Detailed information for compound 30151

Basic information

Technical information
  • TDR Targets ID: 30151
  • Name: 1-[6-(4-ethoxyanilino)-9-propan-2-ylpurin-2-y l]-3-methylpent-1-yn-3-ol
  • MW: 393.482 | Formula: C22H27N5O2
  • H donors: 2 H acceptors: 4 LogP: 3.63 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)Nc1nc(C#CC(CC)(O)C)nc2c1ncn2C(C)C
  • InChi: 1S/C22H27N5O2/c1-6-22(5,28)13-12-18-25-20(19-21(26-18)27(14-23-19)15(3)4)24-16-8-10-17(11-9-16)29-7-2/h8-11,14-15,28H,6-7H2,1-5H3,(H,24,25,26)
  • InChiKey: FVOYXCNJIASCPE-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-[6-(4-ethoxyanilino)-9-isopropyl-purin-2-yl]-3-methyl-pent-1-yn-3-ol
  • 1-[6-(4-ethoxyanilino)-9-isopropyl-2-purinyl]-3-methyl-1-pentyn-3-ol
  • 1-[6-[(4-ethoxyphenyl)amino]-9-propan-2-yl-purin-2-yl]-3-methyl-pent-1-yn-3-ol
  • 1-[9-isopropyl-6-(p-phenetidino)purin-2-yl]-3-methyl-pent-1-yn-3-ol
  • 1-[6-[(4-ethoxyphenyl)amino]-9-propan-2-ylpurin-2-yl]-3-methylpent-1-yn-3-ol
  • 1-[6-[(4-ethoxyphenyl)amino]-9-isopropyl-purin-2-yl]-3-methyl-pent-1-yn-3-ol
  • 1-[6-[(4-ethoxyphenyl)amino]-9-isopropyl-2-purinyl]-3-methylpent-1-yn-3-ol
  • C-2 alkynylated purine deriv. 5c

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin B1 References
Homo sapiens cyclin-dependent kinase 5 Starlite/ChEMBL References
Homo sapiens cyclin B3 Starlite/ChEMBL References
Homo sapiens cyclin B2 Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 3 References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei gambiense cyclin 6,mitotic cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) cyclin domain-containing protein Get druggable targets OG5_134175 All targets in OG5_134175
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum IPR002155,Thiolase,domain-containing Get druggable targets OG5_134175 All targets in OG5_134175
Trypanosoma brucei mitotic cyclin 6 Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania mexicana CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus granulosus cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis mitotic cyclin-CYC2 Get druggable targets OG5_126649 All targets in OG5_126649
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis G2:mitotic specific cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Leishmania infantum cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Onchocerca volvulus Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus G2:mitotic specific cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K05868 cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani CYC2-like cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma mansoni cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia G2/mitotic-specific cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K05868 cyclin B, putative Get druggable targets OG5_134175 All targets in OG5_134175
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin A, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense mitotic cyclin 6 Get druggable targets OG5_126649 All targets in OG5_126649
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans likely B-type cyclin similar to S. cerevisiae CLB4 (YLR210W) and CLB3 (YDL155W) involved in G1/S transition Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_134175 All targets in OG5_134175
Candida albicans likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma congolense Cyclin, N-terminal domain/Cyclin, C-terminal domain containing protein, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania braziliensis cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma mansoni cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi CYC2-like cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 5 260 aa 307 aa 28.3 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0205 0.0954
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0267 0.1333 0.6234
Schistosoma mansoni atypical protein kinase C 0.0048 0.0174 0.024
Echinococcus granulosus protein jagged 2 0.0026 0.0062 0.0085
Echinococcus multilocularis myotubularin protein 13 0.0019 0.0023 0.0032
Loa Loa (eye worm) raf kinase 0.0019 0.0023 0.0093
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0016 0.0063
Loa Loa (eye worm) hypothetical protein 0.0079 0.0341 0.1374
Trypanosoma cruzi cyclin, putative 0.0124 0.0579 0.0727
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.005 0.0189 0.067
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0096 0.0427 0.0587
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0046 0.0166 0.0228
Trypanosoma cruzi cdc2-related kinase 3 0.0105 0.0478 0.06
Echinococcus granulosus microtubule associated protein 2 0.1391 0.727 1
Echinococcus multilocularis protein jagged 1 0.0026 0.0062 0.0085
Plasmodium vivax copper-transporting ATPase, putative 0.0079 0.0341 0.1571
Trypanosoma cruzi CYC2-like cyclin, putative 0.0124 0.0579 0.0727
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0032 0.0092 0.0127
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0098 0.0438 0.2047
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0079 0.0341 0.0336
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0205 0.0254
Brugia malayi Cathepsin L-like precursor 0.0046 0.0166 0.0666
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0127 0.0595 0.0818
Trypanosoma cruzi cysteine proteinase, putative 0.0037 0.0116 0.0142
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0079 0.0341 0.2537
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0016 0.0088
Brugia malayi Heterochromatin protein 1 0.0074 0.0311 0.1252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0458 0.1845
Leishmania major cathepsin L-like protease 0.01 0.0451 0.2095
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0474 0.0654
Loa Loa (eye worm) calcium ATPase 0.0043 0.0152 0.0611
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.002 0.0085
Trypanosoma brucei calcium-translocating P-type ATPase 0.0376 0.1911 1
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0029 0.0073 0.0295
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0478 0.2233
Loa Loa (eye worm) cyclin C 0.0016 0.0004 0.0016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0016 0.0063
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.002 0.0029 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0092 0.0371
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0035 0.0104 0.0755
Brugia malayi Protein kinase domain containing protein 0.0029 0.0073 0.0295
Schistosoma mansoni Smad4 0.0033 0.0097 0.0133
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0149 0.0205
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0166 0.1215
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0342 0.1572
Leishmania major DNA polymerase kappa, putative 0.003 0.0082 0.0367
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0079 0.0341 0.1374
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0374
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1907 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0077 0.0329 0.0453
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0213 0.1046 0.1317
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Schistosoma mansoni ATPase 0.0419 0.2137 0.2939
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0007 0.001
Schistosoma mansoni cyclins 0.0064 0.0262 0.036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Echinococcus multilocularis phosphoserine phosphatase 0.0048 0.0174 0.0239
Onchocerca volvulus 0.0105 0.0479 0.3766
Leishmania major cathepsin L-like protease 0.0046 0.0166 0.0757
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0331
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0091
Echinococcus multilocularis neural cadherin 0.0026 0.0062 0.0085
Schistosoma mansoni cation-transporting atpase worm 0.0079 0.0341 0.0469
Brugia malayi Ras association domain family 1 isoform A 0.0019 0.0023 0.0093
Brugia malayi chromobox protein homolog 3 0.0041 0.014 0.0564
Trichomonas vaginalis cyclin B, putative 0.0124 0.0579 0.2703
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0082 0.0365
Echinococcus multilocularis cathepsin L cysteine protease 0.0046 0.0166 0.0228
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0037 0.0118
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0062 0.0248
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0452 0.3368
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0482
Loa Loa (eye worm) hypothetical protein 0.0082 0.0355 0.1428
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0016 0.0054
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Giardia lamblia Cathepsin L precursor 0.0018 0.0016 0.0088
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0205 0.0282
Onchocerca volvulus 0.0032 0.0092 0.0725
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0376 0.1911 0.7694
Entamoeba histolytica hypothetical protein 0.0077 0.0327 0.2433
Echinococcus granulosus protein kinase c eta type 0.0019 0.0023 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.002 0.0085
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0224 0.1108 0.1524
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0205 0.1513
Brugia malayi MH1 domain containing protein 0.0018 0.0019 0.0075
Echinococcus multilocularis cyclin G2 0.0016 0.0004 0.0005
Onchocerca volvulus 0.0046 0.0166 0.1302
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0082 0.0365
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0073 0.0101
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Echinococcus multilocularis cysteine protease 0.0046 0.0166 0.0228
Brugia malayi Cathepsin L-like precursor 0.0019 0.0023 0.0091
Brugia malayi Cyclin, N-terminal domain containing protein 0.0199 0.0972 0.3912
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0536 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.0278 0.1438
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0261
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Loa Loa (eye worm) glutathione reductase 0.0046 0.0164 0.066
Onchocerca volvulus Dual oxidase homolog 0.0082 0.0354 0.2785
Echinococcus multilocularis fibropellin Ia 0.0026 0.0062 0.0085
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0096 0.0427 0.0587
Giardia lamblia Cathepsin L precursor 0.0018 0.0016 0.0088
Giardia lamblia Hypothetical protein 0.0018 0.0016 0.0088
Brugia malayi CHE-14 protein 0.0043 0.0149 0.0601
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0032 0.0092 0.0371
Echinococcus multilocularis cation transporting atpase worm 0.0079 0.0341 0.0469
Brugia malayi protein kinase C II. 0.005 0.0187 0.0754
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.0043 0.0152 0.1111
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0021 0.0034 0.0139
Echinococcus multilocularis peroxidasin 0.0082 0.0354 0.0487
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0261
Trichomonas vaginalis cyclins, putative 0.0124 0.0579 0.2703
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Onchocerca volvulus 0.0046 0.0166 0.1302
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0149 0.0205
Trypanosoma cruzi cation-transporting ATPase, putative 0.0079 0.0341 0.0427
Leishmania major cathepsin L-like protease 0.0046 0.0166 0.0757
Schistosoma mansoni type V p-type atpase isoform 0.0079 0.0341 0.0469
Brugia malayi Cathepsin L-like precursor 0.0046 0.0166 0.0666
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0012 0.0027
Echinococcus multilocularis Diacylglycerol kinase theta 0.0019 0.0023 0.0032
Entamoeba histolytica protein kinase, putative 0.0029 0.0073 0.0521
Echinococcus multilocularis protein patched 0.0043 0.0149 0.0205
Schistosoma mansoni notch 0.0026 0.0062 0.0085
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0468
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0016 0.0054
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0468
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0067
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0092 0.0126
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0474 0.0654
Echinococcus multilocularis serine threonine protein kinase 0.0108 0.0494 0.0679
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0016 0.0054
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0079 0.0341 0.1223
