Detailed information for compound 290420

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 412.349 | Formula: C17H13N2NaO7S
  • H donors: 0 H acceptors: 7 LogP: 0.08 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CC(=O)OCC1=C(C(=O)[O-])N2C(S(=O)(=O)C1)/C(=C\c1ccccn1)/C2=O.[Na+]
  • InChi: 1S/C17H14N2O7S.Na/c1-2-13(20)26-8-10-9-27(24,25)16-12(7-11-5-3-4-6-18-11)15(21)19(16)14(10)17(22)23;/h2-7,16H,1,8-9H2,(H,22,23);/q;+1/p-1/b12-7-;
  • InChiKey: WJTYCLQDZFRNQT-OZLKFZLXSA-M  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Enterobacter cloacae Beta-lactamase class C Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0692 0.7984 1
Echinococcus multilocularis carboxylesterase 5A 0.0547 0.626 0.626
Loa Loa (eye worm) carboxylesterase 0.0092 0.0864 0.1082
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0178 0.1874 1
Echinococcus granulosus Niemann Pick C1 protein 0.0202 0.2163 0.2163
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0204 0.0204
Mycobacterium tuberculosis Carboxylesterase LipT 0.0092 0.0864 0.2817
Loa Loa (eye worm) hypothetical protein 0.0149 0.1536 0.1924
Brugia malayi conserved hypotetical protein 0.0126 0.1259 0.1577
Brugia malayi Cytochrome P450 family protein 0.0026 0.0076 0.0095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Brugia malayi beta-lactamase 0.0043 0.0283 0.0354
Brugia malayi hypothetical protein 0.0092 0.0864 0.1082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0046 0.0058
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0232 0.0232
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0142 0.1451 0.1451
Loa Loa (eye worm) hypothetical protein 0.0028 0.01 0.0125
Schistosoma mansoni hypothetical protein 0.0142 0.1451 0.1451
Loa Loa (eye worm) carboxylesterase 0.0092 0.0864 0.1082
Loa Loa (eye worm) hypothetical protein 0.0028 0.01 0.0125
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.026 0.026
Schistosoma mansoni lipoxygenase 0.0042 0.026 0.026
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Loa Loa (eye worm) solute carrier family 6 member 4 0.0164 0.1716 0.2149
Schistosoma mansoni hypothetical protein 0.007 0.0596 0.0596
Schistosoma mansoni coup transcription factor 0.0275 0.3028 0.3028
Entamoeba histolytica DNA topoisomerase II, putative 0.0063 0.052 0.43
Schistosoma mansoni lamin 0.0082 0.0745 0.0745
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.1148 0.1148
Loa Loa (eye worm) steroid hormone receptor 0.0275 0.3028 0.3793
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0076 0.0653
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0964 0.0964
Plasmodium falciparum transporter, putative 0.0028 0.0098 0.1855
Echinococcus granulosus sterol regulatory element binding protein 0.0101 0.0966 0.0966
Leishmania major cytochrome p450-like protein 0.0026 0.0076 0.0398
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.036 0.1915
Toxoplasma gondii hypothetical protein 0.0028 0.0098 0.0843
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0002 0.0006
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0122
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0046 0.0313 0.0314
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0354
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0152 0.1577 0.8411
Entamoeba histolytica hypothetical protein 0.0037 0.0204 0.169
Schistosoma mansoni hypothetical protein 0.0109 0.1063 0.1063
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0283 0.0919
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0005 0.0005
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0232 0.0232
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0066 0.0547 0.4521
Echinococcus multilocularis cpg binding protein 0.0064 0.0526 0.0526
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.1209 0.426
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0275 0.3028 0.3793
Brugia malayi hypothetical protein 0.0149 0.1536 0.1924
Echinococcus multilocularis protein dispatched 1 0.0107 0.1038 0.1038
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Brugia malayi Nuclear hormone receptor-like 1 0.0275 0.3028 0.3793
Echinococcus granulosus acetylcholinesterase 0.0547 0.626 0.626
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0964 0.7974
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0193 0.0242
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0122 0.1209 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0275 0.3028 0.3028
Echinococcus multilocularis lamin 0.0082 0.0745 0.0745
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0168 0.1455
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0149 0.1536 0.1536
Schistosoma mansoni intermediate filament proteins 0.0082 0.0745 0.0745
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0152 0.1577 0.8411
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0283 0.0919
Schistosoma mansoni zinc finger protein 0.0126 0.1259 0.1259
Schistosoma mansoni thyroid hormone receptor 0.0417 0.4712 0.4712
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0002 0.0006
Onchocerca volvulus 0.0042 0.026 0.0237
Brugia malayi nuclear receptor NHR-88 0.0126 0.1259 0.1577
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0275 0.3028 0.3793
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0323 0.0323
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0152 0.1577 0.8411
Echinococcus granulosus Nuclear hormone receptor HR96 0.0126 0.1259 0.1259
Loa Loa (eye worm) DR-78 0.0126 0.1259 0.1577
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0152 0.1577 0.5144
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0002 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0122 0.1209 0.1209
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0122
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0024 0.0046 0.0162
Echinococcus multilocularis neuroligin 0.0092 0.0864 0.0864
Brugia malayi Latrophilin receptor protein 2 0.0032 0.015 0.0189
Schistosoma mansoni cpg binding protein 0.0064 0.0526 0.0526
Loa Loa (eye worm) hypothetical protein 0.0164 0.1716 0.2149
Brugia malayi hypothetical protein 0.0042 0.026 0.0326
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0275 0.3028 0.3028
Echinococcus multilocularis sodium and chloride dependent glycine 0.0028 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0152 0.1577 0.5144
