Detailed information for compound 290353

Basic information

Technical information
  • TDR Targets ID: 290353
  • Name: N-[4-(methoxymethyl)-1-[2-(2-oxo-3H-indol-1-y l)ethyl]piperidin-4-yl]-N-phenylpropanamide
  • MW: 435.559 | Formula: C26H33N3O3
  • H donors: 0 H acceptors: 2 LogP: 2.74 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCC1(CCN(CC1)CCN1C(=O)Cc2c1cccc2)N(c1ccccc1)C(=O)CC
  • InChi: 1S/C26H33N3O3/c1-3-24(30)29(22-10-5-4-6-11-22)26(20-32-2)13-15-27(16-14-26)17-18-28-23-12-8-7-9-21(23)19-25(28)31/h4-12H,3,13-20H2,1-2H3
  • InChiKey: KMZHNHUUGMCSMN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-(methoxymethyl)-1-[2-(2-oxoindolin-1-yl)ethyl]-4-piperidyl]-N-phenyl-propanamide
  • N-[4-(methoxymethyl)-1-[2-(2-oxo-1-indolinyl)ethyl]-4-piperidinyl]-N-phenylpropanamide
  • N-[4-(methoxymethyl)-1-[2-(2-oxo-3H-indol-1-yl)ethyl]piperidin-4-yl]-N-phenyl-propanamide
  • N-[1-[2-(2-ketoindolin-1-yl)ethyl]-4-(methoxymethyl)-4-piperidyl]-N-phenyl-propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0069 0.0332 0.1023
Brugia malayi hypothetical protein 0.002 0.0088 0.0079
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0006 0.0015 0.0047
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0008 0.0025 0.0016
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0008 0.0027 0.007
Echinococcus multilocularis ATP binding cassette sub family B 0.0004 0.0009 0.0009
Echinococcus multilocularis lachesin 0.0005 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0078 0.0073
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1316
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0069 0.0332 0.0668
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0076 0.0149
Plasmodium vivax ferrodoxin reductase, putative 0.0008 0.0025 0.0048
Echinococcus granulosus caspase 0.0018 0.0078 0.0152
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0007 0.0022 0.0037
Echinococcus multilocularis para nitrobenzyl esterase 0.0114 0.0553 0.1136
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0008 0.0025 0.0048
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0008 0.0025 0.0048
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0006 0.0015 0.0047
Brugia malayi amine oxidase, flavin-containing family protein 0.0082 0.0394 0.0385
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Brugia malayi SWIRM domain containing protein 0.0082 0.0394 0.0385
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0633 0.3138 0.967
Brugia malayi Immunoglobulin domain containing protein 0.0005 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Onchocerca volvulus 0.0069 0.0332 0.0323
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Entamoeba histolytica multidrug resistance protein, putative 0.0006 0.0015 0.0018
Loa Loa (eye worm) oxidoreductase 0.0005 0.001 0.0005
Echinococcus multilocularis multidrug resistance associated protein 7 0.0006 0.0015 0.0022
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0069 0.0332 0.0668
Onchocerca volvulus 0.0016 0.0065 0.0055
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0005 0.001 0.0006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0008 0.0025 0.0063
Giardia lamblia ABC transporter, putative 0.0006 0.0015 0.0001
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0082 0.0394 0.9039
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114 0.0553 0.1127
Onchocerca volvulus Cell death protein 3 homolog 0.0018 0.0078 0.0069
Brugia malayi hypothetical protein 0.0042 0.0197 0.0188
Onchocerca volvulus 0.0114 0.0553 0.0544
Schistosoma mansoni CD36-like class B scavenger receptor 0.0112 0.0543 0.1105
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0005 0.0009 0.001
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0005 0.0013 0.0007
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0005 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0082 0.0394 0.9038
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0008 0.0025 0.0026
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0069 0.0332 0.0668
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0076 0.0149
Brugia malayi ABC transporter transmembrane region family protein 0.0006 0.0015 0.0006
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0005 0.001 0.0006
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0012 0.0045 0.0836
Brugia malayi glutamate synthase 0.0008 0.0025 0.0016
Leishmania major acetyl-CoA synthetase, putative 0.0005 0.001 0.003
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0075 0.0358 0.0731
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0567 0.2806 0.5798
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0005 0.0009 0.001
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0008 0.0025 0.0042
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0114 0.0553 0.1136
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0005 0.001 0.0016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.013 0.0251
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0027 0.0123 0.035
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0655 0.3245 0.3241
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.009 0.0435 1
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0065 0.0055
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.009 0.0435 0.1315
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1163 0.5772 1
Plasmodium vivax glutathione reductase, putative 0.0083 0.0401 0.1211
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus granulosus multidrug resistance associated protein 1 0.0006 0.0015 0.0022
Trypanosoma brucei metacaspase MCA2 0.0018 0.0078 0.0212
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Loa Loa (eye worm) protein tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus multilocularis mitogen activated protein kinase 11 0.0633 0.3138 0.6485
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0008 0.0025 0.0359
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0025 0.0063
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0008 0.0025 0.0042
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0015 0.0062 0.012
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0069 0.0332 0.0323
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0008 0.0025 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0078 0.0213
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0018 0.0078 0.0152
Echinococcus multilocularis roundabout 2 0.0005 0.0013 0.0017
Trypanosoma brucei metacaspase 0.0018 0.0078 0.0212
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0092 0.0083
Schistosoma mansoni hypothetical protein 0.0018 0.0076 0.0139
Onchocerca volvulus 0.0015 0.0062 0.0053
Echinococcus multilocularis CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Echinococcus multilocularis mitogen activated protein kinase 14 0.0633 0.3138 0.6485
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0008 0.0025 0.0034
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0092 0.0083
Trypanosoma cruzi metacaspase, putative 0.0018 0.0078 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Toxoplasma gondii thioredoxin reductase 0.0083 0.0401 0.9203
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Onchocerca volvulus 0.0069 0.0332 0.0323
Trichomonas vaginalis fk506-binding protein, putative 0.009 0.0435 0.1316
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0655 0.3245 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Giardia lamblia Multidrug resistance-associated protein 1 0.0006 0.0015 0.0001
Plasmodium falciparum metacaspase-like protein 0.0018 0.0078 0.0213
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Echinococcus granulosus BC026374 protein S09 family 0.0114 0.0553 0.1136
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.009 0.0435 0.1301