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0105 0.0479 0.0658
Onchocerca volvulus 0.0032 0.0092 0.0725
Plasmodium falciparum cysteine proteinase falcipain 1 0.0037 0.0116 0.0523
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0007 0.0028
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0311 0.1252
Brugia malayi MH1 domain containing protein 0.0033 0.0097 0.0389
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Trichomonas vaginalis cation-transporting ATPase, putative 0.0032 0.0089 0.0412
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 1
Brugia malayi glutathione reductase 0.0046 0.0164 0.066
Echinococcus granulosus protein jagged 1 0.0026 0.0062 0.0085
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0035 0.0104 0.042
Giardia lamblia Kinase, CMGC CDK 0.0105 0.0478 0.3567
Schistosoma mansoni jun-related protein 0.0068 0.0283 0.039
Trichomonas vaginalis cyclins, putative 0.0016 0.0004 0.0012
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Plasmodium falciparum cation-transporting ATPase 1 0.0032 0.0089 0.0398
Brugia malayi calcium ATPase 0.0116 0.0536 0.2158
Echinococcus granulosus calcium transporting atpase 0.0376 0.1911 0.2629
Loa Loa (eye worm) hypothetical protein 0.0069 0.0289 0.1162
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0094 0.0421 0.1513
Brugia malayi Animal haem peroxidase family protein 0.0082 0.0354 0.1425
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0079 0.0341 0.0469
Echinococcus granulosus cyclin y 0.0016 0.0004 0.0005
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0094 0.0419 0.1956
Echinococcus granulosus cation transporting ATPase 13A3 0.0079 0.0341 0.0469
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0082 0.0113
Brugia malayi RhoGEF domain containing protein 0.0019 0.0023 0.0093
Treponema pallidum cation-transporting ATPase, P-type 0.0079 0.0341 0.0336
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Trichomonas vaginalis cyclins, putative 0.0124 0.0579 0.2703
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0004 0.0016
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0224 0.1108 0.4001
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0007 0.0004
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Giardia lamblia Cathepsin L-like protease 0.0018 0.0016 0.0088
Echinococcus granulosus NDR protein kinase 0.0029 0.0073 0.0101
Entamoeba histolytica cell division protein kinase 2, putative 0.0105 0.0478 0.3567
Schistosoma mansoni vav2 0.0019 0.0023 0.0032
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0016 0.0054
Entamoeba histolytica protein kinase, putative 0.0029 0.0073 0.0521
Plasmodium vivax vivapain-1 0.0037 0.0116 0.0523
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0035 0.0104 0.0471
Brugia malayi Cation transporter family protein 0.0032 0.0092 0.0371
Schistosoma mansoni acetylcholine receptor-related 0.0015 0 0.0001
Giardia lamblia Cysteine protease 0.0018 0.0016 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0098 0.0438 0.0605
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0438 0.2278
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0422 0.2151 0.7783
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0016 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0116 0.0142
Brugia malayi Pleckstrin Homology Domain 0.0019 0.0023 0.0093
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0007 0.0014
Onchocerca volvulus Chorion peroxidase homolog 0.0082 0.0354 0.2785
Leishmania major cathepsin L-like protease 0.01 0.0451 0.2095
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0079 0.0341 0.0469
Loa Loa (eye worm) hypothetical protein 0.01 0.0452 0.1818
Echinococcus granulosus cation transporting ATPase 13A1 0.0079 0.0341 0.0469
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0342 0.0427
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0422 0.2151 0.2959
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0016 0.0054
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0267 0.1333 0.697
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.004 0.0167
Echinococcus granulosus glycine receptor subunit beta 0.0032 0.0092 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0595 0.0818
Echinococcus granulosus cyclins 0.0064 0.0262 0.036
Plasmodium vivax P-type ATPase, putative 0.0032 0.0089 0.0398
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0032 0.0089 0.0412
Entamoeba histolytica hypothetical protein 0.0017 0.0014 0.0073
Echinococcus granulosus geminin 0.1217 0.6354 0.8739
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063
Onchocerca volvulus Huntingtin homolog 0.0125 0.0581 0.4572
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0094 0.0419 0.1956
Loa Loa (eye worm) hypothetical protein 0.0125 0.0581 0.2339
Loa Loa (eye worm) hypothetical protein 0.0122 0.0569 0.229
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0438 0.0433
Giardia lamblia Cyclin A 0.0064 0.0262 0.1939
Schistosoma mansoni cyclin G2 0.0016 0.0004 0.0005
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0096 0.0427 0.0587
Loa Loa (eye worm) cyclin domain-containing protein 0.0199 0.0972 0.3912
Loa Loa (eye worm) ACC-1 protein 0.0032 0.0092 0.0371
Brugia malayi hypothetical protein 0.0015 0 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0016 0.0063
Echinococcus multilocularis cathepsin L 0.0018 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0096 0.0427 0.1718
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0267 0.1333 0.1681
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0019 0.0023 0.0091
Giardia lamblia Kinase, CMGC CDK 0.0105 0.0478 0.3567
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0019 0.0023 0.0093
Plasmodium vivax protein kinase Crk2 0.0105 0.0478 0.2208
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0152 0.0728 0.2929
Trichomonas vaginalis cyclins, putative 0.0075 0.0321 0.1496
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0007 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.01 0.0451 0.0565
Brugia malayi hypothetical protein 0.0015 0 0.0002
Entamoeba histolytica cysteine proteinase 2 0.0037 0.0116 0.0845
Loa Loa (eye worm) animal heme peroxidase 0.0082 0.0354 0.1425
Echinococcus granulosus cyclin B3 1 0.0064 0.0262 0.036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0002
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0035 0.0104 0.0127
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0206 0.0731
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0016 0.0054
Schistosoma mansoni hypothetical protein 0.0032 0.0092 0.0126
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.002 0.0085
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0032 0.0092 0.0371
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0035 0.0104 0.0755
Echinococcus multilocularis cpg binding protein 0.003 0.008 0.011
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0017 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0108 0.0494 0.1989
Brugia malayi Protein kinase domain containing protein 0.0029 0.0073 0.0295
Loa Loa (eye worm) hypothetical protein 0.0133 0.0626 0.2522
Echinococcus granulosus nAChR subunit 0.0017 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0133 0.0626 0.2522
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0452 0.0621
Trichomonas vaginalis C-MYB, putative 0.0094 0.0419 0.1956
Brugia malayi Protein kinase domain containing protein 0.0105 0.0478 0.1925
Schistosoma mansoni rac gtpase activating protein 0.0019 0.0023 0.0032
Echinococcus granulosus phospholipid transporting atpase ih 0.0035 0.0104 0.0144
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0016
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Echinococcus granulosus Na:K ATPase alpha subunit 0.021 0.1034 0.1422
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0079 0.0341 0.0336
Schistosoma mansoni notch 0.0026 0.0062 0.0085
Echinococcus granulosus cyclins 0.0064 0.0262 0.036
Schistosoma mansoni cyclin l 0.0016 0.0004 0.0005
Schistosoma mansoni phospholipid-transporting atpase 1 (aminophospholipid flippase 1) 0.0032 0.0089 0.0123
Echinococcus granulosus delta-like protein 1 0.0026 0.0062 0.0085
Schistosoma mansoni cyclin B3 0.0199 0.0972 0.1336
Loa Loa (eye worm) hypothetical protein 0.0128 0.0597 0.2402
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0419 0.2137 0.2696
Leishmania major DNA polymerase eta, putative 0.0122 0.0569 0.2649
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Toxoplasma gondii P-type ATPase of unknown pump specificity (type V) protein 0.0032 0.0089 0.031
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0016 0.0054
Onchocerca volvulus Cathepsin L homolog 0.0046 0.0166 0.1302
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0166 0.1215
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0084 0.0365 0.1471
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0017 0.0014 0.0055
Echinococcus granulosus sodium channel protein 0.0155 0.0743 0.1023
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0082 0.0411
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0016 0.0055
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063
Echinococcus multilocularis nAChR subunit 0.0017 0.0014 0.0019
Trichomonas vaginalis cation-transporting ATPase, putative 0.0156 0.0746 0.3487
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0006 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Loa Loa (eye worm) CYL-1 protein 0.0016 0.0004 0.0016
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0438 0.0433
Loa Loa (eye worm) hypothetical protein 0.0103 0.0467 0.1879
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0224 0.1108 0.1524
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0094 0.0419 0.3122
Leishmania major cathepsin L-like protease 0.01 0.0451 0.2095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0082 0.0411
Schistosoma mansoni protein kinase C mu 0.0021 0.0034 0.0047
Schistosoma mansoni chromobox protein 0.0074 0.0311 0.0428
Echinococcus multilocularis geminin 0.1217 0.6354 0.8739
Loa Loa (eye worm) hypothetical protein 0.0079 0.0341 0.1374
Schistosoma mansoni hypothetical protein 0.0032 0.0092 0.0126
Schistosoma mansoni hypothetical protein 0.0069 0.0289 0.0397
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0205 0.0954
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0017 0.0014 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0016 0.0067
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0006 0.001
Toxoplasma gondii cathepsin CPC2 0.0018 0.0016 0.0042
Brugia malayi Protein kinase domain containing protein 0.0021 0.0034 0.0139
Echinococcus multilocularis protein jagged 2 0.0026 0.0062 0.0085
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0438 0.2278
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0019 0.0023 0.0032
Schistosoma mansoni cpg binding protein 0.0028 0.0072 0.0099
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0029 0.0073 0.0101
Echinococcus multilocularis cyclin t1 0.0016 0.0004 0.0005
Onchocerca volvulus 0.0082 0.0354 0.2785
Echinococcus granulosus protein kinase c epsilon type 0.005 0.0187 0.0258
Brugia malayi cell division control protein 2 homolog 0.0105 0.0478 0.1925
Echinococcus granulosus Protein kinase C brain isozyme 0.0127 0.0595 0.0818
Trypanosoma brucei unspecified product 0.0067 0.0278 0.1438
Leishmania major cation-transporting ATPase, putative 0.0032 0.0089 0.0401
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0015 0 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0205 0.0282
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0826 0.4284 0.5893
Echinococcus multilocularis smad 0.0033 0.0097 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0262 0.1219
Schistosoma mansoni cyclin B 0.0124 0.0579 0.0796
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0009
Brugia malayi Cathepsin L-like precursor 0.0046 0.0166 0.0666
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Onchocerca volvulus 0.0066 0.0271 0.2134
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0205 0.0729
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0267 0.1333 0.6234
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0016 0.0054