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0002 0.0014
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0122 0.1209 0.1209
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0024 0.0046 0.0856
Toxoplasma gondii DNA topoisomerase 2, putative 0.0063 0.052 0.4543
Brugia malayi hypothetical protein 0.0028 0.0098 0.0122
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Plasmodium falciparum DNA topoisomerase 2 0.0063 0.052 1
Giardia lamblia Rab geranylgeranyltransferase 0.0024 0.0046 0.0368
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0076 0.0243
Brugia malayi Carboxylesterase family protein 0.0092 0.0864 0.1082
Leishmania major cytochrome p450-like protein 0.0026 0.0076 0.0398
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0275 0.3028 0.3793
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.014 0.1431 0.1431
Echinococcus multilocularis slit 2 protein 0.0049 0.0343 0.0343
Leishmania major cytochrome p450-like protein 0.0036 0.0193 0.1024
Brugia malayi laminin alpha chain 0.0049 0.0343 0.043
Echinococcus granulosus expressed protein 0.0382 0.4305 0.4305
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0266 0.1413
Trypanosoma cruzi DNA topoisomerase II, putative 0.0057 0.0444 0.2363
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0354
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0024 0.0046 0.0162
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.036 0.1915
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.015 0.0189
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0359 0.1909
Trichomonas vaginalis CMGC family protein kinase 0.005 0.036 0.1269
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.036 0.036
Echinococcus multilocularis dnaJ subfamily B 0.0862 1 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0745 0.0934
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0275 0.3028 0.3793
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0323 0.0405
Trypanosoma brucei unspecified product 0.0035 0.0186 0.0985
Schistosoma mansoni polycystin 1-related 0.0042 0.026 0.026
Giardia lamblia DINP protein human, muc B family 0.0022 0.0023 0.0178
Brugia malayi tailless protein 0.0126 0.1259 0.1577
Brugia malayi small heat shock protein 0.0592 0.679 0.8505
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0843
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0138 0.0138
Giardia lamblia DNA topoisomerase II 0.0061 0.0487 0.4017
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0979 0.1227
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Onchocerca volvulus 0.0082 0.0745 0.0945
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.026 0.026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Onchocerca volvulus 0.0126 0.1259 0.1696
Brugia malayi Carboxylesterase family protein 0.0092 0.0864 0.1082
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.014 0.1431 0.7632
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0275 0.3028 0.3028
Mycobacterium tuberculosis Conserved protein 0.0043 0.0283 0.0919
Brugia malayi Carboxylesterase family protein 0.0547 0.626 0.7842
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0275 0.3028 0.3028
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0168 0.0168
Trichomonas vaginalis DNA topoisomerase II, putative 0.0063 0.052 0.1832
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0283 0.0919
Schistosoma mansoni hypothetical protein 0.0032 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Echinococcus granulosus expressed conserved protein 0.0095 0.0891 0.0891
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Trypanosoma cruzi squalene monooxygenase, putative 0.0167 0.1754 0.9359
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0178 0.1874 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.1209 0.6448
Schistosoma mansoni cell polarity protein 0.0049 0.0343 0.0343
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0126 0.1259 0.1259
Schistosoma mansoni nuclear hormone receptor 0.0126 0.1259 0.1259
Schistosoma mansoni cytochrome P450 0.0026 0.0076 0.0076
Echinococcus granulosus microtubule associated protein 2 0.0778 0.8997 0.8997
Leishmania major mitochondrial DNA topoisomerase II 0.005 0.0359 0.1909
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0283 0.0997
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Brugia malayi follicle stimulating hormone receptor 0.0245 0.2671 0.3346
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0023 0.0115
Schistosoma mansoni retinoic acid receptor RXR 0.0275 0.3028 0.3028
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0024 0.0046 0.0046
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0024 0.0046 0.0046
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0024 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0042 0.0262 0.0262
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0098 0.1855
Echinococcus granulosus sodium and chloride dependent glycine 0.0028 0.0098 0.0098
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0266 0.1413
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.1142 1
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0066 0.0547 0.1929
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0122 0.1209 0.1209
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0126 0.1259 0.1696
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0323 0.0405
Brugia malayi steroid hormone receptor 0.0275 0.3028 0.3793
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.026 0.026
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0275 0.3028 0.3793
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0005 0.0005
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0038 0.0221 0.0277
Schistosoma mansoni nuclear hormone receptor 0.0126 0.1259 0.1259
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0024 0.0046 0.0162
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0275 0.3028 0.3028
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0076 0.0398
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0193 0.1024
Brugia malayi beta-lactamase family protein 0.0043 0.0283 0.0354
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0063 0.052 0.052
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0024 0.0046 0.0162
