Detailed information for compound 301875

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 202.251 | Formula: C9H18N2O3
  • H donors: 3 H acceptors: 3 LogP: -2.43 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(NC(=O)[C@H](CC(=O)O)N)C
  • InChi: 1S/C9H18N2O3/c1-3-4-6(2)11-9(14)7(10)5-8(12)13/h6-7H,3-5,10H2,1-2H3,(H,11,14)(H,12,13)/t6?,7-/m0/s1
  • InChiKey: PUEZOSRCZGUCIS-MLWJPKLSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) G-protein coupled receptor 0.0086 0.0228 0.0361
Brugia malayi Serotonin receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis G protein coupled receptor 139 0.0086 0.0228 0.0363
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis somatostatin receptor 0.0086 0.0228 0.0363
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0099 0.029 0.0275
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0064 0.012 0.0192
Echinococcus granulosus peroxidasin 0.0038 0.0001 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0086 0.0228 0.0361
Trypanosoma cruzi aldo/keto reductase, putative 0.0343 0.1444 0.1395
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.1301 0.598 0.9528
Schistosoma mansoni neuropeptide F-like receptor 0.0086 0.0228 0.0361
Onchocerca volvulus 0.0086 0.0228 0.0379
Echinococcus granulosus hypothetical protein 0.0086 0.0228 0.0363
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Onchocerca volvulus 0.0064 0.012 0.0199
Echinococcus multilocularis neuropeptide s receptor 0.0086 0.0228 0.0363
Toxoplasma gondii cytochrome p450 superfamily protein 0.005 0.0057 0.0042
Onchocerca volvulus 0.0265 0.1075 0.1796
Echinococcus multilocularis g protein coupled receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Loa Loa (eye worm) cytochrome P450 family protein 0.0128 0.0424 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.0619 0.275 1
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0343 0.1444 0.2231
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis aldo keto reductase 0.0343 0.1444 0.2302
Echinococcus granulosus twitchin 0.0083 0.0212 0.0338
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0064 0.012 0.0192
Echinococcus granulosus neuropeptides capa receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0064 0.012 0.0192
Brugia malayi Dopamine receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis neuropeptide FF receptor 2 0.0086 0.0228 0.0363
Brugia malayi G protein-coupled receptor F59B2.13 0.0086 0.0228 0.0361
Schistosoma mansoni neuropeptide receptor 0.0086 0.0228 0.0361
Onchocerca volvulus 0.0086 0.0228 0.0379
Echinococcus granulosus biogenic amine 5HT receptor 0.0086 0.0228 0.0363
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0086 0.0228 0.0363
Schistosoma mansoni potassium channel beta 0.0099 0.029 0.046
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0086 0.0228 0.0361
Echinococcus granulosus aldo keto reductase 0.0343 0.1444 0.2302
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0132 0.0208
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus multilocularis serotonin receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis aldehyde reductase 0.0244 0.0973 0.1551
Echinococcus multilocularis neuropeptide Y receptor 0.0086 0.0228 0.0363
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0062 0.0098
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0064 0.012 0.0192
Echinococcus multilocularis g protein coupled receptor 0.0086 0.0228 0.0363
Schistosoma mansoni hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0062 0.0097
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0064 0.012 0.019
Brugia malayi Protein kinase domain containing protein 0.0101 0.0296 0.047
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0132 0.0075
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi hypothetical protein 0.0066 0.0132 0.0209
Onchocerca volvulus 0.0086 0.0228 0.0379
Mycobacterium ulcerans oxidoreductase 0.0343 0.1444 0.2231
Echinococcus granulosus 7TM GPCR rhodopsin 0.0086 0.0228 0.0363
Echinococcus granulosus neuropeptide s receptor 0.0086 0.0228 0.0363
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0066 0.0132 0.0209
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0086 0.0228 0.0361
Echinococcus granulosus neuropeptide receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis sterol O acyltransferase 1 0.0651 0.2903 0.4627
Schistosoma mansoni myosin xvIII 0.0086 0.0228 0.0361