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0056 0.0256
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.2055 0.2827
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Echinococcus granulosus cathepsin b 0.0018 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus multilocularis phosphoserine phosphatase 0.0048 0.0174 0.0239
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0016 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Onchocerca volvulus Peroxidase homolog 0.0082 0.0354 0.2785
Schistosoma mansoni nAChR subunit 0.0015 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0015 0 0.0001
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0016 0.0088
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0452 0.0621
Onchocerca volvulus 0.0015 0 0.0004
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0016 0.0054
Plasmodium vivax Adenylate and Guanylate cyclase catalytic domain containing protein 0.0034 0.0101 0.0452
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0374 0.19 0.2613
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0016 0.0063
Brugia malayi Na,K-ATPase alpha subunit 0.0258 0.1286 0.5177
Brugia malayi Animal haem peroxidase family protein 0.0082 0.0354 0.1425
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0419 0.2137 0.2939
Trichomonas vaginalis cyclins, putative 0.0064 0.0262 0.1219
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0007 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0016 0.0067
Trichomonas vaginalis DNA polymerase eta, putative 0.0098 0.0438 0.2047
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0032 0.0092 0.0127
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.057 0.0784
Brugia malayi fibroinase precursor 0.0018 0.0016 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0092 0.0371
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0006 0.0021
Echinococcus multilocularis jun protein 0.0084 0.0367 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0012
Toxoplasma gondii P-type ATPase PMA1 0.0156 0.0746 0.2689
Schistosoma mansoni hypothetical protein 0.0041 0.0141 0.0194
Trypanosoma cruzi cysteine peptidase, putative 0.01 0.0451 0.0565
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0029 0.0073 0.0101
Trypanosoma cruzi DNA polymerase eta, putative 0.0122 0.0569 0.0714
Trypanosoma cruzi cysteine peptidase, putative 0.1512 0.7913 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0002
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0199 0.0972 0.1336
Giardia lamblia Encystation-specific protease 0.0018 0.0016 0.0088
Onchocerca volvulus Peroxidasin homolog 0.0082 0.0354 0.2785
Echinococcus granulosus cathepsin l1 0.0046 0.0166 0.0228
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0037 0.0116 0.016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0046 0.0166 0.0666
Onchocerca volvulus 0.0022 0.0036 0.0283
Loa Loa (eye worm) hypothetical protein 0.0102 0.0458 0.1845
Schistosoma mansoni smad 0.0033 0.0097 0.0133
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0006 0.001
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0084 0.0365 0.0502
Echinococcus granulosus protein jagged 1 0.0026 0.0062 0.0085
Echinococcus granulosus neural cadherin 0.0026 0.0062 0.0085
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0016 0.0054
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0015 0 0.0001
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0097 0.0133
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0166 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0205 0.0282
Leishmania major calcium motive p-type ATPase, putative 0.0213 0.1046 0.4885
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Giardia lamblia Cysteine protease 0.0018 0.0016 0.0088
Echinococcus multilocularis phosphoserine phosphatase 0.0048 0.0174 0.0239
Entamoeba histolytica hypothetical protein 0.0077 0.0327 0.2433
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Schistosoma mansoni neurotransmitter gated ion channel 0.0015 0 0.0001
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 1
Loa Loa (eye worm) transcription factor SMAD2 0.0485 0.2484 1
Onchocerca volvulus 0.0026 0.0062 0.0484
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0032 0.0092 0.0127
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0342 0.1224
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0179 0.0867 0.077
Schistosoma mansoni diacylglycerol kinase theta 0.0019 0.0023 0.0032
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0108 0.0494 0.062
Loa Loa (eye worm) ctsf protein 0.0046 0.0166 0.0666
Echinococcus granulosus cyclin t1 0.0016 0.0004 0.0005
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0032 0.0092 0.0371
Brugia malayi Hr1 repeat family protein 0.0029 0.0073 0.0295
Brugia malayi Thioredoxin reductase 0.0046 0.0164 0.066
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0097 0.0389
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0016 0.0054
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0032 0.0092 0.0371
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0056 0.0077
Brugia malayi diacylglycerol kinase 0.0019 0.0023 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0012
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0026 0.0062 0.0484
Trypanosoma brucei trypanothione reductase 0.0046 0.0164 0.0839
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0116 0.0845
Brugia malayi Cation transporter family protein 0.0032 0.0092 0.0371
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0079 0.0341 0.2537
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0048 0.0174 0.0616
Plasmodium falciparum cyclin 0.0064 0.0262 0.12
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0116 0.0845
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0079 0.0341 0.0427
Trichomonas vaginalis cation-transporting ATPase, putative 0.0035 0.0104 0.0482
Giardia lamblia Myb 1-like protein 0.0094 0.0421 0.3139
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0258 0.1286 0.5177
Loa Loa (eye worm) cysteine protease 0.0046 0.0166 0.0666
Brugia malayi Cathepsin L-like precursor 0.0046 0.0166 0.0666
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0006 0.0014
Onchocerca volvulus 0.0026 0.0062 0.0484
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0006 0.001
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0105 0.0478 0.1925
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0032 0.0092 0.0127
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0205 0.0254
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0032 0.0092 0.0127
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0213 0.1046 0.1317
Echinococcus multilocularis GPCR, family 2 0.0032 0.0092 0.0126
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0007 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0595 0.0818
Onchocerca volvulus Protein CNPPD1 homolog 0.0016 0.0004 0.0031
Echinococcus granulosus cathepsin L 0.0037 0.0116 0.016
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0035 0.0104 0.0527
Brugia malayi MH2 domain containing protein 0.0033 0.0097 0.0389
Schistosoma mansoni terminal deoxycytidyl transferase 0.0098 0.0438 0.0603
Echinococcus granulosus Smad4 0.0033 0.0097 0.0133
Entamoeba histolytica deoxycytidyl transferase, putative 0.0098 0.0438 0.3268
Loa Loa (eye worm) animal heme peroxidase 0.0082 0.0354 0.1425
Echinococcus multilocularis cathepsin b 0.0018 0.0016 0.0022
Echinococcus granulosus cysteine protease 0.0037 0.0116 0.016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Onchocerca volvulus 0.0028 0.0072 0.0565
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0046 0.0166 0.0666
Schistosoma mansoni hypothetical protein 0.0032 0.0092 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0067
Brugia malayi isocitrate dehydrogenase 0.0016 0.0007 0.0028
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Brugia malayi E1-E2 ATPase family protein 0.0079 0.0341 0.1374
Schistosoma mansoni cation-transporting atpase worm 0.0079 0.0341 0.0469
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0032 0.0092 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.002 0.0085
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Brugia malayi Cyclin, N-terminal domain containing protein 0.0124 0.0579 0.2329
Trichomonas vaginalis MYB, putative 0.0095 0.0421 0.1967
Brugia malayi hypothetical protein 0.0125 0.0581 0.2339
Schistosoma mansoni notch 0.0026 0.0062 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0016 0.0022
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0005
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0079 0.0341 0.1592
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0108 0.0494 0.062
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0205 0.0943
Schistosoma mansoni hypothetical protein 0.0036 0.011 0.0152
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0116 0.0589
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0029 0.0073 0.0101
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0136 0.0641 0.0806
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0478 0.0658
Brugia malayi calcium ATPase 0.0108 0.0494 0.1989
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0032 0.0089 0.0643
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.001
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0098 0.0438 0.0603
Entamoeba histolytica diacylglycerol kinase, putative 0.0019 0.0023 0.0143
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0092 0.0126
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0062 0.0085
Onchocerca volvulus 0.0032 0.0093 0.0731
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0092 0.0371
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0035 0.0104 0.0755
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0092 0.0127
Onchocerca volvulus 0.0046 0.0166 0.1302
Onchocerca volvulus Peroxidasin homolog 0.0082 0.0354 0.2785
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0046 0.0166 0.0769
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0079 0.0341 0.1592
Schistosoma mansoni type V p-type atpase isoform 0.0035 0.0104 0.0144
Loa Loa (eye worm) hypothetical protein 0.0077 0.0326 0.1314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0116 0.0589
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0082 0.0356 0.265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Onchocerca volvulus 0.0255 0.1271 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.002 0.0085
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0538 0.2763 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0474 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0016 0.0067
Brugia malayi MH2 domain containing protein 0.0033 0.0097 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0076 0.0351
Trichomonas vaginalis pc-MYB2, putative 0.0094 0.0419 0.1956
Echinococcus granulosus glycine receptor subunit alpha 1 0.0032 0.0092 0.0127
Onchocerca volvulus 0.0015 0 0.0004
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0062 0.0085
Trypanosoma cruzi cysteine peptidase, putative 0.01 0.0451 0.0565
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0032 0.0092 0.0371
Trypanosoma brucei rac serine-threonine kinase, putative 0.0029 0.0073 0.0363
Onchocerca volvulus 0.0154 0.0735 0.5782
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0016 0.0067
Toxoplasma gondii thioredoxin reductase 0.0046 0.0164 0.058
Brugia malayi Cathepsin L-like precursor 0.0046 0.0166 0.0666
Entamoeba histolytica cyclin family protein 0.0064 0.0262 0.1939
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 1
Onchocerca volvulus Putative cubilin 0.0026 0.0062 0.0484
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Toxoplasma gondii AGC kinase 0.0029 0.0073 0.0251
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0016 0.0015
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0094 0.0419 0.1956
Trichomonas vaginalis cyclin B, putative 0.0016 0.0004 0.0012
Schistosoma mansoni septate junction protein 0.0026 0.0062 0.0085
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063
Loa Loa (eye worm) hypothetical protein 0.0419 0.2137 0.8601
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Trypanosoma cruzi cruzipain precursor, putative 0.01 0.0451 0.0565