Schistosoma mansoni septate junction protein 0.0005 0.0013 0.0007
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0008 0.0025 0.0026
Entamoeba histolytica HEAT repeat domain containing protein 0.0007 0.0022 0.0038
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.009 0.0435 0.1301
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0016 0.0065 0.0095
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0655 0.3245 0.6703
Plasmodium vivax transportin, putative 0.0007 0.0022 0.0038
Leishmania major ABC-thiol transporter 0.0006 0.0015 0.0047
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0076 0.0071
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0069 0.0332 0.0994
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0075 0.0358 0.0731
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.009 0.0435 0.1329
Echinococcus multilocularis tyrosine protein kinase otk 0.0005 0.0013 0.0017
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.013 0.0374
Onchocerca volvulus 0.0069 0.0332 0.0323
Echinococcus multilocularis netrin receptor unc 5 0.0005 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0082 0.0394 0.0389
Echinococcus granulosus tyrosine protein kinase otk 0.0005 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0005 0.001 0.0006
Echinococcus multilocularis Immunoglobulin 0.0005 0.0013 0.0017
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0005 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Loa Loa (eye worm) isocitrate dehydrogenase 0.0008 0.0027 0.0022
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0078 0.1615
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0005 0.0013 0.0007
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0114 0.0553 0.1136
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0069 0.0332 0.0677
Echinococcus multilocularis isocitrate dehydrogenase 0.0008 0.0027 0.0047
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0112 0.0543 0.1105
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0065 0.0095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0388
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0027 0.0123 0.0113
Leishmania major hypothetical protein, conserved 0.0007 0.0022 0.0067
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0005 0.0013 0.0017
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0111 0.0221
Schistosoma mansoni basigin related 0.0005 0.0013 0.0007
Onchocerca volvulus 0.0069 0.0332 0.0323
Schistosoma mansoni immunophilin 0.0567 0.2806 0.5794
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0005 0.0009 0.001
Echinococcus granulosus multidrug resistance protein 1 0.0005 0.0009 0.001
Onchocerca volvulus 0.0069 0.0332 0.0323
Mycobacterium tuberculosis Probable reductase 0.0008 0.0025 0.0034
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0005 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0015 0.0018
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0005 0.0009 0.0004
Trypanosoma brucei protein tyrosine phosphatase 1 0.0069 0.0332 0.0996
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0006 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0633 0.3138 0.967
Loa Loa (eye worm) hypothetical protein 0.0012 0.0045 0.004
Schistosoma mansoni nephrin related 0.0005 0.0013 0.0007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus multilocularis fk506 binding protein 0.0655 0.3245 0.6707
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0082 0.0394 0.1189
Schistosoma mansoni importin-beta 2 0.0007 0.0022 0.0025
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0005 0.0013 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0687 0.1405
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Schistosoma mansoni acetylcholinesterase 0.0114 0.0553 0.1127
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0005 0.001 0.0006
Trypanosoma cruzi UDP-galactopyranose mutase 0.0082 0.0394 0.1202
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0394 0.1189
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0008 0.0025 0.0031
Onchocerca volvulus 0.0069 0.0332 0.0323
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.009 0.0435 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0069 0.0332 0.0668
Echinococcus granulosus lysosome membrane protein 2 0.0112 0.0543 0.1114
Echinococcus granulosus basement membrane specific heparan sulfate 0.0005 0.0013 0.0017
Mycobacterium ulcerans ferredoxin reductase 0.0008 0.0025 0.0026
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0069 0.0332 0.0677
Echinococcus multilocularis CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0112 0.0543 0.0534
Onchocerca volvulus 0.0025 0.0111 0.0102
Mycobacterium tuberculosis Carboxylesterase LipT 0.0999 0.4958 0.9241
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114 0.0553 0.1127
Onchocerca volvulus Tyrosine kinase homolog 0.0015 0.0062 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.013 0.0373
Schistosoma mansoni pcd6 interacting protein-related 0.0069 0.0332 0.0668
Loa Loa (eye worm) programmed cell death 8 0.0008 0.0025 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0027 0.0123 0.0364
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0082 0.0394 0.0667
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0069 0.0332 0.101
Echinococcus multilocularis CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Schistosoma mansoni multidrug resistance protein 0.0006 0.0015 0.0012
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0008 0.0025 0.0042
Leishmania major trypanothione reductase 0.0083 0.0401 0.1236
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.013 0.0374
Leishmania major peptidylprolyl isomerase-like protein 0.0655 0.3245 1
Brugia malayi hypothetical protein 0.0082 0.0394 0.0385
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0042 0.0066
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.013 0.0231
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0008 0.0025 0.0034
Trichomonas vaginalis immunophilin, putative 0.0655 0.3245 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0008 0.0025 0.0048
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0006 0.0015 0.001
Echinococcus granulosus acetylcholinesterase 0.0114 0.0553 0.1136
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0076 0.0149
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0078 0.1615
Plasmodium vivax importin-beta 2, putative 0.0037 0.0171 0.0501
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0388
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0042 0.0066
Onchocerca volvulus 4.1 G protein, putative homolog 0.0069 0.0332 0.0323
Brugia malayi CD36 family protein 0.0112 0.0543 0.0534
Loa Loa (eye worm) hypothetical protein 0.0004 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0974 0.4836 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0006 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0567 0.2806 0.5798
Loa Loa (eye worm) thioredoxin reductase 0.0083 0.0401 0.0396
Schistosoma mansoni hypothetical protein 0.0018 0.0076 0.0139
Toxoplasma gondii HEAT repeat-containing protein 0.0007 0.0022 0.0289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.013 0.0373
Schistosoma mansoni hypothetical protein 0.0005 0.0013 0.0007
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0008 0.0025 0.0048
Echinococcus multilocularis neuroglian 0.0005 0.0013 0.0017
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0015 0.0018
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0082 0.0394 0.0797
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0008 0.0025 0.0048
Brugia malayi hypothetical protein 0.0069 0.0332 0.0323
Echinococcus granulosus CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.013 0.0374
Echinococcus multilocularis 0.009 0.0435 0.0891