Echinococcus granulosus aldo keto reductase 0.0343 0.1444 0.2302
Brugia malayi cytochrome P450 0.005 0.0057 0.009
Schistosoma mansoni opsin-like receptor 0.0086 0.0228 0.0361
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0086 0.0228 0.0363
Onchocerca volvulus 0.0086 0.0228 0.0379
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis fmrfamide receptor 0.0086 0.0228 0.0363
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0343 0.1444 0.5225
Brugia malayi Dopamine receptor protein 2 0.0086 0.0228 0.0361
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0038 0.0001 0.0002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0086 0.0228 0.0363
Echinococcus granulosus tachykinin peptides receptor 99D 0.0086 0.0228 0.0363
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0343 0.1444 0.5225
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Leishmania major glycerol uptake protein, putative 0.0064 0.012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) MBOAT family protein 0.0064 0.012 0.019
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0467 0.0745
Mycobacterium ulcerans thymidylate synthase 0.1301 0.598 0.9528
Onchocerca volvulus 0.0343 0.1444 0.2413
Mycobacterium tuberculosis Hypothetical protein 0.0619 0.275 0.4332
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Onchocerca volvulus 0.0086 0.0228 0.0379
Schistosoma mansoni hypothetical protein 0.0163 0.059 0.0939
Onchocerca volvulus 0.0086 0.0228 0.0379
Loa Loa (eye worm) hypothetical protein 0.0066 0.0132 0.0209
Schistosoma mansoni histamine h1 receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0064 0.012 0.0192
Schistosoma mansoni hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis 0.0092 0.0253 0.0404
Echinococcus multilocularis epidermal growth factor receptor 0.0165 0.0602 0.0959
Loa Loa (eye worm) melatonin receptor type 1A 0.0086 0.0228 0.0361
Schistosoma mansoni biogenic amine receptor 0.0086 0.0228 0.0361
Loa Loa (eye worm) TK/INSR protein kinase 0.0101 0.0296 0.047
Loa Loa (eye worm) hypothetical protein 0.0066 0.0132 0.0209
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Entamoeba histolytica alcohol dehydrogenase, putative 0.0099 0.029 0.128
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus sterol O acyltransferase 1 0.0651 0.2903 0.4627
Trypanosoma cruzi aldo-keto reductase 0.0343 0.1444 0.1395
Trichomonas vaginalis aldo/keto reductase, putative 0.0343 0.1444 0.5225
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Onchocerca volvulus 0.0343 0.1444 0.2413
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus roundabout 2 0.0038 0.0001 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Brugia malayi sulfakinin receptor protein 0.0086 0.0228 0.0361
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis neuropeptides capa receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) oxidoreductase 0.0343 0.1444 0.23
Loa Loa (eye worm) hypothetical protein 0.0064 0.012 0.019
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus aldehyde reductase 0.0244 0.0973 0.1551
Onchocerca volvulus 0.0343 0.1444 0.2413
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0132 0.0208
Brugia malayi neuropeptide F receptor 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi GnHR receptor homolog 0.0086 0.0228 0.0361
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0038 0.0001 0.0002
Schistosoma mansoni amine GPCR 0.0086 0.0228 0.0361
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0038 0.0001 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Brugia malayi dihydrofolate reductase family protein 0.1363 0.6274 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0095 0.0268 0.0426
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0064 0.012 0.0105
Onchocerca volvulus 0.0086 0.0228 0.0379
Schistosoma mansoni amine GPCR 0.0086 0.0228 0.0361
Echinococcus granulosus hemicentin 1 0.0038 0.0001 0.0002
Toxoplasma gondii aldose reductase, putative 0.0343 0.1444 0.1431
Echinococcus multilocularis g protein coupled receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0086 0.0228 0.0361
Echinococcus multilocularis roundabout 2 0.0105 0.0314 0.0501
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Echinococcus granulosus thymidylate synthase 0.1301 0.598 0.9532
Echinococcus granulosus G protein coupled receptor 139 0.0086 0.0228 0.0363
Loa Loa (eye worm) cytochrome P450 family protein 0.0095 0.0268 0.0426