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0452 0.1818
Trichomonas vaginalis cyclins, putative 0.0016 0.0004 0.0012
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0179 0.0867 0.1203
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0182 0.0882 0.3549
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0807
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.137 0.7159 1
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0062 0.0248
Trichomonas vaginalis cyclin A, putative 0.0124 0.0579 0.2703
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0164 0.066
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0079 0.0341 0.0336
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0082 0.0099
Schistosoma mansoni unc-13 (munc13) 0.0022 0.0036 0.0049
Plasmodium vivax vivapain-3 0.0037 0.0116 0.0523
Onchocerca volvulus 0.0019 0.0023 0.0181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0004 0.0016
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Echinococcus granulosus G1:S specific cyclin D1 0.0016 0.0004 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0016 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0006 0.0021
Giardia lamblia DNA damage repair protein 0.003 0.0082 0.0589
Echinococcus granulosus N chimaerin 0.0019 0.0023 0.0032
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0105 0.0478 0.1925
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0327 0.045
Schistosoma mansoni atpase class VI type 11c 0.005 0.0189 0.026
Loa Loa (eye worm) hypothetical protein 0.0079 0.0341 0.1374
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0289 0.1162
Echinococcus granulosus GPCR family 2 0.0032 0.0092 0.0126
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0536 0.0741
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0048 0.0174 0.0215
Echinococcus multilocularis protein kinase c iota type 0.0048 0.0174 0.024
Trichomonas vaginalis cyclin D, putative 0.0064 0.0262 0.1219
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0224 0.1108 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Onchocerca volvulus 0.0015 0 0.0004
Toxoplasma gondii hypothetical protein 0.0049 0.018 0.0637
Echinococcus multilocularis microtubule associated protein 2 0.1391 0.727 1
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0213 0.1046 0.5462
Plasmodium vivax cation transporting ATPase, putative 0.0079 0.0341 0.1571
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0438 0.2278
Giardia lamblia Cation-transporting ATPase 2, putative 0.0032 0.0089 0.0643
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0029 0.0073 0.0101
Plasmodium vivax P-type ATPase4, putative 0.0422 0.2151 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0016 0.0067
Schistosoma mansoni peroxidasin 0.0082 0.0354 0.0487
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0021 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.057 0.0565
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0092 0.0369
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0016 0.0067
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0006 0.0002
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0105 0.0478 0.1719
Brugia malayi Protein kinase domain containing protein 0.0029 0.0073 0.0295
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0205 0.1054
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0 0.0002
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0032 0.0089 0.0412
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0222 0.1096 0.5129
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0088
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0422 0.2151 1
Trichomonas vaginalis cyclin B3, putative 0.0016 0.0004 0.0012
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Brugia malayi Cadherin domain containing protein 0.0026 0.0062 0.0248
Echinococcus multilocularis Smad4 0.0033 0.0097 0.0133
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.027 0.1348 0.6308
Brugia malayi Cation transporter family protein 0.0105 0.0479 0.1927
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0205 0.0254
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0079 0.0341 0.0336
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.021 0.1034 0.1422
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0016 0.0054
Loa Loa (eye worm) hypothetical protein 0.0046 0.0166 0.0666
Entamoeba histolytica cyclin, putative 0.0124 0.0579 0.4322
Onchocerca volvulus 0.0017 0.0014 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0006 0.0009
Echinococcus granulosus neurogenic locus notch protein 4 0.0026 0.0062 0.0085
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0015 0 0.0002
Schistosoma mansoni peroxidasin 0.0082 0.0354 0.0487
Schistosoma mansoni phospholipid-transporting atpase 0.0035 0.0104 0.0144
Schistosoma mansoni hypothetical protein 0.1217 0.6354 0.8739
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0079 0.0341 0.0469
Echinococcus multilocularis phosphoserine phosphatase 0.0048 0.0174 0.0239
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0079 0.0341 0.0427
Brugia malayi Animal haem peroxidase family protein 0.0082 0.0354 0.1425
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0016 0.0088
Schistosoma mansoni phosphoserine phosphatase 0.0048 0.0174 0.0239
Trypanosoma cruzi cysteine protease, putative 0.0037 0.0116 0.0142
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0032 0.0092 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0016 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Giardia lamblia Cathepsin L precursor 0.0018 0.0016 0.0088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.024 0.033
Trichomonas vaginalis cyclin B3, putative 0.0016 0.0004 0.0012
Brugia malayi MAP kinase sur-1 0.0054 0.0205 0.0826
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0046 0.0166 0.0752
Loa Loa (eye worm) hypothetical protein 0.0154 0.0735 0.2959
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0182 0.0882 0.3549
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0037 0.0116 0.016
Trypanosoma brucei protein kinase, putative 0.0054 0.0205 0.1054
Leishmania major copper-transporting ATPase-like protein, putative 0.0079 0.0341 0.1582
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0028 0.0038
Onchocerca volvulus 0.0105 0.0479 0.3766
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0016 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0097 0.0133
Echinococcus granulosus slit 2 protein 0.0026 0.0062 0.0085
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0016 0.0022
Echinococcus multilocularis expressed conserved protein 0.0094 0.042 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0067
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0032 0.0092 0.0127
Toxoplasma gondii cathepsin CPL 0.0046 0.0166 0.0585
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0016 0.0063
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0055 0.0213 0.0756
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0007 0.0028
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0016 0.0004 0.0005
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0048 0.0174 0.0215
Echinococcus granulosus glycine receptor subunit alpha 1 0.0032 0.0092 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0116 0.0538
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0124 0.0579 0.2694
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0097 0.0389
Loa Loa (eye worm) AGC/AKT protein kinase 0.0029 0.0073 0.0295
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Echinococcus granulosus dna polymerase eta 0.0122 0.0569 0.0782
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0008
Plasmodium falciparum E1-E2 ATPase, putative 0.0032 0.0089 0.0398
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0006 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Loa Loa (eye worm) RecQ helicase 0.0025 0.0056 0.0225
Echinococcus granulosus cyclin dependent kinase 1 0.0105 0.0478 0.0658
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0073 0.0101
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0035 0.0104 0.0482
Trypanosoma cruzi cdc2-related kinase 3 0.0105 0.0478 0.06
Loa Loa (eye worm) hypothetical protein 0.0077 0.0329 0.1326
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Schistosoma mansoni DNA polymerase eta 0.0122 0.0569 0.0782
Echinococcus granulosus cyclin b3 0.0064 0.0262 0.036
Loa Loa (eye worm) animal heme peroxidase 0.0082 0.0354 0.1425
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0046 0.0166 0.0228
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Echinococcus multilocularis glycine receptor subunit beta 0.0032 0.0092 0.0127
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0116 0.0468
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0032 0.0089 0.0643
Brugia malayi MH1 domain containing protein 0.0018 0.0019 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0091
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0062 0.0085
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0016 0.0054
Brugia malayi hypothetical protein 0.0015 0 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0116 0.0468
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0022 0.0036 0.0049
Echinococcus multilocularis glycine receptor subunit beta 0.0032 0.0092 0.0127
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 0.6238
Echinococcus multilocularis cyclin dependent kinase 0.0105 0.0478 0.0658
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0072 0.0289
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0019 0.0023 0.0032
Entamoeba histolytica hypothetical protein 0.0077 0.0327 0.2433
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Brugia malayi hypothetical protein 0.005 0.0189 0.076
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0029 0.0073 0.0101
Plasmodium falciparum thioredoxin reductase 0.0016 0.0006 0.0009
Echinococcus granulosus cyclin G2 0.0016 0.0004 0.0005
Leishmania major DNA damage repair protein, putative 0.003 0.0082 0.0367
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0478 0.0658
Brugia malayi CXXC zinc finger family protein 0.0028 0.0072 0.0289
Loa Loa (eye worm) hypothetical protein 0.0124 0.0579 0.2329
Trichomonas vaginalis cation-transporting ATPase, putative 0.0079 0.0341 0.1592
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0199 0.0972 0.1336
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0092 0.0126
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0079 0.0341 0.0469
Brugia malayi hypothetical protein 0.0015 0 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0649
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0149 0.0601
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0084 0.0365 0.0502
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0019 0.0023 0.0032
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Schistosoma mansoni serine/threonine kinase 0.0029 0.0073 0.0101
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0261
Trypanosoma cruzi P-type H+-ATPase, putative 0.0156 0.0746 0.0938
Echinococcus granulosus cathepsin b 0.0018 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.006 0.0239 0.0962
Loa Loa (eye worm) hypothetical protein 0.0124 0.0579 0.2329
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0092 0.0371
Echinococcus multilocularis cyclin b3 0.0064 0.0262 0.036
Echinococcus multilocularis cathepsin L 0.0037 0.0116 0.016
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0026 0.0062 0.0283
Echinococcus granulosus unc 13 munc13 0.0022 0.0036 0.0049
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.057 0.2655
Echinococcus multilocularis nAChR subunit 0.0032 0.0092 0.0127
Echinococcus multilocularis cyclin k 0.0016 0.0004 0.0005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0092 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0067
Echinococcus granulosus cyclin k 0.0016 0.0004 0.0005
Brugia malayi cathepsin F-like cysteine proteinase 0.0019 0.0023 0.0091
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0015 0 0.0002
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0013 0.004
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0056 0.0225