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0537 0.0537
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0122 0.1209 0.1514
Echinococcus multilocularis lamin dm0 0.0082 0.0745 0.0745
Schistosoma mansoni hypothetical protein 0.0862 1 1
Trypanosoma brucei DNA topoisomerase ii 0.005 0.0359 0.1909
Loa Loa (eye worm) hypothetical protein 0.0024 0.0046 0.0058
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0024 0.0046 0.0856
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Leishmania major lanosterol synthase, putative 0.0148 0.1527 0.8147
Treponema pallidum sodium- and chloride- dependent transporter 0.0164 0.1716 1
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.014 0.1431 0.1792
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0283 0.0283
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0266 0.0938
Schistosoma mansoni ap endonuclease 0.002 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0152 0.1577 0.5144
Brugia malayi beta-lactamase family protein 0.0043 0.0283 0.0354
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0266 0.1413
Echinococcus granulosus cpg binding protein 0.0064 0.0526 0.0526
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0076 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0046 0.0237
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0152 0.1577 0.8411
Schistosoma mansoni patched 1 0.0101 0.0966 0.0966
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0024 0.0046 0.0058
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0275 0.3028 0.3028
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0076 0.0243
Schistosoma mansoni lamin 0.0082 0.0745 0.0745
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Mycobacterium ulcerans carboxylesterase, LipT 0.0092 0.0864 0.4606
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0204 0.0204
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0692 0.7984 0.7984
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0537 0.0673
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0122 0.1209 0.1209
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0178 0.1874 1
Brugia malayi laminin-like protein K08C7.3 precursor 0.0049 0.0343 0.043
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0354
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0028 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0149 0.1536 0.1924
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0092 0.0864 0.2817
Loa Loa (eye worm) hypothetical protein 0.014 0.1431 0.1792
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0046 0.0313 0.0314
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0152 0.1577 0.8411
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0228 0.2467 0.309
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0283 0.0919
Echinococcus multilocularis sodium and chloride dependent glycine 0.0028 0.0098 0.0098
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0126 0.1259 0.1259
Plasmodium falciparum DNA gyrase subunit B 0.0021 0.0015 0.0251
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0152 0.1577 0.5144
Echinococcus multilocularis acetylcholinesterase 0.0547 0.626 0.626
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0152 0.1577 0.8411
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0291 0.0365
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Brugia malayi Cytochrome P450 family protein 0.0036 0.0193 0.0242
Onchocerca volvulus 0.0126 0.1259 0.1696
Loa Loa (eye worm) hypothetical protein 0.0038 0.0221 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0275 0.3028 0.3793
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0126 0.1259 0.1259
Echinococcus multilocularis musashi 0.0082 0.0745 0.0745
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0275 0.3028 0.3028
Onchocerca volvulus 0.0092 0.0864 0.1119
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0275 0.3028 0.3793
Schistosoma mansoni hypothetical protein 0.0032 0.015 0.015
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0024 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.1209 0.426
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0015 0.0114
Onchocerca volvulus 0.0164 0.1716 0.2362
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0485 0.0608
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.1259 0.1259
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0275 0.3028 0.3793
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0283 0.0919
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0126 0.1259 0.1577
Trichomonas vaginalis spcc417.12 protein, putative 0.0092 0.0864 0.3045
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0076 0.0243
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.014 0.1431 0.7632
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.036 0.1915
Trypanosoma brucei squalene monooxygenase, putative 0.0167 0.1754 0.9359
Loa Loa (eye worm) hypothetical protein 0.0032 0.015 0.0189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0323 0.0323
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0164 0.1716 0.1716
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Brugia malayi polk-prov protein 0.0032 0.0145 0.0181
Schistosoma mansoni rab6-interacting 0.0042 0.026 0.026
Echinococcus multilocularis ubiquitin specific protease 41 0.0122 0.1209 0.1209
Echinococcus multilocularis Niemann Pick C1 protein 0.0202 0.2163 0.2163
Leishmania major geranylgeranyltransferase, putative 0.0024 0.0046 0.0237
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.015 0.015
Mycobacterium tuberculosis Conserved protein 0.0043 0.0283 0.0919
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.026 0.4989
Trichomonas vaginalis CMGC family protein kinase 0.005 0.036 0.1269
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.3063 1
Toxoplasma gondii hypothetical protein 0.0028 0.0098 0.0843
Loa Loa (eye worm) hypothetical protein 0.0122 0.1209 0.1514
Schistosoma mansoni niemann-pick C1 (NPC1) 0.016 0.1667 0.1667
Schistosoma mansoni sodium/chloride dependent transporter 0.0164 0.1716 0.1716
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.014 0.1431 0.1431
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0354
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Onchocerca volvulus 0.0042 0.026 0.0237