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0088 0.0234 0.0373
Echinococcus multilocularis dihydrofolate reductase 0.1363 0.6274 1
Echinococcus multilocularis aldo keto reductase 0.0343 0.1444 0.2302
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Schistosoma mansoni nephrin 0.0083 0.0212 0.0336
Echinococcus granulosus allatostatin A receptor 0.0086 0.0228 0.0363
Echinococcus granulosus neuropeptides capa receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0064 0.012 0.019
Schistosoma mansoni amine GPCR 0.0086 0.0228 0.0361
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0099 0.029 0.046
Schistosoma mansoni sterol O-acyltransferase 1 0.0651 0.2903 0.4626
Onchocerca volvulus 0.0343 0.1444 0.2413
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0064 0.012 0.019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0064 0.012 0.0105
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.016 0.0576 0.0835
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0086 0.0228 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.012 0.0384
Schistosoma mansoni aldo-keto reductase 0.0343 0.1444 0.23
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0062 0.0097
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis aldo keto reductase 0.0343 0.1444 0.2302
Mycobacterium tuberculosis Conserved protein 0.0099 0.029 0.0374
Loa Loa (eye worm) hypothetical protein 0.0105 0.0314 0.0499
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.215 1 1
Echinococcus multilocularis insulin receptor 0.0101 0.0296 0.0472
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0066 0.0132 0.0209
Toxoplasma gondii hypothetical protein 0.0064 0.012 0.0105
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Trypanosoma brucei glycerol uptake protein, putative 0.0064 0.012 0.0063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0343 0.1444 0.5225
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0086 0.0228 0.0361
Echinococcus granulosus peptide allatostatin:somatostatin 0.0086 0.0228 0.0363
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.1363 0.6274 1
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.1363 0.6274 1
Loa Loa (eye worm) cytochrome P450 0.005 0.0057 0.009
Leishmania major hypothetical protein, conserved 0.0064 0.012 0.0063
Leishmania major aldo-keto reductase-like protein 0.0343 0.1444 0.1395
Brugia malayi MBOAT family protein 0.0064 0.012 0.019
Schistosoma mansoni growth hormone secretagogue receptor 0.0086 0.0228 0.0361
Echinococcus granulosus neuropeptide FF receptor 2 0.0086 0.0228 0.0363
Schistosoma mansoni cytochrome P450 0.005 0.0057 0.009
Mycobacterium tuberculosis Probable oxidoreductase 0.0343 0.1444 0.2231
Trypanosoma brucei aldo-keto reductase, putative 0.0343 0.1444 0.1395
Trichomonas vaginalis set domain proteins, putative 0.0265 0.1075 0.3876
Brugia malayi Immunoglobulin I-set domain containing protein 0.0233 0.0922 0.1469
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Schistosoma mansoni amine GPCR 0.0086 0.0228 0.0361
Echinococcus granulosus hypothetical protein 0.0343 0.1444 0.2302
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Echinococcus granulosus g protein coupled receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0062 0.0098
Schistosoma mansoni lipoxygenase 0.0052 0.0066 0.0104
Trichomonas vaginalis porcupine, putative 0.0064 0.012 0.0384
Echinococcus granulosus dihydrofolate reductase 0.1363 0.6274 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0086 0.0228 0.0363
Schistosoma mansoni hypothetical protein 0.0086 0.0228 0.0361
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0099 0.029 0.0234
Trypanosoma cruzi aldo/keto reductase, putative 0.0099 0.029 0.0234
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0165 0.0602 0.0959
Brugia malayi G-protein coupled receptor 0.0086 0.0228 0.0361
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0099 0.029 0.0275
Loa Loa (eye worm) acetyltransferase 0.0141 0.0486 0.0774
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0064 0.012 0.0192
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0086 0.0228 0.0363
Trypanosoma cruzi glycerol uptake protein, putative 0.0064 0.012 0.0063
Loa Loa (eye worm) dihydrofolate reductase 0.1363 0.6274 1
Echinococcus granulosus geminin 0.0163 0.059 0.0941
Echinococcus granulosus voltage gated potassium channel subunit 0.0099 0.029 0.0462
Brugia malayi MBOAT family protein 0.0064 0.012 0.019