Schistosoma mansoni g1/s-specific cyclin C 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0082 0.0411
Onchocerca volvulus 0.0026 0.0062 0.0484
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Schistosoma mansoni hypothetical protein 0.0404 0.2055 0.2827
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0263 0.1313 0.1655
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0035 0.0104 0.0482
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0007 0.001
Schistosoma mansoni notch 0.0026 0.0062 0.0085
Trypanosoma cruzi proton motive ATPase 1, putative 0.0048 0.0174 0.0215
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0536 0.0741
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0482
Loa Loa (eye worm) animal heme peroxidase 0.0082 0.0354 0.1425
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0021 0.0034 0.0139
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.002 0.0085
Toxoplasma gondii Copper-exporting ATPase 0.0032 0.0089 0.031
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0538 0.2763 0.2759
Onchocerca volvulus 0.0018 0.0016 0.0123
Echinococcus multilocularis neuropeptide s receptor 0.0927 0.4821 0.6632
Leishmania major P-type ATPase, putative 0.0224 0.1108 0.5177
Echinococcus granulosus phospholipid transporting ATPase VA 0.005 0.0189 0.026
Onchocerca volvulus Cathepsin F homolog 0.0046 0.0166 0.1302
Leishmania major DNA polymerase kappa, putative 0.0098 0.0438 0.2037
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Echinococcus granulosus cyclins 0.0064 0.0262 0.036
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0095 0.0421 0.1967
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0162 0.0776 0.581
Brugia malayi cyclin fold protein 1 variant b 0.0016 0.0004 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0073 0.0101
Echinococcus granulosus phospholipid transporting ATPase IF 0.0035 0.0104 0.0144
Trypanosoma brucei P-type H+-ATPase, putative 0.0156 0.0746 0.389
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0082 0.0354 0.1425
Entamoeba histolytica hypothetical protein 0.0018 0.0016 0.0088
Loa Loa (eye worm) LGC-31 protein 0.0032 0.0092 0.0371
Leishmania major cyclin 0.0124 0.0579 0.2694
Schistosoma mansoni smad1 5 8 and 0.0033 0.0097 0.0133
Schistosoma mansoni neurotransmitter gated ion channel 0.0015 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0076 0.0351
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0164 0.0226
Trichomonas vaginalis cyclins, putative 0.0124 0.0579 0.2703
Loa Loa (eye worm) notch protein 0.0026 0.0062 0.0248
Toxoplasma gondii proton ATPase, putative 0.0032 0.0089 0.031
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0092 0.0371
Leishmania major proton motive ATPase, putative 0.0079 0.0341 0.1582
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0088
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0116 0.0845
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Trichomonas vaginalis pc-MYB2, putative 0.0094 0.0419 0.1956
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0088
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0016 0.0004 0.0005
Echinococcus multilocularis copper transporting ATPase 1 0.0079 0.0341 0.0469
Echinococcus granulosus cathepsin L 0.0018 0.0016 0.0022
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0035 0.0104 0.0127
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0164 0.0202
Onchocerca volvulus 0.0046 0.0166 0.1302
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0092 0.0369
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.03 0.1507 0.6066
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0089 0.0412
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0106 0.048 0.1725
Echinococcus granulosus cathepsin L cysteine protease 0.0037 0.0116 0.016
Plasmodium falciparum cysteine proteinase falcipain 3 0.0046 0.0166 0.0752
Echinococcus multilocularis phosphoserine phosphatase 0.0048 0.0174 0.0239
Schistosoma mansoni notch 0.0026 0.0062 0.0085
Loa Loa (eye worm) E1-E2 ATPase 0.0156 0.0746 0.3003
Echinococcus multilocularis neurogenic locus notch protein 4 0.0026 0.0062 0.0085
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0032 0.0092 0.0127
Schistosoma mansoni patched 1 0.0043 0.0149 0.0205
Giardia lamblia Hypothetical protein 0.0018 0.0016 0.0088
Trypanosoma brucei cdc2-related kinase 3 0.0105 0.0478 0.2486
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0474 0.0654
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0438 0.0549
Onchocerca volvulus Peroxidase homolog 0.0082 0.0354 0.2785
Brugia malayi protein kinase C3,putative 0.0021 0.0034 0.0139
Giardia lamblia Copper-transporting P-type ATPase 0.0079 0.0341 0.2537
Trypanosoma cruzi major cysteine proteinase, putative 0.0072 0.0301 0.0375
Schistosoma mansoni cation-transporting ATPase 0.0079 0.0341 0.0469
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0016 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0016 0.0088
Echinococcus granulosus cation transporting atpase worm 0.0079 0.0341 0.0469
Schistosoma mansoni cell polarity protein 0.0026 0.0062 0.0085
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0098 0.0438 0.1765
Echinococcus multilocularis serine:threonine protein kinase N2 0.0029 0.0073 0.0101
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0482
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0164 0.0787 0.1093
Brugia malayi Animal haem peroxidase family protein 0.0082 0.0354 0.1425
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0082 0.0099
Brugia malayi polk-prov protein 0.003 0.0082 0.0331
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0082 0.0284
Trypanosoma cruzi P-type H+-ATPase, putative 0.0108 0.0494 0.062
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0422 0.2151 0.2959
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0159 0.0761 0.5697
Schistosoma mansoni nAChR subunit 0.0015 0 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0016 0.0063
Trypanosoma brucei phospholipid-transporting ATPase, putative 0.0032 0.0089 0.0448
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0258 0.1286 0.9644
Echinococcus granulosus cpg binding protein 0.003 0.008 0.011
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0035 0.0104 0.042
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0094 0.0419 0.1956
Onchocerca volvulus 0.0082 0.0354 0.2785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0164 0.0221
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0029 0.0073 0.0295
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0032 0.0092 0.0127
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0097 0.0133
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0298 0.1495 0.6019
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0062 0.0248
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0224 0.1108 0.1524
Echinococcus multilocularis chromobox protein 1 0.0074 0.0311 0.0428
Toxoplasma gondii cation-transporting atpase family protein 0.0048 0.0174 0.0616
Giardia lamblia G2/mitotic-specific cyclin B 0.0124 0.0579 0.4322
Echinococcus granulosus bloom syndrome protein 0.0025 0.0056 0.0077
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0016 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Brugia malayi C1-like domain containing protein 0.0021 0.0034 0.0139
Trypanosoma cruzi DNA polymerase eta, putative 0.0055 0.0213 0.0264
Echinococcus granulosus dnaJ subfamily B 0.0404 0.2055 0.2827
Brugia malayi excitatory GABA receptor EXP-1A 0.0032 0.0092 0.0371
Echinococcus multilocularis notch 0.0026 0.0062 0.0085
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0342 0.1572
Trichomonas vaginalis cyclin B, putative 0.0124 0.0579 0.2703
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0026 0.0062 0.0085
Echinococcus multilocularis cyclin A3 4 0.0016 0.0004 0.0005
Loa Loa (eye worm) calcium ATPase 0.0162 0.0776 0.3125
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0032 0.0092 0.0371
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0023 0.0091
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0016 0.0067
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0004
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0062 0.0248
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0342 0.1771
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0004 0.0016
Schistosoma mansoni hypothetical protein 0.0041 0.0141 0.0194
Echinococcus granulosus jun protein 0.0084 0.0367 0.0505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Giardia lamblia Cysteine protease 0.0018 0.0016 0.0088
Trichomonas vaginalis MYB72, putative 0.0094 0.0419 0.1956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0016 0.0123
Onchocerca volvulus 0.0019 0.0023 0.0181
Loa Loa (eye worm) Smad1 0.0033 0.0097 0.0389
Echinococcus multilocularis cation transporting ATPase 13A1 0.0079 0.0341 0.0469
Giardia lamblia Cathepsin L precursor 0.0018 0.0016 0.0088
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0438 0.0549
Loa Loa (eye worm) hypothetical protein 0.0133 0.0626 0.2522
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Brugia malayi Cathepsin L-like precursor 0.0027 0.0065 0.0261
Plasmodium falciparum glutathione reductase 0.0046 0.0164 0.0745
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0006 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Onchocerca volvulus 0.0046 0.0166 0.1302
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0164 0.0745
Leishmania major calcium-translocating P-type ATPase 0.0419 0.2137 1
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0035 0.0104 0.0527
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0327 0.045
Brugia malayi notch-like transmembrane receptor 0.0026 0.0062 0.0248
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0082 0.0284
Loa Loa (eye worm) nuclear factor I 0.0018 0.0019 0.0075
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Schistosoma mansoni unc-13 (munc13) 0.0024 0.0046 0.0064
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Brugia malayi hypothetical protein 0.0082 0.0354 0.1425
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0016 0.0088
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0048 0.0174 0.0616
Trypanosoma brucei calcium-transporting ATPase, putative 0.0035 0.0104 0.0527
Leishmania major DNA polymerase eta, putative 0.0055 0.0213 0.0978
Echinococcus granulosus cyclins 0.0064 0.0262 0.036
Schistosoma mansoni phospholipid-transporting atpase 0.0035 0.0104 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0149 0.0693
Echinococcus granulosus cyclins 0.0064 0.0262 0.036
Echinococcus multilocularis dna polymerase kappa 0.0098 0.0438 0.0603
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0019 0.0023 0.0093
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0079 0.0341 0.2537
Plasmodium falciparum guanylyl cyclase 0.0032 0.0089 0.0398
Echinococcus granulosus dna polymerase kappa 0.0098 0.0438 0.0603
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0019 0.0023 0.0093
Loa Loa (eye worm) Notch2 0.0026 0.0062 0.0248
Schistosoma mansoni cyclin d 0.0016 0.0004 0.0005
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0032 0.0092 0.0127
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0098 0.0438 0.2037
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0062 0.0085
Loa Loa (eye worm) hypothetical protein 0.0043 0.0149 0.0601
Echinococcus multilocularis sodium channel protein 0.0155 0.0743 0.1023
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Echinococcus granulosus cathepsin l cysteine peptidase 0.0046 0.0166 0.0228
Brugia malayi RhoGAP domain containing protein 0.0019 0.0023 0.0093
Trypanosoma brucei unspecified product 0.0067 0.0278 0.1438
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0008
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0032 0.0092 0.0371
Plasmodium vivax unspecified product 0.0037 0.0116 0.0523
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0092 0.0127
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0015 0 0.0001
Leishmania major cathepsin L-like protease 0.0046 0.0166 0.0757
Onchocerca volvulus 0.0026 0.0062 0.0484
Trichomonas vaginalis cation-transporting ATPase, putative 0.0032 0.0089 0.0412
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0004 0.0016