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.057 0.057
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0028 0.0098 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0275 0.3028 0.3793
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0076 0.0398
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0149 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0354
Chlamydia trachomatis DNA gyrase subunit B 0.0034 0.0176 1
Schistosoma mansoni nuclear receptor 0.0126 0.1259 0.1259
Trichomonas vaginalis CMGC family protein kinase 0.005 0.036 0.1269
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0537 0.0537
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0547 0.626 0.626
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0745 0.0934
Loa Loa (eye worm) hypothetical protein 0.0034 0.0168 0.021
Schistosoma mansoni ap endonuclease 0.002 0.0002 0.0002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0537 0.0673
Brugia malayi ecdysteroid receptor 0.0605 0.6949 0.8704
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0028 0.0098 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0005 0.0005
Brugia malayi nuclear hormone receptor 0.0275 0.3028 0.3793
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0168 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0046 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.036 0.3143
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Echinococcus multilocularis RUN 0.0042 0.026 0.026
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0076 0.0243
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0843
Schistosoma mansoni nuclear receptor 0.0126 0.1259 0.1259
Mycobacterium ulcerans DNA gyrase subunit B 0.0021 0.0015 0.007
Echinococcus multilocularis geminin 0.0536 0.6128 0.6128
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0537 0.0537
Loa Loa (eye worm) RNA binding protein 0.0065 0.0537 0.0673
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0145 0.0765
Plasmodium vivax DNA topoisomerase II, putative 0.0063 0.052 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0152 0.1577 0.5144
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0021 0.0015 0.0076
Loa Loa (eye worm) TOPoisomerase family member 0.0063 0.052 0.0651
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.014 0.1431 0.7632
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.026 0.026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0028 0.0098 0.0098
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0168 0.0168
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0275 0.3028 0.3028
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0275 0.3028 0.3028
Brugia malayi orphan nuclear receptor NR2E1 0.0126 0.1259 0.1577
Echinococcus multilocularis ecdysone induced protein 78C 0.0275 0.3028 0.3028
Brugia malayi RNA binding protein 0.0065 0.0537 0.0673
Mycobacterium ulcerans hypothetical protein 0.0043 0.0283 0.1502
Brugia malayi nuclear hormone receptor family member nhr-6 0.0126 0.1259 0.1577
Schistosoma mansoni rab6-interacting 0.0042 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0536 0.6128 0.6128
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0023 0.0115
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0283 0.5426
Schistosoma mansoni sodium-dependent amino acid transporter 0.0028 0.0098 0.0098
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0126 0.1259 0.1577
Brugia malayi Cytochrome P450 family protein 0.0036 0.0193 0.0242
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Echinococcus multilocularis expressed conserved protein 0.0095 0.0891 0.0891
Brugia malayi hypothetical protein 0.0126 0.1259 0.1577
Entamoeba histolytica hypothetical protein 0.0037 0.0204 0.169
Onchocerca volvulus 0.0043 0.0283 0.027
Trichomonas vaginalis esterase, putative 0.0043 0.0283 0.0997
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0275 0.3028 0.3028
Plasmodium vivax SET domain protein, putative 0.0034 0.0168 0.3203
Giardia lamblia Prenyltransferase 0.0024 0.0046 0.0368
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0021 0.0015 0.0043
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0266 0.0938
Schistosoma mansoni hypothetical protein 0.0037 0.0204 0.0204
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0193 0.1024
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0692 0.7984 0.7984
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0049 0.0343 0.043
Leishmania major hypothetical protein, conserved 0.0043 0.0283 0.1502
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Schistosoma mansoni lipoxygenase 0.0116 0.1148 0.1148
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0126 0.1259 0.1259
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0149 0.1536 0.1924
Brugia malayi ecdysone receptor 0.0126 0.1259 0.1577
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0275 0.3028 0.3028
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0024 0.0046 0.0237
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0001 0.0001
Echinococcus granulosus ubiquitin specific protease 41 0.0122 0.1209 0.1209
Trypanosoma cruzi DNA topoisomerase II, putative 0.0057 0.0444 0.2363
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0178 0.1874 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0092 0.0864 0.0864
Brugia malayi Carboxylesterase family protein 0.0547 0.626 0.7842
Echinococcus granulosus acetylcholinesterase 0.0547 0.626 0.626
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.057 0.057
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0964 0.1207
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.005 0.0359 0.1909
Echinococcus granulosus neurogenic locus notch protein 0.0049 0.0343 0.0343
Trypanosoma cruzi squalene monooxygenase, putative 0.0167 0.1754 0.9359
Trypanosoma cruzi protein farnesyltransferase, putative 0.0024 0.0046 0.0237
Brugia malayi CHE-14 protein 0.0101 0.0966 0.1209
Loa Loa (eye worm) hypothetical protein 0.0053 0.0396 0.0496
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0005 0.0005
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0024 0.0046 0.0058
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0266 0.1413
Loa Loa (eye worm) hypothetical protein 0.0042 0.026 0.0326
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0122