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.009 0.0435 0.1312
Trypanosoma brucei metacaspase MCA3 0.0018 0.0078 0.0212
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0008 0.0025 0.0047
Schistosoma mansoni netrin receptor unc5 0.0005 0.0013 0.0007
Echinococcus multilocularis 0.0069 0.0332 0.0677
Trypanosoma brucei p-glycoprotein 0.0006 0.0015 0.0018
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0006 0.0015 0.0018
Schistosoma mansoni peroxidasin 0.0005 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0008 0.0025 0.0048
Brugia malayi glutathione reductase 0.0083 0.0401 0.0392
Leishmania major p-glycoprotein 0.0005 0.0009 0.0029
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0008 0.0025 0.0026
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0069 0.0332 0.0323
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0078 0.0227
Onchocerca volvulus 0.0114 0.0553 0.0544
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0008 0.0025 0.0063
Treponema pallidum NADH oxidase 0.0029 0.013 0.0328
Echinococcus multilocularis multidrug resistance protein 1 0.0005 0.0009 0.001
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.002 0.0088 0.0164
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0008 0.0027 0.0055
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0655 0.3245 1
Trichomonas vaginalis fk506-binding protein, putative 0.009 0.0435 0.1316
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0008 0.0025 0.0034
Echinococcus granulosus peroxidasin 0.0005 0.0013 0.0017
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0016 0.0065 0.1293
Brugia malayi Importin beta-1 subunit 0.0037 0.0171 0.0162
Onchocerca volvulus 0.0069 0.0332 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0078 0.0213
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.013 0.0402
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0082 0.0394 0.0389
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0008 0.0025 0.0048
Trypanosoma cruzi metacaspase, putative 0.0018 0.0078 0.0227
Mycobacterium ulcerans glutamate synthase subunit beta 0.0008 0.0025 0.0026
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0016 0.0065 0.1293
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0657 0.3254 0.6726
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0008 0.0027 0.0055
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Onchocerca volvulus 0.0114 0.0553 0.0544
Trypanosoma cruzi importin beta-1 subunit, putative 0.003 0.0136 0.0407
Echinococcus granulosus para nitrobenzyl esterase 0.0114 0.0553 0.1136
Leishmania major pentamidine resistance protein 1 0.0006 0.0015 0.0047
Echinococcus granulosus importin subunit beta 1 0.0037 0.0171 0.0345
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.013 0.2842
Schistosoma mansoni multidrug resistance protein 0.0006 0.0015 0.0012
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0008 0.0025 0.0048
Schistosoma mansoni hypothetical protein 0.0005 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0069 0.0332 0.0668
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.013 0.021
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0005 0.0009 0.001
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.009 0.0435 0.0891
Loa Loa (eye worm) hypothetical protein 0.0037 0.0171 0.0167
Loa Loa (eye worm) hypothetical protein 0.0025 0.0111 0.0106
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0008 0.0025 0.0077
Entamoeba histolytica ABC transporter, putative 0.0006 0.0015 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0029 0.013 0.0231
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0008 0.0025 0.0034
Entamoeba histolytica disulphide oxidoreductase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Echinococcus multilocularis snurportin 1 0.0396 0.1958 0.4043
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0005 0.0013 0.0017
Mycobacterium ulcerans oxidoreductase 0.0082 0.0394 0.0667
Schistosoma mansoni hypothetical protein 0.0039 0.018 0.0355
Echinococcus multilocularis translational activator gcn1 0.0007 0.0022 0.0035
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0032
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Schistosoma mansoni ran 0.0027 0.0123 0.0235
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.009 0.0435 1
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0008 0.0025 0.0026
Plasmodium falciparum importin beta, putative 0.0037 0.0171 0.0501
Brugia malayi Protein-tyrosine phosphatase 1 0.0069 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0012 0.0045 0.004
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Schistosoma mansoni hypothetical protein 0.0018 0.0076 0.0139
Echinococcus multilocularis neuroligin 0.0114 0.0553 0.1136
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0655 0.3245 0.3238
Brugia malayi Protein-tyrosine phosphatase 0.0069 0.0332 0.0323
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0008 0.0025 0.0048
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0005 0.0013 0.0007
Giardia lamblia Protein tyrosine phosphatase 0.0069 0.0332 0.0981
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0394 0.1189
Trichomonas vaginalis spcc417.12 protein, putative 0.0114 0.0553 0.1681
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0655 0.3245 0.6707
Echinococcus multilocularis carboxylesterase 5A 0.0114 0.0553 0.1136
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0655 0.3245 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0069 0.0332 0.0677
Loa Loa (eye worm) TAR-binding protein 0.0141 0.0687 0.0683
Loa Loa (eye worm) hypothetical protein 0.0042 0.0197 0.0192
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0005 0.001 0.001
Leishmania major importin beta-1 subunit, putative 0.003 0.0136 0.0421
Schistosoma mansoni tyrosine kinase 0.0005 0.0013 0.0007
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0008 0.0027 0.0084
Onchocerca volvulus 0.0114 0.0553 0.0544
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0008 0.0025 0.0359
Onchocerca volvulus 0.0199 0.0976 0.0967
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.009 0.0435 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0005 0.001 0.0006
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1312
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.009 0.0435 1
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1341
Schistosoma mansoni protein tyrosine phosphatase 0.0069 0.0332 0.0668
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0005 0.001 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Echinococcus multilocularis roundabout 2 0.0005 0.0013 0.0017
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0069 0.0332 0.0668
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0078 0.0213
Loa Loa (eye worm) hypothetical protein 0.009 0.0435 0.043
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0008 0.0025 0.0042
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0005 0.0009 0.001
Echinococcus granulosus CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Plasmodium falciparum protoporphyrinogen oxidase 0.0082 0.0394 0.1189
Echinococcus granulosus transportin 1 0.0007 0.0022 0.0035
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Toxoplasma gondii selenide, water dikinase 0.0008 0.0025 0.0364
Onchocerca volvulus 0.0069 0.0332 0.0323
Trichomonas vaginalis apoptosis inducing factor, putative 0.0008 0.0025 0.0048
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0005 0.001 0.0006
Plasmodium vivax acetyl-CoA synthetase, putative 0.0005 0.001 0.0001
Mycobacterium tuberculosis Possible oxidoreductase 0.0082 0.0394 0.0724
Leishmania major 4-coumarate:coa ligase-like protein 0.0016 0.0065 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0078 0.0213