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0016 0.0054
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0035 0.0104 0.0127
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0029 0.0073 0.0295
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Trichomonas vaginalis cyclins, putative 0.0124 0.0579 0.2703
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0021 0.0034 0.0047
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0162 0.0778 0.3131
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0474 0.0654
Giardia lamblia Cysteine protease 0.0018 0.0016 0.0088
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Trichomonas vaginalis cyclin B, putative 0.0064 0.0262 0.1219
Brugia malayi MH2 domain containing protein 0.0485 0.2484 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0032 0.0092 0.0127
Echinococcus granulosus notch 0.0026 0.0062 0.0085
Echinococcus granulosus cyclin A3 4 0.0016 0.0004 0.0005
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0016 0.0054
Schistosoma mansoni slit 0.0026 0.0062 0.0085
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0006 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0067
Brugia malayi hypothetical protein 0.0016 0.0004 0.0016
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0062 0.0085
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0094 0.0419 0.1956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Leishmania major P-type H -ATPase, putative 0.0156 0.0746 0.3479
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.002 0.0085
Brugia malayi p70 ribosomal S6 kinase beta 0.0029 0.0073 0.0295
Trichomonas vaginalis C-MYB, putative 0.0094 0.0419 0.1956
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0079 0.0341 0.1769
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0267 0.1333 0.1681
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0079 0.0341 0.1223
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0376 0.1911 0.2629
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0095 0.0421 0.1967
Trypanosoma brucei cdc2-related kinase 1 0.0105 0.0478 0.2486
Trypanosoma cruzi cruzipain precursor, putative 0.1512 0.7913 1
Loa Loa (eye worm) GABA receptor subunit 0.0017 0.0014 0.0055
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0016 0.0063
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0458 0.1845
Trypanosoma brucei mitotic cyclin 6 0.0124 0.0579 0.3013
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0032 0.0092 0.0127
Echinococcus multilocularis serine:threonine protein kinase N2 0.0029 0.0073 0.0101
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0081 0.035 0.0438
Plasmodium vivax unspecified product 0.0019 0.0023 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0065 0.0297
Echinococcus granulosus cyclin y 0.0016 0.0004 0.0005
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0088
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0116 0.0845
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0088
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0035 0.0104 0.0755
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.057 0.0789
Toxoplasma gondii P-type ATPase4, putative 0.0258 0.1286 0.4647
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Onchocerca volvulus Putative nachr subunit 0.0032 0.0092 0.0725
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0536 0.0741
Schistosoma mansoni na+/k+ atpase alpha subunit 0.021 0.1034 0.1422
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Echinococcus granulosus copper transporting ATPase 1 0.0079 0.0341 0.0469
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0084 0.0365 0.1471
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0029 0.0073 0.0101
Trypanosoma cruzi cysteine proteinase, putative 0.0037 0.0116 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0004 0.0016
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0016 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0068 0.0283 0.039
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.009 0.04 0.1611
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0649
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0002
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.137 0.7159 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0205 0.0282
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.005 0.0187 0.0754
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.057 0.0565
Trichomonas vaginalis cyclin B, putative 0.0124 0.0579 0.2703
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Brugia malayi diacylglycerol kinase 0.0019 0.0023 0.0093
Schistosoma mansoni neurotransmitter gated ion channel 0.0017 0.0014 0.0019
Echinococcus granulosus cyclin dependent kinase 0.0105 0.0478 0.0658
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0035 0.0104 0.0482
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 0.6238
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0679 0.0934
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0311 0.145
Entamoeba histolytica cysteine protease, putative 0.0046 0.0166 0.1215
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0438 0.2278
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0017 0.0014 0.0055
Entamoeba histolytica cyclin family protein 0.0064 0.0262 0.1939
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0023 0.0032
Echinococcus multilocularis raf serine:threonine protein kinase 0.0019 0.0023 0.0032
Leishmania major calcium-transporting ATPase, putative 0.0213 0.1046 0.4885
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.0014 0.0055
Echinococcus granulosus peroxidasin 0.0082 0.0354 0.0487
Trypanosoma brucei DNA polymerase eta, putative 0.0122 0.0569 0.2962
Schistosoma mansoni smad1 5 8 and 0.0033 0.0097 0.0133
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0157 0.0727
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0082 0.0099
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.057 0.0784
Trypanosoma brucei unspecified product 0.0098 0.0438 0.2278
Giardia lamblia DINP protein human, muc B family 0.0098 0.0438 0.3268
Echinococcus multilocularis protein kinase c eta type 0.0019 0.0023 0.0032
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 0.6238
Plasmodium vivax vivapain-2 0.0046 0.0166 0.0752
Trichomonas vaginalis cyclin B, putative 0.0016 0.0004 0.0012
Brugia malayi Cyclin, N-terminal domain containing protein 0.0124 0.0579 0.2329
Schistosoma mansoni hypothetical protein 0.0041 0.0141 0.0194
Schistosoma mansoni chromobox protein 0.0074 0.0311 0.0428
Brugia malayi Variant SH3 domain containing protein 0.0019 0.0023 0.0093
Entamoeba histolytica diacylglycerol kinase, putative 0.0019 0.0023 0.0143
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0079 0.0341 0.0469
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0065 0.0458
Echinococcus granulosus cyclin G2 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0096 0.043 0.1733
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0056 0.0256
Trichomonas vaginalis cation-transporting ATPase, putative 0.0267 0.1333 0.6238
Echinococcus granulosus phospholipid transporting ATPase IA 0.0035 0.0104 0.0144
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Brugia malayi cathepsin L precursor 0.0018 0.0016 0.0063
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Loa Loa (eye worm) hypothetical protein 0.0032 0.0089 0.036
Mycobacterium ulcerans hypothetical protein 0.003 0.0082 0.0076
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0026 0.0062 0.0248
Brugia malayi hypothetical protein 0.0077 0.0327 0.1318
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0538 0.2763 0.3552
Echinococcus granulosus cyclin B 0.0124 0.0579 0.0796
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0035 0.0104 0.0144
Entamoeba histolytica cysteine proteinase 1, putative 0.0037 0.0116 0.0845
Entamoeba histolytica protein kinase, putative 0.0029 0.0073 0.0521
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0004 0.0012
Echinococcus granulosus myotubularin protein 13 0.0019 0.0023 0.0032
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0032 0.0092 0.0127
Echinococcus multilocularis cyclin 0.0016 0.0004 0.0005
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0255 0.1271 0.1266
Echinococcus granulosus neuropeptide receptor A26 0.0927 0.4821 0.6632
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.021 0.1034 0.775
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0035 0.0104 0.0144
Brugia malayi cathepsin L-like precursor 0.0027 0.0065 0.0261
Onchocerca volvulus Huntingtin homolog 0.0125 0.0581 0.4572
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0267 0.1333 0.697
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0478 0.2233
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0082 0.0411
Loa Loa (eye worm) AGC/PKN protein kinase 0.0029 0.0073 0.0295
Trypanosoma cruzi cdc2-related kinase 1 0.0105 0.0478 0.06
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0019 0.0023 0.0032
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0079 0.0341 0.0469
Echinococcus multilocularis cyclin y 0.0016 0.0004 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0478 0.2233
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0035 0.0104 0.0144
Schistosoma mansoni protein kinase C mu 0.0019 0.0023 0.0032
Giardia lamblia High cysteine protein 0.0026 0.0062 0.0433
Echinococcus multilocularis G1:S specific cyclin D1 0.0016 0.0004 0.0005
Echinococcus multilocularis chromobox protein 1 0.0074 0.0311 0.0428
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0032 0.0092 0.0127
Schistosoma mansoni hypothetical protein 0.0026 0.0062 0.0085
Brugia malayi Potential phospholipid-transporting ATPase IA 0.0032 0.0089 0.036
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0105 0.0479 0.0658
Leishmania major aminophospholipid translocase, putative 0.0035 0.0104 0.0471
Chlamydia trachomatis metal transport ATPase 0.0079 0.0341 0.0336
Echinococcus multilocularis Cyclin L1 0.0016 0.0004 0.0005
Brugia malayi ImpB/MucB/SamB family protein 0.0122 0.0569 0.229
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.014 0.1102
Echinococcus granulosus nAChR subunit 0.0032 0.0092 0.0127
Echinococcus granulosus cathepsin L cysteine proteinase 0.0046 0.0166 0.0228
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0005
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0035 0.0104 0.0755
Schistosoma mansoni smad1 5 8 and 0.0033 0.0097 0.0133
Entamoeba histolytica hypothetical protein 0.0077 0.0327 0.2433
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0015 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Onchocerca volvulus Cyclin L homolog 0.0016 0.0004 0.0031
Trichomonas vaginalis MYB3r3, putative 0.0094 0.0419 0.1956
Brugia malayi bZIP transcription factor family protein 0.0084 0.0367 0.1477
Echinococcus granulosus cathepsin l1 0.0027 0.0065 0.0089
Toxoplasma gondii cation-transporting ATPase, putative 0.0032 0.0089 0.031
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0538 0.2763 0.2759
Trypanosoma cruzi copper-transporting ATPase, putative 0.0048 0.0174 0.0215
Brugia malayi Peroxidasin 0.0082 0.0354 0.1425
Echinococcus granulosus chromobox protein 1 0.0074 0.0311 0.0428
Brugia malayi Papain family cysteine protease containing protein 0.0046 0.0166 0.0666
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0012
Schistosoma mansoni hypothetical protein 0.1217 0.6354 0.8739
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0149 0.0205
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0208 0.1019 0.7637
Echinococcus granulosus protein kinase C gamma type 0.0108 0.0494 0.0679
Trypanosoma cruzi P-type H+-ATPase, putative 0.0156 0.0746 0.0938
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0006 0.0007
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0157 0.1232
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0015 0 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0006 0.0002
Toxoplasma gondii cathepsin CPC1 0.0018 0.0016 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063
Brugia malayi E1-E2 ATPase family protein 0.0159 0.0761 0.3063
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Giardia lamblia Cathepsin L precursor 0.0018 0.0016 0.0088