Echinococcus granulosus para nitrobenzyl esterase 0.0092 0.0864 0.0864
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0323 0.0323
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.026 0.4989
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0275 0.3028 0.3028
Schistosoma mansoni gliotactin 0.0092 0.0864 0.0864
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0275 0.3028 0.3793
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0126 0.1259 0.1259
Toxoplasma gondii ABC1 family protein 0.0043 0.0283 0.2465
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0092 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0283 0.1502
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0596 0.0746
Mycobacterium leprae Probable lipase LipE 0.0043 0.0283 0.1378
Loa Loa (eye worm) abnormal epIthelia family member 0.0049 0.0343 0.043
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0024 0.0046 0.0058
Brugia malayi TAR-binding protein 0.0065 0.0537 0.0673
Loa Loa (eye worm) serotonin transporter b 0.0164 0.1716 0.2149
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0745 0.0934
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0322 0.0404
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0023 0.007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0122
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0024 0.0046 0.0237
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0032 0.0145 0.0181
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0149 0.1536 0.1924
Loa Loa (eye worm) histone methyltransferase 0.002 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0354
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.057 0.3033
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0005 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.015 0.015
Schistosoma mansoni sodium/chloride dependent transporter 0.0028 0.0098 0.0098
Schistosoma mansoni BC026374 protein (S09 family) 0.0092 0.0864 0.0864
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0076 0.0243
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0028 0.0098 0.0098
Schistosoma mansoni memapsin-2 (A01 family) 0.0454 0.5151 0.5151
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0152 0.1577 0.5144
Onchocerca volvulus 0.0092 0.0864 0.1119
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0122 0.1209 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0964 0.0964
Schistosoma mansoni laminin gamma-3 chain 0.0049 0.0343 0.0343
Schistosoma mansoni DNA topoisomerase II 0.0063 0.052 0.052
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0002 0.0002
Onchocerca volvulus 0.0043 0.0283 0.027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0168 0.0168
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0024 0.0046 0.0046
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0537 0.0673
Loa Loa (eye worm) nuclear receptor NHR-67 0.0126 0.1259 0.1577
Mycobacterium ulcerans lipase LipD 0.0043 0.0283 0.1502
Leishmania major DNA polymerase kappa, putative 0.0022 0.0023 0.0115
Brugia malayi Carboxylesterase family protein 0.0092 0.0864 0.1082
Schistosoma mansoni loxhd1 0.0042 0.026 0.026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0275 0.3028 0.3793
Mycobacterium ulcerans oxidoreductase 0.0126 0.1267 0.676
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0283 0.1502
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0028 0.0098 0.5166
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0024 0.0046 0.0856
Loa Loa (eye worm) beta-lactamase 0.0043 0.0283 0.0354
Trypanosoma cruzi lanosterol synthase, putative 0.0172 0.1806 0.9637
Leishmania major DNA topoisomerase ii 0.0057 0.0444 0.2363
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0028 0.0098 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0323 0.0323
Echinococcus granulosus lamin 0.0082 0.0745 0.0745
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0149 0.1536 0.1536
Brugia malayi hypothetical protein 0.0149 0.1536 0.1924
Brugia malayi hypothetical protein 0.0042 0.026 0.0326
Entamoeba histolytica hypothetical protein 0.0037 0.0204 0.169
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0024 0.0046 0.0046
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0057 0.0444 0.2363
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0066 0.0547 0.1929
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0024 0.0046 0.0389
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0076 0.0243
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.036 0.0451
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.015 0.0189
Brugia malayi EGF-like domain containing protein 0.0049 0.0343 0.043
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0024 0.0046 0.0389
Trypanosoma brucei protein kinase, putative 0.005 0.036 0.1915
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0024 0.0046 0.0856
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0024 0.0046 0.0046
Brugia malayi hypothetical protein 0.0037 0.0204 0.0256
Trypanosoma brucei lanosterol synthase 0.0172 0.1806 0.9637
Echinococcus multilocularis protein patched 0.0101 0.0966 0.0966
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0063 0.052 0.052
Echinococcus granulosus sodium and chloride dependent glycine 0.0028 0.0098 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0275 0.3028 0.3793
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0275 0.3028 0.3793
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0145 0.0765
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0283 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.005 0.036 0.036
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.057 0.3033
Brugia malayi Steroid receptor seven-up type 2 0.0275 0.3028 0.3793
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0239 0.0239
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0275 0.3028 0.3028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0275 0.3028 0.3793
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0283 0.1502
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0186 0.0985
Brugia malayi Nuclear hormone receptor-like 1 0.0149 0.1536 0.1924
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0076 0.0243