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0655 0.3245 1
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0435 0.1316
Echinococcus multilocularis Immunoglobulin subtype 0.0005 0.0013 0.0017
Schistosoma mansoni disulfide oxidoreductase 0.0008 0.0025 0.0032
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0005 0.001 0.0006
Onchocerca volvulus 0.0082 0.0394 0.0385
Echinococcus multilocularis CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Brugia malayi Peroxidasin 0.0005 0.0013 0.0003
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0008 0.0025 0.0026
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0069 0.0332 0.0668
Giardia lamblia Glutamate synthase 0.0008 0.0025 0.0031
Brugia malayi Carboxylesterase family protein 0.0114 0.0553 0.0544
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.027 0.0261
Schistosoma mansoni roundabout 0.0005 0.0013 0.0007
Echinococcus multilocularis importin subunit beta 1 0.0037 0.0171 0.0345
Echinococcus multilocularis GPCR, family 2 0.0018 0.0076 0.0149
Trypanosoma brucei multidrug resistance protein E 0.0006 0.0015 0.0018
Mycobacterium ulcerans dehydrogenase 0.0082 0.0394 0.0667
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0009 0.0033 0.0073
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1341
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0402
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0008 0.0025 0.0048
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.009 0.0435 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.013 0.0373
Trypanosoma brucei importin beta-1 subunit, putative 0.0037 0.0171 0.05
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0008 0.0025 0.0359
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.009 0.0435 1
Onchocerca volvulus 0.0015 0.0062 0.0053
Toxoplasma gondii isocitrate dehydrogenase 0.0008 0.0027 0.0421
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0029 0.013 0.2842
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Echinococcus granulosus CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Echinococcus granulosus acetylcholinesterase 0.0114 0.0553 0.1136
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.013 0.021
Plasmodium falciparum ferrodoxin reductase-like protein 0.0008 0.0025 0.0048
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Onchocerca volvulus 0.0069 0.0332 0.0323
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0005 0.0013 0.0007
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.013 0.2572
Entamoeba histolytica thioredoxin reductase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0082 0.0394 0.0389
Onchocerca volvulus 0.0069 0.0332 0.0323
Schistosoma mansoni multidrug resistance protein 0.0006 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0082 0.0394 0.0389
Echinococcus granulosus CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0655 0.3245 1
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0655 0.3245 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0008 0.0025 0.0063
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0065 0.0109
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0111 0.0211
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1163 0.5772 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Leishmania major GTP-binding protein, putative 0.0027 0.0123 0.0378
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0005 0.0013 0.0017
Loa Loa (eye worm) LAD-2 short isoform 0.0005 0.0013 0.0008
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0005 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.006
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0008 0.0027 0.0055
Trichomonas vaginalis antibiotic synthetase, putative 0.0005 0.001 0.0001
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0005 0.0013 0.0017
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0027 0.0123 0.0118
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0005 0.001 0.0016
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0655 0.3246 0.324
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0069 0.0332 0.0677
Schistosoma mansoni glutamate synthase 0.0008 0.0025 0.0032
Schistosoma mansoni septate junction protein 0.0005 0.0013 0.0007
Echinococcus granulosus mitogen activated protein kinase 14 0.0633 0.3138 0.6485
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0008 0.0027 0.0055
Trichomonas vaginalis Importin beta-1 subunit, putative 0.003 0.0136 0.0393
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0008 0.0025 0.0016
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus multilocularis Immunoglobulin 0.0005 0.0013 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0078 0.0213
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0069 0.0332 0.0327
Toxoplasma gondii isocitrate dehydrogenase 0.0008 0.0027 0.0421
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0633 0.3138 0.3134
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0008 0.0027 0.007
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0005 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.001
Trichomonas vaginalis pten, drome, putative 0.0069 0.0332 0.0997
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0018 0.0078 0.0152
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.009 0.0435 0.1329
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0027 0.0123 0.0244
Trichomonas vaginalis ran, putative 0.0027 0.0123 0.035
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0008 0.0025 0.0034
Echinococcus granulosus Immunoglobulin subtype 0.0005 0.0013 0.0017
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0069 0.0332 0.0327
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0069 0.0332 0.101
Onchocerca volvulus 0.0069 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0565 0.2798 0.2795
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0974 0.4836 0.4831
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Leishmania major NADH dehydrogenase, putative 0.0008 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.0082 0.0394 0.0389
Schistosoma mansoni glutamate synthase 0.0008 0.0025 0.0032
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0008 0.0025 0.0063
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.013 0.026
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Schistosoma mansoni cell adhesion molecule 0.0005 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0029 0.013 0.0231
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0402
Echinococcus multilocularis mitogen activated protein kinase 11 0.0633 0.3138 0.6485
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.013 0.0121
Trypanosoma cruzi metacaspase, putative 0.0018 0.0078 0.0227
Echinococcus granulosus lachesin 0.0005 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0111 0.0221
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0388
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.001
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0655 0.3245 1
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.009 0.0435 0.1329
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0069 0.0332 0.0677
Brugia malayi basement membrane proteoglycan precursor 0.0005 0.0013 0.0003
Schistosoma mansoni cell adhesion molecule 0.0005 0.0013 0.0007
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0078 0.0142
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0027 0.0123 0.2661
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.0107 0.0212
Echinococcus granulosus importin 5 0.0007 0.0022 0.0035
Schistosoma mansoni amine oxidase 0.0082 0.0394 0.0797
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0112 0.0543 0.0538
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0005 0.001 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0016 0.0065 0.0109