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0086 0.0228 0.0363
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0062 0.0097
Brugia malayi AKH receptor 0.0086 0.0228 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.012 0.0384
Brugia malayi Serotonin receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis tyrosine protein kinase otk 0.0038 0.0001 0.0002
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0052 0.0066 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0086 0.0228 0.0363
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.029 0.1004
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Schistosoma mansoni tyrosine kinase 0.0158 0.0565 0.0899
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.215 1 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus serotonin receptor 0.0086 0.0228 0.0363
Schistosoma mansoni biogenic amine receptor 0.0086 0.0228 0.0361
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0086 0.0228 0.0361
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0233 0.0923 0.1469
Plasmodium vivax aldehyde reductase, putative 0.0099 0.029 0.0275
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0062 0.0098
Echinococcus granulosus neuropeptide receptor 0.0086 0.0228 0.0363
Onchocerca volvulus 0.0086 0.0228 0.0379
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0343 0.1444 0.23
Brugia malayi MBOAT family protein 0.0064 0.012 0.019
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Loa Loa (eye worm) hypothetical protein 0.0343 0.1444 0.23
Trypanosoma cruzi glycerol uptake protein, putative 0.0064 0.012 0.0063
Trypanosoma brucei cytochrome P450, putative 0.0095 0.0268 0.0212
Brugia malayi Cytochrome P450 family protein 0.0095 0.0268 0.0426
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0343 0.1444 0.1395
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0086 0.0228 0.0361
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0343 0.1444 0.23
Onchocerca volvulus 0.0086 0.0228 0.0379
Loa Loa (eye worm) oxidoreductase 0.0343 0.1444 0.23
Echinococcus multilocularis hemicentin 1 0.0038 0.0001 0.0002
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0343 0.1444 0.23
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0132 0.0087
Schistosoma mansoni zinc finger protein 0.0064 0.012 0.019
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0066 0.0132 0.021
Echinococcus granulosus microtubule associated protein 2 0.078 0.351 0.5595
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus granulosus epidermal growth factor receptor 0.0302 0.1251 0.1994
Brugia malayi Immunoglobulin I-set domain containing protein 0.0066 0.0132 0.0209
Entamoeba histolytica aldose reductase, putative 0.0343 0.1444 1
Echinococcus granulosus roundabout 2 0.0105 0.0314 0.0501
Brugia malayi MBOAT family protein 0.0064 0.012 0.019
Onchocerca volvulus 0.0138 0.0471 0.0786
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis dro:myosuppressin receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) oxidoreductase 0.0343 0.1444 0.23
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0064 0.012 0.0192
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0064 0.012 0.0192
Echinococcus granulosus neuropeptide receptor A26 0.0086 0.0228 0.0363
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0064 0.012 0.019
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0132 0.021
Mycobacterium leprae Conserved hypothetical protein 0.0244 0.0973 0.1474
Onchocerca volvulus 0.1301 0.598 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0132 0.0075
Echinococcus multilocularis orexin receptor type 2 0.0086 0.0228 0.0363
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0086 0.0228 0.0379
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Schistosoma mansoni adenoreceptor 0.0086 0.0228 0.0361
Brugia malayi Hhat protein 0.0064 0.012 0.019
Giardia lamblia Aldose reductase 0.0343 0.1444 1
Onchocerca volvulus 0.0343 0.1444 0.2413
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0064 0.012 0.0192
Onchocerca volvulus 0.0343 0.1444 0.2413
Brugia malayi hypothetical protein 0.0619 0.275 0.4382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Trypanosoma brucei glycerol uptake protein, putative 0.0064 0.012 0.0063
Schistosoma mansoni opsin-like receptor 0.0086 0.0228 0.0361
Echinococcus granulosus contactin 0.0038 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0064 0.012 0.019