Trichomonas vaginalis set domain proteins, putative 0.0259 0.2838 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0076 0.0243
Brugia malayi nuclear hormone receptor family member odr-7 0.0126 0.1259 0.1577
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0122 0.1209 0.1209
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.036 0.1915
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0024 0.0046 0.0389
Plasmodium falciparum amino acid transporter, putative 0.0028 0.0098 0.1855
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0024 0.0046 0.0381
Loa Loa (eye worm) hypothetical protein 0.0049 0.0343 0.043
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0283 0.0354
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0283 0.0997
Onchocerca volvulus Protein ultraspiracle homolog 0.0275 0.3028 0.4277
Onchocerca volvulus 0.0092 0.0864 0.1119
Echinococcus multilocularis pikachurin 0.0049 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0102 0.0979 0.1227
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0092 0.0864 0.3045
Echinococcus multilocularis thyroid hormone receptor alpha 0.0417 0.4712 0.4712
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.036 0.1915
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Brugia malayi Cytochrome P450 family protein 0.0047 0.0322 0.0404
Schistosoma mansoni microtubule-associated protein tau 0.0778 0.8997 0.8997
Onchocerca volvulus 0.0034 0.0168 0.0102
Echinococcus multilocularis para nitrobenzyl esterase 0.0092 0.0864 0.0864
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0122 0.1209 0.1209
Schistosoma mansoni hypothetical protein 0.0032 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0049 0.0343 0.043
Echinococcus multilocularis neurogenic locus notch protein 0.0049 0.0343 0.0343
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Loa Loa (eye worm) cytochrome P450 0.0026 0.0076 0.0095
Brugia malayi Nuclear hormone receptor E75 0.0126 0.1259 0.1577
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0515 0.5874 0.5874
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0024 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0149 0.1536 0.1924
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0537 0.0537
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0178 0.1874 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0024 0.0046 0.0162
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0283 0.0283
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0152 0.1577 0.8411
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0076 0.0398
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0149 0.1536 0.1536
Leishmania major farnesyltransferase beta subunit 0.0024 0.0046 0.0237
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0323 0.0323
Brugia malayi MAP kinase sur-1 0.005 0.036 0.0451
Loa Loa (eye worm) hypothetical protein 0.0081 0.0727 0.0911
Loa Loa (eye worm) hypothetical protein 0.0028 0.0098 0.0122
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.1209 0.6448
Echinococcus granulosus Protein patched homolog 1 0.0101 0.0966 0.0966
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.1209 0.426
Echinococcus multilocularis 0.0026 0.0076 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0275 0.3028 0.3793
Mycobacterium ulcerans beta-lactamase 0.0043 0.0283 0.1502
Plasmodium falciparum geranylgeranyltransferase, putative 0.0024 0.0046 0.0856
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0005 0.0007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.1259 0.1259
Echinococcus multilocularis GPCR, family 2 0.0032 0.015 0.015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.015 0.015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0168 0.0168
Echinococcus multilocularis serotonin transporter 0.0164 0.1716 0.1716
Loa Loa (eye worm) hypothetical protein 0.0275 0.3028 0.3793
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0126 0.1259 0.1259
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0024 0.0046 0.0162
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0193 0.1024
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0291 0.0365
Schistosoma mansoni hypothetical protein 0.0026 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0092 0.0864 0.1082
Loa Loa (eye worm) hypothetical protein 0.004 0.0239 0.03
Loa Loa (eye worm) hypothetical protein 0.0547 0.626 0.7842
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0168 0.0168
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0275 0.3028 0.3028
Loa Loa (eye worm) acetylcholinesterase 1 0.0547 0.626 0.7842
Schistosoma mansoni steroid hormone receptor ad4bp 0.0275 0.3028 0.3028
Loa Loa (eye worm) hypothetical protein 0.0042 0.026 0.0326
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0092 0.0864 0.0864
Brugia malayi intermediate filament protein 0.0082 0.0745 0.0934
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0152 0.1577 0.8411
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0204 0.0204
Echinococcus granulosus slit 2 protein 0.0049 0.0343 0.0343
Mycobacterium leprae putative cytochrome p450 0.0152 0.1577 1
Leishmania major squalene monooxygenase-like protein 0.0167 0.1754 0.9359
Schistosoma mansoni acetylcholinesterase 0.0092 0.0864 0.0864
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0076 0.0398
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0178 0.1874 0.6116
Echinococcus granulosus thyroid hormone receptor alpha 0.0126 0.1259 0.1259
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0692 0.7984 0.7984
Schistosoma mansoni hypothetical protein 0.0032 0.015 0.015
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0152 0.1577 0.8411
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0063 0.052 0.0651
Schistosoma mansoni neuroligin 3 (S09 family) 0.0092 0.0864 0.0864
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0043 0.0272 0.0341
Brugia malayi Probable DNA topoisomerase II 0.0063 0.052 0.0651
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0024 0.0046 0.0381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0275 0.3028 0.3793
Echinococcus multilocularis expressed protein 0.0382 0.4305 0.4305
Loa Loa (eye worm) doublecortin family protein 0.0042 0.026 0.0326
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0275 0.3028 0.3793
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0537 0.0537