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0035 0.0104 0.0471
Schistosoma mansoni copper ABC transporter ATPase 0.0079 0.0341 0.0469
Leishmania major hypothetical protein, conserved 0.0079 0.0342 0.1583
Echinococcus multilocularis protein dispatched 1 0.0049 0.0181 0.025
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0422 0.2151 0.2147
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0079 0.0341 0.2537
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Echinococcus granulosus neurogenic locus protein delta 0.0026 0.0062 0.0085
Onchocerca volvulus 0.0046 0.0166 0.1302
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Schistosoma mansoni hypothetical protein 0.0041 0.0141 0.0194
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0267 0.1333 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0564
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.0278 0.1438
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0016 0.0054
Schistosoma mansoni cpg binding protein 0.003 0.008 0.011
Entamoeba histolytica cyclin, putative 0.0064 0.0262 0.1939
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus multilocularis cyclin dependent kinase 1 0.0105 0.0478 0.0658
Echinococcus multilocularis cyclins 0.0064 0.0262 0.036
Onchocerca volvulus 0.0027 0.0065 0.051
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0012
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0016 0.0015
Giardia lamblia Cathepsin L precursor 0.0018 0.0016 0.0088
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0269 0.1345 0.486
Loa Loa (eye worm) hypothetical protein 0.012 0.0556 0.2239
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0032 0.0092 0.0371
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0094 0.0419 0.3122
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0438 0.0549
Echinococcus multilocularis protein jagged 1 0.0026 0.0062 0.0085
Trypanosoma cruzi cdc2-related kinase 1 0.0105 0.0478 0.06
Loa Loa (eye worm) blistered cuticle protein 3 0.0082 0.0354 0.1425
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0123 0.0571 0.4267
Onchocerca volvulus Neurogenic locus notch homolog 0.0026 0.0062 0.0484
Onchocerca volvulus Slit protein homolog 0.0026 0.0062 0.0484
Echinococcus granulosus Cyclin L1 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus multilocularis RNA directed DNA polymerase 0.0077 0.0329 0.0453
Loa Loa (eye worm) hypothetical protein 0.0099 0.0447 0.1801
Plasmodium falciparum thioredoxin reductase 0.0046 0.0164 0.0745
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0108 0.0494 0.1776
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0458 0.1845
Entamoeba histolytica cell division protein kinase 2, putative 0.0105 0.0478 0.3567
Trichomonas vaginalis cation-transporting ATPase, putative 0.0035 0.0104 0.0482
Schistosoma mansoni notch 0.0026 0.0062 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0016 0.0067
Leishmania major P-type H -ATPase, putative 0.0156 0.0746 0.3479
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Echinococcus multilocularis cyclin B3 1 0.0064 0.0262 0.036
Schistosoma mansoni acetylcholine receptor subunit beta 0.0015 0 0.0001
Echinococcus multilocularis unc 13 (munc13) 0.0022 0.0036 0.0049
Plasmodium falciparum cation transporting P-ATPase 0.0032 0.0089 0.0398
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0342 0.0427
Brugia malayi hypothetical protein 0.0079 0.0342 0.1375
Onchocerca volvulus 0.0082 0.0354 0.2785
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0079 0.0341 0.0336
Schistosoma mansoni phospholipid-transporting atpase 0.0034 0.0101 0.0139
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0079 0.0341 0.0469
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0016 0.0063
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.001
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1907 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0034 0.0047
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0032 0.0092 0.0371
Echinococcus granulosus neuropeptide s receptor 0.0927 0.4821 0.6632
Brugia malayi Cathepsin L-like cysteine proteinase 0.0027 0.0065 0.0261
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Schistosoma mansoni diacylglycerol kinase theta 0.0019 0.0023 0.0032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0 0.0002
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0022 0.0036 0.0049
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0155 0.0743 0.3467
Echinococcus granulosus cyclins 0.0016 0.0004 0.0005
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0016 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0082 0.0411
Schistosoma mansoni cyclin k 0.0016 0.0004 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0034 0.0047
Onchocerca volvulus 0.0105 0.0479 0.3766
Loa Loa (eye worm) acetylcholine receptor protein 0.0015 0 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0073 0.0101
Plasmodium vivax glutathione reductase, putative 0.0046 0.0164 0.0745
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0166 0.0228
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0267 0.1333 0.697
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0035 0.0104 0.0527
Onchocerca volvulus 0.0046 0.0166 0.1302
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.027 0.1348 0.1855
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.057 0.0565
Echinococcus multilocularis cyclin y 0.0016 0.0004 0.0005
Schistosoma mansoni cyclin G 0.0016 0.0004 0.0005
Trichomonas vaginalis cation-transporting ATPase, putative 0.0419 0.2137 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0016 0.0054
Echinococcus granulosus glycine receptor subunit beta 0.0032 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus multilocularis phospholipid transporting ATPase VA 0.005 0.0189 0.026
Echinococcus granulosus Rac GTPase activating protein 1 0.0019 0.0023 0.0032
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0016 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Echinococcus multilocularis phosphoserine phosphatase 0.0048 0.0174 0.0239
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0369
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0016 0.0067
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0032 0.0092 0.0371
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0088
Brugia malayi hypothetical protein 0.0066 0.0271 0.1092
Schistosoma mansoni ATPase 0.0419 0.2137 0.2939
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0105 0.0478 0.2224
Brugia malayi Membrane calcium atpase protein 3 0.0224 0.1108 0.4461
Trypanosoma cruzi cyclin 6, putative 0.0124 0.0579 0.0727
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0037 0.0116 0.016
Echinococcus multilocularis cyclin dependent kinase 1 0.0105 0.0478 0.0658
Onchocerca volvulus 0.0026 0.0062 0.0484
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Toxoplasma gondii diacylglycerol kinase, putative 0.0019 0.0023 0.0069
Brugia malayi Cathepsin L-like precursor 0.0046 0.0166 0.0666
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0016 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0002
Echinococcus granulosus serine:threonine protein kinase N2 0.0029 0.0073 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0082 0.0411
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0327 0.045
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0092 0.0371
Loa Loa (eye worm) hypothetical protein 0.0148 0.0703 0.2832
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0032 0.0092 0.0371
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0166 0.0228
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0032 0.0092 0.0127
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0092 0.0371
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0205 0.0954
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0367 0.0505
Trichomonas vaginalis cation-transporting ATPase, putative 0.0035 0.0104 0.0482
Entamoeba histolytica hypothetical protein 0.0019 0.0023 0.0143
Echinococcus multilocularis cyclin G2 0.0016 0.0004 0.0005
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0062 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0187 0.0258
Mycobacterium tuberculosis Probable reductase 0.0104 0.0474 0.0654
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Echinococcus multilocularis calcium transporting atpase 0.0376 0.1911 0.2629
Echinococcus granulosus fibropellin Ia 0.0026 0.0062 0.0085
Trichomonas vaginalis cyclin B, putative 0.0124 0.0579 0.2703
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0224 0.1108 0.1524
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0267 0.1333 0.6238
Echinococcus multilocularis N chimaerin 0.0019 0.0023 0.0032
Onchocerca volvulus 0.0016 0.0004 0.0031
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0029 0.0073 0.0295
Brugia malayi Cyclin C 0.0016 0.0004 0.0016
Entamoeba histolytica protein kinase, putative 0.0029 0.0073 0.0521
Echinococcus multilocularis protein kinase c epsilon type 0.005 0.0187 0.0258
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0035 0.0104 0.0755
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0032 0.0092 0.0127
Schistosoma mansoni cpg binding protein 0.003 0.008 0.011
Schistosoma mansoni hypothetical protein 0.0019 0.0023 0.0032
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0032 0.0092 0.0127
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0205 0.0254
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0016 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0016 0.0054
Loa Loa (eye worm) fibroinase 0.0046 0.0166 0.0666
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0006 0.0009
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0016 0.0063
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0094 0.0419 0.3122
Brugia malayi Protein kinase c protein 2 0.0101 0.0455 0.1831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0016 0.0063
Loa Loa (eye worm) RasGEF domain-containing protein 0.0019 0.0023 0.0093
Echinococcus granulosus smad 0.0033 0.0097 0.0133
Echinococcus multilocularis neuropeptide receptor A26 0.0927 0.4821 0.6632
Echinococcus granulosus cyclin 0.0016 0.0004 0.0005
Brugia malayi ImpB/MucB/SamB family protein 0.0098 0.0438 0.1765
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0092 0.0371
Echinococcus multilocularis slit 2 protein 0.0026 0.0062 0.0085
Brugia malayi Muscle positioning protein 4 0.0026 0.0062 0.0248
Loa Loa (eye worm) hypothetical protein 0.0105 0.0479 0.1927
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0035 0.0104 0.0755
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0098 0.0438 0.0603
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0438 0.0549
Echinococcus granulosus protein jagged 2 0.0026 0.0062 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0205 0.0954
Onchocerca volvulus 0.0124 0.0579 0.4552
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0032 0.0092 0.0127
Brugia malayi Cadherin domain containing protein 0.0026 0.0062 0.0248
Echinococcus multilocularis cyclin B 0.0124 0.0579 0.0796
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0016 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0166 0.0769
Brugia malayi MH1 domain containing protein 0.0033 0.0097 0.0389
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0105 0.0478 0.0658
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0035 0.0104 0.0755
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0098 0.0438 0.0605
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0009
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Echinococcus granulosus Diacylglycerol kinase theta 0.0019 0.0023 0.0032
Loa Loa (eye worm) cathepsin B 0.0018 0.0016 0.0063
Schistosoma mansoni protein kinase C 0.0022 0.0036 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0116 0.0538
Brugia malayi hypothetical protein 0.0051 0.0193 0.0777
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0016
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0016 0.0042
Brugia malayi Delta serrate ligand family protein 0.0026 0.0062 0.0248
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0006 0.0009