Loa Loa (eye worm) hypothetical protein 0.0012 0.0045 0.004
Echinococcus multilocularis multidrug resistance protein 1 0.0005 0.0009 0.001
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0008 0.0025 0.0034
Echinococcus multilocularis glutamate synthase 0.0008 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0076 0.0071
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.009 0.0435 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0008 0.0027 0.0047
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0069 0.0332 0.0668
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0008 0.0025 0.0026
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0008 0.0024 0.0019
Echinococcus multilocularis caspase 0.0018 0.0078 0.0152
Plasmodium falciparum thioredoxin reductase 0.0029 0.013 0.0374
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0388
Trichomonas vaginalis fk506-binding protein, putative 0.0655 0.3245 1
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1316
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0005 0.0009 0.0029
Echinococcus granulosus caspase 2 0.0018 0.0078 0.0152
Leishmania major UDP-galactopyranose mutase 0.0082 0.0394 0.1215
Brugia malayi basement membrane proteoglycan 0.0005 0.0013 0.0003
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0069 0.0332 0.0668
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0655 0.3245 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.013 0.0374
Echinococcus multilocularis multidrug resistance associated protein 1 0.0006 0.0015 0.0022
Loa Loa (eye worm) carboxylesterase 0.0114 0.0553 0.0549
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0008 0.0025 0.0063
Trypanosoma cruzi metacaspase, putative 0.0018 0.0078 0.0227
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Echinococcus granulosus multidrug resistance protein 1 0.0005 0.0009 0.001
Leishmania major hypothetical protein, conserved 0.0008 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.013 0.0231
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0005 0.0013 0.0008
Schistosoma mansoni septate junction protein 0.0005 0.0013 0.0007
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0005 0.0009 0.001
Brugia malayi Carboxylesterase family protein 0.0114 0.0553 0.0544
Brugia malayi RNA binding protein 0.0141 0.0687 0.0679
Entamoeba histolytica Ran family GTPase 0.0027 0.0123 0.0349
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0027 0.0123 0.0349
Trichomonas vaginalis importin beta-1, putative 0.003 0.0136 0.0393
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0008 0.0025 0.0048
Toxoplasma gondii histone lysine-specific demethylase 0.0082 0.0394 0.9039
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Schistosoma mansoni hypothetical protein 0.0005 0.0013 0.0007
Echinococcus granulosus contactin 0.002 0.0088 0.0174
Schistosoma mansoni hypothetical protein 0.0396 0.1958 0.4037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0042 0.0066
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0006 0.0015 0.0047
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0078 0.0142
Brugia malayi Prion-like- 0.0005 0.0013 0.0003
Plasmodium falciparum thioredoxin reductase 0.0083 0.0401 0.1211
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0027 0.0123 0.035
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0008 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0112 0.0543 0.0538
Loa Loa (eye worm) carboxylesterase 0.0114 0.0553 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0435 0.1316
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0008 0.0025 0.0364
Schistosoma mansoni basigin related 0.0005 0.0013 0.0007
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0005 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0112 0.0543 0.0538
Schistosoma mansoni hypothetical protein 0.0015 0.0062 0.011
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.0176
Echinococcus granulosus neuroglian 0.0005 0.0013 0.0017
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.009 0.0435 0.08
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0974 0.4836 0.4833
Schistosoma mansoni titin 0.002 0.0088 0.0164
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0657 0.3254 1
Giardia lamblia MRP-like ABC transporter 0.0006 0.0015 0.0001
Loa Loa (eye worm) hypothetical protein 0.0057 0.027 0.0265
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0005 0.001 0.0005
Onchocerca volvulus 0.0069 0.0332 0.0323
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Echinococcus granulosus carboxylesterase 5A 0.0114 0.0553 0.1136
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0012 0.0045 0.0061
Echinococcus granulosus translational activator gcn1 0.0007 0.0022 0.0035
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.013 0.026
Brugia malayi Pre-SET motif family protein 0.0175 0.0856 0.0847
Leishmania major 4-coumarate:coa ligase-like protein 0.0016 0.0065 0.0199
Echinococcus granulosus lysine specific histone demethylase 1A 0.0082 0.0394 0.0806
Schistosoma mansoni hypothetical protein 0.0005 0.0013 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0092 0.0444 0.091
Loa Loa (eye worm) FKBP5 protein 0.0655 0.3245 0.3241
Plasmodium vivax metacaspase 1, putative 0.0018 0.0078 0.0213
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1329
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0004
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0008 0.0025 0.0364
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0657 0.3254 0.6726
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0016 0.0065 0.0095
Schistosoma mansoni hypothetical protein 0.0005 0.0013 0.0007
Schistosoma mansoni sulfide quinone reductase 0.0008 0.0025 0.0032
Schistosoma mansoni protein tyrosine phosphatase 0.0069 0.0332 0.0668
Schistosoma mansoni glutamate synthase 0.0008 0.0025 0.0032
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0005 0.001 0.001
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0008 0.0025 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0065 0.0095
Brugia malayi multidrug resistance related protein 1 0.0006 0.0015 0.0006
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0062 0.0053
Brugia malayi Carboxylesterase family protein 0.0114 0.0553 0.0544
Loa Loa (eye worm) hypothetical protein 0.0082 0.0394 0.0389
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0069 0.0332 0.0677
Giardia lamblia Multidrug resistance-associated protein 1 0.0006 0.0015 0.0001
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0005 0.0013 0.0017
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0008 0.0025 0.0034
Toxoplasma gondii HEAT repeat-containing protein 0.0007 0.0022 0.0289
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0082 0.0394 0.1189
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0111 0.2396
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0076 0.0067
Trypanosoma cruzi NADH dehydrogenase, putative 0.0008 0.0025 0.0063
Mycobacterium ulcerans monoamine oxidase 0.0082 0.0394 0.0667
Leishmania major metacaspase, putative 0.0018 0.0078 0.0241
Schistosoma mansoni cell adhesion molecule 0.0005 0.0013 0.0007
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0075 0.0358 0.0722
Leishmania major hypothetical protein, conserved 0.0008 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Brugia malayi Immunoglobulin domain containing protein 0.0005 0.0013 0.0003
Schistosoma mansoni sulfide quinone reductase 0.0008 0.0025 0.0032
Brugia malayi Carboxylesterase family protein 0.0114 0.0553 0.0544
Onchocerca volvulus 0.0069 0.0332 0.0323
Brugia malayi hypothetical protein 0.0069 0.0332 0.0323
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0008 0.0027 0.0039
Echinococcus granulosus neuroligin 0.0114 0.0553 0.1136
