0517 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0517 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0517 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0517 | 1 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0517 | 1 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0517 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0517 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0517 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0517 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0517 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | 0 uM | Antiviral activity of compound against HIV-1 infected CEM-SS cells was determined in XTT cytoprotection assay; not tested | ChEMBL. | 9888834 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.