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus Immunoglobulin 0.0066 0.0132 0.021
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Echinococcus multilocularis fmrfamide receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis epidermal growth factor receptor 0.0302 0.1251 0.1994
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0099 0.029 0.0275
Leishmania major glycerol uptake protein, putative 0.0064 0.012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Trichomonas vaginalis transmembrane protein nessy, putative 0.0064 0.012 0.0384
Schistosoma mansoni tyrosine kinase 0.0101 0.0296 0.047
Echinococcus granulosus tm gpcr rhodopsin 0.0086 0.0228 0.0363
Echinococcus multilocularis sex peptide receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Loa Loa (eye worm) neuropeptide F receptor 0.0086 0.0228 0.0361
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.1363 0.6274 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0132 0.0075
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Schistosoma mansoni neuropeptide receptor 0.0086 0.0228 0.0361
Brugia malayi diacylglycerol acyltransferase 0.0064 0.012 0.019
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) hhat protein 0.0064 0.012 0.019
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.1301 0.598 0.9528
Brugia malayi putative neuropeptide receptor 0.0086 0.0228 0.0361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Onchocerca volvulus 0.0086 0.0228 0.0379
Mycobacterium leprae Possible oxidoreductase 0.0099 0.029 0.0374
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0233 0.0922 0.1469
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0086 0.0228 0.0363
Echinococcus multilocularis neuropeptide receptor 0.0086 0.0228 0.0363
Trypanosoma cruzi glycerol uptake protein, putative 0.0064 0.012 0.0063
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0099 0.029 0.1004
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0486 0.0774
Leishmania major prostaglandin f synthase, putative 0.0343 0.1444 0.1395
Echinococcus multilocularis neuroglian 0.0083 0.0212 0.0338
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0086 0.0228 0.0363
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0086 0.0228 0.0361
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis G-protein coupled receptor, putative 0.0086 0.0228 0.0363
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.215 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0062 0.0098
Brugia malayi Melatonin receptor type 1A 0.0086 0.0228 0.0361
Echinococcus granulosus aldo keto reductase 0.0343 0.1444 0.2302
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0486 0.0774
Loa Loa (eye worm) thymidylate synthase 0.1301 0.598 0.9532
Echinococcus granulosus tyrosine protein kinase otk 0.0038 0.0001 0.0002
Echinococcus granulosus epidermal growth factor receptor 0.0165 0.0602 0.0959
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0343 0.1444 0.1395
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Trypanosoma cruzi GUP1, putative 0.0064 0.012 0.0063
Echinococcus multilocularis voltage gated potassium channel subunit 0.0099 0.029 0.0462
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0086 0.0228 0.0363
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0086 0.0228 0.0361
Schistosoma mansoni hypothetical protein 0.0163 0.059 0.0939
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.029 0.1004
Brugia malayi NADH-dependent xylose reductase 0.0099 0.029 0.046
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0105 0.0314 0.0499
Leishmania major cytochrome p450-like protein 0.0095 0.0268 0.0212
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0132 0.0208
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0343 0.1444 0.23
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0038 0.0001 0.0002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0086 0.0228 0.0361
Echinococcus granulosus o acyltransferase membrane bound domain 0.0064 0.012 0.0192
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Schistosoma mansoni tyrosine kinase 0.0046 0.0037 0.0058
Schistosoma mansoni hypothetical protein 0.0064 0.012 0.019
Schistosoma mansoni opsin-like receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis aldo keto reductase 0.0343 0.1444 0.2302
Echinococcus granulosus tm gpcr rhodopsin 0.0086 0.0228 0.0363
Brugia malayi RE15519p 0.0086 0.0228 0.0361