Trypanosoma cruzi lanosterol synthase, putative 0.0172 0.1806 0.9637
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.014 0.1431 0.7632
Echinococcus granulosus neuroligin 0.0092 0.0864 0.0864
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0193 0.1024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0323 0.0323
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0164 0.1716 0.2149
Schistosoma mansoni hypothetical protein 0.0536 0.6128 0.6128
Plasmodium vivax geranylgeranyltransferase, putative 0.0024 0.0046 0.0856
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0003 0.0003
Schistosoma mansoni slit 0.0049 0.0343 0.0343
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.036 0.036
Echinococcus granulosus tar DNA binding protein 0.0065 0.0537 0.0537
Brugia malayi cytochrome P450 0.0026 0.0076 0.0095
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.1148 0.1148
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0966 0.3403
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0275 0.3028 0.3793
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0283 0.0919
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.057 0.3033
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.057 0.3033
Brugia malayi Pre-SET motif family protein 0.0034 0.0168 0.021
Echinococcus multilocularis acetylcholinesterase 0.0547 0.626 0.626
Schistosoma mansoni hypothetical protein 0.0042 0.0262 0.0262
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0283 0.0919
Plasmodium vivax amine transporter, putative 0.0028 0.0098 0.1855
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.036 0.036
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0193 0.0242
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0537 0.0537
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0024 0.0046 0.0381
Onchocerca volvulus 0.0259 0.2838 0.3999
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.1267 0.4134
Loa Loa (eye worm) norepinephrine transporter 0.0164 0.1716 0.2149
Loa Loa (eye worm) hypothetical protein 0.0101 0.0966 0.1209
Onchocerca volvulus Bile acid receptor homolog 0.0605 0.6949 1
Brugia malayi hypothetical protein 0.0126 0.1259 0.1577
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0152 0.1577 0.8411
Giardia lamblia Kinase, CMGC MAPK 0.005 0.036 0.297
Entamoeba histolytica hypothetical protein 0.0037 0.0204 0.169
Mycobacterium tuberculosis Conserved protein 0.0043 0.0283 0.0919
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0283 0.0997
Schistosoma mansoni sodium/chloride dependent transporter 0.0028 0.0103 0.0103
Echinococcus granulosus carboxylesterase 5A 0.0547 0.626 0.626
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0046 0.0313 0.0314
Brugia malayi nuclear receptor RXR 0.0149 0.1536 0.1924
Schistosoma mansoni hypothetical protein 0.0042 0.0262 0.0262
Echinococcus granulosus GPCR family 2 0.0032 0.015 0.015
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0002 0.0002
Echinococcus multilocularis nuclear receptor nhr 48 0.0126 0.1259 0.1259
Echinococcus granulosus dna polymerase kappa 0.0042 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0042 0.026 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Echinococcus granulosus FTZ F1 alpha 0.0275 0.3028 0.3028
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0024 0.0046 0.0058
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0024 0.0046 0.0162
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0028 0.0098 0.0098
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0043 0.0272 0.0341
Loa Loa (eye worm) hypothetical protein 0.0547 0.626 0.7842
Brugia malayi Nuclear hormone receptor-like 1 0.0149 0.1536 0.1924
Loa Loa (eye worm) hypothetical protein 0.0592 0.679 0.8505
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0024 0.0046 0.0162
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0239 0.0239
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0283 0.0997
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0275 0.3028 0.3028
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0021 0.0015 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0152 0.1577 0.5144
Brugia malayi photoreceptor-specific nuclear receptor 0.0275 0.3028 0.3793
Brugia malayi nuclear receptor NHR-67 0.0126 0.1259 0.1577
Loa Loa (eye worm) carboxylesterase 0.0547 0.626 0.7842
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0275 0.3028 0.3028
Brugia malayi nuclear receptor RXR 0.0126 0.1259 0.1577
Echinococcus granulosus mitogen activated protein kinase 0.005 0.036 0.036
Echinococcus granulosus nuclear receptor nhr 48 0.0126 0.1259 0.1259
Brugia malayi Carboxylesterase family protein 0.0092 0.0864 0.1082
Schistosoma mansoni cpg binding protein 0.0064 0.0526 0.0526
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0066 0.0547 0.1929
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.1305 0.1305
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0028 0.0098 0.0098
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.014 0.1431 0.1431
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0024 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0164 0.1716 0.2149
Loa Loa (eye worm) hypothetical protein 0.0101 0.0964 0.1207
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0152 0.1577 0.5144
Trypanosoma cruzi protein farnesyltransferase, putative 0.0024 0.0046 0.0237
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0092 0.0864 0.0864
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.1209 0.6448
Onchocerca volvulus 0.0275 0.3028 0.4277
Onchocerca volvulus 0.0082 0.0745 0.0945
Echinococcus multilocularis sterol regulatory element binding protein 0.0101 0.0966 0.0966
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0283 0.1378
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0122
Echinococcus multilocularis BC026374 protein (S09 family) 0.0092 0.0864 0.0864
Echinococcus granulosus serotonin transporter 0.0164 0.1716 0.1716
Echinococcus granulosus BC026374 protein S09 family 0.0092 0.0864 0.0864
Schistosoma mansoni nuclear hormone receptor 0.0275 0.3028 0.3028
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0028 0.0098 0.0098
Echinococcus granulosus ecdysone induced protein 78C 0.0275 0.3028 0.3028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0283 0.0283
