Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Mean survival time (functional) | = 5.7 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice. Increase in mean survival time in days was reported, at 80 mg/kg dosage of the compound. | ChEMBL. | 6361257 |
Mean survival time (functional) | = 5.7 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice. Increase in mean survival time in days was reported, at 80 mg/kg dosage of the compound. | ChEMBL. | 6361257 |
Mean survival time (functional) | = 5.9 day | Increase in mean survival time in mice innoculated with P. berghei days was reported following 40 mg/kg. | ChEMBL. | 6361257 |
Mean survival time (functional) | = 5.9 day | Increase in mean survival time in mice innoculated with P. berghei days was reported following 40 mg/kg. | ChEMBL. | 6361257 |
No. of cures (functional) | = 1 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice. at 320 mg/kg dosage of the compound; Toxic | ChEMBL. | 6361257 |
No. of cures (functional) | = 1 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 640 mg/kg dosage of the compound; Toxic | ChEMBL. | 6361257 |
No. of cures (functional) | = 1 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice. at 320 mg/kg dosage of the compound; Toxic | ChEMBL. | 6361257 |
No. of cures (functional) | = 1 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 640 mg/kg dosage of the compound; Toxic | ChEMBL. | 6361257 |
No. of cures (functional) | = 2 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 160 mg/kg dosage of the compound; Cure | ChEMBL. | 6361257 |
No. of cures (functional) | = 2 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 640 mg/kg dosage of the compound; Cure | ChEMBL. | 6361257 |
No. of cures (functional) | = 2 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 160 mg/kg dosage of the compound; Cure | ChEMBL. | 6361257 |
No. of cures (functional) | = 2 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 640 mg/kg dosage of the compound; Cure | ChEMBL. | 6361257 |
No. of cures (functional) | = 3 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 320 mg/kg dosage of the compound; Cure | ChEMBL. | 6361257 |
No. of cures (functional) | = 3 day | Antimalarial activity of the compound was assessed against Plasmodium berghei in mice at 320 mg/kg dosage of the compound; Cure | ChEMBL. | 6361257 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.