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Echinococcus granulosus insulin receptor 0.0101 0.0296 0.0472
Echinococcus multilocularis allatostatin A receptor 0.0086 0.0228 0.0363
Onchocerca volvulus 0.0099 0.029 0.0483
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0086 0.0228 0.0361
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0086 0.0228 0.0361
Mycobacterium ulcerans hypothetical protein 0.0099 0.029 0.0374
Chlamydia trachomatis dihydrofolate reductase 0.1363 0.6274 0.5
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0086 0.0228 0.0361
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.012 0.0384
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Echinococcus multilocularis roundabout 2 0.0038 0.0001 0.0002
Brugia malayi G-protein coupled receptor 0.0086 0.0228 0.0361
Schistosoma mansoni dihydrofolate reductase 0.1363 0.6274 1
Loa Loa (eye worm) MBOAT family protein 0.0064 0.012 0.019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0086 0.0228 0.0361
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Leishmania major glycerol uptake protein, putative 0.0064 0.012 0.0063
Echinococcus granulosus 7tm_1 domain containing protein 0.0086 0.0228 0.0363
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0086 0.0228 0.0361
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus multilocularis Immunoglobulin 0.0066 0.0132 0.021
Entamoeba histolytica aldose reductase, putative 0.0343 0.1444 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus lachesin 0.0038 0.0001 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0086 0.0228 0.0363
Echinococcus granulosus o acyltransferase membrane bound domain 0.0064 0.012 0.0192
Onchocerca volvulus Tyrosine kinase homolog 0.0162 0.0587 0.098
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0038 0.0001 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Loa Loa (eye worm) TK/EGFR protein kinase 0.0302 0.1251 0.1993
Plasmodium falciparum aldo-keto reductase, putative 0.0099 0.029 0.0172
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Echinococcus multilocularis hemicentin 1 0.0038 0.0001 0.0002
Echinococcus multilocularis roundabout 2 0.0038 0.0001 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) oxidoreductase 0.0343 0.1444 0.23
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0064 0.012 0.019
Schistosoma mansoni tyrosine kinase 0.0158 0.0565 0.0899
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus fmrfamide receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) TYRA-2 protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0086 0.0228 0.0363
Brugia malayi Cytochrome P450 family protein 0.0095 0.0268 0.0426
Brugia malayi Pre-SET motif family protein 0.0233 0.0923 0.1469
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi Dihydrofolate reductase 0.1363 0.6274 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Echinococcus multilocularis neuroglian 0.0038 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus orexin receptor type 2 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0064 0.012 0.019
Trypanosoma cruzi GUP1, putative 0.0064 0.012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0651 0.2903 0.4626
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0619 0.275 0.2708
Brugia malayi thymidylate synthase 0.1301 0.598 0.9532
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0101 0.0296 0.0472
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi MBOAT family protein 0.0064 0.012 0.019
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis g-protein coupled receptor 0.0086 0.0228 0.0363
Echinococcus multilocularis lachesin 0.0038 0.0001 0.0002
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0064 0.012 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Onchocerca volvulus 0.0086 0.0228 0.0379
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0086 0.0228 0.0361
Echinococcus multilocularis serotonin receptor 0.0086 0.0228 0.0363
Giardia lamblia Aldose reductase 0.0343 0.1444 1
Trypanosoma cruzi cytochrome P450, putative 0.0095 0.0268 0.0212
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.029 0.1004
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0038 0.0001 0.0002
Brugia malayi neuropeptide F receptor 0.0086 0.0228 0.0361
Echinococcus granulosus neuropeptide Y receptor 0.0086 0.0228 0.0363
Echinococcus granulosus dro:myosuppressin receptor 0.0086 0.0228 0.0363
Onchocerca volvulus 0.0086 0.0228 0.0379