Trichomonas vaginalis cyclin D, putative 0.0016 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0105 0.0479 0.1927
Brugia malayi EGF-like domain containing protein 0.0026 0.0062 0.0248
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0016 0.0063
Echinococcus multilocularis cation transporting ATPase 13A3 0.0079 0.0341 0.0469
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0016 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0067
Brugia malayi Blistered cuticle protein 3 0.0082 0.0354 0.1425
Leishmania major trypanothione reductase 0.0046 0.0164 0.075
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0004 0.0016
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0097 0.0133
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Loa Loa (eye worm) hypothetical protein 0.0082 0.0354 0.1425
Onchocerca volvulus 0.0133 0.0626 0.4929
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0419 0.2137 0.2939
Loa Loa (eye worm) ACC-1 protein 0.0032 0.0092 0.0371
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0096 0.0427 0.0587
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0032 0.0092 0.0127
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0006 0.0023
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0021 0.0034 0.0139
Plasmodium vivax vivapain-2 0.0046 0.0166 0.0752
Echinococcus granulosus protein kinase c iota type 0.0048 0.0174 0.024
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0267 0.1333 0.6238
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0367 0.0505
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Toxoplasma gondii cathepsin B 0.0018 0.0016 0.0042
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0016 0.0004 0.0005
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.0065 0.0089
Plasmodium vivax calcium-transporting ATPase, putative 0.0422 0.2151 1
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0094 0.0419 0.1956
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0046 0.0166 0.0752
Echinococcus multilocularis dna polymerase eta 0.0122 0.0569 0.0782
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0032 0.0092 0.0371
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0376 0.1911 0.2629
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0035 0.0104 0.042
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0016 0.0015
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0016 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0205 0.0943
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.011 0.0152
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Plasmodium falciparum protein kinase 5 0.0105 0.0478 0.2208
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0016 0.0022
Trypanosoma brucei cation-transporting ATPase, putative 0.0079 0.0341 0.1769
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Echinococcus multilocularis fat cadherin tumor suppressor 0.0026 0.0062 0.0085
Onchocerca volvulus Cathepsin L homolog 0.0046 0.0166 0.1302
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0016 0.0004 0.0016
Trichomonas vaginalis cyclin B3, putative 0.0064 0.0262 0.1219
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0007 0.0011
Plasmodium falciparum copper-transporting ATPase 0.0079 0.0341 0.1571
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0015 0 0.0001
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0032 0.0089 0.0643
Giardia lamblia hypothetical protein 0.0032 0.0089 0.0643
Leishmania major cathepsin L-like protease 0.0046 0.0166 0.0757
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0311 0.145
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0016 0.0022
Leishmania major cathepsin L-like protease 0.0046 0.0166 0.0757
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0474 0.0654
Giardia lamblia Hypothetical protein 0.0064 0.0262 0.1939
Giardia lamblia Cathepsin L-like protease 0.0018 0.0016 0.0088
Plasmodium vivax unspecified product 0.0018 0.0016 0.0054
Brugia malayi hypothetical protein 0.0154 0.0735 0.2959
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0007 0.001
Schistosoma mansoni cathepsin C 0.0018 0.0016 0.0022
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.015 0.0714 0.2875
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.057 0.0784
Trichomonas vaginalis cyclin A, putative 0.0016 0.0004 0.0012
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0062 0.0085
Echinococcus multilocularis cathepsin b 0.0018 0.0016 0.0022
Trichomonas vaginalis cation-transporting ATPase, putative 0.0419 0.2137 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0046 0.0166 0.0769
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0015 0 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.0278 0.1438
Brugia malayi hypothetical protein 0.0015 0 0.0002
Brugia malayi RhoGAP domain containing protein 0.0019 0.0023 0.0093
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Schistosoma mansoni cation-transporting atpase fly 0.0032 0.0089 0.0123
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0105 0.0478 0.2224
Schistosoma mansoni hypothetical protein 0.0032 0.0092 0.0126
Loa Loa (eye worm) hypothetical protein 0.0125 0.0581 0.2339
Loa Loa (eye worm) MH2 domain-containing protein 0.0485 0.2484 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0145
Loa Loa (eye worm) hypothetical protein 0.0079 0.0342 0.1375
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.0014 0.0055
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0016 0.0063
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0097 0.0133
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0105 0.0478 0.1925
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0205 0.0282
Plasmodium falciparum calcium-transporting ATPase 0.0374 0.19 0.8827
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0094 0.0419 0.3122
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0224 0.1108 0.1524
Trichomonas vaginalis cyclin D, putative 0.0064 0.0262 0.1219
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0155 0.0743 0.1023
Loa Loa (eye worm) hypothetical protein 0.024 0.1192 0.4799
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0037 0.0116 0.0142
Loa Loa (eye worm) AGC/NDR protein kinase 0.0029 0.0073 0.0295
Leishmania major cysteine peptidase A (CPA) 0.0046 0.0166 0.0757
Echinococcus multilocularis cyclin dependent kinase 5 0.0105 0.0478 0.0658
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0098 0.0438 0.0603
Echinococcus multilocularis cysteine protease 0.0046 0.0166 0.0228
Onchocerca volvulus Cyclin L homolog 0.0016 0.0004 0.0031
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.057 0.2052
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0342 0.1572
Trypanosoma brucei P-type H+-ATPase, putative 0.0156 0.0746 0.389
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0082 0.0411
Onchocerca volvulus 0.0032 0.0092 0.0725
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.027 0.1348 0.1855
Brugia malayi Cathepsin L-like precursor 0.0027 0.0065 0.0261
Loa Loa (eye worm) hypothetical protein 0.0032 0.0092 0.0371
Schistosoma mansoni nAChR subunit 0.0032 0.0092 0.0127
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0679 0.0934
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0079 0.0341 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0166 0.0769
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0258 0.1286 0.1769
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0096 0.0427 0.0587
Schistosoma mansoni Cyclin fold protein 0.0016 0.0004 0.0005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0006 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0451 0.2342
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0157 0.0727
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0094 0.0419 0.3122
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0179 0.0867 0.0861
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0079 0.0341 0.1374
Onchocerca volvulus 0.0017 0.0014 0.0108
Brugia malayi hypothetical protein 0.0016 0.0004 0.0016
Schistosoma mansoni microtubule-associated protein tau 0.1391 0.727 1
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0032 0.0092 0.0127
Brugia malayi Animal haem peroxidase family protein 0.0082 0.0354 0.1425
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Toxoplasma gondii EGF family domain-containing protein 0.0026 0.0062 0.0209
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0164 0.0226
Plasmodium falciparum glutathione reductase 0.0016 0.0006 0.0009
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0096 0.0427 0.318
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.057 0.0784
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Trypanosoma cruzi cyclin, putative 0.0124 0.0579 0.0727
Schistosoma mansoni hypothetical protein 0.0077 0.0327 0.045
Schistosoma mansoni cathepsin s 0.0019 0.0023 0.0031
Echinococcus granulosus expressed conserved protein 0.0094 0.042 0.0577
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1907 1 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.046 0.0632
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0055
Giardia lamblia Cathepsin B precursor 0.0018 0.0016 0.0088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.002 0.0085
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0082 0.0099
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0092 0.0369
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0004 0.0016
Echinococcus granulosus cyclin dependent kinase 5 0.0105 0.0478 0.0658
Echinococcus multilocularis serine:threonine protein kinase 38 0.0029 0.0073 0.0101
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Trypanosoma brucei calcium-transporting ATPase, putative 0.0136 0.0641 0.3341
Echinococcus granulosus RNA directed DNA polymerase 0.0077 0.0329 0.0453
Brugia malayi Smad1 0.0033 0.0097 0.0389
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0092 0.0127
Schistosoma mansoni cation-transporting atpase worm 0.0032 0.0089 0.0123
Onchocerca volvulus 0.0032 0.0089 0.0704
Plasmodium falciparum cation transporting ATPase, putative 0.0032 0.0089 0.0398
Loa Loa (eye worm) hypothetical protein 0.0258 0.1286 0.5177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0065 0.0297
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0092 0.0126
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0108 0.0494 0.1989
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0079 0.0341 0.1592
Treponema pallidum hypothetical protein 0.0048 0.0174 0.0168
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0016 0.0067
Echinococcus multilocularis Rac GTPase activating protein 1 0.0019 0.0023 0.0032
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0205 0.0826
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0016 0.0061
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0089 0.0643
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.011 0.0152
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Entamoeba histolytica cysteine protease, putative 0.0037 0.0116 0.0845
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0007 0.0014
Echinococcus multilocularis cathepsin L cysteine protease 0.0046 0.0166 0.0228
Echinococcus granulosus raf serine:threonine protein kinase 0.0019 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0248
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0073 0.0337
Echinococcus granulosus chromobox protein 1 0.0074 0.0311 0.0428
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0063

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 200 nM In vitro inhibitory activity against Cyclin-dependent kinase 1-cyclin B complex from starfish oocytes ChEMBL. 10753466
IC50 (binding) = 200 nM In vitro inhibitory activity against Cyclin-dependent kinase 1-cyclin B complex from starfish oocytes ChEMBL. 10753466
IC50 (binding) = 0.2 uM Inhibition of Cyclin-dependent kinase 1 (CDK1) ChEMBL. 11063606
IC50 (binding) = 0.2 uM Inhibition of Cyclin-dependent kinase 1 (CDK1) ChEMBL. 11063606
IC50 (binding) = 0.4 uM Inhibitory activity against Cyclin-dependent kinase 5 ChEMBL. 11063606
IC50 (binding) = 0.4 uM Inhibitory activity against Cyclin-dependent kinase 5 ChEMBL. 11063606

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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