Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.125 ug ml-1 | Minimum inhibitory concentration against Enterobacter cloacae P99 (Class Ia beta-lactamase overproducer) | ChEMBL. | 2153215 |
MIC (functional) | = 0.25 ug ml-1 | In vitro antibacterial activity was determined against Escherichia coli ATCC 25922 | ChEMBL. | 2153215 |
MIC (functional) | = 0.25 ug ml-1 | In vitro antibacterial activity was determined against Escherichia coli ATCC 25922 | ChEMBL. | 2153215 |
MIC (functional) | = 0.5 ug ml-1 | Minimum inhibitory concentration against Escherichia coli TEM-1 (TEM-1 (class IIIa) beta-lactamase producer) | ChEMBL. | 2153215 |
MIC (functional) | = 0.5 ug ml-1 | Evaluated for the minimum inhibitory concentration against Serratia marcescens 1071 | ChEMBL. | 2153215 |
MIC (functional) | = 0.5 ug ml-1 | Evaluated for the minimum inhibitory concentration against Proteus vulgaris 1028 BC (Class Ic beta-lactamase overproducer | ChEMBL. | 2153215 |
MIC (functional) | = 0.5 ug ml-1 | Evaluated for the minimum inhibitory concentration against Pseudomonas aeruginosa 18S/H (Class Id beta-lactamase overproducer) | ChEMBL. | 2153215 |
MIC (functional) | = 0.5 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus ATCC 29213 (inducible, low level beta-lactamase producer) | ChEMBL. | 2153215 |
MIC (functional) | = 0.5 ug ml-1 | Minimum inhibitory concentration against Escherichia coli TEM-1 (TEM-1 (class IIIa) beta-lactamase producer) | ChEMBL. | 2153215 |
MIC (functional) | = 1 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus 1059B (inducible, high level beta-lactamase producer) | ChEMBL. | 2153215 |
MIC (functional) | = 1 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus 95 (Methicillin-resistant, high-level beta-lactamase producer) | ChEMBL. | 2153215 |
MIC (functional) | = 32 ug ml-1 | Evaluated for the minimum inhibitory concentration against Citrobacter freundii BS-16. | ChEMBL. | 2153215 |
MIC (functional) | = 32 ug ml-1 | Minimum inhibitory concentration against Proteus mirabilis 90 | ChEMBL. | 2153215 |
MIC (functional) | = 64 ug ml-1 | Minimum inhibitory concentration against Streptococcus pneumoniae 6301 | ChEMBL. | 2153215 |
MIC (functional) | = 64 ug ml-1 | Evaluated for the minimum inhibitory concentration against Enterococcus faecalis ATCC 29212 | ChEMBL. | 2153215 |
MIC (functional) | > 128 ug ml-1 | Minimum inhibitory concentration against Streptococcus pyogenes 4 | ChEMBL. | 2153215 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.