Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 100 uM | In vitro antiviral activity against adeno virus using plaque reduction assay. | ChEMBL. | 6854592 |
ED50 (functional) | > 100 uM | In vitro cytotoxicity against human D-38 cells. | ChEMBL. | 6854592 |
ED50 (functional) | > 100 uM | in vitro cytotoxicity against mouse L cells. | ChEMBL. | 6854592 |
ED50 (functional) | > 100 uM | in vitro cytotoxicity against mouse L cells. | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Vibrio cholerae | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Pasteurella multocida | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Salmonella typhimurium | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Salmonella typhi | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Shigella flexneri | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Escherichia coli | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Serratia marcescens | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Klebsiella pneumoniae | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Enterobacter aerogenes | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Citrobacter freundii | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Proteus vulgaris | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Proteus mirabilis | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Pseudomonas aeruginosa | ChEMBL. | 6854592 |
MIC (functional) | > 200 uM | Minimum inhibitory concentration against Escherichia coli | ChEMBL. | 6854592 |
MIC (functional) | > 400 uM | In vitro minimum inhibitory concentration against Staphylococcus aureus | ChEMBL. | 6854592 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.