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0057 0.0444 0.2363
Echinococcus granulosus pikachurin 0.0049 0.0343 0.0343
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0745 0.0934
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.057 0.0713
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0152 0.1577 0.5144
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0024 0.0046 0.0237
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0095 0.0896 0.292
Echinococcus granulosus Nuclear hormone receptor HR96 0.0126 0.1259 0.1259
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.057 0.057
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0283 0.0997
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0152 0.1577 0.8411
Schistosoma mansoni hypothetical protein 0.0042 0.0262 0.0262
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0193 0.0242
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.014 0.1431 0.7632
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0275 0.3028 0.3028
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0283 0.1502
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0692 0.7984 1
Onchocerca volvulus 0.0092 0.0864 0.1119
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0245 0.2671 0.3346
Schistosoma mansoni RAR-like nuclear receptor 0.0275 0.3028 0.3028
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0979 0.1227
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0152 0.1577 0.8411
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0283 0.1502
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0152 0.1577 0.8411
Loa Loa (eye worm) hypothetical protein 0.0149 0.1536 0.1924
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.026 0.026
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0275 0.3028 0.4277
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0076 0.0243
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0028 0.0098 0.0843
Schistosoma mansoni thyroid hormone receptor 0.0417 0.4712 0.4712
Onchocerca volvulus 0.0092 0.0864 0.1119
Loa Loa (eye worm) nuclear hormone receptor 0.0126 0.1259 0.1577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0275 0.3028 0.3793
Brugia malayi Nuclear hormone receptor E75 0.0126 0.1259 0.1577
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0142 0.1451 0.1451
Brugia malayi nuclear hormone receptor 0.0126 0.1259 0.1577
Schistosoma mansoni nuclear receptor nhr-48 0.0126 0.1259 0.1259
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0101 0.0966 0.1209
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0024 0.0046 0.0058
Echinococcus multilocularis FTZ F1 alpha 0.0275 0.3028 0.3028
Loa Loa (eye worm) hypothetical protein 0.0164 0.1716 0.2149
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0979 0.1227
Onchocerca volvulus 0.0043 0.0283 0.027
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0049 0.0343 0.0343
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0005 0.0007
Brugia malayi Doublecortin family protein 0.0042 0.026 0.0326
Onchocerca volvulus 0.0061 0.0485 0.0566
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Echinococcus granulosus RUN 0.0042 0.026 0.026
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.057 0.4711
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0024 0.0046 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Loa Loa (eye worm) hypothetical protein 0.007 0.0596 0.0746
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0152 0.1577 0.8411
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0063 0.052 0.0651
Echinococcus granulosus geminin 0.0536 0.6128 0.6128
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.036 0.1915
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0275 0.3028 0.3793
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0152 0.1577 0.5144
Loa Loa (eye worm) hypothetical protein 0.0049 0.0343 0.043
Echinococcus granulosus lamin dm0 0.0082 0.0745 0.0745
Schistosoma mansoni cpg binding protein 0.0061 0.0485 0.0485
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0152 0.1577 0.8411
Brugia malayi nuclear receptor NHR-88 0.0275 0.3028 0.3793
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.057 0.0713
Loa Loa (eye worm) hypothetical protein 0.0605 0.6949 0.8704
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.036 0.1915
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0275 0.3028 0.3028
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0266 0.1413
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0122 0.1209 0.6448
Echinococcus granulosus intermediate filament protein 0.0082 0.0745 0.0745
Brugia malayi Pre-SET motif family protein 0.0228 0.2467 0.309
Loa Loa (eye worm) hypothetical protein 0.0126 0.1259 0.1577
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0092 0.0864 0.0864
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0126 0.1259 0.1696
Echinococcus multilocularis microtubule associated protein 2 0.0778 0.8997 0.8997
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0092 0.0864 0.2817
Brugia malayi CXXC zinc finger family protein 0.0061 0.0485 0.0608
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0275 0.3028 0.3028
Plasmodium vivax DNA gyrase subunit B, putative 0.0021 0.0015 0.0251
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0152 0.1577 0.8411
Trichomonas vaginalis CMGC family protein kinase 0.005 0.036 0.1269

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) 0 uM The compound was evaluated for inhibition against Class A TEM-1 beta-lactamase derived from Enterobacter cloacae; Not tested ChEMBL. 10853646
IC50 (binding) = 0.1 uM Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99 ChEMBL. 10853646
IC50 (binding) = 0.1 uM Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99 ChEMBL. 10853646
IC50 (binding) = 0.9 uM Inhibition of GC1 extended spectrum class C beta-lactamase ChEMBL. 10853646
IC50 (binding) = 0.9 uM Inhibition of GC1 extended spectrum class C beta-lactamase ChEMBL. 10853646
IC50 (binding) = 110 uM Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1 ChEMBL. 10853646
IC50 (binding) = 110 uM Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1 ChEMBL. 10853646

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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