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0078 0.1615
Trypanosoma cruzi trypanothione reductase, putative 0.0083 0.0401 0.1224
Echinococcus multilocularis caspase 2 0.0018 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Echinococcus granulosus thioredoxin glutathione reductase 0.0083 0.0401 0.0821
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0005 0.001 0.0016
Schistosoma mansoni cell adhesion molecule 0.0005 0.0013 0.0007
Echinococcus granulosus GPCR family 2 0.0018 0.0076 0.0149
Echinococcus multilocularis hemicentin 1 0.0005 0.0013 0.0017
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0005 0.0013 0.0008
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.009 0.0435 0.0426
Echinococcus multilocularis mitogen activated protein kinase 14 0.0633 0.3138 0.6485
Onchocerca volvulus Putative titin 0.0015 0.0062 0.0053
Loa Loa (eye worm) hypothetical protein 0.0042 0.0197 0.0192
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0687 0.1405
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0027 0.0123 0.0364
Echinococcus granulosus GTP binding nuclear protein Ran 0.0027 0.0123 0.0244
Echinococcus multilocularis acetylcholinesterase 0.0114 0.0553 0.1136
Echinococcus granulosus multidrug resistance protein 1 0.0005 0.0009 0.001
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0008 0.0025 0.0026
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0008 0.0025 0.0048
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Loa Loa (eye worm) hypothetical protein 0.0005 0.001 0.0005
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0974 0.4836 1
Onchocerca volvulus Basement membrane proteoglycan homolog 0.002 0.0088 0.0079
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Trichomonas vaginalis set domain proteins, putative 0.0199 0.0976 0.2987
Brugia malayi Cell death protein 3 precursor 0.0018 0.0078 0.0069
Echinococcus granulosus roundabout 2 0.0005 0.0013 0.0017
Echinococcus multilocularis transportin 1 0.0007 0.0022 0.0035
Trichomonas vaginalis glutamate synthase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Mycobacterium ulcerans monoxygenase 0.0008 0.0025 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Brugia malayi hypothetical protein 0.0042 0.0197 0.0188
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0042 0.0066
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0008 0.0025 0.0016
Giardia lamblia Hypothetical protein 0.009 0.0435 0.1301
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0008 0.0025 0.0364
Echinococcus granulosus multidrug resistance associated protein 7 0.0006 0.0015 0.0022
Onchocerca volvulus 0.0015 0.0062 0.0053
Schistosoma mansoni importin beta-1 0.0037 0.0171 0.0336
Mycobacterium ulcerans hypothetical protein 0.009 0.0435 0.0738
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0008 0.0025 0.0034
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0069 0.0332 0.0677
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0111 0.0211
Trypanosoma cruzi NADH dehydrogenase, putative 0.0008 0.0025 0.0063
Trypanosoma cruzi UDP-galactopyranose mutase 0.0082 0.0394 0.1202
Brugia malayi kap beta 3 protein 0.0007 0.0022 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0027 0.0047
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0069 0.0332 0.0677
Loa Loa (eye worm) kap beta 3 protein 0.0007 0.0022 0.0017
Onchocerca volvulus 0.0008 0.0025 0.0016
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0069 0.0332 0.0668
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Trypanosoma brucei metacaspase 5, putative 0.0018 0.0078 0.0212
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0008 0.0025 0.0048
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0027 0.0123 0.0333
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0076 0.0067
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0008 0.0027 0.0037
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0005 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.001
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0069 0.0332 0.0677
Schistosoma mansoni multidrug resistance protein 0.0006 0.0015 0.0012
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0008 0.0025 0.0359
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus granulosus roundabout 2 0.0005 0.0013 0.0017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0175 0.0856 0.0851
Onchocerca volvulus 0.0069 0.0332 0.0323
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Brugia malayi Pre-SET motif family protein 0.0025 0.0111 0.0102
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0005 0.001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0008 0.0025 0.0047
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0655 0.3245 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0008 0.0025 0.0034
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0027 0.0047
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.009 0.0435 0.043
Mycobacterium ulcerans dehydrogenase 0.0008 0.0025 0.0026
Onchocerca volvulus 0.2012 1 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.013 0.0388
Toxoplasma gondii propionate-CoA ligase 0.0005 0.001 0.0006
Brugia malayi hypothetical protein 0.0114 0.0553 0.0544
Onchocerca volvulus 0.009 0.0435 0.0426
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0111 0.0221
Plasmodium vivax SET domain protein, putative 0.0025 0.0111 0.0315
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0069 0.0332 0.0327
Entamoeba histolytica hypothetical protein 0.003 0.0136 0.0392
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0008 0.0025 0.0359
Onchocerca volvulus 0.0069 0.0332 0.0323
Onchocerca volvulus 0.0069 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0657 0.3254 1
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0006 0.0015 0.0047
Schistosoma mansoni nephrin 0.0005 0.0013 0.0007
Echinococcus granulosus tar DNA binding protein 0.0141 0.0687 0.1413
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Plasmodium falciparum acyl-CoA synthetase 0.0012 0.0045 0.011
Trichomonas vaginalis hypothetical protein 0.0007 0.0022 0.0038
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0006 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0324 0.1598 0.1594
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0633 0.3138 0.967
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0012 0.0045 0.0072
Schistosoma mansoni hypothetical protein 0.0018 0.0076 0.0139
Leishmania major acetyl-CoA synthetase, putative 0.0005 0.001 0.003
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0005 0.0013 0.0017
Schistosoma mansoni amine oxidase 0.0082 0.0394 0.0797
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0016 0.0065 0.0095
Mycobacterium tuberculosis Probable dehydrogenase 0.0008 0.0025 0.0034
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0069 0.0332 0.0994
Trypanosoma cruzi multidrug resistance protein E, putative 0.0006 0.0015 0.0033
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0008 0.0027 0.0047
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.027 0.0265
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.013 0.0402
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0655 0.3245 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0114 0.0553 0.1681
Trichomonas vaginalis glutamate synthase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.006
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0065 0.0095
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0069 0.0332 0.0677
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.009 0.0435 0.043
Loa Loa (eye worm) protein-tyrosine phosphatase 0.2012 1 1
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0069 0.0332 0.0677
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0082 0.0394 0.0797