Echinococcus multilocularis neuropeptides capa receptor 0.0086 0.0228 0.0363
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.1369 0.9433
Entamoeba histolytica alcohol dehydrogenase, putative 0.0099 0.029 0.128
Schistosoma mansoni tyrosine kinase 0.0158 0.0565 0.0899
Brugia malayi Fibronectin type III domain containing protein 0.0066 0.0132 0.0209
Schistosoma mansoni hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus g protein coupled receptor 0.0086 0.0228 0.0363
Brugia malayi ORL1-like opioid receptor 0.0086 0.0228 0.0361
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0343 0.1444 0.2302
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0064 0.012 0.0192
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0086 0.0228 0.0361
Schistosoma mansoni neuropeptide f receptor 76f 0.0086 0.0228 0.0361
Brugia malayi follicle stimulating hormone receptor 0.0086 0.0228 0.0361
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0064 0.012 0.019
Onchocerca volvulus 0.0086 0.0228 0.0379
Brugia malayi Tachykinin-like peptides receptor 99D 0.0086 0.0228 0.0361
Echinococcus multilocularis geminin 0.0163 0.059 0.0941
Echinococcus multilocularis neuropeptide receptor A26 0.0086 0.0228 0.0363
Trichomonas vaginalis aldo/keto reductase, putative 0.0343 0.1444 0.5225
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0486 0.0775
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus sex peptide receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis Immunoglobulin 0.0066 0.0132 0.021
Schistosoma mansoni neuropeptide receptor 0.0086 0.0228 0.0361
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.016 0.0576 0.0835
Echinococcus granulosus g protein coupled receptor 0.0086 0.0228 0.0363
Schistosoma mansoni biogenic amine (5HT) receptor 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0099 0.029 0.0462
Echinococcus multilocularis neuropeptide receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0045 0.003 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0062 0.0097
Brugia malayi putative neuropeptide receptor NPR1 0.0086 0.0228 0.0361
Loa Loa (eye worm) neuropeptide F receptor 0.0086 0.0228 0.0361
Onchocerca volvulus 0.0086 0.0228 0.0379
Onchocerca volvulus 0.0086 0.0228 0.0379
Schistosoma mansoni pol-related 0.0343 0.1444 0.23
Echinococcus granulosus neuroglian 0.0083 0.0212 0.0338
Brugia malayi Dopamine receptor protein 1 0.0086 0.0228 0.0361
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Schistosoma mansoni neuropeptide receptor 0.0086 0.0228 0.0361
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Trypanosoma brucei prostaglandin f synthase 0.0343 0.1444 0.1395
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Echinococcus multilocularis 0.005 0.0057 0.0091
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi hypothetical protein 0.0086 0.0228 0.0361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.215 1 1
Trypanosoma brucei aldo/keto reductase, putative 0.0099 0.029 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Echinococcus granulosus g-protein coupled receptor 0.0086 0.0228 0.0363
Schistosoma mansoni tyrosine kinase 0.0101 0.0296 0.047
Loa Loa (eye worm) MBOAT family protein 0.0064 0.012 0.019
Trypanosoma cruzi cytochrome P450, putative 0.0095 0.0268 0.0212
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Loa Loa (eye worm) CYP4Cod1 0.0095 0.0268 0.0426
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis thymidylate synthase 0.1301 0.598 0.9532
Brugia malayi Cytochrome P450 family protein 0.005 0.0057 0.009
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0101 0.0296 0.0472
Leishmania major glycerol uptake protein, putative 0.0064 0.012 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.215 1 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0086 0.0228 0.0361
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0132 0.0075
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0062 0.0097
Echinococcus multilocularis neuropeptide Y receptor 0.0086 0.0228 0.0363
Schistosoma mansoni microtubule-associated protein tau 0.078 0.351 0.5595
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0064 0.012 0.0192
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0095 0.0268 0.034
Toxoplasma gondii aldo-keto reductase 0.0099 0.029 0.0275
Schistosoma mansoni vesicular amine transporter 0.0066 0.0132 0.0209
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0064 0.012 0.0192