Trypanosoma brucei Metacaspase-4 0.0018 0.0078 0.0212
Echinococcus granulosus lysine specific histone demethylase 1A 0.0082 0.0394 0.0806
Giardia lamblia Thioredoxin reductase 0.0008 0.0025 0.0031
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0069 0.0332 0.0668
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0005 0.0009 0.001
Echinococcus granulosus Immunoglobulin 0.0005 0.0013 0.0017
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.0078 0.0142
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Brugia malayi Isocitrate dehydrogenase 0.0008 0.0027 0.0018
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0008 0.0025 0.0042
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.009 0.0435 0.1274
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0069 0.0332 0.0668
Brugia malayi isocitrate dehydrogenase 0.0008 0.0027 0.0018
Chlamydia trachomatis protoporphyrinogen oxidase 0.0082 0.0394 0.9039
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Echinococcus granulosus CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0008 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0045 0.004
Echinococcus granulosus hemicentin 1 0.002 0.0088 0.0174
Loa Loa (eye worm) hypothetical protein 0.0114 0.0553 0.0549
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.009 0.0435 0.0426
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0655 0.3245 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.013 0.0373
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0005 0.0013 0.0017
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0075 0.0358 0.0731
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0082 0.0394 0.1189
Brugia malayi Immunoglobulin domain containing protein 0.0005 0.0013 0.0003
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0655 0.3245 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Echinococcus multilocularis 0.0082 0.0394 0.0806
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0388
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.013 0.0388
Schistosoma mansoni fk506 binding protein 0.009 0.0435 0.0882
Plasmodium vivax acyl-CoA synthetase, putative 0.0012 0.0045 0.011
Onchocerca volvulus 0.0114 0.0553 0.0544
Brugia malayi RNA recognition motif domain containing protein 0.0141 0.0687 0.0679
Echinococcus multilocularis hypothetical protein 0.0069 0.0332 0.0677
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0069 0.0332 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0078 0.0213
Loa Loa (eye worm) carboxylesterase 0.0114 0.0553 0.0549
Loa Loa (eye worm) hypothetical protein 0.0005 0.001 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0005 0.0013 0.0008
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.018 0.0171
Loa Loa (eye worm) RNA binding protein 0.0141 0.0687 0.0683
Schistosoma mansoni acetyl-CoA synthetase 0.0005 0.001 0.0001
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0069 0.0332 0.101
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0141 0.0687 0.0683
Echinococcus granulosus snurportin 1 0.0396 0.1958 0.4043
Leishmania major hypothetical protein, conserved 0.0008 0.0025 0.0077
Echinococcus multilocularis BC026374 protein (S09 family) 0.0114 0.0553 0.1136
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0015 0.0018
Schistosoma mansoni septate junction protein 0.0005 0.0013 0.0007
Entamoeba histolytica hypothetical protein 0.0006 0.0015 0.0018
Echinococcus multilocularis importin 5 0.0007 0.0022 0.0035
Onchocerca volvulus 0.0069 0.0332 0.0323
Loa Loa (eye worm) glutathione reductase 0.0083 0.0401 0.0396
Plasmodium falciparum metacaspase 1 0.0018 0.0078 0.0213
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0078 0.0213
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0005 0.001 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114 0.0553 0.1127
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0069 0.0332 0.0677
Echinococcus multilocularis caspase 8 0.0018 0.0078 0.0152
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.009 0.0435 0.0426
Onchocerca volvulus 0.2012 1 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.013 0.0374
Echinococcus granulosus protein tyrosine phosphatase n9 0.0069 0.0332 0.0677
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.013 0.2842
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0005 0.0013 0.0017
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1329
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.013 0.2572
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0008 0.0025 0.002
Echinococcus multilocularis roundabout 2 0.0005 0.0013 0.0017
Echinococcus granulosus netrin receptor unc 5 0.0005 0.0013 0.0017
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0069 0.0332 0.0677
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0005 0.0013 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0111 0.0211
Brugia malayi hypothetical protein 0.0069 0.0332 0.0323
Schistosoma mansoni hypothetical protein 0.009 0.0435 0.0882
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.009 0.0435 0.1301
Schistosoma mansoni immunophilin 0.0657 0.3254 0.6723
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0008 0.0025 0.0364
Echinococcus granulosus mitogen activated protein kinase 11 0.0633 0.3138 0.6485
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.002
Trichomonas vaginalis fk506 binding protein, putative 0.009 0.0435 0.1316
Brugia malayi TAR-binding protein 0.0141 0.0687 0.0679
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1081 0.5365 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0027 0.0047
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.013 0.0388
Trypanosoma brucei hypothetical protein, conserved 0.009 0.0435 0.1315
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.013 0.0357
Leishmania major fk506-binding protein 1-like protein 0.0655 0.3245 1
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0008 0.0025 0.0034
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0974 0.4836 1
Toxoplasma gondii HEAT repeat-containing protein 0.0037 0.0171 0.3806
Schistosoma mansoni hypothetical protein 0.0005 0.0013 0.0007
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0008 0.0025 0.0042
Loa Loa (eye worm) importin-beta domain-containing protein 0.0007 0.0022 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0687 0.1405
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.009 0.0435 0.1315
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0008 0.0025 0.0364
Echinococcus granulosus low density lipoprotein receptor ldl 0.0015 0.0062 0.012
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.009 0.0435 0.1315
Trypanosoma brucei importin beta-1 subunit, putative 0.0037 0.0171 0.05
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0008 0.0025 0.0048
Schistosoma mansoni netrin receptor unc5 0.0005 0.0013 0.0007
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0008 0.0025 0.0048
Mycobacterium ulcerans hypothetical protein 0.0016 0.0065 0.0095
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0005 0.0013 0.0017
Schistosoma mansoni BC026374 protein (S09 family) 0.0114 0.0553 0.1127
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0008 0.0025 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0025 0.0063
Onchocerca volvulus 0.0069 0.0332 0.0323
Brugia malayi hypothetical protein 0.0069 0.0332 0.0323
Schistosoma mansoni neuroglian 0.0005 0.0013 0.0007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.013 0.021
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0005 0.001 0.0016
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0396 0.1958 0.1954
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0005 0.001 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0687 0.1405
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0008 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0084
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0114 0.0553 0.1021
Echinococcus multilocularis CD36 class B scavenger receptor 0.0112 0.0543 0.1114
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.009 0.0435 0.043
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0065 0.0055
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0005 0.0009 0.0005
Echinococcus granulosus low density lipoprotein receptor ldl 0.0005 0.0013 0.0017
Onchocerca volvulus 0.0069 0.0332 0.0323
Echinococcus multilocularis thioredoxin glutathione reductase 0.0083 0.0401 0.0821
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0008 0.0025 0.0042
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0029 0.013 0.2838
Schistosoma mansoni neuroligin 3 (S09 family) 0.0114 0.0553 0.1127
Brugia malayi Protein-tyrosine phosphatase 0.0069 0.0332 0.0323
Plasmodium falciparum glutathione reductase 0.0029 0.013 0.0374
Onchocerca volvulus 0.0069 0.0332 0.0323
Onchocerca volvulus 0.0069 0.0332 0.0323
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0069 0.0332 0.0668
Brugia malayi Carboxylesterase family protein 0.0114 0.0553 0.0544
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0082 0.0394 0.1189
Leishmania major 4-coumarate:coa ligase-like protein 0.0016 0.0065 0.0199
Chlamydia trachomatis thioredoxin reductase 0.0008 0.0025 0.0364
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0005 0.0013 0.0007
Brugia malayi Thioredoxin reductase 0.0083 0.0401 0.0392
Brugia malayi Heparan sulfate 0.0005 0.0013 0.0003
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0008 0.0025 0.0047
Echinococcus granulosus glutamate synthase 0.0008 0.0025 0.0042
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0114 0.0553 0.1021
Echinococcus multilocularis protoporphyrinogen oxidase 0.0082 0.0394 0.0806
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0015 0.0141
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0324 0.1598 0.159
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0008 0.0025 0.0042
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0655 0.3245 0.5614
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0075 0.0358 0.0731
Schistosoma mansoni gliotactin 0.0114 0.0553 0.1127
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0005 0.001 0.0006
Echinococcus granulosus caspase 8 0.0018 0.0078 0.0152
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0082 0.0394 0.0806
Schistosoma mansoni cd36 antigen 0.0042 0.0197 0.0388
Schistosoma mansoni ran 0.0027 0.0123 0.0235
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0008 0.0025 0.0042
Echinococcus multilocularis acetylcholinesterase 0.0114 0.0553 0.1136
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0076 0.0149
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0065 0.0055
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0004 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0069 0.0332 0.0677
Schistosoma mansoni protein tyrosine phosphatase 0.0069 0.0332 0.0668
Loa Loa (eye worm) multidrug resistance protein 3 0.0005 0.0009 0.0004
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0069 0.0332 0.0677
Plasmodium vivax thioredoxin reductase, putative 0.0083 0.0401 0.1211
Schistosoma mansoni cell adhesion molecule 0.0005 0.0013 0.0007
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0078 0.0142
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0005 0.0013 0.0017
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.013 0.0374
Plasmodium falciparum glutathione reductase 0.0083 0.0401 0.1211
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0633 0.3138 0.9671
Mycobacterium ulcerans NADH dehydrogenase 0.0008 0.0025 0.0026
Loa Loa (eye worm) acetylcholinesterase 1 0.0114 0.0553 0.0549
Schistosoma mansoni cell adhesion molecule 0.0005 0.0013 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0082 0.0394 0.0724
Echinococcus granulosus Immunoglobulin 0.0005 0.0013 0.0017
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0008 0.0025 0.0047
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0069 0.0332 0.0994
Trypanosoma brucei NADH dehydrogenase 0.0008 0.0025 0.0047
Brugia malayi Immunoglobulin I-set domain containing protein 0.0005 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0045 0.004
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0008 0.0025 0.0042
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0655 0.3245 1
Trypanosoma brucei trypanothione reductase 0.0083 0.0401 0.121
Plasmodium falciparum transportin 0.0007 0.0022 0.0038
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0078 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0111 0.0211
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0687 0.1405
Echinococcus granulosus FK506 binding protein 2 0.009 0.0435 0.0891
Echinococcus multilocularis hemicentin 1 0.002 0.0088 0.0174
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Echinococcus multilocularis tar DNA binding protein 0.0141 0.0687 0.1413
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.006
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0015 0.0018
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0005 0.001 0.0006
Brugia malayi RNA, U transporter 1 0.0106 0.0512 0.0503
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0078 0.0227
Echinococcus granulosus roundabout 2 0.0005 0.0013 0.0017
Onchocerca volvulus 0.0015 0.0062 0.0053
Onchocerca volvulus 0.009 0.0437 0.0428
Brugia malayi hypothetical protein 0.0069 0.0332 0.0323
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.009 0.0435 0.1341
Echinococcus multilocularis lysosome membrane protein 2 0.0112 0.0543 0.1114
Brugia malayi P38 map kinase family protein 2 0.0633 0.3138 0.3131
Entamoeba histolytica acyl-CoA synthetase, putative 0.0016 0.0065 0.017
Mycobacterium ulcerans hypothetical protein 0.0008 0.0025 0.0026
Entamoeba histolytica acyl-CoA synthetase, putative 0.0016 0.0065 0.017
Echinococcus multilocularis peroxidasin 0.0005 0.0013 0.0017
Leishmania major tyrosine specific protein phosphatase, putative 0.0069 0.0332 0.1023
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0005 0.0009 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.027 0.0261
Mycobacterium ulcerans carboxylesterase, LipT 0.0999 0.4958 0.8587
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0083 0.0401 0.0737
Leishmania major p-glycoprotein e 0.0006 0.0015 0.0047
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0005 0.0009 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0069 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0042 0.0197 0.0192
Brugia malayi Carboxylesterase family protein 0.0114 0.0553 0.0544
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0069 0.0332 0.0677
Trichomonas vaginalis antibiotic synthetase, putative 0.0005 0.001 0.0001
Schistosoma mansoni basigin related 0.0005 0.0013 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.013 0.0388
Loa Loa (eye worm) hypothetical protein 0.0069 0.0332 0.0327
Schistosoma mansoni CD36-like class B scavenger receptor 0.0112 0.0543 0.1105
Entamoeba histolytica acyl-coA synthetase, putative 0.0016 0.0065 0.017
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0065 0.0095
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114 0.0553 0.1127
Trichomonas vaginalis Importin beta-1 subunit, putative 0.003 0.0136 0.0393
Schistosoma mansoni immunophilin 0.0657 0.3254 0.6723

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 0.003 mg kg-1 Analgesic activity at 1 min following injection at 1 mg/kg into the lateral tail vein of the rat (55 degree centigrade hot plate assay) ChEMBL. 1847432

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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