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0086 0.0228 0.0361
Onchocerca volvulus 0.0086 0.0228 0.0379
Entamoeba histolytica aldose reductase, putative 0.0343 0.1444 1
Schistosoma mansoni tyrosine kinase 0.0165 0.0602 0.0957
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0086 0.0228 0.0363
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0588 0.2602 0.4146
Brugia malayi Furin-like cysteine rich region family protein 0.0302 0.1251 0.1993
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.1369 0.9433
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0066 0.0132 0.0209
Echinococcus granulosus neuropeptide Y receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) oxidoreductase 0.0343 0.1444 0.23
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Echinococcus multilocularis peroxidasin 0.0038 0.0001 0.0002
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.016 0.0576 0.0835
Plasmodium falciparum aldehyde reductase, putative 0.0099 0.029 0.0172
Echinococcus granulosus somatostatin receptor 0.0086 0.0228 0.0363
Leishmania major glycerol uptake protein, putative 0.0064 0.012 0.0063
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0086 0.0228 0.0363
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) G-protein coupled receptor 0.0086 0.0228 0.0361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0228 0.0361
Onchocerca volvulus Neuropeptide F receptor homolog 0.0086 0.0228 0.0379
Schistosoma mansoni biogenic amine (5HT) receptor 0.0086 0.0228 0.0361
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0064 0.012 0.0192
Trichomonas vaginalis aldo-keto reductase, putative 0.0343 0.1444 0.5225
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.1301 0.598 0.9532
Loa Loa (eye worm) hypothetical protein 0.0066 0.0132 0.0209
Echinococcus granulosus cytochrome P450 2K1 0.005 0.0057 0.0091
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0015 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0228 0.0363
Echinococcus granulosus neuroglian 0.0038 0.0001 0.0002
Onchocerca volvulus 0.0086 0.0228 0.0379
Treponema pallidum fructose-bisphosphate aldolase 0.0327 0.1369 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0132 0.0209
Brugia malayi Cytochrome P450 family protein 0.0128 0.0424 0.0674
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0099 0.029 0.046
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0086 0.0228 0.0361
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0064 0.012 0.019
Schistosoma mansoni biogenic amine receptor 0.0086 0.0228 0.0361
Schistosoma mansoni tyrosine kinase 0.0302 0.1251 0.1993
Echinococcus granulosus o acyltransferase membrane bound domain 0.0064 0.012 0.0192
Brugia malayi G protein-coupled receptor 0.0086 0.0228 0.0361
Schistosoma mansoni aldo-keto reductase 0.0343 0.1444 0.23
Schistosoma mansoni amine GPCR 0.0086 0.0228 0.0361
Schistosoma mansoni hypothetical protein 0.005 0.0057 0.009
Echinococcus granulosus roundabout 2 0.0038 0.0001 0.0002
Schistosoma mansoni cell adhesion molecule 0.0088 0.0234 0.0372
Echinococcus granulosus defective proboscis extension response 0.0066 0.0132 0.021
Echinococcus granulosus alpha 1A adrenergic receptor 0.0086 0.0228 0.0363
Loa Loa (eye worm) hypothetical protein 0.0088 0.0234 0.0372
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0086 0.0228 0.0363
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0052 0.0066 0.0106
Loa Loa (eye worm) hypothetical protein 0.0086 0.0228 0.0361
Brugia malayi larval opioid receptor 0.0086 0.0228 0.0361
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0132 0.021
Trichomonas vaginalis aldo/keto reductase, putative 0.0343 0.1444 0.5225
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.1369 0.495
Echinococcus multilocularis microtubule associated protein 2 0.078 0.351 0.5595
Schistosoma mansoni tyrosine kinase 0.0165 0.0602 0.0957
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.029 0.1004
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0064 0.012 0.019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0132 0.0209
Loa Loa (eye worm) hhat protein 0.0064 0.012 0.019
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0343 0.1444 0.2302

Activities

Activity type Activity value Assay description Source Reference
Taste class (functional) = 0 Quality of taste by acting at receptor site; Tasteless ChEMBL. 3712380

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.